Search Results (1,217)

The rapid development of digital technology is reshaping the global economic landscape. However, its impact on firms’ capacity utilization rate (CUR), particularly through technological innovation, remains unclear. This study investigates this issue by developing an endogenous growth model that connects digital technology to CUR. The empirical analysis is based on data from Chinese A-share manufacturing firms. The methods employed include quantile regression, instrumental variable techniques, and various tests to explore underlying mechanisms. CUR is calculated using a special model that looks at random variations, and digital transformation is assessed using text analysis powered by machine learning. The findings indicate that digital transformation significantly enhances CUR, especially for firms with average capacity utilization levels, but has a limited effect on low- and high-end firms. Moreover, technological innovation mediates this relationship; however, factors like “double arbitrage” (involving policy and capital markets) and “herd effects” tend to prioritize quantity over quality, which constrains innovation potential. Improvements in CUR lead to enhanced firm performance and productivity, generating industry spillovers and demonstrating the broader economic externalities of digitalization. This study uniquely applies endogenous growth theory to examine the role of digital transformation in optimizing CUR. It introduces the “quantity-quality” technology innovation paradox as a crucial mechanism and highlights industry spillovers to address overcapacity while offering insights for fostering sustainable economic and social development in emerging markets. Full article

This study evaluates the effectiveness of the B Impact Assessment (BIA) as a catalyst for integrating sustainability into industrial firms through a qualitative case study of LC Paper, the first B Corp-certified tissue manufacturer globally and a pioneer in applying BIA in the pulp and paper sector. Based on semi-structured interviews, organizational documents, and direct observation, this study examines how BIA influences corporate governance, environmental practices, and stakeholder engagement. The findings show that BIA fosters structured goal setting and the implementation of measurable actions aligned with environmental stewardship, social responsibility, and economic resilience. Tangible outcomes include improved stakeholder trust, internal transparency, and employee development, while implementation challenges such as resource allocation and procedural complexity are also reported. Although the single-case design limits generalizability, this study identifies mechanisms transferable to other firms, particularly those in environmentally intensive sectors. The case studied also illustrates how leadership commitment, participatory governance, and data-driven tools facilitate the operationalization of sustainability. By integrating stakeholder and institutional theory, this study contributes conceptually to understanding certification frameworks as tools for embedding sustainability. This research offers both theoretical and practical insights into how firms can align strategy and impact, expanding the application of BIA beyond early adopters and into traditional industrial contexts. Full article

This study explores whether sustainability achievements—proxied through ESG (environmental, social, and governance) reporting—are associated with superior financial performance in Latvia’s manufacturing sector, where ESG maturity remains low and institutional readiness is still emerging. Building on stakeholder, legitimacy, signal, slack resources, and agency theories, this study applies a mixed-method approach (that consists of two analytical stages) suited to the limited availability and reliability of ESG-related data in the Latvian manufacturing sector. Financial indicators from three large firms—AS MADARA COSMETICS, AS Latvijas Finieris, and AS Valmiera Glass Grupa—are compared with industry averages over the 2019–2023 period using independent sample T-tests. ESG integration is evaluated through a six-stage conceptual schema ranging from symbolic compliance to performance-driven sustainability. The results show that AS MADARA COSMETICS, which demonstrates advanced ESG integration aligned with international standards, significantly outperforms its industry in all profitability metrics. In contrast, the other two companies remain at earlier ESG maturity stages and show weaker financial performance, with sustainability disclosures limited to general statements and outdated indicators. These findings support the synergy hypothesis in contexts where sustainability is internalized and operationalized, while also highlighting structural constraints—such as resource scarcity and fragmented data—that may limit ESG-financial alignment in post-transition economies. This study offers practical guidance for firms seeking competitive advantage through strategic ESG integration and recommends policy actions to enhance ESG transparency and performance in Latvia, including performance-based reporting mandates, ESG data infrastructure, and regulatory alignment with EU directives. These insights contribute to the growing empirical literature on ESG effectiveness under constrained institutional and economic conditions. Full article

