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17 pages, 3305 KB  
Article
Assessing the Diagnostic Validity of Torsobarography in Scoliosis
by Nico Stecher, Lea Richter, Arkadiusz Łukasz Żurawski, Andreas Heinke, Maximilian Robert Harder, Thurid Jochim, Paula Schumann, Wojciech Piotr Kiebzak and Hagen Malberg
Sensors 2025, 25(8), 2485; https://doi.org/10.3390/s25082485 - 15 Apr 2025
Cited by 1 | Viewed by 1599
Abstract
Adolescent idiopathic scoliosis (AIS) is treated with various forms of conservative care or surgery, depending on the degree of severity. When AIS is detected early, it can be monitored and initially treated with reduced invasiveness to prevent further progression. AIS manifests itself through [...] Read more.
Adolescent idiopathic scoliosis (AIS) is treated with various forms of conservative care or surgery, depending on the degree of severity. When AIS is detected early, it can be monitored and initially treated with reduced invasiveness to prevent further progression. AIS manifests itself through deformations of the trunk, which are mostly identified as asymmetries in manual clinical examination. Torsobarography is a new pressure-based surface topographic system for posture analysis and evaluates such associated morphologic asymmetries. The aim of this study is to investigate the diagnostic validity of torsobarography by examining correlation of extracted torsobarographic indices with the Cobb angle and its ability to differentiate between different severities of scoliosis: no scoliosis, mild scoliosis, and moderate scoliosis. A total of 87 subjects (51 females and 36 males) were examined with torsobarography. Six torsobarographic indices were calculated for all subjects: torsobarography angle (TBA), sagittal imbalance index (SII), torso asymmetry index (TAI), shoulder asymmetry angle (SAA), waist asymmetry angle (WAA), and pelvis asymmetry Angle (PAA). These indices were correlated with the Cobb angle, and the differences between severities were statistically analyzed. Three out of six indices (TBA, TAI, and WAA) were able to significantly distinguish between mild and moderate scoliosis. Additionally, those indices showed moderate correlation (ρ = 0.37–0.50) with the Cobb angle measurements. The WAA was the only statistically significant index capable of differentiating between no scoliosis and moderate scoliosis. This study is the first to demonstrate that torsobarography can distinguish between different severities of scoliosis and thus identify a scoliotic deformity that requires bracing over monitoring. Full article
(This article belongs to the Special Issue Intelligent Medical Sensors and Applications)
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17 pages, 4564 KB  
Article
Vertical Movement of Head, Withers, and Pelvis of High-Level Dressage Horses Trotting in Hand vs. Being Ridden
by Hilary M. Clayton, Sarah Jane Hobbs, Marie Rhodin, Elin Hernlund, Mick Peterson, Rosalie Bos and Filipe Serra Bragança
Animals 2025, 15(2), 241; https://doi.org/10.3390/ani15020241 - 16 Jan 2025
Cited by 3 | Viewed by 2155
Abstract
Prior to international competitions, dressage horses are evaluated for fitness to compete while trotting in hand on a firm surface. This study compares the kinematics of experienced dressage horses trotting under fitness-to-compete conditions vs. performing collected and extended trot when ridden on a [...] Read more.
