Search Results (2,921)

Mycotoxins are fungal secondary metabolites with dual significance: they threaten health via food contamination yet hold potential as biopesticides. Their isolation from complex matrices remains a critical challenge. This review analyzes classical methods (liquid–liquid extraction, SPE including QuEChERS, chromatography). Traditional techniques suffer from poor selectivity, multi-step processing, large toxic solvent volumes, and matrix effects. As alternatives, emerging strategies based on rational design are considered: directed cocrystallization, supercritical fluid extraction, smart MOF/COF membranes, and AI integrated with physicochemical modeling. The concept of “precision” extraction enabling prediction of target isolation at the molecular level is developed. Recommendations for standardizing experimental reporting to create machine-readable datasets for neural networks are provided. The review concludes that while most still require experimental validation for mycotoxins, these approaches point toward selective, sustainable mycotoxin isolation technologies for analytical control and pure standard production. Full article

Heterogeneous fault information and a lack of real-time synchronization in CNC machine tools hinder effective Prognostics and Health Management (PHM). This paper designs and implements a digital twin-driven PHM framework for machine tools that integrates a unified machine-tool fault information dictionary and a mechanism-data dual-driven diagnostic model (ResNet-TCN). A cyber–physical platform was developed using OPC UA and RESTful APIs to ensure real-time data synchronization. Experiments on the PHM 2010 dataset demonstrate that the proposed ResNet-TCN model achieves a root mean square error (RMSE) of 5.46 μm for tool wear prediction. Its performance surpasses that of traditional LSTM models, and the proposed framework effectively eliminates information silos, providing a responsive, scalable and accurate PHM solution for smart manufacturing. Full article

With increasing constraints on extensive farming—including soil degradation, salinisation and more frequent climatic anomalies—the development of ‘smart’ agriculture requires the integration of affordable, non-invasive methods for monitoring the physiological state of plants. A key indicator for assessing productivity and the early detection of stress is the rate of photosynthetic CO₂ assimilation (A); however, widely available commercial gas analysers are characterised by high cost, technical complexity and considerable weight, which limits their use in large-scale field studies. Here, a new handheld system for measuring assimilation was developed and tested, based on the accumulative principle of recording changes in CO₂ concentration using simple infrared sensors and without maintaining a constant air flow around the leaf. A comparison was carried out between a prototype of the developed system and a commercial gas analyser when measuring leaf assimilation under irrigation and simulated drought conditions. The results demonstrated the consistency of the readings from the two systems. The developed system is characterised by its compact size, low cost, and the absence of moving parts and consumables. The proposed system has the potential to be effective for large-scale screening tasks and rapid diagnosis of stress-induced changes; it represents a promising, affordable tool for addressing applied tasks in precision agriculture, environmental monitoring and physiological research. Full article

Smart contact lens sensors integrate biochemical sensing elements, flexible electronics, power modules, and wireless readout components onto optically transparent contact lens platforms, enabling non-invasive and potentially continuous analysis of tear-derived biomarkers and ocular physiological signals. This review focuses on the translation pathway from contact lens materials and fabrication methods to sensing mechanisms, tear biomarker interpretation, and clinical deployment. We synthesize recent progress in substrate engineering, manufacturing processes, power delivery, and representative sensing strategies for intraocular pressure, glucose, electrolytes, pH, cortisol, cholesterol, and inflammatory cytokines. Instead of treating these systems as isolated examples, we compare optical/colorimetric, electrochemical, field-effect transistor, microfluidic, and wireless resonant approaches in terms of sensitivity, response time, power/readout requirements, and clinical relevance. Finally, we discuss persistent barriers, including biocompatibility, interface stability, tear-sample variability, calibration, sterilization, regulatory validation, data privacy, and compatibility with commercial contact lens manufacturing. Full article

Low back pain (LBP) is a major global health problem and can result in a variety of movement impairments. Advances in smart technology have enabled the collection of novel streams of movement data, and machine learning (ML) methods have been increasingly used for data analysis. However, many existing technologies remain expensive and unsuitable for widespread clinical use, and ML approaches have largely focused on distinguishing people with LBP from healthy controls rather than identifying meaningful subgroups within the LBP population. Motion Tape (MT) is a recently developed wearable strain sensor that translates skin deformation from underlying movement and muscle engagement into electrical signals. In this exploratory study involving 10 participants with LBP, we demonstrate that MT data from six sensors applied on the lower back capture rich movement information capable of characterizing movement patterns among participants with LBP. We propose a feature engineering approach based on biomechanical features as well as time-series causal discovery applied to multivariate sensor time-series data to extract directed inter-segment coordination patterns. We further develop an exploratory subgroup discovery pipeline by aggregating clustering coassociation information across diverse movement tasks. Our causal coordination features show promising discriminative information across several movement types, capturing aspects of motor control not reflected in amplitude-based or embedding-based features alone, such as asymmetries and movement restrictions. Preliminary ensemble clustering analysis indicates three potential LBP subgroups distinguished by biomechanical and inter-segment coordination patterns, which may reflect varied strategies under different movement demands. We investigate the differences in clinical characteristics among these LBP subgroups. We show that time-series foundation models are not well suited for LBP subgrouping due to their uninterpretability, which is improved in our feature engineering pipeline. This framework could reveal additional subgroups with larger cohorts and may generalize to other sensor modalities. Full article

Mobile health (mHealth) systems in rural communities require rigorous software engineering methodology and empirical validation of end-user acceptance. A gap exists in applying structured System Development Life Cycle (SDLC) frameworks to community-facing mHealth platforms with embedded technology acceptance evaluation. This study presents the design, architecture, and iterative development of the “Smart Daily Life Care” cross-platform mobile application using a six-phase SDLC framework, targeting rural elderly communities in Thailand. The system architecture employed a microservices design with age-friendly UI engineering, conforming to WCAG 2.1 AA. Technology acceptance was evaluated post-deployment using the Technology Acceptance Model (TAM) with 200 participants (elderly users, caregivers, and health personnel). System efficiency was rated at $\overline{\mathrm{x}}$ = 4.58 and user satisfaction at $\overline{\mathrm{x}}$ = 4.64. TAM regression identified perceived usefulness as the dominant predictor of behavioral intention (β = 0.412), followed by perceived ease of use (β = 0.318) and social influence (β = 0.268), with R² = 0.682. Integrating TAM evaluation within SDLC phases enables iterative remediation of acceptance barriers before deployment. Village Health Volunteer networks function as indispensable sociotechnical enablers of adoption. The SDLC–TAM integration provides a structured methodological approach suitable for replication in age-sensitive health information systems in low-resource settings. Full article

Digital twin technology is becoming a core enabler for the intelligent transformation of civil engineering. This review adopts an integrated mixed-method design that combines a reproducible bibliometric protocol with structured content analysis to connect macro-level knowledge evolution with domain-specific engineering implementation. Based on the Web of Science Core Collection, the study analyzes publication trends, collaboration patterns, highly cited studies, keyword co-occurrence, network centrality, and citation bursts, and then reviews application status and technical pathways across five thematic areas: intelligent construction, bridge engineering, tunnel engineering, smart water conservancy, and other infrastructure. Key findings include: rapid growth in publication volume after 2021, three dominant keyword clusters (model/system construction, structural health monitoring and sensing, and AI-enabled optimization/decision-making), and an evolution of research frontiers from concept introduction to engineering scenario deepening and further to three-dimensional reconstruction, knowledge fusion, and intelligent decision-making. The content analysis shows differentiated technical pathways across sub-domains and identifies data heterogeneity/interoperability as the most urgent bottleneck because it constrains model updating, cross-platform integration, and engineering-scale deployment. Future directions should focus on data standardization, hybrid modeling, platform interoperability, artificial intelligence empowerment, and full-lifecycle cross-system coordination. This review provides a quantitatively supported panoramic reference for digital twin research in civil engineering. Full article

To address the issues of insufficient real-time performance and inadequate modeling of temporal features in traffic police gesture recognition, this paper proposes a method based on skeleton keypoints and hybrid temporal modeling. First, YOLOv11m-Pose is employed to detect human skeleton keypoints in video sequences, extracting reliable two-dimensional skeleton features. Second, this study designs a temporal modeling network that integrates a bidirectional long short-term memory (BiLSTM) with a Transformer. The BiLSTM models local temporal continuity and action transition features between adjacent frames, capturing short-term dynamic changes. The Transformer, through its self-attention mechanism, models global temporal dependencies and weights critical time steps to extract long-range discriminative information. Experimental results demonstrate that the proposed method achieved 98.91% for both Accuracy and F1-Score. In terms of Accuracy, it outperformed the BiLSTM and Transformer models by 2.43% and 7.67%, respectively. It outperforms most methods based on recurrent neural networks and feature fusion. Meanwhile, the model achieves an average inference time of just 1.3299 s per gesture sequence. Consequently, this approach strikes a favorable balance between recognition accuracy and real-time performance, demonstrating significant practical value. Full article

Nano-/microplastics (NMPs) accumulation in agricultural soils has become a growing environmental concern due to its negative impacts on soil health, crop productivity, and food safety. Biochar has gained considerable attention as a sustainable soil amendment capable of improving soil quality and mitigating emerging pollutants. This review examines the role of biochar and modified biochar in reducing the mobility, bioavailability, and plant uptake of NMPs through adsorption, aggregation, and immobilization mechanisms. In addition, biochar improves soil fertility by enhancing nutrient retention, water holding capacity, soil structure, and microbial activity, while also contributing to climate change mitigation through carbon sequestration. However, certain biochars may negatively affect saline–alkaline soils because of their high pH and salinity. Generally, biochar application offers multiple environmental benefits, including soil restoration, pollutant mitigation, and enhanced agricultural sustainability. This review synthesizes recent advances in understanding the mechanisms by which biochar influences NMPs behavior in soil–plant systems and highlights current knowledge gaps and future research directions needed to support its effective application in sustainable agriculture. Full article

In this paper, we propose a self-learning digital twin (SLDT) architecture that incorporates real-time battery degradation modeling and optimum operational management for grid-scale lithium-ion battery energy storage systems (BESS). This work extends the Adaptive Real-Time Degradation Model (ARDM) framework to allow real-time updates of the parameters based only on live operational data without pre-cycling experiments and further improves its robustness under various depth-of-discharge (DoD), charging/discharging current (C-rate), and temperature conditions. The ARDM is incorporated in a real-time digital twin that maintains synchronized health, state of charge (SoC), and degradation cost predictions. The digital twin is linked to an Optimization and Control Layer (OCL), which plans the charge/discharge day-ahead in advance based on dynamic power rates. The Musical Chairs Algorithm (MCA) is used for parameter identification and scheduling due to its better convergence characteristics compared to swarm-reduction forms of benchmark optimization algorithms. Experimental validation is carried out on two commercial 48 V Li-ion modules with various cycling patterns, and sub-millipercent root-mean-square error (RMSE) is achieved in capacity-fade tracking. The economic analysis for a 5-MW/10-MWh system indicates that dynamic tariff scheduling results in about nine times greater arbitrage revenue compared to fixed rates, 41–58% higher yearly net income, and lower degradation costs. The results confirm that the SLDT is a practical and accurate platform for degradation-aware operational planning in modern smart-grid environments. Full article

