Search Results (39)

(1) Background: As the demand for ²¹²Pb for clinical theranostics rises, empirical studies that examine the radiation safety implications of different ²²⁴Ra sources are needed to facilitate discussions with local authorities for the translation of ^203/212Pb theranostics routine clinical practice. (2) Methods: Environmental ²²⁰Rn (Thoron) emanation was detected by a RAD7 detector in the vicinity of respective ²¹²Pb sources and additional alpha-dosimeters to detect ²²⁰Rn during generator elution, radiosynthesis, and quality control. Personnel gamma exposure was measured using whole-body and ring dosimeters. Generators included those based on wet-chemical-process- and emanation-based technology. (3) Results: During generator handling, varying levels of ²²⁰Rn were observed in the vicinity of generators. An additional monthly whole-body dose must be considered when handling different sources of ²¹²Pb generators, and this depends upon local shielding and the handling approaches toward use of the technology. (4) Conclusions: ²²⁴Ra in any form (including radionuclide generators) should always be handled within a fume hood to keep potential contamination and exposure to personnel as low as reasonably achievable. Following standard practices of radiation safety, generators of ²¹²Pb can be used safely for theranostic applications. Full article

To address the performance degradation in model predictive control (MPC) under vehicle state uncertainties caused by external disturbances (e.g., crosswinds and tire cornering stiffness variations) and rigid constraint conflicts, we propose a robust MPC framework with adaptive weight adjustment and dynamic constraint relaxation. Traditional MPC methods often suffer from infeasibility or deteriorated tracking accuracies when handling model mismatches and disturbances. To overcome these limitations, three key innovations are introduced: a three-degree-of-freedom vehicle dynamic model integrated with recursive least squares-based online estimation of tire slip stiffness for real-time lateral force compensation; an adaptive weight adjustment mechanism that dynamically balances control energy consumption and tracking accuracy by tuning cost function weights based on real-time state errors; and a dynamic constraint relaxation strategy using slack variables with variable penalty terms to resolve infeasibility while suppressing excessive constraint violations. The proposed method is validated via ROS (noetic)–MATLAB2023 co-simulations under crosswind disturbances (0–3 m/s) and varying road conditions. The results show that the improved algorithm achieves a 13% faster response time (5.2 s vs. 6 s control cycles), a 15% higher minimum speed during cornering (2.98 m/s vs. 2.51 m/s), a 32% narrower lateral velocity fluctuation range ([−0.11, 0.22] m/s vs. [−0.19, 0.22] m/s), and reduced yaw rate oscillations ([−1.8, 2.8] rad/s vs. [−2.8, 2.5] rad/s) compared with a traditional fixed-weight MPC algorithm. These improvements lead to significant enhancements in trajectory tracking accuracy, dynamic response, and disturbance rejection, ensuring both safety and efficiency in autonomous vehicle control under complex uncertainties. The framework provides a practical solution for real-time applications in intelligent transportation systems. Full article

Rapid post-earthquake assessments of residential buildings are essential for preventing secondary disasters but typically require substantial human resources, with challenges related to accuracy and inspector safety. In wooden residential buildings, residual deformation can cause significant internal damage despite minor external indications. Thus, accurate evaluation of secondary components such as exterior walls and window frames is crucial. Although recent studies on digital assessment technologies focus mainly on reinforced concrete structures, limited research addresses wooden structures, especially considering residual deformation. This study proposes a rapid emergency risk assessment method utilizing 3D point cloud measurements obtained by a 3D scanning camera for densely built wooden residential areas. Its practicality was verified through three aspects. First, a comparison with conventional methods showed that the measurement accuracy of the proposed method is sufficient for practical use, with errors significantly lower than the inclination thresholds used in emergency risk assessments (e.g., 1/60 rad ≈ 1°). Second, in detection experiments using a deformed window frame model, the average error between the applied inclination and the measured values was less than 3%, demonstrating that deformation, dislodgement, and inclination of secondary components can be reliably detected from point cloud data. Third, field validation conducted in a commercial district confirmed that multiple buildings can be simultaneously measured and that individual buildings and their secondary components can be efficiently extracted and identified. Thus, this method demonstrates practical applicability and significantly improves the speed and efficiency of emergency assessments in densely built wooden residential areas. Full article

