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Keywords = water block release

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19 pages, 1940 KiB  
Article
Linkages Between Sorghum bicolor Root System Architectural Traits and Grain Yield Performance Under Combined Drought and Heat Stress Conditions
by Alec Magaisa, Elizabeth Ngadze, Tshifhiwa P. Mamphogoro, Martin P. Moyo and Casper N. Kamutando
Agronomy 2025, 15(8), 1815; https://doi.org/10.3390/agronomy15081815 - 26 Jul 2025
Viewed by 303
Abstract
Breeding programs often overlook the use of root traits. Therefore, we investigated the relevance of sorghum root traits in explaining its adaptation to combined drought and heat stress (CDHS). Six (i.e., three pre-release lines + three checks) sorghum genotypes were established at two [...] Read more.
Breeding programs often overlook the use of root traits. Therefore, we investigated the relevance of sorghum root traits in explaining its adaptation to combined drought and heat stress (CDHS). Six (i.e., three pre-release lines + three checks) sorghum genotypes were established at two low-altitude (i.e., <600 masl) locations with a long-term history of averagely very high temperatures in the beginning of the summer season, under two management (i.e., CDHS and well-watered (WW)) regimes. At each location, the genotypes were laid out in the field using a randomized complete block design (RCBD) replicated two times. Root trait data, namely root diameter (RD), number of roots (NR), number of root tips (NRT), total root length (TRL), root depth (RDP), root width (RW), width–depth ratio (WDR), root network area (RNA), root solidity (RS), lower root area (LRA), root perimeter (RP), root volume (RV), surface area (SA), root holes (RH) and root angle (RA) were gathered using the RhizoVision Explorer software during the pre- and post-flowering stage of growth. RSA traits differentially showed significant (p < 0.05) correlations with grain yield (GY) at pre- and post-flowering growth stages and under CDHS and WW conditions also revealing genotypic variation estimates exceeding 50% for all the traits. Regression models varied between pre-flowering (p = 0.013, R2 = 47.15%, R2 Predicted = 29.32%) and post-flowering (p = 0.000, R2 = 85.64%, R2 Predicted = 73.30%) growth stages, indicating post-flowering as the optimal stage to relate root traits to yield performance. RD contributed most to the regression model at post-flowering, explaining 51.79% of the 85.64% total variation. The Smith–Hazel index identified ICSV111IN and ASAREACA12-3-1 as superior pre-release lines, suitable for commercialization as new varieties. The study demonstrated that root traits (in particular, RD, RW, and RP) are linked to crop performance under CDHS conditions and should be incorporated in breeding programs. This approach may accelerate genetic gains not only in sorghum breeding programs, but for other crops, while offering a nature-based breeding strategy for stress adaptation in crops. Full article
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14 pages, 1410 KiB  
Article
Uptake, Distribution, and Activity of Pluronic F68 Adjuvant in Wheat and Its Endophytic Bacillus Isolate
by Anthony Cartwright, Mohammad Zargaran, Anagha Wankhade, Astrid Jacobson, Joan E. McLean, Anne J. Anderson and David W. Britt
Agrochemicals 2025, 4(3), 12; https://doi.org/10.3390/agrochemicals4030012 - 23 Jul 2025
Viewed by 260
Abstract
Surfactants are widely utilized in agriculture as emulsifying, dispersing, anti-foaming, and wetting agents. In these adjuvant roles, the inherent biological activity of the surfactant is secondary to the active ingredients. Here, the hydrophilic non-ionic surface-active tri-block copolymer Pluronic® F68 is investigated for [...] Read more.
