Search Results (3,324)

Nuclear energy is a clean and efficient energy source crucial for the future energy supply. The harsh conditions in reactors, including high temperature, high pressure, and intense neutron irradiation, cause structural materials to accumulate irradiation damage, leading to performance degradation. Austenitic stainless steel, due to its superior mechanical properties, irradiation resistance, and corrosion resistance, has been extensively utilized as a core structural material in light water reactors and emerged as a candidate material for Generation IV nuclear reactors. Therefore, understanding irradiation damage and macroscopic properties evolution in austenitic stainless steels is critical for enhancing the safety and long-term service life of reactor core materials. This review began by elucidating the application of charged particles in irradiation studies, emphasizing the prevailing substitution of neutron irradiation with proton irradiation experiments in current studies. Subsequently, the work systematically synthesized irradiation damages and their consequential impacts on macroscopic properties. Finally, it consolidated the progress and provided prospects for research on improving the resistance of austenitic stainless steel to irradiation-induced segregation, irradiation hardening, irradiation swelling, and irradiation-corrosion synergies. Full article

Oxalis tuberosa (Oca) is traditionally cultivated in the high Andean regions of Peru and represents a promising alternative source of starch with potential industrial uses, ranking among the most essential tubers after the potato. This study aimed to evaluate the physicochemical, morphological, techno-functional, and thermal properties of starch isolated from three specific varieties of Oca (yellow, black, and white) harvested at the Ccanccayllo production center in Andahuaylas, Peru. The isolated starches exhibited high purity, characterized by high luminosity (L* > 92.28) and a whiteness index exceeding 92.10. Moisture content ranged from 9.36% to 10.01%, correlating with low water activity (a_w = 0.44), indicating stability. Notably, the amylose content was significantly higher than that of other previously studied Oca varieties. This composition contributed to a favorable water absorption capacity, solubility index, swelling power, and viscosity, with the white variety displaying superior functional performance. Colloidal stability in aqueous media was moderate, as indicated by zeta potential analysis. Particle size analysis revealed granules ranging from 26.32 to 27.74 μm, with elongated and oval morphologies confirmed by SEM, displaying characteristic functional groups. Thermal analysis (DSC) demonstrated gelatinization temperatures between 52.73 and 53.12 °C and enthalpies ranging from 4.92 to 6.11 J/g, while Thermogravimetric Analysis (TGA) indicated thermal degradation up to approximately 74–80%. These findings suggest that the studied Oca starches possess significant potential for application in the food and pharmaceutical industries due to their distinct functional properties. Full article

This study systematically evaluated the potential of five native starches, including corn (CS), potato (PS), tapioca (TS), rice (RS), and sweet potato (SPS), as fat replacers in low-fat pork sausages. The obtained results showed that amylose content varied significantly, with PS and SPS having the highest levels (30.06% and 28.60%, respectively), which were beneficial for forming starch gels. Correspondingly, PS and SPS demonstrated the highest solubility and swelling power. In sausage applications, PS and SPS exhibited superior water-retention capacities, with drying losses of 6.75% and 7.03%, and cooking losses of 2.23% and 2.52%, which were lower than those of the normal control (NC) and low-fat control (LFC) groups. Moreover, the results of texture profile analysis revealed that PS and SPS enabled the sausages to achieve the highest levels of hardness and springiness, contributing to maintaining the moisture retention and toughness of the sausages. Electronic tongue and nose analyses indicated that incorporating these starches did not adversely affect the taste and odor profiles of the sausages, except for RS, which showed distinct flavor encapsulation properties. Overall, PS and SPS served as excellent fat replacers in the meat industry, offering healthier alternatives without compromising product quality. Full article

