Special Issue "Advances in Molecular Oncology"

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A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology".

Deadline for manuscript submissions: closed (30 December 2012)

Special Issue Editor

Guest Editor
Dr. William Chi-shing Cho
Department of Clinical Oncology, Queen Elizabeth Hospital, Hong Kong
E-Mail: williamcscho@gmail.com
Interests: cancer biomarker; Chinese medicine; diabetes mellitus; evidence-based medicine; genomics; microRNA; molecular diagnostics; nasopharyngeal carcinoma; non-small cell lung cancer; proteomics

Special Issue Information

Dear Colleagues,

The completion of the human genome project and the availability of high-throughput technologies have led a dramatic change in cancer research. In the past few decades, oncological studies are evolving from traditional to molecular oncology. Numerous researches have contributed to our knowledge of the molecular mechanisms underlying cancer progression, defining pathways that influence cancer therapy and response, as well as developing new tools and therapeutics to prevent or manage cancer more effectively. The field of molecular oncology is growing rapidly and it has a great impact on basic science, clinical study, and translational cancer research. This open-access special issue will bring together original research and review articles on molecular oncology. It highlights new discoveries, approaches, and technical developments in molecular cancer research. The main feature of this special issue is to provide an open-source sharing of significant works in the field of molecular oncology that can advance our understanding of cancer development which may lead to the discovery of novel molecular diagnostic technologies and targeted therapeutics.

Topics of this special issue include, but are not limited to:

  • Key biological processes such as: cell cycle, DNA repair, apoptosis, autophagy, angiogenesis, invasion and metastasis, signaling pathway
  • Molecular tumor pathology
  • Tumor microenvironment
  • Cancer epidemiology and prevention
  • Cancer biomarkers: screening, diagnosis, treatment response, prognosis
  • Cancer therapy: target discovery, drug design, resistance, targeted therapy, theranostics, personalized medicine
  • Translational cancer research
  • High-throughput technologies: genomics, epigenomics, proteomics, metabolomics, microarray, next generation sequencing, and other omics technologies
  • Genomic and proteomic databases and applications

Dr. William C.S. Cho
Guest Editor

Keywords

  • angiogenesis
  • animal models
  • apoptosis
  • autophagy
  • cancer biomarker
  • cancer epidemiology
  • cancer prevention
  • cancer screening
  • cancer stem cells
  • cell cycle
  • clinical trial
  • copy number variation
  • DNA repair
  • epigenomics
  • genome instability
  • genomic database
  • genomics
  • invasion
  • metabolomics
  • metastasis
  • methylation
  • microarray
  • microRNA
  • molecular diagnostics
  • molecular tumor pathology
  • next generation sequencing
  • noncoding RNA
  • omics
  • personalized medicine
  • prognosis
  • proteomics
  • signaling pathway
  • SNP genotyping
  • targeted therapy
  • theranostics
  • therapeutic targets
  • translational cancer research
  • treatment response
  • tumor microenvironment

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Published Papers (49 papers)

