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34 pages, 513 KB  
Article
Decentralised Manufacturing as a Networked Cyber–Physical System: Formalising Free and Open-Source Software Governance and ML Adaptation for Distributed Robustness
by Bruno Dogančić, Jurica Rožić, Marko Jokić and Marko Čeredar
Systems 2026, 14(5), 469; https://doi.org/10.3390/systems14050469 (registering DOI) - 26 Apr 2026
Viewed by 47
Abstract
Decentralised manufacturing is expanding as digitally controlled fabrication tools become accessible to SMEs, independent operators, and community workshops outside traditional factory settings, but the resulting heterogeneous, autonomously operated network introduces systemic uncertainty that no central authority governs. This paper proposes a systems-theoretic framework [...] Read more.
Decentralised manufacturing is expanding as digitally controlled fabrication tools become accessible to SMEs, independent operators, and community workshops outside traditional factory settings, but the resulting heterogeneous, autonomously operated network introduces systemic uncertainty that no central authority governs. This paper proposes a systems-theoretic framework in which Free and Open-Source Software (FOSS) governance acts as the structural interoperability layer of a distributed cyber–physical manufacturing system (CPS), and node-local digital twins—each hosting a machine learning (ML) disturbance estimator—provide local adaptive compensation without centralised data aggregation. A defining property of the architecture is automatic improvement propagation: learned corrections distribute via federated learning to structurally similar nodes without operator intervention, and the open, observable FOSS ecosystem enables advances in one fabrication modality to transfer to others through shared interface standards. The framework is applied analytically to three disturbance classes: regulatory restriction, technical process variability, and supply chain disruption. Across cases, the analysis shows how open modular interfaces and local adaptation preserve functional continuity under perturbations that would more strongly affect centralised architectures. The contribution is a unified mathematical basis for robustness analysis in decentralised manufacturing CPS and a foundation for future simulation and empirical validation. Full article
21 pages, 401 KB  
Article
The Welfare of Refugee Children in Bulgarian Society in the Context of State Policies and Public Attitudes
by Albena Ilieva Nakova and Valentina Georgieva Milenkova
Societies 2026, 16(5), 141; https://doi.org/10.3390/soc16050141 - 24 Apr 2026
Viewed by 88
Abstract
In recent years, the escalation of international and internal conflicts in the Middle East and North Africa and Bulgaria’s geographical location, which places it on the route of those seeking protection from these regions in Europe, has led to a significant increase in [...] Read more.
In recent years, the escalation of international and internal conflicts in the Middle East and North Africa and Bulgaria’s geographical location, which places it on the route of those seeking protection from these regions in Europe, has led to a significant increase in the number of refugee children arriving in Bulgaria. According to Eurostat data, Bulgaria ranks fourth in terms of the number of unaccompanied refugee children in the European Union. In this article, the possibilities for achieving the welfare of refugee children and their successful integration into society are considered as a result of the intersection of two main trends—state legislation and public policies aimed at guaranteeing the best interests of refugee children, and public opinion about refugee children, which, in some cases, cause the failure of positive state measures and policies. The data on public attitudes towards refugee children used here are the result of an empirical study conducted in 2021 by the authors of this article. The results show that while state legislation and public policies are evolving towards ensuring the best interests of the child, the same cannot be said for public attitudes and the distance that the local population demonstrates towards refugee children. Full article
21 pages, 9621 KB  
Article
Insights into Spatial Heterogeneity of Land Subsidence Susceptibility Using InSAR and Explainable Machine Learning
by Min Shi, Xiaoyu Wang, Chenghong Gu, Mingliang Gao, Chaofan Zhou and Huili Gong
Remote Sens. 2026, 18(9), 1298; https://doi.org/10.3390/rs18091298 - 24 Apr 2026
Viewed by 108
Abstract
Land subsidence (LS) is a widespread geoenvironmental problem driven by both natural processes and human activities. Identifying the main factors controlling LS susceptibility and their spatial contribution patterns is essential for LS management and mitigation. In this study, an interpretable earth observation framework [...] Read more.
Land subsidence (LS) is a widespread geoenvironmental problem driven by both natural processes and human activities. Identifying the main factors controlling LS susceptibility and their spatial contribution patterns is essential for LS management and mitigation. In this study, an interpretable earth observation framework was developed for the North China Plain (NCP) to quantify both spatial and non-spatial contributions of dominant LS drivers. Land displacement was derived from Sentinel-1A SAR images using Multi-Temporal Interferometric Synthetic Aperture Radar (MT-InSAR) processing. The displacement map was then combined with nine geoenvironmental variables to construct an LS susceptibility model using the eXtreme Gradient-Boosting (XGBoost) algorithm. The model performed well, with an R2 of 0.96, an EVS of 0.96, and an MAE of 2.25 mm/yr. SHapley Additive exPlanations (SHAP) analysis was employed to quantify feature contributions and their effects on LS susceptibility. The results show that a deep groundwater level (DGL) was the dominant factor, followed by elevation and a shallow groundwater level (SGL). The effect of DGL was strongest when it ranged from −75 to 20 m. Elevation showed a clear effect on LS occurrence when values fall between 30 and 50 m. Relatively high subsidence sensitivity was mainly observed in areas where SGL was below −7 m. Interaction effects, particularly those between DGL and elevation and between DGL and SGL, further increased LS susceptibility in specific areas. The highest predicted susceptibility occurred in areas with DGL below −20 m and elevations below 30 m. Higher susceptibility was also identified where DGL was high and SGL ranged between −20 and −10 m, and where DGL was low and SGL ranged from 15 to 20 m. In contrast, factors such as slope and aspect had limited influence at the regional scale. The contributions of the predominant factors show obvious marginal effects and significant spatial heterogeneity to LS susceptibility. The results clarify where and how key factors shape subsidence and can inform targeted mitigation measures and urban planning by local authorities. Full article
24 pages, 4530 KB  
Article
A Crowdsourcing-Based Digital Storytelling Platform for Preserving Intangible Cultural Heritage: A Case Study of Southern Thai Textiles
by Supaporn Chai-Arayalert, Supattra Puttinaovarat and Wanida Saetang
Heritage 2026, 9(5), 160; https://doi.org/10.3390/heritage9050160 - 24 Apr 2026
Viewed by 175
Abstract
The preservation of tacit knowledge embedded in Southern Thai textiles remains a significant challenge because much of this knowledge is dispersed across private households and is inadequately supported by conventional object-centered documentation systems. This study developed a crowdsourcing-based digital storytelling platform that enabled [...] Read more.
The preservation of tacit knowledge embedded in Southern Thai textiles remains a significant challenge because much of this knowledge is dispersed across private households and is inadequately supported by conventional object-centered documentation systems. This study developed a crowdsourcing-based digital storytelling platform that enabled communities to document, organize, and disseminate knowledge related to Southern Thai textile heritage. The platform integrated community participation, structured narrative authoring, and knowledge organization within a socio-technical system designed for cultural heritage documentation. To guide its development, the study proposed the Crowdsourced-Storytelling Intangible Cultural Heritage Framework (CS-ICH Framework) and operationalizes it through requirements analysis, iterative prototyping, and empirical user evaluation. The evaluation results indicated high levels of user satisfaction and positive user perceptions regarding knowledge accessibility, content organization, and the platform’s support for heritage preservation. These findings suggested that participatory digital platforms can effectively facilitate the documentation and dissemination of locally embedded cultural knowledge that is difficult to capture through conventional institutional systems. This study contributed to digital heritage research by providing a potentially transferable framework and design principles for integrating crowdsourcing and digital storytelling within platforms designed to preserve and transmit intangible and community-held cultural heritage. Full article
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16 pages, 5250 KB  
Article
Benchmarking Multi-Platform APIs and Fuzzy-AHP for Enhanced HAZMAT Emergency Logistics: A Case Study of Bangkok’s Expressway Network
by Wipaporn Kitthiphovanonth, Chalermchai Chaikittiporn, Arroon Ketsakorn and Korn Puangnak
Logistics 2026, 10(5), 95; https://doi.org/10.3390/logistics10050095 - 24 Apr 2026
Viewed by 249
Abstract
Background: To address the critical challenges of hazardous material (HAZMAT) incidents in dense urban areas, this study develops a hybrid framework for spatial emergency response optimization tailored for Intelligent Transport Systems (ITSs). Methods: Our approach integrates the Fuzzy Analytic Hierarchy Process [...] Read more.