Poly(vinyl alcohol)/chitosan (PVA/CS) biodegradable films reinforced with acid-functionalized multi-walled carbon nanotubes (f-MWCNTs) were fabricated via solution casting to investigate the effects of nanotube incorporation on structural, mechanical, thermal, dielectric, and physicochemical properties. Unlike conventional CNT-reinforced systems, this study focuses on the role of acid functionalization in improving nanotube dispersion and interfacial interactions, enabling simultaneous enhancement of multiple performance characteristics. Fourier transform infrared spectroscopy (FTIR) analysis confirmed strong intermolecular interactions between PVA/CS functional groups and carboxyl groups on f-MWCNTs, while scanning electron microscopy (SEM) revealed homogeneous nanotube dispersion at low loadings and partial aggregation at higher contents. X-ray diffraction (XRD) indicated that crystallinity was modified in a non-monotonic manner with increasing nanotube concentration due to competing nucleation and chain-restriction effects, while dielectric measurements showed an increase in dielectric constant from 3.78 to 4.27 as a result of enhanced interfacial polarization. The thermal conductivity improved from 0.195 to 0.247 W·m⁻¹·K⁻¹, and tensile strength increased from 19.8 to 24.5 MPa at 0.2 wt.% f-MWCNT, with elongation at break decreasing from 37.9% to 25.1%, reflecting increased stiffness. The degree of swelling and water solubility decreased with higher nanotube content, indicating reduced hydrophilicity and enhanced structural compactness. The results provide new insights into how surface-functionalized nanofillers can be used to tailor the multifunctional performance of biodegradable polymer nanocomposite films, highlighting their potential in advanced applications such as sustainable packaging, flexible electronics, sensors, and membrane technologies. Full article

To address inherent limitations of chitosan-based edible films, including inadequate mechanical strength and poor moisture resistance, cellulose nanofibers (CNF) were employed as a synergistic film-forming component to partially substitute chitosan in the fabrication of ternary composite films (denoted as CSTF-CNFs). This approach was based on a previously developed chitosan matrix modified with tannin-Fe³⁺ nanoparticles (TF). It was hypothesized that CNF could function as a reinforcing scaffold to improve the dispersion of TF within the film matrix and, through hydrogen bonding and physical entanglement, form an interpenetrating fiber network with chitosan, thereby enhancing the structural and barrier properties of the films. The present study systematically evaluated the influence of varying CNF substitution ratios (0–30%) on the physicochemical characteristics of the resulting composite films and their performance in tomato preservation. The results demonstrated that an appropriate CNF incorporation facilitated the formation of a dense, cross-linked network with chitosan and TF via hydrogen bond interactions, significantly improving both mechanical strength and water resistance. Among all formulations, the CSTF-CNF20 film exhibited optimal comprehensive performance, achieving the highest tensile strength of 27.60 MPa. Moreover, its swelling ratio markedly decreased from 675.5% (CSTF-CNF0) to 120.9%, while the water contact angle increased to 113.7°, and the DPPH radical scavenging activity remained above 85%. Tomato preservation assays revealed that, in comparison with the untreated control and polyethylene film-wrapped groups, the application of CSTF-CNF20 coating effectively mitigated the decline in weight loss and firmness, preserved surface color integrity, and resulted in the highest L* value alongside the lowest soluble solids content. These findings suggest that the synergistic integration of CNF with nano-scale metal–phenolic networks offers a viable strategy for developing high-performance chitosan-based edible films. The CSTF-CNF20 composite film holds significant promise for application in the postharvest preservation of fruits and vegetables. Full article

The synergistic utilization of waste plastics and tires in asphalt modification is a highly promising sustainable strategy. However, the differential impacts of distinct plastic molecular architectures on the performance and network evolution of rubber-modified asphalt remain fundamentally unclear. This study systematically investigated the physical, rheological, and microstructural properties of composite asphalts modified with desulfurized rubber powder (DRP) and four representative plastics: polyethylene (PE), styrene–isoprene–styrene (SIS), styrene–ethylene–butylene–styrene (SEBS), and styrene–butadiene–styrene (SBS). Furthermore, the pavement performance of the asphalt mixtures prepared via dry and wet methods was comparatively evaluated. Microstructural and spectroscopic analyses revealed that the composite modification was primarily governed by physical blending and swelling. The non-polar, semi-crystalline PE resulted in severe phase separation and extreme low-temperature brittleness. Conversely, the saturated hydrogenated mid-blocks of SEBS endowed the asphalt with the highest high-temperature rutting resistance but severely compromised its low-temperature stress relaxation. Remarkably, SBS interacted synergistically with DRP to form a highly homogeneous and densely interwoven three-dimensional network, thereby achieving an optimal viscoelastic balance, outstanding storage stability, and superior low-temperature ductility. Pavement performance tests further demonstrated that the wet method significantly outperformed the dry method for block copolymers by facilitating sufficient pre-swelling. Overall, the SBS-DRP composite-modified asphalt prepared via the wet method exhibited the most exceptional and balanced comprehensive pavement performance, providing a robust theoretical foundation for the sustainable and high-value recycling of multi-source solid wastes in paving engineering. Full article