Surfactants are widely utilized in agriculture as emulsifying, dispersing, anti-foaming, and wetting agents. In these adjuvant roles, the inherent biological activity of the surfactant is secondary to the active ingredients. Here, the hydrophilic non-ionic surface-active tri-block copolymer Pluronic® F68 is investigated for direct biological activity in wheat. F68 binds to and inserts into lipid membranes, which may benefit crops under abiotic stress. F68’s interactions with Triticum aestivum (var Juniper) seedlings and a seed-borne Bacillus spp. endophyte are presented. At concentrations below 10 g/L, F68-primed wheat seeds exhibited unchanged emergence. Root-applied fluorescein-F68 (fF68) was internalized in root epidermal cells and concentrated in highly mobile endosomes. The potential benefit of F68 in droughted wheat was examined and contrasted with wheat treated with the osmolyte, glycine betaine (GB). Photosystem II activity of droughted plants dropped significantly below non-droughted controls, and no clear benefit of F68 (or GB) during drought or rehydration was observed. However, F68-treated wheat exhibited increased transpiration values (for watered plants only) and enhanced shoot dry mass (for watered and droughted plants), not observed for GB-treated or untreated plants. The release of seed-borne bacterial endophytes into the spermosphere of germinating seeds was not affected by F68 (for F68-primed seeds as well as F68 applied to roots), and the planktonic growth of a purified Bacillus spp. seed endophyte was not reduced by F68 applied below the critical micelle concentration. These studies demonstrated that F68 entered wheat root cells, concentrated in endosomes involved in transport, significantly promoted shoot growth, and showed no adverse effects to plant-associated bacteria. Full article
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15 pages, 3688 KiB  
Article
External Barrier and Internal Attack: Synergistic Effect of Microcapsule Fire Extinguishing Agent and Fine Water Mist on Suppressing Lithium-Ion Battery Fire
by Xiangjian Wang, Zhanwen He, Jianjun Gao, Yibo Guo, Haijun Zhang and Mingchao Wang
Materials 2025, 18(13), 3082; https://doi.org/10.3390/ma18133082 - 29 Jun 2025
Viewed by 402
Abstract
When lithium-ion batteries experience thermal runaway, a large amount of heat rapidly accumulates inside, causing the internal pressure to rise sharply. Once the pressure exceeds the battery’s safety valve design capacity, the valve activates and releases flammable gas. If ignited in a high-temperature [...] Read more.
When lithium-ion batteries experience thermal runaway, a large amount of heat rapidly accumulates inside, causing the internal pressure to rise sharply. Once the pressure exceeds the battery’s safety valve design capacity, the valve activates and releases flammable gas. If ignited in a high-temperature environment, the escaping gas can cause a jet fire containing high-temperature substances. Effectively controlling the internal temperature of the jet fire, especially rapidly cooling the core area of the flame during the jet process, is important to prevent the spread of lithium-ion battery fires. Therefore, this work proposes a strategy of a synergistic effect using microcapsule fire extinguishing agents and fine water mist to achieve an external barrier and an internal attack. The microcapsule fire extinguishing agents are prepared by using melamine–urea–formaldehyde resin as the shell and 1,1,1,2,2,3,3,4,4-nonafluoro-4-methoxybutane (C5H3F9O) and 1,1,2,2,3,3,4-heptafluorocyclopentane (C5H3F7) as the composite core. During the process of lithium-ion battery thermal runaway, the microcapsule fire extinguishing agents can enter the inner area of the jet fire under the protection of the fine water mist. The microcapsule shell ruptures at 100 °C, releasing the highly effective composite fire suppressant core inside the jet fire. The fine water mist significantly blocks the transfer of thermal radiation, inhibiting the spread of the fire. Compared to the suppression with fine water mist only, the time required to reduce the battery temperature from the peak value to a low temperature is reduced by 66 s and the peak temperature of the high-temperature substances above the battery is reduced by 228.2 °C. The propagation of the thermal runaway is suppressed, and no thermal runaway of other batteries around the faulty unit will occur. This synergistic suppression strategy of fine water mist and microcapsule fire extinguishing agent (FWM@M) effectively reduces the adverse effects of jet fires on the propagation of thermal runaway (TR) of lithium-ion batteries, providing a new solution for efficiently extinguishing lithium-ion battery fires. Full article
(This article belongs to the Section Advanced and Functional Ceramics and Glasses)
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28 pages, 3006 KiB  
Article
Self-Assembling Amphiphilic ABA Triblock Copolymers of Hyperbranched Polyglycerol with Poly(tetrahydrofuran) and Their Nanomicelles as Highly Efficient Solubilization and Delivery Systems of Curcumin
by Dóra Fecske, György Kasza, Gergő Gyulai, Kata Horváti, Márk Szabó, András Wacha, Zoltán Varga, Györgyi Szarka, Yi Thomann, Ralf Thomann, Rolf Mülhaupt, Éva Kiss, Attila Domján, Szilvia Bősze, Laura Bereczki and Béla Iván
Int. J. Mol. Sci. 2025, 26(12), 5866; https://doi.org/10.3390/ijms26125866 - 19 Jun 2025
Viewed by 632
Abstract
Delivering of hydrophobic drugs by polymeric nanoparticles is an intensively investigated research and development field worldwide due to the insufficient solubility of many existing and potential new drugs in aqueous media. Among polymeric nanoparticles, micelles of biocompatible amphiphilic block copolymers are among the [...] Read more.
