Special Issue "Molecular Research in Urology 2014"


A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology".

Deadline for manuscript submissions: closed (15 June 2014)

Special Issue Editors

Guest Editor
Prof. Dr. Jack A. Schalken
Research Director Urology, Dept. of Urology, University Hospital Nijmegen, Box 9101, Nijmegen NL-6500 HB, The Netherlands
Website: http://www.narcis.nl/person/RecordID/PRS1239673/Language/en
E-Mail: j.schalken@uro.umcn.nl
Interests: molecular and cellbiology of oncological diseases; cadherine mediated interactions and signal transductions; molecular diagnostics; urogenital oncology; veterinary oncology

Guest Editor
Dr. Nees Matthias
Medical Biotechnology Knowledge Centre, VTT Technical Research Centre of Finland, Turku, Finland
Website: http://tgsb.vtt.fi/kallioniemi%20group.htm
E-Mail: Matthias.Nees@vtt.fi

Special Issue Information

Dear Colleagues,

The unmet needs in prostate cancer diagnosis and therapy are diverse; there is an urgent need for biomarkers that can be used for the early diagnosis of patients with clinically significant prostate cancer. Significant steps forward have been made and are reviewed in this issue. Once metastasized, there is still no effective treatment, nor stand alone a curative therapy. However, an improved understanding of sustained androgen receptor signaling in CRPC has now led to more effective therapies. Apart from a better insight in the molecular aspects of prostate carcinogenesis and progression, we need to understand tumor cell biology. Identification of cancer initiating cells and therapies targeted to eradicate these population(s) are the way forward to combat this disease.

You may also be interested in the closed special issue "Molecular Research in Urology" (http://www.mdpi.com/journal/ijms/special_issues/mol_res_uro) (38 papers published).

Prof. Dr. Jack A. Schalken
Dr. Nees Matthias
Guest Editors


Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

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  • biomarkers (diagnostic prognostic and predictive)
  • androgen receptor targeted therapy
  • novel targets for therapy
  • cancer initiating cells

Published Papers (6 papers)

Int. J. Mol. Sci. 2014, 15(8), 13151-13165; doi:10.3390/ijms150813151
Received: 15 June 2014; in revised form: 15 July 2014 / Accepted: 16 July 2014 / Published: 24 July 2014
Show/Hide Abstract | PDF Full-text (4712 KB)
abstract graphic

Int. J. Mol. Sci. 2014, 15(7), 13060-13076; doi:10.3390/ijms150713060
Received: 28 May 2014; in revised form: 17 July 2014 / Accepted: 17 July 2014 / Published: 23 July 2014
Show/Hide Abstract | PDF Full-text (897 KB)

Int. J. Mol. Sci. 2014, 15(7), 12458-12468; doi:10.3390/ijms150712458
Received: 25 March 2014; in revised form: 26 June 2014 / Accepted: 4 July 2014 / Published: 14 July 2014
Show/Hide Abstract | PDF Full-text (745 KB)

Int. J. Mol. Sci. 2014, 15(7), 11665-11677; doi:10.3390/ijms150711665
Received: 27 April 2014; in revised form: 28 May 2014 / Accepted: 12 June 2014 / Published: 1 July 2014
Show/Hide Abstract | PDF Full-text (1041 KB)

Int. J. Mol. Sci. 2014, 15(4), 6046-6061; doi:10.3390/ijms15046046
Received: 24 January 2014; in revised form: 28 March 2014 / Accepted: 28 March 2014 / Published: 10 April 2014
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Int. J. Mol. Sci. 2014, 15(2), 3154-3171; doi:10.3390/ijms15023154
Received: 27 December 2013; in revised form: 13 February 2014 / Accepted: 14 February 2014 / Published: 21 February 2014
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Last update: 25 February 2014

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