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13 pages, 822 KiB  
Article
Analysis of Sequential Pneumococcal Vaccination Coverage in the Elderly Resident Population of the Viterbo Local Health Authority from 2018 to 2023
by Andrea Bongiovanni, Giulia Santolini, Francesco Vairo, Francesco Corea, Silvia Aquilani and Chiara de Waure
Vaccines 2025, 13(8), 807; https://doi.org/10.3390/vaccines13080807 - 30 Jul 2025
Viewed by 282
Abstract
Background: Pneumococcal disease is a significant health burden, particularly among older adults and individuals with chronic conditions. Sequential pneumococcal vaccination (PCV13 followed by PPSV23) has been recommended in Italy since 2017 for its demonstrated efficacy, safety, and cost-effectiveness in preventing invasive pneumococcal disease [...] Read more.
Background: Pneumococcal disease is a significant health burden, particularly among older adults and individuals with chronic conditions. Sequential pneumococcal vaccination (PCV13 followed by PPSV23) has been recommended in Italy since 2017 for its demonstrated efficacy, safety, and cost-effectiveness in preventing invasive pneumococcal disease (IPD). Nevertheless, limited data are available on the sequential pneumococcal vaccination coverage in Italy. This study aimed to evaluate the coverage and trends of sequential pneumococcal vaccination among individuals who turned 65 years old within the Viterbo Local Health Authority between 2018 and 2023. Methods: A retrospective cohort study was conducted using data from the Regional Vaccination Registry (AVR), a comprehensive digital vaccination dataset. Vaccination coverage was calculated based on individuals completing the sequential pneumococcal vaccination within two years after turning 65 years old. Trends as well as subgroup variations based on sex, citizenship, district of residence, and municipality size were analyzed. Results: Among 27,657 individuals who turned 65 years of age during the study period, only 2.32% completed the sequential pneumococcal vaccination. Coverage increased steadily from 2018 (0.60%) to a peak in 2020 (3.27%), followed by a plateau and a decline in 2023 (2.53%). Coverage varied across demographic and geographic subgroups: females (2.58%) had higher coverage than males (2.04%), Italian citizens (2.45%) exceeded foreign residents (0.64%), and residents in District C (3.03%) led over District A (1.08%). Smaller municipalities (≤10,000 inhabitants) showed higher coverage (2.52%) than larger ones (1.98%). Conclusions: Adherence to sequential pneumococcal vaccination has been very low throughout the considered study period. This is highly relevant information to consider in the view of new available pneumococcal vaccines for immunization of the elderly. Furthermore, geographic and demographic differences highlight the need for targeted public health interventions. Full article
(This article belongs to the Special Issue Vaccines and Vaccine Preventable Diseases)
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15 pages, 642 KiB  
Article
MIH and Cavities as Markers of Oral Health Inequality in Children from Southwest Andalusia (Spain)
by Leidy Bech Barcaz, David Ribas-Pérez, Paloma Villalva Hernandez-Franch, Luis El Khoury-Moreno, Julio Torrejón-Martínez and Antonio Castaño-Séiquer
Dent. J. 2025, 13(8), 345; https://doi.org/10.3390/dj13080345 - 26 Jul 2025
Viewed by 274
Abstract
Introduction: Dental caries and molar–incisor hypomineralisation (MIH) are prevalent conditions affecting children’s oral health, with functional, aesthetic, and psychosocial implications. In Spain, previous studies have highlighted geographic and sociodemographic disparities in their distribution, particularly among rural and migrant populations. Objective: To characterise oral [...] Read more.