Background: Pain is a complex phenomenon characterized by unpleasant experiences with profound heterogeneity influenced by biological, psychological, and social factors. According to the National Health Interview Survey, 50.2 million U.S. adults (20.5%) experience pain on most days, with the annual cost of prescription medication for pain reaching approximately USD 17.8 billion. Theranostic pain nanomedicine therefore emerges as an attractive analgesic strategy with the potential for increased efficacy, reduced side-effects, and treatment personalization. Theranostic nanomedicine combines drug delivery and diagnostic features, allowing for real-time monitoring of analgesic efficacy in vivo using molecular imaging. However, clinical translation of these nanomedicines are challenging due to complex manufacturing methodologies, lack of standardized quality control, and potentially high costs. Quality by Design (QbD) can navigate these challenges and lead to the development of an optimal pain nanomedicine. Our lab previously reported a macrophage-targeted perfluorocarbon nanoemulsion (PFC NE) that demonstrated analgesic efficacy across multiple rodent pain models in both sexes. Here, we report PFC-free, biphasic nanoemulsions formulated with a biocompatible and non-immunogenic plant-based coconut oil loaded with a COX-2 inhibitor and a clinical-grade, indocyanine green (ICG) near-infrared fluorescent (NIRF) dye for parenteral theranostic analgesic nanomedicine. Methods: Critical process parameters and material attributes were identified through the FMECA (Failure, Modes, Effects, and Criticality Analysis) method and optimized using a 3 × 2 full-factorial design of experiments. We investigated the impact of the oil-to-surfactant ratio (w/w) with three different surfactant systems on the colloidal properties of NE. Small-scale (100 mL) batches were manufactured using sonication and microfluidization, and the final formulation was scaled up to 500 mL with microfluidization. The colloidal stability of NE was assessed using dynamic light scattering (DLS) and drug quantification was conducted through reverse-phase HPLC. An in vitro drug release study was conducted using the dialysis bag method, accompanied by HPLC quantification. The formulation was further evaluated for cell viability, cellular uptake, and COX-2 inhibition in the RAW 264.7 macrophage cell line. Results: Nanoemulsion droplet size increased with a higher oil-to-surfactant ratio (w/w) but was no significant impact by the type of surfactant system used. Thermal cycling and serum stability studies confirmed NE colloidal stability upon exposure to high and low temperatures and biological fluids. We also demonstrated the necessity of a solubilizer for long-term fluorescence stability of ICG. The nanoemulsion showed no cellular toxicity and effectively inhibited PGE2 in activated macrophages. Conclusions: To our knowledge, this is the first instance of a celecoxib-loaded theranostic platform developed using a plant-derived hydrocarbon oil, applying the QbD approach that demonstrated COX-2 inhibition. Full article

Natural fiber-based biocomposites are rapidly gaining traction in sustainable manufacturing. However, their supply chain (SC) designs at the feedstock pre-processing stage often lack robust multicriteria decision-making evaluations, which can impact downstream processes and final product quality. This case study proposes a sustainability-driven multicriteria decision-making framework for selecting pre-processing equipment configurations within a hemp-based biocomposite SC. Using a cradle-to-gate system boundary, four alternative configurations combining balers (square vs. round) and hammer mills (full-screen vs. half-screen) are evaluated. The analytical network process (ANP) model is used to evaluate alternative SC configurations while capturing the interdependencies among environmental, economic, social, and technical sustainability criteria. These criteria are further refined with the inclusion of sub-criteria, resulting in a list of 11 key performance indicators (KPIs). To evaluate ranking robustness, a non-linear programming (NLP)-based sensitivity model is developed, which minimizes the weight perturbations required to trigger rank reversals, using an IPOPT solver. The results indicated that the Half-Round setup provides the most balanced sustainability performance, while Full-Square performs best in economic and environmental terms but ranks lower socially and technically. Also, the ranking was most sensitive to the weight of the system reliability and product quality criteria, with up to a 100% shift being required to change the top choice under the ANP model, indicating strong robustness. Overall, the proposed framework enables decision-makers to incorporate uncertainty, interdependencies, and sustainability-related KPIs into the early-stage SC design of bio-based composite materials. Full article

