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196 Results Found

  • Article
  • Open Access
1 Citations
3,233 Views
18 Pages

13 April 2019

The self-healing nature of concrete has been proved in many studies using various methods. However, the underlying mechanisms and the distinct area of self-healing have not been identified in detail. This study focuses on the limits of the area of se...

  • Article
  • Open Access
7 Citations
2,767 Views
21 Pages

7 March 2022

This paper proposes using neutral axis locations to monitor and quantify the prestress force in post-tensioned precast segmental beams. Strain measurements are used to obtain the neutral axis locations of specific cross-sections of the precast prestr...

  • Article
  • Open Access
19 Citations
6,990 Views
20 Pages

20 February 2017

The neutral axis position (NAP) is a key parameter of a flexural member for structure design and safety evaluation. The accuracy of NAP measurement based on traditional methods does not satisfy the demands of structural performance assessment especia...

  • Article
  • Open Access
8 Citations
2,804 Views
13 Pages

24 October 2019

This article presents an experimental study on the evolution of the neutral axis depth at failure in the critical section with the flexural ductility and plastic rotation capacity of reinforced concrete (RC) lightweight-aggregate concrete (LWAC) beam...

  • Article
  • Open Access
9 Citations
3,069 Views
13 Pages

13 July 2020

Neutral axis passing through the stiffness centroid of a structure is correlated with structural health conditions. Traditional techniques rely on gauge arrays to observe strains at their installation positions, and then locate a neutral axis through...

  • Article
  • Open Access
9 Citations
4,273 Views
21 Pages

1 August 2018

The cross-sectional shape of a linear guideway has been processed before the straightening process. The cross-section features influence not only the position of the neutral axis, but also the applied and residual stresses along the longitudinal dire...

  • Article
  • Open Access
2 Citations
1,215 Views
17 Pages

26 November 2024

The neutral-point potential balance issues in three-level converters have obtained great attention. The popular view thinks that the neutral-point voltage deviation can be suppressed by regulating the injected zero-sequence component, whether via car...

  • Article
  • Open Access
9 Citations
3,713 Views
25 Pages

18 April 2019

It is difficult to detect and evaluate the structural damage in a shield tunnel during operation because many traditional techniques based on the observation of vibrations are limited in daily monitoring in tunnels. Thus, the curvature radius of a st...

  • Article
  • Open Access
1 Citations
1,099 Views
19 Pages

Frequency and Buckling Analysis of FG Beams with Asymmetric Material Distribution and Thermal Effect

  • Xiaokang Du,
  • Liang Yin,
  • Xian Guo,
  • Yuanzhao Chen,
  • Liang Li,
  • Dingguo Zhang and
  • Sijia Chen

1 March 2025

The frequency and buckling characteristics of functional gradient (FG) beams with asymmetric material distribution in the temperature field are analyzed in this paper. Generally, the asymmetrical material distribution of FG beams results in a non-zer...

  • Article
  • Open Access
28 Citations
5,021 Views
31 Pages

3 March 2022

An experimental study was conducted to evaluate the ductility of reinforced concrete beams longitudinally reinforced with hybrid Fiber Reinforced Polymer (FRP)–steel bars. The specimens were fourteen reinforced concrete beams with and without h...

  • Article
  • Open Access
601 Views
17 Pages

Longitudinal Bending Mechanical Performance of Double-O-Tube (DOT) Shield Tunnel

  • Senyong Wang,
  • Lehua Peng,
  • Yuan Zhang and
  • Rongzhu Liang

19 August 2025

The longitudinal equivalent bending stiffness is a critical parameter for assessing the longitudinal responses of Double-O-Tube (DOT) shield tunnels under adjacent construction activities. Based on a longitudinal equivalent continuous model and the c...

  • Article
  • Open Access
3 Citations
2,602 Views
22 Pages

9 February 2023

In order to reduce the self-weight of RC buildings and increase cost-savings, the seismic performance of rectangular hollow sectioned columns was investigated by experimental and analytical studies. Cyclic loading tests were carried out under compres...

  • Article
  • Open Access
2 Citations
2,303 Views
14 Pages

8 January 2022

The fatigue damage behavior of bone has attracted significant attention in both the mechanical and orthopedic fields. However, due to the complex and hierarchical structure of bone, describing the damage process quantitively or qualitatively is still...

  • Proceeding Paper
  • Open Access
3 Citations
2,664 Views
5 Pages

This paper reports the experimental investigation of the durability of screen printed conductor-based strain gauges on four fabrics of different stiffness by examining the change in the electrical resistances during and after bending. Emphasis is pla...

  • Article
  • Open Access
12 Citations
4,352 Views
17 Pages

23 February 2023

Due to the high cost of laboratory testing, many researchers are considering developing methods to predict the behavior of unreinforced and reinforced wood beams. This work aims to create either numerical or analytical models useful for extrapolating...

  • Article
  • Open Access
3 Citations
1,791 Views
17 Pages

28 May 2024

The aim of this paper was to explore the application of multi-channel synchronized dynamic strain gauges in monitoring the neutral axis (N.A.) position of prestressed concrete box girders. The N.A. position has recently been proposed as an indicator...

  • Article
  • Open Access
4 Citations
2,678 Views
22 Pages

16 January 2021

A new type of composite voided slab, the TUBEDECK (TD), which utilizes the structural function of profiled steel decks, has recently been proposed. Previous studies have confirmed that the flexural strength of TD slabs can be calculated based on the...

  • Article
  • Open Access
824 Views
16 Pages

3 September 2025

This study addresses the performance optimization of piezoelectric cantilever beam energy harvesters by proposing a design method based on surface arrayed groove modulation. Through systematic investigation of the effects of single grooves (upper sur...

  • Article
  • Open Access
22 Citations
3,857 Views
29 Pages

20 January 2020

Many studies on cracked rotors developed crack breathing models that assume that the neutral axis of bending always remains horizontal for simplification. These models may generate significant discrepancies and thus there is a need to develop more so...

  • Article
  • Open Access
2 Citations
2,371 Views
12 Pages

Forgivingness of an Anteromedially Positioned Small Locked Plate for High Tibial Osteotomy in Case of Overcorrection and Lateral Hinge Fracture

  • Sabrina Böhle,
  • Lars Bischoff,
  • Kristin Ehrenmann,
  • Frank Layher,
  • Klaus Sander,
  • Georg Matziolis and
  • Stefan Pietsch

19 August 2022

High tibial osteotomy (HTO) represents a sensible treatment option for patients with moderate unicondylar osteoarthritis of the knee and extraarticular malalignment. The possibility of a continuously variable correction setting and a surgical approac...

  • Article
  • Open Access
9 Citations
4,116 Views
23 Pages

4 December 2020

This study examined the hull girder strength of intact and damaged ships by adopting the incremental-iterative method for progressive collapse analysis, which was extended to the general case of the unsymmetrical bending of beams with an arbitrary cr...

  • Article
  • Open Access
6 Citations
3,306 Views
20 Pages

22 September 2023

The conventional methods used to analyze the shear lag effect in simply supported box girders assume that the neutral axis of the section coincides with the centroid, which does not strictly satisfy the axial equilibrium condition. To address this pr...

  • Communication
  • Open Access
4 Citations
1,882 Views
7 Pages

Detecting Wandering Intermediate-Mass Black Holes with AXIS in the Milky Way and Local Massive Galaxies

  • Fabio Pacucci,
  • Bryan Seepaul,
  • Yueying Ni,
  • Nico Cappelluti and
  • Adi Foord

This white paper explores the detectability of intermediate-mass black holes (IMBHs) wandering in the Milky Way (MW) and massive local galaxies, with a particular emphasis on the role of AXIS. IMBHs, ranging within 103−6M⊙, are commonly f...

  • Article
  • Open Access
6 Citations
3,299 Views
23 Pages

14 February 2020

The ultimate limit state function is one of the premises for the assessment of structure strength and the safety of ships under severe conditions. In order to study the residual strength of damaged ships under the combined load of vertical and horizo...

  • Article
  • Open Access
6 Citations
2,518 Views
16 Pages

Optimal Area for a Rectangular Isolated Footing with an Eccentric Column and Partial Ground Compression

  • Victor Manuel Moreno-Landeros,
  • Arnulfo Luévanos-Rojas,
  • Griselda Santiago-Hurtado,
  • Luis Daimir López-León and
  • Eyran Roberto Diaz-Gurrola

24 July 2024

This manuscript aims to present a novel model to find the optimal area of a rectangular isolated footing with an eccentric column, taking into account that the footing is partially supported; that is, one part of the contact surface is compressed and...

  • Communication
  • Open Access
1 Citations
5,250 Views
4 Pages

The purpose of this study was to assess changes in the thickness of the retrocalcaneal bursa (RB) with respect to the ankle position with or without flexor hallucis longus (FHL) contraction. Forty feet of 20 female volunteers were examined. RB was so...

  • Article
  • Open Access
1,867 Views
12 Pages

12 December 2022

The spectral luminescent properties of dipyrromethenates halogenated with bromine on both ends of the long axis and coordinated using boron fluoride, zinc, or cadmium in neutral ethanol and acidified with hydrochloric acid solutions were studied. The...

  • Article
  • Open Access
6 Citations
2,467 Views
18 Pages

Predicted and Experimental Bending Behaviour of Glulam Bonded by RPF Adhesive

  • Tomáš Kytka,
  • Miroslav Gašparík,
  • Lukáš Sahula,
  • David Novák,
  • Elham Karami,
  • Sumanta Das and
  • Martin Sviták

21 January 2024

In this study, alder, spruce, and beech woods were used for homogeneous symmetric, inhomogeneous symmetric (combined) and inhomogeneous non-symmetric glued laminated timber (glulam) beams glued with resorcinol phenol formaldehyde (RPF) adhesive. The...

  • Article
  • Open Access
1 Citations
2,065 Views
8 Pages

Inherent Bias in ROSA® Zimmer Biomet Pre-Op Planning Using 2D to 3D X-Atlas® Coronal Knee Axis Measurement

  • Michał A. Duchniewicz,
  • Aly Shaaban,
  • Manuel Müller,
  • Philip M. Anderson,
  • Lars Goebel,
  • Patrick Orth,
  • Milan A. Wolf,
  • Felix Bachelier,
  • Stefan Landgraeber and
  • Philipp Winter

3 March 2025

Background: Robotic assistance is considered capable of improving precision and outcomes of total knee replacement. We assessed the inherent biases, pre-procedural planning accuracy using 2D to 3D X-Atlas®, and final knee axis outcomes of the ROS...

  • Article
  • Open Access
11 Citations
3,377 Views
17 Pages

Most studies on the ossification of the posterior longitudinal ligament (OPLL) using the finite element method were conducted in the neutral state, and the resulting decompression was judged to be good. As these studies do not reflect the actual beha...

  • Article
  • Open Access
587 Views
21 Pages

Development of Formulas Predicting Bending Moments of Elastic–Plastic and Bi-Modular-Layered Particleboards

  • Yan Wang,
  • Samet Demirel,
  • Wengang Hu,
  • Franklin Quin,
  • Jilei Zhang,
  • Shunyao Sun and
  • Xiaohong Yu

12 August 2025

Four mechanical models were proposed to derive formulas predicting the bending moment capacities of layered particleboard under simply supported center-loading. Experimental validation confirmed these models are effective tools for describing the ben...

  • Article
  • Open Access
2 Citations
5,010 Views
11 Pages

A structural beam which is subjected to shear forces acting perpendicularly to its longitudinal axis will experience longitudinal and transverse shear stresses. In beams where failure in the transverse direction is plausible, it is desirable to maint...

  • Article
  • Open Access
2 Citations
6,000 Views
15 Pages

A New, Adaptable, Optical High-Resolution 3-Axis Sensor

  • Niels Buchhold and
  • Christian Baumgartner

27 January 2017

This article presents a new optical, multi-functional, high-resolution 3-axis sensor which serves to navigate and can, for example, replace standard joysticks in medical devices such as electric wheelchairs, surgical robots or medical diagnosis devic...

  • Brief Report
  • Open Access
9 Citations
3,017 Views
14 Pages

IGFBP7 Fuels the Glycolytic Metabolism in B-Cell Precursor Acute Lymphoblastic Leukemia by Sustaining Activation of the IGF1R–Akt–GLUT1 Axis

  • Leonardo Luís Artico,
  • Juliana Silveira Ruas,
  • José Ricardo Teixeira Júnior,
  • Natacha Azussa Migita,
  • Gustavo Seguchi,
  • Xinghua Shi,
  • Silvia Regina Brandalise,
  • Roger Frigério Castilho and
  • José Andrés Yunes

Increased glycolytic metabolism plays an important role in B-cell precursor Acute Lymphoblastic Leukemia (BCP-ALL). We previously showed that IGFBP7 exerts mitogenic and prosuvival effects in ALL by promoting IGF1 receptor (IGF1R) permanence on the c...

  • Article
  • Open Access
3 Citations
2,177 Views
29 Pages

Effect of Atmospheric Stability on Meandering and Wake Characteristics in Wind Turbine Fluid Dynamics

  • Bendik Peter Løvøy Alvestad,
  • Leon Fevang-Gunn,
  • Balram Panjwani and
  • Tania Kalogiannidis Bracchi

8 September 2024

This study investigates the impact of atmospheric stability on wind turbine flow dynamics, focusing on wake deflection and meandering. Using the high-fidelity large-eddy simulation coupled with the Actuator Line model, we explore three stability cond...

  • Article
  • Open Access
21 Citations
4,208 Views
9 Pages

Effect of Coronal Alignment on 10-Year Survivorship of a Single Contemporary Total Knee Arthroplasty

  • Meagan E. Tibbo,
  • Afton K. Limberg,
  • Kevin I. Perry,
  • Mark W. Pagnano,
  • Michael J. Stuart,
  • Arlen D. Hanssen and
  • Matthew P. Abdel

4 January 2021

Debate remains regarding the utility of mechanical axis alignment as a predictor of durability after total knee arthroplasty (TKA). Our study aimed to assess the effects of coronal alignment on implant durability, clinical outcomes, and radiographic...

  • Article
  • Open Access
10 Citations
2,966 Views
15 Pages

24 December 2020

Hydroxyapatite coatings have been widely used to improve the corrosion resistance of biodegradable magnesium alloys. In this paper, in order to manufacture the ideal hydroxyapatite (HA) coating on the ZK60 magnesium substrate by hydrothermal method,...

  • Article
  • Open Access
2 Citations
1,860 Views
20 Pages

Investigation on Flexural Fracture Behaviour of Bolted Spherical Joints with Crack Propagation in Screw Threads

  • Qinghong Shi,
  • Wenfeng Zhou,
  • Xiang You,
  • Yinggai Liu,
  • Zhiyu Wang and
  • Qunyi Huang

17 May 2023

Bolted spherical joints, due to their prominent merits in installation, have been widely used in modern spatial structures. Despite significant research, there is a lack of understanding of their flexural fracture behaviour, which is important for th...

  • Feature Paper
  • Article
  • Open Access
51 Citations
11,930 Views
15 Pages

Ionoprinted Multi-Responsive Hydrogel Actuators

  • Daniel Morales,
  • Igor Podolsky,
  • Russell W. Mailen,
  • Timothy Shay,
  • Michael D. Dickey and
  • Orlin D. Velev

We report multi-responsive and double-folding bilayer hydrogel sheet actuators, whose directional bending response is tuned by modulating the solvent quality and temperature and where locally crosslinked regions, induced by ionoprinting, enable the a...

  • Article
  • Open Access
4 Citations
4,333 Views
18 Pages

Structure-Guided Creation of an Anti-HA Stalk Antibody F11 Derivative That Neutralizes Both F11-Sensitive and -Resistant Influenza A(H1N1)pdm09 Viruses

  • Osamu Kotani,
  • Yasushi Suzuki,
  • Shinji Saito,
  • Akira Ainai,
  • Akira Ueno,
  • Takuya Hemmi,
  • Kaori Sano,
  • Koshiro Tabata,
  • Masaru Yokoyama and
  • Hironori Sato
  • + 2 authors

31 August 2021

The stalk domain of influenza virus envelope glycoprotein hemagglutinin (HA) constitutes the axis connecting the head and transmembrane domains, and plays pivotal roles in conformational rearrangements of HA for virus infection. Here we characterized...

  • Article
  • Open Access
2,629 Views
16 Pages

5 July 2022

This paper proposes and researches a novel cylinder-type FOWT using a neutrally buoyant double-layer torus structure with annular flow; its oscillatory motion in severe sea conditions is controlled by a spinning top device designed as a neutrally buo...

  • Article
  • Open Access
5 Citations
4,301 Views
18 Pages

CoV-RBD121-NP Vaccine Candidate Protects against Symptomatic Disease following SARS-CoV-2 Challenge in K18-hACE2 Mice and Induces Protective Responses That Prevent COVID-19-Associated Immunopathology

  • Jennifer K. DeMarco,
  • Joshua M. Royal,
  • William E. Severson,
  • Jon D. Gabbard,
  • Steve Hume,
  • Josh Morton,
  • Kelsi Swope,
  • Carrie A. Simpson,
  • John W. Shepherd and
  • Gregory P. Pogue
  • + 2 authors

17 November 2021

We developed a SARS-CoV-2 vaccine candidate (CoV-RBD121-NP) comprised of a tobacco mosaic virus-like nanoparticle conjugated to the receptor-binding domain of the spike glycoprotein of SARS-CoV-2 fused to a human IgG1 Fc domain. CoV-RBD121-NP elicits...

  • Article
  • Open Access
1,319 Views
24 Pages

The main objective of this research is to investigate the impact of the tendon profile layout on the shear strength of unbonded post-tensioned prestressed concrete bridge I-girders. This study involves an experimental investigation where ten unbonded...

  • Article
  • Open Access
1 Citations
1,094 Views
19 Pages

PTEN/PKM2/ERα-Driven Glyoxalase 1 Overexpression Sustains PC3 Prostate Cancer Cell Growth Through MG-H1/RAGE Pathway Desensitization Leading to H2O2-Dependent KRIT1 Downregulation

  • Dominga Manfredelli,
  • Camilla Torcoli,
  • Marilena Pariano,
  • Guido Bellezza,
  • Tiziano Baroni,
  • Vincenzo N. Talesa,
  • Angelo Sidoni and
  • Cinzia Antognelli

15 September 2025

Glyoxalase 1 (Glo1) functions as a catalyst that neutralizes methylglyoxal (MG), a highly reactive glycating agent predominantly produced during glycolysis—a metabolic pathway upregulated in cancer cells. MG primarily reacts with the amino grou...

  • Article
  • Open Access
706 Views
21 Pages

Pressure Force in the Upper Ankle Joint

  • Jacek Marek Dygut and
  • Monika Weronika Piwowar

20 October 2025

Background: This paper concerns the study of forces acting on the upper ankle joint of a human in static and quasi-dynamic positions. This paper aimed to determine the pressure forces on the axis of the upper ankle joint in the position of the body t...

  • Article
  • Open Access
21 Citations
4,450 Views
11 Pages

Semaphorin4A-Plexin D1 Axis Induces Th2 and Th17 While Represses Th1 Skewing in an Autocrine Manner

  • Tiago Carvalheiro,
  • Carlos Rafael-Vidal,
  • Beatriz Malvar-Fernandez,
  • Ana P. Lopes,
  • Jose M. Pego-Reigosa,
  • Timothy R. D. J. Radstake and
  • Samuel Garcia

22 September 2020

Semaphorin (Sema)4A is a transmembrane glycoprotein that is elevated in several autoimmune diseases such as systemic sclerosis, rheumatoid arthritis and multiple sclerosis. Sema4A has a key role in the regulation of Thelper Th1 and Th2 differentiatio...

  • Article
  • Open Access
16 Citations
3,372 Views
18 Pages

4 November 2020

Metastasis and recurrence are the main causes of lung adenocarcinoma patients’ death. Lymphatic metastasis is the main way of non-small cell lung cancer (NSCLC) metastasis. C-C chemokine receptor type 7 (CCR7) overexpression has been demonstrat...

  • Article
  • Open Access
479 Views
16 Pages

Activation of TSLP–IL-9 Axis Hinders the Antifibrotic Effect of ST2 Deficiency in Pulmonary Fibrosis

  • Sergei P. Atamas,
  • Virginia Lockatell,
  • Zhongcheng Mei,
  • Mohan E. Tulapurkar,
  • Katerina N. Lugkey,
  • Alexander Sasha Krupnick and
  • Irina G. Luzina

5 December 2025

Previous studies have suggested that activation of the IL-33/ST2 axis as well as elevated expression of the full-length IL-33 precursor acting in an ST2-independent fashion both contribute to pulmonary fibrosis. The protective effect of genetic ST2 d...

  • Article
  • Open Access
3 Citations
2,915 Views
13 Pages

AB5-Type Toxin as a Pentameric Scaffold in Recombinant Vaccines against the Japanese Encephalitis Virus

  • Jina Ahn,
  • Ji Eun Yu,
  • Hanna Kim,
  • Jemin Sung,
  • Gyoonhee Han,
  • Myung Hyun Sohn and
  • Baik-Lin Seong

29 June 2023

Japanese encephalitis virus (JEV) is an enveloped icosahedral capsid virus with a prime neutralizing epitope present in E protein domain III (EDIII). E dimers are rearranged into a five-fold symmetry of icosahedrons. Cholera toxin B (CTB) and heat-la...

  • Article
  • Open Access
4 Citations
4,003 Views
15 Pages

Equipment and Technology for Combined Ion–Plasma Strengthening of Cutting Tools

  • Sergey N. Grigoriev,
  • Alexander S. Metel,
  • Yury A. Melnik and
  • Marina A. Volosova

9 November 2018

A combined strengthening of cutting tools for finishing has been carried out in glow discharge plasma filling a process vacuum chamber. At the first stage, reamers rotating around the axis distanced from the magnetron targets at 8 cm were bombarded b...

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