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19 pages, 304 KB  
Article
Occupational Stress, Coping Strategies, and Resilience Among Health and Social Care Professionals Working with Children and Families in Greece: A Cross-Sectional Study
by Dimitrios Mimarakis, Philippa Kolokotroni, Eleni Plevriti, Maria Moudatsou and Sofia Koukouli
Healthcare 2026, 14(14), 2184; https://doi.org/10.3390/healthcare14142184 - 20 Jul 2026
Viewed by 908
Abstract
Context: Child-focused healthcare professionals serve as primary providers of both physical and psychosocial care to pediatric patients and their families. Consequently, they are exposed to substantial occupational and emotional challenges in the course of their practice. Objectives: This study examined the levels and [...] Read more.
Context: Child-focused healthcare professionals serve as primary providers of both physical and psychosocial care to pediatric patients and their families. Consequently, they are exposed to substantial occupational and emotional challenges in the course of their practice. Objectives: This study examined the levels and multidimensional aspects of occupational stress, coping strategies, and resilience among healthcare professionals providing care to pediatric patients and their families in Greece. Methods: Socio-demographic characteristics, perceived occupational stress, coping strategies (WCQ), and resilience were assessed in a sample of 202 child-focused healthcare (physicians and nurses) and social care professionals (social workers, psychologists, and special education professionals) employed across a range of health and psychosocial services in Greece. Multiple linear regression analyses using the enter method were performed to examine the associations among resilience, occupational stress, and coping strategies while controlling for relevant demographic and occupational variables. Results: Social support was significantly associated with gender. Positive coping was associated with age, work experience, and the WCQ subscales Social Support, Daydreaming, and Avoidance. Avoidance coping was positively associated with profession and Daydreaming. Significant differences were also observed according to age, occupational stress, positive coping, social support, and resilience. Hierarchical multiple regression analysis demonstrated that, positive coping was independently and most strongly associated with resilience (p < 0.001), whereas work stress was independently and negatively associated with resilience (p = 0.001), with higher perceived stress corresponding to lower levels of resilience. Conclusions: The findings highlight the central role of positive coping in relation to resilience among child-focused healthcare professionals, while demonstrating the negative association between occupational stress and resilience. These results underscore the need for interventions that strengthen effective coping strategies, reduce work-related stress, and enhance resilience among healthcare professionals. They also identify important knowledge gaps and support the need for future research examining occupational stress, its long-term consequences, and the coping mechanisms and resilience among professionals working with children and families. Full article
(This article belongs to the Special Issue Psychosocial Aspects of Childhood and Adolescent Health)
21 pages, 905 KB  
Article
Barriers and Facilitators in the Implementation of a Syndromic Antibiogram for Pediatric Patients Hospitalized in Maputo, Mozambique: A Qualitative Study Using the Dynamic Adaptation Process (DAP) Framework
by Darlenne B. Kenga, Troy D. Moon, Mohsin Sidat, Valéria Chicamba, Andrea Ntanga Kenga, Yara Manjate, Dércio Nhanala, Inês C. Caetano, Ramígio Pololo, Olga Cambaco and Jahit Sacarlal
Antibiotics 2026, 15(2), 178; https://doi.org/10.3390/antibiotics15020178 - 6 Feb 2026
Viewed by 1306
Abstract
Introduction: The global rise in antimicrobial resistance poses a growing threat to public health, particularly in low- and middle-income countries where diagnostic capacity and surveillance systems remain limited. In these settings, optimizing empiric antibiotic prescribing is critical, and syndromic antibiograms offer a promising [...] Read more.
Introduction: The global rise in antimicrobial resistance poses a growing threat to public health, particularly in low- and middle-income countries where diagnostic capacity and surveillance systems remain limited. In these settings, optimizing empiric antibiotic prescribing is critical, and syndromic antibiograms offer a promising approach to support evidence-based decision-making. This study examines anticipated barriers and facilitators to the adoption of syndromic antibiograms from the perspectives of pediatric clinicians and laboratory professionals at Maputo Central Hospital in Mozambique. Methods: Guided by the Dynamic Adaptation Process (DAP) framework, this qualitative study used semi-structured interviews with eighteen healthcare professionals to explore empiric antibiotic prescribing practices, perceptions of syndromic antibiograms, and system-level barriers and facilitators. Data were analyzed thematically using deductive codes derived from the DAP framework alongside inductive codes generated from participants’ narratives. Results: Barriers were identified at individual, organizational, and systems levels. Individual barriers included limited awareness, reliance on traditional practices, and resistance to change. Organizational barriers included weak leadership support, insufficient training, poor communication between clinicians and laboratory staff, suboptimal sample collection, heavy workloads, and staff shortages. Systems-level barriers comprised shortages of laboratory supplies and medicines, delays in laboratory results, and weak monitoring mechanisms. Facilitators included health worker motivation for evidence-based practice, organizational collaboration, peer and team support, and the presence of influential champions. Systems-level enablers included functional laboratory services, supportive institutional environments, alignment with clinical guidelines, and recognition of clinical utility. Conclusions: Successful implementation of syndromic antibiograms in LMIC will require addressing systemic and organizational barriers while fostering professional motivation, collaboration, and institutional support. Sustainable integration will depend on coordinated strategies—including resource strengthening, continuous training, supportive leadership, and structured monitoring—that collectively strengthen antimicrobial stewardship and inform health policy. Full article
(This article belongs to the Section Antibiotics Use and Antimicrobial Stewardship)
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12 pages, 1340 KB  
Review
Training for Pediatric Sepsis—A Medical Education Perspective and Potential Role of Artificial Intelligence
by Spyridon Karageorgos, Owen Hibberd, Dennis Ren, Yasmin Hornsby, Damian Roland and Ioannis Koutroulis
Children 2025, 12(11), 1542; https://doi.org/10.3390/children12111542 - 14 Nov 2025
Cited by 2 | Viewed by 1272
Abstract
Pediatric sepsis is a major cause of morbidity and mortality worldwide, with outcomes dependent on timely recognition and rigorous management. As clinical management of pediatric sepsis depends on early recognition and initial therapeutic steps, targeted educational materials for healthcare workers in these early [...] Read more.
Pediatric sepsis is a major cause of morbidity and mortality worldwide, with outcomes dependent on timely recognition and rigorous management. As clinical management of pediatric sepsis depends on early recognition and initial therapeutic steps, targeted educational materials for healthcare workers in these early phases of care are warranted. Findings of this review highlight and compare the role of traditional educational methods (e.g., lectures) to alternative teaching methods (e.g., use of virtual reality) in educating healthcare workers about pediatric sepsis. Overall, there is a gradual shift from traditional, teacher-centered, transmissive teaching methods to more collaborative, reflective, and learner-centered approaches. These pedagogical approaches, despite some potential limitations, offer opportunities to use technological enhancements and Artificial Intelligence (AI) to enhance teaching and learning across various methods. Full article
(This article belongs to the Special Issue Diagnosis, Treatment and Outcomes of Pediatric Septic Shock)
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11 pages, 306 KB  
Article
Evaluation of Tuberculosis Preventive Treatment Uptake Among People Living with HIV in PEPFAR-Supported Facilities in Zimbabwe
by Collins Timire, Tawanda Mapuranga, Ronald T. Ncube, Talent Maphosa, Sithabiso Dube, Nqobile Mlilo, Cynthia Chiteve, Selma Dar Berger, Owen Mugurungi, Fungai Kavenga, Tsitsi Mutasa-Apollo, Manners Ncube, Clorata Gwanzura, Macarthur Charles, Riitta A. Dlodlo and Julia Ershova
Trop. Med. Infect. Dis. 2025, 10(10), 296; https://doi.org/10.3390/tropicalmed10100296 - 18 Oct 2025
Cited by 1 | Viewed by 1319
Abstract
Tuberculosis preventive treatment (TPT) reduces the incidence of tuberculosis (TB) among people living with HIV (PLHIV), but its coverage remains suboptimal in most settings. We conducted a cross-sectional study to describe TPT uptake among PLHIV and factors influencing TPT initiation. Healthcare workers (HCWs) [...] Read more.
Tuberculosis preventive treatment (TPT) reduces the incidence of tuberculosis (TB) among people living with HIV (PLHIV), but its coverage remains suboptimal in most settings. We conducted a cross-sectional study to describe TPT uptake among PLHIV and factors influencing TPT initiation. Healthcare workers (HCWs) in selected facilities were trained and supported to strengthen TPT management among PLHIV, including children living with HIV (CLHIV). Of 1309 enrolled PLHIV, 1268 (97%) were eligible for TPT; 1078 (85%) initiated TPT, including 663/776 (86%) among those currently on ART and 415/492 (84%) among clients newly on ART. The major reasons for not starting TPT included stock-outs of TPT medicines, TB disease, and refusal of TPT, mostly by CLHIV and adults currently on ART. Optimal and sustained uptake of TPT can be achieved through ensuring uninterrupted stocks of TPT medicines, including shorter regimens and pediatric formulations, addressing knowledge deficits among HCWs, and improving demand for TPT by educating PLHIV and caregivers of CLHIV about the benefits and risks of TPT formulations. Full article
(This article belongs to the Special Issue New Perspectives in Tuberculosis Prevention and Control)
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18 pages, 327 KB  
Article
Demographic and Job-Related Predictors of Work-Related Quality of Life Among Healthcare Workers: Evidence from Public Sector Hospitals in Greece
by Olympia Christofilea, Maria Tsaousi, Loukia Psaridi, Panayota Sourtzi, Vasiliki Papanikolaou and George Dounias
Healthcare 2025, 13(17), 2142; https://doi.org/10.3390/healthcare13172142 - 28 Aug 2025
Viewed by 1668
Abstract
Background: Work-Related Quality of Life (WRQoL) is an essential aspect of the sustainability of the healthcare workforce, intimately connected to employee well-being, job fulfillment, and the standard of patient care. This research sought to evaluate WRQoL among healthcare employees in Greek public hospitals, [...] Read more.
Background: Work-Related Quality of Life (WRQoL) is an essential aspect of the sustainability of the healthcare workforce, intimately connected to employee well-being, job fulfillment, and the standard of patient care. This research sought to evaluate WRQoL among healthcare employees in Greek public hospitals, concentrating on the influence of demographic and work-related factors in a healthcare system affected by prolonged economic and public health crises. Methods: A cross-sectional study was conducted with 1022 staff members from 23 hospitals in the 1st Health Region of Attica, utilizing the validated Work-Related Quality of Life Scale (WRQoL). Data were analyzed using non-parametric tests, including Chi-square and Linear-by-Linear Association analyses. Results: The findings showed that 44.3% of employees experienced low WRQoL, with the lowest ratings found among younger workers, those on temporary contracts, and individuals working in pediatric hospitals. Holding a leadership position, being over 40 years old, and having a permanent job were linked to notably greater well-being and job satisfaction. A significant portion of participants viewed the working conditions and autonomy as insufficient, particularly in demanding institutional environments. Conclusions: These results emphasize the necessity for focused policy measures to enhance working conditions, guarantee job stability, and reinforce organizational support structures. Tackling structural shortcomings in the healthcare system is crucial for protecting workforce stability and the standard of public health services. Full article
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28 pages, 3978 KB  
Article
Long COVID in Healthcare Workers from a Pediatric Hospital in Romania: A Cross-Sectional Study of Prevalence, Symptom Burden, and the Role of Vaccination and Reinfection
by Maria Valentina Popa, Irina Luciana Gurzu, Claudia Mariana Handra, Cristina Mandanach, Bogdan Gurzu, Dana Elena Mîndru, Mădălina Duceac (Covrig), Mădălina Irina Ciuhodaru and Letiția Doina Duceac
J. Clin. Med. 2025, 14(16), 5782; https://doi.org/10.3390/jcm14165782 - 15 Aug 2025
Cited by 1 | Viewed by 1753
Abstract
Background/Objectives: Long COVID, characterized by persistent symptoms following SARS-CoV-2 infection, poses a significant occupational health concern among healthcare workers (HCWs). This study aimed to evaluate the prevalence of long COVID, symptom patterns, work-related impact, and vaccination status among healthcare personnel in a [...] Read more.
Background/Objectives: Long COVID, characterized by persistent symptoms following SARS-CoV-2 infection, poses a significant occupational health concern among healthcare workers (HCWs). This study aimed to evaluate the prevalence of long COVID, symptom patterns, work-related impact, and vaccination status among healthcare personnel in a Romanian pediatric hospital. Methods: A cross-sectional study was conducted in 2024 among 903 hospital employees during routine occupational health assessments. Data were collected using structured questionnaires and medical records, focusing on previous SARS-CoV-2 infection, vaccination status, persistent symptoms, and functional impact. Results: Long COVID was identified in 28.6% of participants, with excessive fatigue (53.5%), musculoskeletal pain, respiratory difficulties, and cognitive complaints being the most common symptoms. Staff with chronic comorbidities or increased exposure risk had significantly higher rates of functional impairment. Fewer reinfections were reported among vaccinated individuals; however, vaccination was not significantly associated with the presence of long COVID symptoms. Older age and comorbidities were correlated with higher risk. Conclusions: The findings underline the need for long-term occupational health strategies and individualized support programs for HCWs affected by long COVID, particularly in high-risk groups. Full article
(This article belongs to the Section Epidemiology & Public Health)
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15 pages, 636 KB  
Article
High Prevalence of Multidrug-Resistant Bacterial Colonization Among Patients and Healthcare Workers in a Rural Ethiopian Hospital
by Elena Hidalgo, Teresa Alvaredo-Carrillo, Josefina-Marina Gil-Belda, Clara Portela-Pino, Clara Bares-Moreno, Sara Jareño-Moreno, Paula de la Fuente, Lucía Platero and Ramón Pérez-Tanoira
Antibiotics 2025, 14(7), 717; https://doi.org/10.3390/antibiotics14070717 - 17 Jul 2025
Cited by 2 | Viewed by 2004
Abstract
Background/Objectives: Multidrug-resistant (MDR) bacterial colonization poses a significant risk for subsequent infections, especially within hospital environments. Healthcare workers can inadvertently transmit these MDR bacteria to vulnerable patients, exacerbating the problem. This study aimed to determine the colonization rates of MDR bacteria among patients [...] Read more.