Prior to international competitions, dressage horses are evaluated for fitness to compete while trotting in hand on a firm surface. This study compares the kinematics of experienced dressage horses trotting under fitness-to-compete conditions vs. performing collected and extended trot when ridden on a sand-fiber arena surface. The hypotheses are that the vertical range of motion (ROM) and left–right asymmetries in minimal and maximal heights of axial body segments at ridden trot exceed those when trotting in hand. Inertial measurement units (IMUs) attached mid-dorsally to the head, withers, and pelvis of 19 actively competing dressage horses measured the vertical ROM and left–right asymmetries in minimal (MinDiff) and maximal (MaxDiff) heights of the midline sensors. The vertical ROM was greater for both types of ridden trot, reflecting greater impulsion in response to the riders’ aids. Head MinDiff/MaxDiff and withers MaxDiff were significantly higher under both ridden conditions. Pelvis MinDiff was significantly the largest for collected trot. Compared with trot in hand, left–right differences in limb protraction were larger for extended and collected trot in the forelimbs but only for extended trot in the hind limbs. The rider’s influence increases the horse’s impulsion and vertical ROM, which may exacerbate inherent asymmetries in muscular strength when lowering the haunches and elevating the withers. Full article
(This article belongs to the Special Issue Equine Gait Analysis: Translating Science into Practice)
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9 pages, 2256 KB  
Communication
Progressive and Asymmetrical Deadlift Loads Captured by Wearable Motion Tape Sensors
by Elijah Wyckoff, David Sten, Regan Wareham and Kenneth J. Loh
Sensors 2024, 24(23), 7700; https://doi.org/10.3390/s24237700 - 2 Dec 2024
Cited by 3 | Viewed by 2609
Abstract
Weight training is widely adopted and highly effective for enhancing both muscular strength and endurance. A popular weightlifting exercise is the deadlift, which targets multiple muscle groups including the lower back, glutes, and hamstrings. However, incorrect technique (i.e., poor form) can slow training [...] Read more.
Weight training is widely adopted and highly effective for enhancing both muscular strength and endurance. A popular weightlifting exercise is the deadlift, which targets multiple muscle groups including the lower back, glutes, and hamstrings. However, incorrect technique (i.e., poor form) can slow training progress, result in asymmetrical muscle development, and cause serious injuries. The objective of this study was to validate that a self-adhesive, elastic fabric, wearable, skin-strain sensor called Motion Tape (MT) could monitor a person’s posture while performing deadlift exercises. Two pairs of Motion Tape were attached on the front and back sides of the pelvis at each posterior superior iliac spine to record muscle engagement during deadlift exercises. The results of this preliminary study confirmed that the MT identified asymmetry in muscle engagement during deadlifting repetitions. In addition, the sensors could quantify the different levels of effort exerted according to the deadlift weight load. Full article
(This article belongs to the Special Issue Wearable Sensors for Optimising Rehabilitation and Sport Training)
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15 pages, 2734 KB  
Review
Comprehensive Analysis of Pelvic Asymmetries in Low Back Pain, Scoliosis, Post-Traumatic Pelvic Dysfunctions and Obstetric Changes: A Narrative Review Focused on Clinical Relevance
by Inés Cruz-Medel, Daiana Priscila Rodrigues-de-Souza and Francisco Alburquerque-Sendín
Symmetry 2024, 16(10), 1304; https://doi.org/10.3390/sym16101304 - 3 Oct 2024
Cited by 4 | Viewed by 9583
Abstract
The human pelvis is a complex structure, which participates in the biomechanical functioning of the musculoskeletal system. Although it is considered a symmetrical entity, the morphology of the pelvis is subject to different factors that alter its anatomy, function or biomechanics, such as [...] Read more.
The human pelvis is a complex structure, which participates in the biomechanical functioning of the musculoskeletal system. Although it is considered a symmetrical entity, the morphology of the pelvis is subject to different factors that alter its anatomy, function or biomechanics, such as age, bipedal locomotion, obstetric changes and sexual dimorphism. However, how these factors influence pelvic asymmetry is unknown. Some evidence suggests that this condition leads to different pathological states, such as chronic low back pain, scoliosis, post-traumatic pelvic dysfunctions and obstetric changes. Therefore, pelvic asymmetries present a significant challenge in clinical practice due to their multifactorial nature and their potential impact on quality of life. Multidisciplinary research and collaboration are essential to improve understanding and develop more effective and specific identification and treatment approaches in the presence of pelvic asymmetries. Full article
(This article belongs to the Special Issue Symmetry/Asymmetry in Life Sciences: Feature Papers 2024)
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9 pages, 6405 KB  
Article
Anterior Sacroiliac Fracture Dislocation: A Comparative Radiologic analysis of Crescent Fractures in Pelvic Ring Injuries: A Retrospective Study
by You-Seung Chun, Kyeong-Eon Kwon and Se-Won Lee
Medicina 2024, 60(8), 1375; https://doi.org/10.3390/medicina60081375 - 22 Aug 2024
Cited by 1 | Viewed by 2365
Abstract
Background and Objectives: Anterior sacroiliac fracture dislocation (ASFD), also known as locked pelvis, is a rarely reported diagnosis. The types of ASFDs are often misdiagnosed as lateral compression fractures due to the presence of crescent fractures. In this study, we distinguished ASFD from [...] Read more.
