Search Results (314)

Background: Emotional intelligence (EI), particularly the ability to regulate one’s emotions, is a key protective factor against stress and burnout in high-demand occupations, including leadership and healthcare. Compassion and gratitude practices have been proposed as brief, scalable methods to strengthen emotion regulation, yet empirical evidence from randomised controlled trials remains limited. Objective: This study evaluated whether a four-week, self-directed online programme combining daily loving-kindness meditation and gratitude journaling improves EI among leaders. Methods: Forty-five leaders in Germany from diverse occupational sectors were recruited via LinkedIn and Xing and were randomised using a computer-generated random sequence to an intervention or wait-list control group. EI was measured pre- and post-intervention with the Emotional Competence Questionnaire (EKF), comprising recognising one’s own feelings (RU), recognising others’ feelings (RO), regulating one’s own feelings (RC; primary outcome), and expressing feelings (RE). Adherence was reported in categorical form (e.g., daily, 3–5×/week, 1–2×/week). Treatment effects were tested using mixed-design ANOVAs. Results: A significant Group × Time interaction emerged for emotion regulation (RC), indicating greater improvement in the intervention group compared with the control group. No significant interaction effects were found for RU, RO, or RE. Adherence data did not permit dose–response analysis. Conclusions: A brief, self-directed online compassion and gratitude programme selectively improved emotion regulation—the EI facet most strongly linked to stress buffering and resilience. Although effects did not extend to other EI dimensions, findings suggest that low-threshold digital practices may strengthen a core emotional skill relevant to psychological well-being in leadership roles. Because the sample did not primarily comprise healthcare professionals, implications for healthcare settings re-main conceptual; targeted trials in clinical populations are warranted. Full article

Background: Chronic obstructive pulmonary disease (COPD) is a progressive respiratory condition with significant economic burden, morbidity, and mortality rates worldwide. In the Kingdom of Saudi Arabia (KSA), 4.2% of adults 40 years and older have COPD, with a higher prevalence in men and older populations. Key risk factors include smoking, air pollution, occupational exposures, and genetics. COPD coexists with cardiovascular disease (CVD) often, making diagnosis and management more difficult. This study proposes two referral algorithms to optimize care for COPD patients with coexisting CVD in the KSA. Methods: A nine-member cardiopulmonary task force reviewed pertinent literature, guidelines, and held virtual meetings from April to August 2025. Every algorithmic component was iteratively refined; consensus was reached when at least 80% of participants agreed, and items not reaching this threshold were revised until full agreement was reached. Results: According to the cardiology-to-pulmonology algorithm, patients who have unidentified respiratory symptoms or COPD risk factors undergo spirometry assessment and, if confirmed, are referred to pulmonology for diagnostic confirmation, phenotyping, and treatment, including triple fixed-dose combination therapy (TFDC) when necessary. On the other hand, the pulmonology-to-cardiology algorithm directs the evaluation of CVD risk factors and comorbidities using clinical evaluation, electrocardiogram, echocardiography, and biomarker testing, for cardiology referral. Conclusions: By establishing bidirectional referral pathways, morbidity and healthcare burden can be decreased, early detection can be improved, and multidisciplinary management can be strengthened. Future research should assess the feasibility, cost-effectiveness, and real-world impact within KSA’s healthcare system. Full article

Underground mining environments present elevated occupational health risks, primarily due to substantial exposure to diesel exhaust emissions within confined and poorly ventilated spaces. This study assesses the real-world performance of two advanced retrofit emission control systems—Proventia NOxBuster and Purifilter—installed on underground mining trucks operating in a Spanish mine. Emissions of carbon monoxide (CO), nitric oxide (NO), and nitrogen dioxide (NO₂) were quantified using a Testo 350 multigas analyser, while ultrafine particle (UFP) concentrations were measured with an Engine Exhaust Particle Sizer (EEPS-3090) equipped with a thermodiluter. Controlled tests under both idling and acceleration conditions revealed substantial reductions in pollutant emissions: CO decreased by 60–98%, NO by 51–92%, and NO₂ by 20–87%, depending on the system and operational phase. UFP concentrations during idling dropped by approximately 90%, from 542,000 particles/cm³ in untreated trucks to below 50,000 particles/cm³ in retrofitted vehicles. Under acceleration, the Proventia NOxBuster achieved reductions exceeding 95%. Conversely, Purifilter-equipped trucks exhibited a counterintuitive increase in UFPs within the 5.6–40 nm range, potentially due to ammonia slip events during selective catalytic reduction (SCR). Despite these discrepancies, both systems demonstrated considerable mitigation potential, albeit highly dependent on exhaust temperature (optimal: 200–450 °C), urea dosing precision, and maintenance protocols. This work underscores the necessity of in situ performance verification, regulatory vigilance, and targeted intervention strategies to protect underground workers effectively. Further investigation is warranted into the long-term health benefits, system durability, and nanoparticle emission dynamics under variable load conditions. Full article

Radiology services play a vital role in modern healthcare, yet disparities in access and concerns about occupational radiation exposure remain understudied in many countries, including Kazakhstan. This study evaluates national trends in diagnostic imaging services, workforce distribution, and radiation-related anxiety among medical personnel. We analyzed national diagnostic imaging infrastructure and workforce data from 2018–2024. Individual radiation exposure data (n = 177) were obtained from dosimetry records in Astana’s medical facilities. Additionally, a cross-sectional survey (n = 324) was conducted using the Spielberger–Hanin Anxiety Scale to assess radiation-related anxiety and associated factors. Between 2018 and 2024, the number of CT rooms in Kazakhstan more than doubled from 162 to 358 (+121%), while X-ray examinations declined from 20.6 to 14.6 million (−29.2%) and fluorography dropped by 67.7%. CT scans increased over threefold, from 491,738 to 1.6 million. Radiologists grew from 3529 to 4511 (+27.8%), and ultrasound doctors from 1396 to 2178 (+56.1%). Interventional physicians had the highest quarterly radiation dose (0.65 ± 0.58 mSv, p = 0.001). Among radiology professionals, 32% reported anxiety related to occupational exposure. Anxiety was significantly associated with not using aprons (58% vs. 27%, p < 0.001), lack of dosimeter use (27% vs. 12%, p = 0.001), and inadequate safety training (27% vs. 6%, p < 0.001). Spielberger–Hanin scores ≥ 45 indicated high levels of situational (58%) and personal (56%) anxiety in this group. Kazakhstan’s diagnostic radiology capacity has grown rapidly, especially in CT availability, yet regional disparities and occupational anxiety remain critical concerns. Targeted workforce distribution, improved protective practices, and enhanced radiation safety education are urgently needed. Full article

The comprehensive utilization of hazardous waste may introduce heavy metals, organic pollutants, etc., into products, resulting in secondary pollution. The environmental risk assessment method for hazardous waste resource utilization products is an important technical means of environmental management. We have established a standardized method for hazard identification, exposure evaluation and risk characterization. This study selects waste sulfuric acid generated in the integrated circuit industry as the object and investigates the use of waste sulfuric acid to react with aluminum hydroxide to produce liquid aluminum sulfate flocculant, as well as the environmental risks brought to practitioners and the potential relevant population in the sewage treatment process. By analyzing sulfuric acid and aluminum hydroxide, toxic substances such as nitrate ions, fluorides, As, Pb, Cr, Hg, Cd, etc., were identified. Through exposure scenario analysis, the exposure levels of occupational and non-occupational populations were determined. Based on the dose–response relationship data in the IRIS database of the United States and the carcinogenic and non-carcinogenic data of skin contact routes, it was suggested that chromium and its compounds were the main contributors to carcinogenic risk, and cadmium, its compounds, and mercuric chloride were the contributors to the non-carcinogenic risk. The total carcinogenic risk to human health in occupational populations was 5.31 × 10⁻⁵, and the total non-carcinogenic risk was 8.80 × 10⁻¹. The total carcinogenic risk to human health in non-occupational populations was 1.73 × 10⁻¹⁵, and the total non-carcinogenic risk was 1.23 × 10⁻¹¹. Based on this research, it is clear that the production of liquid aluminum sulfate flocculants from waste sulfuric acid generated in the integrated circuit industry has a low impact on occupational and other populations during use, and the environmental risks generated by this product are acceptable even under the most dangerous conditions. Full article

Melanoma is a highly aggressive skin cancer primarily linked to ultraviolet (UV) radiation. However, the potential role of ionizing radiation from radiotherapy in melanoma development remains unclear. This review synthesizes data from epidemiologic studies and case reports on melanoma after radiation exposure. Evidence indicates that childhood radiotherapy, even at low doses, is associated with an increased melanoma risk, plausibly reflecting the heightened radiosensitivity of developing melanocytes. Occupational radiation exposure, particularly in earlier eras with insufficient shielding, also appears to elevate risk. In patients exposed to radiation in adulthood, findings are mixed: large population datasets suggest a modest increase in melanoma following therapeutic radiation, whereas some case–control analyses do not demonstrate a clear dose–response relationship. UV radiation promotes melanomagenesis through direct DNA photoproducts driving characteristic C>T transitions at dipyrimidine sites, alongside oxidative stress and local immune modulation that facilitate malignant transformation. Collectively, individuals with prior radiotherapy, especially those irradiated in childhood, should be considered at increased melanoma risk and may benefit from long-term, targeted surveillance of irradiated fields. Awareness of this association between radiation exposure and melanoma may also support clinicopathologic correlation during the diagnostic evaluation of melanocytic lesions. Future work should define dose–response relationships in contemporary radiotherapy methods, characterize molecular signatures of ionizing radiation-associated melanomas, and establish evidence-based surveillance strategies for high-risk cohorts. Full article

Indoor exposure to polybrominated diphenyl ethers (PBDEs), particularly those bound to fine particulate matter (PM₁, particles < 1 µm), may pose a health concern, especially in light of prolonged indoor occupancy and the capacity of ultrafine particles to reach the lower respiratory tract. This study investigates indoor exposure to PBDEs associated with PM₁ in residential homes in Zagreb, Croatia, across warm and cold seasons. BDE-47 was consistently detected in all samples, while BDE-183 was consistently absent. Elevated concentrations and increased detection frequencies of BDE-99 and BDE-100 were observed during the colder season. Consequently, total PBDE (ΣPBDE) levels in the cold season were approximately 2.5 times higher than in the warm season. Although estimated daily inhalation intakes were below established oral reference doses, the potential for deep pulmonary deposition and systemic distribution underscores the need for further investigation. These findings represent the first reported data on indoor PM₁-associated PBDEs in Europe, emphasizing the impact of seasonal dynamics on inhalation exposure due to variation on indoor contaminant levels. Full article

We examined whether synchronizing and analyzing three data sources, active personal dosimeter (APD) information, in-room monitoring camera footage, and the operator’s main angiography panel video, could identify opportunities to reduce occupational radiation exposure during cerebral angiography without therapeutic intervention. We analyzed the behavior of eight physicians and radiation doses measured outside the lead apron during 12 diagnostic cerebral angiography procedures performed between January and April 2024. Appropriate use of a ceiling-suspended radiation protective shield (CSRPS) was associated with approximately 70% exposure reduction. In addition, exposure during femoral arteriography (catheter advancement from femoral artery puncture to the aortic arch) accounted for approximately 50% of the total exposure, identifying both as effective intervention points. This approach identified operators’ incorrect use of radiation protection equipment and enabled clear feedback to operators on areas for improvements in radiation protection practices. Full article

While reducing industrial environmental impacts, it is essential to verify that the perceived improvements do not cause unexpected side effects. In the construction materials sector, certain circular economy practices may potentially increase the exposure from natural radioactivity due to the elevated radionuclide content in processed naturally occurring radioactive material (NORM). This study presents the development of a life cycle impact assessment (LCIA) methodology accounting for NORM impacts in construction material life cycles from cradle to use. The methodology builds upon the LCA-NORM life cycle assessment framework previously established by the research group. The novel contributions include enhancements in (1) the dose units, (2) the use-stage exposure scenario, (3) the inclusion of radionuclide inhalation as an occupational exposure pathway and (4) the revisions of key parameters, including the dose conversion coefficients (DCCs). The updated characterisation factors yielded more conservative values at the use stage (e.g., 7 times higher exposure under pessimistic conditions due to radon inhalation) compared to the previous LCA-NORM outputs. An important advancement is the implementation of the new methodology in a novel custom-developed Python package (i.e., NORMIA) to integrate the custom elementary flows into LCA calculations of the Python library Brightway v.2.5. NORMIA generates characterisation factors that quantify the equivalent stochastic risk for human health and non-human biota per unit radionuclide emission and activity, based on user-defined inputs such as construction material type and density. With this study, a more holistic and accurate assessment of the environmental sustainability of construction materials is targeted. Full article

Prostatic artery embolization (PAE) is increasingly used as a primary minimally invasive treatment modality for lower urinary tract symptoms associated with benign prostatic hyperplasia. As a complex, fluoroscopic-guided endovascular procedure, PAE necessitates a significant use of ionizing radiation, raising important safety considerations for both patients and medical personnel. The objective of this review is to first summarize the procedural and anatomic fundamentals of PAE, and then to provide a comprehensive overview of the current literature on radiation dosimetry, establish contemporary benchmarks for dose metrics, and present an evidence-based guide to practical dose optimization strategies. Through a thorough review of published clinical studies, this article synthesizes reported values for key radiation indices, including Dose Area Product (DAP), Cumulative Air Kerma (CAK), and Fluoroscopy Time (FT). Furthermore, we will critically examine factors influencing dose variability—including patient complexity, procedural technique, and imaging technology—and will provide a practical, clinically oriented guide to implementing dose-saving measures. Ultimately, this review concludes that while PAE involves a non-trivial radiation burden, a thorough understanding and application of optimization principles can ensure the procedure is performed safely, reinforcing its role as a valuable therapy for BPH. Full article

Occupational radiation exposure in nuclear medicine presents complex spatial and temporal patterns due to the use of unsealed radiopharmaceuticals and prolonged proximity to patients. Traditional passive dosimetry provides only cumulative dose values, limiting its usefulness in identifying task-specific exposures or capturing momentary fluctuations. This study applied a real-time dosimetry system capable of second-by-second measurements, combined with time-series analysis, to evaluate staff exposure during myocardial perfusion imaging using technetium-99m. Dosimeters were placed on the left and right sides of the neck and head of two radiological technologists. Dose rates were continuously recorded throughout the injection and imaging phases. The right side of the neck received the highest cumulative and peak dose rates among all sites. Although no significant difference in total dose was observed between the injection and imaging phases, specific high-exposure events were detected. Notably, ECG lead placement and post-injection handling produced dose spikes. A positive correlation was found between administered activity and dose rate at neck-level sites but not at head-level sites. These findings demonstrate the value of real-time dosimetry in identifying procedural actions associated with elevated exposure. Time-series analysis further contextualized these peaks, supporting improved task-specific protective strategies beyond the capabilities of conventional dosimetry. Full article

Open-plan offices have established themselves as economically efficient working environments and promote communication. Zoned lighting concepts have proven to be particularly energy-efficient and are determined by the respective occupancy profile. Due to their size, open-plan offices usually have very different levels of daylight availability depending on their position in the room, which affects the light doses per workstation. It is unclear what influence the distribution of users in the room has on the respective target values. This study therefore examines the effects of a variation in the spatial distribution of users in a real open-plan office regarding the three target values of communication distances, daily light doses, and artificial light energy requirements. Statistical methods are used to examine how a user distribution optimized for one target variable affects the other target variables. Since optimizing user distribution is an NP-hard combinatorial problem, heuristic methods are used. The results show that optimized user distribution improves only one target variable. There are no consistently strong correlations between the optimization of communication distances, energy savings, and achievable daily light doses. The work thus contributes to the holistic design of sustainable, user-centered working environments. This research is an example of a living lab case study with optimization-based modeling, emphasizing its exploratory nature rather than controlled experimental inference. Full article

Pesticides are used in agriculture to protect crops from disease. Among these, the herbicide glyphosate, the insecticide deltamethrin, and the fungicides propamocarb and tebuconazole are approved for use in Europe. These pesticides, along with their metabolites, have been detected in the environment including in food and water sources. Human biomonitoring studies have confirmed the presence of these compounds in biological samples, indicating persistent exposure even among the general population, unrelated to agricultural occupations. Consequently, numerous studies have investigated the health effects of these four pesticides and their metabolites. This review focuses on their impacts on gut health primarily the gut microbiota, inflammation, metabolism, cancer and gut–brain axis. Epidemiological studies were included to assess health risks among various groups including adults, children and pregnant women. Animal and in vitro models have been employed to explore in a more controlled and targeted way the physiological and biochemical effects observed in epidemiological studies. Despite some controversy, pesticides and their metabolites have been linked to gut dysbiosis, inflammatory bowel disease (IBD), metabolic disorders, cancer and neurodevelopmental disorders. Mechanistically, these pesticides influence gut microbiome composition, sugar and lipid metabolism, oxidative stress, inflammatory pathways, cell death, oncogenic signalling pathways, endocrine disruption, and epigenetics. However, further studies are needed to confirm these risks and health impacts, particularly concerning low-dose, long-term exposure as experienced by the general population. A comprehensive investigation of these effects is essential, incorporating dietary factors, age, sex, health status, and the cumulative impact of multiple pesticides, to develop a thorough risk assessment. Full article

Idiopathic pulmonary fibrosis (IPF) is currently defined as a progressive fibrosing interstitial lung disease (ILD) associated with a histopathologic and radiologic pattern of usual interstitial pneumonia (UIP). The relationship between IPF and particles is described, and a pathogenesis for the disease is proposed based on an association with these exposures. In clinical studies and epidemiological investigations, the majority of IPF diagnoses are associated with particle exposures. Cigarette smoking presents the greatest particle challenge in any society, and a relationship with IPF has repeatedly been demonstrated. Environmental exposures to particles other than cigarette smoking, including biomass fuel smoke and ambient air pollution, as well as numerous occupational particle exposures, have also been associated with IPF. The pathogenesis of the disease includes a complexation and sequestration of cell iron at the particle surface, which results in a functional cell deficiency of the requisite metal. In response to the insufficiency of metal in cells, there is the synthesis of biopolymers, including exopolysaccharides (e.g., hyaluronic acid), which accumulate in the extracellular matrix. These biopolymers complex iron and, following depolymerization, facilitate the delivery of the metal intracellularly via receptor-mediated uptake. This process reverses the functional iron deficiency introduced by the particle. Pulmonary fibrosis after particle exposure reflects a response to the modification of a functional intracellular iron deficiency in the lower respiratory tract. The temporal and spatial heterogeneity of IPF results from a dose–response with retained particles and reversibility of the fibrosis. Full article

Background: Radiation exposure in the cardiac catheterization laboratory remains a critical occupational hazard for interventional cardiologists and staff, contributing to orthopedic injuries, cataracts, and malignancy. In parallel, procedural complexity continues to increase, demanding both precision and safety. Robotic-assisted percutaneous coronary intervention (R-PCI), alongside advanced shielding systems and imaging integration, has emerged as a transformative strategy to minimize radiation and enhance operator ergonomics. Objective: This state-of-the-art review synthesizes the current clinical evidence and technological advances that support a radiation-reduction paradigm in percutaneous coronary intervention (PCI), with a particular focus on the role of R-PCI platforms, procedural modifications, and emerging shielding technologies. Methods: We reviewed published clinical trials, registries, and experimental studies evaluating robotic PCI platforms, contrast and radiation dose metrics, ergonomic implications, procedural efficiency, and radiation shielding systems. Emphasis was given to the integration of CT-based imaging (coronary computed tomography angiography—CCTA, fractional flow reserve computed tomography—FFR-CT) and low-dose acquisition protocols. Results: R-PCI demonstrated technical success rates of 81–100% and clinical success rates up to 100% in both standard and complex lesions, with significant reductions in operator radiation exposure (up to 95%) and procedural ergonomic burden. Advanced shielding technologies offer radiation dose reductions ranging from 86% to nearly 100%, while integration of (CCTA), (FFR-CT), and Artificial Intelligence (AI) -assisted procedural mapping facilitates further fluoroscopy minimization. Robotic workflows, however, remain limited by lack of device compatibility, absence of haptic feedback, and incomplete integration of physiology and imaging tools. Conclusions: R-PCI, in combination with shielding technologies and imaging integration, marks a shift towards safer, radiation-minimizing interventional strategies. This transition reflects not only a technical evolution but a philosophical redefinition of safety, precision, and sustainability in modern interventional cardiology. Full article