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  • Article
  • Open Access
12 Citations
3,401 Views
9 Pages

Fractures of the Craniofacial Skeleton in the Elderly: Retrospective Studies

  • Piotr Michalak,
  • Grażyna Wyszyńska-Pawelec,
  • Mariusz Szuta,
  • Justyna Hajto-Bryk,
  • Jan Zapała and
  • Joanna Katarzyna Zarzecka

The aim of the retrospective analysis of the medical documentation of 101 patients was to assess the incidence, etiology, and type of craniofacial fractures in the elderly population of southern Poland, who required specialist treatment at the Depart...

(This article belongs to the Special Issue Oral Health in the Elderly)
  • Review
  • Open Access
3 Citations
3,780 Views
10 Pages

4 September 2025

Asthma and chronic rhinosinusitis (CRS) are prevalent chronic inflammatory conditions of the airways that frequently occur together, contributing to increased disease burden and reduced quality of life. This study aimed to synthesize findings from re...

  • Article
  • Open Access
6 Citations
4,131 Views
10 Pages

Prognostic Factors in Endodontic Surgery Using an Endoscope: A 1 Year Retrospective Cohort Study

  • Shintaro Sukegawa,
  • Rieko Shimizu,
  • Yuka Sukegawa,
  • Kazuaki Hasegawa,
  • Sawako Ono,
  • Ai Fujimura,
  • Izumi Yamamoto,
  • Keisuke Nakano,
  • Kiyofumi Takabatake and
  • Yoshihiko Furuki
  • + 2 authors

7 May 2022

This retrospective study clarified the success rate of endoscopic endodontic surgeries and identified predictors accounting for successful surgeries. In this retrospective study, 242 patients (90 males, 152 females) who underwent endoscopic endodonti...

(This article belongs to the Special Issue Materials for Hard Tissue Repair and Regeneration (Second Volume))
  • Article
  • Open Access
10 Citations
6,270 Views
7 Pages

Association between Height and Hypertension: A Retrospective Study

  • Yuji Shimizu,
  • Hidenobu Hayakawa,
  • Nagisa Sasaki,
  • Midori Takada,
  • Takeo Okada and
  • Masahiko Kiyama

25 July 2022

Height loss starting in middle age is reported to be an independent risk factor for cardiovascular mortality. Recent studies have revealed an inverse association between height and hypertension, but the influence of hypertension on height loss is unk...

  • Article
  • Open Access
10 Citations
2,241 Views
12 Pages

29 October 2022

Fractures of the femoral neck are one of the most common reasons for admission to an orthopedic institute. These patients also show multimorbidity (≥2 chronic conditions) and polytherapy (≥5 drugs). Multimorbidity and polytherapy are associated with...

(This article belongs to the Section Orthopedics)
  • Article
  • Open Access
10 Citations
5,217 Views
9 Pages

In the Department of Parasitology and Mycology of Toulouse University Hospitals, patients presenting with common/covert toxocariasis were treated either with albendazole (39 cases) or with diethylcarbamazine (32 cases). Albendazole (ABZ) was given at...

(This article belongs to the Special Issue Bacterial, Fungal and Parasitic Zoonoses)
  • Article
  • Open Access
6 Citations
5,253 Views
10 Pages

The Pattern of Tooth Loss for Periodontally Favorable Teeth: A Retrospective Study

  • Peter Yanni,
  • Donald A. Curtis,
  • Richard T. Kao and
  • Guo-Hao Lin

15 November 2022

To retrospectively analyze local and systemic factors that resulted in the short-term tooth loss of teeth that were previously assigned a favorable prognosis in patients who were seen and treated over an observational five-year period. This retrospec...

  • Proceeding Paper
  • Open Access
3 Citations
6,815 Views
9 Pages

Background and Objectives: Mortality rates among patients with rheumatoid arthritis (RA) have been reported to be higher than in the general population. The long-term prognosis of RA has improved in recent years due to early diagnosis, as well as eff...

