Special Issue "Molecular Research in Urology 2014"
Deadline for manuscript submissions: closed (15 June 2014)
Prof. Dr. Jack A. Schalken
Research Director Urology, Dept. of Urology, University Hospital Nijmegen, Box 9101, Nijmegen NL-6500 HB, The Netherlands
Interests: molecular and cellbiology of oncological diseases; cadherine mediated interactions and signal transductions; molecular diagnostics; urogenital oncology; veterinary oncology
Dr. Nees Matthias
Medical Biotechnology Knowledge Centre, VTT Technical Research Centre of Finland, Turku, Finland
The unmet needs in prostate cancer diagnosis and therapy are diverse; there is an urgent need for biomarkers that can be used for the early diagnosis of patients with clinically significant prostate cancer. Significant steps forward have been made and are reviewed in this issue. Once metastasized, there is still no effective treatment, nor stand alone a curative therapy. However, an improved understanding of sustained androgen receptor signaling in CRPC has now led to more effective therapies. Apart from a better insight in the molecular aspects of prostate carcinogenesis and progression, we need to understand tumor cell biology. Identification of cancer initiating cells and therapies targeted to eradicate these population(s) are the way forward to combat this disease.
You may also be interested in the closed special issue "Molecular Research in Urology" (http://www.mdpi.com/journal/ijms/special_issues/mol_res_uro) (38 papers published).
Prof. Dr. Jack A. Schalken
Dr. Nees Matthias
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed Open Access monthly journal published by MDPI.
- biomarkers (diagnostic prognostic and predictive)
- androgen receptor targeted therapy
- novel targets for therapy
- cancer initiating cells
Article: Comparative Evaluation of Urinary PCA3 and TMPRSS2: ERG Scores and Serum PHI in Predicting Prostate Cancer Aggressiveness
Int. J. Mol. Sci. 2014, 15(8), 13299-13316; doi:10.3390/ijms150813299
Received: 20 June 2014; in revised form: 15 July 2014 / Accepted: 18 July 2014 / Published: 30 July 2014| PDF Full-text (731 KB)
Article: Potential Spermatogenesis Recovery with Bone Marrow Mesenchymal Stem Cells in an Azoospermic Rat Model
Int. J. Mol. Sci. 2014, 15(8), 13151-13165; doi:10.3390/ijms150813151
Received: 15 June 2014; in revised form: 15 July 2014 / Accepted: 16 July 2014 / Published: 24 July 2014| PDF Full-text (4712 KB)
Review: Possible Prognostic and Therapeutic Significance of c-Kit Expression, Mast Cell Count and Microvessel Density in Renal Cell Carcinoma
Int. J. Mol. Sci. 2014, 15(7), 13060-13076; doi:10.3390/ijms150713060
Received: 28 May 2014; in revised form: 17 July 2014 / Accepted: 17 July 2014 / Published: 23 July 2014| PDF Full-text (897 KB)
Article: Copy Number Analysis of 24 Oncogenes: MDM4 Identified as a Putative Marker for Low Recurrence Risk in Non Muscle Invasive Bladder Cancer
Int. J. Mol. Sci. 2014, 15(7), 12458-12468; doi:10.3390/ijms150712458
Received: 25 March 2014; in revised form: 26 June 2014 / Accepted: 4 July 2014 / Published: 14 July 2014| PDF Full-text (745 KB)
Article: Protein Tyrosine Kinase 7 (PTK7) as a Predictor of Lymph Node Metastases and a Novel Prognostic Biomarker in Patients with Prostate Cancer
Int. J. Mol. Sci. 2014, 15(7), 11665-11677; doi:10.3390/ijms150711665
Received: 27 April 2014; in revised form: 28 May 2014 / Accepted: 12 June 2014 / Published: 1 July 2014| PDF Full-text (1041 KB)
Article: PSMA, EpCAM, VEGF and GRPR as Imaging Targets in Locally Recurrent Prostate Cancer after Radiotherapy
Int. J. Mol. Sci. 2014, 15(4), 6046-6061; doi:10.3390/ijms15046046
Received: 24 January 2014; in revised form: 28 March 2014 / Accepted: 28 March 2014 / Published: 10 April 2014| PDF Full-text (1557 KB) | HTML Full-text | XML Full-text
Article: Evodiamine Induces Apoptosis and Enhances TRAIL-Induced Apoptosis in Human Bladder Cancer Cells through mTOR/S6K1-Mediated Downregulation of Mcl-1
Int. J. Mol. Sci. 2014, 15(2), 3154-3171; doi:10.3390/ijms15023154
Received: 27 December 2013; in revised form: 13 February 2014 / Accepted: 14 February 2014 / Published: 21 February 2014| PDF Full-text (1761 KB) | HTML Full-text | XML Full-text
Last update: 25 February 2014