The development of accident-tolerant fuels has significantly enhanced the safety of fission reactors. The TiNbZrO alloy system has garnered considerable attention due to its excellent mechanical properties and outstanding irradiation resistance. Its unique compositional design enables effective suppression of irradiation-induced defect formation. In this study, TiNbZrO thin films are fabricated via radio-frequency magnetron sputtering and irradiated with 50 keV He ions to fluences of 5 × 10¹⁶, 1 × 10¹⁷, and 2 × 10¹⁷ ions/cm². The microstructural evolution before and after irradiation is characterized by Transmission Electron Microscopy (TEM) and Grazing Incidence X-ray Diffraction (GIXRD), and the changes in mechanical properties are evaluated by nanoindentation. With increasing irradiation fluence, the average size of He bubbles increases from 1.10 nm to 2.06 nm, the number density decreases from 5.27 × 10²⁴ m⁻³ to 1.39 × 10²⁴ m⁻³, and the swelling rate rises from 0.37% to 0.64%. Although significant irradiation hardening is observed in all samples, the maximum hardening rate reaches only 31.91%, a value substantially lower than that reported for many conventional nuclear materials. This demonstrates the superior irradiation resistance of TiNbZrO thin films. The superior irradiation resistance of TiNbZrO thin films stems from two synergistic effects: high-entropy lattice distortion suppresses atomic diffusion, while oxygen complexes pin defects. Full article

Soil stabilizers using conventional cement and lime binders incur high environmental costs owing to CO₂ emissions associated with their excavation, production, and processing. This has motivated research on low-carbon, waste-derived alternatives. The review shows that: biochar increases unconfined compressive strength (UCS) by 15–40% with a 2–5% dosage through pore filling and particle binding; nanocellulose promotes soil cohesion by 25–60% through fibrous network development and tensile bridging; recycled PET powder at 5–10% increases shear strength by 20–35% promoting mechanical interlocking, increasing stiffness, crack resistance and durability. Biochar provides direct carbon sequestration with a carbon transfer capacity of up to 2.5 tons CO₂-eq/ton. Recycled PET introduces waste valorization, with the potential to divert millions of tons of annual PET waste, while nanocellulose provides indirect carbon savings by avoiding emissions from cement and lime replacement. This review’s objectives are as follows: providing a comprehensive comparison of biochar, nanocellulose, and PET powder as promising non-cement composite stabilizers; identifying optimal dosage ranges and stabilization mechanisms for each material across different soil types; and outlining knowledge gaps and future research directions in sustainable geotechnical practices. The review assessed the individual and synergistic effects of the additives on critical geotechnical properties, including unconfined compressive strength (UCS), California bearing ratio (CBR), resilient resistance, swelling resistance, and the durability of the treated soil. Findings provide actionable guidance for practitioners seeking to reduce construction carbon footprints while maintaining geotechnical performance standards. Research gaps were identified, and future directions for integrating high-performance, low-carbon soil composites into sustainable construction solutions are proposed. Full article

Optimizing nitrogen (N) fertilizer application within conventional rice production systems remains essential for improving grain quality while avoiding inefficient resource use. This study examined how different N application levels influence rice quality, starch structure, and physicochemical properties in two japonica rice types cultivated under cold-region conditions in Northeast China. Using two cultivars, common japonica rice ‘Putian 1498’ and glutinous japonica rice ‘Longjing 57’, four nitrogen levels were established under machine-transplanting conditions: N0 (0 kg/hm²), N1 (80 kg/hm²), N2 (135 kg/hm²), and N3 (190 kg/hm²). The results indicate that increasing nitrogen application differentially affected the milling quality of the two rice types: it reached its maximum at the N1 level for common japonica rice and at the N3 level for glutinous japonica rice. However, the taste value decreased and chalkiness increased in both types. Regarding starch properties, increased nitrogen application led to rougher starch granule surfaces, a decrease in large granules, and an increase in medium and small granules. Starch content decreased, and the amylose-to-amylopectin ratio declined. Relative crystallinity increased, while the FTIR ratio of 1045/1022 cm⁻¹ decreased. Solubility showed an increasing trend, whereas swelling power exhibited the opposite trend. The gelatinization enthalpy and pasting temperatures were positively correlated with nitrogen rate, whereas retrogradation degree showed a negative correlation. These results demonstrate that nitrogen application regulates rice quality through changes in starch structure and physicochemical properties, with distinct responses between common and glutinous japonica rice. Moderate nitrogen input improves milling quality, but excessive application reduces eating quality, indicating a trade-off between processing performance and consumer-oriented quality. This study provides mechanistic evidence to support more precise nitrogen management in conventional rice systems, contributing to improved resource-use efficiency without overstating broader sustainability claims. In conclusion, moderate nitrogen application optimizes rice quality by balancing milling performance and eating quality through its effects on starch structure, whereas excessive nitrogen input leads to quality deterioration and inefficient resource use. Full article

