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Keywords = multi-frequency electrical impedance tomography

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25 pages, 3545 KB  
Article
Machine Learning-Based Foreign Object Detection in Wireless EV Charging Using Planar Magnetic Induction Tomography
by Abdul Khader Abdul Vahid, Dorian Vargas-Reighley, Benjamin Warrington, Gavin Dingley and Manuchehr Solemani
Sensors 2026, 26(11), 3486; https://doi.org/10.3390/s26113486 - 1 Jun 2026
Viewed by 385
Abstract
Wireless power transfer (WPT) systems for electric vehicles require reliable foreign object detection (FOD) mechanisms both during and prior to power transfer to ensure operational safety and efficiency. The primary purpose of this study was to develop a foreign object detection system to [...] Read more.
Wireless power transfer (WPT) systems for electric vehicles require reliable foreign object detection (FOD) mechanisms both during and prior to power transfer to ensure operational safety and efficiency. The primary purpose of this study was to develop a foreign object detection system to ensure that no objects are present in the area of magnetic coupling (between primary and secondary coils) prior to initiating power transfer. Conventional FOD techniques based on impedance, visual light, or thermal monitoring provide limited spatial information and are sensitive to coil misalignment. This paper proposes a machine learning-based FOD approach using a planar Magnetic Inductance Tomography (MIT) sensor array that enables spatial electromagnetic sensing for early detection and localisation of conductive foreign objects. A dataset comprising 17,800 measurement frames was collected using a custom STM32-based data acquisition system in the absence of (prior to) power transfer. Likewise, a dataset comprising 300 sets of measurement frames was collected during power transfer, in which each frame contains 120 electromagnetic sensor readings. This capture methodology coincides with the detection requirements of live WPT systems. Four classification models, including Random Forest, Support Vector Machine, XGBoost, and Multi-Layer Perceptron, were evaluated. To enhance robustness against sensor drift and environmental variations, feature-engineering techniques incorporating statistical, temporal, frequency-domain, and derivative-based features were developed. Experimental results demonstrate high detection accuracy under both controlled and real-world conditions. The proposed approach demonstrates the feasibility of integrating machine learning-based MIT sensing into wireless EV charging infrastructure for reliable foreign object detection. Full article
(This article belongs to the Special Issue Sensors in 2026)
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22 pages, 1565 KB  
Article
Multifrequency Electrical Impedance Tomography Images for Swine Pneumonia Detection Using Conductivity Differences
by Julia Grasiela Busarello Wolff, Rafael Kingeski, Wellington Pinheiro dos Santos, José Cristani, Sandra Davi Traverso and Aleksander Sade Paterno
Electronics 2024, 13(8), 1463; https://doi.org/10.3390/electronics13081463 - 12 Apr 2024
Cited by 4 | Viewed by 2720
Abstract
This article introduces a new MfEIT UDESC Mark I system, which consists of a 32-electrode setup featuring a modified Howland current source, low cost, portability, and non-radiation. The system is capable of reconstructing electrical conductivity tomographic images at a rate of 30.624 frames [...] Read more.
This article introduces a new MfEIT UDESC Mark I system, which consists of a 32-electrode setup featuring a modified Howland current source, low cost, portability, and non-radiation. The system is capable of reconstructing electrical conductivity tomographic images at a rate of 30.624 frames per second, taking about 5 min for imaging. The current source employs a 0.5 mA adjacent current application pattern with frequencies ranging from 10 kHz to 1 MHz. This article outlines the hardware, firmware, and software design specifications, which include the design of the current source, calibration procedures, and image reconstruction process. Tomographic images of conductivity were reconstructed in ex vivo healthy pig lungs and those with pneumonia, as a proof of concept for future applications in live pigs. The high spectral power density, combined with real-time system calibration provides clinical advantages in veterinary medicine. The goal is to identify lung areas affected by Mycoplasma hyopneumoniae in pigs through the analysis of electrical conductivity difference, offering a valuable tool to assist veterinarians to obtain images of respiratory diseases. The modified reconstruction method GREIT (EIDORS) was evaluated with experimental data and was compared with the Gauss–Newton and Total Variation methods, where GREIT 2D proved to be superior. Full article
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17 pages, 5842 KB  
Article
Algorithms for Optimizing Energy Consumption for Fermentation Processes in Biogas Production
by Grzegorz Rybak, Edward Kozłowski, Krzysztof Król, Tomasz Rymarczyk, Agnieszka Sulimierska, Artur Dmowski and Piotr Bednarczuk
Energies 2023, 16(24), 7972; https://doi.org/10.3390/en16247972 - 8 Dec 2023
Cited by 13 | Viewed by 2043
Abstract
Problems related to reducing energy consumption constitute an important basis for scientific research worldwide. A proposal to use various renewable energy sources, including creating a biogas plant, is emphasized in the introduction of this article. However, the indicated solutions require continuous monitoring and [...] Read more.
Problems related to reducing energy consumption constitute an important basis for scientific research worldwide. A proposal to use various renewable energy sources, including creating a biogas plant, is emphasized in the introduction of this article. However, the indicated solutions require continuous monitoring and control to maximise the installations’ effectiveness. The authors took up the challenge of developing a computer solution to reduce the costs of maintaining technological process monitoring systems. Concept diagrams of a metrological system using multi-sensor techniques containing humidity, temperature and pressure sensors coupled with Electrical Impedance Tomography (EIT) sensors were presented. This approach allows for effective monitoring of the anaerobic fermentation process. The possibility of reducing the energy consumed during installation operation was proposed, which resulted in the development of algorithms for determining alarm states, which are the basis for controlling the frequency of technological process measurements. Implementing the idea required the preparation of measurement infrastructure and an analytical engine based on AI techniques, including an expert system and developed algorithms. Numerous time-consuming studies and experiments have confirmed reduced energy consumption, which can be successfully used in biogas production. Full article
(This article belongs to the Special Issue Applications of Electromagnetism in Energy Efficiency)
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25 pages, 9570 KB  
Article
Lumped Element Method Based Conductivity Reconstruction Algorithm for Localization Using Symmetric Discrete Operators on Coarse Meshes
by Zoltan Sari, Mihaly Klincsik, Peter Odry, Vladimir Tadic, Attila Toth and Zoltan Vizvari
Symmetry 2023, 15(5), 1008; https://doi.org/10.3390/sym15051008 - 30 Apr 2023
Cited by 4 | Viewed by 2379
Abstract
The inverse conductivity problem in electrical impedance tomography involves the solving of a nonlinear and under-determined system of equations. This paper presents a new approach, which leads to a quadratic and overdetermined system of equations. The aim of the paper is to establish [...] Read more.
The inverse conductivity problem in electrical impedance tomography involves the solving of a nonlinear and under-determined system of equations. This paper presents a new approach, which leads to a quadratic and overdetermined system of equations. The aim of the paper is to establish new research directions in handling of the inverse conductivity problem. The basis of the proposed method is that the material, which can be considered as an isotropic continuum, is modeled as a linear network with concentrated parameters. The weights of the obtained graph represent the properties of the discretized continuum. Further, the application of the developed procedure allows for the dielectric constant to be used in the multi-frequency approach, as a result of which the optimized system of equations always remains overdetermined. Through case studies, the efficacy of the reconstruction method by changing the mesh resolution applied for discretizing is presented and evaluated. The presented results show, that, due to the application of discrete, symmetric mathematical structures, the new approach even at coarse mesh resolution is capable of localizing the inhomogeneities of the material. Full article
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16 pages, 3723 KB  
Article
Using Novel Multi-Frequency Analysis Methods to Retrieve Material and Temperature Information in Tactile Sensing Areas
by Mehdi Abdelwahed, Lounis Zerioul, Alexandre Pitti and Olivier Romain
Sensors 2022, 22(22), 8876; https://doi.org/10.3390/s22228876 - 17 Nov 2022
Cited by 9 | Viewed by 3364
Abstract
This article presents a novel artificial skin technology based on the Electric Impedance Tomography (EIT) that employs multi-frequency currents for detecting the material and the temperature of objects in contact with piezoresistive sheets. To date, few artificial skins in the literature are capable [...] Read more.
This article presents a novel artificial skin technology based on the Electric Impedance Tomography (EIT) that employs multi-frequency currents for detecting the material and the temperature of objects in contact with piezoresistive sheets. To date, few artificial skins in the literature are capable of detecting an object’s material, e.g., wood, skin, leather, or plastic. EIT-based artificial skins have been employed mostly to detect the position of the contact but not its characteristics. Thanks to multi-frequency currents, our EIT-based artificial skin is capable of characterising the spectral profile of objects in contact and identifying an object’s material at ambient temperature. Moreover, our model is capable of detecting several levels of temperature (from −10 up to 60 °C) and can also maintain a certain accuracy for material identification. In addition to the known capabilities of EIT-based artificial skins concerning detecting pressure and location of objects, as well as being low cost, these two novel modalities demonstrate the potential of EIT-based artificial skins to achieve global tactile sensing. Full article
(This article belongs to the Special Issue Advances in Bio-Inspired Skin-Like Sensor Technologies)
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17 pages, 29995 KB  
Article
E-Skin Using Fringing Field Electrical Impedance Tomography with an Ionic Liquid Domain
by Manuchehr Soleimani and Myron Friedrich
Sensors 2022, 22(13), 5040; https://doi.org/10.3390/s22135040 - 4 Jul 2022
Cited by 16 | Viewed by 5302
Abstract
Electrical impedance tomography (EIT) is a promising technique for large area tactile sensing for robotic skin. This study presents a novel EIT-based force and touch sensor that features a latex membrane acting as soft skin and an ionic liquid domain. The sensor works [...] Read more.
Electrical impedance tomography (EIT) is a promising technique for large area tactile sensing for robotic skin. This study presents a novel EIT-based force and touch sensor that features a latex membrane acting as soft skin and an ionic liquid domain. The sensor works based on fringing field EIT where the touch or force leads to a deformation in the latex membrane causing detectable changes in EIT data. This article analyses the performance of this electronic skin in terms of its dynamical behaviour, position accuracy and quantitative force sensing. Investigation into the sensor’s performance showed it to be hypersensitive, in that it can reliably detect forces as small as 64 mN. Furthermore, multi-touch discrimination and annular force sensing is displayed. The hysteresis in force sensing is investigated showing a very negligible hysteresis. This is a direct result of the latex membrane and the ionic liquid-based domain design compared to more traditional fabric-based touch sensors due to the reduction in electromechanical coupling. A novel test is devised that displayed the dynamic performance of the sensor by showing its ability to record a 1 Hz frequency, which was applied to the membrane in a tapping fashion. Overall, the results show a considerable progress in ionic liquid EIT-based sensors. These findings place the EIT-based sensors that comprise a liquid domain, at the forefront of research into tactile robotic skin. Full article
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28 pages, 11784 KB  
Article
A Rapid, Low-Cost, and High-Precision Multifrequency Electrical Impedance Tomography Data Acquisition System for Plant Phenotyping
by Rinku Basak and Khan A. Wahid
Remote Sens. 2022, 14(13), 3214; https://doi.org/10.3390/rs14133214 - 4 Jul 2022
Cited by 14 | Viewed by 5310
Abstract
Plant phenotyping plays an important role for the thorough assessment of plant traits such as growth, development, and physiological processes with the target of achieving higher crop yields by the proper crop management. The assessment can be done by utilizing two- and three-dimensional [...] Read more.
Plant phenotyping plays an important role for the thorough assessment of plant traits such as growth, development, and physiological processes with the target of achieving higher crop yields by the proper crop management. The assessment can be done by utilizing two- and three-dimensional image reconstructions of the inhomogeneities. The quality of the reconstructed image is required to maintain a high accuracy and a good resolution, and it is desirable to reconstruct the images with the lowest possible noise. In this work, an electrical impedance tomography (EIT) data acquisition system is developed for the reconstruction and evaluation of the inhomogeneities by utilizing a non-destructive method. A high-precision EIT system is developed by designing an electrode array sensor using a cylindrical domain for the measurements in different planes. Different edible plant slices along with multiple plant roots are taken in the EIT domain to assess and calibrate the system, and their reconstructed results are evaluated by utilizing an impedance imaging technique. A non-invasive imaging is carried out in multiple frequencies by utilizing a difference method of reconstruction. The performance and accuracy of the EIT system are evaluated by measuring impedances between 1 and 100 kHz using a low-cost and rapid electrical impedance spectroscopy (EIS) tool connected to the sensor. A finite element method (FEM) modeling is utilized for image reconstruction, which is carried out using electrical impedance and diffuse optical tomography reconstruction software (EIDORS). The reconstruction is made successfully with the optimized results obtained using Gauss–Newton (GN) algorithms. Full article
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17 pages, 5243 KB  
Article
Multifrequency Impedance Tomography System for Research on Environmental and Thermal Processes
by Jan Porzuczek
Energies 2021, 14(19), 6366; https://doi.org/10.3390/en14196366 - 5 Oct 2021
Cited by 2 | Viewed by 3270
Abstract
The possibility for spatial and temporal monitoring of environmental, chemical or thermal processes is of high importance for their better understanding thus control and optimization. Therefore, measurement methods that enable such opportunities might be especially valuable for researchers and process engineers. For this [...] Read more.
The possibility for spatial and temporal monitoring of environmental, chemical or thermal processes is of high importance for their better understanding thus control and optimization. Therefore, measurement methods that enable such opportunities might be especially valuable for researchers and process engineers. For this reason, in this paper the novel Electrical Impedance Tomography system is proposed that enables the visualization of the processes in which the electrical conductivity of material is changing. The proposed EIT system is based mostly on general purpose equipment. It consists of three laboratory-grade devices: a signal generator, a switching device and a data acquisition card for voltage measurement. In addition to those devices, the current source was constructed to complete the system. The EIT system was designed to have the ability of sourcing the current of frequency up to 250 kHz. A set of validation experiments were carried out to verify the EIT system accuracy. The validation tests consisted of object detection, distinguishing between objects of different conductivity, multifrequency imaging and visualization of slow-changing processes. The obtained results were also compared with the numerical simulations. The proposed system was proven to have the ability of correct imaging of irregularity inside the area of the sensor. Full article
(This article belongs to the Special Issue Computational Thermal, Energy, and Environmental Engineering)
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24 pages, 3051 KB  
Article
Feasibility of Temperature Control by Electrical Impedance Tomography in Hyperthermia
by Redi Poni, Esra Neufeld, Myles Capstick, Stephan Bodis, Theodoros Samaras and Niels Kuster
Cancers 2021, 13(13), 3297; https://doi.org/10.3390/cancers13133297 - 30 Jun 2021
Cited by 12 | Viewed by 3527
Abstract
We present a simulation study investigating the feasibility of electrical impedance tomography (EIT) as a low cost, noninvasive technique for hyperthermia (HT) treatment monitoring and adaptation. Temperature rise in tissues leads to perfusion and tissue conductivity changes that can be reconstructed in 3D [...] Read more.
We present a simulation study investigating the feasibility of electrical impedance tomography (EIT) as a low cost, noninvasive technique for hyperthermia (HT) treatment monitoring and adaptation. Temperature rise in tissues leads to perfusion and tissue conductivity changes that can be reconstructed in 3D by EIT to noninvasively map temperature and perfusion. In this study, we developed reconstruction methods and investigated the achievable accuracy of EIT by simulating HT treatmentlike scenarios, using detailed anatomical models with heterogeneous conductivity distributions. The impact of the size and location of the heated region, the voltage measurement signal-to-noise ratio, and the reference model personalization and accuracy were studied. Results showed that by introducing an iterative reconstruction approach, combined with adaptive prior regions and tissue-dependent penalties, planning-based reference models, measurement-based reweighting, and physics-based constraints, it is possible to map conductivity-changes throughout the heated domain, with an accuracy of around 5% and cm-scale spatial resolution. An initial exploration of the use of multifrequency EIT to separate temperature and perfusion effects yielded promising results, indicating that temperature reconstruction accuracy can be in the order of 1 °C. Our results suggest that EIT can provide valuable real-time HT monitoring capabilities. Experimental confirmation in real-world conditions is the next step. Full article
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19 pages, 2242 KB  
Review
A Review on Electrical Impedance Tomography Spectroscopy
by Juliana Padilha Leitzke and Hubert Zangl
Sensors 2020, 20(18), 5160; https://doi.org/10.3390/s20185160 - 10 Sep 2020
Cited by 34 | Viewed by 9920
Abstract
Electrical Impedance Tomography Spectroscopy (EITS) enables the reconstruction of material distributions inside an object based on the frequency-dependent characteristics of different substances. In this paper, we present a review of EITS focusing on physical principles of the technology, sensor geometries, existing measurement systems, [...] Read more.
Electrical Impedance Tomography Spectroscopy (EITS) enables the reconstruction of material distributions inside an object based on the frequency-dependent characteristics of different substances. In this paper, we present a review of EITS focusing on physical principles of the technology, sensor geometries, existing measurement systems, reconstruction algorithms, and image representation methods. In addition, a novel imaging method is proposed which could fill some of the gaps found in the literature. As an example of an application, EITS of ice and water mixtures is used. Full article
(This article belongs to the Special Issue Tomography Sensing Technologies)
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21 pages, 7376 KB  
Article
Process Monitoring of Antisolvent Based Crystallization in Low Conductivity Solutions Using Electrical Impedance Spectroscopy and 2-D Electrical Resistance Tomography
by Guruprasad Rao, Soheil Aghajanian, Tuomas Koiranen, Radosław Wajman and Lidia Jackowska-Strumiłło
Appl. Sci. 2020, 10(11), 3903; https://doi.org/10.3390/app10113903 - 4 Jun 2020
Cited by 20 | Viewed by 5161
Abstract
Industrial process monitoring is an important field of research where different chemical processes are monitored and controlled. In this work, electrical impedance spectroscopy (EIS) was used to analyze antisolvent based crystallization of sucrose solutions. The impedance and phase spectra were recorded for four [...] Read more.
Industrial process monitoring is an important field of research where different chemical processes are monitored and controlled. In this work, electrical impedance spectroscopy (EIS) was used to analyze antisolvent based crystallization of sucrose solutions. The impedance and phase spectra were recorded for four known sucrose concentrations in water, and for each case, four predetermined amounts of ethanol were added. As a result, sixteen different solutions involving sucrose solutions of different concentrations and ethanol to water ratios were analyzed. Significant differences were observed in the magnitude and phase spectra of the solutions in the frequency range of 50 kHz to 300 kHz. The experimentally obtained data from the EIS were converted into frequency response models. Three continuous-time transfer function models of the first-order, second-order, and a second-order with a zero were estimated and compared. In addition, a 2-D electrical resistance tomography (ERT) system with a low conductivity sensor unit was designed and tested with demineralized water, tap water and industrial food grade saturated sucrose solution. Non-conducting phantom and sugar crystals were observed within the saturated sucrose solution using the Bayesian reconstruction algorithm. These demonstrations have the potential to be developed into a multi-frequency ERT systems for monitoring the distribution of the crystals in the reactor. The EIS modality can be a complementary process analytical technology (PAT) tool indicating supersaturation status and provide quality assurance. Full article
(This article belongs to the Section Applied Industrial Technologies)
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19 pages, 11559 KB  
Article
On the Implementation of Simultaneous Multi-Frequency Excitations and Measurements for Electrical Impedance Tomography
by Mathieu Darnajou, Antoine Dupré, Chunhui Dang, Guillaume Ricciardi, Salah Bourennane and Cédric Bellis
Sensors 2019, 19(17), 3679; https://doi.org/10.3390/s19173679 - 24 Aug 2019
Cited by 13 | Viewed by 5460
Abstract
The investigation of quickly-evolving flow patterns in high-pressure and high-temperature flow rigs requires the use of a high-speed and non-intrusive imaging technique. Electrical Impedance Tomography (EIT) allows reconstructing the admittivity distribution characterizing a flow from the knowledge of currents and voltages on its [...] Read more.
The investigation of quickly-evolving flow patterns in high-pressure and high-temperature flow rigs requires the use of a high-speed and non-intrusive imaging technique. Electrical Impedance Tomography (EIT) allows reconstructing the admittivity distribution characterizing a flow from the knowledge of currents and voltages on its periphery. The need for images at high frame rates leads to the strategy of simultaneous multi-frequency voltage excitations and simultaneous current measurements, which are discriminated using fast Fourier transforms. The present study introduces the theory for a 16-electrode simultaneous EIT system, which is then built based on a field programmable gate array data acquisition system. An analysis of the propagation of uncertainties through the measurement process is investigated, and experimental results with fifteen simultaneous signals are presented. It is shown that the signals are successfully retrieved experimentally at a rate of 1953 frames per second. The associated signal-to-noise ratio varies from 59.6–69.1 dB, depending on the generated frequency. These preliminary results confirm the relevance and the feasibility of simultaneous multi-frequency excitations and measurements in EIT as a means to significantly increase the imaging rate. Full article
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16 pages, 4587 KB  
Article
In Vivo Bioimpedance Spectroscopy Characterization of Healthy, Hemorrhagic and Ischemic Rabbit Brain within 10 Hz–1 MHz
by Lin Yang, Wenbo Liu, Rongqing Chen, Ge Zhang, Weichen Li, Feng Fu and Xiuzhen Dong
Sensors 2017, 17(4), 791; https://doi.org/10.3390/s17040791 - 7 Apr 2017
Cited by 31 | Viewed by 7162
Abstract
Acute stroke is a serious cerebrovascular disease and has been the second leading cause of death worldwide. Conventional diagnostic modalities for stroke, such as CT and MRI, may not be available in emergency settings. Hence, it is imperative to develop a portable tool [...] Read more.
Acute stroke is a serious cerebrovascular disease and has been the second leading cause of death worldwide. Conventional diagnostic modalities for stroke, such as CT and MRI, may not be available in emergency settings. Hence, it is imperative to develop a portable tool to diagnose stroke in a timely manner. Since there are differences in impedance spectra between normal, hemorrhagic and ischemic brain tissues, multi-frequency electrical impedance tomography (MFEIT) shows great promise in detecting stroke. Measuring the impedance spectra of healthy, hemorrhagic and ischemic brain in vivo is crucial to the success of MFEIT. To our knowledge, no research has established hemorrhagic and ischemic brain models in the same animal and comprehensively measured the in vivo impedance spectra of healthy, hemorrhagic and ischemic brain within 10 Hz–1 MHz. In this study, the intracerebral hemorrhage and ischemic models were established in rabbits, and then the impedance spectra of healthy, hemorrhagic and ischemic brain were measured in vivo and compared. The results demonstrated that the impedance spectra differed significantly between healthy and stroke-affected brain (i.e., hemorrhagic or ischemic brain). Moreover, the rate of change in brain impedance following hemorrhagic and ischemic stroke with regard to frequency was distinct. These findings further validate the feasibility of using MFEIT to detect stroke and differentiate stroke types, and provide data supporting for future research. Full article
(This article belongs to the Section Biosensors)
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20 pages, 1804 KB  
Article
A Versatile and Reproducible Multi-Frequency Electrical Impedance Tomography System
by James Avery, Thomas Dowrick, Mayo Faulkner, Nir Goren and David Holder
Sensors 2017, 17(2), 280; https://doi.org/10.3390/s17020280 - 31 Jan 2017
Cited by 94 | Viewed by 12184
Abstract
A highly versatile Electrical Impedance Tomography (EIT) system, nicknamed the ScouseTom, has been developed. The system allows control over current amplitude, frequency, number of electrodes, injection protocol and data processing. Current is injected using a Keithley 6221 current source, and voltages are recorded [...] Read more.
A highly versatile Electrical Impedance Tomography (EIT) system, nicknamed the ScouseTom, has been developed. The system allows control over current amplitude, frequency, number of electrodes, injection protocol and data processing. Current is injected using a Keithley 6221 current source, and voltages are recorded with a 24-bit EEG system with minimum bandwidth of 3.2 kHz. Custom PCBs interface with a PC to control the measurement process, electrode addressing and triggering of external stimuli. The performance of the system was characterised using resistor phantoms to represent human scalp recordings, with an SNR of 77.5 dB, stable across a four hour recording and 20 Hz to 20 kHz. In studies of both haeomorrhage using scalp electrodes, and evoked activity using epicortical electrode mats in rats, it was possible to reconstruct images matching established literature at known areas of onset. Data collected using scalp electrode in humans matched known tissue impedance spectra and was stable over frequency. The experimental procedure is software controlled and is readily adaptable to new paradigms. Where possible, commercial or open-source components were used, to minimise the complexity in reproduction. The hardware designs and software for the system have been released under an open source licence, encouraging contributions and allowing for rapid replication. Full article
(This article belongs to the Section Biosensors)
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16 pages, 5497 KB  
Article
Ex-Vivo Characterization of Bioimpedance Spectroscopy of Normal, Ischemic and Hemorrhagic Rabbit Brain Tissue at Frequencies from 10 Hz to 1 MHz
by Lin Yang, Ge Zhang, Jiali Song, Meng Dai, Canhua Xu, Xiuzhen Dong and Feng Fu
Sensors 2016, 16(11), 1942; https://doi.org/10.3390/s16111942 - 18 Nov 2016
Cited by 36 | Viewed by 7571
Abstract
Stroke is a severe cerebrovascular disease and is the second greatest cause of death worldwide. Because diagnostic tools (CT and MRI) to detect acute stroke cannot be used until the patient reaches the hospital setting, a portable diagnostic tool is urgently needed. Because [...] Read more.
Stroke is a severe cerebrovascular disease and is the second greatest cause of death worldwide. Because diagnostic tools (CT and MRI) to detect acute stroke cannot be used until the patient reaches the hospital setting, a portable diagnostic tool is urgently needed. Because biological tissues have different impedance spectra under normal physiological conditions and different pathological states, multi-frequency electrical impedance tomography (MFEIT) can potentially detect stroke. Accurate impedance spectra of normal brain tissue (gray and white matter) and stroke lesions (ischemic and hemorrhagic tissue) are important elements when studying stroke detection with MFEIT. To our knowledge, no study has comprehensively measured the impedance spectra of normal brain tissue and stroke lesions for the whole frequency range of 1 MHz within as short as possible an ex vivo time and using the same animal model. In this study, we established intracerebral hemorrhage and ischemic models in rabbits, then measured and analyzed the impedance spectra of normal brain tissue and stroke lesions ex vivo within 15 min after animal death at 10 Hz to 1 MHz. The results showed that the impedance spectra of stroke lesions significantly differed from those of normal brain tissue; the ratio of change in impedance of ischemic and hemorrhagic tissue with regard to frequency was distinct; and tissue type could be discriminated according to its impedance spectra. These findings further confirm the feasibility of detecting stroke with MFEIT and provide data supporting further study of MFEIT to detect stroke. Full article
(This article belongs to the Section Biosensors)
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