Search Results (5,518)

Amidst Hölderlin’s many well-known odes, elegies, and hymns, it is perhaps not surprising that Hölderlin’s occasional poem “To my Venerable Grandmother. On her 72nd Birthday” (Meiner verehrungswürdigen Grosmutter. Zu ihrem 72sten Geburtstag) has been translated into English only once and in an obscure self-published edition. Yet the poem is rich in Hölderlin’s distinctive diction and syntax, it reveals much about Hölderlin’s aspirations for himself, and it contains one of his deepest sets of reflections on Christ. Still, the poem is often overlooked. But once one reflects on its content, with its multiple attempts to name Christ, including his friendship to the earth and his knowing no strangers, one can readily see why Pope Francis elevated this poem as one of his favorite literary works. This publication presents the first accessible translation of the poem (I), after which I offer some commentary on its form, individual lines, and the translation (II). I then turn to the period of his writing the poem (III). I conclude with a few additional thoughts on Hölderlin and religion (IV). Full article

Background/Objectives: Obesity among university students is a growing concern, often influenced by biological, psychological, and social factors. Few studies in Saudi Arabia have addressed this issue using a comprehensive framework. This study aims to examine the prevalence of obesity and its biopsychosocial predictors among university students, as well as their perceptions, behaviors, and comorbidities. Methods: A cross-sectional study was conducted at Jazan University during the 2024–2025 academic year. A total of 819 undergraduate students completed a structured, self-administered Arabic questionnaire. The tool assessed sociodemographic variables, body mass index (BMI) (calculated from self-reported height and weight), biological and psychological factors, social influences, lifestyle behaviors, and comorbidities. Bivariate associations were tested using chi-square analyses, and multivariate logistic regression was used to identify independent predictors of obesity. Results: The prevalence of obesity was 19.6%, and 22.6% of students were overweight. Obesity was significantly more prevalent among males (26.7%) than females (9.6%, p < 0.001) and among students aged 24 years and above (24.0%, p = 0.024). Independent predictors of obesity included being overweight in childhood (AOR = 5.23, 95% CI: 3.47–7.90), belief in a genetic predisposition (AOR = 4.66), emotional eating (AOR = 2.57), academic or personal stress (AOR = 5.36), and social pressures related to body image (AOR = 2.96). Comorbidities significantly associated with obesity included high cholesterol (AOR = 5.40), sleep disorders (AOR = 2.99), and joint pain (AOR = 1.96). More than 80% of students with obesity reported current or past weight loss attempts, and nearly 60% received medical advice to lose weight. Conclusions: Obesity among Jazan University students is significantly associated with male gender, early-life weight history, emotional and academic stress, and social pressures. Students with obesity also experience a higher burden of comorbid conditions, even at a young age. These findings highlight the need for integrated, student-centered interventions that address both the psychological and social dimensions of weight management in university settings. Full article

Background: This study aims to evaluate the cost-effectiveness of providing the 23-valent pneumococcal polysaccharide vaccine (PPV23) free of charge versus self-paying vaccination among adults aged 60 years and older in Nanning, Guangxi, China. Methods: A decision tree–Markov model was developed to compare three strategies (government-funded free vaccination, self-funded vaccination, and no vaccination) over a 5-year time horizon. The model incorporated local epidemiological data and cost parameters, applying a 3% discount rate. Sensitivity analyses were conducted on key parameters, including vaccine effectiveness against pneumonia and pneumonia treatment costs. Results: The benefit–cost ratios for free and self-funded vaccination were 0.075 and 0.015, respectively, both below the cost-effectiveness threshold of 1. However, the free vaccination strategy resulted in a higher net benefit (USD 399,651.32) compared to the self-funded strategy (USD 222,594.14), along with a lower Incremental Cost-Effectiveness Ratio (ICER) (USD 1.47 per USD 0.14 of avoided disease cost). Although both strategies yielded benefit–cost ratios far below the conventional threshold of 1, the free strategy demonstrated relatively greater economic efficiency. Sensitivity analyses confirmed that vaccine effectiveness against pneumonia and treatment costs were key drivers of economic outcomes. Conclusions: While neither vaccination strategy achieved conventional cost-effectiveness benchmarks in this setting, the free PPV23 vaccination program demonstrated relatively greater economic efficiency compared to the self-funded approach; although neither strategy met the conventional cost-effectiveness thresholds, they should be considered for inclusion in regional health policy for older adults. Full article

