Topic Editors

Research Centre, Sainte-Justine University Health Center, Department of Nutrition, Université de Montréal, Montreal, QC H3T 1C5, Canada
Prof. Dr. Joya Chandra
Department of Pediatrics Research, Division of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA

Nutrition and Health During and After Childhood Cancer

Abstract submission deadline
30 September 2025
Manuscript submission deadline
15 December 2025
Viewed by
1913

Topic Information

Dear Colleagues,

While the cure rate for pediatric cancer now exceeds 80%, more than 60% of childhood cancer survivors will develop a chronic health condition in the long term, years after the end of treatment. These long-term side effects include a greater risk of heart disease, metabolic syndrome, dyslipidemia, and hypertension, as well as a lower cardiorespiratory fitness level. Since inactivity and unhealthy food habits contribute to health complications in this population, nutritional interventions during and after treatment could help prevent these problems. In addition to the impact on long-term health, children and adolescents will most likely suffer from debilitating side effects during the course of treatments. Many of these side effects involve the gastrointestinal system and can result in weight loss and malnutrition, poor clinical outcomes, and lesser tolerance to treatments and may significantly harm patients’ prognosis due to dose reductions and treatment interruptions. What is less known is that cancer treatments can also, in the acute phase, negatively impact the child’s cardiometabolic health, leading to obesity, dyslipidemia, hypertension, and insulin resistance. Given the unequivocal importance of diet in cardiometabolic health, nutritional aspects during and after cancer treatment need to be better addressed. As part of the following Topic, entitled “Nutrition and Health During and After Childhood Cancer’, we aim to address several topics related to nutrition during and after pediatric cancer including, but not limited to, the impact of weight and diet on response to treatment and malnutrition, the impact of treatments on food intake and behaviors, nutritional interventions, and diet in survivors of childhood cancer, and the impact of nutrition on cardiometabolic health during and after childhood cancer treatment.

Prof. Dr. Valérie Marcil
Prof. Dr. Joya Chandra
Topic Editors

Keywords

  • pediatric cancer
  • pediatric cancer survivors
  • nutrition
  • cardiometabolic health
  • nutritional intervention
  • diet

Participating Journals

Journal Name Impact Factor CiteScore Launched Year First Decision (median) APC
Cancers
cancers
4.5 8.0 2009 17.4 Days CHF 2900 Submit
Children
children
2.0 2.7 2014 14 Days CHF 2400 Submit
Nutrients
nutrients
4.8 9.2 2009 13.5 Days CHF 2900 Submit

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Published Papers (1 paper)

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24 pages, 1064 KiB  
Article
Impact of Early Nutritional Intervention During Cancer Treatment on Dietary Intakes and Cardiometabolic Health in Children and Adolescents
by Josianne Delorme, Andra Dima, Véronique Bélanger, Mélanie Napartuk, Isabelle Bouchard, Caroline Meloche, Daniel Curnier, Serge Sultan, Caroline Laverdière, Daniel Sinnett and Valérie Marcil
Cancers 2025, 17(1), 157; https://doi.org/10.3390/cancers17010157 - 6 Jan 2025
Viewed by 1278
Abstract
Background/Objectives: Pediatric cancer survivors are at greater risk of cardiometabolic complications than their peers. This study evaluates the preliminary impact of the VIE (Valorization, Implication, Education) intervention, which integrates nutrition, physical activity, and psychological support, on dietary intake and cardiometabolic health among children [...] Read more.
Background/Objectives: Pediatric cancer survivors are at greater risk of cardiometabolic complications than their peers. This study evaluates the preliminary impact of the VIE (Valorization, Implication, Education) intervention, which integrates nutrition, physical activity, and psychological support, on dietary intake and cardiometabolic health among children and adolescents during cancer treatment. Methods: This comparative study includes pediatric cancer patients recruited to either the VIE intervention group or a control group receiving standard care. Post-treatment data on dietary intake, anthropometric measures, blood pressure, and biochemical parameters were compared between groups and stratified by level of involvement in the nutritional intervention and age at diagnosis (children and adolescents). Results: In the intervention group, 45 participants were included (51.1% male, mean age at evaluation 10.2 ± 4.5 years, mean time since end of treatment of 1.3 ± 0.8 years), and the control group comprised 77 participants (44.2% male, mean age at evaluation 12.0 ± 5.6 years, mean time since end of treatment of 1.4 ± 0.8 years). The intervention group had lower total caloric intake (mean: 1759 ± 513 vs. 1997 ± 669 kcal, p = 0.042) and higher calcium intake (mean: 567 ± 240 vs. 432 ± 197 mg/1000 kcal, p = 0.001). The participants who were highly involved in the nutritional intervention had greater protein-derived energy intake than the controls (mean: 17 ± 5 vs. 15 ± 4%, p = 0.029). While there was a tendency for a lesser proportion of cardiometabolic risk factors in the adolescents from the intervention group, the differences did not reach statistical significance. Conclusions: The VIE intervention improved some specific dietary intakes in the medium term after treatment completion but did not significantly impact cardiometabolic health outcomes. Additional strategies are needed to improve the diet of pediatric cancer patients, and further research is warranted to assess the long-term impact of such interventions. Full article
(This article belongs to the Topic Nutrition and Health During and After Childhood Cancer)
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