Background: To address the critical challenges of hazardous material (HAZMAT) incidents in dense urban areas, this study develops a hybrid framework for spatial emergency response optimization tailored for Intelligent Transport Systems (ITSs). Methods: Our approach integrates the Fuzzy Analytic Hierarchy Process (FAHP) with a rigorous technical benchmarking of multiple navigation APIs to improve routing decisions under volatile Bangkok traffic. By employing a normalized cost function (scale 0–1), we evaluated the performance of localized (Longdo Map) versus global (Google Maps and OpenStreetMap) platforms across day and night scenarios. Results: Experimental results, yielding normalized costs between 0.464 and 0.748, identified Bon Kai as the optimal response node, whereas Chan Road showed the lowest efficiency. Interestingly, OpenStreetMap provided the highest temporal consistency for emergency logistics. Conclusions: These findings offer a practical decision-support tool for authorities, proving that integrated API assessment is essential for building resilient and responsive urban mobility infrastructures. Full article
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24 pages, 11638 KB  
Article
Socio-Ecological Barriers to the Sustainable Management of the Andean Walnut (Juglans neotropica) and the Value Paradox in the Ecuadorian Andes: A Case Study from Imbabura Province, Ecuador
by Oscar Hernando Eraso Terán, Guillermo David Varela Jacome, Mario José Añazco Romero and Hugo Vinicio Vallejos Álvarez
Conservation 2026, 6(2), 52; https://doi.org/10.3390/conservation6020052 (registering DOI) - 24 Apr 2026
Viewed by 97
Abstract
The Andean walnut (Juglans neotropica Diels), locally known as tocte, is a keystone tree species of major socio-ecological importance in South American mountain ecosystems, facing severe anthropogenic pressure associated with genetic erosion, habitat fragmentation, and unregulated selective logging. This article presents a [...] Read more.
The Andean walnut (Juglans neotropica Diels), locally known as tocte, is a keystone tree species of major socio-ecological importance in South American mountain ecosystems, facing severe anthropogenic pressure associated with genetic erosion, habitat fragmentation, and unregulated selective logging. This article presents a case study applying a qualitative phenomenological approach to examine the power relations and institutional failures shaping the sustainable management of its value chain in Imbabura Province, Ecuador. Drawing on 21 in-depth semi-structured interviews with key actors (including woodcarvers, sawyers, traders, and environmental authorities) conducted between March and September 2025 until theoretical saturation was achieved, and supported by thematic analysis in ATLAS.ti, we identified five thematic categories revealing the tension between cultural valuation and market pressure. The findings confirm the existence of a value paradox, whereby high timber demand paradoxically accelerates resource depletion rather than incentivizing conservation, as premature harvesting of young trees undermines the viability of non-timber forest products such as nuts and accelerates the loss of local genetic resources. We conclude that the long-term conservation of the species requires a transition toward polycentric stewardship, community forestry enterprises, and integrated landscape management in which the standing tree is formally recognized as carrying greater ecological and economic value than harvested timber. Full article
(This article belongs to the Special Issue Forest Ecosystem Restoration)
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28 pages, 1572 KB  
Article
Assessment of Groundwater Quality in Some Regions of Kosovo Based on Physico-Chemical and Microbiological Parameters
by Florjana Zogaj, Tatjana Blazhevska, Fatbardh Sallaku, Rakesh Ranjan Thakur, Hazir Çadraku, Upaka Rathnayake, Debabrata Nandi, Vesna Knights, Gorica Pavlovska, Pajtim Bytyçi, Erinda Lika, Osman Fetoshi, Valentina Velkovski, Rozeta Hasalliu and Bojan Đurin
Limnol. Rev. 2026, 26(2), 16; https://doi.org/10.3390/limnolrev26020016 - 23 Apr 2026
Viewed by 183
Abstract
Physicochemical and microbiological parameters are important indicators of drinking water quality. This study assessed the quality of groundwater used for drinking in four regions of Kosovo at 16 locations using an integrated assessment framework that combined physicochemical, microbiological, and Water Quality Index (WQI) [...] Read more.