Delivering of hydrophobic drugs by polymeric nanoparticles is an intensively investigated research and development field worldwide due to the insufficient solubility of many existing and potential new drugs in aqueous media. Among polymeric nanoparticles, micelles of biocompatible amphiphilic block copolymers are among the most promising candidates for solubilization, encapsulation, and delivery of hydrophobic drugs to improve the water solubility and thus the bioavailability of such drugs. In this study, amphiphilic ABA triblock copolymers containing biocompatible hydrophilic hyperbranched (dendritic) polyglycerol (HbPG) outer and hydrophobic poly(tetrahydrofuran) (PTHF) inner segments were synthesized using amine-telechelic PTHF as a macroinitiator for glycidol polymerization. These hyperbranched–linear–hyperbranched block copolymers form nanosized micelles with 15–20 nm diameter above the critical micelle concentration. Coagulation experiments proved high colloidal stability of the aqueous micellar solutions of these block copolymers against temperature changes. The applicability of block copolymers as drug delivery systems was investigated using curcumin, a highly hydrophobic, water-insoluble, natural anti-cancer agent. High and efficient drug solubilization up to more than 3 orders of magnitude to that of the water solubility of curcumin (>1500-fold) is achieved with the HbPG-PTHF-HbPG block copolymer nanomicelles, locating the drug in amorphous form in the inner PTHF core. Outstanding stability of and sustained curcumin release from the drug-loaded block copolymer micelles were observed. The in vitro bioactivity of the curcumin-loaded nanomicelles was investigated on U-87 glioblastoma cell line, and an optimal triblock copolymer composition was found, which showed highly effective cellular uptake and no toxicity. These findings indicate that the HbPG-PTHF-HbPG triblock copolymers are promising candidates for advanced drug solubilization and delivery systems. Full article
(This article belongs to the Special Issue Design, Synthesis and Applications of Dendrimer Materials)
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16 pages, 3741 KiB  
Article
Mechanical Properties of Large-Volume Waste Concrete Lumps Cemented by Desert Mortar: Laboratory Tests
by Hui Chen, Zhiyuan Qi, Baiyun Yu and Xinyu Li
Buildings 2025, 15(12), 2060; https://doi.org/10.3390/buildings15122060 - 15 Jun 2025
Viewed by 456
Abstract
In response to the high cost and environmental impact of backfill materials in Xinjiang mines, an eco-friendly, large-volume composite was developed by bonding desert-sand mortar to waste concrete. A rock-filled concrete process produced a highly flowable mortar from desert sand, cement, and fly [...] Read more.
In response to the high cost and environmental impact of backfill materials in Xinjiang mines, an eco-friendly, large-volume composite was developed by bonding desert-sand mortar to waste concrete. A rock-filled concrete process produced a highly flowable mortar from desert sand, cement, and fly ash. Waste concrete blocks served as coarse aggregate. Specimens were cured for 28 days, then subjected to uniaxial compression tests on a mining rock-mechanics system using water-to-binder ratios of 0.30, 0.35, and 0.40 and aggregate sizes of 30–40 mm, 40–50 mm, and 50–60 mm. Mechanical performance—failure modes, stress–strain response, and related properties—was systematically evaluated. Crack propagation was tracked via digital image correlation (DIC) and acoustic emission (AE) techniques. Failure patterns indicated that the pure-mortar specimens exhibited classic brittle fractures with through-going cracks. Aggregate-containing specimens showed mixed-mode failure, with cracks flowing around aggregates and secondary branches forming non-through-going damage networks. Optimization identified a 0.30 water-to-binder ratio (Groups 3 and 6) as optimal, yielding an average strength of 25 MPa. Among the aggregate sizes, 40–50 mm (Group 7) performed best, with 22.58 MPa. The AE data revealed a three-stage evolution—linear-elastic, nonlinear crack growth, and critical failure—with signal density positively correlating to fracture energy. DIC maps showed unidirectional energy release in pure-mortar specimens, whereas aggregate-containing specimens displayed chaotic energy patterns. This confirms that aggregates alter stress fields at crack tips and redirect energy-dissipation paths, shifting failure from single-crack propagation to a multi-scale damage network. These results provide a theoretical basis and technical support for the resource-efficient use of mining waste and advance green backfill technology, thereby contributing to the sustainable development of mining operations. Full article
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24 pages, 3511 KiB  
Article
Dynamics of Greenhouse Gas Fluxes in Açaí Cultivation: Comparing Amazonian Upland and Floodplain Soils
by Mario Flores Aroni, José Henrique Cattanio and Claudio José Reis de Carvalho
Forests 2025, 16(6), 944; https://doi.org/10.3390/f16060944 - 4 Jun 2025
Viewed by 1363
Abstract
Global warming is driven by the increasing atmospheric emissions of greenhouse gases. Soils are highly sensitive to climate change and can shift from being carbon reservoirs to carbon sources under warmer and wetter conditions. This study is the first to simultaneously measure trace [...] Read more.