Background: Non-medical use of prescription stimulants is increasing among college students worldwide. While intended for ADHD treatment, many students use these substances to improve their concentration and academic performance. Despite global research, little is known about the psychological and attitudinal factors influencing such use in the Israeli academic context. Objectives: We wished to examine the relationship between self-efficacy, attitudes toward stimulant use, and actual use among Israeli college students, aiming to uncover the mechanisms behind non-medical stimulant consumption. Methods: A cross-sectional online survey was conducted among 598 students from two Israeli academic institutions. The participants completed validated questionnaires assessing their demographic characteristics, stimulant use patterns, self-efficacy, and attitudes. Results: A total of 22% of students reported using stimulants, 17% of them without a prescription. Positive attitudes significantly increased the likelihood of use (Exp(B) = 3.31, p < 0.001), while higher self-efficacy reduced it (Exp(B) = 0.69, p < 0.01). A negative correlation was found between self-efficacy and favorable attitudes (r = −0.17, p < 0.001). The mediation analysis revealed that self-efficacy influences stimulant use entirely through its effect on attitudes toward stimulants. Additionally, stimulant use was significantly more common among Jewish students (25%) compared to non-Jewish students (11%; p < 0.05) and among smokers (36%) compared to non-smokers (20%; p < 0.001). Conclusions: Positive attitudes and low self-efficacy are key risk factors for stimulant misuse. These findings underscore the need for educational interventions aimed at strengthening self-efficacy and promoting healthier coping strategies in academic settings. Full article

(1) Background: Physical activity (PA) is a key modifiable risk factor for chronic diseases, yet many adults do not meet PA guidelines. Just-in-time adaptive interventions (JITAIs), a type of mobile health (mHealth) intervention, offer tailored support based on an individual’s context to promote PA. Integrating behavior change techniques (BCTs) and theories is critical to the design of effective mHealth interventions. Understanding which BCTs and theories work best can inform future JITAI development. (2) Objective: The objective of this study is to examine how behavior change theories and BCTs are implemented in mHealth PA JITAIs and assess their relationship with PA-related outcomes. (3) Methods: This scoping review followed the PRISMA-ScR guidelines. A total of 29 studies were included. (4) Results: The most commonly used BCTs include prompts/cues (n = 29), goal-setting (behavior) (n = 15), and feedback on behavior (n = 14), while self-determination theory (n = 4) and social cognitive theory (n = 4) are the most commonly used theories. However, there is insufficient evidence as to which theories and BCTs are most effective in eliciting effective PA behavior change. (5) Conclusions: Clearer reporting and integration of BCTs and behavior change theories, along with optimized user interfaces, are needed to improve the intervention quality, replicability, and long-term effectiveness of PA JITAIs. Full article

Beef production in Greece is a sector that has been characterized by a decline in both the output and the number of beef-producing animals over the last decades. The major challenge is low beef self-sufficiency; only 19.1% of demand is met by domestic production. The latter leads to a growing reliance on imports of both live animals and carcasses. Hence, the fattening of young bulls from dairy breeds could be an option to address this challenge subject to improving the quality of produced meat. The objective of the present study was to investigate the effects of extruded linseed in the diet of young bulls on their performance and meat quality. Sixty-eight young Holstein bulls were equally assigned in two experimental groups: the control group (CON, n = 34) and Linseed Group (LS, n = 34). Bulls in the CON group received a basal total mixed ration while LS young bulls were offered the same basal ration supplemented with linseed (5% on dry matter basis) during the final fattening stage. All bulls were subjected to three individual weightings at the beginning, the middle and the end of the trial. The feed offered was recorded daily and feed refusals were weighed for each pen to calculate feed intake. After slaughter, the Longissimus dorsi muscle from each carcass was collected to evaluate meat pH, color, chemical composition, tenderness and fatty acid profile. Analysis of variance was used to evaluate the effect of dietary intervention on performance and examined meat parameters, with significance set at p < 0.05, using SPSS software (version 29.0). Average daily gain, dry matter intake and feed conversion ratio were not affected by the dietary intervention (p > 0.05). Similarly, carcass yield and dressing percentage remained unaffected (p > 0.05). Adding extruded linseed did not result in differences in meat quality traits (p > 0.05), except for meat pH, which was significantly decreased in the LS group (p < 0.05), indicating more efficient post-mortem glycolysis. Finally, the inclusion of extruded linseed resulted in higher levels of α-linolenic acid in the meat (p < 0.05). These results suggest that including 5% extruded linseed (on a DM basis) in the diet of young Holstein bulls increased meat n-3 content, improved beef pH and maintained production performance. Full article

The circadian clock is a self-sustaining oscillator with a period of approximately 24 h, enabling organisms to anticipate daily recurring events, such as sunrise and sunset. Since the circadian period is not exactly 24 h and the environmental day length varies throughout the year, the clock must be periodically reset to align an organism’s physiology with the natural light/dark cycle. This synchronization, known as entrainment, is primarily regulated by nocturnal light, which can be replicated in laboratory settings using a 15 min light pulse (LP) and by assessing locomotor activity. An LP during the early part of the dark phase delays the onset of locomotor activity, resulting in a phase delay, whereas an LP in the late dark phase advances activity onset, causing a phase advance. The clock gene Period 2 (Per2) plays a key role in this process. To investigate its contributions, we examined the effects of Per2 deletion in neurons versus astrocytes using glia-specific GPer2 (Per2/GfapCre) knockout (KO) and neuronal-specific NPer2KO (Per2/NesCre) mice. All groups were subjected to Aschoff type II protocol, where an LP was applied at ZT14 or ZT22 and the animals were released into constant darkness. As control, no LP was applied. Phase shift, period, amplitude, total activity count, and rhythm instability were assessed. Our findings revealed that mice lacking Per2 in neurons (NPer2) exhibited smaller phase delays and larger phase advances compared to control animals. In contrast, mice with Per2 deletion specifically in glial cells including astrocytes (GPer2) displayed normal clock resetting. Interestingly, the absence of Per2 in either of the cell types resulted in a shorter circadian period compared to control animals. These results suggest that astrocytic Per2 is important for maintaining the circadian period but is not required for phase adaptation to light stimuli. Full article

The wild tomato (Solanum sisymbriifolium) is a globally distributed shrubby weed with both negative and positive impacts, including its invasive properties and the potential for pharmaceutical and traditional medicinal uses. Despite its ecological significance, the plant’s reproductive biology and pollination ecology remain poorly understood. This study aimed to investigate the floral biology, pollination ecology, and plant reproduction of the weed species. Some flower traits, such as flowering intensity, flower display size, and pollen and ovule production, peaked during spring, summer, and the monsoon, while flower longevity and stigmatic receptivity were the longest in winter. The plant species was self-compatible (ISI = 0.02), heavily depended on pollinators (IDP = 0.72), and experienced minimal pollination limitation (D = 0.10) under open-pollination conditions. Flower visitors’ traits (e.g., abundance, diversity, and richness) were higher in the spring, summer, and the monsoon, and these were lower in winter. The vital pollination service was provided by Amegilla zonata, Ceratina binghami, Lasioglossum cavernifrons, Nomia (Curvinomia) strigata, Tetragonula pagdeni, Xylocopa aestuans, Xylocopa amethystina, Xylocopa fenestrata, and Xylocopa latipes. Reproductive success, as indicated by fruit and seed set, varied seasonally, being higher during the spring–monsoon period and lower in winter. These findings support effective management of this weed species and help conserve the associated bee populations. Full article

To solve the issue that existing yield prediction methods do not fully capture the interaction between multiple factors, we propose a winter wheat yield prediction framework with triple cross-attention for multi-source data fusion. This framework consists of three modules: a multi-source data processing module, a multi-source feature fusion module, and a yield prediction module. The multi-source data processing module collects satellite, climate, and soil data based on the winter wheat planting range, and constructs a multi-source feature sequence set by combining statistical data. The multi-source feature fusion module first extracts deeper-level feature information based on the characteristics of different data, and then performs multi-source feature fusion through a triple cross-attention fusion mechanism. The encoder part in the production prediction module adds a graph attention mechanism, forming a dual branch with the original multi-head self-attention mechanism to ensure the capture of global dependencies while enhancing the preservation of local feature information. The decoder section generates the final predicted output. The results show that: (1) Using 2021 and 2022 as test sets, the mean absolute error of our method is 385.99 kg/hm², and the root mean squared error is 501.94 kg/hm², which is lower than other methods. (2) It can be concluded that the jointing-heading stage (March to April) is the most crucial period affecting winter wheat production. (3) It is evident that our model has the ability to predict the final winter wheat yield nearly a month in advance. Full article

Background/Objectives: This prospective intervention study examined the learning effect of using 3D-printed phantom heads with cleft lip and palate (CLP) and upper jaw models with CLP and maxillary plates during a lecture for dental students in their fourth year at J. W. Goethe Frankfurt University. The primary aim was to evaluate the impact of 3D-printed models on students’ satisfaction levels along with their understanding and knowledge in dental education. Methods: Six life-sized phantom heads with removable mandibles (three with unilateral and three with bilateral CLP) were designed using ZBrush software (Pixologic Inc., Los Angeles, CA, USA) based on MRI images and printed with an Asiga Pro 4K 3D printer (Asiga, Sydney, Australia). Two groups of students (n = 81) participated in this study: the control (CTR) group (n = 39) attended a standard lecture on cleft lip and palate, while the intervention (INT) group (n = 42) participated in a hands-on seminar with the same theoretical content, supplemented by 3D-printed models. Before and after the session, students completed self-assessment questionnaires and a multiple-choice test to evaluate knowledge improvement. Data analysis was conducted using the chi-square test for individual questions and the Wilcoxon rank test for knowledge gain, with the significance level set at 0.05. Results: The study demonstrated a significant knowledge increase in both groups following the lecture (p < 0.001). Similarly, there were significant differences in students’ self-assessments before and after the session (p < 0.001). The knowledge gain in the INT group regarding the anatomical features of unilateral cleft lip and palate was significantly higher compared to that in the CTR group (p < 0.05). Conclusions: The results of this study demonstrate the measurable added value of using 3D-printed models in dental education, particularly in enhancing students’ understanding of the anatomy of cleft lip and palate. Full article

The TOWCHED project explores how arts and heritage-based educational methodologies can support sustainable development by enhancing key transversal competencies in learners, particularly children and youth. In response to the global challenges outlined in the sustainable development goals (SDGs), this project promotes inclusive and participatory approaches to education that foster social cohesion, intercultural understanding, and civic engagement. Partnering with museums, TOWCHED develops cross-curricular pedagogical interventions, such as experiential, blended, and collection-mediated learning, that link cultural heritage with contemporary social and environmental concerns. These approaches aim to strengthen creativity, critical thinking, collaboration, and self-awareness. TOWCHED demonstrates that heritage collection-based education can play a vital role in transforming schools and other learning environments into hubs for sustainable, lifelong learning. By embedding cultural expression and heritage into educational practices, the project offers a compelling model for empowering individuals to navigate and shape a more equitable and interconnected world. This paper has two aims. First, we introduce TOWCHED, an interdisciplinary project recently funded by the Horizon Europe program of the European Union to preserve and promote education for sustainability in the heritage context. Second, we introduce a set of tools related to the project. Full article

