Special Issue "Advances in Molecular Oncology 2014"


A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology".

Deadline for manuscript submissions: 31 December 2014

Special Issue Editor

Guest Editor
Dr. William Chi-shing Cho
Department of Clinical Oncology, Queen Elizabeth Hospital, Hong Kong
E-Mail: williamcscho@gmail.com
Interests: cancer biomarker; Chinese medicine; diabetes mellitus; evidence-based medicine; genomics; microRNA; molecular diagnostics; nasopharyngeal carcinoma; non-small cell lung cancer; proteomics

Special Issue Information

Dear Colleagues,

The completion of the human genome project and the availability of high-throughput technologies have led a dramatic change in cancer research. In the past few decades, oncological studies are evolving from traditional to molecular oncology. Numerous researches have contributed to our knowledge of the molecular mechanisms underlying cancer progression, defining pathways that influence cancer therapy and response, as well as developing new tools and therapeutics to prevent or manage cancer more effectively. The field of molecular oncology is growing rapidly and it has a great impact on basic science, clinical study, and translational cancer research. This open-access special issue will bring together original research and review articles on molecular oncology. It highlights new discoveries, approaches, and technical developments in molecular cancer research. The main feature of this special issue is to provide an open-source sharing of significant works in the field of molecular oncology that can advance our understanding of cancer development which may lead to the discovery of novel molecular diagnostic technologies and targeted therapeutics.

Topics of this special issue include, but are not limited to:

●     Key biological processes such as: genome instability, checkpoints, cell cycle, DNA repair, apoptosis, autophagy, angiogenesis, invasion and metastasis, signaling pathway, "drivers" versus "passengers"

●     Molecular tumor pathology

●     Tumor microenvironment

●     Cancer epidemiology and prevention

●     Cancer biomarkers: screening, diagnosis, treatment response, prognosis

●     Cancer therapy: target discovery, drug design, resistance, targeted therapy, theranostics, personalized medicine

●     Translational cancer research

●     High-throughput technologies: genomics, epigenomics, proteomics, metabolomics, microarray, next generation sequencing, and other omics technologies

●     Genomic and proteomic databases and applications

Dr. William Cho
Guest Editor

Similar Special Issues are available at:
Special Issue "Advances in Molecular Oncology"


Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed Open Access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs).


  • angiogenesis
  • animal models
  • apoptosis
  • autophagy
  • cancer biomarker
  • cancer epidemiology
  • cancer prevention
  • cancer screening
  • cancer stem cells
  • cell cycle
  • clinical decision-making
  • CLIA (Clinical Laboratory Improvement Amendments)
  • clinical trial
  • copy number variation
  • DNA repair
  • epigenomics
  • gene expression profiling
  • genome instability
  • genomic database
  • genomics
  • invasion
  • metabolomics
  • metastasis
  • methylation
  • microarray
  • microRNA
  • molecular diagnostics
  • molecular tumor pathology
  • next generation sequencing
  • oncogenic driver
  • noncoding RNA
  • omics
  • personalized medicine
  • precision medicine
  • prognosis
  • functional proteomics
  • signaling pathway
  • SNP genotyping
  • targeted therapy
  • theranostics
  • therapeutic targets
  • translational cancer research
  • treatment response
  • tumor microenvironment

Published Papers (6 papers)

Int. J. Mol. Sci. 2014, 15(7), 11539-11554; doi:10.3390/ijms150711539
Received: 30 April 2014; in revised form: 17 June 2014 / Accepted: 20 June 2014 / Published: 27 June 2014
Show/Hide Abstract | PDF Full-text (1937 KB)
abstract graphic

Int. J. Mol. Sci. 2014, 15(6), 9718-9734; doi:10.3390/ijms15069718
Received: 1 May 2014; in revised form: 16 May 2014 / Accepted: 22 May 2014 / Published: 30 May 2014
Show/Hide Abstract | PDF Full-text (1616 KB) | HTML Full-text | XML Full-text | Supplementary Files

Int. J. Mol. Sci. 2014, 15(5), 8458-8472; doi:10.3390/ijms15058458
Received: 8 March 2014; in revised form: 17 April 2014 / Accepted: 18 April 2014 / Published: 13 May 2014
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Int. J. Mol. Sci. 2014, 15(5), 7124-7138; doi:10.3390/ijms15057124
Received: 22 February 2014; in revised form: 16 March 2014 / Accepted: 10 April 2014 / Published: 25 April 2014
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Int. J. Mol. Sci. 2014, 15(4), 6544-6555; doi:10.3390/ijms15046544
Received: 13 March 2014; in revised form: 28 March 2014 / Accepted: 9 April 2014 / Published: 17 April 2014
Show/Hide Abstract | PDF Full-text (474 KB) | HTML Full-text | XML Full-text

Int. J. Mol. Sci. 2014, 15(4), 5292-5303; doi:10.3390/ijms15045292
Received: 30 December 2013; in revised form: 1 March 2014 / Accepted: 17 March 2014 / Published: 26 March 2014
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Last update: 17 February 2014

Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert