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5,261 Results Found

  • Review
  • Open Access
4 Citations
11,178 Views
33 Pages

4 July 2025

Research on smartphone lifespan is of high interest nowadays due to the growing number of smartphone users and the environmental impact associated with device turnover. Although the concept of smartphone lifespan varies in the literature, research de...

  • Article
  • Open Access
4 Citations
8,327 Views
16 Pages

Estimation of the Lifespan of Imported Passenger Vehicles in Mongolia

  • Tulga Mendjargal,
  • Eiji Yamasue and
  • Hiroki Tanikawa

6 November 2022

In the last few decades, there has been an increase in second-hand imported vehicles in developing countries, including Mongolia. However, the extension of vehicle lifespans abroad promotes circular economy activities. In this study, we investigated...

  • Article
  • Open Access
888 Views
33 Pages

Distribution Analysis of the Lifespan Trait in Drosophila

  • Camila A. Yumuhova,
  • Alexander V. Konopatov,
  • Alexander A. Shtil and
  • Oleg V. Bylino

12 December 2025

Research into longevity and aging involves comparing the size of cohorts at certain points on survival curves. However, this analysis is oversimplified because it provides limited information about the sample structure and the distribution of lifespa...

  • Article
  • Open Access
567 Views
12 Pages

4-Galactosylkojibiose Extends the Lifespan of Drosophila melanogaster

  • Haruki Kato,
  • Akari Hara,
  • Rinka Ota,
  • Riho Kobayashi,
  • Ryo Miyake,
  • Rabia Garibağaoğlu,
  • Jun Tomita,
  • Misato Tsuboi,
  • Chisato Oba and
  • Kazuhiko Kume
  • + 1 author

12 February 2026

Background/Objectives: Oligosaccharides, such as fructooligosaccharides (FOS), have long been used to promote human health due to their beneficial effects on the intestinal environment and their anti-inflammatory properties. Recent advances in manufa...

  • Review
  • Open Access
6 Citations
5,143 Views
36 Pages

Genetic, Environmental, and Stochastic Components of Lifespan Variability: The Drosophila Paradigm

  • Oleg V. Bylino,
  • Anna A. Ogienko,
  • Mikhail A. Batin,
  • Pavel G. Georgiev and
  • Evgeniya S. Omelina

Lifespan is a complex quantitative trait involving genetic and non-genetic factors as well as the peculiarities of ontogenesis. As with all quantitative traits, lifespan shows considerable variation within populations and between individuals. Drosoph...

  • Review
  • Open Access
774 Views
31 Pages

Yeast Chronological Lifespan Model as a Tool for Screening Aging Interventions

  • Pingkang Xu,
  • Xinyu Zhang,
  • Yuanxia Wang,
  • Sajid Ur Rahman,
  • Dejian Huang and
  • Ziyun Wu

Saccharomyces cerevisiae is a useful model to understand the biochemistry and biology of aging. Yeast speeds up the aging study due to its short lifespan, well-established genetics, and simple measurement for lifespan. The chronological lifespan in y...

  • Article
  • Open Access
5 Citations
2,327 Views
14 Pages

19 July 2024

We proposed a novel method for predicting the service life of optical cables based on the Autoformer model combined with the calculation method. Leveraging historical weather data from Guangzhou and employing specific cable length calculation techniq...

  • Review
  • Open Access
33 Citations
7,313 Views
13 Pages

Genetic Regulation of Physiological Reproductive Lifespan and Female Fertility

  • Isabelle M. McGrath,
  • Sally Mortlock and
  • Grant W. Montgomery

There is substantial genetic variation for common traits associated with reproductive lifespan and for common diseases influencing female fertility. Progress in high-throughput sequencing and genome-wide association studies (GWAS) have transformed ou...