Global warming is driven by the increasing atmospheric emissions of greenhouse gases. Soils are highly sensitive to climate change and can shift from being carbon reservoirs to carbon sources under warmer and wetter conditions. This study is the first to simultaneously measure trace gas fluxes in Euterpe oleracea (açaí) plantations in upland areas, contrasting them with floodplain areas managed for açaí production in the eastern Amazon. Flux measurements were conducted during both the rainy and dry seasons using the closed dynamic chamber technique. In upland areas, CO2 fluxes exhibited spatial (plateau vs. lowland) and temporal (hourly, daily, and seasonal) variations. During both the rainy and dry months, CH4 uptake in upland soils was higher in lowland areas compared to the plateau. When comparing the two ecosystems, upland areas emitted more CO2 during the rainy season, while floodplain areas released more CH4 into the atmosphere. Unexpectedly, during the dry season, floodplain soils produced more CO2 and captured more CH4 from the atmosphere compared to upland soils. In upland areas, CO2-equivalent production reached 59.1 Mg CO2-eq ha−1 yr−1, while in floodplain areas, it reached 49.3 Mg CO2-eq ha−1 yr−1. Soil organic matter plays a vital role in preserving water and microorganisms, enhancing ecosystem productivity in uniform açaí plantations and intensifying the transfer of CH4 from the atmosphere to the soil. However, excessive soil moisture can create anoxic conditions, block gas diffusion, reduce soil respiration, and potentially turn the soil from a sink into a source of CH4. Full article
(This article belongs to the Special Issue Forest Dynamics Under Climate and Land Use Change)
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19 pages, 7450 KiB  
Article
Carbon Dots-Enhanced Soy Protein Isolate/Polyvinyl Alcohol Composite Film for Active Preservation of Oxidation-Sensitive Foods
by Linlin Zhao, Huinan Jiang, Zhengxuan Han, Wenqin Gu, Bimal Chitrakar and Xiangren Meng
Antioxidants 2025, 14(6), 669; https://doi.org/10.3390/antiox14060669 - 31 May 2025
Viewed by 655
Abstract
Carbon dots perform a variety of functions when they are incorporated into active films synthesized from soy protein isolate/polyvinyl alcohol. The study examined the impact of varying concentrations of carbon dots on the structural, bioactive, and physicochemical properties of composite films. The addition [...] Read more.
Carbon dots perform a variety of functions when they are incorporated into active films synthesized from soy protein isolate/polyvinyl alcohol. The study examined the impact of varying concentrations of carbon dots on the structural, bioactive, and physicochemical properties of composite films. The addition of carbon dots improved the UV-blocking rate (up to 99.64%) with a higher water-barrier property of the films. The films with carbon dot-enhanced antioxidant activities (ABTS was 99.71%, and DPPH was 51.44%) exhibited strong antibacterial activities against Escherichia coli and Staphylococcus aureus. In a hydrophilic environment, the high release rate of carbon dots was found to enhance the biological activity of films. The application of 0.8% composite film resulted in significant shelf-life extension for fresh jujubes, meatballs, and soybean oil. These results demonstrated the feasibility of composite films as an active packaging material. Full article
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20 pages, 3725 KiB  
Article
Antioxidant Biocomposite Films Based on Grape Stalk Lignocellulosic Fractions and Biodegradable Polyesters
by Irene Maté, Lorena Atarés, Maria Vargas and Amparo Chiralt
Polymers 2025, 17(11), 1525; https://doi.org/10.3390/polym17111525 - 29 May 2025
Viewed by 511
Abstract
Grape stalk (GS) from winemaking is a waste rich in antioxidant compounds that can be valorized to obtain active food packaging materials. Biocomposite films of poly (butylene succinate) (PBS) and poly(3-hydroxybutyrate)-co-hydroxyvalerate (PHBV) with 10% of GS particles, previously submitted or not to subcritical [...] Read more.
