Next Article in Journal
Synthesis and Pharmacological Evaluation of Novel Phenyl Sulfonamide Derivatives Designed as Modulators of Pulmonary Inflammatory Response
Next Article in Special Issue
Sulfation and Enhanced Antioxidant Capacity of an Exopolysaccharide Produced by the Medicinal Fungus Cordyceps sinensis
Previous Article in Journal
Synthesis and Antimicrobial Activity of Some New 1,3,4-Thiadiazole Derivatives
Previous Article in Special Issue
Food Ingredient Extracts of Cyclopia subternata (Honeybush): Variation in Phenolic Composition and Antioxidant Capacity
Open AccessArticle

Synthesis and Antiradical/Antioxidant Activities of Caffeic Acid Phenethyl Ester and Its Related Propionic, Acetic, and Benzoic Acid Analoguesc

Department of Chemistry and Biochemistry, Université de Moncton, Moncton, NB E1A 3E9, Canada
*
Author to whom correspondence should be addressed.
Molecules 2012, 17(12), 14637-14650; https://doi.org/10.3390/molecules171214637
Received: 25 October 2012 / Revised: 9 November 2012 / Accepted: 5 December 2012 / Published: 10 December 2012
(This article belongs to the Special Issue Antioxidants 2012)
Caffeic acid phenethyl ester (CAPE) is a bioactive component isolated from propolis. A series of CAPE analogues was synthesized and their antiradical/antioxidant effects analyzed. The effect of the presence of the double bond and of the conjugated system on the antioxidant effect is evaluated with the analogues obtained from 3-(3,4-dihydroxyphenyl) propanoic acid. Those obtained from 2-(3,4-dihydroxyphenyl) acetic acid and 3,4-dihydroxybenzoic acid allow the evaluation of the effect of the presence of two carbons between the carbonyl and aromatic system. View Full-Text
Keywords: CAPE; caffeic acid; 3-(3,4-dihydroxyphenyl) propanoic acid esters; 2-(3,4-dihydroxyphenyl) acetic acid esters; 3,4-dihydroxybenzoic acid esters; antioxidant CAPE; caffeic acid; 3-(3,4-dihydroxyphenyl) propanoic acid esters; 2-(3,4-dihydroxyphenyl) acetic acid esters; 3,4-dihydroxybenzoic acid esters; antioxidant
Show Figures

Graphical abstract

MDPI and ACS Style

LeBlanc, L.M.; Paré, A.F.; Jean-François, J.; Hébert, M.J.G.; Surette, M.E.; Touaibia, M. Synthesis and Antiradical/Antioxidant Activities of Caffeic Acid Phenethyl Ester and Its Related Propionic, Acetic, and Benzoic Acid Analoguesc. Molecules 2012, 17, 14637-14650.

Show more citation formats Show less citations formats

Article Access Map by Country/Region

1
Only visits after 24 November 2015 are recorded.
Search more from Scilit
 
Search
Back to TopTop