Yam starch accounts for 70–80% of its dry matter, and its physicochemical and technofunctional properties are crucial for its use in the food industry (gelling agent, thickener, and stabilizer). The objective of this study focuses on the physicochemical, pasting and thermal properties of starch extracted from the yam varieties Dioscorea cayenensis, Dioscorea alata, and Dioscorea rotundata. The proximal composition, amylose and amylopectin content, as well as their functional properties (absorption index, solubility, swelling, thermal and pasting behavior, morphology, and color) were analyzed. The results showed that the starch extraction yield varied between varieties, being highest in D. cayenensis with 14.14%. D. alata had the highest starch (82.24%) and amylose (34.69%) content, which gives it greater gel firmness and retrogradation potential, as well as the best techno-functional properties water absorption index (2.46 g/g), water solubility index (1.1%), and swelling power (2.54 g/g). D. cayenensis stands out for its high amylopectin content (69.62%) and brightness (96.89), reflecting greater starch whiteness. D. rotundata has an intermediate balance between amylose and amylopectin, which makes it versatile. The proximal composition and techno-functional properties of yam starch position it as a promising raw material for the food industry, especially in the manufacture of thickeners, gelling agents, and in bakery products, pasta and noodles. Full article

The physicochemical properties of starch in high-quality hybrid indica rice (HQR) varieties that have received the National High-Quality Rice Gold Award are not well characterized. Ten HQR and two ordinary-quality indica rice (OQR) varieties were selected for this study. All varieties were identically cultivated under late-season conditions in southern China and were subsequently analyzed for differences in taste-related attributes, amylopectin fine structure, and functional properties. Compared with OQR varieties, HQR varieties exhibited a distinct starch profile: lower amylose (16.6–20.2%) but higher amylopectin content (62.6–65.0%), a greater proportion of small and medium starch granules, and a higher ratio of A and B1 chains in amylopectin (with few exceptions). Functionally, HQR varieties showed significantly (p < 0.05) higher gel consistency, solubility, and swelling power, along with higher breakdown but lower setback. They also generally exhibited higher crystallinity and gelatinization enthalpy, alongside a softer texture. Notably, the functional properties showed strong correlations (p < 0.05) with most taste-related attributes and amylopectin fine structures across all varieties. These findings provide critical guidance for future breeding programs aimed at improving the quality of indica rice and developing new elite HQR varieties. Full article

Background/Objectives: Enteric drug forms are developed to delay drug release to avoid drug degradation in the acidic environment of the stomach or to prevent irritation of the stomach mucosa. The bioavailability of posaconazole (POS) after oral administration depends on stomach pH and food intake. Delayed-release tablets and unmodified oral suspension are the POS formulations currently available on the market. The oral suspension formulation is characterized by highly variable bioavailability, which may significantly affect therapy effectiveness. Methods: In this study, multi-unit drug forms with delayed and sustained POS release were designed. Polymeric microparticles consisting of sodium alginate (ALG), methacrylic acid–ethyl acrylate copolymer (EUD), or both, were prepared using the spray-drying technique. The formulations that met the pharmacopoeia enteric release standards in the in vitro dissolution test were subjected to further in vitro evaluation via swelling and mucoadhesion assays, an antifungal activity test, attenuated total reflectance–Fourier transform infrared spectroscopy (ATR-FTIR), and thermal analysis. Results: It was shown that EUD formulations at concentrations of 5% and 6% provided enteric release, whereas ALG at 1.5% concentration exhibited a sustained, although not delayed, POS release profile. The optimal blended formulations (EAP15–EAP18), comprising 4% EUD with 1.5–2.0% ALG and either 1% or 4% POS, met the pharmacopoeia criteria for enteric dosage forms. Furthermore, these blends demonstrated the most favorable sustained-release profiles in the buffer phase, ranging from 2 to 3 h. The microparticles exhibited beneficial swelling and mucoadhesive properties, which are essential for prolonging contact with the intestinal mucosa; combined with antifungal properties. Conclusions: Obtained carrier may provide a promising preliminary basis for developing a multi-unit, sustained-release enteric dosage form for POS and future in vivo investigations. Full article