Grape stalk (GS) from winemaking is a waste rich in antioxidant compounds that can be valorized to obtain active food packaging materials. Biocomposite films of poly (butylene succinate) (PBS) and poly(3-hydroxybutyrate)-co-hydroxyvalerate (PHBV) with 10% of GS particles, previously submitted or not to subcritical water extraction at 170 °C and 180 °C, were obtained by melt blending and characterized. The fibres were better integrated in the PHBV matrix than in PBS, while other molecular compounds from the fillers were released to the polymer matrix, allowing for their antioxidant action. Fillers promoted the stiffness of PBS films (11–44%), reducing their resistance to break and extensibility by 25%, without significant changes in polymer crystallinity or thermal stability. However, this reduced the crystallinity (13%) and thermal stability of PHBV films, decreasing their rigidity (55%). All fibres promoted the oxygen barrier capacity in composites (by about 20–35% for PBS and PHBV, respectively) while also providing them with UV light blocking effects. This barrier effect enhanced the ability of the films to preserve sunflower oil against oxidation, while in PHBV composites, the migration of antioxidant compounds was also detected. No remarkable differences in the effects of the different GS fillers on the properties of composites were detected. Full article
(This article belongs to the Section Biobased and Biodegradable Polymers)
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25 pages, 10258 KiB  
Article
Full-Scale Experimental Investigation of Temperature Distribution and Smoke Flow in a Road Tunnel with a Novel Water Mist Fire Fighting System
by Shouzhong Feng, Deyuan Kan and Chao Guo
Fire 2025, 8(6), 216; https://doi.org/10.3390/fire8060216 - 28 May 2025
Viewed by 641
Abstract
This study presents a novel water mist fire fighting system that integrates water mist sprays and water mist curtains, designed to achieve simultaneous fire suppression, thermal insulation, and smoke control. Three full-scale experiments were conducted under various fire scenarios, and the changes in [...] Read more.
This study presents a novel water mist fire fighting system that integrates water mist sprays and water mist curtains, designed to achieve simultaneous fire suppression, thermal insulation, and smoke control. Three full-scale experiments were conducted under various fire scenarios, and the changes in fire behavior and heat release rate were examined to evaluate the effectiveness of the water mist system in extinguishing fires. Additionally, the spatiotemporal changes in ceiling temperature were monitored to assess the cooling and protective effects of the water mist. The thermal insulation capability of the system was also investigated by detecting the temperature distribution inside the tunnel. Moreover, the smoke conditions upstream and downstream of the tunnel were analyzed to evaluate the smoke-blocking performance of the water mist system. The findings demonstrate that the water mist fire fighting system is highly efficient in attenuating the fire and restricting its progression. Within the water mist spray section, the average ceiling temperature decreased exponentially during both the initial and steady burning phases across all tested fire scenarios. Nonetheless, the smoke-carrying capacity of the water mist spray is limited. Fortunately, the dispersed smoke was diluted by water mist, markedly enhancing visibility and mitigating the impact of smoke on tunnel illumination. Full article
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19 pages, 6951 KiB  
Proceeding Paper
Numerical Analysis of Debris Impact Forces and Its Environmental Repercussions Using Smoothed Particle Hydrodynamics
by Muhammad Khairi A. Wahab, Mohd Remy Rozainy Mohd Arif Zainol, Mohamad Aizat Abas and Norizham Abdul Razak
Environ. Earth Sci. Proc. 2025, 33(1), 7; https://doi.org/10.3390/eesp2025033007 - 13 Mar 2025
Viewed by 442
Abstract
Debris flow is a destructive event occurring in elevated terrains, causing significant damage to the affected areas. It results in casualties and significant harm to the environment and society. Hence, a comprehensive evaluation is essential in order to prevent, mitigate, and increase knowledge [...] Read more.