(This article belongs to the Proceedings of The 1st International Electronic Conference on Medicine)
  • Article
  • Open Access
343 Views
11 Pages

Post-COVID-19 Thyroid Function Changes in Primary Care: A Retrospective Observational Study

  • Dorota Szydlarska,
  • Marta Zuzanna Ciechomska,
  • Andrzej Śliwczyński,
  • Alicja Jakubowska,
  • Waldemar Wierzba and
  • Olga Maguza

15 September 2026

Background: Coronavirus disease 2019 (COVID-19) has been associated with thyroid dysfunction; however, evidence from primary care settings remains limited. Given that most patients with COVID-19 are managed outside hospital settings, understanding th...

  • Article
  • Open Access
10 Citations
2,726 Views
14 Pages

The Impact of the First Wave of the COVID-19 Pandemic on Healthcare Workers: An Italian Retrospective Study

  • Giuliana Buresti,
  • Bruna Maria Rondinone,
  • Diana Gagliardi,
  • Marta Petyx,
  • Fortunato Paolo D’Ancona,
  • Patrizio Pezzotti,
  • Flavia Riccardo and
  • Sergio Iavicoli

Healthcare workers (HCWs) played an essential role in managing the COVID-19 pandemic. The Italian Workers’ Compensation Authority (INAIL) and the Italian National Institute of Health (ISS) developed a retrospective study to analyze and understa...

  • Article
  • Open Access
1,030 Views
15 Pages

11 October 2025

Background/Objectives: This retrospective study aimed to evaluate the survival and marginal bone loss (MBL) of sloped-shoulder implants placed in the posterior mandible, and to explore the influence of both patient- and implant-related factors. Mater...

(This article belongs to the Special Issue Innovations and Challenges in Dental Implantology)
  • Article
  • Open Access
784 Views
14 Pages

Depressive Symptoms in Pediatric Tuberculosis: A Retrospective Two-Time-Point Observational Study

  • Oana Mariana Mihailov,
  • Loredana Stavăr Matei,
  • George Țocu,
  • Valerii Luțenco,
  • Cosmin George Popovici and
  • Raul Mihailov

29 April 2026

Background: Tuberculosis (TB) in children is associated not only with infectious burden but also with potential psychological distress, which remains insufficiently explored. The aim of this study was to evaluate the pattern and evolution of depressi...

(This article belongs to the Special Issue Mental Health—Management and Care, Multidisciplinary Approaches and Perspectives)
  • Article
  • Open Access
8 Citations
3,701 Views
19 Pages

Phase 4 Multinational Multicenter Retrospective and Prospective Real-World Study of Nivolumab in Recurrent and Metastatic Squamous Cell Carcinoma of the Head and Neck

  • Anagha Gogate,
  • Bryan Bennett,
  • Zia Poonja,
  • Grant Stewart,
  • Ana Medina Colmenero,
  • Petr Szturz,
  • Courtney Carrington,
  • Clara Castro,
  • Eric Gemmen and
  • Robert Metcalf
  • + 10 authors

9 July 2023

This study examined the real-world use of nivolumab in patients with recurrent/metastatic squamous cell carcinoma of the head and neck (R/M SCCHN). This was a multinational retrospective study (VOLUME) assessing treatment effectiveness and safety out...

(This article belongs to the Special Issue Targeted Immunotherapies for Cancers)
  • Article
  • Open Access
431 Views
15 Pages

20 August 2026

Background: Trigeminal neuralgia is a chronic neuropathic pain disorder characterized by severe recurrent facial pain and substantial impairment in quality of life. Although microvascular decompression (MVD) is an established surgical treatment for m...

(This article belongs to the Special Issue The Evolving Landscape of Trigeminal Neuralgia: From Bench to Bedside and Beyond)
  • Article
  • Open Access
5 Citations
4,736 Views
10 Pages

Injuries (unintentional and intentional) are the main cause of death and disability worldwide, including Jordan. The main purpose of this hospital-based retrospective study was to identify characteristics, causes, and risk factors of unintentional in...

(This article belongs to the Section Global Health)
  • Article
  • Open Access
12 Citations
8,430 Views
19 Pages

Uterine Carcinosarcoma (UCS): A Literature Review and Survival Analysis from a Retrospective Cohort Study

  • Mauro Francesco Pio Maiorano,
  • Gennaro Cormio,
  • Brigida Anna Maiorano and
  • Vera Loizzi

21 November 2024

Background/Objectives: Uterine carcinosarcomas (UCSs) are rare and aggressive malignancies with limited epidemiological data. This study aims to evaluate the clinical and pathological features and prognostic factors of UCS in a retrospective cohort o...

(This article belongs to the Section Molecular Cancer Biology)
  • Article
  • Open Access
10 Citations
3,778 Views
8 Pages

Radiation-induced mucositis in head and neck cancer patients generates difficulties in eating and swallowing, and may influence treatment tolerance, compliance, and quality of life. However, predictive factors have not been studied in detail. Thus, t...

(This article belongs to the Special Issue State-of-the-Art Cancer Biology, Biodiagnostics and Therapeutics in Japan)
  • Article
  • Open Access
12 Citations
4,011 Views
10 Pages

Risk Factors for Macrosomia in Multipara: A Multi-Center Retrospective Study

  • Juan Juan,
  • Yumei Wei,
  • Geng Song,
  • Rina Su,
  • Xu Chen,
  • Ruiqin Shan,
  • Jianying Yan,
  • Mei Xiao,
  • Ying Li and
  • Huixia Yang
  • + 12 authors

The increased incidence of macrosomia has caused an enormous burden after the transition from the almost 40-year one-child policy to the universal two-child policy in 2015 and further to the three-child policy in 2021 in China. However, studies on ri...

(This article belongs to the Special Issue New Research in Neonatal-Perinatal Medicine)
  • Article
  • Open Access
6 Citations
4,532 Views
14 Pages

Frequency of Breakfast, Lunch, and Dinner and Incidence of Proteinuria: A Retrospective Cohort Study

  • Ryohei Tomi,
  • Ryohei Yamamoto,
  • Maki Shinzawa,
  • Yoshiki Kimura,
  • Yoshiyuki Fujii,
  • Katsunori Aoki,
  • Shingo Ozaki,
  • Ryuichi Yoshimura,
  • Manabu Taneike and
  • Toshiki Moriyama
  • + 5 authors

19 November 2020

Although multiple studies have revealed a close association of skipping breakfast with cardiometabolic diseases, few studies have reported its association with chronic kidney disease (CKD). Furthermore, there is scant reporting on the clinical impact...

(This article belongs to the Section Nutritional Epidemiology)
  • Article
  • Open Access
10 Citations
8,195 Views
10 Pages

Colorectal cancer (CRC) is a common disease and one of the leading causes of cancer deaths worldwide. This retrospective cohort study evaluated the risk of developing CRC in people with hemorrhoids. Using Taiwan’s National Health Insurance Research D...

(This article belongs to the Section Public Health Statistics and Risk Assessment)
  • Article
  • Open Access
2 Citations
2,682 Views
9 Pages

Breakfast Frequency and Smoking Initiation in University Students: A Retrospective Cohort Study

  • Rika Mori,
  • Ryohei Yamamoto,
  • Maki Shinzawa,
  • Naoko Otsuki,
  • Yuichiro Matsumura,
  • Yuko Nakamura,
  • Qinyan Li,
  • Yusuke Sakaguchi,
  • Isao Matsui and
  • Izumi Nagatomo
  • + 5 authors

21 July 2024

Smoking causes various health problems. Limited studies have reported a clinical effect of skipping breakfast on smoking initiation among adolescents. This retrospective cohort study aimed to assess the dose-dependent association between skipping bre...