Background/Objectives: Multidrug-resistant (MDR) bacterial colonization poses a significant risk for subsequent infections, especially within hospital environments. Healthcare workers can inadvertently transmit these MDR bacteria to vulnerable patients, exacerbating the problem. This study aimed to determine the colonization rates of MDR bacteria among patients and healthcare workers in a rural Ethiopian hospital with limited resources. Methods: Between 26 May and 6 June 2024, nasal, rectal, vagino-rectal exudate, and stool samples were collected from patients (n = 78) and healthcare workers (n = 11) at Gambo General Hospital (Oromia Region, Ethiopia). Samples were cultured on chromogenic media selective for methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus spp. (VRE), and carbapenemase-producing Enterobacteriaceae (CPE). Bacterial identification was performed using MALDI-TOF mass spectrometry (Bruker), antimicrobial susceptibility testing using the MicroScan WalkAway system (Beckman Coulter), and genotypic characterization with the MDR Direct Flow Chip kit (Vitro). Results: MRSA nasal colonization was detected in 43.3% of patients (13/30; 95% CI: 27.4–60.8%) and 27.3% of healthcare workers (3/11; 95% CI: 6.0–61.0%) (p = 0.73). Rectal (or stool) colonization by MDR bacteria was significantly higher in pediatric patients (85.0%, 17/20; 95% CI: 62.1–96.8%) than in adults (14.3%, 4/28; 95% CI: 5.7–31.5%) (p < 0.001). Notably, a high proportion of pediatric patients harbored Escherichia coli strains co-producing NDM carbapenemase and CTX-M ESBL, and VRE strains were also predominantly isolated in this group. Conclusions: This study reveals a concerningly high prevalence of MRSA and MDR Enterobacteriaceae, especially among children at Gambo Hospital. The VRE prevalence was also substantially elevated compared to other studies. These findings underscore the urgent need for strengthened infection control measures and antimicrobial stewardship programs within the hospital setting. Full article
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11 pages, 391 KB  
Article
Implementing a Novel Resident-Led Peer Support Program for Emergency Medicine Resident Physicians
by Kyra D. Reed, Alexandra E. Serpe, Alexandria P. Weston, Destiny D. Folk, Heather P. Kelker, Aloysius J. Humbert, Katie E. Pettit and Julie L. Welch
Behav. Sci. 2025, 15(7), 943; https://doi.org/10.3390/bs15070943 - 12 Jul 2025
Viewed by 2160
Abstract
Background: Residency training is a formative and rigorous experience, with burnout rates reported at 76%. Formal peer support groups have shown improvement in burnout among healthcare workers with anxiety and depression. Objective: Implement a peer support program for emergency medicine (EM) residents and [...] Read more.
