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Search Results (926)

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53 pages, 1141 KiB  
Review
Factors Associated with Perceived Coercion in Adults Receiving Psychiatric Care: A Scoping Review
by Clara Lessard-Deschênes, Pierre Pariseau-Legault, Vincent Billé, Sophie Sergerie-Richard, Emilie Hudson, Benedetta Silva, Jean-Simon Drouin, Marie Désilets and Marie-Hélène Goulet
Healthcare 2025, 13(15), 1868; https://doi.org/10.3390/healthcare13151868 - 30 Jul 2025
Viewed by 357
Abstract
Background/Objectives: Perceived coercion has been associated with significant negative outcomes, including service avoidance and psychological distress. Despite growing interest, no recent comprehensive review has mapped the full range of factors influencing this experience. This scoping review aimed to synthesize and present the state [...] Read more.
Background/Objectives: Perceived coercion has been associated with significant negative outcomes, including service avoidance and psychological distress. Despite growing interest, no recent comprehensive review has mapped the full range of factors influencing this experience. This scoping review aimed to synthesize and present the state of knowledge on the factors associated with perceived coercion by adults receiving psychiatric care. Methods: Following the Joanna Briggs Institute methodology, a systematic search of five databases and grey literature was conducted for publications from 1990 to 2025 in English and French. A total of 143 sources were included and thematically analyzed. Consultation with experts and individuals with lived experience enriched the interpretation of findings. Results: Five categories of factors were identified: individual, clinical, relational, legal, and structural. Relational and legal factors were most consistently associated with perceived coercion, while individual and clinical factors showed inconsistent findings. Structural influences were underexamined but significantly shaped the experiences of the individuals receiving care. Conclusions: Perceived coercion arises from a complex dynamic of individual, relational, and systemic influences. Reducing coercion requires moving beyond individual-level factors to address structural conditions and policy frameworks. Future research should prioritize qualitative and intersectional approaches and amplify the voices of those most affected by coercive practices in psychiatric care. Full article
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26 pages, 504 KiB  
Article
Exploring the Role of Social Protection in UK Asylum-Seeker Wellbeing Using Human Scale Development Theory
by Michelle James and Rachel Forrester-Jones
Soc. Sci. 2025, 14(8), 474; https://doi.org/10.3390/socsci14080474 - 30 Jul 2025
Viewed by 311
Abstract
This article utilises Max-Neef’s Human Scale Development (HSD) framework (1991) to answer two research questions: what impact does government and community-based social protection (SP) have on UK asylum-seeker wellbeing; how are interactions with all forms of SP, both as giver and receiver, supporting [...] Read more.
This article utilises Max-Neef’s Human Scale Development (HSD) framework (1991) to answer two research questions: what impact does government and community-based social protection (SP) have on UK asylum-seeker wellbeing; how are interactions with all forms of SP, both as giver and receiver, supporting or harming the satisfaction of asylum-seekers’ fundamental human needs at this time? The research study utilised a mixed-methods, collaborative, case study design situated within a refugee and asylum-seeker (RAS) support charity in Southwest England. Methods included peer-led Qualitative Impact Protocol interviews, Photovoice, surveys, and staff interviews. Data were subjected to an inductive, bottom-up process on Causal Map software (version 2, Causal Map Ltd., 39 Apsley Rd., Bath BA1 3LP, UK) and the analysis used the HSD framework. We found eight over-arching themes. The four main needs-violators/destroyers of asylum-seeker wellbeing were dehumanisation, unfreedoms, enforced ignorance, and (re)traumatisation, and the four main needs-satisfiers were common humanity, autonomy and resistance, exerting agency through knowledge exchange, and healing. Five policy and practice-focused bridging satisfiers are recommended to help move individual and collective experience from a negative to a positive state in the research population. Policy and practice should be transparent and evidence-based, efficient and equitable, supportive of participation and productivity, trauma-informed, and multi-agency. Full article
(This article belongs to the Section International Migration)
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32 pages, 18111 KiB  
Article
Across-Beam Signal Integration Approach with Ubiquitous Digital Array Radar for High-Speed Target Detection
by Le Wang, Haihong Tao, Aodi Yang, Fusen Yang, Xiaoyu Xu, Huihui Ma and Jia Su
Remote Sens. 2025, 17(15), 2597; https://doi.org/10.3390/rs17152597 - 25 Jul 2025
Viewed by 189
Abstract
Ubiquitous digital array radar (UDAR) extends the integration time of moving targets by deploying a wide transmitting beam and multiple narrow receiving beams to cover the entire observed airspace. By exchanging time for energy, it effectively improves the detection ability for weak targets. [...] Read more.