To systematically investigate the combined effects of moisture content, confining pressure, and loading rate on the mechanical properties of weakly cemented soft rock, this study focuses on the Jurassic coal measures from the Hoxtolgay coalfield in Xinjiang. A series of uniaxial and triaxial compression tests were conducted under varying moisture states, loading velocities, and confining pressures. Complementary X-ray diffraction (XRD), scanning electron microscopy (SEM), and Brazilian splitting tests were performed to analyze the microstructural evolution and tensile failure characteristics. The experimental results demonstrate that moisture content acts as the primary governing factor for mechanical degradation; increased hydration promotes clay mineral swelling and attenuates inter-granular cementation, leading to a continuous reduction in both compressive and tensile strengths, as well as the elastic modulus. Conversely, confining pressure consistently enhances these macroscopic mechanical parameters by restricting lateral deformation. While the loading rate alters the mechanical response, its impact is secondary compared to the definitive effects of moisture and stress constraints. Furthermore, by utilizing established stress–strain-based indices, the study quantitatively evaluates the brittleness characteristics, confirming that hydration fundamentally drives the rock mass from a brittle state toward ductility. This research elucidates the coupled degradation mechanisms of highly sensitive soft rock, providing a theoretical foundation for stability design and risk assessment in underground geotechnical engineering. Full article

Conventional therapies for rheumatoid arthritis (RA) are limited by poor selectivity, insufficient modulation of the oxidative inflammatory microenvironment, and systemic side effects. Oxidative stress and macrophage-driven immune dysregulation represent critical therapeutic targets. Cinnamaldehyde (CA) and arginine (Arg) possess antioxidant, anti-inflammatory, and anti-osteoclastogenic activities, but their poor solubility, instability, and lack of targeting restrict clinical application. Here, we report a pH-responsive cinnamaldehyde–arginine nanoprodrug (Arg-CA NPs), synthesized via Schiff base reaction, that spontaneously self-assembles into uniform nanoparticles capable of acid-triggered dual-drug release. Arg-CA NPs enhanced the solubility and stability of CA, exhibited excellent dispersibility and circulatory stability, and demonstrated intrinsic antioxidant and anti-inflammatory properties. Mechanistically, Arg-CA NPs attenuated intracellular ROS accumulation, preserved mitochondrial function, and reprogrammed macrophages toward an anti-inflammatory M2 phenotype by suppressing hypoxia-inducible factor-1α (HIF-1α), cyclooxygenase-2 (COX-2), and nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) signaling. In an adjuvant-induced arthritis (AIA) rat model, Arg-CA NPs selectively accumulated in inflamed joints and significantly alleviated joint swelling, synovial inflammation, cartilage erosion, and bone destruction. These findings identify Arg-CA NPs as a promising redox-active nanoplatform for RA therapy by targeting oxidative stress and immune dysregulation. Full article

Chitin-based hydrogels have emerged as a versatile and sustainable material with significant potential in biomedical, environmental, and energy applications. Derived from the abundant biopolymer chitin, these hydrogels exhibit exceptional biocompatibility, biodegradability, and tunable physicochemical properties. This review highlights advances in chitin-based hydrogels, focusing on solvent systems, crosslinking strategies, and structural modifications to enhance mechanical strength, swelling, and stimuli responsiveness. Key applications include wound healing, drug delivery, tissue engineering, and environmental remediation, where their high-water retention, enzymatic degradability, and eco-friendly nature are particularly advantageous. Furthermore, innovations such as nanoparticle incorporation and chemical derivatization (e.g., carboxymethylation, hydroxypropylation) have expanded their utility in energy devices and smart sensors. Despite these advances, challenges remain in optimizing the energy efficiency of production methods for industrial scalability. This review provides a comprehensive overview of the current state of chitin-based hydrogels, offering insights into future directions for research and development in this promising field. Full article