Background: Residency training is a formative and rigorous experience, with burnout rates reported at 76%. Formal peer support groups have shown improvement in burnout among healthcare workers with anxiety and depression. Objective: Implement a peer support program for emergency medicine (EM) residents and characterize utilization of metrics by demographics, burnout rates of participants, and overall session impact. Methods: An IRB-approved, longitudinal, prospective cohort study of 73 EM and EM/Pediatrics residents post-graduate year (PGY) 1–5 from July 2021–June 2022 was performed. Resident peer leaders were trained using a novel curriculum to lead peer support groups. Residents were invited to participate in biweekly sessions, with optional pre- and post-session surveys measuring demographics, burnout, themes discussed, and how they felt after sessions (Patients’ Global Impression of Change scale). Results: There were 134 attendances over 20 sessions, averaging 6 residents per session. Of 73 total residents, 37 (50%) participated at least once. All levels of training were represented, with half being female, 20% underrepresented in medicine, and 14% LGBTQ+. Overall burnout rates were unchanged for first-time attendances (49%, n = 18) vs. recurrent (50%, n = 11). Females had higher burnout at both baseline (60%, n = 15) and recurrent sessions (69%, n = 13). Following sessions, 94% of participants reported feeling immediately better and 100% of leaders felt prepared leading peer support sessions. Conclusions: This study demonstrates that residents utilize peer support, with many returning more than once. Despite stable burnout rates, 94% of participants felt immediately better after the session, suggesting that peer support is a valuable resource for residents actively experiencing burnout. Full article
(This article belongs to the Special Issue Burnout and Psychological Well-Being of Healthcare Workers)
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19 pages, 933 KB  
Article
Practical Challenges in the Diagnosis of SARS-CoV-2 Infection in Children
by Alina Petronela Bouari-Coblișan, Claudia Felicia Pop, Valentina Sas, Adina Georgiana Borcău, Teodora Irina Bonci and Paraschiva Cherecheș-Panța
Nurs. Rep. 2025, 15(6), 196; https://doi.org/10.3390/nursrep15060196 - 30 May 2025
Viewed by 1223
Abstract
Background/Objectives: The COVID-19 pandemic, caused by SARS-CoV-2, required the rapid development of diagnostic tests. SARS-CoV-2, part of the betacoronavirus genus, shares characteristics with SARS-CoV-1, including its ability to survive on surfaces, facilitating the spread of the infection. This study analyzes the technique of [...] Read more.
Background/Objectives: The COVID-19 pandemic, caused by SARS-CoV-2, required the rapid development of diagnostic tests. SARS-CoV-2, part of the betacoronavirus genus, shares characteristics with SARS-CoV-1, including its ability to survive on surfaces, facilitating the spread of the infection. This study analyzes the technique of nasopharyngeal secretion collection for SARS-CoV-2 diagnosis and compares the accuracy of rapid antigen and molecular tests. Methods: This study had two components: study A assessed the healthcare personnel training in collecting nasopharyngeal secretions and the discomfort associated with applying a questionnaire. Study B compared rapid antigen test accuracy with RT-PCR among children, through a retrospective analysis. The data were statistically analyzed to assess compliance with the testing protocols. Results: In study A, 88 healthcare workers achieved an average compliance score of 7.60 out of 10 regarding the collection procedure. Over 70% of participants correctly followed the fundamental steps of the procedure. Many patients who underwent sample collection reported pain and symptoms such as coughing or sneezing. In study B, 198 pediatric patients were tested using rapid antigen tests, collected simultaneously with RT-PCR. The rapid tests showed a 50% sensitivity and 97.5% specificity. Conclusions: This study indicates that nasopharyngeal specimen collection techniques are based on international recommendations, but improvements could be made to reduce discomfort. Rapid antigen tests are helpful for screening due to their high specificity and negative predictive value. Continuous healthcare personnel training and the monitoring of diagnostic techniques remain essential in managing SARS-CoV-2 and other viral infections. Full article
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25 pages, 913 KB  
Article
Impact of the COVID-19 Pandemic on Musculoskeletal Disorder-Related Absenteeism Among Pediatric Healthcare Workers
by Maria Valentina Popa, Irina Luciana Gurzu, Claudia Mariana Handra, Bogdan Gurzu, Alina Pleșea Condratovici, Mădălina Duceac (Covrig), Eva Maria Elkan, Dana Elena Mîndru, Vlad Andrei Dabija and Letiția Doina Duceac
Healthcare 2025, 13(10), 1116; https://doi.org/10.3390/healthcare13101116 - 11 May 2025
Cited by 7 | Viewed by 2655
Abstract
Background and Objectives: Musculoskeletal disorders (MSDs) are a leading cause of absenteeism among healthcare workers (HCWs), impacting healthcare delivery. Pediatric HCWs face specific physical demands such as lifting and awkward postures. While absenteeism rose during the COVID-19 pandemic, its effects on pediatric MSD-related [...] Read more.