Late radiation-associated dysphagia (late-RAD) remains a challenge in head and neck cancer (HNC) survivorship, despite advancements in treatment methods. Although Fiberoptic Endoscopic Evaluation of Swallowing (FEES) stands as the preferred diagnostic approach for oropharyngeal dysphagia assessment in the HNC population, current studies lack a FEES-derived swallowing parameter characterization and phenotypic classification within this specific cohort. This study sought to employ FEES-based assessment to characterize swallowing safety and efficacy profiles, identify distinct phenotypes in HNC patients suffering from late-RAD, and examine potential correlations between safety and efficacy parameters. A retrospective analysis included twenty-four post-radiotherapy HNC patients evaluated using standardized FEES protocols across three bolus consistencies (liquid, semisolid, and solid). Swallowing safety was quantified using the Penetration–Aspiration Scale (PAS), while efficacy was measured via the Yale Pharyngeal Residue Severity Rating Scale (YPRSRS). Additionally, six distinct dysphagia phenotypes were characterized within the cohort. Propulsion deficit was the predominant phenotype (92%), followed by delayed pharyngeal phase (37.5%) and protective deficit (25%), with 46% of patients exhibiting multiple phenotypes. Unsafe swallowing occurred most frequently with liquid consistency (62.5%), while residue was most prevalent with semisolid (82.6% valleculae, 52.2% pyriform sinuses) and solid consistencies (92.3% valleculae, 53.8% pyriform sinuses). Significant correlations were found between penetration–aspiration and pharyngeal residue scores across consistencies (p < 0.05). FEES examination revealed distinct phenotypes in late radiation-associated dysphagia, with a predominance of propulsion deficit and significant interdependence between safety and efficacy parameters. Full article

Traffic congestion represents an urban challenge that authorities are trying to solve through various means. Current traffic management systems do not solve these challenges, which is why the research presents a new proposal for a traffic optimization system. The proposed solution integrates small-sized equipment (ESP32 equipped with accelerometers, gyroscopes, and cameras), cloud-based AI services (Azure Content Safety), and a multi-parametric analytical framework for real-time navigation. The system uses the Traffic Optimization Algorithm (TOA) proposed by the authors to calculate the Global Route Quality Indicator (GRQIk). It associates each route with a value based on which the degree of optimality is estimated. GRQIk is calculated based on the distance traveled, traffic delays, estimated travel time, road safety, and the individual’s sensitivity. Real-time data are collected using ESP32, with a pothole detection threshold set at 0.8 rad/s. Through the TomTom API, four alternative routes are identified. The performance evaluation showed that GRQIk differentiates route quality, with scores ranging from 26.40% for optimal routes to 100% for the least favorable ones. In addition, Azure’s Content Safety API achieved 100% accuracy in identifying violent incidents and accidents. The limitations of the research concern the small number of images available to test the Content Safety service. The research establishes new approaches for future developments in the field of smart transportation. Full article

Multi-temporal synthetic aperture radar interferometry (MT-InSAR) has evolved from a niche research technique into a powerful global monitoring tool. With the launch of nationwide and continent-wide ground motion services (GMSs), freely available deformation data can now be analyzed on a large scale. However, their applicability for monitoring critical infrastructure, such as dams, has not yet been thoroughly assessed, and several challenges have hindered the integration of MT-InSAR into existing monitoring frameworks. These challenges include technical limitations, difficulties in interpreting deformation results, and the rigidity of existing safety protocols, which often restrict the adoption of remote sensing techniques for operational dam monitoring. This study evaluates the effectiveness of persistent scatterer (PS) data from the German ground motion service (Bodenbewegungsdienst Deutschland, BBD) in complementing time-consuming in situ techniques. By analyzing a gravity dam in Germany, BBD time series were compared with in situ pendulum data. We propose a two-stage assessment procedure: First, we evaluate the dam’s suitability for PS analysis using the CR-Index to identify areas with good radar visibility. Second, we assess the interpretability of BBD data for radial deformations by introducing a novel index that quantifies the radial sensitivity of individual PS points on the dam. This index is universally applicable and can be transferred to other types of infrastructure. The results revealed a fair correlation between PS deformations and pendulum data for many PS points (up to $R^2$ = 0.7). A priori feasibility assessments are essential, as factors such as topography, land cover, and dam type influence the applicability of the PS technique. The dam’s orientation relative to the look direction of the sensor emerged as a key criterion for interpreting radial deformations. For angle differences (${\Delta }_{\mathrm{RAD}}$) of up to 20° between the true north radial angle of a PS point and the satellite’s look direction, the line-of-sight (LOS) sensitivity accounts for approximately 50 to 70% of the true radial deformation, depending on the satellite’s incidence angle. This criterion is best fulfilled by dams aligned in a north–south direction. For the dam investigated in this study, the LOS sensitivity to radial deformations was low due to its east–west orientation, resulting in significantly higher errors (6 mm $\le RMSE\le 43$ mm) compared to in situ pendulum data. Eliminating PS points with an unfavorable alignment with the sensor should be considered before interpreting radial deformations. For implementation into operational monitoring programs, greater effort must be spent on near-real-time updates of BBD datasets. Full article