Debris flow is a destructive event occurring in elevated terrains, causing significant damage to the affected areas. It results in casualties and significant harm to the environment and society. Hence, a comprehensive evaluation is essential in order to prevent, mitigate, and increase knowledge of the consequences of debris flows. This paper focuses on evaluating the impact of the deposition board. The methodology involved a simulation of two cases to demonstrate the debris flow based on the steepness of the flume slope at 25° angles with full and half openings at the gate. The limestone particles with a total volume of 1 × 103 m3 acted as debris and were released with water from the tank to the deposition board with an area of 1 m2. The force of particle distribution from the flume that hit the building block on the deposition board was determined. Based on the numerical results, the maximum force was about 55.2 N and 47.3 N for each fully open and half open gate, respectively. In actual situations, the maximum impact force (5520 N) can be 100 times greater compared to model values (55.2 N). Research indicates that pressures over 100 kPa cause damage to reinforced concrete structures. Debris flow can pose a substantial risk to the impacted area in real-life scenarios. This study is valuable for conducting risk assessments, creating guidelines, and reducing the likelihood of debris flows in high-risk areas. Full article
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19 pages, 5924 KiB  
Article
Integrated Single Superphosphate with Cattle Manure Increased Growth, Yield, and Phosphorus Availability of Maize (Zea mays L.) Under Rainfed Conditions
by Samraiz Ali and Abid Ali
Nitrogen 2025, 6(1), 9; https://doi.org/10.3390/nitrogen6010009 - 13 Feb 2025
Cited by 1 | Viewed by 1170
Abstract
Mostly, phosphorus (P) fertilizers are fixed in the interlayer of soil and become unavailable to crop plants. Combined inorganic fertilizers with organic manures could be a suitable solution to release these nutrients from the soil. P deficiency in soil adversely affected crop growth [...] Read more.
Mostly, phosphorus (P) fertilizers are fixed in the interlayer of soil and become unavailable to crop plants. Combined inorganic fertilizers with organic manures could be a suitable solution to release these nutrients from the soil. P deficiency in soil adversely affected crop growth and development to a larger extent. To check out this problem, present research was conducted over a two-year period to evaluate the efficiency of a combined mixture of inorganic P and organic manure as a better farming strategy, in relation to their sole treatments, for enhancing P availability, plant growth, yield and quality, and soil properties. The inorganic source of P was SSP in the form of P2O5, while the organic source was cattle manure mixed with crop residues called farmyard manure (FYM). The experiment consisted of the same six treatments over each year: (i) control (0F+0P), (ii) 45 kg P2O5 ha−1 (45P), (iii) 90 kg P2O5 ha−1 (90P), (iv) 45 kg P2O5 ha−1 + 1000 kg FYM ha−1 (45P+1000F), (v) 1000 kg FYM ha−1 (1000F), and (vi) 2000 kg FYM ha−1 (2000F), using randomized complete block design (RCBD), to five replications. Results demonstrated that the combination of SSP with FYM increased the plant height (27.9%), grain yield (23.4%), and plant P uptake efficiency (43.7%) of maize as compared to sole SSP at 90 kg P2O5 ha−1, which occurred due to improved P availability in soil. By comparing sole amendments of P fertilizer sources, FYM-treated plots have performed better in increasing maize growth and yield components such as plant height, dry matter, crop growth rate (CGR), net photosynthetic rate, grain yield, and crude protein (e.g., nitrogen contents); this happened due to enhanced soil chemical properties that might be related to improvement in P level and decreased bulk density of soil. Further, significant positive correlations were exhibited among studied crop and soil data. The plant available P and grain protein contents (N concentration) also showed a significant positive correlation and exhibited higher nitrogen contents under organic amendments of P fertilizer, as compared to inorganic treatments. The study concluded that combined SSP at 45 kg P2O5 ha−1 with organic cattle manure at 1000 kg ha−1 has a great potential for enhancing maize productivity under water deficit conditions. Results of this research may further be improved by including rigorous soil samples and field heterogeneity data between the plots and the years, which will provide more clear findings from a combined mixture of organic and inorganic fertilization. Full article
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21 pages, 23279 KiB  
Article
Effects of Microplastic Accumulation on Neuronal Death After Global Cerebral Ischemia
by Dong Yeon Kim, Min Kyu Park, Hyun Wook Yang, Seo Young Woo, Hyun Ho Jung, Dae-Soon Son, Bo Young Choi and Sang Won Suh
Cells 2025, 14(4), 241; https://doi.org/10.3390/cells14040241 - 7 Feb 2025
Cited by 2 | Viewed by 2291
Abstract
Brain ischemia, a condition in which the brain is deprived of blood flow, can lead to a stroke due to blocked or unstable blood vessels. Global cerebral ischemia (GCI), characterized by an interruption in blood flow, deprives the brain of oxygen and nutrients, [...] Read more.