The rapid proliferation of electronic waste, driven by the short lifecycle of smartphones and planned obsolescence strategies, presents escalating global environmental challenges. To address these issues from a systems perspective, this study develops an agent-based modeling (ABM) framework that simulates consumer decisions and stakeholder interactions within the smartphone reuse and recycling ecosystem. The model incorporates key behavioral drivers—privacy concerns, moral norms, and financial incentives—to examine how social and economic factors shape consumer behavior. Four primary agent types—consumers, manufacturers, recyclers, and second-hand retailers—are modeled to capture complex feedback and market dynamics. Calibrated using empirical data from Jiangsu Province, China, the simulation reveals a dominant consumer tendency to store obsolete smartphones rather than engage in reuse or formal recycling. However, the introduction of government subsidies significantly shifts behavior, doubling participation in second-hand markets and markedly improving recycling rates. These results highlight the value of integrating behavioral insights into environmental modeling to inform circular economy strategies. By offering a flexible and behaviorally grounded simulation tool, this study supports the design of more effective policies for promoting responsible smartphone disposal and lifecycle extension. Full article

Demands for companies to comply with environmental, social, and governance (ESG) requirements are growing, and companies are also expected to play a role in promoting sustainable development. For companies to achieve sustainable growth while addressing ESG, it must be understood whether ESG activities promote improved corporate financial performance. We conducted a five-year panel data analysis of 635 Japanese firms from FY 2019 to FY 2023, using the PBR, PER, and ROE financial indicators as the dependent variables and CSR ratings in the human resource utilization (HR), environment (E), governance (G), and social (S) categories as the independent variables. The results revealed that, depending on the combination of ESG field and financial indicators, companies with advanced ESG initiatives had greater financial performance, with some cases showing a nonlinear relationship; differences in the results between manufacturing and nonmanufacturing industries were also observed. For companies to effectively advance ESG activities, it is important to clarify the objectives and results for each ESG category. For policymakers to consider measures to encourage companies’ ESG activities, it is also important to design finely tuned regulations and incentives according to the ESG category and industry characteristics. Full article

Certain industries will bear a disproportionate share of the burden of climate change. Climate change risk perceptions can impact workers’ mental health and well-being; increased climate change risk perceptions are also associated with more favourable adaptive attitudes. It is, therefore, important to understand whether climate risk perceptions differ across workers between industries. We conducted an online survey of British Columbians (16+) in 2021 using social media advertisements. Participants rated how likely they believed their industry (Natural Resources, Science, Art and Recreation, Education/Law/Government, Health, Management/Business, Manufacturing, Sales, Trades) would be affected by climate change (on a scale from “Very Unlikely” to “Very Likely”). Ordinal logistic regression examined the association between occupational category and perceived industry vulnerability, adjusting for socio-demographic factors. Among 877 participants, 66.1% of Natural Resources workers perceived it was very/somewhat likely that climate change would impact their industry; only those in Science (78.3%) and Art and Recreation (71.4%) occupations had higher percentages. In the adjusted model, compared to Natural Resources workers, respondents in other occupations, including those in Art and Recreation, Education/Law/Government, Management/Business, Manufacturing, Sales, and Trades, perceived significantly lower risk of climate change-related industry impacts. Industry-specific interventions are needed to increase awareness of and readiness for climate adaptation. Policymakers and industry leaders should prioritize sectoral differences when designing interventions to support climate resilience in the workforce. Full article