Background and Objectives: Musculoskeletal disorders (MSDs) are a leading cause of absenteeism among healthcare workers (HCWs), impacting healthcare delivery. Pediatric HCWs face specific physical demands such as lifting and awkward postures. While absenteeism rose during the COVID-19 pandemic, its effects on pediatric MSD-related leave remain unclear. This study examined MSD-related absenteeism trends among pediatric HCWs in a Romanian hospital across the pre-pandemic (2017–2019), pandemic (2020–2021), and post-pandemic (2022–2023) periods. Materials and Methods: We conducted a retrospective observational study using records from the hospital’s occupational health database. We included all HCWs who took MSD-related leave during 2017–2023. Diagnoses included arthropathies, dorsopathies, other osteoarticular/connective tissue disorders, and acute trauma or fractures. We used chi-square tests, ANOVA, and regression models to identify trends and predictors. Results: A total of 3388 cases were analyzed. Post-pandemic absenteeism increased significantly (40.1%), especially among women (86.8%), nurses (46.7%), and workers aged ≥46 (62.7%). A seasonal shift was observed, with spring peaks (March 9.7% and May 9.9%) replacing the pre-pandemic autumn peaks (October 11.9% and November 12.8%). The regression models identified age, occupation, and diagnosis type as significant predictors of leave duration. Conclusions: MSD-related absenteeism rose post-pandemic and showed altered seasonal patterns. Occupational and demographic predictors identified through a multivariate analysis highlight the need for anticipatory, evidence-based strategies to support pediatric HCWs, enhance workforce resilience, and sustain healthcare performance. Full article
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11 pages, 844 KB  
Article
Treatment-Decision Algorithm of Child TB: Evaluation of WHO Algorithm and Development of Indonesia Algorithm
by Rina Triasih, Finny Fitry Yani, Diah Asri Wulandari, Betty Weri Yolanda Nababan, Muhammad Buston Ardiyamustaqim, Fransiska Meyanti, Sang Ayu Kompiyang Indriyani, Tiffany Tiara Pakasi and Ery Olivianto
Trop. Med. Infect. Dis. 2025, 10(4), 106; https://doi.org/10.3390/tropicalmed10040106 - 14 Apr 2025
Cited by 2 | Viewed by 4090
Abstract
Clinical algorithms for child tuberculosis (TB) are a valuable guide for healthcare workers to initiate treatment. We evaluated the agreement of pediatric TB diagnosis using the current Indonesia diagnostic algorithms with the 2022 WHO treatment decision algorithm and developed a new Indonesia algorithm [...] Read more.
Clinical algorithms for child tuberculosis (TB) are a valuable guide for healthcare workers to initiate treatment. We evaluated the agreement of pediatric TB diagnosis using the current Indonesia diagnostic algorithms with the 2022 WHO treatment decision algorithm and developed a new Indonesia algorithm for child TB based upon our findings and expert opinion. We conducted a retrospective study at 10 hospitals in Indonesia, involving children (0–10 years), who were evaluated for TB diagnosis in 2022. A panel of child TB experts used participants’ records to make a diagnosis using the 2022 WHO algorithm and the 2016 Indonesian algorithm. We assessed agreement between the diagnosis made by the attending doctor and those determined by the expert panel. A new Indonesia guideline was developed based on the findings and consensus of various stakeholders. Of 523 eligible children, 371 (70.9%) were diagnosed with TB by the attending doctors, 295 (56.4%) by the WHO algorithm, and 246 (47%) by the Indonesia algorithm. The Cohen’s Kappa of TB diagnosis was: attending doctor vs. WHO algorithm (0.27), attending doctor vs. Indonesia algorithm (0.45), and WHO algorithm vs. Indonesia algorithm (0.42). A review of both algorithms revealed challenges for implementation. An algorithmic approach for child TB diagnosis may not be universally applicable or implementable due to variable access to diagnostic tests and the wide variety of clinical presentations. Full article
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12 pages, 1418 KB  
Article
Burnout in Pediatric Oncology: Team Building and Clay Therapy as a Strategy to Improve Emotional Climate and Group Dynamics in a Nursing Staff
by Antonella Guido, Laura Peruzzi, Matilde Tibuzzi, Serena Sannino, Lucia Dario, Giulia Petruccini, Caterina Stella, Anna Maria Viteritti, Antonella Becciu, Francesca Bianchini, Deborah Cucculelli, Carmela Di Lauro, Ivana Paglialonga, Sabina Pianezzi, Roberta Pistilli, Sabrina Russo, Paola Adamo, Daniela Pia Rosaria Chieffo, Dario Talloa, Alberto Romano and Antonio Ruggieroadd Show full author list remove Hide full author list
Cancers 2025, 17(7), 1099; https://doi.org/10.3390/cancers17071099 - 25 Mar 2025
Cited by 2 | Viewed by 2972
Abstract
Healthcare professionals in pediatric oncology are at a high risk of burnout. Art therapy is being increasingly recognized as a potential tool for reducing stress and improving emotional well-being. The Art-Out pilot project aimed at nursing staff was initiated in a pediatric oncology [...] Read more.