  • Article
  • Open Access
5 Citations
4,350 Views
11 Pages

Decreased CRRT Filter Lifespan in COVID-19 ICU Patients

  • David Legouis,
  • Maria F. Montalbano,
  • Nils Siegenthaler,
  • Camille Thieffry,
  • Benjamin Assouline,
  • Pierre Emmanuel Marti,
  • Sebastian D. Sgardello,
  • Claudio Andreetta,
  • Céline Binvignat and
  • Frédéric Sangla
  • + 2 authors

26 April 2021

(1) Background: Increased thromboembolic events and an increased need for continuous renal replacement therapy (CRRT) have been frequently reported in COVID-19 patients. Our aim was to investigate CRRT filter lifespan in intensive care unit (ICU) COV...

  • Perspective
  • Open Access
13 Citations
4,391 Views
19 Pages

7 September 2023

With the growing interest in smart home environments and in providing seamless interactions with various smart devices, robust and reliable human activity recognition (HAR) systems are becoming essential. Such systems provide automated assistance to...

  • Review
  • Open Access
31 Citations
15,102 Views
23 Pages

Mental Sleep Activity and Disturbing Dreams in the Lifespan

  • Serena Scarpelli,
  • Chiara Bartolacci,
  • Aurora D’Atri,
  • Maurizio Gorgoni and
  • Luigi De Gennaro

Sleep significantly changes across the lifespan, and several studies underline its crucial role in cognitive functioning. Similarly, mental activity during sleep tends to covary with age. This review aims to analyze the characteristics of dreaming an...

  • Review
  • Open Access
29 Citations
9,068 Views
23 Pages

Effects of High Dietary Carbohydrate and Lipid Intake on the Lifespan of C. elegans

  • Berenice Franco-Juárez,
  • Saúl Gómez-Manzo,
  • Beatriz Hernández-Ochoa,
  • Noemi Cárdenas-Rodríguez,
  • Roberto Arreguin-Espinosa,
  • Verónica Pérez de la Cruz and
  • Daniel Ortega-Cuellar

8 September 2021

Health and lifespan are influenced by dietary nutrients, whose balance is dependent on the supply or demand of each organism. Many studies have shown that an increased carbohydrate–lipid intake plays a critical role in metabolic dysregulation, which...

  • Article
  • Open Access
124 Citations
15,013 Views
20 Pages

Myricetin-Mediated Lifespan Extension in Caenorhabditis elegans Is Modulated by DAF-16

  • Christian Büchter,
  • Daniela Ackermann,
  • Susannah Havermann,
  • Sebastian Honnen,
  • Yvonni Chovolou,
  • Gerhard Fritz,
  • Andreas Kampkötter and
  • Wim Wätjen

4 June 2013

Myricetin is a naturally occurring flavonol found in many plant based food sources. It increases the lifespan of Caenorhabditis elegans, but the molecular mechanisms are not yet fully understood. We have investigated the impact of this flavonoid on t...

  • Article
  • Open Access
5 Citations
4,910 Views
14 Pages

Soft-Shelled Turtle Peptides Extend Lifespan and Healthspan in Drosophila

  • Qianqian Wang,
  • Junhui Zhang,
  • Jiachen Zhuang,
  • Fei Shen,
  • Minjie Zhao,
  • Juan Du,
  • Peng Yu,
  • Hao Zhong and
  • Fengqin Feng

7 December 2022

In traditional Chinese medicine, soft-shelled turtle protein and peptides serve as a nutraceutical for prolonging the lifespan. However, their effects on anti-aging have not been clarified scientifically in vivo. This study aimed to determine whether...

  • Article
  • Open Access
7 Citations
8,356 Views
14 Pages

Young and Undamaged rMSA Improves the Healthspan and Lifespan of Mice

  • Jiaze Tang,
  • Anji Ju,
  • Boya Li,
  • Shaosen Zhang,
  • Yuanchao Gong,
  • Boyuan Ma,
  • Yi Jiang,
  • Hongyi Liu,
  • Yan Fu and
  • Yongzhang Luo

12 August 2021

Improvement of longevity is an eternal dream of human beings. The accumulation of protein damages is considered as a major cause of aging. Here, we report that the injection of exogenous recombinant mouse serum albumin (rMSA) reduced the total damage...

  • Brief Report
  • Open Access
4 Citations
2,642 Views
10 Pages

Reproductive Cessation and Post-Reproductive Lifespan in Honeybee Workers

  • Karolina Kuszewska,
  • Anna Woloszczuk and
  • Michal Woyciechowski

24 April 2024

The post-reproductive lifespan is an evolutionary enigma because the cessation of reproduction in animals seems contrary to the maximization of Darwinian fitness. Several theories aim to explain the evolution of menopause, one of which suggests that...

  • Article
  • Open Access
81 Citations
20,486 Views
14 Pages

Research on cyberbullying amongst students has tended to be conducted separately within specific education institutional contexts, schools, further education (FE) and higher education (HE), neglecting a view that takes account of the entire education...

  • Review
  • Open Access
31 Citations
10,009 Views
16 Pages

23 May 2022

S. cerevisiae plays a pivotal role as a model system in understanding the biochemistry and molecular biology of mammals including humans. A considerable portion of our knowledge on the genes and pathways involved in cellular growth, resistance to tox...

  • Review
  • Open Access
11 Citations
6,012 Views
10 Pages

22 June 2022

Mycoprotein is a filamentous fungal protein that was first identified in the 1960s. A growing number of publications have investigated inter-relationships between mycoprotein intakes and aspects of human health. A narrative review was undertaken focu...

  • Article
  • Open Access
59 Citations
5,053 Views
15 Pages

Study of the Effect of Neutral Polysaccharides from Rehmannia glutinosa on Lifespan of Caenorhabditis elegans

  • Yanyan Yuan,
  • Nianxin Kang,
  • Qingxia Li,
  • Yali Zhang,
  • Yonggang Liu and
  • Peng Tan

15 December 2019

The problem of an aging society is becoming increasingly acute. Diseases related to aging also come with it. There are some diseases that people can’t treat fundamentally. Therefore, people try to find a natural ingredient from natural medicine...

  • Article
  • Open Access
28 Citations
3,947 Views
13 Pages

Polygonati Rhizoma Polysaccharide Prolongs Lifespan and Healthspan in Caenorhabditis elegans

  • Yage Luan,
  • Yu Jiang,
  • Rong Huang,
  • Xuan Wang,
  • Xiujuan He,
  • Yonggang Liu and
  • Peng Tan

27 February 2023

Polygonati Rhizoma is the dried rhizome of Polygonatum kingianum coll.et hemsl., Polygonatum sibiricum Red. or Polygonatum cyrtonema Hua, and has a long history of medication. Raw Polygonati Rhizoma (RPR) numbs the tongue and stings the throat, while...

  • Article
  • Open Access
42 Citations
8,283 Views
19 Pages

Influence of Diets with Varying Essential/Nonessential Amino Acid Ratios on Mouse Lifespan

  • Claudia Romano,
  • Giovanni Corsetti,
  • Vincenzo Flati,
  • Evasio Pasini,
  • Anna Picca,
  • Riccardo Calvani,
  • Emanuele Marzetti and
  • Francesco Saverio Dioguardi

18 June 2019

An adequate intake of essential (EAA) and non-essential amino acids (NEAA) is crucial to preserve cell integrity and whole-body metabolism. EAA introduced with diet may be insufficient to meet the organismal needs, especially under increased physiolo...

  • Article
  • Open Access
865 Views
17 Pages

Research on Lifespan Prediction Methods Using Ultrasonic Microimaging for Electronic Packaging

  • Haotian Wang,
  • Hongwei Ma,
  • Guangming Zhang,
  • Yuan Chen and
  • Ming Dong

17 March 2025

Addressing the issue of lifespan prediction for electronic packages under thermal loading, this paper proposes a method for predicting the lifespan of electronic packages based on ultrasonic microimaging. Firstly, experimental samples equipped with f...

  • Article
  • Open Access
1 Citations
2,435 Views
15 Pages

31 December 2023

Despite the technological achievements of unmanned aerial vehicles (UAVs) growing in academia and industry, there is a lack of studies on the storage devices in UAVs. However, this is an important aspect because the storage devices in UAVs have a lim...

  • Article
  • Open Access
654 Views
10 Pages

Multi-Model Longevity Assays Reveal Lifespan- and Healthspan-Promoting Effects of Bacillus subtilis WTC019

  • Nan Zheng,
  • Zhanlei Fan,
  • Yangzhou Diao,
  • Xiangyu Li,
  • Yan Zhang,
  • Bohui Shi,
  • Jinshan Li and
  • Shouyong Ju

Bacillus subtilis is a spore-forming probiotic with an established safety profile, yet its effects on aging-related phenotypes remain incompletely defined. Here, we assessed the lifespan- and healthspan-promoting activity of a novel strain, B. subtil...

  • Article
  • Open Access
7 Citations
3,946 Views
13 Pages

Curcumin Inhibits TORC1 and Prolongs the Lifespan of Cells with Mitochondrial Dysfunction

  • Arshia Naaz,
  • Yizhong Zhang,
  • Nashrul Afiq Faidzinn,
  • Sonia Yogasundaram,
  • Rajkumar Dorajoo and
  • Mohammad Alfatah

1 September 2024

Aging is an inevitable biological process that contributes to the onset of age-related diseases, often as a result of mitochondrial dysfunction. Understanding the mechanisms behind aging is crucial for developing therapeutic interventions. This study...

  • Article
  • Open Access
47 Citations
6,040 Views
20 Pages

Effect of Essential Nutrients on Roots Growth and Lifespan of Huanglongbing Affected Citrus Trees

  • Alisheikh A. Atta,
  • Kelly T. Morgan,
  • Said A. Hamido and
  • Davie M. Kadyampakeni

9 April 2020

Understanding citrus tree root development and dynamics are critical in determining crop best nutrient management practices. The role of calcium (Ca) and magnesium (Mg), manganese (Mn), Zinc (Zn), and boron (B) on huanglongbing (HLB) affected citrus...

  • Article
  • Open Access
1,171 Views
13 Pages

13 May 2025

This study specifically examines the post-reproductive lifespan and ovarian activation in honeybee workers (Apis mellifera) with differing life expectancies. Drawing on the “grandmother hypothesis”, which postulates that older females enh...

  • Article
  • Open Access
2 Citations
4,004 Views
20 Pages

11 September 2024

In order to extend the lifespan of SSDs, it is essential to achieve wear leveling that evenly distributes the accumulated erase counts of NAND blocks, thereby delaying the occurrence of bad blocks as much as possible. This paper proposes the Greedy-M...

  • Review
  • Open Access
25 Citations
18,771 Views
34 Pages

20 February 2017

The windings insulation of electrical machines will remain a topic that is updated frequently. The criteria severity requested by the electrical machine applications increases continuously. Manufacturers and designers are always confronted with new r...

  • Article
  • Open Access
4 Citations
5,031 Views
14 Pages

L-Theanine Extends the Lifespan of Caenorhabditis elegans by Reducing the End Products of Advanced Glycosylation

  • Zhihang Huang,
  • Haiming Jing,
  • Yan Pan,
  • Hongxia Cai,
  • Wenjing Zhang,
  • Jingyuan Zhu,
  • Nan Zhang,
  • Dan Wu,
  • Wentao Xu and
  • Shan Gao
  • + 5 authors

13 January 2025

L-theanine, a non-protein amino acid naturally occurring in tea leaves, is recognized for its antioxidant, anti-inflammatory, and neuroprotective properties. Despite its known benefits, the mechanisms by which L-theanine influences lifespan extension...

  • Article
  • Open Access
14 Citations
4,278 Views
18 Pages

Dynamic Changes of Brain Cilia Transcriptomes across the Human Lifespan

  • Siwei Chen,
  • Wedad Alhassen,
  • Roudabeh Vakil Monfared,
  • Benjamin Vachirakorntong,
  • Surya M. Nauli,
  • Pierre Baldi and
  • Amal Alachkar

27 September 2021

Almost all brain cells contain primary cilia, antennae-like microtubule sensory organelles, on their surface, which play critical roles in brain functions. During neurodevelopmental stages, cilia are essential for brain formation and maturation. In t...

  • Article
  • Open Access
40 Citations
8,456 Views
13 Pages

Clostridium butyricum MIYAIRI 588 Increases the Lifespan and Multiple-Stress Resistance of Caenorhabditis elegans

  • Maiko Kato,
  • Yumi Hamazaki,
  • Simo Sun,
  • Yoshikazu Nishikawa and
  • Eriko Kage-Nakadai

5 December 2018

Clostridium butyricum MIYAIRI 588 (CBM 588), one of the probiotic bacterial strains used for humans and domestic animals, has been reported to exert a variety of beneficial health effects. The effect of this probiotic on lifespan, however, is unknown...

  • Review
  • Open Access
134 Citations
28,869 Views
24 Pages

Mechanisms of Lifespan Regulation by Calorie Restriction and Intermittent Fasting in Model Organisms

  • Dae-Sung Hwangbo,
  • Hye-Yeon Lee,
  • Leen Suleiman Abozaid and
  • Kyung-Jin Min

24 April 2020

Genetic and pharmacological interventions have successfully extended healthspan and lifespan in animals, but their genetic interventions are not appropriate options for human applications and pharmacological intervention needs more solid clinical evi...

  • Article
  • Open Access
686 Views
15 Pages

Comparative Mechanisms of Different Bifidobacteria in Combating Pathogen Infection and Prolonging the Lifespan in Caenorhabditis elegans

  • Xueer Wang,
  • Shixiang Wu,
  • Wen Zhao,
  • Zhaozhong Zeng,
  • Jian He,
  • Hanglian Lan,
  • Bing Fang,
  • Haina Gao,
  • Yue Liu and
  • Ming Zhang
  • + 2 authors

The research employed Caenorhabditis elegans to compare the anti-infection and lifespan-extending properties of Bifidobacterium. The results demonstrated that BL-99 and YLGB-1496 intervention improved the nematodes’ resistance to Staphylococcus...

  • Article
  • Open Access
6 Citations
3,749 Views
18 Pages

Nutritional Programming of the Lifespan of Male Drosophila by Activating FOXO on Larval Low-Nutrient Diet

  • Yue Gao,
  • Xingyi Cheng,
  • Yao Tian,
  • Zhixiao Yuan,
  • Xiaolan Fan,
  • Deying Yang and
  • Mingyao Yang

11 April 2023

Nutrition during the developmental stages has long-term effects on adult physiology, disease and lifespan, and is termed nutritional programming. However, the underlying molecular mechanisms of nutritional programming are not yet well understood. In...

  • Feature Paper
  • Article
  • Open Access
4 Citations
2,383 Views
27 Pages

19 September 2023

Slowing down replacement cycles to reduce resource depletion and prevent waste generation is a promising path toward a circular economy (CE). However, an obligation to longevity only sometimes makes sense. It could sometimes even backfire if one focu...

  • Article
  • Open Access
2 Citations
2,723 Views
14 Pages

To provide a theoretical basis for biogenic fly-killing pesticides, in this study, we sought to examine the lethal effects of Lepista nuda mycelium-supplemented diets in Drosophila melanogaster. In doing so, we also studied the effects of Lepista nud...

  • Article
  • Open Access
25 Citations
6,980 Views
14 Pages

Iron Supplementation Delays Aging and Extends Cellular Lifespan through Potentiation of Mitochondrial Function

  • Jovian Lin Jing,
  • Trishia Cheng Yi Ning,
  • Federica Natali,
  • Frank Eisenhaber and
  • Mohammad Alfatah

2 March 2022

Aging is the greatest challenge to humankind worldwide. Aging is associated with a progressive loss of physiological integrity due to a decline in cellular metabolism and functions. Such metabolic changes lead to age-related diseases, thereby comprom...

  • Communication
  • Open Access
2 Citations
2,746 Views
10 Pages

3D Media Stabilizes Membrane and Prolongs Lifespan of Defolliculated Xenopus laevis Oocytes

  • Nikhil D. Aggarwal,
  • Steven L. Zeng,
  • Ryan J. Lashgari,
  • Leland C. Sudlow and
  • Mikhail Y. Berezin

Xenopus laevis oocytes are commonly used in many fundamental biological studies. One of the major limitations of X. laevis oocytes is their short storage lifespan with most defolliculated oocytes physically deteriorating in 10 days or less. Herein, w...

