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Anti-Cancer Activity of Derivatives of 1,3,4-Oxadiazole

Department of Chemistry of Drugs, Faculty of Pharmacy, Wroclaw Medical University, Borowska 211, 50-556 Wroclaw, Poland
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Molecules 2018, 23(12), 3361; https://doi.org/10.3390/molecules23123361
Received: 11 December 2018 / Revised: 17 December 2018 / Accepted: 18 December 2018 / Published: 18 December 2018
(This article belongs to the Section Medicinal Chemistry)
Compounds containing 1,3,4-oxadiazole ring in their structure are characterised by multidirectional biological activity. Their anti-proliferative effects associated with various mechanisms, such as inhibition of growth factors, enzymes, kinases and others, deserve attention. The activity of these compounds was tested on cell lines of various cancers. In most publications, the most active derivatives of 1,3,4-oxadiazole exceeded the effect of reference drugs, so they may become the main new anti-cancer drugs in the future. View Full-Text
Keywords: 1,3,4-oxadiazole; anti-proliferative activity; anti-cancer drugs 1,3,4-oxadiazole; anti-proliferative activity; anti-cancer drugs
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Glomb, T.; Szymankiewicz, K.; Świątek, P. Anti-Cancer Activity of Derivatives of 1,3,4-Oxadiazole. Molecules 2018, 23, 3361.

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