Brain ischemia, a condition in which the brain is deprived of blood flow, can lead to a stroke due to blocked or unstable blood vessels. Global cerebral ischemia (GCI), characterized by an interruption in blood flow, deprives the brain of oxygen and nutrients, producing reactive oxygen species (ROS) that trigger cell death, which kills nerve cells. Microplastics (MPs), tiny environmental pollutants, can enter the human body through contaminated food, water, disposable items, cosmetics, and more. Once in the brain, MPs can increase neuroinflammation by overstimulating inflammatory factors such as microglia. MPs can also damage neurons by scratching myelin and microtubules, slowing signal transduction, causing cognitive impairment, and leading to neuronal death. Furthermore, microtubule damage may result in the release of phosphorylated tau proteins, potentially linked to Alzheimer’s disease. We hypothesized that MPs could exacerbate neuroinflammation and microtubule destruction after GCI, leading to increased neuronal death. To test this hypothesis, we administered MPs (0.5 µm) orally at a dose of 50 mg/kg before and after inducing GCI. Staining techniques such as Fluoro-Jade B (FJB), ionized calcium-binding adaptor molecule 1 (Iba-1), cluster of differentiation 68 (CD68), myelin basic protein (MBP), and microtubule-associated protein 2 (MAP2) were used, along with Western blot analysis for interleukin-6 (IL-6), TNF-α, tau-5, and phospho-tau (S396) to evaluate the effects of MPs on neuronal cell death, neuroinflammation, and microtubule destruction. The results showed that MP accumulation significantly increased neuroinflammation, microtubule disruption, and neuronal cell death in the GCI-MP group compared to the GCI-vehicle group. Therefore, this study suggests that MP accumulation in daily life may contribute to the exacerbation of the disease, potentially leading to severe neuronal cell death after GCI. Full article
(This article belongs to the Special Issue Cell Stress and Intervention in Neurological Disease)
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20 pages, 3293 KiB  
Article
Study of the Effects of Different Dielectric Environments on the Characteristics of Electro-Explosive Discharge of Metal Wires and Shock Waves
by Jiawei Liu, Jin Wang, Qilong Xue, Yuanyuan Zhang, Hufeng Li and Song Fang
Appl. Sci. 2025, 15(1), 218; https://doi.org/10.3390/app15010218 - 30 Dec 2024
Viewed by 762
Abstract
The electrical explosive fragmentation technique has attracted widespread attention due to its environmental friendliness and high efficiency. However, the mechanism by which dielectrics influence rock fragmentation remains unclear. This study innovatively selected seven types of environmentally friendly dielectrics to systematically investigate their roles [...] Read more.
The electrical explosive fragmentation technique has attracted widespread attention due to its environmental friendliness and high efficiency. However, the mechanism by which dielectrics influence rock fragmentation remains unclear. This study innovatively selected seven types of environmentally friendly dielectrics to systematically investigate their roles in the metallic wire electrical explosive rock fragmentation process. By precisely characterizing the crack morphology of concrete blocks, shock wave–strain responses, and discharge signal characteristics, the diverse mechanisms by which different dielectrics modulate rock fragmentation were revealed. The results indicate that oxide dielectrics release energy continuously through thermochemical reactions, highly conductive solutions accelerate energy deposition, and reductant suspensions generate strong secondary shock waves—all significantly outperforming tap water in terms of rock fragmentation performance. Notably, the energy deposition efficiency shows a nonlinear relationship with fragmentation effectiveness, influenced by factors such as energy release modes, dielectric composition, and bubble dynamics. The energy conversion mechanism of the electrical explosive rock fragmentation process studied in this paper provides a theoretical foundation for the fine-tuning, customization, and greening of electrical explosive rock fragmentation strategies in engineering practice. Full article
(This article belongs to the Section Civil Engineering)
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19 pages, 3298 KiB  
Article
Quantitative Characterization Method of Additional Resistance Based on Suspended Particle Migration and Deposition Model
by Huan Chen, Yanfeng Cao, Jifei Yu, Xiaopeng Zhai, Jianlin Peng, Wei Cheng, Tongchuan Hao, Xiaotong Zhang and Weitao Zhu
Energies 2024, 17(24), 6246; https://doi.org/10.3390/en17246246 - 11 Dec 2024
Viewed by 605
Abstract
The phenomenon of pore blockage caused by injected suspended particles significantly impacts the efficiency of water injection and production capacity release in offshore oilfields, leading to increased additional resistance during the injection process. To enhance water injection volumes in injection wells, it is [...] Read more.