Background/Objectives: The objective of this study was to evaluate the oncological outcomes and safety of nerve-sparing (NS) robot-assisted radical prostatectomy (RARP) when applied without Prostate Imaging-Reporting and Data System (PI-RADS) ≥3 lesions or Gleason pattern ≥4 on biopsy in the peripheral zone (PZ). Methods: We retrospectively analyzed 208 patients who underwent RARP between August 2017 and December 2022, excluding those who had received preoperative hormonal therapy. After NS status stratification and patient characteristic adjustment using propensity score matching (PSM), positive resection margin (RM) rates and prostate-specific antigen (PSA) recurrence-free survival were compared. Urinary and sexual quality of life (QOL) were assessed using the Expanded Prostate Cancer Index Composite, along with predictive factors associated with positive RM and RM locations in the NS group. Results: NS was performed in 68.6% (n = 129) patients. After PSM, there were no significant differences in RM positivity (p = 0.811) or PSA recurrence-free survival (Log-rank p = 0.79), regardless of NS status. There was no difference in sexual function between groups, but urinary QOL was significantly better in the NS group from the third month onward. In the NS group, RM positivity was 27.9% (n = 36), and diagnostic PSA (odds ratio [OR], 1.110, p = 0.038) and clinical T stage (OR, 1.400, p = 0.038) were predictive factors. The RM positivity rate on the NS side was 10.8%. Conclusions: NS, based on the absence of PI-RADS ≥3 lesions or Gleason pattern ≥4 in PZ, did not increase RM positivity rate and increased early urinary QOL. Full article

Background: Cancer remains one of the leading causes of mortality worldwide, with radiotherapy playing a crucial role in its treatment. Intensity-modulated radiotherapy (IMRT) enables precise dose delivery to tumors while sparing healthy tissues. However, geometric uncertainties such as patient positioning errors and anatomical deformations can compromise treatment accuracy. Traditional methods use safety margins, which may lead to excessive irradiation of healthy organs or insufficient tumor coverage. Robust optimization techniques, such as minimax approaches, attempt to address these uncertainties but can result in overly conservative treatment plans. This study introduces an interval analysis-based optimization model for IMRT, offering a more flexible approach to uncertainty management. Methods: The proposed model represents geometric uncertainties using interval dose influence matrices and incorporates Bertoluzza’s metric to balance tumor coverage and organ-at-risk (OAR) protection. The $\theta$ parameter allows controlled robustness modulation. The model was implemented in matRad, an open-source treatment planning system, and evaluated on five prostate cancer cases. Results were compared against traditional Planning Target Volume (PTV) and minimax robust optimization approaches. Results: The interval-based model improved tumor coverage by 5.8% while reducing bladder dose by 4.2% compared to PTV. In contrast, minimax robust optimization improved tumor coverage by 25.8% but increased bladder dose by 23.2%. The interval-based approach provided a better balance between tumor coverage and OAR protection, demonstrating its potential to enhance treatment effectiveness without excessive conservatism. Conclusions: This study presents a novel framework for IMRT planning that improves uncertainty management through interval analysis. By allowing adjustable robustness modulation, the proposed model enables more personalized and clinically adaptable treatment plans. These findings highlight the potential of interval analysis as a powerful tool for optimizing radiotherapy outcomes, balancing treatment efficacy and patient safety. Full article

Background: The relationship between case volume and clinical outcomes is well established for most urological procedures but remains underexplored in prostate ultrasound/MRI fusion biopsy (UMFB). UMFB aims to detect clinically significant prostate cancer (csPCa) by adhering to cancer detection benchmarks for PI-RADS lesions identified via multiparametric MRI (mpMRI). These benchmarks, defined by Ahmed et al., include cumulative cancer detection rate (C-CDR) targets of >80% for PI-RADS 5, >50% for PI-RADS 4, and <20% for PI-RADS 1–3. Methods: This retrospective, single-center study analyzed the case volumes required for two experienced urologists (U1 and U2, each with >15 years of practice) to consistently achieve the Ahmed-defined C-CDR benchmarks for csPCa (ISUP grade ≥ 2) using UMFB. Both transrectal and transperineal approaches were included to enable comprehensive learning curve analysis. Data from 2017 to 2023 were reviewed, encompassing 157 UMFBs performed by U1 and 242 by U2, with a transrectal-to-perineal ratio of 7:3. Results: Both urologists achieved Ahmed-defined C-CDR targets from the outset. Over a median follow-up of 30 months, patients with initial PI-RADS 4 or 5 ratings and negative primary biopsies remained prostate cancer-free in 77% of cases for U1 and 91.2% for U2 (p = 0.152). Conclusions: This study demonstrates that experienced urologists can achieve high diagnostic accuracy and maintain patient safety immediately upon implementing UMFB, meeting established benchmarks without requiring additional procedural learning. Full article