  • Article
  • Open Access
8 Citations
4,450 Views
13 Pages

30 August 2020

Our desire to live longer has led to an ever-increasing number of novel antiaging products. However, few molecules have any real effect and new ones need to be studied before they can be used commercially. In this contribution, activation of the calo...

  • Review
  • Open Access
26 Citations
13,731 Views
12 Pages

24 April 2014

A marked increase in the frequency of obesity at the population level has resulted in an increasing number of obese women entering pregnancy. The increasing realization of the importance of the fetal environment in relation to chronic disease across...

  • Article
  • Open Access
13 Citations
5,814 Views
12 Pages

Aggressiveness, Mating Behaviour and Lifespan of Group Housed Rabbit Does

  • Zsolt Gerencsér,
  • Zsolt Matics,
  • Rubina T. Szabó,
  • Károly Kustos,
  • Annamária Mikó,
  • István Nagy,
  • Meinrad Odermatt,
  • Tamás Atkári and
  • Zsolt Szendrő

20 September 2019

Aggressiveness is one of the main problems in group housing of rabbit does. The aim of the experiment was to investigate the frequency of aggressiveness and mating behaviour as well as the lifespan of does depending on group composition. The female a...

  • Article
  • Open Access
1 Citations
1,628 Views
8 Pages

Influence of Inflammation on Red Blood Cell Lifespan in Peritoneal Dialysis Patients

  • Huiping Zhao,
  • Yuchao Zhao,
  • Bei Wu,
  • Li Bai,
  • Lixia Lu and
  • Li Zuo

24 November 2024

Background and hypothesis: Renal anemia is linked to a decreased lifespan of red blood cells. The factors influencing red blood cell lifespan (RBCLS) in peritoneal dialysis patients, particularly the connection between inflammation and RBCLS, are sti...

  • Article
  • Open Access
15 Citations
4,813 Views
14 Pages

5 November 2019

In animals, dietary restriction or suppression of genes involved in nutrient sensing tends to increase lifespan. In contrast, food restriction in honeybees (Apis mellifera) shortens lifespan by accelerating a behavioural maturation program that culmi...

  • Article
  • Open Access
349 Views
27 Pages

31 December 2025

A comprehensive assessment of photovoltaic (PV) enhancement technologies requires a metric that incorporates not only performance gains but also economic viability and system compatibility. This paper introduces the Lifespan-, Surface-area-, and Cost...

  • Article
  • Open Access
94 Citations
37,488 Views
24 Pages

20 June 2008

The first and second laws of thermodynamics were applied to biochemical reactions typical of human metabolism. An open-system model was used for a human body. Energy conservation, availability and entropy balances were performed to obtain the entropy...

  • Article
  • Open Access
1 Citations
2,906 Views
24 Pages

The Effect of the Tau Protein on D. melanogaster Lifespan Depends on GSK3 Expression and Sex

  • Ekaterina R. Veselkina,
  • Mikhail V. Trostnikov,
  • Natalia V. Roshina and
  • Elena G. Pasyukova

21 January 2023

The microtubule-associated conserved protein tau has attracted significant attention because of its essential role in the formation of pathological changes in the nervous system, which can reduce longevity. The study of the effects caused by tau dysf...

  • Article
  • Open Access
8 Citations
3,140 Views
14 Pages

1 February 2024

Betulinic acid (BetA), a triterpenoid derivative found abundantly in the plant kingdom, has emerged as a promising candidate for promoting longevity. Many research studies have shown its antioxidant, anti-inflammatory, antiviral, and anticancer activ...

  • Article
  • Open Access
17 Citations
5,046 Views
13 Pages

Research on Lifespan Prediction of Cross-Linked Polyethylene Material for XLPE Cables

  • Yi Zhang,
  • Zaijun Wu,
  • Cheng Qian,
  • Xiao Tan,
  • Jinggang Yang and
  • Linlin Zhong

4 August 2020

In this paper, cross-linked polyethylene (XLPE) cables of the same batch from Factory A, which ran from 1 to 8 years in Jiangsu Province, are sampled. Some widely accepted aging characterization methods of XLPE cables such as the gel content test, di...

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