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Displaying article 1-49
p. 5587-5607
by ,  and
Int. J. Mol. Sci. 2013, 14(3), 5587-5607; doi:10.3390/ijms14035587
Received: 30 October 2012; in revised form: 26 November 2012 / Accepted: 19 February 2013 / Published: 11 March 2013
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(This article belongs to the Special Issue Advances in Molecular Oncology)
p. 3874-3900
by ,  and
Int. J. Mol. Sci. 2013, 14(2), 3874-3900; doi:10.3390/ijms14023874
Received: 13 September 2012; in revised form: 8 January 2013 / Accepted: 10 January 2013 / Published: 13 February 2013
Show/Hide Abstract | Cited by 3 | PDF Full-text (856 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Advances in Molecular Oncology)
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p. 3314-3324
by ,  and
Int. J. Mol. Sci. 2013, 14(2), 3314-3324; doi:10.3390/ijms14023314
Received: 30 August 2012; in revised form: 9 January 2013 / Accepted: 10 January 2013 / Published: 5 February 2013
Show/Hide Abstract | Cited by 15 | PDF Full-text (186 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Advances in Molecular Oncology)
p. 1370-1382
by , , , , , , , ,  and
Int. J. Mol. Sci. 2013, 14(1), 1370-1382; doi:10.3390/ijms14011370
Received: 6 November 2012; in revised form: 25 December 2012 / Accepted: 25 December 2012 / Published: 11 January 2013
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(This article belongs to the Special Issue Advances in Molecular Oncology)
p. 888-919
by  and
Int. J. Mol. Sci. 2013, 14(1), 888-919; doi:10.3390/ijms14010888
Received: 15 October 2012; in revised form: 6 December 2012 / Accepted: 10 December 2012 / Published: 7 January 2013
Show/Hide Abstract | Cited by 3 | PDF Full-text (572 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Advances in Molecular Oncology)
p. 30-45
by , , , ,  and
Int. J. Mol. Sci. 2013, 14(1), 30-45; doi:10.3390/ijms14010030
Received: 11 October 2012; in revised form: 1 December 2012 / Accepted: 3 December 2012 / Published: 20 December 2012
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(This article belongs to the Special Issue Advances in Molecular Oncology)
p. 108-145
by , ,  and
Int. J. Mol. Sci. 2013, 14(1), 108-145; doi:10.3390/ijms14010108
Received: 15 October 2012; in revised form: 10 December 2012 / Accepted: 12 December 2012 / Published: 20 December 2012
Show/Hide Abstract | Cited by 7 | PDF Full-text (973 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Advances in Molecular Oncology)
p. 16624-16635
by , , , , , ,  and
Int. J. Mol. Sci. 2012, 13(12), 16624-16635; doi:10.3390/ijms131216624
Received: 28 September 2012; in revised form: 20 November 2012 / Accepted: 26 November 2012 / Published: 5 December 2012
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(This article belongs to the Special Issue Advances in Molecular Oncology)
p. 16636-16657
by , , ,  and
Int. J. Mol. Sci. 2012, 13(12), 16636-16657; doi:10.3390/ijms131216636
Received: 11 October 2012; in revised form: 21 November 2012 / Accepted: 27 November 2012 / Published: 5 December 2012
Show/Hide Abstract | Cited by 8 | PDF Full-text (334 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Advances in Molecular Oncology)
p. 16020-16045
by ,  and
Int. J. Mol. Sci. 2012, 13(12), 16020-16045; doi:10.3390/ijms131216020
Received: 17 September 2012; in revised form: 15 November 2012 / Accepted: 19 November 2012 / Published: 28 November 2012
Show/Hide Abstract | Cited by 7 | PDF Full-text (273 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Advances in Molecular Oncology)
p. 15343-15359
by , , ,  and
Int. J. Mol. Sci. 2012, 13(11), 15343-15359; doi:10.3390/ijms131115343
Received: 24 October 2012; in revised form: 13 November 2012 / Accepted: 14 November 2012 / Published: 20 November 2012
Show/Hide Abstract | Cited by 6 | PDF Full-text (453 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Advances in Molecular Oncology)
p. 14962-14972
by , , , , , ,  and
Int. J. Mol. Sci. 2012, 13(11), 14962-14972; doi:10.3390/ijms131114962
Received: 28 August 2012; in revised form: 8 November 2012 / Accepted: 8 November 2012 / Published: 15 November 2012
Show/Hide Abstract | Cited by 2 | PDF Full-text (172 KB) | HTML Full-text | XML Full-text | Supplementary Files