Background and Objectives: Anterior sacroiliac fracture dislocation (ASFD), also known as locked pelvis, is a rarely reported diagnosis. The types of ASFDs are often misdiagnosed as lateral compression fractures due to the presence of crescent fractures. In this study, we distinguished ASFD from lateral compression fractures (LC 2) and studied their characteristics. Materials and Methods: This is a retrospective study involving patients from a Level 1 trauma center. Fifty-nine patients under the age of 65 years with crescent fractures caused by a high-energy mechanism were investigated. Results: The incidence of ASFD was 25% (15 of 59) in patients with crescent fractures. Among the 15 patients, 6 had override of the ilium over the sacrum, inhibiting reduction in the sacroiliac joint. Pre-operative radiographic evaluations revealed that vertical displacement of the ASFD was larger than that of lateral compression fracture (LC 2) in the outlet view (mean 9.5 vs. 1.9 mm, p = 0.013), and the pelvic asymmetry ratio was larger in ASFD (mean 7.8 vs. 4.1, p = 0.006) in the pelvis AP view. All patients achieved union after surgery. Post-operative radiography showed no significant vertical displacement difference. There was no difference in vascular injury or hemodynamic instability requiring embolization or preperitoneal pelvic packing (PPP) between the two groups. Conclusions: Patients with ASFD have greater vertical displacement and asymmetry compared to patients with LC 2 fractures. These fractures must be distinguished for appropriate reduction and anterior plate fixation. Full article
(This article belongs to the Special Issue Clinical Care and Updates on Hip Fractures)
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13 pages, 844 KB  
Article
Associations between Racing Thoroughbred Movement Asymmetries and Racing and Training Direction
by Bronte Forbes, Winnie Ho, Rebecca S. V. Parkes, Maria Fernanda Sepulveda Caviedes, Thilo Pfau and Daniel R. Martel
Animals 2024, 14(7), 1086; https://doi.org/10.3390/ani14071086 - 3 Apr 2024
Cited by 8 | Viewed by 2096
Abstract
Background: Racehorses commonly train and race in one direction, which may result in gait asymmetries. This study quantified gait symmetry in two cohorts of Thoroughbreds differing in their predominant exercising direction; we hypothesized that there would be significant differences in the direction of [...] Read more.
Background: Racehorses commonly train and race in one direction, which may result in gait asymmetries. This study quantified gait symmetry in two cohorts of Thoroughbreds differing in their predominant exercising direction; we hypothesized that there would be significant differences in the direction of asymmetry between cohorts. Methods: 307 Thoroughbreds (156 from Singapore Turf Club (STC)—anticlockwise; 151 from Hong Kong Jockey Club (HKJC)—clockwise) were assessed during a straight-line, in-hand trot on firm ground with inertial sensors on their head and pelvis quantifying differences between the minima, maxima, upward movement amplitudes (MinDiff, MaxDiff, UpDiff), and hip hike (HHD). The presence of asymmetry (≥5 mm) was assessed for each variable. Chi-Squared tests identified differences in the number of horses with left/right-sided movement asymmetry between cohorts and mixed model analyses evaluated differences in the movement symmetry values. Results: HKJC had significantly more left forelimb asymmetrical horses (Head: MinDiff p < 0.0001, MaxDiff p < 0.03, UpDiff p < 0.01) than STC. Pelvis MinDiff (p = 0.010) and UpDiff (p = 0.021), and head MinDiff (p = 0.006) and UpDiff (p = 0.017) values were significantly different between cohorts; HKJC mean values indicated left fore- and hindlimb asymmetry, and STC mean values indicated right fore- and hindlimb asymmetry. Conclusion: the asymmetry differences between cohorts suggest that horses may adapt their gait to their racing direction, with kinematics reflecting reduced ‘outside’ fore- and hindlimb loading. Full article
(This article belongs to the Section Equids)
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17 pages, 4286 KB  
Article
Objective Assessment of Equine Locomotor Symmetry Using an Inertial Sensor System and Artificial Intelligence: A Comparative Study
by Natalie Calle-González, Chiara Maria Lo Feudo, Francesco Ferrucci, Francisco Requena, Luca Stucchi and Ana Muñoz
Animals 2024, 14(6), 921; https://doi.org/10.3390/ani14060921 - 16 Mar 2024
Cited by 8 | Viewed by 4327
Abstract
In horses, quantitative assessment of gait parameters, as with the use of inertial measurement units (IMUs) systems, might help in the decision-making process. However, it requires financial investment, is time-consuming, and lacks accuracy if displaced. An innovative artificial intelligence marker-less motion tracking system [...] Read more.