Ubiquitous digital array radar (UDAR) extends the integration time of moving targets by deploying a wide transmitting beam and multiple narrow receiving beams to cover the entire observed airspace. By exchanging time for energy, it effectively improves the detection ability for weak targets. Nevertheless, target motion introduces severe across-range unit (ARU), across-Doppler unit (ADU), and across-beam unit (ABU) effects, dispersing target energy across the range–Doppler-beam space. This paper proposes a beam domain angle rotation compensation and keystone-matched filtering (BARC-KTMF) algorithm to address the “three-crossing” challenge. This algorithm first corrects ABU by rotating beam–domain coordinates to align scattered energy into the final beam unit, reshaping the signal distribution pattern. Then, the KTMF method is utilized to focus target energy in the time-frequency domain. Furthermore, a special spatial windowing technique is developed to improve computational efficiency through parallel block processing. Simulation results show that the proposed approach achieves an excellent signal-to-noise ratio (SNR) gain over the typical single-beam and multi-beam long-time coherent integration (LTCI) methods under low SNR conditions. Additionally, the presented algorithm also has the capability of coarse estimation for the target incident angle. This work extends the LTCI technique to the beam domain, offering a robust framework for high-speed weak target detection. Full article
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16 pages, 236 KiB  
Article
Disability Certification in Colombia: An Analysis from the Perspective of Inclusive Social Protection
by Monica Pinilla-Roncancio and Nicolas Rodriguez Caicedo
Disabilities 2025, 5(3), 66; https://doi.org/10.3390/disabilities5030066 - 25 Jul 2025
Viewed by 470
Abstract
Disability Certification is an instrument that can contribute to the identification of persons with disabilities who are potential beneficiaries of social protection programmes. In Colombia, the disability certification process was changed in 2020 to include a human rights perspective. However, little information exists [...] Read more.
Disability Certification is an instrument that can contribute to the identification of persons with disabilities who are potential beneficiaries of social protection programmes. In Colombia, the disability certification process was changed in 2020 to include a human rights perspective. However, little information exists on how far the process aligns with the recommendations made by the Convention on the Rights of Persons with Disabilities or to what extent it provides useful information for the operation of the country’s social protection system. This study aims to analyse how the changes implemented in 2020 have contributed to the identification and determination of persons with disabilities in social protection programmes in Colombia. This research uses an analytical-descriptive design, in which legal documents related to the social protection programme and disability certification were analysed. In addition, we conducted semi-structured interviews in Colombia with people with disabilities, professionals conducting the certification, and with key stakeholders, and we analysed the information using thematic analysis. Colombia changed its certification process in 2020, moving from a capacity-to-work assessment to a process of assessing functioning capacity and participation limitations following the International Classification of Functional Disability and Health. However, the new certification process has not provided an instrument to contribute to determining persons with disabilities who should be prioritised or receive social benefits in Colombia. The certification does not establish the support needs of people with disabilities, does not recommend reasonable adjustments to support their participation in society, and has not been used systematically in social protection programmes. Finally, individuals with disabilities commented that the disability certification is a process that does not open up opportunities to receive social benefits and social transfers, and in most cases, it is an expensive and lengthy process. Disability certification in Colombia is not an instrument that determines the needs of people with disabilities, nor the reasonable accommodations that they require in order to participate in society. Full article
25 pages, 2486 KiB  
Article
Influence of Intense Internal Waves Traveling Along an Acoustic Path on Source Holographic Reconstruction in Shallow Water
by Sergey Pereselkov, Venedikt Kuz’kin, Matthias Ehrhardt, Sergey Tkachenko, Alexey Pereselkov and Nikolay Ladykin
J. Mar. Sci. Eng. 2025, 13(8), 1409; https://doi.org/10.3390/jmse13081409 - 24 Jul 2025
Viewed by 293
Abstract
This paper studies how intense internal waves (IIWs) affect the holographic reconstruction of the sound field generated by a moving source in a shallow-water environment. It is assumed that the IIWs propagate along the acoustic path between the source and the receiver. The [...] Read more.
This paper studies how intense internal waves (IIWs) affect the holographic reconstruction of the sound field generated by a moving source in a shallow-water environment. It is assumed that the IIWs propagate along the acoustic path between the source and the receiver. The presence of IIWs introduces inhomogeneities into the waveguide and causes significant mode coupling, which perturbs the received sound field. This paper proposes the use of holographic signal processing (HSP) to eliminate perturbations in the received signal caused by mode coupling due to IIWs. Within the HSP framework, we examine the interferogram (the received sound intensity distribution in the frequency–time domain) and the hologram (the two-dimensional Fourier transform of the interferogram) of a moving source in the presence of space–time inhomogeneities caused by IIWs. A key finding is that under the influence of IIWs, the hologram is divided into two regions that correspond to the unperturbed and perturbed components of the sound field. This hologram structure enables the extraction and reconstruction of the interferogram corresponding to the unperturbed field as it would appear in a shallow-water waveguide without IIWs. Numerical simulations of HSP application under the realistic conditions of the SWARM’95 experiment were carried out for stationary and moving sources. The results demonstrate the high efficiency of holographic reconstruction of the unperturbed sound field. Unlike matched field processing (MFP), HSP does not require prior knowledge of the propagation environment. These research results advance signal processing methods in underwater acoustics by introducing efficient HSP methods for environments with spatiotemporal inhomogeneities. Full article
(This article belongs to the Section Physical Oceanography)
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16 pages, 3620 KiB  
Article
Wind Tunnel Experimental Study on Dynamic Coupling Characteristics of Flexible Refueling Hose–Drogue System
by Yinzhu Wang, Jiangtao Huang, Qisheng Chen, Enguang Shan and Yufeng Guo
Aerospace 2025, 12(7), 646; https://doi.org/10.3390/aerospace12070646 - 21 Jul 2025
Viewed by 160
Abstract
During the process of flexible aerial refueling, the flexible structure of the hose drogue assembly is affected by internal and external interference, such as docking maneuvering, deformation of the hose, attitude changes, and body vibrations, causing the hose to swing and the whipping [...] Read more.
During the process of flexible aerial refueling, the flexible structure of the hose drogue assembly is affected by internal and external interference, such as docking maneuvering, deformation of the hose, attitude changes, and body vibrations, causing the hose to swing and the whipping phenomenon, which greatly limits the success rate and safety of aerial refueling operations. Based on a 2.4 m transonic wind tunnel, high-speed wind tunnel test technology of a flexible aerial refueling hose–drogue system was established to carry out experimental research on the coupling characteristics of aerodynamics and multi-body dynamics. Based on the aid of Videogrammetry Model Deformation (VMD), high-speed photography, dynamic balance, and other wind tunnel test technologies, the dynamic characteristics of the hose–drogue system in a high-speed airflow and during the approach of the receiver are obtained. Adopting flexible multi-body dynamics, a dynamic system of the tanker, hose, drogue, and receiver is modeled. The cable/beam model is based on an arbitrary Lagrange–Euler method, and the absolute node coordinate method is used to describe the deformation, movement, and length variation in the hose during both winding and unwinding. The aerodynamic forces of the tanker, receiver, hose, and drogue are modeled, reflecting the coupling influence of movement of the tanker and receiver, the deformation of the hose and drogue, and the aerodynamic forces on each other. The tests show that during the approach of the receiver (distance from 1000 mm to 20 mm), the sinking amount of the drogue increases by 31 mm; due to the offset of the receiver probe, the drogue moves sideways from the symmetric plane of the receiver. Meanwhile, the oscillation magnitude of the drogue increases (from 33 to 48 and from 48 to 80 in spanwise and longitudinal directions, respectively). The simulation results show that the shear force induced by the oscillation of the hose and the propagation velocity of both the longitudinal and shear waves are affected by the hose stiffness and Mach number. The results presented in this work can be of great reference to further increase the safety of aerial refueling. Full article
(This article belongs to the Section Aeronautics)
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11 pages, 879 KiB  
Review
The Implications of Type 1 Diabetes Mellitus Associated with Coeliac Disease
by Geoffrey Holmes and Peter Gillett
J. Clin. Med. 2025, 14(14), 5129; https://doi.org/10.3390/jcm14145129 - 18 Jul 2025
Viewed by 506
Abstract
T1D and CD commonly occur together. This association has received increasing attention from researchers and is considered in detail in this review. Since CD is over-represented in T1D, it may cause ill health with attendant complications, but because there is an effective dietary [...] Read more.
T1D and CD commonly occur together. This association has received increasing attention from researchers and is considered in detail in this review. Since CD is over-represented in T1D, it may cause ill health with attendant complications, but because there is an effective dietary treatment, screening has been recommended in children and adults. However, there are many unknowns regarding this association, and understanding the why, when, and how with regard to screening and managing those with dual diagnoses requires thorough consideration when introducing the concept of screening to patients. It is important that patients and, where appropriate, carers are put at the heart of the decision-making process with careful discussion of the issues involved before undertaking screening that might uncover a second life-changing diagnosis, for which, without preparatory preparation and support, individuals may be ill-prepared, causing mental health issues. For some patients, an initial policy of monitoring rather than moving to immediate small bowel biopsy and exposure to a gluten-free diet (GFD) will be appropriate. The correct management of patients will ultimately improve their quality of life medically and socially. Full article
(This article belongs to the Special Issue Future Trends in the Diagnosis and Management of Celiac Disease)
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16 pages, 185 KiB  
Article
The Music Next Door
by John H. Marks
Humanities 2025, 14(7), 146; https://doi.org/10.3390/h14070146 - 10 Jul 2025
Viewed by 284
Abstract
Ninety-five-year-old Doris Held, a great niece of Sigmund Freud, has been convening the Shakespeare Reading Group in Northampton, Massachusetts, my hometown, since she moved here in 2016. In the following essay, which is a personal response to my experience of this group of [...] Read more.
Ninety-five-year-old Doris Held, a great niece of Sigmund Freud, has been convening the Shakespeare Reading Group in Northampton, Massachusetts, my hometown, since she moved here in 2016. In the following essay, which is a personal response to my experience of this group of Shakespearean readers, to Doris Held, and to the work of Shakespeare in general, I attempt to chart the full impact of the Bard’s work on my life and on the world around me. I am neither a scholar nor a historian. In a true sense, I am a bystander Shakespearean, who has received deep reward and benefit from the experience, but it is Doris Held and her group who opened my eyes to the precise nature of this unexamined reward. Doris brought the spirit of the group from Cambridge, Massachusetts, where she had been a dues-paying member for decades of something called the Old Cambridge Shakespeare Association, which itself dates to 1880. My wife Debra and I attended the first meeting in Northampton more than a decade ago, and we have been receiving emails from Doris four times a year ever since. While these communications often induce guilt, they invariably lead to pleasures that I would never want to relinquish. That is a complicated dynamic in my routine, and I try to grapple with its ebb and flow in the pages that follow. Each time I get one, I have a version of the same conversation in my head. Is Doris still doing this? Haven’t they done all the plays by now? All things considered, wouldn’t they—and I—rather be home watching a true crime documentary about Gaby Petito on Netflix? What the hell is William Shakespeare to me anyway? At this point, if I’m honest, Shakespeare is Doris. The experience with this group led me in two directions. One took me back to my now long-ago history with Shakespeare’s work as an actor in college. The other took me via historical research into the prehistory of Doris Held’s previous Shakespeare group in Cambridge, Massachusetts. The two paths gave me a deeper grasp of the influence of his work across the world and on my own life. Full article
22 pages, 5135 KiB  
Article
Fast and Accurate Plane Wave and Color Doppler Imaging with the FOCUS Software Package
by Jacob S. Honer and Robert J. McGough
Sensors 2025, 25(14), 4276; https://doi.org/10.3390/s25144276 - 9 Jul 2025
Viewed by 351
Abstract
A comprehensive framework for ultrasound imaging simulations is presented. Solutions to an inhomogeneous wave equation are provided, yielding a linear model for characterizing ultrasound propagation and scattering in soft tissue. This simulation approach, which is based upon the fast nearfield method, is implemented [...] Read more.
A comprehensive framework for ultrasound imaging simulations is presented. Solutions to an inhomogeneous wave equation are provided, yielding a linear model for characterizing ultrasound propagation and scattering in soft tissue. This simulation approach, which is based upon the fast nearfield method, is implemented in the Fast Object-oriented C++ Ultrasound Simulator (FOCUS) and is extended to a range of imaging modalities, including synthetic aperture, B-mode, plane wave, and color Doppler imaging. The generation of radiofrequency (RF) data and the receive beamforming techniques employed for each imaging modality, along with background on color Doppler imaging, are described. Simulation results demonstrate rapid convergence and lower error rates compared to conventional spatial impulse response methods and Field II, resulting in substantial reductions in computation time. Notably, the framework effectively simulates hundreds of thousands of scatterers without the need for a full three-dimensional (3D) grid, and the inherent randomness in the scatterer distributions produces realistic speckle patterns. A plane wave imaging example, for instance, achieves high fidelity using 100,000 scatterers with five steering angles, and the simulation is completed on a personal computer in a few minutes. Furthermore, by modeling scatterers as moving particles, the simulation framework captures dynamic flow conditions in vascular phantoms for color Doppler imaging. These advances establish FOCUS as a robust, versatile tool for the rapid prototyping, validation, and optimization of both established and novel ultrasound imaging techniques. Full article
(This article belongs to the Special Issue Ultrasonic Imaging and Sensors II)
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18 pages, 2282 KiB  
Article
Quantifying the Unwinding Due to Ram Pressure Stripping in Simulated Galaxies
by Rubens E. G. Machado, Caroline F. O. Grinberg and Elvis A. Mello-Terencio
Galaxies 2025, 13(4), 76; https://doi.org/10.3390/galaxies13040076 - 7 Jul 2025
Viewed by 433
Abstract
Galaxies moving through the gas of the intracluster medium (ICM) experience ram pressure stripping, which can leave behind a gas tail. When a disk galaxy receives the wind edge-on, however, the characteristic signature is not a typical jellyfish tail, but rather an unwinding [...] Read more.
Galaxies moving through the gas of the intracluster medium (ICM) experience ram pressure stripping, which can leave behind a gas tail. When a disk galaxy receives the wind edge-on, however, the characteristic signature is not a typical jellyfish tail, but rather an unwinding of the spiral arms. We aim to quantify such asymmetries both in the gas and in the stellar component of a simulated galaxy. To this end, we simulate a gas-rich star-forming spiral galaxy moving through a self-consistent ICM gas. The amplitude and location of the asymmetries were measured via Fourier decomposition. We found that the asymmetry is much more evident in the gas component, but it is also measurable in the stars. The amplitude tends to increase with time and the asymmetry radius migrates inwards. We found that, when considering the gas, the spiral arms extend much further and are more unwound than the corresponding stellar arms. Characterizing the unwinding via simulations should help inform the observational criteria used to classify ram pressure stripped galaxies, as opposed to asymmetries induced by other mechanisms. Full article
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18 pages, 1513 KiB  
Article
Perceptual Decision Efficiency Is Modifiable and Associated with Decreased Musculoskeletal Injury Risk Among Female College Soccer Players
by Gary B. Wilkerson, Alejandra J. Gullion, Katarina L. McMahan, Lauren T. Brooks, Marisa A. Colston, Lynette M. Carlson, Jennifer A. Hogg and Shellie N. Acocello
Brain Sci. 2025, 15(7), 721; https://doi.org/10.3390/brainsci15070721 - 4 Jul 2025
Viewed by 317
Abstract
Background: Prevention and clinical management of musculoskeletal injuries have historically focused on the assessment and training of modifiable physical factors, but perceptual decision-making has only recently been recognized as a potentially important capability. Immersive virtual reality (VR) systems can measure the speed, accuracy, [...] Read more.
Background: Prevention and clinical management of musculoskeletal injuries have historically focused on the assessment and training of modifiable physical factors, but perceptual decision-making has only recently been recognized as a potentially important capability. Immersive virtual reality (VR) systems can measure the speed, accuracy, and consistency of body movements corresponding to stimulus–response instructions for the completion of a forced-choice task. Methods: A cohort of 26 female college soccer players (age 19.5 ± 1.3 years) included 10 players who participated in a baseline assessment, 10 perceptual-response training (PRT) sessions, a post-training assessment that preceded the first soccer practice, and a post-season assessment. The remaining 16 players completed an assessment prior to the team’s first pre-season practice session, and a post-season assessment. The assessments and training sessions involved left- or right-directed neck rotation, arm reach, and step-lunge reactions to 40 presentations of different types of horizontally moving visual stimuli. The PRT program included 4 levels of difficulty created by changes in initial stimulus location, addition of distractor stimuli, and increased movement speed, with ≥90% response accuracy used as the criterion for training progression. Perceptual latency (PL) was defined as the time elapsed from stimulus appearance to initiation of neck rotation toward a peripheral virtual target. The speed–accuracy tradeoff was represented by Rate Correct per Second (RCS) of PL, and inconsistency across trials derived from their standard deviation for PL was represented by intra-individual variability (IIV). Perceptual Decision Efficiency (PDE) represented the ratio of RCS to IIV, which provided a single value representing speed, accuracy, and consistency. Statistical procedures included the bivariate correlation between RCS and IIV, dependent t-test comparisons of pre- and post-training metrics, repeated measures analysis of variance for group X session pre- to post-season comparisons, receiver operating characteristic analysis, and Kaplan–Meier time to injury event analysis. Results: Statistically significant (p < 0.05) results were found for pre- to post-training change, and pre-season to post-season group differences, for RCS, IIV, and PDE. An inverse logarithmic relationship was found between RCS and IIV (Spearman’s Rho = −0.795). The best discriminator between injured and non-injured statuses was PDE ≤ 21.6 (93% Sensitivity; 42% Specificity; OR = 9.29). Conclusions: The 10-session PRT program produced significant improvement in perceptual decision-making that appears to provide a transfer benefit, as the PDE metric provided good prospective prediction of musculoskeletal injury. Full article
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12 pages, 232 KiB  
Review
Hypodiploidy: A Poor Prognostic Cytogenetic Marker in B-CLL
by Andrew Ruggero and Carlos A. Tirado
DNA 2025, 5(3), 32; https://doi.org/10.3390/dna5030032 - 1 Jul 2025
Viewed by 330
Abstract
In B-cell chronic lymphocytic leukemia (B-CLL), hypodiploidy is a rare but aggressive subtype of the disease with a very bad prognosis. Hypodiploidy, in contrast to normal B-CLL chromosomal aberrations, is marked by widespread genomic instability, which promotes treatment resistance and quick illness development. [...] Read more.
In B-cell chronic lymphocytic leukemia (B-CLL), hypodiploidy is a rare but aggressive subtype of the disease with a very bad prognosis. Hypodiploidy, in contrast to normal B-CLL chromosomal aberrations, is marked by widespread genomic instability, which promotes treatment resistance and quick illness development. Its persistence after treatment implies that chromosomal loss gives cancerous clones a selection edge, which is made worse by telomere malfunction and epigenetic changes. Since thorough genetic profiling has a major impact on patient outcomes, advanced diagnostic methods are crucial for early detection. Treatment approaches must advance beyond accepted practices because of its resistance to traditional medicines. Hematopoietic stem cell transplantation (HSCT) and chimeric antigen receptor (CAR) T-cell therapy are two potential new therapeutic modalities. Relapse and treatment-related morbidity continue to be limiting concerns, despite the noteworthy improvements in outcomes in high-risk CLL patients receiving HSCT. Although more research is required, CAR T-cell treatment is effective in treating recurrent B-ALL and may also be used to treat B-CLL with hypodiploidy. Novel approaches are essential for enhancing patient outcomes and redefining therapeutic success when hypodiploidy challenges established treatment paradigms. Hypodiploidy is an uncommon yet aggressive form of B-CLL that has a very bad prognosis. Hypodiploidy represents significant chromosomal loss and structural imbalance, which contributes to a disordered genomic environment, in contrast to more prevalent cytogenetic changes. This instability promotes resistance to certain new drugs as well as chemoimmunotherapy and speeds up clonal evolution. Its persistence after treatment implies that hypodiploid clones have benefits in survival, which are probably strengthened by chromosomal segregation issues and damaged DNA repair pathways. Malignant progression and treatment failure are further exacerbated by telomere erosion and epigenetic dysregulation. The need for more sensitive molecular diagnostics is highlighted by the fact that standard karyotyping frequently overlooks hypodiploid clones, particularly those concealed by endoreduplication, despite the fact that these complications make early and correct diagnosis crucial. Hypodiploidy requires a move toward individualized treatment because of their link to high-risk genetic traits and resistance to conventional regimens. Although treatments like hematopoietic stem cell transplantation and CAR T-cells show promise, long-term management is still elusive. To improve long-term results and avoid early relapse, addressing this cytogenetic population necessitates combining high-resolution genomic technologies with changing therapy approaches. Full article
20 pages, 2791 KiB  
Article
Assessment of Affordable Real-Time PPP Solutions for Transportation Applications
by Mohamed Abdelazeem, Amgad Abazeed, Abdulmajeed Alsultan and Amr M. Wahaballa
Algorithms 2025, 18(7), 390; https://doi.org/10.3390/a18070390 - 26 Jun 2025
Viewed by 246
Abstract
With the availability of multi-frequency, multi-constellation global navigation satellite system (GNSS) modules, precise transportation applications have become attainable. For transportation applications, GNSS geodetic-grade receivers can achieve an accuracy of a few centimeters to a few decimeters through differential, precise point positioning (PPP), real-time [...] Read more.
With the availability of multi-frequency, multi-constellation global navigation satellite system (GNSS) modules, precise transportation applications have become attainable. For transportation applications, GNSS geodetic-grade receivers can achieve an accuracy of a few centimeters to a few decimeters through differential, precise point positioning (PPP), real-time kinematic (RTK), and PPP-RTK solutions in both post-processing and real-time modes; however, these receivers are costly. Therefore, this research aims to assess the accuracy of a cost-effective multi-GNSS real-time PPP solution for transportation applications. For this purpose, the U-blox ZED-F9P module is utilized to collect dual-frequency multi-GNSS observations through a moving vehicle in a suburban area in New Aswan City, Egypt; thereafter, datasets involving different multi-GNSS combination scenarios are processed, including GPS, GPS/GLONASS, GPS/Galileo, and GPS/GLONASS/Galileo, using both RT-PPP and RTK solutions. For the RT-PPP solution, the satellite clock and orbit correction products from Bundesamt für Kartographie und Geodäsie (BKG), Centre National d’Etudes Spatiales (CNES), and the GNSS research center of Wuhan University (WHU) are applied to account for the real-time mode. Moreover, GNSS datasets from two geodetic-grade Trimble R4s receivers are collected; hence, the datasets are processed using the traditional kinematic differential solution to provide a reference solution. The results indicate that this cost-effective multi-GNSS RT-PPP solution can attain positioning accuracy within 1–3 dm, and is thus suitable for a variety of transportation applications, including intelligent transportation system (ITS), self-driving cars, and automobile navigation applications. Full article
(This article belongs to the Section Analysis of Algorithms and Complexity Theory)
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17 pages, 889 KiB  
Review
An Audiovisual Introduction to Streamer Physics
by Christoph Köhn
Atmosphere 2025, 16(7), 757; https://doi.org/10.3390/atmos16070757 - 20 Jun 2025
Viewed by 232
Abstract
Streamers are small, thin plasma channels that form the precursors of hot lightning leaders and that are associated with phenomena such as transient luminous events or terrestrial gamma-ray flashes. We provide an easily accessible audiovisual introduction for students and early researchers, serving as [...] Read more.
Streamers are small, thin plasma channels that form the precursors of hot lightning leaders and that are associated with phenomena such as transient luminous events or terrestrial gamma-ray flashes. We provide an easily accessible audiovisual introduction for students and early researchers, serving as a supplement to traditional review papers. This overview contains an introduction to the collision-dominated motion of electrons in an ambient field and an ambient gas, including a discussion of cross-sections and friction force. Based on this, we will discuss electron avalanches before moving to streamers. Here, we will focus on the avalanche-to-streamer transition and present properties and different modeling approaches. Finally, we will discuss streamers in different gas mixtures as well as their relation to lightning and plasma chemistry. The viewer of the supplementary video will receive a first overview of streamer physics. Full article
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24 pages, 1532 KiB  
Review
Climate Justice and Heat Inequity in Poor Urban Communities: The Lens of Transitional Justice, Green Climate Gentrification, and Adaptation Praxis
by Maxwell Fobi Kontor, Andre Brown and José Rafael Núñez Collado
Urban Sci. 2025, 9(6), 226; https://doi.org/10.3390/urbansci9060226 - 13 Jun 2025
Viewed by 794
Abstract
Urban heat stress is becoming increasingly urgent, yet it remains understudied within the broader intersection of climate change and spatial justice. While urban climate scholarship has largely focused on climatic impacts such as flooding, rising sea levels, and prolonged droughts, the socio-spatial lens [...] Read more.
Urban heat stress is becoming increasingly urgent, yet it remains understudied within the broader intersection of climate change and spatial justice. While urban climate scholarship has largely focused on climatic impacts such as flooding, rising sea levels, and prolonged droughts, the socio-spatial lens of urban heat in marginalised and low-income urban communities has received limited attention. This article, grounded in a systematic review of the global literature, foregrounds the mechanisms through which heat functions as a site of socio-environmental injustice. We argue that fragmented urban morphologies, entrenched spatial inequalities, and uneven adaptation strategies collectively produce and sustain heat vulnerability. The article identifies three interrelated conceptual framings that elucidate the production and persistence of heat inequity: transitional injustice, green climate gentrification, and intersectional adaptation praxis. These lenses reveal how heat risk is differentially distributed, governed, and experienced with broader discourses of urban marginalisation, environmental dispossession, and epistemic exclusion. We contend that advancing climate justice in the context of urban heat requires moving beyond technocratic and elite-oriented adaptation, toward multi-scalar planning paradigms that recognise embodied vulnerability, structural inequality, and the socio-political ecologies of thermal exposure. By theorising urban heat through the lens of climate justice, this article contributes to a more expansive and critical understanding of urban climate risk, one that situates heat inequity within the broader structures of power, governance, and spatial exclusion shaping contemporary urban environments. Full article
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