Next Article in Journal
Agrimonia eupatoria L. and Cynara cardunculus L. Water Infusions: Comparison of Anti-Diabetic Activities
Next Article in Special Issue
An Aqueous Extract of Tuberaria lignosa Inhibits Cell Growth, Alters the Cell Cycle Profile, and Induces Apoptosis of NCI-H460 Tumor Cells
Previous Article in Journal
Hydrophilic Modification of Multi-Walled Carbon Nanotube for Building Photonic Crystals with Enhanced Color Visibility and Mechanical Strength
Previous Article in Special Issue
Neuroprotective and Cytotoxic Phthalides from Angelicae Sinensis Radix
Open AccessArticle

Antimicrobial Activity and Chromatographic Analysis of Extracts from Tropaeolum pentaphyllum Lam. Tubers

1
Departamento de Farmácia Industrial, Universidade Federal de Santa Maria (UFSM), Avenida Roraima 1000, Block 26, Santa Maria 97105-900, Rio Grande do Sul, Brazil
2
Departamento de Parasitologia, Microbiologia e Imunologia, Universidade Federal de Santa Maria (UFSM), Avenida Roraima 1000, Block 20, Santa Maria 97105-900, Rio Grande do Sul, Brazil
3
Departamento de Análises Clínicas e Toxicológicas, Universidade Federal de Santa Maria (UFSM), Avenida Roraima 1000, Block 26, Santa Maria 97105-900, Rio Grande do Sul, Brazil
*
Author to whom correspondence should be addressed.
Academic Editor: Isabel C. F. R. Ferreira
Molecules 2016, 21(5), 566; https://doi.org/10.3390/molecules21050566
Received: 7 March 2016 / Revised: 4 April 2016 / Accepted: 25 April 2016 / Published: 28 April 2016
(This article belongs to the Collection Bioactive Compounds)
Background: Tropaeolum pentaphyllum Lam. tubers (Tropaeolaceae) are known and used as a condiment and for the treatment of skin infections in Southern Brazil. However, its activity and composition has not yet been investigated. Thus, different extracts and the essential oil from the tubers were tested against a range of microorganisms. The most active extracts were submitted to chromatographic analysis. Methods: Hydroalcoholic extract (70%), fractions of it, and the essential oil from the tubers were tested against several bacteria, yeasts and molds, furnishing the corresponding inhibitory, bactericidal and fungicidal minimal concentration values. The most active extracts were submitted to GC-MS investigation. Results: The strongest effects against different strains of microorganisms, such as Gram-positive and negative bacteria, Candida spp. and dermatophytes were observed for the essential oil and the chloroform fraction, with minimal inhibitory concentrations (MICs) well below 200 µg/mL. GC-MS analysis revealed that the major essential oil constituent is benzyl isothiocyanate (BITC), while the chloroform fraction is constituted of BITC, amides, sulfur, fatty acids and its esters, all compounds that may be related to the demonstrated activity. Conclusions: Overall, the results support the popular use of the plant for the treatment of skin infections, and revealed the main active compounds. View Full-Text
Keywords: Tropaeolum pentaphyllum; essential oil; benzyl isothiocyanate; antifungal; antibacterial Tropaeolum pentaphyllum; essential oil; benzyl isothiocyanate; antifungal; antibacterial
Show Figures

Figure 1

MDPI and ACS Style

Da Cruz, R.C.; Denardi, L.B.; Mossmann, N.J.; Piana, M.; Alves, S.H.; De Campos, M.M.A. Antimicrobial Activity and Chromatographic Analysis of Extracts from Tropaeolum pentaphyllum Lam. Tubers. Molecules 2016, 21, 566.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop