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9,126 Results Found

  • Article
  • Open Access
8 Citations
4,482 Views
17 Pages

Speeding up Statistical Tolerance Analysis to Real Time

  • Peter Grohmann and
  • Michael S. J. Walter

5 May 2021

Statistical tolerance analysis based on Monte Carlo simulation can be applied to obtain a cost-optimized tolerance specification that satisfies both the cost and quality requirements associated with manufacturing. However, this process requires time-...

  • Article
  • Open Access
5 Citations
3,090 Views
21 Pages

20 April 2020

Tolerance analysis is becoming increasingly important for tolerance design and optimization. When dealing with electromechanical products such as the array antenna, the form errors of the assembly must be considered. Traditional tolerance analysis wi...

  • Feature Paper
  • Article
  • Open Access
15 Citations
5,256 Views
15 Pages

Statistical Tolerance Analysis—A Survey on Awareness, Use and Need in German Industry

  • Michael S. J. Walter,
  • Christina Klein,
  • Björn Heling and
  • Sandro Wartzack

16 March 2021

The importance of geometric deviations of components for the aesthetic and functional quality of products has been undisputed for decades. So, it is not surprising that not only have numerous researchers devoted themselves to this field, but also com...

  • Article
  • Open Access
7 Citations
3,312 Views
19 Pages

Comparative Gene Enrichment Analysis for Drought Tolerance in Contrasting Maize Genotype

  • Syed Faheem Anjum Gillani,
  • Adnan Rasheed,
  • Asim Abbasi,
  • Yasir Majeed,
  • Musawer Abbas,
  • Muhammad Umair Hassan,
  • Sameer H. Qari,
  • Najat Binothman,
  • Najla Amin T. Al Kashgry and
  • Yunling Peng
  • + 1 author

22 December 2022

Drought stress is a significant abiotic factor influencing maize growth and development. Understanding the molecular mechanism of drought tolerance is critical to develop the drought tolerant genotype. The identification of the stress responsive gene...

  • Article
  • Open Access
3 Citations
2,132 Views
13 Pages

QTL Detection of Salt Tolerance at Soybean Seedling Stage Based on Genome-Wide Association Analysis and Linkage Analysis

  • Maolin Sun,
  • Tianxin Zhao,
  • Shuang Liu,
  • Jinfeng Han,
  • Yuhe Wang,
  • Xue Zhao,
  • Yongguang Li,
  • Weili Teng,
  • Yuhang Zhan and
  • Yingpeng Han

16 August 2024

The utilization of saline land is a global challenge, and cultivating salt-tolerant soybean varieties is beneficial for improving the efficiency of saline land utilization. Exploring the genetic basis of salt-tolerant soybean varieties and developing...

  • Article
  • Open Access
5 Citations
2,556 Views
29 Pages

SYSML4TA: A SysML Profile for Consistent Tolerance Analysis in a Manufacturing System Case Application

  • Sergio Benavent-Nácher,
  • Pedro Rosado Castellano,
  • Fernando Romero Subirón and
  • José Vicente Abellán-Nebot

16 March 2023

Tolerance analysis is a key engineering task that is usually supported by domain-specific analysis models and tools that are generally not connected to the system functionality. The model-based system engineering (MBSE) approach is a potential soluti...

  • Article
  • Open Access
13 Citations
3,331 Views
26 Pages

Assessing the Suitability of Selection Approaches and Genetic Diversity Analysis for Early Detection of Salt Tolerance of Barley Genotypes

  • Muhammad Matloob Javed,
  • Abdullah A. Al-Doss,
  • Muhammad Usman Tahir,
  • Muhammad Altaf Khan and
  • Salah El-Hendawy

19 December 2022

Assessment of the salt tolerance of a large genotype collection at the early growth stages may assist in the fast-tracking improvement of salt-tolerant barley genotypes in breeding programs. This study aimed to investigate the ability of traits relat...

  • Article
  • Open Access
1,213 Views
16 Pages

Identification of Key Waterlogging-Tolerance Genes in Cultivated and Wild Soybeans via Integrated QTL–Transcriptome Analysis

  • Yiran Sun,
  • Lin Chen,
  • Yuxin Jin,
  • Shukun Wang,
  • Shengnan Ma,
  • Lin Yu,
  • Chunshuang Tang,
  • Yuying Ye,
  • Mingxuan Li and
  • Mingliang Yang
  • + 6 authors

8 August 2025

Soybean (Glycine max), as an important crop for both oil and grains, is a major source of high-quality plant proteins for humans. Among various natural disasters affecting soybean production, waterlogging is one of the key factors leading to yield re...

  • Feature Paper
  • Article
  • Open Access
11 Citations
4,129 Views
15 Pages

19 November 2021

Tolerance analysis is crucial in every manufacturing process, such as electrical machine design, because tight tolerances lead to high manufacturing costs. A FEM-based solution of the tolerance analysis of an electrical machine can easily lead to a c...

  • Article
  • Open Access
23 Citations
5,492 Views
21 Pages

Flooding negatively affects the growth of soybeans. Recently, omic approaches have been used to study abiotic stress responses in plants. To explore flood-tolerant genes in soybeans, an integrated approach of proteomics and computational genetic modi...

  • Article
  • Open Access
19 Citations
3,974 Views
18 Pages

20 February 2021

Fused Deposition Modelling (FDM) enables the fabrication of entire non-assembly mechanisms within a single process step, making previously required assembly steps dispensable. Besides the advantages of FDM, the manufacturing of these mechanisms impli...

  • Essay
  • Open Access
5 Citations
2,504 Views
23 Pages

14 December 2022

A method based on an interval arithmetic is proposed to analyze uncertain factors such as the curvature radii, excitation amplitude, and excitation phase of a spherical conformal array antenna. An interval description of element factors under differe...

  • Article
  • Open Access
25 Citations
3,311 Views
15 Pages

Comparison of Maize Genotypes Using Drought-Tolerance Indices and Graphical Analysis under Normal and Humidity Stress Conditions

  • Seyed Habib Shojaei,
  • Khodadad Mostafavi,
  • Ali Omrani,
  • Árpád Illés,
  • Csaba Bojtor,
  • Saeed Omrani,
  • Seyed Mohammad Nasir Mousavi and
  • János Nagy

30 March 2022

This study aimed to identify drought-tolerant genotypes and to evaluate and compare the response of genotypes under normal conditions and humidity stress. The experiment was conducted in a Randomized Complete Block Design (RCBD) on 12 commercial sing...

  • Article
  • Open Access
42 Citations
4,628 Views
22 Pages

Detailed Genetic Analysis for Identifying QTLs Associated with Drought Tolerance at Seed Germination and Seedling Stages in Barley

  • Yasser S. Moursi,
  • Samar G. Thabet,
  • Ahmed Amro,
  • Mona F. A. Dawood,
  • P. Stephen Baenziger and
  • Ahmed Sallam

24 October 2020

Drought induces several challenges for plant development, growth, and production. These challenges become more severe, in particular, in arid and semiarid countries like Egypt. In terms of production, barley ranks fourth after wheat, maize, and rice....

  • Article
  • Open Access
2 Citations
2,748 Views
25 Pages

The main problems of automotive wireless power transmission (WPT) systems include a weak misalignment tolerance are urgently required to be solved through the design of the loosely coupled transformer. In this paper, an analysis methodology based on...

  • Article
  • Open Access
39 Citations
7,177 Views
30 Pages

A Meta-Analysis of Comparative Transcriptomic Data Reveals a Set of Key Genes Involved in the Tolerance to Abiotic Stresses in Rice

  • Matteo Buti,
  • Elena Baldoni,
  • Elide Formentin,
  • Justyna Milc,
  • Giovanna Frugis,
  • Fiorella Lo Schiavo,
  • Annamaria Genga and
  • Enrico Francia

12 November 2019

Several environmental factors, such as drought, salinity, and extreme temperatures, negatively affect plant growth and development, which leads to yield losses. The tolerance or sensitivity to abiotic stressors are the expression of a complex machine...

  • Article
  • Open Access
4 Citations
6,903 Views
16 Pages

Pseudomonas aeruginosa causes chronic infections, such as cystic fibrosis, endocarditis, bacteremia, and sepsis, which are life-threatening and difficult to treat. The lack of antibiotic response in P. aeruginosa is due to adaptive resistance mechani...

  • Article
  • Open Access
14 Citations
3,362 Views
13 Pages

New Genes Identified as Modulating Salt Tolerance in Maize Seedlings Using the Combination of Transcriptome Analysis and BSA

  • Yongxing Zhu,
  • Ying Ren,
  • Ji’an Liu,
  • Wenguang Liang,
  • Yuanyuan Zhang,
  • Fengyuan Shen,
  • Jiang Ling and
  • Chunyi Zhang

15 March 2023

(1) Background: Salt stress is an abiotic factor that limits maize yield and quality. A highly salt-tolerance inbred AS5 and a salt-sensitive inbred NX420 collected from Ningxia Province, China, were used to identify new genes for modulating salt res...

  • Article
  • Open Access
30 Citations
5,916 Views
15 Pages

6 January 2023

Drought severely affects crop yield and yield stability. Maize and sorghum are major crops in Africa and globally, and both are negatively impacted by drought. However, sorghum has a better ability to withstand drought than maize. Consequently, this...

  • Review
  • Open Access
10 Citations
4,588 Views
33 Pages

6 December 2023

The size of wind turbine blades is increasing rapidly, and they are being installed in remote offshore locations. Consequently, it is essential to focus on improving the design and maintenance procedures in the blade industry to meet the growing dema...

  • Article
  • Open Access
5 Citations
1,823 Views
15 Pages

9 October 2021

In this paper a stability analysis of microperiodic beams resting on the periodic inhomogeneous foundation is carried out. The main issue of this considerations, which is the analytical solution to the governing equations characterised by periodic, h...

  • Article
  • Open Access
3 Citations
2,678 Views
21 Pages

Mining Salt Tolerance SNP Loci and Prediction of Candidate Genes in the Rice Bud Stage by Genome-Wide Association Analysis

  • Rui Wang,
  • Zhenzhen Zhou,
  • Mengyuan Xiong,
  • Mingyu Du,
  • Xingxing Lin,
  • Cuiping Liu,
  • Mingwei Lu,
  • Zhengbo Liu,
  • Yinping Chang and
  • Erbao Liu

30 May 2023

Mining salt tolerance genes is significant for breeding high-quality salt-tolerant rice varieties in order to improve the utilization of saline–alkaline land. In this study, 173 rice accessions were measured for their germination potential (GP)...

  • Article
  • Open Access
2,113 Views
17 Pages

Transcriptomic Analysis of Maize Inbred Lines with Different Leaf Shapes Reveals Candidate Genes and Pathways Involved in Density Tolerance

  • Shulei Guo,
  • Yiyang Guo,
  • Jun Zhang,
  • Yinghui Song,
  • Jinsheng Guo,
  • Liangming Wei,
  • Qianjin Zhang,
  • Zhenhua Wang,
  • Zanping Han and
  • Xiaomin Lu
  • + 2 authors

11 July 2024

Maize is an important food and feed crop. Under limited arable land area, the cultivation of high-density-tolerance crops is a key factor in promoting yield improvement. Leaf width and stalk strength are important influences on density tolerance in m...

  • Article
  • Open Access
513 Views
18 Pages

Tolerance Analysis of Test Mass Alignment Errors for Space-Based Gravitational Wave Detection

  • Jun Ke,
  • Ruihong Gao,
  • Jinghan Liu,
  • Mengyang Zhao,
  • Ziren Luo,
  • Jia Shen and
  • Peng Dong

4 December 2025

Space-based gravitational wave detection imposes extremely high requirements on displacement measurement accuracy, with its core measurement components being laser interferometers and inertial sensors. The laser interferometers detect gravitational w...

  • Article
  • Open Access
53 Citations
7,301 Views
18 Pages

Trehalose is a nonreducing α,α-1,1-disaccharide in a wide range of organisms, and has diverse biological functions that range from serving as an energy source to acting as a protective/signal sugar. However, significant amounts of trehalose have rare...

  • Review
  • Open Access
1 Citations
1,782 Views
25 Pages

Reference Tolerance Ellipses in Bioelectrical Impedance Vector Analysis Across General, Pediatric, Pathological, and Athletic Populations: A Scoping Review

  • Sofia Serafini,
  • Gabriele Mascherini,
  • Raquel Vaquero-Cristóbal,
  • Francisco Esparza-Ros,
  • Francesco Campa and
  • Pascal Izzicupo

Background: Bioelectrical Impedance Vector Analysis (BIVA) is a qualitative method that standardizes resistance and reactance relative to stature (R/H and Xc/H) and plots them as vectors on an R-Xc graph. This equation-free approach assesses body com...

  • Article
  • Open Access
2 Citations
2,144 Views
17 Pages

17 September 2024

Cultivated soybean is an important legume crop that is generally sensitive to flooding stress, including submergence and waterlogging treatments. Wild soybeans, the ancestor of cultivated soybeans, have been potential genetic resources for resistance...

  • Article
  • Open Access
12 Citations
5,946 Views
21 Pages

Two-State Co-Expression Network Analysis to Identify Genes Related to Salt Tolerance in Thai Rice

  • Apichat Suratanee,
  • Chidchanok Chokrathok,
  • Panita Chutimanukul,
  • Nopphawitchayaphong Khrueasan,
  • Teerapong Buaboocha,
  • Supachitra Chadchawan and
  • Kitiporn Plaimas

29 November 2018

Khao Dawk Mali 105 (KDML105) rice is one of the most important crops of Thailand. It is a challenging task to identify the genes responding to salinity in KDML105 rice. The analysis of the gene co-expression network has been widely performed to prior...

  • Article
  • Open Access
2 Citations
856 Views
16 Pages

Isolation and Expression Pattern Analysis of Larix olgensis LoNAC5: LoNAC5 Acts as a Positive Regulator of Drought and Salt Tolerance

  • Qing Cao,
  • Junjie Du,
  • Mengxu Yin,
  • Chen Wang,
  • Tiantian Zhang,
  • Qingrong Zhao,
  • Lu Liu,
  • Hanguo Zhang and
  • Lei Zhang

19 May 2025

NAC transcription factors are a kind of plant specific transcription factor widely distributed in plants, and they play an important role in the process of plant growth and development. According to the transcriptome data, a transcription factor with...

  • Article
  • Open Access
1 Citations
2,062 Views
15 Pages

29 November 2023

As a temperature-loving crop, rice is sensitive to low temperatures. With the popularization of direct-seeded rice, cold tolerance (CT) at the bud burst stage has become an important breeding goal. Here, we evaluated CT for 513 rice accessions at the...

  • Article
  • Open Access
30 Citations
4,725 Views
18 Pages

The aquaporins (AQPs) are a family of integral membrane proteins involved in the transcellular membrane transport of water and other small molecules. A scan of the apple (Malus domestica) genome revealed the presence of 42 genes encoding putative AQP...

  • Article
  • Open Access
1 Citations
1,349 Views
20 Pages

1 April 2025

Vibrio parahaemolyticus, a halophilic Gram-negative bacterium commonly found in aquatic products, can colonize the human small intestine, causing gastroenteritis and potentially leukemia. As a major intestinal pathogen, it poses a significant threat...

  • Review
  • Open Access
25 Citations
5,213 Views
18 Pages

Gene Mapping, Cloning and Association Analysis for Salt Tolerance in Rice

  • Xiaoru Fan,
  • Hongzhen Jiang,
  • Lijun Meng and
  • Jingguang Chen

28 October 2021

Soil salinization caused by the accumulation of sodium can decrease rice yield and quality. Identification of rice salt tolerance genes and their molecular mechanisms could help breeders genetically improve salt tolerance. We studied QTL mapping of p...

  • Article
  • Open Access
12 Citations
2,589 Views
18 Pages

24 February 2024

Caffeic acid O-methyltransferase (COMT) participates in various physiological activities in plants, such as positive responses to abiotic stresses and the signal transduction of phytohormones. In this study, 18 COMT genes were identified in the chrom...

  • Article
  • Open Access
3 Citations
1,152 Views
15 Pages

Comparative Transcriptome and Hormonal Analysis Reveals the Mechanisms of Salt Tolerance in Rice

  • Dingsha Jin,
  • Yanchao Xu,
  • Asif Iqbal,
  • Yuqing Liu,
  • Yage Zhang,
  • Youzhen Lin,
  • Liqiong Tang,
  • Xinhua Wang,
  • Junjie Wang and
  • Xiaoning Wang
  • + 2 authors

Salt stress is a major constraint to seed germination and early seedling growth in rice, affecting crop establishment and productivity. To understand the mechanisms underlying salt tolerance, we investigated two rice varieties with contrasting respon...