Healthcare professionals in pediatric oncology are at a high risk of burnout. Art therapy is being increasingly recognized as a potential tool for reducing stress and improving emotional well-being. The Art-Out pilot project aimed at nursing staff was initiated in a pediatric oncology unit. The staff members participating in the project were guided in a team-building course integrated with art and clay therapy, aiming to reduce burnout levels, improve emotional climate, and strengthen resilience. Methods: Burnout levels were assessed through the Maslach Burnout Inventory (MBI), alexithymia was measured with the Toronto Alexithymia Scale (TAS-20), and emotional regulation difficulties were evaluated through the Difficulties in Emotion Regulation Scale (DERS); these tests were assessed before (T0) and after (T1) the team-building course (Art-Out project). Results: Data analysis showed a significant reduction in burnout, alexithymia, and emotional dysregulation, highlighting the positive impact of this approach in improving team dynamics and emotional management. Conclusions: Our study confirms the high risk of burnout, alexithymia, and emotional dysregulation among pediatric oncology healthcare workers, underscoring the need for targeted interventions to prevent and mitigate these risks. Full article
(This article belongs to the Special Issue Quality of Life and Management of Pediatric Cancer)
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27 pages, 7425 KB  
Article
Dynamics of Absences Due to Respiratory Infections, Including COVID-19, Among Medical Staff in a Regional Pediatric Hospital
by Maria Valentina Popa, Irina Luciana Gurzu, Dana Elena Mîndru, Bogdan Gurzu, Claudia Mariana Handra, Elkan Eva-Maria, Iulia Olaru, Dana Teodora Anton-Păduraru, Cezarina Warter and Letiția Doina Duceac
Healthcare 2025, 13(5), 563; https://doi.org/10.3390/healthcare13050563 - 5 Mar 2025
Cited by 6 | Viewed by 3088
Abstract
Background: Respiratory infections pose a significant public health challenge, particularly among healthcare workers (HCWs). The COVID-19 pandemic exacerbated absenteeism due to respiratory illnesses, affecting healthcare workforce stability. Identifying factors influencing absenteeism is crucial for workforce resilience and effective care. Methods: This [...] Read more.
Background: Respiratory infections pose a significant public health challenge, particularly among healthcare workers (HCWs). The COVID-19 pandemic exacerbated absenteeism due to respiratory illnesses, affecting healthcare workforce stability. Identifying factors influencing absenteeism is crucial for workforce resilience and effective care. Methods: This retrospective longitudinal study analyzed HCW absenteeism due to respiratory diseases from 2017 to 2023 at the “Sf. Maria” Children’s Emergency Hospital in Iași, Romania. Data from 3827 HCWs were examined, including demographic and occupational variables (age, gender, job role) and disease types. Statistical analyses (chi-square tests, ANOVA, and regression models) were conducted using SPSS to assess absenteeism trends and associated risk factors. Results: Sick leave peaked in 2020 (8322 days) and remained high in 2021 (8134 days), gradually decreasing in 2022–2023 but not returning to pre-pandemic levels (~5000 days/year). Nurses accounted for most leave days, while male staff and HCWs aged 41–50 were most affected. Seasonal variations showed higher absenteeism in transitional months and lower rates in summer. COVID-19 was the leading cause of absenteeism during the pandemic, with quarantine measures further increasing sick leave duration. Conclusions: Pediatric hospitals must strengthen infection control measures to protect HCWs and sustain care continuity. Preventive actions such as immunization, staff training, and health monitoring are critical in reducing absenteeism, maintaining a resilient workforce, and ensuring quality care during health crises. Full article
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17 pages, 3334 KB  
Article
Longitudinal Surveillance of COVID-19 Antibodies in Pediatric Healthcare Workers
by Dunia Hatabah, Sneh Lata Gupta, Grace Mantus, Patrick Sullivan, Stacy Heilman, Andres Camacho-Gonzalez, Deborah Leake, Mimi Le, Mark Griffiths, Carson Norwood, Samuel Shih, Rawan Korman, Giorgi Maziashvili, Chris A. Rees, Laura Benedit, Bridget A. Wynn, Mehul Suthar, Miriam B. Vos, Jens Wrammert and Claudia R. Morris
Vaccines 2025, 13(2), 163; https://doi.org/10.3390/vaccines13020163 - 7 Feb 2025
Cited by 1 | Viewed by 2027
Abstract
Background: Vaccines against COVID-19 target the spike protein. There is minimal information on longitudinal COVID-19 immune profiling in recovered versus naïve and vaccinated versus non-vaccinated healthcare workers (HCWs). Methods: This is a prospective longitudinal observational cohort of pediatric HCWs (pHCWs) conducted during 2020–2022 [...] Read more.
Background: Vaccines against COVID-19 target the spike protein. There is minimal information on longitudinal COVID-19 immune profiling in recovered versus naïve and vaccinated versus non-vaccinated healthcare workers (HCWs). Methods: This is a prospective longitudinal observational cohort of pediatric HCWs (pHCWs) conducted during 2020–2022 at an academic center, exploring the impact of COVID-19 vaccination on immunoglobulin G (IgG) antibody titers over time and cross-reactivity with other coronaviruses, including SARS-CoV-1, MERS-CoV, and seasonal coronaviruses (HCoV-HKU1 and HCoV-OC43). Results: A total of 642 pHCWs initially enrolled, and 337 participants had repeat IgG titers measured post-vaccine and post-booster. Most participants were female, median age range of 31–40 years. Anti-spike was higher in all vaccinated individuals versus non-vaccinated (p < 0.0001) and naïve versus infected (p < 0.0001). A single dose of vaccine was sufficient to attain maximum titers in recovered participants versus naïve who received both doses of vaccine. Anti-spike titers dropped significantly at 9 months after the primary series, whereas sustained anti-spike titers were observed at 9 months post-booster. Conclusions: All vaccinated pHCWs developed antibodies to spike. COVID-19 infection and/or vaccination yielded antibodies that cross-reacted to SARS-CoV-1, MERS-CoV, HCoV-HKU1, and HCoV-OC43. Anti-spike titers were more durable post-booster compared to the primary series. Longitudinal immune profiling of COVID-19 responses provides vital data to shape public health policies, optimize vaccine strategies, and strengthen pandemic preparedness. Full article
(This article belongs to the Special Issue 2nd Edition of Antibody Response to Infection and Vaccination)
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9 pages, 220 KB  
Article
Infectious Risk in Pediatric Emergency Departments in Italy: A Survey by the Italian Society for Pediatric Emergency and Urgent Medicine (SIMEUP) on Available Preventive and Diagnostic Tools
by Sonia Bianchini, Stefania Formicola, Lidia Decembrino, Laura Ladetto, Maria Novella Pullano, Cosimo Neglia, Danilo Buonsenso, Stefania Zampogna and Susanna Esposito
J. Clin. Med. 2024, 13(24), 7762; https://doi.org/10.3390/jcm13247762 - 19 Dec 2024
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Abstract
Background/Objectives: The COVID-19 pandemic has emphasized the importance of preparedness in preventing the spread of infectious diseases, especially in Emergency Departments (EDs), where initial patient assessments and triage occur. This study aims to evaluate the current practices and available tools for infection control [...] Read more.
Background/Objectives: The COVID-19 pandemic has emphasized the importance of preparedness in preventing the spread of infectious diseases, especially in Emergency Departments (EDs), where initial patient assessments and triage occur. This study aims to evaluate the current practices and available tools for infection control in Pediatric EDs across Italy, focusing on the differences between various hospital types and regional settings. Methods: A cross-sectional national survey was conducted in February 2022, targeting healthcare workers in Pediatric EDs across Italy. The survey, distributed via the Italian Society for Pediatric Emergency and Urgent Medicine (SIMEUP) mailing list, collected data on infection control measures, including the availability of hand hygiene stations, personal protective equipment, disinfection protocols, and the use of rapid diagnostic tests. Results: A total of 80 questionnaires were completed from 119 (67.2%) different ERs. The majority of respondents were from Northern Italy (47.5%) and worked in hospitals with 24 h pediatric assistance (48.8%). Less than half of non-pediatric hospitals had separate access for children, potentially exposing them to adult pathogens. Across all settings, basic infection control measures, such as providing masks and hand gel, were widely implemented. However, significant differences were observed in the availability of social distancing, informational materials, and dedicated pediatric pathways, with I level assistance hospitals less likely to have these resources. Rapid diagnostic tests were available in most settings, but the focus was predominantly on SARS-CoV-2, despite other respiratory pathogens’ relevance in pediatric care. Conclusions: Strengthening preparations for future pandemics will be crucial in enhancing the resilience of healthcare systems and ensuring the safety of both patients and healthcare workers in the face of emerging infectious threats. Full article
(This article belongs to the Section Clinical Pediatrics)
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