(This article belongs to the Section Nutritional Policies and Education for Health Promotion)
  • Article
  • Open Access
378 Views
12 Pages

Clinical Performance of Infrazygomatic Crest Miniscrews Placed Without Surgical Guides: A Retrospective Study with 30-Month Follow-Up

  • Gianna Dipalma,
  • Alessio Danilo Inchingolo,
  • Maral Di Giulio Cesare,
  • Sharon Di Serio,
  • Marialuisa Longo,
  • Francesco Inchingolo,
  • Marco Severino,
  • Ioana Roxana Bordea,
  • Grazia Marinelli and
  • Angelo Michele Inchingolo

Background: Infrazygomatic crest (IZC) miniscrews provide reliable extra-alveolar skeletal anchorage for orthodontic tooth movement while minimizing dependence on patient compliance. Although guided insertion techniques have been proposed to improve...

(This article belongs to the Section Biomedical Engineering and Biomaterials)
  • Article
  • Open Access
2 Citations
2,069 Views
14 Pages

Is Serum 25-Hydroxyvitamin D Level Associated with Severity of COVID-19? A Retrospective Study

  • Munachimso Kizito Mbata,
  • Mireille Hunziker,
  • Anja Makhdoomi,
  • Giorgia Lüthi-Corridori,
  • Maria Boesing,
  • Stéphanie Giezendanner,
  • Jürgen Muser,
  • Anne B. Leuppi-Taegtmeyer and
  • Jörg D. Leuppi

25 August 2023

(1) Background: SARS-COV2 infection has a clinical spectrum ranging from asymptomatic infection to COVID-19 with acute respiratory distress syndrome (ARDS). Although vitamin D deficiency is often found in patients with ARDS, its role in COVID-19 is n...

(This article belongs to the Section Infectious Diseases)
  • Article
  • Open Access
16 Citations
10,494 Views
10 Pages

Association between Cervical Spondylosis and Migraine: A Nationwide Retrospective Cohort Study

  • Wang-Sheng Lin,
  • Tung-Fu Huang,
  • Tien-Yow Chuang,
  • Cheng-Li Lin and
  • Chia-Hung Kao

Background: Few studies have investigated the longitudinal association between cervical spondylosis (CS) and migraine by using a nationwide population-based database. Methods: We conducted a retrospective cohort study from 2000 to 2011 identifying 27...

  • Article
  • Open Access
5 Citations
4,525 Views
10 Pages

Association between Statin Use and Sepsis Risk in Patients with Dementia: A Retrospective Cohort Study

  • Liang-Tsai Yeh,
  • Chuan-Yi Tang,
  • Shun-Fa Yang,
  • Han-Wei Yeh,
  • Ying-Tung Yeh,
  • Yu-Hsun Wang,
  • Ming-Chih Chou,
  • Chao-Bin Yeh and
  • Chi-Ho Chan

This study investigated the association of statin use with sepsis risk in patients with dementia. This retrospective cohort study was conducted in Taiwan by using data from the National Health Insurance Research Database. We identified and enrolled 3...

(This article belongs to the Special Issue Healthcare Infections and Prevention )
  • Article
  • Open Access
4 Citations
4,386 Views
30 Pages

A Retrospective Study of CBCT-Based Detection of Endodontic Failures and Periapical Lesions in a Romanian Cohort

  • Oana Andreea Diaconu,
  • Lelia Mihaela Gheorghiță,
  • Anca Gabriela Gheorghe,
  • Mihaela Jana Țuculină,
  • Maria Cristina Munteanu,
  • Cătălina Alexandra Iacov,
  • Virginia Maria Rădulescu,
  • Mihaela Ionescu,
  • Adina Andreea Mirea and
  • Carina Alexandra Bănică

9 September 2025

Background and Objectives: Cone Beam Computed Tomography (CBCT) offers high-resolution, three-dimensional imaging for detecting apical periodontitis (AP) and evaluating the technical quality of endodontic treatments. This study aimed to investigate t...

(This article belongs to the Special Issue Oral Health in Children: Clinical Management)
  • Article
  • Open Access
6 Citations
3,051 Views
11 Pages

The Efficacy and Tolerability of Electroconvulsive Therapy in Psychiatric Patients with Arachnoid Cysts: A Retrospective Chart Study

  • Ying Lu,
  • Yu Tian,
  • Yu Gan,
  • Yixiao Fu,
  • Qibin Chen,
  • Lei Zou,
  • Bangshu Zhao,
  • Yu Yan,
  • Shudong Liu and
  • Xiao Li
  • + 1 author

15 October 2022

Electroconvulsive therapy (ECT) is an effective therapy for many psychiatric illnesses. However, intracranial occupying lesions are a relative contraindication to ECT. Arachnoid cysts are benign, congenital, and space-occupying lesions. Our study aim...

(This article belongs to the Section Neuropsychiatry)
  • Article
  • Open Access
2 Citations
11,070 Views
10 Pages

Liver Disease Is a Risk Factor for Recurrent Hyperkalemia: A Retrospective Cohort Study

  • Rebecca S. Ahdoot,
  • Jui-Ting Hsiung,
  • Abiy Agiro,
  • Yasmin G. Brahmbhatt,
  • Kerry Cooper,
  • Souhiela Fawaz,
  • Laura Westfall,
  • Kamyar Kalantar-Zadeh and
  • Elani Streja

8 July 2023

Liver disease is often associated with dysfunctional potassium homeostasis but is not a well-established risk factor for hyperkalemia. This retrospective cohort study examined the potential relationship between liver disease and recurrent hyperkalemi...

(This article belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
  • Article
  • Open Access
12 Citations
5,004 Views
11 Pages

Stroke patients presenting with anemia at the time of stroke onset had a higher risk of mortality and development of other cardiovascular diseases and comorbidities. The association between the severity of anemia and the risk of developing a stroke i...

(This article belongs to the Special Issue 2nd Edition: Frontiers in Health Care for Older Adults)
  • Article
  • Open Access
8 Citations
4,258 Views
13 Pages

Relationship between Oral Health Status and Postoperative Fever among Patients with Lung Cancer Treated by Surgery: A Retrospective Cohort Study

  • Chieko Itohara,
  • Yuhei Matsuda,
  • Yuka Sukegawa-Takahashi,
  • Shintaro Sukegawa,
  • Yoshihiko Furuki and
  • Takahiro Kanno

16 October 2020

A retrospective observational study using an oral bacteria counter was conducted to evaluate the trends in the number of oral bacteria in the perioperative period of lung cancer patients and to verify the relationship between oral health status and p...

(This article belongs to the Special Issue Oral and Maxillofacial Health Care)
  • Article
  • Open Access
2,016 Views
18 Pages

Integrative Analysis of Biochemical, Hormonal, and Histopathological Profiles in Thyroid Nodules: A Seven-Year Retrospective Study

  • Sergiu-Ciprian Matei,
  • Mervat Matei,
  • Sorin Ursoniu,
  • Anna Laura Maiozzi,
  • Ana Silvia Corlan,
  • Bianca Roxana Natarâş,
  • Flavia Medana Petrașcu,
  • Mihaela Maria Vlad,
  • Diana Szekely and
  • Cristina Stefania Dumitru
  • + 1 author

Background/Objectives: Thyroid nodules exhibit substantial histopathological variability, and systemic markers that differentiate benign from malignant patterns remain poorly defined. This study evaluated clinical, biochemical, hormonal, and histopat...

(This article belongs to the Special Issue State-of-the-Art Endocrine Cancer Biology and Oncology)
  • Article
  • Open Access
1 Citations
2,554 Views
17 Pages

Pain Treatment in Primary Care Through Eight Constitution Medicine: A Retrospective Real-World Study from South Korea

  • Nahyun Cho,
  • Younkuk Choi,
  • Heekyung Kim,
  • Jeongmi Yun,
  • Hyungsun Jun,
  • Changsop Yang,
  • Sungha Kim and
  • Jungtae Leem

30 August 2025

Background and Objectives: Musculoskeletal pain is a global public health issue. Eight Constitution Medicine (ECM), a type of East Asian Traditional Medicine, offers personalized, minimally invasive treatment through Eight Constitution Acupuncture (E...