Heart rate variability (HRV), particularly the root mean square of successive differences (RMSSD), is widely used as a non-invasive indicator of autonomic nervous system activity and physiological recovery. This study examined whether daily short-term HRV, measured under standardised morning conditions, was associated with self-reported wellness in a non-clinical adult population. Over a 14-day period, 41 participants completed daily five-minute HRV recordings using a Polar H10 chest sensor and the Kubios mobile app, followed by ratings of sleep quality, fatigue, stress, and physical recovery. Bayesian ordinal mixed-effects models revealed that higher RMSSD values were associated with better self-reported sleep (β = 0.510, 95% HDI: 0.239 to 0.779), lower fatigue (β = 0.281, 95% HDI: 0.020 to 0.562), and reduced stress (β = 0.353, 95% HDI: 0.059 to 0.606), even after adjusting for covariates. No association was found between RMSSD and perceived muscle soreness. These findings support the interpretability of RMSSD as a physiological marker of daily recovery and stress in real-world settings. While the effect sizes were modest and individual variability remained substantial, results suggest that consistent HRV monitoring may offer meaningful insight into subjective wellness—particularly when contextualised and tracked over time. Full article

Reinforcement learning (RL), a branch of artificial intelligence (AI), is becoming more popular in a variety of application fields such as games, workplaces, and behavioral analysis, due to its ability to model complex decision-making through interaction and feedback. Traditional systems for personality and behavior assessment often rely on self-reported questionnaires, which are prone to bias and manipulation. RL offers a compelling alternative by generating diverse, objective behavioral data through agent–environment interactions. In this paper, we propose a Reinforcement Learning-based framework in a game environment, where agents simulate personality-driven behavior using context-aware policies and exhibit a wide range of realistic actions. Our method, which is based on the OCEAN Five personality model—openness, conscientiousness, extroversion, agreeableness, and neuroticism—relates psychological profiles to in-game decision-making patterns. The agents are allowed to operate in numerous environments, observe behaviors that were modeled using another simulation system (HiDAC) and develop the skills needed to navigate and complete tasks. As a result, we are able to identify the personality types and team configurations that have the greatest effects on task performance and collaboration effectiveness. Using interaction data derived from self-play, we investigate the relationships between behaviors motivated by the personalities of the agents, communication styles, and team outcomes. The results demonstrate that in addition to having an effect on performance, personality-aware agents provide a solid methodology for producing realistic behavioral data, developing adaptive NPCs, and evaluating team-based scenarios in challenging settings. Full article

Background: This article introduces the development and application of a life review program designed to support the psychological well-being of middle-aged and older adults living with HIV. Grounded in Swanson’s Theory of Caring, the program emphasizes culturally sensitive, narrative-based reflection and group sharing. Methods: This study employed a qualitative exploratory design, implementing an eight-week life review program based on Swanson’s Theory of Caring. Data were collected through in-depth interviews and participant observations and then analyzed using qualitative content analysis. Results: Thematic analysis revealed that participants experienced emotional engagement, renewed self-understanding, and a sense of connection fostered by the caring-based narrative process. Participants also expressed positive attitudes toward reinterpreting their past and envisioning the future. Conclusions: Rather than evaluating intervention outcomes, this study focuses on the development and implementation of a caring-based life review tool. Findings illustrate its feasibility and cultural acceptability, offering a foundation for future adaptation across diverse supportive care settings. This culturally sensitive intervention represents one of the first applications of a caring-based life review program tailored to aging PLWHIV in Taiwan. Full article

This study responds to the urgent need for education that fosters sustainable, self-directed development by introducing a five-phase narrative instruction pre-module grounded within the Life Design Thinking (LDT) framework. Integrating design thinking with narrative theory, LDT promotes learner agency, identity coherence, and adaptive future planning through structured autobiographical reflection. The intervention was conducted in a group setting with 14 adult learners (n = 14) from China. Although participant demographics were not the primary focus, the study emphasized theoretical and methodological development through iterative instructional design. A mixed-methods approach was employed, including rubric-based scoring of 101 written narratives and a thematic analysis of the reflective content. The results demonstrated significant improvements in narrative competence, especially in technical application (+80.91%), reflective depth (+70.0%), with thematic clarity (+58.11%), also showing notable gains related to meaning synthesis and narrative focus. Learners also exhibited enhanced thematic continuity and future-oriented integration. These outcomes highlight the value of narrative pedagogy as a transformative learning approach aligned with SDG 4.7. By cultivating metacognitive awareness and future-readiness, the module contributes to education for sustainable development and provides initial evidence for a potentially scalable and transferable model that supports learners in navigating complexity with meaning and purpose. Full article