Packaging waste is a major environmental issue, making the transition to sustainable solutions imperative. This article proposes the concept of Shared Producer Responsibility (SPR) as a key approach to advancing sustainable packaging in the fast-moving consumer goods (FMCG) sector. The study explores how the United Nations Sustainable Development Goals (SDGs), environmental, social, and governance (ESG) reporting, and stakeholder engagement converge to support this transition. The research identifies current trends, challenges, and gaps in sustainable packaging practices through a systematic literature review (SLR) and analysis of sustainability and ESG reports from leading FMCG and packaging companies. The findings highlight the need for standardised reporting frameworks and improved stakeholder cooperation to enhance transparency and accountability in sustainability efforts. This study proposes a conceptual framework for accelerating sustainable packaging adoption through combining strategies like consumer education, regulatory incentives, and clear product labelling. The proposal to implement the concept of Shared Producer Responsibility emphasises the shared accountability of FMCG companies and packaging manufacturers in managing the full environmental lifecycle of packaging materials. This approach is crucial for achieving SDG 12 (responsible consumption and production) and SDG 13 (climate action) and driving more effective and sustainable packaging practices across the FMCG industry. Full article

The 100-Day Mission, coordinated by the Coalition for Epidemic Preparedness Innovations (CEPI) and endorsed by significant international stakeholders, aims to shorten the timeframe for developing and implementing vaccines to 100 days after the report of a new pathogen. This ambitious goal is outlined as an essential first step in improving pandemic preparedness worldwide. This review highlights the mission’s implementation potential and challenges by examining it through the lens of low- and middle-income countries (LMICs), which often face barriers to equitable vaccine access. This article explores the scientific, economic, political, and social aspects that could influence the mission’s success, relying on lessons learned from previous pandemics, such as the Spanish flu, H1N1, and COVID-19. We also examined important cornerstones like prototype vaccine libraries, accelerated clinical trial preparedness, early biomarkers identification, scalable manufacturing capabilities, and rapid pathogen characterization. The review also explores the World Health Organization (WHO) Pandemic Agreement and the significance of Phase 4 surveillance in ensuring vaccine safety. We additionally evaluate societal issues that disproportionately impact LMICs, like vaccine reluctance, health literacy gaps, and digital access limitations. Without intentional attempts to incorporate under-resourced regions into global preparedness frameworks, we argue that the 100-Day Mission carries the risk of exacerbating already-existing disparities. Ultimately, our analysis emphasizes that success will not only rely on a scientific innovation but also on sustained international collaboration, transparent governance, and equitable funding that prioritizes inclusion from the beginning. Full article

Sustainable manufacturing is gaining attention in the scientific literature. However, it remains unclear how to effectively incorporate it within Production Planning and Control (PPC) tasks. All the choices taken in terms of PPC impact sustainability, and sustainability managers and planners or managers involved in tasks, such as scheduling or inventory management, are not conscious of what this means or implies, above all, in terms of the sustainable performance indicators on which their actions can act. While several studies have addressed both PPC and sustainability, there is still limited guidance or structured frameworks specifically aimed at systematically linking PPC tasks with sustainability indicators in a practical and operational industrial context, despite the development of numerous sustainability standards in recent years. For this reason, this research aimed to develop a first detailed framework, specifically based on the Global Reporting Initiative (GRI) standard, that associates the most relevant indicators with the PPC phases, highlighting the type of impact (direct or indirect) of each phase on them. This could help with strategic decisions and promote more informed choices. The overall framework revealed the prevalence of environmental aspects involved in PPC phases (as expected) and a challenge related to the measurability of indicators (above all, the social ones). Furthermore, the Material Requirements Planning (MRP), identified as the most significant phase in terms of its impact on sustainability, was deeply analyzed, providing details related to the decision-making processes of this phase that affect sustainable performance. Full article

Background: Drones are rapidly establishing themselves as one of the most critical technologies. Robotics, automated machinery, intelligent manufacturing, and other high-impact technological research and applications bring up pressing ethical, social, legal, and political issues. Methods: The present research aims to present the results of a qualitative investigation that looked at perceptions of the growing socio-ethical conundrums surrounding the development of drone applications. Results: According to the obtained results, participants often share similar opinions about whether different drone applications are approved by the public, regardless of their level of experience. Perceptions of drone applications appear consistent across various levels of expertise. The most notable associations are with military objectives (73%), civil protection (61%), and passenger transit and medical purposes (56%). Applications that have received high approval include science (8.70), agriculture (8.78), and disaster management (8.87), most likely due to their obvious social benefits and reduced likelihood of ethical challenges. Conclusions: The study’s findings can help shape the debate on drone acceptability in particular contexts, inform future research on promoting value-sensitive development in society more broadly, and guide researchers and decision-makers on the use of drones, as people’s attitudes, understanding, and usage will undoubtedly impact future advancements in this technology. Full article