(This article belongs to the Special Issue Advances in Molecular Oncology)
p. 14845-14864
by  and
Int. J. Mol. Sci. 2012, 13(11), 14845-14864; doi:10.3390/ijms131114845
Received: 18 September 2012; in revised form: 16 October 2012 / Accepted: 1 November 2012 / Published: 13 November 2012
Show/Hide Abstract | Cited by 3 | PDF Full-text (309 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Advances in Molecular Oncology)
p. 14667-14678
by , , , , ,  and
Int. J. Mol. Sci. 2012, 13(11), 14667-14678; doi:10.3390/ijms131114667
Received: 26 September 2012; in revised form: 22 October 2012 / Accepted: 5 November 2012 / Published: 12 November 2012
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(This article belongs to the Special Issue Advances in Molecular Oncology)
p. 14518-14532
by , , , ,  and
Int. J. Mol. Sci. 2012, 13(11), 14518-14532; doi:10.3390/ijms131114518
Received: 31 July 2012; in revised form: 1 November 2012 / Accepted: 5 November 2012 / Published: 8 November 2012
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(This article belongs to the Special Issue Advances in Molecular Oncology)
p. 13949-13965
by , , ,  and
Int. J. Mol. Sci. 2012, 13(11), 13949-13965; doi:10.3390/ijms131113949
Received: 27 July 2012; in revised form: 14 September 2012 / Accepted: 17 October 2012 / Published: 29 October 2012
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(This article belongs to the Special Issue Advances in Molecular Oncology)
p. 13764-13780
by , , , , ,  and
Int. J. Mol. Sci. 2012, 13(11), 13764-13780; doi:10.3390/ijms131113764
Received: 13 September 2012; in revised form: 10 October 2012 / Accepted: 16 October 2012 / Published: 24 October 2012
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(This article belongs to the Special Issue Advances in Molecular Oncology)
p. 13737-13747
by ,  and
Int. J. Mol. Sci. 2012, 13(10), 13737-13747; doi:10.3390/ijms131013737
Received: 5 September 2012; in revised form: 16 October 2012 / Accepted: 17 October 2012 / Published: 23 October 2012
Show/Hide Abstract | Cited by 2 | PDF Full-text (165 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Advances in Molecular Oncology)
p. 13621-13666
by , , , ,  and
Int. J. Mol. Sci. 2012, 13(10), 13621-13666; doi:10.3390/ijms131013621
Received: 5 September 2012; in revised form: 8 October 2012 / Accepted: 11 October 2012 / Published: 22 October 2012
Show/Hide Abstract | Cited by 8 | PDF Full-text (1085 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Advances in Molecular Oncology)
p. 13414-13437
by ,  and
Int. J. Mol. Sci. 2012, 13(10), 13414-13437; doi:10.3390/ijms131013414
Received: 27 August 2012; in revised form: 19 September 2012 / Accepted: 9 October 2012 / Published: 18 October 2012
Show/Hide Abstract | Cited by 14 | PDF Full-text (340 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Advances in Molecular Oncology)
p. 13240-13263
by , , ,  and
Int. J. Mol. Sci. 2012, 13(10), 13240-13263; doi:10.3390/ijms131013240
Received: 28 August 2012; in revised form: 8 October 2012 / Accepted: 10 October 2012 / Published: 16 October 2012
Show/Hide Abstract | Cited by 4 | PDF Full-text (233 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Advances in Molecular Oncology)
p. 13183-13202
by , ,  and
Int. J. Mol. Sci. 2012, 13(10), 13183-13202; doi:10.3390/ijms131013183
Received: 15 June 2012; in revised form: 25 August 2012 / Accepted: 8 October 2012 / Published: 15 October 2012
Show/Hide Abstract | Cited by 2 | PDF Full-text (1320 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Advances in Molecular Oncology)
p. 13030-13048
by , , , , ,  and
Int. J. Mol. Sci. 2012, 13(10), 13030-13048; doi:10.3390/ijms131013030
Received: 27 July 2012; in revised form: 8 September 2012 / Accepted: 21 September 2012 / Published: 11 October 2012
Show/Hide Abstract | Cited by 1 | PDF Full-text (1905 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Advances in Molecular Oncology)
p. 12544-12555
by , , ,  and
Int. J. Mol. Sci. 2012, 13(10), 12544-12555; doi:10.3390/ijms131012544
Received: 24 July 2012; in revised form: 31 August 2012 / Accepted: 5 September 2012 / Published: 1 October 2012
Show/Hide Abstract | Cited by 4 | PDF Full-text (183 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Advances in Molecular Oncology)
p. 12556-12572
by , ,  and