In horses, quantitative assessment of gait parameters, as with the use of inertial measurement units (IMUs) systems, might help in the decision-making process. However, it requires financial investment, is time-consuming, and lacks accuracy if displaced. An innovative artificial intelligence marker-less motion tracking system (AI-MTS) may overcome these limitations in the field. Our aim was to compare the level of agreement and accuracy between both systems and visual clinical assessment. Twenty horses underwent locomotion analysis by visual assessment, IMUs, and AI-MTS systems, under the following conditions: straight hard (SH), straight soft (SS), left and right circle hard (LCH, RCH), and soft (LCS, RCS). A greater number of horses were considered sound by clinical examination, compared to those identified as symmetric by the two gait analysis systems. More limbs were considered asymmetric by the AI-MTS compared to IMUs, suggesting its greater sensitivity. The greatest agreement between the two systems was found for the difference between two minima in vertical head position in SH, while the lowest for the difference between two minima in vertical pelvis position in SS, reflecting the difficulties in assessing asymmetry of the hindlimbs. It is unknown what degree of asymmetry is clinically relevant, suggesting that more consistent use in training horses may help determine the thresholds for asymmetry. Some degree of asymmetry may be clinically relevant, suggesting its regular use in training horses. Full article
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14 pages, 836 KB  
Article
The Effectiveness of Early Rehabilitation in Limiting the Progression of Idiopathic Scoliosis
by Marek Kluszczyński, Katarzyna Zaborowska-Sapeta, Ireneusz Kowalski and Ilona Karpiel
J. Clin. Med. 2024, 13(5), 1422; https://doi.org/10.3390/jcm13051422 - 29 Feb 2024
Cited by 3 | Viewed by 3267
Abstract
Background: The purpose of this study was to assess specific rehabilitation methods’ effectiveness in early idiopathic scoliosis (IS) development, focusing on lower limb functional inequality’s role in scoliosis progression. Materials and Methods: This study comprised 812 patients aged 6–16 years at risk [...] Read more.
Background: The purpose of this study was to assess specific rehabilitation methods’ effectiveness in early idiopathic scoliosis (IS) development, focusing on lower limb functional inequality’s role in scoliosis progression. Materials and Methods: This study comprised 812 patients aged 6–16 years at risk of developing idiopathic scoliosis (IS). The mean (SD) age was 10.66 (3.16) years. Patients were categorized into high- and medium-risk groups based on the angle of trunk rotation (ATR) size. Specific scoliosis physiotherapy was used, and the average follow-up period was 28.1 ± 14.5 months. Changes in ATR, Cobb angle, and functional length of the lower limbs pre- and post-treatment were statistically analyzed across three age groups (6–9, 10–12, and 13–16 years) and three scoliosis locations. Results: Significant effectiveness of early rehabilitation was observed in the high-risk group of children aged 6–9 years. In the medium-risk group, significant reductions in ATR were observed in both the 6–9 and 10–12 age groups across all three scoliosis locations. Additionally, there was a significant decrease in the Cobb angle in the thoracolumbar region and a significant reduction in lower limb inequality across all age groups and scoliosis locations. Conclusions: The early implementation of specific physiotherapy may enhance the efficacy of idiopathic scoliosis treatment by attenuating factors contributing to its progression. Full article
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12 pages, 3104 KB  
Article
Seat Pressure Asymmetries after Cycling at Constant Intensity
by Laura Lepasalu, Jaan Ereline, Märt Reinvee and Mati Pääsuke
Symmetry 2024, 16(3), 270; https://doi.org/10.3390/sym16030270 - 24 Feb 2024
Viewed by 2031
Abstract
The aim of this study was to compare seat pressure asymmetries before and after 30 min cycling at constant intensity in association with pelvic anthropometric parameters and skeletal muscle fatigue. Twelve male road cyclists aged 18–30 years (mean training experience 9.9 ± 2.5 [...] Read more.
