Special Issue "Molecular Research in Urology 2014"
Deadline for manuscript submissions: closed (15 June 2014)
Prof. Dr. Jack A. Schalken (Website)
Research Director Urology, Dept. of Urology, University Hospital Nijmegen, Box 9101, Nijmegen NL-6500 HB, The Netherlands
Interests: molecular and cellbiology of oncological diseases; cadherine mediated interactions and signal transductions; molecular diagnostics; urogenital oncology; veterinary oncology
Dr. Nees Matthias (Website)
Medical Biotechnology Knowledge Centre, VTT Technical Research Centre of Finland, Turku, Finland
Phone: +358 40 8314 839
The unmet needs in prostate cancer diagnosis and therapy are diverse; there is an urgent need for biomarkers that can be used for the early diagnosis of patients with clinically significant prostate cancer. Significant steps forward have been made and are reviewed in this issue. Once metastasized, there is still no effective treatment, nor stand alone a curative therapy. However, an improved understanding of sustained androgen receptor signaling in CRPC has now led to more effective therapies. Apart from a better insight in the molecular aspects of prostate carcinogenesis and progression, we need to understand tumor cell biology. Identification of cancer initiating cells and therapies targeted to eradicate these population(s) are the way forward to combat this disease.
Prof. Dr. Jack A. Schalken
Dr. Nees Matthias
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed Open Access monthly journal published by MDPI.
- biomarkers (diagnostic prognostic and predictive)
- androgen receptor targeted therapy
- novel targets for therapy
- cancer initiating cells