Employees’ green voice behavior (GVB), as a specific category of extra-role green behavior, plays a vital role in promoting a firm’s sustainable development. However, its underlying mechanism has not been sufficiently explored. Drawing on social learning theory (SLT), this study proposes a research model that examines the indirect influence of environmentally-specific transformational leadership (ESTFL) on GVB via psychological empowerment (PE) and ecological reflexivity (ER) as well as the moderating role of person-supervisor value congruence (PSVC). To achieve the research goals, we conducted a two-wave online survey via the convenience sampling method to collect data from 530 employees and 106 direct supervisors working in the manufacturing, hospitality and service, energy production, construction, transportation, information and communication, and finance industries in China. Regression analyses and CFA based on SPSS and Mplus were employed to test and validate the research model. Our findings show that PE and ER both partially mediated the positive association between ESTFL and GVB. Moreover, PSVC moderated the mediating effects of ESTFL on GVB via PE and ER. This study advances empirical research regarding how leadership impacts GVB by revealing dual cognitive mechanisms and identifying its boundary condition. It also offers managerial implications for leaders and enterprises in China to promote employees’ GVB and improve sustainable management. Full article

Human Factors and Ergonomics (HF/E) play an essential role in the development of sustainable manufacturing systems. By prioritizing worker wellbeing through the mitigation of occupational hazards and the enhancement of workplace health, HF/E contributes significantly to improved system performance. In accordance with the principles of Industry 5.0 and Society 5.0, which emphasize human-centered design and wellbeing, organizations that effectively integrate HF/E principles can achieve a competitive advantage on the market. Based on a globally recognized ranking system utilized by investors in making informed decisions, the study focuses on manufacturing companies ranked by their occupational health and safety (OHS) scores, a key criterion for assessing the social dimension of company performance. This research aims to identify and analyze top-ranked companies that explicitly highlight HF/E-related benefits within their public documents and sustainability reports. The paper investigates aspects related to the integration of AI and digital technologies to enhance safety and health in manufacturing systems, with a specific focus on human presence detection in hazardous zones, improvements in machines and equipment design, occupational risk assessments, and initiatives for enhancing worker wellbeing. The findings are expected to provide compelling evidence for companies to prioritize HF/E consideration during the design and redesign phases of sustainable manufacturing systems. The paper provides significant value to non-indexed companies by offering a dual approach for improving OHS performance, based on an empirical evaluation assessment method and practical strategies for effective OHS implementation in different manufacturing industries and countries. Full article

This article presents a comparative analysis of digital manufacturing laboratories (DMLs) in Mexico and Spain. It is argued that DMLs, also known as makerspaces or FabLabs, play a key role in innovation and experimentation, but that their success depends on the relationships they establish with social actors, such as local governments, universities, and firms. Key concepts of the transformative innovation approach such as “protective space” and “embeddedness” are introduced, which allow us to understand how DMLs operate within a complex system. The comparative analysis of a DML in Mexico City (Mexico) and a DML in Valencia (Spain) allows us to identify similarities and differences in their operational contexts. While the Mexican DML faces a lack of government support and dependence on the private sector, the Spanish one benefits from strong institutional support and public policies that facilitate its development. This results in greater stability and capacity for action for the Valencian FabLab VLC compared to the Mexican FabLab Finally, we reflect on how the embeddedness received from different social actors affects the autonomy and transformative capacity of DMLs, suggesting that while both labs have the potential to innovate, their contexts and relationships determine their effectiveness and sustainability in the digital sociotechnical system. Full article