Int. J. Mol. Sci. 2012, 13(10), 12556-12572; doi:10.3390/ijms131012556
Received: 1 August 2012; in revised form: 27 August 2012 / Accepted: 27 August 2012 / Published: 1 October 2012
Show/Hide Abstract | Cited by 6 | PDF Full-text (204 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Advances in Molecular Oncology)
p. 12519-12532
by , , ,  and
Int. J. Mol. Sci. 2012, 13(10), 12519-12532; doi:10.3390/ijms131012519
Received: 26 July 2012; in revised form: 18 September 2012 / Accepted: 21 September 2012 / Published: 28 September 2012
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(This article belongs to the Special Issue Advances in Molecular Oncology)
p. 12287-12314
by  and
Int. J. Mol. Sci. 2012, 13(10), 12287-12314; doi:10.3390/ijms131012287
Received: 8 August 2012; in revised form: 14 September 2012 / Accepted: 19 September 2012 / Published: 26 September 2012
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(This article belongs to the Special Issue Advances in Molecular Oncology)
p. 12153-12168
by , , , , , ,  and
Int. J. Mol. Sci. 2012, 13(10), 12153-12168; doi:10.3390/ijms131012153
Received: 26 July 2012; in revised form: 6 September 2012 / Accepted: 6 September 2012 / Published: 25 September 2012
Show/Hide Abstract | Cited by 12 | PDF Full-text (1127 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Advances in Molecular Oncology)
p. 12000-12016
by , , ,  and
Int. J. Mol. Sci. 2012, 13(9), 12000-12016; doi:10.3390/ijms130912000
Received: 16 July 2012; in revised form: 5 September 2012 / Accepted: 11 September 2012 / Published: 20 September 2012
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(This article belongs to the Special Issue Advances in Molecular Oncology)
p. 11530-11542
by , , , , ,  and
Int. J. Mol. Sci. 2012, 13(9), 11530-11542; doi:10.3390/ijms130911530
Received: 7 August 2012; in revised form: 5 September 2012 / Accepted: 6 September 2012 / Published: 14 September 2012
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(This article belongs to the Special Issue Advances in Molecular Oncology)
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p. 11471-11496
by , ,  and
Int. J. Mol. Sci. 2012, 13(9), 11471-11496; doi:10.3390/ijms130911471
Received: 7 August 2012; in revised form: 5 September 2012 / Accepted: 7 September 2012 / Published: 13 September 2012
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(This article belongs to the Special Issue Advances in Molecular Oncology)
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p. 11071-11084
by ,  and
Int. J. Mol. Sci. 2012, 13(9), 11071-11084; doi:10.3390/ijms130911071
Received: 1 August 2012; in revised form: 28 August 2012 / Accepted: 28 August 2012 / Published: 6 September 2012
Show/Hide Abstract | Cited by 10 | PDF Full-text (184 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Advances in Molecular Oncology)
p. 11044-11062
by , , , , ,  and
Int. J. Mol. Sci. 2012, 13(9), 11044-11062; doi:10.3390/ijms130911044
Received: 18 June 2012; in revised form: 22 August 2012 / Accepted: 23 August 2012 / Published: 5 September 2012
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(This article belongs to the Special Issue Advances in Molecular Oncology)
p. 10959-10969
by , , , , ,  and
Int. J. Mol. Sci. 2012, 13(9), 10959-10969; doi:10.3390/ijms130910959
Received: 26 July 2012; in revised form: 14 August 2012 / Accepted: 27 August 2012 / Published: 31 August 2012
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(This article belongs to the Special Issue Advances in Molecular Oncology)
p. 10736-10749
by , , , , , , , ,  and
Int. J. Mol. Sci. 2012, 13(9), 10736-10749; doi:10.3390/ijms130910736
Received: 7 June 2012; in revised form: 21 August 2012 / Accepted: 22 August 2012 / Published: 27 August 2012
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(This article belongs to the Special Issue Advances in Molecular Oncology)
p. 10176-10192
by , , , , , ,  and
Int. J. Mol. Sci. 2012, 13(8), 10176-10192; doi:10.3390/ijms130810176
Received: 5 June 2012; in revised form: 3 August 2012 / Accepted: 7 August 2012 / Published: 15 August 2012
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(This article belongs to the Special Issue Advances in Molecular Oncology)
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p. 8762-8774
by , , , , ,  and
