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Molecules 2007, 12(11), 2533-2545;

Synthesis of New L-Ascorbic Ferulic Acid Hybrids

Université de Caen Basse-Normandie, U.F.R. des Sciences Pharmaceutiques, Centre d’Etudes et de Recherche sur le Médicament de Normandie, UPRES EA-3915, 5, rue Vaubénard, 14032 CAEN Cedex, France
Author to whom correspondence should be addressed.
Received: 30 October 2007 / Revised: 15 November 2007 / Accepted: 15 November 2007 / Published: 17 November 2007
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A feasibility and chemical study of the coupling conditions of L-ascorbic acidwith ferulic acid derivatives are described on the basis of the known synergistic effects ofmixtures of various antioxidants. Novel L-ascorbic ferulic hybrids linked at the C-3hydroxyl group were prepared with the aim to protect the alcohol function and the enediolsystem. View Full-Text
Keywords: Ascorbic acid; ferulic acid; hybridization; antioxidant; oxidative stress. Ascorbic acid; ferulic acid; hybridization; antioxidant; oxidative stress.

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This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Voisin-Chiret, A.S.; Bazin, M.-A.; Lancelot, J.-C.; Rault, S. Synthesis of New L-Ascorbic Ferulic Acid Hybrids. Molecules 2007, 12, 2533-2545.

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