Physicochemical and microbiological parameters are important indicators of drinking water quality. This study assessed the quality of groundwater used for drinking in four regions of Kosovo at 16 locations using an integrated assessment framework that combined physicochemical, microbiological, and Water Quality Index (WQI) approaches. The results reveal substantial spatial variability in water quality. While most physicochemical parameters remained within recommended limits, elevated values of total dissolved solids (up to 2792.5 mg/L), electrical conductivity (up to 2768.5 µS/cm), nitrate (up to 60.75 mg/L), and phosphate (up to 0.875 mg/L) were observed at several locations, indicating localized hydrogeochemical and anthropogenic influences. Dissolved oxygen levels were generally low (0.68–5.49 mg/L), reflecting limited aeration conditions in groundwater systems. Microbiological analysis revealed critical contamination, with Escherichia coli concentrations up to 299.9 CFU/100 mL, and all sampling sites exceeded permissible limits, indicating widespread fecal pollution and rendering the groundwater unsafe for direct consumption. WQI assessment further confirmed this condition, where 93.75% of locations were classified as medium quality using the NSF-WQI method, whereas the WA-WQI method categorized 68.75% of samples as poor and 6.25% as very poor. The novelty of this study lies in the integrated evaluation of hydrogeochemical processes and microbiological contamination using dual WQI methods and multivariate statistical analysis, providing a comprehensive understanding of groundwater degradation pathways. The findings are significant for policymakers, environmental managers, and public health authorities, highlighting the urgent need for groundwater treatment, improved sanitation infrastructure, and sustainable water resource management strategies in vulnerable regions. Full article
(This article belongs to the Special Issue Freshwater Microbiology and Public Health)
18 pages, 1437 KB  
Project Report
From Tradition to Technology: A Framework for Smart Pilgrim Management on the Camino de Santiago
by Adriana Mar, Fernando Monteiro, Pedro Pereira, Jose Carlos García, João F. A. Martins and Daniel Basulto
Multimodal Technol. Interact. 2026, 10(5), 44; https://doi.org/10.3390/mti10050044 - 23 Apr 2026
Viewed by 184
Abstract
The Camino de Santiago, a UNESCO-listed pilgrimage route, has experienced sustained growth in visitor numbers, challenging municipalities to preserve cultural integrity while ensuring service quality. This study reviews people-counting technologies and proposes a smart pilgrim management framework grounded in flux measurement systems to [...] Read more.
The Camino de Santiago, a UNESCO-listed pilgrimage route, has experienced sustained growth in visitor numbers, challenging municipalities to preserve cultural integrity while ensuring service quality. This study reviews people-counting technologies and proposes a smart pilgrim management framework grounded in flux measurement systems to support data-driven and sustainable decision-making. Drawing on the smart tourism literature, the conceptual framework integrates infrared counters, mobile tracking solutions, and GPS/Wi-Fi data to generate real-time insights into pilgrim flows. A pilot simulation illustrates how these data can inform operational and strategic planning. The framework enables local authorities to monitor pedestrian movements, anticipate service demands (sanitation, accommodation, and safety), and detect overcrowding in sensitive heritage areas. By incorporating technological solutions into traditionally low-tech pilgrimage settings, municipalities can transition from reactive to proactive management approaches. The paper contributes a scalable and ethically grounded framework tailored to heritage pilgrimage routes, advancing smart tourism applications in culturally significant contexts. Full article
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14 pages, 3380 KB  
Proceeding Paper
A Rapid Stress Retrieval Approach for Long-Fiber Angle-Ply Laminates Using the RBF Kansa Method
by Andrea Chiappa and Corrado Groth
Eng. Proc. 2026, 131(1), 34; https://doi.org/10.3390/engproc2026131034 - 22 Apr 2026
Viewed by 114
Abstract
Building on a previous work presented by the authors, this study extends a fast stress retrieval method to long-fiber angle-ply laminates subjected to constant bending and torque moments. The fiber/matrix interface stress state is efficiently estimated using global deformation data obtained from a [...] Read more.
Building on a previous work presented by the authors, this study extends a fast stress retrieval method to long-fiber angle-ply laminates subjected to constant bending and torque moments. The fiber/matrix interface stress state is efficiently estimated using global deformation data obtained from a finite element analysis performed on a coarse model, potentially employing a homogenized material. Radial basis functions (RBFs) are utilized to bridge the macroscale and microscale, enabling the extraction of appropriate boundary conditions at the representative volume element (RVE) level. A collocation-based Kansa method, also leveraging RBF, is then applied to a carefully selected set of points to determine the local stress distribution. The accuracy of the proposed approach is assessed by comparing its results with high-fidelity FEM sub-modeling. Full article
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15 pages, 2375 KB  
Article
Piezoresistive Smart Bricks for Structural Health Monitoring of Masonry Arch Bridges: An Exploratory Numerical Study
by Andrea Meoni, Michele Mattiacci, Alina Elena Eva, Francesco Falini and Filippo Ubertini
Infrastructures 2026, 11(5), 144; https://doi.org/10.3390/infrastructures11050144 - 22 Apr 2026
Viewed by 236
Abstract
Masonry arch bridges are critical assets in aging transportation networks, yet their Structural Health Monitoring (SHM) remains challenging. Smart bricks—piezoresistive sensing units compatible with masonry structures and capable of acting simultaneously as load-bearing components and strain sensors—offer a promising solution for embedding self-sensing [...] Read more.
Masonry arch bridges are critical assets in aging transportation networks, yet their Structural Health Monitoring (SHM) remains challenging. Smart bricks—piezoresistive sensing units compatible with masonry structures and capable of acting simultaneously as load-bearing components and strain sensors—offer a promising solution for embedding self-sensing capability directly within the masonry. While previous work by the authors has investigated their use in masonry walls, their application to arched structures remains unexplored. This gap is particularly significant given that arches, characterized by a predominantly compressive stress state, represent a natural context for smart-brick implementation. This study presents a numerical investigation assessing the potential of smart bricks for strain-based SHM of masonry arch bridges. A Finite Element (FE) model, derived from a validated experimental benchmark representative of typical Italian railway arch bridges, was used to virtually embed smart bricks at selected cross-sections along the arch. Damage progression was simulated through cyclic loading–unloading stages, enabling direct correlation between strain evolution and structural deterioration. Results demonstrate that smart bricks accurately capture damage-driven strain redistributions, closely mirroring both the sequence of damage formation and the associated collapse mechanism. These findings support the use of smart bricks for early detection of localized structural changes in masonry arches, providing a foundation for future experimental validation and real-world deployment of minimally invasive SHM systems. Full article
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17 pages, 1986 KB  
Article
Next-Generation Sequencing Strategies During the 2024–2025 Avian Influenza A(H5N1) Emergency Response in the U.S
by Julia C. Frederick, Kristine A. Lacek, Matthew J. Wersebe, Bo Shu, Lisa M. Keong, Juliana DaSilva, Malania M. Wilson, Sydney R. Sheffield, Jimma Liddell, Natasha Burnett, Reina Chau, Amanda H. Sullivan, Yunho Jang, Juan A. De La Cruz, Elizabeth A. Pusch, Dan Cui, Yasuko Hatta, Sabrina Schatzman, Norman Hassell, Xiao-Yu Zheng, Ha T. Nguyen, Larisa Gubareva, Rebecca Kondor, Han Di, Vivien G. Dugan, Charles T. Davis, Benjamin L. Rambo-Martin and Marie K. Kirbyadd Show full author list remove Hide full author list
Viruses 2026, 18(4), 482; https://doi.org/10.3390/v18040482 - 21 Apr 2026
Viewed by 441
Abstract
The first influenza A(H5N1) human case associated with the A(H5N1) dairy cattle outbreak in the United States was identified in April 2024. The U.S. CDC response to this outbreak was activated days later and remained active until July 2025. During this time, 70 [...] Read more.
