A proper model of Web service non-functional properties is the key foundation to the evaluation of non-functional properties of Adaptive Service Based Software (ASBS) systems. As the environment in which a Web service is deployed may keep changing, e...
In software engineering, there must be clarity in communication among interested parties to elicit the requirements aimed at software development through frameworks to achieve the behaviors expected by the software. Problem: A lack of clarity in the...
To date, unquestionable efforts have been made, both in academia and industry, to facilitate the development of functional requirements (FRs) throughout the different phases of the software development life cycle (SDLC). Functional requirements are u...
Background/Objectives: Non-functional oral habits, such as unilateral chewing, bruxism, and clenching, may exacerbate temporomandibular disorder (TMD) symptoms and affect skeletal morphology in patients with dentofacial deformities. This study aimed...
Background/Objectives: Pituitary apoplexy (PA) is a rare medical emergency characterized by the sudden onset of symptoms resulting from hemorrhage and/or infarction within the pituitary gland. Precipitating factors include the use of dopamine agonist...
As a result of the speed and availability of the Internet, mobile devices and apps are in widespread usage throughout the world. Thus, they can be seen in the hands of nearly every person, helping us in our daily activities to accomplish many tasks w...
Background and Objective: Non-functioning pituitary neuroendocrine tumors (NF-PitNETs) represent a heterogeneous tumor type that lacks effective medical treatment. MDM2, the main negative regulator of p53, binds to and forms a stable complex with p53...
Recurrence after resection in patients with non-functional pancreatic neuroendocrine tumors (NF-pNET) has a considerable impact on overall survival. Accurate risk stratification will tailor optimal follow-up strategies. This systematic review assesse...
Background and Objectives: A magnetic resonance imaging (MRI) scan is part of the diagnostic protocol in pituitary adenoma patients. The goal of the present study is to present and analyse the MRI appearances of the sphenoid sinus (SS) in patients wi...
To evaluate the secretory function of adrenal incidentaloma, this study explored the usefulness of a contrast-enhanced computed tomography (CECT)-based radiomics model for distinguishing aldosterone-producing adenoma (APA) from non-functioning adrena...
Background: The differentiation of pheochromocytoma (PCC) from other adrenal lesions, particularly in incidentalomas with non-benign radiological characteristics (size > 4 cm or density > 10 HU), remains a clinical challenge. The study aimed to...
Post-operative tumour progression in patients with non-functioning pituitary neuroendocrine tumours is variable. The aim of this study was to use machine learning (ML) models to improve the prediction of post-operative outcomes in patients with NF Pi...
Internet of Medical Things (IoMT) is a rapidly evolving field with the potential to bring significant changes to healthcare. While several surveys have examined the structure and operation of these systems, critical aspects such as interoperability,...
Post-operative endocrine outcomes in patients with non-functioning pituitary adenoma (NFPA) are variable. The aim of this study was to use machine learning (ML) models to better predict medium- and long-term post-operative hypopituitarism in patients...
The primary treatment for non-functioning pituitary tumors (NFPTs) is surgery, but it is often unsuccessful. Previous studies have reported that NFPTs express receptors for somatostatin (SST1-5) and dopamine (DRDs) providing a rationale for the use o...
Purpose: To assess the risk of developing autonomous cortisol secretion (ACS) and tumour growth in non-functioning adrenal incidentalomas (NFAIs). Methods: Multicentre retrospective observational study of patients with NFAIs. ACS was defined as serum...
When non-functioning pituitary adenomas (NFPAs) behave aggressively or recur after first-line surgical treatment, it can be challenging to decide whether and how to escalate therapy. Up to 47% of patients with residual tumor after transsphenoidal sur...
The use of ilities for systems engineering of subsystems and components is investigated. Prior work on ilities has emphasized or restricted their application to system level, non-functional properties. The premise of this work is that ilities can be...
1 December 2010
It is widely recognised that successful online systems are not those that simply fulfil some functional specifications, but rather systems that are developed to also meet a number of non-functional requirements such as security, reliability and trust...
The incidence of pancreatic neuroendocrine tumors (PNETs) is on the rise primarily due to the increasing use of cross-sectional imaging. Most of these incidentally detected lesions are non-functional PNETs with a small proportion of lesions being hor...
17 March 2016
The aim of this study was to assess environmental and hereditary influence on development of pituitary tumors using dermatoglyphic traits. The study was performed on 126 patients of both genders with pituitary tumors (60 non-functional and 66 functio...
Widespread access to low-cost, high computing power allows for increased computerization of everyday life. However, high-performance computers alone cannot meet the demands of systems such as the Internet of Things or multi-agent robotic systems. For...
Comprehensive Geriatric Assessment (CGA) is an integrated clinical process to evaluate frail elderly people in order to create therapy plans that improve their quality and quantity of life. The whole process includes the completion of standardized qu...
Cloud computing has redefined the way in which Spatial Data Infrastructures (SDI) and Web geoportals are designed, managed, and maintained. The cloudification of a geoportal represents the migration of a full-stack geoportal application to an interne...
The correct classification of requirements has become an essential task within software engineering. This study shows a comparison among the text feature extraction techniques, and machine learning algorithms to the problem of requirements engineer c...
Mining activity has been and is one of the most important and indispensable industries for the development of society. Given its role in the provision of raw materials, advancing the development of environmentally friendly mining practices is essenti...
Requirements Engineering (RE) is an important step in the whole software development lifecycle. The problem in RE is to determine the class of the software requirements as functional (FR) and non-functional (NFR). Proper and early identification of t...
This paper presents an approach to GWS (GeospatialWeb Service) discovery through the semantic annotation of WPS (Web Processing Service) service descriptions. The rationale behind this work is that search engines that use appropriate semantic-based s...
With the introduction of 2017 World Health Organization (WHO) classification of endocrine tumors, T-PIT can serve as a complementary tool for identification of silent corticotroph adenomas (SCAs) in some cases if the tumor is not classifiable by pitu...
(1) Background: Pituitary adenomas are benign tumors comprising about 18% of all intracranial tumors, and they often require surgical intervention. Differentiating pituitary tissue from adenoma during surgery is crucial to minimize complications. We...
As key technologies of the fourth industrial revolution, blockchain and digital twins have great potential to enhance collaboration, data sharing, efficiency, and sustainability in the construction industry. Blockchain can improve data integrity and...
This study presents three structures for clearly expressing functional requirements (FRs) and quantitative non-functional requirements (qt-NFRs). Expressing requirements with these structures will allow the understanding of requirements by stakeholde...
Recently, deep learning (DL) has been utilized successfully in different fields, achieving remarkable results. Thus, there is a noticeable focus on DL approaches to automate software engineering (SE) tasks such as maintenance, requirement extraction,...
In the digital era, cybersecurity is integral for preserving national security, digital privacy, and social sustainability. This research emphasizes the role of non-functional equirements (NFRs) in developing secure software systems that enhance soci...
This study aimed to evaluate the optimal extent of lymphadenectomy in patients with nonfunctioning pancreatic neuroendocrine neoplasms. We retrospectively analyzed the clinicopathological data of patients with nonfunctioning pancreatic neuroendocrine...
The presence of involuntary, non-functional jaw muscle activity (NFJMA) has not yet been assessed in patients with disorders of consciousness (DOC), although the presence of bruxism and other forms of movement disorders involving facial muscles is pr...
Background and Objectives: The use of controlled donation after circulatory death (cDCD) donors has significantly increased during the past decades and successfully expanded the donors’ pool. However, warm ischemia may have detrimental effects...
Acromegaly is a rare disease caused by overproduction of growth hormone (GH) by a pituitary adenoma, and consequently increased insulin-like growth factor 1 (IGF-1) concentration. The GH/IGF-1 axis and immune cells interactions are hypothesized to be...
Osteocytic osteolysis/perilacunar remodeling is thought to contribute to the maintenance of mineral homeostasis. Here, we utilized a reversible, adult-onset model of secondary hyperparathyroidism to study femoral bone mineralization density distribut...
Background: Here, we compared the toxicity profiles of contemporary stereotactic radiosurgery (SRS), modern fractionated radiotherapy (FRT), and transsphenoidal surgery used to treat nonfunctioning pituitary macroadenomas. Methods: We included the da...
We present a survey of outcomes on Ulam stability of functional equations in non-Archimedean normed spaces. We focus mainly on functional equations in several variables (including the Cauchy equation, the Jordan–von Neumann equation, the Jensen...
Background and Objectives: Primary adrenal tumors (AT) are a heterogeneous group of neoplasms due to their functional heterogeneity, which results in the diverse clinical presentation of these tumors. The purpose of this study was to examine cross-se...
Cavernous sinus (CS) invasion is an aggressive behavior exhibited by pituitary neuroendocrine tumors (PitNETs). The cause of CS invasion in PitNETs has not been fully elucidated. The tumor immune microenvironment, known to promote aggressive behavior...
Gene therapy is manipulation in/of gene expression in specific cells/tissue to treat diseases. This manipulation is carried out by introducing exogenous nucleic acids, such as DNA or RNA, into the cell. Because of their negative charge and considerab...
The incidence of small and asymptomatic pancreatic neuroendocrine neoplasms (PNENs) has increased due to the widespread use of high-resolution diagnostic imaging in screening programs. Most PNENs are slow-growing indolent neoplasms. However, a local...
Background: This study aimed to summarize the surgical and therapeutic activities of non-functional pancreatic neuroendocrine tumors (NF-PanNETs) and perform survival analyses of a 15-year single-institutional cohort of NF-PanNETs. Methods: In total,...
In China, income disparities between regions continue to widen, especially in rural areas where environmental policies are implemented, where regional development is more underdeveloped and inequality is high. This paper provides an explanation from...
Background/Objectives: Wearable technologies become increasingly important in surveillance of biometric parameters in pregnant women; however, early-stage usability data on wearable form factors specifically designed for pregnant women remain limited...
The development of non-alcoholic beer (NAB) with health benefits, using non-conventional potential probiotic yeasts, offers an interesting alternative to standard NAB brewing strategies. In this study, potential probiotic non-Saccharomyces yeasts Pic...
Background: Non-functional well-differentiated pancreatic neuroendocrine tumors (WD-PanNETs) are complex, heterogeneous malignancies with variable prognosis. Despite guideline recommendations, disparities in access to specialized care may impact surv...
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