(This article belongs to the Special Issue Advances in Rheumatic and Musculoskeletal Diseases and Health Promotion)
  • Article
  • Open Access
207 Views
12 Pages

Leprosy in Sonora, Mexico: A 14-Year Retrospective Study of Clinical, Epidemiological, and Sociodemographic Characteristics

  • Eliezer Emmanuel Preciado Gocobachi,
  • Miguel Alberto Salgado Salomón,
  • Gonzalo Armando Navarro Armendariz,
  • Sergio Trujillo López,
  • Sayil Alejandra De la Torre Othón,
  • Jurgen Adam Sánchez,
  • Gerardo Álvarez Hernández and
  • Jorge Laureano Eugenio

Leprosy remains a public health challenge due to delayed diagnosis, disability, and persistent transmission despite the availability of effective treatment. This study aimed to describe the sociodemographic, clinical, and epidemiological profile of l...

(This article belongs to the Section Neglected and Emerging Tropical Diseases)
  • Article
  • Open Access
443 Views
12 Pages

Root Canal Treatment After Fixed Prosthodontic Restorations: A Retrospective Observational Study

  • Ebru Arslan,
  • Ceren Gedikli Cengiz,
  • Ibrahim Atakan Cengiz,
  • Selim Erkut and
  • Kamran Gulsahi

6 July 2026

Background/Objectives: Root canal treatment (RCT) may be required after full-coverage crown placement in initially vital teeth due to biological and restorative factors affecting pulp vitality. However, the timing and distribution of clinical variabl...

(This article belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
  • Article
  • Open Access
3 Citations
2,246 Views
17 Pages

Priapism Presentations in a Saudi Arabian Emergency Department: A Retrospective Study at a Tertiary Care Hospital

  • Baraa Alghalyini,
  • Abdul Rehman Zia Zaidi,
  • Kanza Atif,
  • Noorah Mosharraf,
  • Hala Tamim and
  • Muhammad Nauman Qureshi

28 August 2024

Objectives: To examine the distribution, clinical characteristics, and management of priapism in a Saudi Arabian tertiary care setting to provide a regional perspective. Subjects and Methods: This retrospective chart review included 29 male patients...

  • Article
  • Open Access
9 Citations
3,829 Views
12 Pages

Relationship between Oral Bacterial Count and Postoperative Complications among Patients with Cardiovascular Disease Treated by Surgery: A Retrospective Cohort Study

  • Rie Osako,
  • Yuhei Matsuda,
  • Chieko Itohara,
  • Yuka Sukegawa-Takahashi,
  • Shintaro Sukegawa,
  • Satoe Okuma,
  • Yoshihiko Furuki and
  • Takahiro Kanno

In this retrospective observational study, we evaluated the relationship between perioperative oral bacterial counts and postoperative complications in cardiovascular disease (CVD) patients. From April 2012 to December 2018, all patients scheduled fo...

(This article belongs to the Special Issue Oral and Maxillofacial Health Care Ⅱ)
  • Article
  • Open Access
5 Citations
4,001 Views
19 Pages

Evaluating Cetuximab Regimens in Head and Neck Cancer: Insights from a Retrospective Cohort Study

  • Chih-Chun Wang,
  • Shyh-An Yeh,
  • Wen-Hui Chen,
  • Hung-Ju Li,
  • Chuan-Chien Yang,
  • Tse-Jen Huang and
  • Yu-Chieh Su

10 January 2025

Background/Objectives: The aim of this study is to assess the effectiveness of cetuximab combination therapy in patients with recurrent or metastatic head and neck cancer treated at a hospital in Southern Taiwan. Methods: This study analyzed a retros...

(This article belongs to the Section Cancer Therapy)
  • Article
  • Open Access
928 Views
14 Pages

Absence of Tendon Reflexes as a Predictor of Diabetic Retinopathy: A Retrospective Cohort Study in Japan

  • Taichi Muramatsu,
  • Ayaka Sugiura,
  • Daisuke Yamamuro,
  • Ryosuke Kumazawa,
  • Manabu Akazawa,
  • Akifumi Kushiyama and
  • Takako Kikuchi

Background/Objective: This study investigated the association between tendon reflexes (Achilles and patellar) and the development of diabetic retinopathy (DR) in patients with type 2 diabetes (T2D). Methods: This single-center retrospective cohort st...

(This article belongs to the Special Issue New Perspectives and Future Challenges in Diabetic Retinopathy)
  • Article
  • Open Access
6 Citations
2,494 Views
10 Pages

Is Intermittent Abdominal Pressure Ventilation Still Relevant? A Multicenter Retrospective Pilot Study

  • Valeria Volpi,
  • Eleonora Volpato,
  • Elena Compalati,
  • Paola Pierucci,
  • Antonello Nicolini,
  • Agata Lax,
  • Laura Fagetti,
  • Anna Annunziata,
  • Rosa Cauteruccio and
  • Paolo Banfi
  • + 1 author

23 March 2023

Non-invasive ventilatory support (NVS) is a technique used to reduce respiratory work in neuromuscular diseases, preventing the progression of respiratory failure. NVS is usually administered via a nasal or an oronasal mask, causing discomfort, espec...

(This article belongs to the Section Clinical Neurology)
  • Article
  • Open Access
418 Views
12 Pages

COVID-19 and Unplanned Paediatric Hospital Readmissions in Australia: A Retrospective Cohort Study

  • Huma Sadulla,
  • Adhya Miriam Tom,
  • Gary Low,
  • Anthony Liu and
  • Habib Bhurawala

Background: Unplanned paediatric hospital readmissions are key indicators of healthcare quality, often reflecting issues in discharge planning and continuity of care. The COVID-19 pandemic significantly disrupted healthcare delivery and utilisation,...

(This article belongs to the Section Health Care Sciences)
  • Article
  • Open Access
382 Views
13 Pages

30 July 2026

Nanostructured calcium-incorporated titanium dental implants have demonstrated favorable biological activity in preclinical studies; however, supporting clinical evidence remains limited. This retrospective cross-sectional study evaluated the surviva...

(This article belongs to the Section Applied Dentistry and Oral Sciences)
  • Article
  • Open Access
1 Citations
5,087 Views
8 Pages

Treatment of Fractures of the Humeral Surgical Neck: MIROS Versus Intramedullary Nailing—A Retrospective Study

  • Michelangelo Palco,
  • Gabriele Giuca,
  • Domenico Fenga,
  • Ilaria Sanzarello,
  • Matteo Nanni and
  • Danilo Leonetti

This retrospective study compares the clinical outcomes of the Minimally Invasive Reduction and Osteosynthesis System (MIROS) and intramedullary nailing (IMN) in treating isolated surgical neck fractures of the humerus. A total of 42 patients were in...

  • Article
  • Open Access
2 Citations
770 Views
13 Pages

A Retrospective Chart Review Study on the Burden of Illness of Acid Sphingomyelinase Deficiency in Brazil

  • Roberto Giugliani,
  • Ana Cecília Menezes de Siqueira,
  • Ana Maria Martins,
  • Bianca Fernandes Marcondes,
  • Carolina Fischinger Moura de Souza,
  • Dafne Dain Gandelman Horovitz,
  • Emília Katiane Embiruçu Leão,
  • Gaelle Gusto,
  • Gerson da Silva Carvalho and
  • Gerasimos Konidaris
  • + 4 authors

12 January 2026

Background: Acid sphingomyelinase deficiency (ASMD) is a rare, progressive lysosomal storage disease with heterogeneous clinical manifestations. Evidence on the disease burden of ASMD is limited in Brazil. Methods: This observational, multicenter, re...

(This article belongs to the Section Clinical Pediatrics)
  • Article
  • Open Access
23 Citations
5,638 Views
8 Pages

Steroid-Sparing Effect of Tocilizumab and Methotrexate in Patients with Polymyalgia Rheumatica: A Retrospective Cohort Study

  • Keisuke Izumi,
  • Okinori Murata,
  • Misako Higashida-Konishi,
  • Yuko Kaneko,
  • Hisaji Oshima and
  • Tsutomu Takeuchi

30 June 2021

Polymyalgia rheumatica (PMR) is an inflammatory disorder characterized by pain and stiffness in the shoulders, hips, and proximal limbs; it usually affects elderly patients. The effectiveness of methotrexate and tocilizumab in PMR treatment has not b...