The aim of this study was to compare seat pressure asymmetries before and after 30 min cycling at constant intensity in association with pelvic anthropometric parameters and skeletal muscle fatigue. Twelve male road cyclists aged 18–30 years (mean training experience 9.9 ± 2.5 years) participated. Pelvic anthropometric data and body composition were measured with dual-energy X-ray absorptiometry. Participants performed 30 min cycling at 50% peak power output at constant intensity on a cyclus-2 ergometer. Muscle fatigue during cycling was assessed by surface electromyogram spectral mean power frequency (MPF) for the back, gluteal, and thigh muscles. The pressure mapping system was used to assess sitting symmetry before and after the cycling exercise. At the end of cycling, MPF was decreased (p < 0.05) in the dominant side’s erector spinae muscle and the contralateral gluteal muscle. After the exercise, a significant (p < 0.05) asymmetry in seat pressure was observed under the ischial tuberosity based on the peak pressure right to left ratio, whereas peak pressure decreased under the left ischial tuberosity. After the exercise, the relationship (p < 0.05) between pelvis width and pressure under the ischial tuberosity occurred on the dominant side of the body. In conclusion, an asymmetry was revealed after the constant-load cycling exercise by peak pressure ratio right to left side. Further studies should address the role of seat pressure asymmetries before and after cycling exercises at different intensities and durations. Full article
(This article belongs to the Special Issue Symmetry and Asymmetry in Sport Sciences)
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10 pages, 1074 KB  
Article
Rotation and Asymmetry of the Axial Plane Pelvis in Cerebral Palsy: A CT-Based Study
by Akbar N. Syed, Jenny L. Zheng, Christine Goodbody, Patrick J. Cahill, David A. Spiegel and Keith Baldwin
Children 2024, 11(1), 63; https://doi.org/10.3390/children11010063 - 2 Jan 2024
Cited by 1 | Viewed by 3543
Abstract
Spinopelvic malignment is commonly seen with non-ambulatory cerebral palsy (CP). Axial plane deformation is not well described in the literature. The purpose of this study was to describe and quantify the axial plane deformity in CP using CT scans and compare it to [...] Read more.
Spinopelvic malignment is commonly seen with non-ambulatory cerebral palsy (CP). Axial plane deformation is not well described in the literature. The purpose of this study was to describe and quantify the axial plane deformity in CP using CT scans and compare it to normal controls. We retrospectively collected data using CT scans of the abdomen and pelvis of 40 patients with GMFCS IV/V CP and neuromuscular scoliosis (CPP) and normal controls (NP) matched by age and sex. Pre-operative Cobb angle was recorded for the CP patients. Pelvic anatomy was evaluated at the supra-acetabular region of bone using two angles—iliac wing angle and sacral ala angle, measured for each hemipelvis. The larger of each hemipelvis angle was considered externally rotated while the smaller angle was considered internally rotated, termed as follows—iliac wing external (IWE) and internal (IWI); sacral ala external (SAE), and internal (SAI). Differences were noted using an independent t-test while correlations with Cobb angle were performed using Pearson’s correlation. Iliac wing measurements showed the externally rotated hemipelvis showed a significantly greater magnitude compared with normal controls at 47.3 ± 18.1 degrees vs. 26.4 ± 3.7 degrees in NP (p < 0.001) while no internal rotation was observed (p > 0.05). Sacral ala measurements showed greater magnitude in both external and internal rotation. SAE was 119.5 ± 9.5 degrees in CPP vs. 111.2 ± 7.7 degrees in NP (p < 