Special Issue "Natural Products and Inflammation"
Deadline for manuscript submissions: closed (15 July 2016)
Inflammation (or inflammatory reaction) is the response to body aggression by a pathogen agent, an allergen, a toxic compound, a tissue lesion, etc. It can be a general phenomenon with fever, tiredness, or a local phenomenon with pain and edema. Inflammation is characterized by the production of various active signaling molecules, such as vaso-active amines (histamine/serotonin), prostaglandins, leukotriens, kininogens/kallikreins/kinins, complement factors, cytokines, and MMPs/TIMPs (Tissue Inhibitors of MetalloProteinases). All of the following pathologies present with a strong inflammatory component; infection, injury, vessels atherosclerosis, diabetes mellitus, obesity, cancer, osteo-arthritis, macular eyes degenerescence, demyelination and brain pathologies associated with aging. Inflammation is a complex response that involves among other interactions between activated lymphocytes, dendritic cells (i.e., antigen presenting cells or APCs) and monocytes, subsequently differentiated into macrophages. During this process, numerous cytokines are secreted by immune cells and by injured tissue non-immune cells as a consequence of cell-cell interactions.
The immunomodulation by various compounds, such as natural products, represents a promising preventive or therapeutic strategy against a number of pathological processes. Beside pro-inflammatory cytokines/interleukines, various lipid mediators produced through the arachidonate metabolism also play a key role in in inflammation-linked pathologies, such as atherosclerosis or cancers.
Original papers or review papers reporting the effect of natural products on inflammatory (anti- or pro-) processes are welcome. These compounds can include plant polyphenols, flavonoids or derivatives, lipid omega-6, marine compounds, bacterial extracts, etc.
Dr. Norbert Latruffe
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Natural products
- pro- and anti-inflammatory properties
- plant polyphenols
- marine products
- bacterial extracts