(This article belongs to the Section Immunology & Rheumatology)
  • Article
  • Open Access
6 Citations
2,822 Views
9 Pages

Colorectal Cancer Risk in Women with Gynecologic Cancers—A Population Retrospective Cohort Study

  • Szu-Chia Liao,
  • Hong-Zen Yeh,
  • Chi-Sen Chang,
  • Wei-Chih Chen,
  • Chih-Hsin Muo and
  • Fung-Chang Sung

15 July 2021

We conducted a retrospective cohort study to evaluate the subsequent colorectal cancer (CRC) risk for women with gynecologic malignancy using insurance claims data of Taiwan. We identified patients who survived cervical cancer (N = 25,370), endometri...

(This article belongs to the Special Issue Gastrointestinal Malignancies: Screening, Diagnosis, and Treatment)
  • Article
  • Open Access
125 Views
20 Pages

11 October 2026

Molidustat, an oral hypoxia-inducible factor prolyl hydroxylase inhibitor, is approved for nonregenerative anemia associated with chronic kidney disease (CKD) in cats but is also used for anemia of other causes. This retrospective, single-center stud...

(This article belongs to the Section Veterinary Internal Medicine)
  • Article
  • Open Access
5 Citations
3,746 Views
12 Pages

Emerging and re-emerging parasitic diseases can cause significant economic burdens at national and global levels. However, governments often underestimate or ignore these diseases, especially in developed countries. This retrospective, case-oriented...

(This article belongs to the Special Issue Parasite Infection and Tropical Infectious Diseases)
  • Article
  • Open Access
313 Views
17 Pages

Radiographic Changes in Patellar Height Following Rapid Weight Loss After Sleeve Gastrectomy: A Retrospective Observational Study

  • Emre Erdoğan,
  • Elif Nur Gencer,
  • Furkan Türkoğlu,
  • Ahmet Çulcu,
  • Soner Sarı and
  • Özgür Doğan

14 September 2026

Background/Objectives: Rapid weight loss following sleeve gastrectomy substantially reduces mechanical loading across the lower extremities, yet its effects on patellar height remain unknown. This study investigated early postoperative radiographic c...

(This article belongs to the Special Issue Bariatric Surgery: Current Status and Emerging Clinical Trends)
  • Article
  • Open Access
6 Citations
5,269 Views
11 Pages

Association between Proton Pump Inhibitor Use and CNS Infection Risk: A Retrospective Cohort Study

  • Wei-Te Hung,
  • Ying-Hock Teng,
  • Shun-Fa Yang,
  • Han-Wei Yeh,
  • Ying-Tung Yeh,
  • Yu-Hsun Wang,
  • Ming-Yung Chou,
  • Ming-Chih Chou,
  • Chi-Ho Chan and
  • Chao-Bin Yeh

31 August 2018

This study investigated the incidence of central nervous system (CNS) infection following the use of proton pump inhibitors (PPIs). A retrospective cohort study was conducted in Taiwan by using data from the National Health Insurance Research Databas...

(This article belongs to the Section Clinical Neurology)
  • Article
  • Open Access
1 Citations
4,359 Views
17 Pages

Association Between Nursing Diagnoses and Mortality in Hospitalized Patients with COVID-19: A Retrospective Cohort Study

  • José Ángel Hernández-Mariano,
  • Olivia Mendoza-Macario,
  • María del Carmen Velázquez-Núñez,
  • María del Carmen Cedillo-Ordaz,
  • Blanca Estela Cervantes-Guzmán,
  • Dulce Milagros Razo-Blanco-Hernández,
  • Erick Alberto Landeros-Olvera,
  • Fani Villa-Rivas,
  • Rocío Castillo-Díaz and
  • Guillermo Cano-Verdugo

28 April 2025

Previous studies suggest that nursing diagnoses (NDs) could predict clinical outcomes, such as mortality, among patients with non-communicable diseases. However, evidence in patients with COVID-19 is still scarce. Objective: To evaluate the associati...

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