In advanced driver-assistance systems (ADASs), the misalignment of the mounting angle of the automotive radar significantly affects the accuracy of object detection and tracking, impacting system safety and performance. This paper introduces the Automotive Radar Alignment Detection Network (AutoRAD-Net), a novel model that leverages complex-valued convolutional neural network (CV-CNN) to address azimuth misalignment challenges in automotive radars. By utilizing complex-valued inputs, AutoRAD-Net effectively learns the physical properties of the radar data, enabling precise azimuth alignment. The model was trained and validated using mounting angle offsets ranging from −3° to +3° and exhibited errors no greater than 0.15° across all tested offsets. Moreover, it demonstrated reliable predictions even for unseen offsets, such as −1.7°, showcasing its generalization capability. The predicted offsets can then be used for physical radar alignment or integrated into compensation algorithms to enhance data interpretation accuracy in ADAS applications. This paper presents AutoRAD-Net as a practical solution for azimuth alignment, advancing radar reliability and performance in autonomous driving systems. Full article

Detection of anomalies in video surveillance plays a key role in ensuring the safety and security of public spaces. The number of surveillance cameras is growing, making it harder to monitor them manually. So, automated systems are needed. This change increases the demand for automated systems that detect abnormal events or anomalies, such as road accidents, fighting, snatching, car fires, and explosions in real-time. These systems improve detection accuracy, minimize human error, and make security operations more efficient. In this study, we proposed the Composite Recurrent Bi-Attention (CRBA) model for detecting anomalies in surveillance videos. The CRBA model combines DenseNet201 for robust spatial feature extraction with BiLSTM networks that capture temporal dependencies across video frames. A multi-attention mechanism was also incorporated to direct the model’s focus to critical spatiotemporal regions. This improves the system’s ability to distinguish between normal and abnormal behaviors. By integrating these methodologies, the CRBA model improves the detection and classification of anomalies in surveillance videos, effectively addressing both spatial and temporal challenges. Experimental assessments demonstrate that the CRBA model achieves high accuracy on both the University of Central Florida (UCF) and the newly developed Road Anomaly Dataset (RAD). This model enhances detection accuracy while also improving resource efficiency and minimizing response times in critical situations. These advantages make it an invaluable tool for public safety and security operations, where rapid and accurate responses are needed for maintaining safety. Full article

A CFD (computational fluid dynamics) analysis to investigate the effects of the installation of a barrier in a hydrogen refueling station (HRS) mock-up facility, with a dummy vehicle and dispensers in the vapor cloud region, during a hydrogen-air explosion using a gas mixture volume of 70.16 m³ was conducted to determine whether the radXiFoam v2.0 code with the established analysis methodology to predict the peak overpressure can be utilized to evaluate the safety of a HRS with such a barrier installed in a large city in the Republic of Korea. The radXiFoam v2.0 code was developed on the basis of the XiFoam solver in the open-source CFD software OpenFOAM-v2112 by modifying C++ source codes in several libraries and governing equations so as to ensure effective calculations of the hydrogen-air chemical reaction and radiative heat transfer through water vapor in a humid air environment and to remove unnecessary warning messages that arise when using the radXiFoam v1.0 code. First, we conducted a validation analysis on the basis of measured overpressure datasets from a near field to a far field of a vapor cloud explosion (VCE) site in the HRS mock-up facility to evaluate the uncertainty in prediction datasets by radXiFoam v2.0. After this validation analysis, we undertook CFD sensitivity calculations by installing barriers with heights of 2.1 m and 4.2 m at a horizontal distance of 2.3 m from the VCE region in the grid model used for the validation analysis to assess the effects of these barriers on reducing the peak overpressure of the blast wave. From these calculations, we judged that the radXiFoam v2.0 code can accurately simulate the effects of the barrier during a VCE, as the calculated overpressure reduction values according to the barrier height are reasonable on the basis of previous validation results from Stanford Research Institute’s explosion test with such a barrier. The results herein imply that the radXiFoam v2.0 code is feasible for use in HRS safety when barrier installation must meet the technical regulations of the Korea Gas Safety Corporation in a large city. Full article