0.001) while SAI was 114.1 ± 8.5 degrees in CPP vs. 107.9 ± 7.5 degrees in NP (p = 0.001). In the CP cohort, the mean Cobb angle was 61.54 degrees (n = 37/40). Cobb angle correlated with the degree of external iliac wing rotation—IWE (r = 0.457, p = 0.004) and degree of absolute difference in the rotation of the iliac wing (r = 0.506, p = 0.001). The pelvis in a patient with CP scoliosis is asymmetrically oriented exhibiting a greater external rotation of one hemipelvis relative to normal controls. The severity of neuromuscular scoliosis is related to the pelvic axial rotation in CP patients. Axial plane deformity exists in the CP pelvis and this deformity warrants consideration when considering spinopelvic instrumentation strategies and outcomes of supra-pelvic and infra-pelvic pathologies. Full article
(This article belongs to the Special Issue Research in Paediatric Orthopaedic Surgery)
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17 pages, 3924 KB  
Article
Overground Robotic Gait Trainer mTPAD Improves Gait Symmetry and Weight Bearing in Stroke Survivors
by Danielle Marie Stramel, Lauren Winterbottom, Joel Stein and Sunil K. Agrawal
Bioengineering 2023, 10(6), 698; https://doi.org/10.3390/bioengineering10060698 - 8 Jun 2023
Cited by 6 | Viewed by 3324
Abstract
Stroke is a leading cause of disability, impairing the ability to generate propulsive forces and causing significant lateral gait asymmetry. We aim to improve stroke survivors’ gaits by promoting weight-bearing during affected limb stance. External forces can encourage this; e.g., vertical forces can [...] Read more.
Stroke is a leading cause of disability, impairing the ability to generate propulsive forces and causing significant lateral gait asymmetry. We aim to improve stroke survivors’ gaits by promoting weight-bearing during affected limb stance. External forces can encourage this; e.g., vertical forces can augment the gravitational force requiring higher ground reaction forces, or lateral forces can shift the center of mass over the stance foot, altering the lateral placement of the center of pressure. With our novel design of a mobile Tethered Pelvic Assist Device (mTPAD) paired with the DeepSole system to predict the user’s gait cycle percentage, we demonstrate how to apply three-dimensional forces on the pelvis without lower limb constraints. This work is the first result in the literature that shows that with an applied lateral force during affected limb stance, the center of pressure trajectory’s lateral symmetry is significantly closer to a 0% symmetry (5.5%) than without external force applied (9.8%,p<0.05). Furthermore, the affected limb’s maximum relative pressure (p) significantly increases from 233.7p to 234.1p (p<0.05) with an applied downward force, increasing affected limb loading. This work highlights how the mTPAD increases weight-bearing and propulsive forces during gait, which is a crucial goal for stroke survivors. Full article
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14 pages, 15489 KB  
Article
Comparison of Traditional Physical Intervention Techniques vs. Operational Tactical Procedures and Techniques in the Use of Force during Police Arrests
by José C. Vera-Jiménez, Domingo Villero-Carro, Andrés Pastor-Fernandez, James Shippen, Marta Ferreiro-González, José C. Vera-Jurado, José A. Álvarez and Jesús Ayuso
Safety 2023, 9(2), 39; https://doi.org/10.3390/safety9020039 - 2 Jun 2023
Cited by 2 | Viewed by 4389
Abstract
(1) Background: A set of relevant police ergonomic parameters (PEP) have been used for the assessment and prevention of occupational risks involved in police physical interventions (PITs). Through this set of PEPs, a comparison has been made between two traditional PITs against two [...] Read more.