Maintaining good indoor air quality (IAQ) is essential for student health, cognitive performance, and overall well-being. Traditional ventilation strategies, particularly constant air volume systems and manual window operation, often fail to maintain optimal IAQ while simultaneously increasing building energy consumption. In response, smart ventilation systems have emerged as a promising alternative capable of dynamically modulating airflow based on occupancy patterns and real-time pollutant levels. This study presents a systematic review of fourteen carefully selected peer-reviewed studies (2015–2025) that represent the most recent and methodologically robust research on smart ventilation applications in school environments across diverse climatic conditions. The selected studies encompass experimental, simulation-based, and hybrid methodologies, and classify control strategies into demand-controlled, temperature-adaptive, occupancy-based, AI-enhanced, and building management system (BMS)-integrated approaches. Collectively, the findings demonstrate measurable improvements in IAQ indicators (e.g., carbon dioxide (CO₂), particulate matter (PM_2.5), ozone (O₃), and volatile organic compounds (VOCs)) and significant energy savings, in some cases exceeding 60%, while also identifying system vulnerabilities such as fault sensitivity, short monitoring durations, and limited long-term validation. Importantly, the review reveals critical geographic and climatic research gaps, particularly in hot–arid regions where ventilation-related cooling demand is substantial, as well as limited long-term assessments in cold climates. Furthermore, although smart ventilation systems perform effectively under controlled conditions, insufficient real-world verification, user interaction analysis, and climate-specific optimization constrain broader implementation. Addressing these gaps through climate-dependent performance evaluation and long-term operational studies is essential to unlocking the full potential of smart ventilation systems in delivering healthier, energy-efficient classrooms. Full article

Background: Childhood obesity is a complex public health issue in which parental perceptions and family dietary behaviors are pivotal. This study assessed the feasibility of the Smart Family lifestyle counseling intervention in Greek primary care. It explored changes in children’s dietary behaviors relative to parental weight perception and Mediterranean diet adherence. Methods: A single-arm pretest–posttest pilot study was conducted in Patras, Greece, from Health4EUKids Joint Action. The intervention consisted of four monthly face-to-face counseling sessions using the Smart Family methodology. In total, 49 parent–child dyads (aged 2–12 years) completed the program. Data collection included child anthropometric measurements, validated food frequency questionnaires, parental perception of child weight status, and parental Mediterranean diet adherence. Results: Parents who underestimated their child’s weight status had significantly higher Mediterranean diet scores than those who overestimated (p = 0.032); those with low adherence tended to overestimate and those with moderate adherence to underestimate. The largest reduction was observed for sweets and desserts (median −2.35 servings/week), with significant reductions in sugar-sweetened beverages, grains and cereals, whole wheat products, and dairy. Fish and vegetable intake increased significantly, but fruit intake did not change. Changes in fast food and red meat differed significantly across Mediterranean diet score tertiles, with larger decreases in the lower tertiles. Conclusions: Smart Family counseling was feasible to deliver through trained healthcare professionals in Greek primary care over four months, with reductions in selected discretionary foods observed alongside the intervention. Parental weight perception and Mediterranean diet adherence emerged as potential barriers to change although the findings are exploratory and require confirmation in a future controlled trial. Full article

Functional brain networks in schizophrenia (SZ) are often characterized by covariance-based measures, yet covariance matrices live on a curved geometric structure rather than in ordinary Euclidean space, complicating noise-robust inference from scalp EEG. We develop a Riemannian Geometry-based Adaptive Nonlinear Coupling Analysis (RGA-NCA) framework that integrates the affine-invariant Riemannian metric (AIRM), tangent space mapping (TSM), and an anatomically adaptive artifact rejection (AAAR) strategy accounting for regional signal-to-noise heterogeneity. The framework is grounded in the observation that Euclidean summaries of symmetric positive definite matrices are sensitive to noise-driven volume inflation, whereas geodesic distances on the manifold emphasize shape deformation. RGA-NCA was evaluated on four benchmark dynamical systems, a supplementary multichannel EEG-like sample covariance simulation, and a public button-tone SZ/HC EEG dataset associated with the auditory feedback paradigm described by Ford et al. (81 subjects; 49 SZ, 32 healthy controls). Compared with Euclidean and linear baselines, RGA-NCA showed lower sensitivity to noise-driven distance distortion and yielded clearer group-level contrasts in the tested ROI analyses; all four pre-specified frontotemporal and parietal channel pairs remained significant after Benjamini–Hochberg FDR correction. The resulting patterns are consistent with reduced long-range connectivity together with localized hyper-synchronization-like effects in SZ. Quantitatively, the Riemannian structural sensitivity index $(\mathrm{sim}=\exp (-d^2/4))$ remained high across all tested SNR levels (−20 to +10 dB; 50 Monte Carlo trials per level; range 0.936–0.964), with only a 0.026 endpoint change between +10 and −20 dB, whereas the Euclidean metric fell from 0.922 at +10 dB to 0.000 at −20 dB. These findings support Riemannian modeling as a candidate strategy for noisy covariance-based neural data, pending validation in larger independent cohorts. Full article

