Special Issue "Molecular Research in Urology"
Deadline for manuscript submissions: closed (20 April 2013)
Prof. Dr. Jack A. Schalken
Research Director Urology, Dept. of Urology, University Hospital Nijmegen, Box 9101, Nijmegen NL-6500 HB, The Netherlands
Interests: molecular and cellbiology of oncological diseases; cadherine mediated interactions and signal transductions; molecular diagnostics; urogenital oncology; veterinary oncology
The unmet needs in prostate cancer diagnosis and therapy are diverse; there is an urgent need for biomarkers that can be used for the early diagnosis of patients with clinically significant prostate cancer. Significant steps forward are made and are reviewed in this issue. Once metastasized, there is still no effective treatment, let stand alone a curative therapy. A better understanding of sustained androgen receptor signaling in CRPC has now led to more effective therapies. Apart from a better insight in the molecular aspects of prostate carcinogenesis and -progression, we need to understand the tumor cell biology. Identification of cancer initiating cells and therapies targeted to eradicate these population(s) are the way forward to combat this disease.
Prof. Dr. Jack A. Schalken
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed Open Access monthly journal published by MDPI.
- biomarkers (diagnostic prognostic and predictive)
- androgen receptor targeted therapy
- novel targets for therapy
- cancer initiating cells
Article: Alteration of Podocyte Protein Expression and Localization in the Early Stage of Various Hemodynamic Conditions
Int. J. Mol. Sci. 2013, 14(3), 5998-6011; doi:10.3390/ijms14035998
Received: 18 January 2013; in revised form: 3 March 2013 / Accepted: 5 March 2013 / Published: 15 March 2013| Download PDF Full-text (4329 KB) | Download XML Full-text
Article: Plasma miRNAs as Biomarkers to Identify Patients with Castration-Resistant Metastatic Prostate Cancer
Int. J. Mol. Sci. 2013, 14(4), 7757-7770; doi:10.3390/ijms14047757
Received: 16 February 2013; in revised form: 20 March 2013 / Accepted: 22 March 2013 / Published: 10 April 2013| Download PDF Full-text (681 KB) | Download XML Full-text |
Int. J. Mol. Sci. 2013, 14(5), 8832-8840; doi:10.3390/ijms14058832
Received: 21 February 2013; in revised form: 21 March 2013 / Accepted: 8 April 2013 / Published: 24 April 2013| Download PDF Full-text (200 KB)
Article: D-pinitol Inhibits Prostate Cancer Metastasis through Inhibition of αVβ3 Integrin by Modulating FAK, c-Src and NF-κB Pathways
Int. J. Mol. Sci. 2013, 14(5), 9790-9802; doi:10.3390/ijms14059790
Received: 29 March 2013; in revised form: 26 April 2013 / Accepted: 2 May 2013 / Published: 8 May 2013| Download PDF Full-text (1118 KB)
Int. J. Mol. Sci. 2013, 14(5), 10438-10464; doi:10.3390/ijms140510438
Received: 15 April 2013; in revised form: 8 May 2013 / Accepted: 8 May 2013 / Published: 21 May 2013| Download PDF Full-text (582 KB)
Article: Inhibition of CCL2 Signaling in Combination with Docetaxel Treatment Has Profound Inhibitory Effects on Prostate Cancer Growth in Bone
Int. J. Mol. Sci. 2013, 14(5), 10483-10496; doi:10.3390/ijms140510483
Received: 16 February 2013; in revised form: 14 March 2013 / Accepted: 6 May 2013 / Published: 21 May 2013| Download PDF Full-text (951 KB)
Last update: 30 October 2012