(1) Background: A set of relevant police ergonomic parameters (PEP) have been used for the assessment and prevention of occupational risks involved in police physical interventions (PITs). Through this set of PEPs, a comparison has been made between two traditional PITs against two novel OTPs (operational tactical procedures). (2) Method: The data have been collected by means of a motion capture suit fitted with 19 inertial measurement units (IMUs). A specific and powerful software package specific for ergonomic analysis has been used to manage the large amount of data registered and to generate a series of three-dimensional plots. Traditional PITs and newer OTPs have been performed for their analysis. Specifically, the PEPs corresponding to the implementation of four PITs have been analyzed by collecting the measurements provided by a set of IMUs installed on a motion capture suit, and their occupational risk assessments have been compared against those corresponding to newer OTPs. (3) Results: For the four PITs, the PEPs have been analyzed with the measured values from the IMUs, throughout the duration of each technique. The two traditional intervention techniques have scored higher than the new OTPs in the REBA system, the asymmetry angle, L5-pelvis shear and joint contact forces, and the total muscle power measurements. (4) Conclusions: It has been confirmed that the new OTPs minimize the risk of injuries, since their PEPs reached lower values than those corresponding to the traditional PITs, which are still being taught at police academies. Full article
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9 pages, 2554 KB  
Article
Can Imaging Using Radiomics and Fat Fraction Analysis Detect Early Tissue Changes on Historical CT Scans in the Regions of the Pancreas Gland That Subsequently Develop Adenocarcinoma?
by Ronald Lee Korn, Andre Burkett, Jeff Geschwind, Dominic Zygadlo, Taylor Brodie, Derek Cridebring, Daniel D. Von Hoff and Michael J. Demeure
Diagnostics 2023, 13(5), 941; https://doi.org/10.3390/diagnostics13050941 - 1 Mar 2023
Cited by 4 | Viewed by 12284
Abstract
Despite a growing number of effective therapeutic options for patients with pancreatic adenocarcinoma, the prognosis remains dismal mostly due to the late-stage presentation and spread of the cancer to other organs. Because a genomic analysis of pancreas tissue revealed that it may take [...] Read more.
Despite a growing number of effective therapeutic options for patients with pancreatic adenocarcinoma, the prognosis remains dismal mostly due to the late-stage presentation and spread of the cancer to other organs. Because a genomic analysis of pancreas tissue revealed that it may take years, if not decades, for pancreatic cancer to develop, we performed radiomics and fat fraction analysis on contrast-enhanced CT (CECT) scans of patients with historical scans showing no evidence of cancer but who subsequently went on to develop pancreas cancer years later, in an attempt to identify specific imaging features of the normal pancreas that may portend the subsequent development of the cancer. In this IRB-exempt, retrospective, single institution study, CECT chest, abdomen, and pelvis (CAP) scans of 22 patients who had evaluable historical imaging data were analyzed. The images from the “healthy” pancreas were obtained between 3.8 and 13.9 years before the diagnosis of pancreas cancer was established. Afterwards, the images were used to divide and draw seven regions of interest (ROIs) around the pancreas (uncinate, head, neck-genu, body (proximal, middle, and distal) and tail). Radiomic analysis on these pancreatic ROIs consisted of first order quantitative texture analysis features such as kurtosis, skewness, and fat quantification. Of all the variables tested, fat fraction in the pancreas tail (p = 0.029) and asymmetry of the histogram frequency curve (skewness) of pancreas tissue (p = 0.038) were identified as the most important imaging signatures for subsequent cancer development. Changes in the texture of the pancreas as measured on the CECT of patients who developed pancreas cancer years later could be identified, confirming the utility of radiomics-based imaging as a potential predictor of oncologic outcomes. Such findings may be potentially useful in the future to screen patients for pancreatic cancer, thereby helping detect pancreas cancer at an early stage and improving survival. Full article
(This article belongs to the Special Issue Advances and Novelties in Hepatobiliary and Pancreatic Imaging 2.0)
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10 pages, 1302 KB  
Article
The Variable Influence of Orthotic Management on Hip and Pelvic Rotation in Children with Unilateral Neurogenic Equinus Deformity
by Domenic Grisch, Manuela Stäuble, Sandra Baumgartner, Hubertus J. A. van Hedel, Andreas Meyer-Heim, Thomas Dreher and Britta Krautwurst
Children 2023, 10(2), 307; https://doi.org/10.3390/children10020307 - 6 Feb 2023
Viewed by 2449
Abstract
Background: Equinus deformity with or without concomitant drop foot is a common finding in children with unilateral spastic cerebral palsy and spastic hemiplegia of other causes. Hypothetically, these deformities may lead to pelvic retraction and hip internal rotation during gait. Orthoses are used [...] Read more.
