Comprehensive Advances and Clinical Practice in Neonatology

Topic Information

Dear Colleagues,

The management of critically ill neonates and pediatric patients remains one of the most complex and demanding areas in modern medicine. This complexity arises from the distinct physiological and developmental characteristics of children, which differ substantially from those of adults, necessitating specialized approaches to diagnosis, monitoring, and treatment. Optimal care for these patients relies on a coordinated multidisciplinary team that reflects the breadth and diversity of neonatal and pediatric pathology.

This Topic aims to provide a comprehensive overview of recent advances, emerging research, and current clinical practices in neonatology and the management of critically ill pediatric patients. We welcome original research articles, systematic and narrative reviews, as well as well-documented case reports addressing, but not limited to, the following key areas:

• Molecular basis of neonatal diseases: Emphasizing gene expression profiles, cellular signaling networks, and biomarker discovery to enhance understanding of disease pathogenesis, facilitate early diagnosis, and support the development of targeted therapeutic strategies.
• Obstetric and Neonatal Trauma: Effective management requires a thorough understanding of neonatal anatomy and pathophysiology. Early assessment, resuscitation, and ongoing care are best achieved through collaboration among neonatologists, obstetricians, pediatric surgeons, intensivists, and radiologists.
• Severe Neonatal Conditions: Disorders such as neonatal acute respiratory distress syndrome and necrotizing enterocolitis are associated with significant morbidity and mortality. Recent efforts to establish pediatric-specific diagnostic criteria and treatment protocols highlight the need for continued research. Management often necessitates advanced respiratory support and intensive care, involving multidisciplinary expertise.
• Congenital Malformations: This broad and complex field frequently intersects with genetic abnormalities, prematurity, and low birth weight. Prolonged hospitalization in neonatal intensive care units increases the risk of complications, including neonatal sepsis, underscoring the importance of integrated, team-based care.
• Care of Preterm and Low-Birth-Weight Infants: The multimodal management of these vulnerable patients requires substantial medical, technological, and economic resources. Advances in neonatal intensive care continue to improve survival, yet long-term outcomes remain an area of active investigation.

Through this Topic, we invite contributions from clinicians, researchers, and specialists across obstetrics, neonatology, pediatric disciplines, and related fields. Our goal is to foster interdisciplinary dialog and disseminate high-quality evidence that advances the understanding and clinical management of severe conditions in neonates and children.

Prof. Dr. Giovanni Vento
Dr. Elena Tarca
Topic Editors

Keywords

Participating Journals

Journal Name	Impact Factor	CiteScore	Launched Year	First Decision (median)	APC
Children children	2.6	4.5	2014	15.4 Days	CHF 2400	Submit
Diagnostics diagnostics	3.8	6.9	2011	20.4 Days	CHF 2600	Submit
Inflammation Journal inflammj	-	-	2026	15.0 days *	CHF 1000	Submit
International Journal of Molecular Sciences ijms	5.6	10.0	2000	17.5 Days	CHF 2900	Submit
Pediatric Reports pediatrrep	1.9	2.4	2009	16.7 Days	CHF 1600	Submit

* Median value for all MDPI journals in the first half of 2026.

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