The phenomenon of pore blockage caused by injected suspended particles significantly impacts the efficiency of water injection and production capacity release in offshore oilfields, leading to increased additional resistance during the injection process. To enhance water injection volumes in injection wells, it is essential to quantitatively study the additional resistance caused by suspended particle blockage during water injection. However, there is currently no model for calculating the additional resistance resulting from suspended particle blockage. Therefore, this study establishes a permeability decline model based on the microscopic dispersion kinetic equation of particle transport. The degree of blockage is characterized by the reduction in fluid volume, and the additional resistance caused by particle migration and blockage during water injection is quantified based on the fluid volume decline. This study reveals that over time, suspended particles do not continuously migrate deeper into the formation but tend to deposit near the wellbore, blocking pores and increasing additional resistance. Over time, the concentration of suspended particles near the wellbore approaches the initial concentration of the injected water. An increase in seepage velocity raises the peak concentration of suspended particles, but when the seepage velocity reaches a certain threshold, its effect on particle migration stabilizes. The blockage location of suspended particles near the wellbore is significantly influenced by seepage velocity and time. An increase in particle concentration and size accelerates blockage formation but does not change the blockage location. As injection time increases, the fitted injection volume and permeability exhibit a power-law decline. Based on the trend of injection volume reduction, the additional resistance caused by water injection is calculated to range between 0 and 3.85 MPa. Engineering cases indicate that blockages are challenging to remove after acidification, and the reduction in additional resistance is limited. This study provides a quantitative basis for understanding blockage patterns during water injection, helps predict changes in additional resistance, and offers a theoretical foundation for targeted treatment measures. Full article
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16 pages, 3946 KiB  
Article
Effect of Pyrolysis Temperature on the Carbon Sequestration Capacity of Spent Mushroom Substrate Biochar in the Presence of Mineral Iron
by Bin Liu, Zebing Xing, Yuxin Xue, Ji Zhang and Junlin Zhai
Molecules 2024, 29(23), 5712; https://doi.org/10.3390/molecules29235712 - 3 Dec 2024
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Abstract
The preparation of biochar typically involves the pyrolysis of waste organic biomass. Iron-rich magnetic biochar not only inherits the characteristics of high specific surface area and porous structure from biochar but also possesses significant advantages in easy separation and recovery, which has shown [...] Read more.
The preparation of biochar typically involves the pyrolysis of waste organic biomass. Iron-rich magnetic biochar not only inherits the characteristics of high specific surface area and porous structure from biochar but also possesses significant advantages in easy separation and recovery, which has shown great application potential in various fields such as soil improvement and water resource remediation. This study aims to explore the influence of mineral iron on the carbon sequestration capability of biochar during the pyrolysis process. Experiments were conducted by using spent mushroom substrates as raw materials to prepare biochar at different temperature intervals (300 to 600 °C). The addition of exogenous iron has been found to significantly enhance the carbon retention rate (12.2–44.5%) of biochar across various pyrolysis temperatures and, notably, improves the carbon stability of biochar at 300 °C, 400 °C, and 600 °C. Through the analysis of thermogravimetric mass spectrometry (TG-MS) and X-ray photoelectron spectroscopy (XPS), we discovered that iron catalyzes the thermochemical reactions and inhibits the release of organic small molecules (C2-C5) through both physical blocking (FexOx) and chemical bonding (C=O and O-C=O). The results of Raman spectroscopy and infrared spectroscopy analyses indicate that the addition of iron significantly promotes the graphitization process of carbon and enhances the thermal stability of biochar within the temperature range of 300 to 500 °C. When exploring the retention and stability of carbon during pyrolysis, it was found that under the conditions of 600 °C and the presence of iron, the maximum carbon sequestration rate of biochar can reach 60.6%. Overall, this study highlights the critical role of iron and pyrolysis temperature in enhancing the carbon sequestration capacity of biochar. Full article
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