Applications of Immunohistochemical Staining in Brain Diseases

Dear Colleagues,

Immunohistochemical staining (IHC) can be used to qualitatively or quantitatively recognize analytes involving peptides, proteins, or small molecules. The IHC technique can link to molecular imaging, bioinformatics analysis, artificial intelligence (AI)-based methods, therapeutic targeting with brain therapy, and basic research in brain diseases. Advances in IHC-related applications enable early detection and precise treatment in disease management. This Topic aims to apply cutting-edge research into multidisciplinary frontier viewpoints to various novelty concerns and provide insights into clinical issues underlying recent advances in aspects of disease treatment. Authors are invited to submit both reviews and original articles to our Topic collection. Potential subject include, but are not limited to:

1. Biomarkers or risk factors involving neuroinflammation or mitochondrial function in cell-to-animal innovative research of disease;
2. Diagnostic strategies targeting various brain diseases;
3. Molecular imaging that can reflect or predict disease development;
4. Bench-to-bedside applications to disease diagnosis, treatment, and clinical outcome, including IHC-based molecular or pharmacological interventions;
5. Biocybernetics and big data processing of large databases and genomics interactions using bioinformatics approaches;
6. Label the biomarkers for targeting brain diseases.

Prof. Dr. Andrew Chih Wei Huang
Dr. Bai Chuang Shyu
Prof. Dr. Seong Soo A. An
Dr. Anna Kozłowska
Topic Editors