The first influenza A(H5N1) human case associated with the A(H5N1) dairy cattle outbreak in the United States was identified in April 2024. The U.S. CDC response to this outbreak was activated days later and remained active until July 2025. During this time, 70 human cases of influenza A(H5N1) were detected with a range of epidemiological links to sources of exposure. Next-generation sequencing (NGS) of human samples was an effectual mechanism for tracking and analyzing the outbreak evolution throughout the response. Due to the specimens’ importance and their variable physical quality, an assortment of laboratory methods was utilized including influenza segment-specific amplification, enrichment capture, short-read, and long-read sequencing. Combining these methods allowed for high-quality genomic data production with rapid turnaround times—typically 2 days from sample receipt to public database submission. By leveraging replicate sequencing, enrichment capture, and sequencing of diagnostic amplicons, valuable genomic data could be produced directly from human clinical specimens that would have normally been considered too weak for routine virologic surveillance sequencing. The resulting assemblies were characterized and analyzed by CDC and shared with local and state public health authorities to facilitate case investigations and risk assessment. These data were further used for phylogenetic analyses of viruses from human cases to investigate likely animal-to-human transmission events and identify clusters within the outbreak that might indicate trends in the types of exposures. Through the adaptable laboratory workflow and the rapid release of viral genomic data, the public health risk mitigation strategies could be evaluated and adjusted in real time. Full article
(This article belongs to the Special Issue H5N1 Influenza Viruses)
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20 pages, 1144 KB  
Article
The University of Salerno’s Model for Seasonal Influenza Vaccinations in the Workplace
by Francesco De Caro, Nadia Pecoraro, Francesca Malatesta, Simona Caruccio, Federico Della Rocca, Alessandra Mea, Matteo Tomeo, Raffaele De Caro, Giuseppina Cersosimo, Arcangelo Saggese Tozzi, Anna Luisa Caiazzo, Giovanni Boccia, Emanuela Santoro, Mario Capunzo and Giuseppina Moccia
Vaccines 2026, 14(4), 359; https://doi.org/10.3390/vaccines14040359 - 17 Apr 2026
Viewed by 319
Abstract
Background: During the flu season, there is an increase in absenteeism due to illness, a drop in productivity, and a greater risk of the virus spreading among workers. Thus, the Italian Ministry of Health recommends vaccination for essential service workers. The University [...] Read more.