This paper discusses the iteration of a seismic retrofit solution for shear-deficient end regions of 19 reinforced concrete (RC) moment-resisting frame (MRF) T-beams located in a 12-story RC MRF building in downtown Los Angeles, California. Local strengthening with externally bonded (EB) fiber-reinforced polymer (FRP) fabric was chosen as the preferred retrofit strategy due to its cost-effectiveness and proven performance. The FRP-shear-strengthening scheme for the deficient end-hinging regions of the MRF beams was designed and evaluated through large-scale cyclic testing of three replica specimens. The specimens were constructed at 4/5 scale and cantilever T-beam configurations with lengths of 3.40 m or 3.17 m. The cross-sectional geometry was 0.98 × 0.61 m with a top slab of 1.59 m in width and 0.12 m in thickness. Applied to these specimens were three different retrofit configurations, tested sequentially, namely: (a) unanchored continuous U-wrap; (b) anchored continuous U-wrap with conventional FRP-embedded anchors at the ends; and (c) fully closed external FRP hoops made of discrete FRP U-wrap strips and FRP through-anchors that penetrate the top slab and connect both ends of the FRP strips, combined with intermediate crack-control joints. The strengthening concept with FRP hoops precluded the premature debonding and anchor pullout issues of the two more conventional retrofit solutions and, despite a more challenging and labor-intensive installation, was selected for the in-situ implementation. The proposed hooplike EB-FRP shear-strengthening scheme enabled the deficient MRF beams to overcome a 30% shear overstress at the end-yielding region and to develop high-end rotations (e.g., 0.034 rad [3.4% drift] at peak and 0.038 rad [3.8% drift]) at strength loss for a beam that, otherwise, would have prematurely failed in shear. These values are about 30% larger than the ASCE 41 prescriptive value for the Life Safety (LS) performance objective. Energy dissipation achieved with the fully closed scheme was 108% higher than that of the unanchored FRP U-wrap and 45% higher than that of the FRP U-wrap with traditional embedded anchors. The intermediate saw-cut grooves successfully attracted crack formation between the strips and away from the FRP reinforcement, which contributed to not having any discernable debonding of the strips up to 3% drift. This paper presents the experimental evaluation of the three large-scale laboratory specimens that were used as the design basis for the final retrofit solution. Full article

Genotoxic substances widely exist in the environment and the food supply, posing serious health risks due to their potential to induce DNA damage and cancer. Traditional genotoxicity assays, while valuable, are limited by insufficient sensitivity, specificity, and efficiency, particularly when applied to complex food matrices. This study introduces a multiparametric high-content analysis (HCA) for the detection of genotoxic substances in complex food matrices. The developed assay measures three genotoxic biomarkers, including γ-H2AX, p-H3, and RAD51, which enhances the sensitivity and accuracy of genotoxicity screening. Moreover, the assay effectively distinguishes genotoxic compounds with different modes of action, which not only offers a more comprehensive assessment of DNA damage and the cellular response to genotoxic stress but also provides new insights into the exploration of genotoxicity mechanisms. Notably, the five tested food matrices, including coffee, tea, pak choi, spinach, and tomato, were found not to interfere with the detection of these biomarkers under proper dilution ratios, validating the robustness and reliability of the assay for the screening of genotoxic compounds in the food industry. The integration of multiple biomarkers with HCA provides an efficient method for detecting and assessing genotoxic substances in the food supply, with potential applications in toxicology research and food safety. Full article

Induction motors (IMs) must meet high reliability and safety standards in mission-critical applications, such as electric vehicles (EVs), where sensorless control strategies are fundamental. However, sensorless rotor speed estimation demands improvements to overcome filtering distortions, tuning complexities, and sensitivity to IM model mismatch. Algebraic methods offer inherent filtering capabilities and design flexibility to address these challenges without introducing additional dynamics into the control system. The objective of this paper is to provide an algebraic estimation strategy that yields an accurate rotor speed estimate for sensorless IM control. The strategy includes an algebraic estimator with single-parameter tuning and inherent filtering action. We propose an EV case study to experimentally evaluate and compare its performance with a typical drive cycle and a dynamic torque load that emulates a small-scale EV power train. The algebraic estimator exhibited a signal-to-noise ratio (SNR) of 43 dB. The closed-loop experiment for the EV case study showed average tracking errors below 1 rad/s and similar performance compared to a well-known sensorless strategy. Our results show that the proposed algebraic estimation strategy works effectively in a nominal speed range for a practical IM sensorless application. The algebraic estimator only requires single-parameter tuning and potentially facilitates IM model updates using a resetting scheme. Full article