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Molecules 2016, 21(11), 1492; doi:10.3390/molecules21111492

Inflammasomes and Natural Ingredients towards New Anti-Inflammatory Agents

Laboratory BioperoxIL, Faculty of Sciences SVTE, University of Bourgogne Franche Comté, 6 Bd Gabriel F-21000 Dijon, France
Academic Editor: Derek J. McPhee
Received: 10 October 2016 / Revised: 23 October 2016 / Accepted: 25 October 2016 / Published: 8 November 2016
(This article belongs to the Special Issue Natural Products and Inflammation)
View Full-Text   |   Download PDF [1759 KB, uploaded 8 November 2016]   |  

Abstract

Inflammasomes are a family of proteins in charge of the initiation of inflammatory process during innate immune response. They are now considered major actors in many chronic inflammatory diseases. However, no major drug focusing on this target is currently on the market. Among the various approaches aiming to control this major metabolic pathway, compounds aiming to modify the intracellular antioxidant profile appear to be promising. This can be obtained by “light” antioxidants able to induce natural antioxidant response of the cell itself. This review will give an overview of the current available information on this promising pharmacology approach. View Full-Text
Keywords: inflammasomes; natural antioxidants; inflammation inflammasomes; natural antioxidants; inflammation
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Dutartre, P. Inflammasomes and Natural Ingredients towards New Anti-Inflammatory Agents. Molecules 2016, 21, 1492.

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