  • Article
  • Open Access
42 Citations
5,258 Views
22 Pages

Association Analysis of Drought Tolerance and Associated Traits in Upland Cotton at the Seedling Stage

  • Hai-Ming Li,
  • Shao-Dong Liu,
  • Chang-Wei Ge,
  • Xiao-Meng Zhang,
  • Si-Ping Zhang,
  • Jing Chen,
  • Qian Shen,
  • Fei-Yan Ju,
  • Yong-Fei Yang and
  • Chao-You Pang
  • + 5 authors

(1) Background: Upland cotton (Gossypium hirsutum L.) is the most important natural fiber worldwide, and it is extensively planted and plentifully used in the textile industry. Major cotton planting regions are frequently affected by abiotic stress,...

  • Communication
  • Open Access
885 Views
9 Pages

28 August 2025

A deployable reflectarray antenna (RA) using a three-times expansion structure working at the V-band for 12U CubeSat is presented in this paper. Double-circle ring unit cells with excellent dispersion characteristics are used to constitute the layout...

  • Article
  • Open Access
3 Citations
3,116 Views
28 Pages

Monte-Carlo Analysis of the Influence of the Electrical Component Tolerances on the Behavior of Series-Series- and LCC-Compensated IPT Systems

  • Francisco Javier López-Alcolea,
  • Javier Vázquez,
  • Emilio J. Molina-Martínez,
  • Pedro Roncero-Sánchez and
  • Alfonso Parreño Torres

16 July 2020

The use of compensation networks increases the power transfer capability of inductive power transfer (IPT) systems in the battery charging process of electric vehicles (EVs). Among the proposed topologies, the Series-Series (SS) and the LCC networks...

  • Article
  • Open Access
2 Citations
3,155 Views
25 Pages

28 February 2024

Salt stress is a significant challenge that severely hampers rice growth, resulting in decreased yield and productivity. Over the years, researchers have identified biomarkers associated with salt stress to enhance rice tolerance. However, the unders...

  • Article
  • Open Access
8 Citations
3,558 Views
19 Pages

Design and Analysis of a Stiffness-Enhanced 3-PPS Parallel Mechanism for Fault-Tolerant Underwater Vectored Thrusters

  • Dexin Jiang,
  • Tianjiang Zheng,
  • Guilin Yang,
  • Yingzhong Tian,
  • Zaojun Fang,
  • Huamin Li,
  • Chi Zhang and
  • Hongwu Ye

25 January 2022

Vectored thrusters can significantly improve the maneuverability of underwater vehicles. However, due to the harsh underwater environment and severe working conditions, the thrust-vectoring device needs to be designed with high stiffness and high rel...

  • Article
  • Open Access
7 Citations
2,642 Views
23 Pages

20 September 2023

Salinity is amongst the serious abiotic stresses cotton plants face, impairing crop productivity. Foliar application of β-alanine is employed to improve salt tolerance in various crops, but the exact mechanism behind it is not yet completely und...

  • Article
  • Open Access
20 Citations
4,575 Views
17 Pages

γ-Polyglutamic Acid Production, Biocontrol, and Stress Tolerance: Multifunction of Bacillus subtilis A-5 and the Complete Genome Analysis

  • Naling Bai,
  • Yu He,
  • Hanlin Zhang,
  • Xianqing Zheng,
  • Rong Zeng,
  • Yi Li,
  • Shuangxi Li and
  • Weiguang Lv

Bacillus subtilis A-5 has the capabilities of high-molecular-weight γ-PGA production, antagonism to plant pathogenic fungi, and salt/alkaline tolerance. This multifunctional bacterium has great potential for enhancing soil fertility and plant s...

  • Article
  • Open Access
1 Citations
1,076 Views
17 Pages

Transcriptome Analysis Reveals Differences in Molecular Mechanisms Between Salt-Tolerant and Salt-Sensitive Rice (Oryza sativa L.) Varieties Under Salt Stress

  • Yu Han,
  • Chenyang Wu,
  • Xue Ji,
  • Mengran Yang,
  • Hongyu Zhu,
  • Zhongyou Pei,
  • Mingnan Qu,
  • Lijun Qu,
  • Zhibin Li and
  • Shuangyong Yan

To elucidate the molecular mechanisms underlying salt tolerance in rice (Oryza sativa L.), this study investigated differential transcriptional responses during the tillering stage. Salt-tolerant (N14) and salt-sensitive (N6) varieties were subjected...