Background: Equinus deformity with or without concomitant drop foot is a common finding in children with unilateral spastic cerebral palsy and spastic hemiplegia of other causes. Hypothetically, these deformities may lead to pelvic retraction and hip internal rotation during gait. Orthoses are used to reduce pes equinus during gait and to restore hindfoot first contact. Objective: We aimed to investigate whether the use of orthotic equinus correction reduces rotational hip and pelvic asymmetries. Methods: In a retrospective study, 34 children with unilateral spastic cerebral palsy or spastic hemiplegia of other causes underwent standardized instrumented 3D gait analysis with and without orthotic equinus management. We analyzed the differences in the torsional profile during barefoot walking and while wearing orthoses, as well as investigated the influence of ankle dorsiflexion and femoral anteversion on pelvic and hip kinematics and hip kinetics. Results: Wearing orthoses corrected pes equinus and pelvic internal rotation at the end of the stance phase and in the swing phase compared to barefoot walking. Hip rotation and the rotational moment did not significantly change with orthoses. Orthotic management or femoral anteversion did not correlate to pelvic and hip asymmetry. Conclusion: The findings indicate that the correction of the equinus by using orthoses had a variable effect on the asymmetry of the hip and pelvis and internal rotation; both appear to have a multifactorial cause that is not primarily driven by the equinus component. Full article
(This article belongs to the Special Issue Orthopedics and Trauma in Children)
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44 pages, 8202 KB  
Article
Is Markerless More or Less? Comparing a Smartphone Computer Vision Method for Equine Lameness Assessment to Multi-Camera Motion Capture
by Felix Järemo Lawin, Anna Byström, Christoffer Roepstorff, Marie Rhodin, Mattias Almlöf, Mudith Silva, Pia Haubro Andersen, Hedvig Kjellström and Elin Hernlund
Animals 2023, 13(3), 390; https://doi.org/10.3390/ani13030390 - 24 Jan 2023
Cited by 29 | Viewed by 9100
Abstract
Computer vision is a subcategory of artificial intelligence focused on extraction of information from images and video. It provides a compelling new means for objective orthopaedic gait assessment in horses using accessible hardware, such as a smartphone, for markerless motion analysis. This study [...] Read more.
Computer vision is a subcategory of artificial intelligence focused on extraction of information from images and video. It provides a compelling new means for objective orthopaedic gait assessment in horses using accessible hardware, such as a smartphone, for markerless motion analysis. This study aimed to explore the lameness assessment capacity of a smartphone single camera (SC) markerless computer vision application by comparing measurements of the vertical motion of the head and pelvis to an optical motion capture multi-camera (MC) system using skin attached reflective markers. Twenty-five horses were recorded with a smartphone (60 Hz) and a 13 camera MC-system (200 Hz) while trotting two times back and forth on a 30 m runway. The smartphone video was processed using artificial neural networks detecting the horse’s direction, action and motion of body segments. After filtering, the vertical displacement curves from the head and pelvis were synchronised between systems using cross-correlation. This rendered 655 and 404 matching stride segmented curves for the head and pelvis respectively. From the stride segmented vertical displacement signals, differences between the two minima (MinDiff) and the two maxima (MaxDiff) respectively per stride were compared between the systems. Trial mean difference between systems was 2.2 mm (range 0.0–8.7 mm) for head and 2.2 mm (range 0.0–6.5 mm) for pelvis. Within-trial standard deviations ranged between 3.1–28.1 mm for MC and between 3.6–26.2 mm for SC. The ease of use and good agreement with MC indicate that the SC application is a promising tool for detecting clinically relevant levels of asymmetry in horses, enabling frequent and convenient gait monitoring over time. Full article
(This article belongs to the Special Issue Equine Gait Analysis: Translating Science into Practice)
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