Timely fish disease monitoring is an important requirement for sustainable aquaculture because disease outbreaks can reduce survival, increase treatment inputs, and destabilise production. In aquaponic systems, fish health is also linked to nutrient cycling and the stability of integrated fish–vegetable production, making automated fish-health perception a potentially useful component of resource-efficient farming. Existing classification and detection methods can identify disease categories or approximate lesion locations, but they provide limited information about lesion area, boundary shape, and severity-related spatial extent. This study presents a deep learning framework for pixel-level fish lesion segmentation to support sustainable aquaculture health monitoring, with aquaponic systems considered as a potential application context. The framework combines lesion-preserving frequency augmentation (LPFA), confidence-guided large-kernel encoding (CGLE), and confidence-filtered decoder refinement (CFDR). LPFA expands lesion appearance variation during training while retaining the main lesion layout. CGLE uses coarse prediction confidence to allocate broader contextual modelling to uncertain encoder regions, and CFDR applies selective decoder correction to low-confidence regions. A public freshwater fish disease dataset is reformulated into a dense prediction task with 1750 raw images from seven image-level categories, including six disease categories and one normal healthy category. The images are divided into training, validation, and test subsets at an 8:1:1 ratio, and controlled augmentation strategies are applied online rather than being used to create a larger static dataset. Across five random-seed runs, the proposed method achieves $82.6\pm 0.3$% mIoU, $90.9\pm 0.2$% mDice, and $73.5\pm 0.4$% Boundary IoU. Relative to TransUNet, the mean mIoU rises from $78.4\pm 0.4$% to $82.6\pm 0.3$%, and Boundary IoU rises from $68.8\pm 0.5$% to $73.5\pm 0.4$%, with paired bootstrap testing supporting the stability of the improvement. These results indicate its potential as a lesion-quantification decision-support component for smart and sustainable fish-production systems. Full article

Background: Managing occupational stress in healthcare services is critical because frontline workers operate under multiple job demands. Objective: We extend the literature on health psychology and organizational behavior by examining how two types of occupational stress—eustress and psychological distress—impact the performance of frontline healthcare service workers. We also investigate the interactive influence of stress management strategies—savoring and avoidance coping—on the performance effects of occupational stress. Methods: We surveyed 400 frontline healthcare service workers across the globe using MTurk. We used Smart PLS4 to assess our measures and test our hypotheses. Results: Job demands—a higher-order construct comprising workload, role conflict, and work complexity—had a non-significant effect on eustress (β = 0.037, p = 0.596) but a significant positive effect on psychological distress (β = 0.566, p < 0.001). Eustress had a positive effect on employee engagement (β = 0.229, p < 0.001) and savoring (β = 0.437, p < 0.001). Psychological distress had a positive effect on turnover intention (β = 0.275, p < 0.001) and avoidance coping (β = 0.525, p < 0.001). The interaction between savoring and eustress had a negative effect on employee engagement (β = −0.162, p = 0.003). The interaction between avoidance coping and psychological distress had a negative effect on turnover intention (β = −0.058, p = 0.054). Conclusions: Job demands in frontline healthcare services manifest as hindrance stressors that increase workers’ psychological distress. Avoidance coping is an effective strategy for managing psychological distress and reducing workers’ turnover intention. Full article