Background: During the flu season, there is an increase in absenteeism due to illness, a drop in productivity, and a greater risk of the virus spreading among workers. Thus, the Italian Ministry of Health recommends vaccination for essential service workers. The University of Salerno, in collaboration with the local health authority of Salerno, offers free vaccination to its employees. Methods: A public health methodology for seasonal influenza vaccination in the workplace is presented—specifically in the university setting—with the aim of identifying individual, contextual, and organizational elements of the model that have promoted vaccination uptake. An ad hoc questionnaire was used (October–December 2025) to survey 399 academic employees, investigating seasonal influenza vaccination in the following aspects: recent personal experiences, motivations, vaccination experiences at university, sources of information, considerations regarding national and local vaccination campaigns, and level of vaccine confidence (VCI). Results: Seasonal influenza vaccination at the University is appreciated for its compatibility with working hours (66.1%), the availability of a platform that allows flexible booking (56.9%), the perception of safety in the environment (31.6%), the fact that the vaccine is free (17.4%), and the involvement of office/laboratory colleagues (5%). Participants appreciate the model and would apply it to other vaccinations at the University and in other institutional settings. A significant relationship (F = 7.24; df = 1; p < 0.05) exists between confidence in the vaccine and the sense of security experienced when receiving the vaccine in the workplace. Data analysis was performed using the IBM SPSS v.28 software. Conclusions: The model proposed can be applied to other institutional contexts, simplifying and facilitating access to vaccines by implementing vaccination campaigns tailored to specific work environments. Full article
(This article belongs to the Section Vaccines and Public Health)
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15 pages, 1828 KB  
Article
Assessing Mass Screening as an Effective Tool for Pandemic Management: An Experimental Study of SARS-CoV-2 Diagnosis
by Adil Lagmar, Maryem Wardi, Ahmed Belmouden, Mohamed Aghrouch and Zohra Lemkhente
Pandemics 2026, 1(1), 5; https://doi.org/10.3390/pandemics1010005 - 17 Apr 2026
Viewed by 136
Abstract
SARS-CoV-2 infection has emerged worldwide. To reduce the number of cases and limit the transmission of the virus, health and local authorities have implemented several strategies. Mass screening is a key strategy for mitigating the damage caused by this pandemic. This strategy is [...] Read more.
SARS-CoV-2 infection has emerged worldwide. To reduce the number of cases and limit the transmission of the virus, health and local authorities have implemented several strategies. Mass screening is a key strategy for mitigating the damage caused by this pandemic. This strategy is based on the use of qRT-PCR and pooling to diagnose SARS-CoV-2 infection. The present work explores the performance and limitations of this strategy for the molecular diagnosis of SARS-CoV-2 infection. Three important technical aspects were retained: the comparison of two commercial extraction kits (BIGFISH and BIOER), the simulation of a non-compliant nasopharyngeal swab, and the evaluation of the pooling strategy. A total of 97 SARS-CoV-2-positive nasopharyngeal samples were used. The comparison of the two extraction kits was based on threshold cycles (Ct) values. The results showed a significant difference (IC = 95%) in the Ct of the nucleocapsid gene (N; p = 0.0000384) and RNA-dependent RNA polymerase (RdRp; p = 0.0254). However, no significant difference was observed between the Internal Control gene (IC; p = 0.0723) and Envelope gene (E; p = 0.150). The Ct values resulting from the BIGFISH extraction kit were generally lower than those obtained from BIOER. In terms of sensitivity, the RT-qPCR technique allows for the detection of viral RNA up to 10−3 as a dilution factor. This study demonstrated that the pooling strategy is an effective diagnostic technique. Positive samples remained detectable even in pools of 1000 or even 10,000 samples. However, the size of the pool under diagnostic conditions should not exceed a limit that must be dynamically adapted to prevalence to ensure economic and analytical viability. Full article
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22 pages, 2923 KB  
Article
Local Sanctuaries and Kin-Based Cults in Early Iron Age Judah: Evidence from Lachish
by Itamar Weissbein and Yosef Garfinkel
Religions 2026, 17(4), 487; https://doi.org/10.3390/rel17040487 - 16 Apr 2026
Viewed by 350
Abstract
This article presents a newly excavated Iron Age IIA cult room from Tel Lachish (Sanctuary BBE4) and examines its significance for the study of the organization of religious practice, situating this case within the broader corpus of Iron Age I–IIA local sanctuaries in [...] Read more.