  • Article
  • Open Access
4 Citations
2,408 Views
15 Pages

Multilevel inverters are increasingly used in industrial applications in which service continuity is crucial. This paper presents an original approach to ensure the fault-tolerant operation of neutral-point-clamped (NPC) inverters in the case of an o...

  • Article
  • Open Access
30 Citations
3,927 Views
16 Pages

Comparative Transcriptome Analysis of Two Sweet Sorghum Genotypes with Different Salt Tolerance Abilities to Reveal the Mechanism of Salt Tolerance

  • Chengxuan Chen,
  • Xiaoling Shang,
  • Meiyu Sun,
  • Sanyuan Tang,
  • Aimal Khan,
  • Dan Zhang,
  • Hongdong Yan,
  • Yanxi Jiang,
  • Feifei Yu and
  • Qi Xie
  • + 1 author

18 February 2022

Sweet sorghum is a C4 crop that can be grown for silage forage, fiber, syrup and fuel production. It is generally considered a salt-tolerant plant. However, the salt tolerance ability varies among genotypes, and the mechanism is not well known. To fu...

  • Article
  • Open Access
19 Citations
7,516 Views
25 Pages

Integrative Analysis of the Ethanol Tolerance of Saccharomyces cerevisiae

  • Ivan Rodrigo Wolf,
  • Lucas Farinazzo Marques,
  • Lauana Fogaça de Almeida,
  • Lucas Cardoso Lázari,
  • Leonardo Nazário de Moraes,
  • Luiz Henrique Cardoso,
  • Camila Cristina de Oliveira Alves,
  • Rafael Takahiro Nakajima,
  • Amanda Piveta Schnepper and
  • Guilherme Targino Valente
  • + 17 authors

Ethanol (EtOH) alters many cellular processes in yeast. An integrated view of different EtOH-tolerant phenotypes and their long noncoding RNAs (lncRNAs) is not yet available. Here, large-scale data integration showed the core EtOH-responsive pathways...

  • Article
  • Open Access
5 Citations
3,910 Views
16 Pages

Single-layer reticulated shell structures are widely used, but their stability performance is not ideal. Moreover, they are sensitive to structural damage and imperfections, while the existing conventional design methods of increasing the cross-secti...

  • Article
  • Open Access
373 Views
22 Pages

Exploring the Genetic Foundations of Salt Tolerance in Common Vetch (Vicia sativa L.) via Genome-Wide Association Analysis

  • Hui Jin,
  • Jumei Zhang,
  • Yordan Dimtrov,
  • Xue Yang,
  • Ruonan Du,
  • Yu-e Wu,
  • Danna Chang,
  • Rui Zhang and
  • Haibin Zhao

30 December 2025

Background/Objectives: Common vetch (Vicia sativa L.) is a globally cultivated leguminous crop, valued for its high nutritional content and role in sustainable agriculture. Methods: To identify loci or genes significantly associated with salt toleran...

  • Article
  • Open Access
302 Views
12 Pages

Fine-Mapping and Candidate Gene Analysis of qAT3 for Alkalinity Tolerance in Rice

  • Lei Lei,
  • Jinsong Zhou,
  • Guohua Ding,
  • Liangzi Cao,
  • Yu Luo,
  • Lei Chen,
  • Yang Ren,
  • Jiangxu Wang,
  • Kai Liu and
  • Shichen Sun
  • + 4 authors

6 February 2026

Salinity–alkalinity stress is one of the major abiotic stresses that limit rice production in the world. The salinity–alkalinity tolerance of rice at the germination stage has a direct effect on the survival and final yield of seedlings i...

  • Review
  • Open Access
14 Citations
6,530 Views
33 Pages

Phenylalanine Tolerance over Time in Phenylketonuria: A Systematic Review and Meta-Analysis

  • Alex Pinto,
  • Fatma Ilgaz,
  • Sharon Evans,
  • Esther van Dam,
  • Júlio César Rocha,
  • Erdem Karabulut,
  • Mary Hickson,
  • Anne Daly and
  • Anita MacDonald

8 August 2023

In phenylketonuria (PKU), natural protein tolerance is defined as the maximum natural protein intake maintaining a blood phenylalanine (Phe) concentration within a target therapeutic range. Tolerance is affected by several factors, and it may differ...

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