Introduction: Dental caries and molar–incisor hypomineralisation (MIH) are prevalent conditions affecting children’s oral health, with functional, aesthetic, and psychosocial implications. In Spain, previous studies have highlighted geographic and sociodemographic disparities in their distribution, particularly among rural and migrant populations. Objective: To characterise oral health status, in terms of caries and MIH, among 6–7-year-old children from the towns of Palos de la Frontera, Mazagón, and San Bartolomé. Methods: A cross-sectional study was conducted involving 229 children recruited from public primary schools. Sociodemographic, anthropometric, and behavioural data were collected through clinical examination and interview. Statistical analysis included univariate and multivariate logistic regression. The study protocol was approved by the Ethics Committee of Huelva. Results: The prevalence of caries (DMFT ≥ 1) was 53.3%, with mean DMFT and dft indices of 1.78 and 0.31, respectively. MIH affected 32.8% of the cohort, with a predominance in the first permanent molars (teeth 36 and 26). Multivariate analysis identified independent predictors of caries: African (OR = 7.47; 95% CI: 2.84–23.8) and European (OR = 4.56; 95% CI: 1.26–22.3) parental origin, poor oral hygiene (OR = 3.07; 95% CI: 1.60–6.03), and the presence of MIH (OR = 3.20; 95% CI: 1.64–6.42). The municipality of San Bartolomé was associated with a higher risk of MIH (OR = 2.90; 95% CI: 1.21–7.45). Conclusions: The high prevalence of caries and MIH in the Condado-Campiña district, exceeding national averages, reflects oral health inequities linked to social determinants (migrant origin, locality) and clinical factors (MIH, oral hygiene). Targeted preventive interventions are urgently needed in high-risk populations, including culturally tailored education and policies ensuring equitable access to dental care services. Full article
(This article belongs to the Topic Preventive Dentistry and Public Health)
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24 pages, 3509 KiB  
Article
Water: The Central Theme of the Proposed Sonora Estuarine Biocultural Corridor of Northwestern Mexico
by Diana Luque-Agraz, Martha A. Flores-Cuamea, Alessia Kachadourian-Marras, Lara Cornejo-Denman and Arthur D. Murphy
Water 2025, 17(15), 2227; https://doi.org/10.3390/w17152227 - 26 Jul 2025
Viewed by 384
Abstract
The Sonora Estuarine Biocultural Corridor (CBES) is made up of six coastal wetlands with mangrove forest, internationally certified as Ramsar Sites. Four are part of indigenous territories whose inhabitants have serious development lags and low water security. Five are within one or more [...] Read more.
The Sonora Estuarine Biocultural Corridor (CBES) is made up of six coastal wetlands with mangrove forest, internationally certified as Ramsar Sites. Four are part of indigenous territories whose inhabitants have serious development lags and low water security. Five are within one or more of six irrigation districts of national relevance. The objective is to learn about the socio-environmental problems of the CBES, focused on the issue of water, as well as community proposals for solutions. Intercultural, mixed methodology approach. Prospecting visits were carried out in the six estuaries of the CBES, and 84 semi-structured interviews were conducted with experts from all social sectors who know the problems of the CBES in three (out of six) estuaries associated with indigenous territories. The main problem is centered on the issue of water: they receive contaminated water from agroindustry, aquaculture, and the municipal service; the fresh water of the rivers is almost nil, rainfall has decreased while the heat increases, and marine and terrestrial biodiversity decreases. This affects the food and economic security of the local population and generates conflicts between the different productive activities. A multisectoral organization that integrates the six estuaries would improve community wellbeing and, in turn, climate resilience. Full article
(This article belongs to the Section Water Resources Management, Policy and Governance)
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49 pages, 4131 KiB  
Review
Municipal Solid Waste Gasification: Technologies, Process Parameters, and Sustainable Valorization of By-Products in a Circular Economy
by Nicoleta Ungureanu, Nicolae-Valentin Vlăduț, Sorin-Ștefan Biriș, Mariana Ionescu and Neluș-Evelin Gheorghiță
Sustainability 2025, 17(15), 6704; https://doi.org/10.3390/su17156704 - 23 Jul 2025
Viewed by 417
Abstract
Gasification of municipal solid waste and other biogenic residues (e.g., biomass and biowaste) is increasingly recognized as a promising thermochemical pathway for converting non-recyclable fractions into valuable energy carriers, with applications in electricity generation, district heating, hydrogen production, and synthetic fuels. This paper [...] Read more.
Gasification of municipal solid waste and other biogenic residues (e.g., biomass and biowaste) is increasingly recognized as a promising thermochemical pathway for converting non-recyclable fractions into valuable energy carriers, with applications in electricity generation, district heating, hydrogen production, and synthetic fuels. This paper provides a comprehensive analysis of major gasification technologies, including fixed bed, fluidized bed, entrained flow, plasma, supercritical water, microwave-assisted, high-temperature steam, and rotary kiln systems. Key aspects such as feedstock compatibility, operating parameters, technology readiness level, and integration within circular economy frameworks are critically evaluated. A comparative assessment of incineration and pyrolysis highlights the environmental and energetic advantages of gasification. The valorization pathways for main product (syngas) and by-products (syngas, ash, tar, and biochar) are also explored, emphasizing their reuse in environmental, agricultural, and industrial applications. Despite progress, large-scale adoption in Europe is constrained by economic, legislative, and technical barriers. Future research should prioritize scaling emerging systems, optimizing by-product recovery, and improving integration with carbon capture and circular energy infrastructures. Supported by recent European policy frameworks, gasification is positioned to play a key role in sustainable waste-to-energy strategies, biomass valorization, and the transition to a low-emission economy. Full article
(This article belongs to the Special Issue Sustainable Waste Process Engineering and Biomass Valorization)
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15 pages, 12820 KiB  
Article
MCDM-Based Analysis of Site Suitability for Renewable Energy Community Projects in the Gargano District
by Rosa Agliata, Filippo Busato and Andrea Presciutti
Sustainability 2025, 17(14), 6376; https://doi.org/10.3390/su17146376 - 11 Jul 2025
Viewed by 573
Abstract
The increasing urgency of the energy transition, particularly in ecologically sensitive regions, demands spatially informed planning tools to guide renewable energy development. This study presents a Multi-Criteria Decision-Making (MCDM) approach to assess the suitability of the Gargano district in southern Italy for the [...] Read more.
The increasing urgency of the energy transition, particularly in ecologically sensitive regions, demands spatially informed planning tools to guide renewable energy development. This study presents a Multi-Criteria Decision-Making (MCDM) approach to assess the suitability of the Gargano district in southern Italy for the implementation of Renewable Energy Communities. The analysis combines expert-based weighting and the Weighted Linear Combination method to evaluate seven key criteria grouped into environmental, socioeconomic, and technical dimensions. The resulting suitability scores, calculated at the municipal scale, highlight spatial disparities across the district, revealing that areas with the highest potential for Renewable Energy Community (REC) deployment are largely situated at the boundaries of the Gargano National Park. These zones benefit from stronger infrastructure, higher energy demand, and fewer environmental constraints, particularly with regard to wind energy initiatives. Conversely, municipalities within the park exhibit lower suitability, constrained by strict landscape regulations and lower population density. The findings provide valuable insights for regional planners and policymakers, supporting the adoption of targeted, environmentally compatible strategies for the advancement of citizen-led renewable energy initiatives in complex territorial contexts. Full article
(This article belongs to the Section Energy Sustainability)
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21 pages, 1524 KiB  
Article
An Analysis of Implementation Constraints of Spatial Planning Tools for Disaster Risk Reduction in Mopani’s Informal Settlements, South Africa
by Juliet Akola and Mvuyana Bongekile Yvonne Charlotte
Sustainability 2025, 17(13), 6075; https://doi.org/10.3390/su17136075 - 2 Jul 2025
Viewed by 366
Abstract
Urbanization is rapidly transforming cities, especially in the Global South, with Sub-Saharan Africa expected to see the fastest growth in the next 30 years. In South Africa’s Mopani District, this urban expansion has led to the growth of informal settlements, increasing disaster risks [...] Read more.
Urbanization is rapidly transforming cities, especially in the Global South, with Sub-Saharan Africa expected to see the fastest growth in the next 30 years. In South Africa’s Mopani District, this urban expansion has led to the growth of informal settlements, increasing disaster risks related to water, health, and fire. This study focuses on Giyani Local Municipality, examining disaster risks in its informal settlements and the factors influencing the implementation of spatial planning tools. Using a SWOT analysis combined with the Analytical Hierarchy Process (AHP), the study found that while the municipality has strong land use and disaster management policies, poor enforcement, lack of integration, and weak governance limit their effectiveness. Opportunities for improvement include securing grants from the National Government and Disaster Management Centre to support disaster risk reduction (DRR) initiatives. However, challenges such as land shortages and ecological degradation threaten sustainable planning. The findings provide important insights for policymakers, urban planners, and disaster management professionals. The SWOT-AHP approach helps in prioritizing resource allocation, identifying risk trends, and focusing on key areas for mitigation. Overall, the study supports efforts to enhance resilience and promote sustainable urban development in informal settlements through better spatial planning. Full article
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24 pages, 4066 KiB  
Article
Analysing the Market Value of Land Accommodating Logistics Facilities in the City of Cape Town Municipality, South Africa
by Masilonyane Mokhele
Sustainability 2025, 17(13), 5776; https://doi.org/10.3390/su17135776 - 23 Jun 2025
Viewed by 416
Abstract
The world is characterised by the growing volumes and flow of goods, which, amid benefits to economic development, result in negative externalities affecting the sustainability of cities. Although numerous studies have analysed the locational patterns of logistics facilities in cities, further research is [...] Read more.
The world is characterised by the growing volumes and flow of goods, which, amid benefits to economic development, result in negative externalities affecting the sustainability of cities. Although numerous studies have analysed the locational patterns of logistics facilities in cities, further research is required to examine their real estate patterns and trends. The aim of the paper is, therefore, to analyse the value of land accommodating logistics facilities in the City of Cape Town municipality, South Africa. Given the lack of dedicated geo-spatial data, logistics firms were searched on Google Maps, utilising a combination of aerial photography and street view imagery. Three main attributes of land parcels hosting logistics facilities were thereafter captured from the municipal cadastral information: property extent, street address, and property number. The latter two were used to extract the 2018 and 2022 property market values from the valuation rolls on the municipal website, followed by statistical, spatial, and geographically weighted regression (GWR) analyses. Zones near the central business district and seaport, as well as areas with prime road-based accessibility, had high market values, while those near the railway stations did not stand out. However, GWR yielded weak relationships between market values and the locational variables analysed, arguably showing a disconnect between spatial planning and logistics planning. Towards augmenting sustainable logistics, it is recommended that relevant stakeholders strategically integrate logistics into spatial planning, and particularly revitalise freight rail to attract investment to logistics hubs with direct railway access. Full article
(This article belongs to the Special Issue Sustainable Transport and Land Use for a Sustainable Future)
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23 pages, 4156 KiB  
Article
Spatiotemporal Drivers of Urban Vegetation Carbon Sequestration in the Yangtze River Delta Urban Agglomeration: A Remote Sensing-Based GWR-RF-SEM Framework Analysis
by Weibo Ma, Yueming Zhu, Depin Ou, Yicong Chen, Yamei Shao, Nannan Wang, Nan Wang and Haidong Li
Remote Sens. 2025, 17(12), 2110; https://doi.org/10.3390/rs17122110 - 19 Jun 2025
Viewed by 641
Abstract
Vegetation carbon sequestration (CS) is critical for mitigating climate change in urban agglomerations, yet its driving mechanisms remain poorly understood in rapidly urbanizing regions. This study introduces an integrated attribution and influence analysis framework, GWR-RF-SEM, to quantitatively assess the driving forces, mechanisms, and [...] Read more.
Vegetation carbon sequestration (CS) is critical for mitigating climate change in urban agglomerations, yet its driving mechanisms remain poorly understood in rapidly urbanizing regions. This study introduces an integrated attribution and influence analysis framework, GWR-RF-SEM, to quantitatively assess the driving forces, mechanisms, and pathways of CS using multi-source remote sensing data at the county scale within the Yangtze River Delta Urban Agglomeration (YRDUA), China, from 2001 to 2020. Our results reveal an overall increase in CS across 70.14% districts in the YRDUA, with municipal districts exhibiting significantly lower CS compared to the outside districts. Photosynthesis and human activities emerged as the dominant drivers, collectively accounting for 73.1% of CS variation, significantly surpassing the influence of climate factors. Although most factors influenced urban vegetation CS either directly or indirectly, photosynthesis, afforestation, and urban green space structure were identified as the primary direct drivers of CS enhancement in both districts. Notably, we found significant spatial heterogeneity in CS drivers between municipal districts and the outside districts, highlighting the need for targeted strategies to enhance CS efficiency. These findings advance our understanding of urban vegetation CS mechanisms, providing essential support for the enhancement of nature-based solutions depending on ecosystem services under urbanization and climate change. Full article
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27 pages, 705 KiB  
Article
Modelling Municipal Cost Inefficiencies in the Frances Baard District of South Africa and Their Impact on Service Delivery
by Brian Tavonga Mazorodze
Adm. Sci. 2025, 15(6), 229; https://doi.org/10.3390/admsci15060229 - 13 Jun 2025
Cited by 1 | Viewed by 583
Abstract
Section 195(b) of South Africa’s Constitution calls for the efficient use of resources in public administration, while the White Paper on Local Government similarly emphasizes the efficient provision of basic services such as refuse collection and water. Despite these policy commitments, South African [...] Read more.
Section 195(b) of South Africa’s Constitution calls for the efficient use of resources in public administration, while the White Paper on Local Government similarly emphasizes the efficient provision of basic services such as refuse collection and water. Despite these policy commitments, South African municipalities continue to be characterized by financial mismanagement and poor service delivery. In light of the limited empirical evidence on this issue, this study pursues two objectives. First, it estimates the levels of cost inefficiency in four local municipalities within the Frances Baard District from 2006 to 2023. Second, it determines how cost inefficiencies affect service delivery, focusing on water and refuse collection. Using a stochastic frontier analysis, several key results are confirmed. First, on average, the four municipalities are found to have spent 17.23% above the minimum cost required to deliver existing services. Second, service delivery is found to have been 23% lower than its potential. Third, operating costs and contracted services are found to have been key drivers of wasteful expenditure. Lastly, cost inefficiencies are found to have culminated in poor service delivery. Against this background, municipalities are urged to consider cutting non-essential operational spending such as entertainment and travel allowances, coupled with improved accountability on contracted services. Full article
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38 pages, 6637 KiB  
Article
Socio-Spatial Bridging Through Walkability: A GIS and Mixed-Methods Analysis in Amman, Jordan
by Majd Al-Homoud and Sara Al-Zghoul
Buildings 2025, 15(12), 1999; https://doi.org/10.3390/buildings15121999 - 10 Jun 2025
Viewed by 544
Abstract
Decades of migration and refugee influxes have driven Amman’s rapid urban growth, yet newer neighborhoods increasingly grapple with fragmented social cohesion. This study examines whether walkable design can strengthen community bonds, focusing on Deir Ghbar, a car-centric district in West Amman. Using GIS [...] Read more.
Decades of migration and refugee influxes have driven Amman’s rapid urban growth, yet newer neighborhoods increasingly grapple with fragmented social cohesion. This study examines whether walkable design can strengthen community bonds, focusing on Deir Ghbar, a car-centric district in West Amman. Using GIS and mixed-methods analysis, we assess how walkability metrics (residential density, street connectivity, land-use mix, and retail density) correlate with sense of community. The results reveal that street connectivity and residential density enhance social cohesion, while land-use mix exhibits no significant effect. High-density, compact neighborhoods foster neighborly interactions, but major roads disrupt these connections. A critical mismatch emerges between quantitative land-use metrics and resident experiences, highlighting the need to integrate spatial data with community insights. Amman’s zoning policies, particularly the stark contrast between affluent low-density Zones A/B and underserved high-density Zones C/D, perpetuate socio-spatial segregation—a central critique of this study. We urge the Greater Amman Municipality’s 2025 Master Plan to prioritize mixed-density zoning, pedestrian retrofits (e.g., traffic calming and sidewalk upgrades), and equitable access to amenities. This study provides a replicable GIS and survey-based framework to address urban socio-spatial divides, aligning with SDG 11 for inclusive cities. It advocates for mixed-density zoning and pedestrian-first interventions in Amman’s Master Plan. By integrating a GIS with social surveys, this study offers a replicable model for addressing socio-spatial divides in cities facing displacement and inequality. Full article
(This article belongs to the Section Architectural Design, Urban Science, and Real Estate)
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43 pages, 14882 KiB  
Article
Planning for Cultural Connectivity: Modeling and Strategic Use of Architectural Heritage Corridors in Heilongjiang Province, China
by Lyuhang Feng, Jiawei Sun, Tongtong Zhai, Mingrui Miao and Guanchao Yu
Buildings 2025, 15(12), 1970; https://doi.org/10.3390/buildings15121970 - 6 Jun 2025
Viewed by 555
Abstract
This study focuses on the systematic conservation of historical architectural heritage in Heilongjiang Province, particularly addressing the challenges of point-based protection and spatial fragmentation. It explores the construction of a connected and conductive heritage corridor network, using historical building clusters across the province [...] Read more.
This study focuses on the systematic conservation of historical architectural heritage in Heilongjiang Province, particularly addressing the challenges of point-based protection and spatial fragmentation. It explores the construction of a connected and conductive heritage corridor network, using historical building clusters across the province as empirical cases. A comprehensive analytical framework is established by integrating the nearest neighbor index, kernel density estimation, minimum cumulative resistance (MCR) model, entropy weighting, circuit theory, and network structure metrics. Kernel density analysis reveals a distinct spatial aggregation pattern, characterized by “one core, multiple zones.” Seven resistance factors—including elevation, slope, land use, road networks, and service accessibility—are constructed, with weights assigned through an entropy-based method to generate an integrated resistance surface and suitability map. Circuit theory is employed to simulate cultural “current” flows, identifying 401 potential corridors at the provincial, municipal, and district levels. A hierarchical station system is further developed based on current density, forming a coordinated structure of primary trunks, secondary branches, and complementary nodes. The corridor network’s connectivity is evaluated using graph-theoretic indices (α, β, and γ), which indicate high levels of closure, structural complexity, and accessibility. The results yield the following key findings: (1) Historical architectural resources in Heilongjiang demonstrate significant coupling with the Chinese Eastern Railway and multi-ethnic cultural corridors, forming a “one horizontal, three vertical” spatial configuration. The horizontal axis (Qiqihar–Harbin–Mudanjiang) aligns with the core cultural route of the railway, while the three vertical axes (Qiqihar–Heihe, Harbin–Heihe, and Mudanjiang–Luobei) correspond to ethnic cultural pathways. This forms a framework of “railway as backbone, ethnicity as wings.” (2) Comparative analysis of corridor paths, railways, and highways reveals structural mismatches in certain regions, including absent high-speed connections along northern trunk lines, insufficient feeder lines in secondary corridors, sparse terminal links, and missing ecological stations near regional boundaries. To address these gaps, a three-tier transportation coordination strategy is recommended: it comprises provincial corridors linked to high-speed rail, municipal corridors aligned with conventional rail, and district corridors connected via highway systems. Key enhancement zones include Yichun–Heihe, Youyi–Hulin, and Hegang–Wuying, where targeted infrastructure upgrades and integrated station hubs are proposed. Based on these findings, this study proposes a comprehensive governance paradigm for heritage corridors that balances multi-level coordination (provincial–municipal–district) with ecological planning. A closed-loop strategy of “identification–analysis–optimization” is developed, featuring tiered collaboration, cultural–ecological synergy, and multi-agent dynamic evaluation. The framework provides a replicable methodology for integrated protection and spatial sustainability of historical architecture in Heilongjiang and other cold-region contexts. Full article
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13 pages, 256 KiB  
Article
“We Report to Traditional Leaders, but Patriarchy Means We Rarely Win the Case”: Gender-Based Violence and Women’s Wellness in Rural South Africa
by Casey Joyce Mabasa, Gudani Goodman Mukoma and Bumani Solomon Manganye
Int. J. Environ. Res. Public Health 2025, 22(6), 887; https://doi.org/10.3390/ijerph22060887 - 31 May 2025
Viewed by 815
Abstract
Background: Gender-based violence has serious health impacts on survivors and is perpetuated by cultural norms, patriarchy, and traditional values. This study explored women’s (survivors) views, attitudes and the impact of gender-based violence on their health in a selected rural village within the Collins [...] Read more.
Background: Gender-based violence has serious health impacts on survivors and is perpetuated by cultural norms, patriarchy, and traditional values. This study explored women’s (survivors) views, attitudes and the impact of gender-based violence on their health in a selected rural village within the Collins Chabane Municipality, Vhembe District, Limpopo Province. Methods: A qualitative descriptive design was used, involving 20 women aged 18 to 59. Semi-structured in-depth interviews were conducted, and data were analysed thematically using ATLAS.ti 8, based on Braun and Clarke’s six-step framework. Ethical considerations were prioritised due to the sensitive nature of the research. Results: The results revealed that women in the Collins Chabane Municipality experience multiple forms of GBV, including physical, sexual, emotional, and financial abuse, which severely impacts their mental and physical health. Additionally, socioeconomic factors like unemployment and financial dependence exacerbate their vulnerability, making it difficult to escape abusive relationships. Conclusions: Cultural norms, patriarchal beliefs, and limited community support intersect to shape women’s experiences and responses to abuse. Full article
20 pages, 2416 KiB  
Article
Examination of Runs of Homozygosity Distribution Patterns and Relevant Candidate Genes of Potential Economic Interest in Russian Goat Breeds Using Whole-Genome Sequencing
by Tatiana E. Deniskova, Arsen V. Dotsev, Olga A. Koshkina, Anastasia D. Solovieva, Nadezhda A. Churbakova, Sergey N. Petrov, Alexey N. Frolov, Stanislav A. Platonov, Alexandra S. Abdelmanova, Maxim A. Vladimirov, Elena A. Gladyr, Igor V. Gusev, Svyatoslav V. Lebedev, Darren K. Griffin, Michael N. Romanov and Natalia A. Zinovieva
Genes 2025, 16(6), 631; https://doi.org/10.3390/genes16060631 - 24 May 2025
Viewed by 579
Abstract
Background/Objectives: Whole-genome sequencing (WGS) data provide valuable information about the genetic architecture of local livestock but have not yet been applied to Russian native goats, in particular, the Orenburg and Karachay breeds. A preliminary search for selection signatures based on single nucleotide polymorphism [...] Read more.
Background/Objectives: Whole-genome sequencing (WGS) data provide valuable information about the genetic architecture of local livestock but have not yet been applied to Russian native goats, in particular, the Orenburg and Karachay breeds. A preliminary search for selection signatures based on single nucleotide polymorphism (SNP) genotype data in these breeds was not informative. Therefore, in this study, we aimed to address runs of homozygosity (ROHs) patterns and find the respective signatures of selection overlapping candidate genes in Orenburg and Karachay goats using the WGS approach. Methods: Paired-end libraries (150 bp reads) were constructed for each animal. Next-generation sequencing was performed using a NovaSeq 6000 sequencer (Illumina, Inc., San Diego, CA, USA), with ~20X genome coverage. ROHs were identified in sliding windows, and ROH segments shared by at least 50% of the samples were considered as ROH islands. Results: ROH islands were identified on chromosomes CHI3, CHI5, CHI7, CHI12, CHI13, and CHI15 in Karachay goats; and CHI3, CHI11, CHI12, CHI15, and CHI16 in Orenburg goats. Shared ROH islands were found on CHI12 (containing the PARP4 and MPHOSPH8 candidate genes) and on CHI15 (harboring STIM1 and RRM1). The Karachay breed had greater ROH length and higher ROH number compared to the Orenburg breed (134.13 Mb and 695 vs. 78.43 Mb and 438, respectively). The genomic inbreeding coefficient (FROH) varied from 0.032 in the Orenburg breed to 0.054 in the Karachay breed. Candidate genes associated with reproduction, milk production, immunity-related traits, embryogenesis, growth, and development were identified in ROH islands in the studied breeds. Conclusions: Here, we present the first attempt of elucidating the ROH landscape and signatures of selection in Russian local goat breeds using WGS analysis. Our findings will pave the way for further insights into the genetic mechanisms underlying adaption and economically important traits in native goats. Full article
(This article belongs to the Section Animal Genetics and Genomics)
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20 pages, 333 KiB  
Article
Comparing Domain Expert and Machine Learning Data Enrichment of Building Registry
by Ants Torim, Elisa Iliste, Ergo Pikas, Innar Liiv, Tarmo Robal and Targo Kalamees
Buildings 2025, 15(11), 1798; https://doi.org/10.3390/buildings15111798 - 24 May 2025
Viewed by 374
Abstract
Municipal decision-makers must define and quantitatively analyze full-renovation scenarios adapted to specific districts and buildings to achieve the European Union (EU) target of saving 60% to 90% of energy by renovating 75% of building stock. However, poor open-data quality presents a tenacious challenge, [...] Read more.
Municipal decision-makers must define and quantitatively analyze full-renovation scenarios adapted to specific districts and buildings to achieve the European Union (EU) target of saving 60% to 90% of energy by renovating 75% of building stock. However, poor open-data quality presents a tenacious challenge, especially for automatic calculations or decision-making. This study addresses the challenge of enriching Estonian Building Registry (EBR) data by predicting the actual external wall type from existing registry information. To achieve this, both domain expert rules and machine learning models were employed. The study used a training dataset of 416 buildings and a test dataset of 66 buildings. While previous research comparing expert-based and machine learning approaches has been limited and yielded mixed results, our findings demonstrate that both methods perform similarly, improving the initial wall type classification accuracy from 54% to 89%. Full article
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15 pages, 204 KiB  
Article
Enhancing Agricultural Productivity Among Emerging Farmers Through Data-Driven Practices
by Mzuhleli Makapela, Gregg Alexander and Molaodi Tshelane
Sustainability 2025, 17(10), 4666; https://doi.org/10.3390/su17104666 - 19 May 2025
Viewed by 513
Abstract
This paper explores the critical need for empowering emerging farmers within vulnerable communities through vocational adult education (VAE) approaches. Conducted within the Raymond Mhlaba District Municipality, South Africa, this study illuminates the persistent challenges of illiteracy, poverty, and the impact of climate change [...] Read more.
This paper explores the critical need for empowering emerging farmers within vulnerable communities through vocational adult education (VAE) approaches. Conducted within the Raymond Mhlaba District Municipality, South Africa, this study illuminates the persistent challenges of illiteracy, poverty, and the impact of climate change on agricultural productivity faced by these farmers. Employing a mixed-methods research design that combines quantitative and qualitative methodologies, this study investigates the effectiveness of digital agriculture and extension services in enhancing agricultural productivity and sustainability among emerging farmers. Key findings reveal significant barriers to technology adoption and the necessity for tailored training programs that integrate local knowledge systems and digital tools. Results demonstrate an average increase of 40% in crop yields among farmers participating in digital training initiatives (p < 0.01), underscoring the power of precision agriculture. Insights presented in this paper offer actionable recommendations for policymakers and stakeholders aimed at fostering inclusive agricultural development that addresses the unique challenges faced by emerging farmers in this region. Full article
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