This article presents a newly excavated Iron Age IIA cult room from Tel Lachish (Sanctuary BBE4) and examines its significance for the study of the organization of religious practice, situating this case within the broader corpus of Iron Age I–IIA local sanctuaries in Judah and the southern Levant. The evidence suggests that early Iron Age ritual practice was organized primarily at the level of extended kin groups, materialized in modest intramural cult rooms embedded within residential neighborhoods. These spaces reflect decentralized forms of religious authority, contrasting with the temple-centered ritual systems of the Bronze Age and with the increasing centralization of cult and religious authority in later phases of the Iron Age. By situating the Lachish evidence within a broader diachronic and regional framework, the study explores changing relationships between household ritual practices, kin-based social organization, and the development of state-level religious institutions in early Judah. Full article
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11 pages, 899 KB  
Article
Pediatric Out-of-Hospital Cardiac Arrest in a Physician-Staffed EMS System: A 13-Year Retrospective Descriptive Study from Southern Italy
by Luca Gregorio Giaccari, Gaetano Tammaro, Nicola D’Angelo, Daniele Antonaci, Eva Epifani, Luciana Mascia, Maria Caterina Pace, Vincenzo Pota and Pasquale Sansone
J. Cardiovasc. Dev. Dis. 2026, 13(4), 170; https://doi.org/10.3390/jcdd13040170 - 16 Apr 2026
Viewed by 334
Abstract
Background: Pediatric out-of-hospital cardiac arrest (OHCA) is rare and associated with poor outcomes. Evidence from physician-staffed EMS systems remains limited. This study aimed to describe the incidence, presenting rhythms, EMS response intervals, and outcomes of pediatric OHCA, and to describe incidence, presenting rhythms, [...] Read more.
Background: Pediatric out-of-hospital cardiac arrest (OHCA) is rare and associated with poor outcomes. Evidence from physician-staffed EMS systems remains limited. This study aimed to describe the incidence, presenting rhythms, EMS response intervals, and outcomes of pediatric OHCA, and to describe incidence, presenting rhythms, EMS response intervals, and prehospital outcomes in a local physician-staffed EMS system. Methods: We conducted a retrospective study of all pediatric (0–17 years) OHCA cases managed by the ASL Lecce physician-staffed EMS (southern Italy) between 2013 and 2025. Data were abstracted from standardized records. Variables included demographics, initial rhythm, EMS response intervals, temporal patterns, and return of spontaneous circulation (ROSC). The primary outcome was ROSC during prehospital care. Results: Twenty-seven cases were identified, corresponding to a cumulative incidence of 22.9 per 100,000 children over the study period (annualized incidence 1.73 per 100,000 children-year). Mean age was 11.9 ± 5.5 years (median 15); 59% were male. Initial rhythms were asystole in 81% and ventricular fibrillation (VF) in 19%; no pulseless ventricular tachycardia (pVT) or pulseless electrical activity (PEA) were recorded. Five patients had shockable rhythms, with seven shocks delivered overall. Mean time intervals were: event-to-call 1.0 ± 0.6 min, call-to-arrival 10.3 ± 4.1 min, event-to-arrival 11.3 ± 4.4 min. Arrests clustered during daytime (63%) and summer (41%). ROSC occurred in three patients (11%), two with VF and one with asystole; all arrests with ROSC were daytime events. In descriptive comparisons, ROSC cases showed a shorter call-to-arrival interval (T1–T2), whereas no consistent pattern was observed across all prehospital time intervals. Conclusions: Pediatric OHCA in this Italian physician-staffed EMS was infrequent, usually presented with asystole, and rarely achieved ROSC. Shockable rhythms were associated with better outcomes. Given the small sample size, findings related to response times should be interpreted with caution. System preparedness should include pediatric-specific training, early defibrillation access, and multicenter registries to improve care and track outcomes. Full article
(This article belongs to the Section Pediatric Cardiology and Congenital Heart Disease)
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