Int. J. Mol. Sci. 2012, 13(7), 8762-8774; doi:10.3390/ijms13078762
Received: 23 May 2012; in revised form: 19 June 2012 / Accepted: 6 July 2012 / Published: 16 July 2012
Show/Hide Abstract | Cited by 14 | PDF Full-text (1240 KB) | HTML Full-text | XML Full-text | Supplementary Files
(This article belongs to the Special Issue Advances in Molecular Oncology)
p. 8482-8499
by , , , , , , , ,  and
Int. J. Mol. Sci. 2012, 13(7), 8482-8499; doi:10.3390/ijms13078482
Received: 23 April 2012; in revised form: 14 June 2012 / Accepted: 2 July 2012 / Published: 9 July 2012
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(This article belongs to the Special Issue Advances in Molecular Oncology)
p. 8353-8363
by , , , , ,  and
Int. J. Mol. Sci. 2012, 13(7), 8353-8363; doi:10.3390/ijms13078353
Received: 4 June 2012; in revised form: 28 June 2012 / Accepted: 29 June 2012 / Published: 5 July 2012
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(This article belongs to the Special Issue Advances in Molecular Oncology)
p. 8259-8272
by , , , , , , , , , ,  and
Int. J. Mol. Sci. 2012, 13(7), 8259-8272; doi:10.3390/ijms13078259
Received: 30 May 2012; in revised form: 19 June 2012 / Accepted: 27 June 2012 / Published: 3 July 2012
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(This article belongs to the Special Issue Advances in Molecular Oncology)
p. 7663-7675
by , , , , , ,  and
Int. J. Mol. Sci. 2012, 13(6), 7663-7675; doi:10.3390/ijms13067663
Received: 11 April 2012; in revised form: 15 June 2012 / Accepted: 19 June 2012 / Published: 21 June 2012
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(This article belongs to the Special Issue Advances in Molecular Oncology)
p. 6983-6994
by , , , , , , ,  and
Int. J. Mol. Sci. 2012, 13(6), 6983-6994; doi:10.3390/ijms13066983
Received: 7 April 2012; in revised form: 25 May 2012 / Accepted: 1 June 2012 / Published: 7 June 2012
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(This article belongs to the Special Issue Advances in Molecular Oncology)
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p. 6849-6862
by , ,  and
Int. J. Mol. Sci. 2012, 13(6), 6849-6862; doi:10.3390/ijms13066849
Received: 20 April 2012; in revised form: 19 May 2012 / Accepted: 22 May 2012 / Published: 5 June 2012
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(This article belongs to the Special Issue Advances in Molecular Oncology)
p. 6679-6697
by ,  and
Int. J. Mol. Sci. 2012, 13(6), 6679-6697; doi:10.3390/ijms13066679
Received: 19 April 2012; in revised form: 21 May 2012 / Accepted: 22 May 2012 / Published: 1 June 2012
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p. 6352-6369
by , , , , , ,  and
Int. J. Mol. Sci. 2012, 13(5), 6352-6369; doi:10.3390/ijms13056352
Received: 9 April 2012; in revised form: 9 May 2012 / Accepted: 18 May 2012 / Published: 23 May 2012
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(This article belongs to the Special Issue Advances in Molecular Oncology)
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p. 6399-6406
by , , , , ,  and
Int. J. Mol. Sci. 2012, 13(5), 6399-6406; doi:10.3390/ijms13056399
Received: 18 April 2012; in revised form: 15 May 2012 / Accepted: 15 May 2012 / Published: 23 May 2012
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(This article belongs to the Special Issue Advances in Molecular Oncology)
p. 6204-6219
by , , , , , , , , , ,  and
Int. J. Mol. Sci. 2012, 13(5), 6204-6219; doi:10.3390/ijms13056204
Received: 22 March 2012; in revised form: 24 April 2012 / Accepted: 9 May 2012 / Published: 21 May 2012
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(This article belongs to the Special Issue Advances in Molecular Oncology)
p. 5519-5527
by , ,  and
Int. J. Mol. Sci. 2012, 13(5), 5519-5527; doi:10.3390/ijms13055519
Received: 10 April 2012; in revised form: 26 April 2012 / Accepted: 27 April 2012 / Published: 8 May 2012
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p. 4367-4387
by , , , , , , , , , ,  and
Int. J. Mol. Sci. 2012, 13(4), 4367-4387; doi:10.3390/ijms13044367
Received: 1 March 2012; in revised form: 20 March 2012 / Accepted: 23 March 2012 / Published: 5 April 2012
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Last update: 26 February 2014

Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert