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Keywords = intentional tooth replantation

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16 pages, 722 KB  
Review
Intentional Tooth Replantation: Current Evidence and Future Research Directions for Case Selection, Extraction Approaches, and Post-Operative Management
by Rahul Minesh Shah, Thomas Manders and Georgios Romanos
Dent. J. 2026, 14(1), 59; https://doi.org/10.3390/dj14010059 - 15 Jan 2026
Abstract
Background: Intentional tooth replantation (ITR) is a promising treatment option for preserving teeth in cases where conventional endodontic therapy is challenging, or when previous endodontic treatment and apicoectomy have been unsuccessful. The procedure involves extracting the compromised tooth, preserving the alveolar socket and [...] Read more.
Background: Intentional tooth replantation (ITR) is a promising treatment option for preserving teeth in cases where conventional endodontic therapy is challenging, or when previous endodontic treatment and apicoectomy have been unsuccessful. The procedure involves extracting the compromised tooth, preserving the alveolar socket and root surface, performing extraoral endodontic therapy, and replanting the tooth in the alveolar socket. Objective: An increase in evidence-based support for ITR has improved the viability of ITR as a treatment option for patients. This review aims to further establish and provide new areas of potential research for ITR with respect to root morphology, extraction, and surgical techniques, maintenance of the tooth socket, and methods for post-op stabilization. Materials and Methods: A literature review was performed across PubMed from 1 January 1980 to 1 July 2025, with a focus on oral surgery techniques, atraumatic extraction techniques, topographical discrepancies in root system anatomy, and ITR procedural outcomes. Conclusions: Although ITR is not a common procedure performed in contemporary clinical practice, gathering sufficient data on the variables influencing the procedure may help patient outcome and improve communication between the endodontist and oral surgeons. Full article
(This article belongs to the Section Dental Education)
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12 pages, 1899 KB  
Case Report
A Novel Surgical Treatment Approach for Vertical Root Fractures of Endodontically Treated Molars: A Report of 3 Cases
by Nuo Chen, Chang Lu, Xinling He, Yuexing Zheng, Ying Yang and Wei Fan
J. Clin. Med. 2025, 14(24), 8966; https://doi.org/10.3390/jcm14248966 - 18 Dec 2025
Viewed by 509
Abstract
Background: Vertical root fracture (VRF) is a severe complication of endodontically treated teeth with a poor prognosis. Despite many tentative tooth-preserving approaches, the current main treatment remains tooth extraction or root resection, which is largely due to the difficulty in balancing the mechanical [...] Read more.
Background: Vertical root fracture (VRF) is a severe complication of endodontically treated teeth with a poor prognosis. Despite many tentative tooth-preserving approaches, the current main treatment remains tooth extraction or root resection, which is largely due to the difficulty in balancing the mechanical strength for fracture fixation and biological properties for periodontal healing. Moreover, all documented reports regarding VRF repairing so far were limited to anterior teeth and premolars. Thus, the objective of this case report was to present a novel surgical treatment approach for repairing VRF of molars. Methods: Three patients (2 females, 1 male; aged 30–33 years) with endodontically treated molars (Tooth #46, #16, #37) diagnosed with VRF were treated with a dual-layered repair approach with modified fracture lines and retention forms through intentional replantation. Results: After 18, 21, and 36 months of follow-up, respectively, all three cases showed no clinical symptoms, normal tooth mobility and periodontal probing, as well as reduced periradicular radiolucency on radiographs. Root resorption or ankylosis was not observed. Conclusions: The novel surgical treatment approach demonstrates effectiveness in preserving endodontically treated molars with VRF, but its long-term treatment results for various VRF of molars need further randomized and controlled clinical investigations. Full article
(This article belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
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14 pages, 3540 KB  
Case Report
Digitally Guided Modified Intentional Replantation for a Tooth with Hopeless Periodontal Prognosis: A Case Report
by Raul Cuesta Román, Ángel Arturo López-González, Joan Obrador de Hevia, Sebastiana Arroyo Bote, Hernán Paublini Oliveira and Pere Riutord-Sbert
Diagnostics 2025, 15(23), 3080; https://doi.org/10.3390/diagnostics15233080 - 3 Dec 2025
Viewed by 610
Abstract
Background and Clinical Significance: Advanced periodontitis with severe vertical bone loss and grade III mobility is usually managed by extraction and implant placement. Digital workflows and modern regenerative techniques have opened the possibility of preserving teeth that would traditionally be considered for extraction. [...] Read more.
Background and Clinical Significance: Advanced periodontitis with severe vertical bone loss and grade III mobility is usually managed by extraction and implant placement. Digital workflows and modern regenerative techniques have opened the possibility of preserving teeth that would traditionally be considered for extraction. This report describes a digitally guided modified intentional replantation (MIR) protocol applied to a maxillary tooth with severe periodontal involvement and unfavourable prognosis. Case Presentation: A 68-year-old male, non-smoker, with a history of heart transplantation under stable medical control, presented with generalized Stage IV, Grade C periodontitis. Tooth 21 showed >75% vertical bone loss, probing depths ≥ 9 mm, bleeding on probing, and grade III mobility. After non-surgical therapy and periodontal stabilization, a CAD/CAM-assisted MIR procedure was planned. Cone-beam computed tomography (CBCT) and a 3D-printed tooth replica were used to design a surgical guide for a new recipient socket. The tooth was atraumatically extracted, stored in chilled sterile saline, and managed extraorally for approximately 10 min. Apicoectomy and retrograde sealing with Biodentine® were performed, followed by immediate replantation into the digitally prepared socket, semi-rigid splinting, and guided tissue regeneration using autologous bone chips, xenograft (Bio-Oss®), enamel matrix derivative (Emdogain®), and a collagen membrane (Bio-Gide®). A conventional orthograde root canal treatment was completed within the first month. At 12 months, tooth 21 exhibited grade 0 mobility, probing depths of 3–4 mm without bleeding on probing, and stable soft tissues. Standardized periapical radiographs and CBCT showed radiographic bone fill within the previous defect and a continuous periodontal ligament-like space, with no signs of ankylosis or root resorption. The tooth was fully functional and asymptomatic. Conclusions: In this medically complex patient, digitally guided MIR allowed preservation of a tooth with severe periodontal involvement and poor prognosis, achieving favourable short-term clinical and radiographic outcomes. While long-term data and larger series are needed, MIR may be considered a tooth-preserving option in carefully selected cases as an alternative to immediate extraction and implant placement. Full article
(This article belongs to the Section Clinical Diagnosis and Prognosis)
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12 pages, 1786 KB  
Article
Assessment of Bone Height Changes Based on the Cone–Beam Computed Tomography Following Intentional Replantation for Periodontally Compromised Teeth
by So-hyun Park, Seung-Heon Paek, Bongju Kim and Jung-Tae Lee
Medicina 2023, 59(1), 40; https://doi.org/10.3390/medicina59010040 - 25 Dec 2022
Cited by 3 | Viewed by 3098
Abstract
Background and Objectives; This study aimed to evaluate the clinical outcomes and bone changes before and after intentional replantation (IR) for periodontally compromised teeth by using cone–beam computed tomography (CBCT). Materials and Methods; Fourteen periodontally involved teeth were selected for IR. [...] Read more.
Background and Objectives; This study aimed to evaluate the clinical outcomes and bone changes before and after intentional replantation (IR) for periodontally compromised teeth by using cone–beam computed tomography (CBCT). Materials and Methods; Fourteen periodontally involved teeth were selected for IR. A preoperative orthodontic procedure was performed to apply luxation, and the tooth was then gently extracted. Retrograde filling of the root-end canal was performed. Once the tooth was repositioned in the socket, it was splinted with the adjacent tooth. After three months, prosthetic restoration was performed. Results; Clinical parameters and CBCT images were obtained before and after the IR procedure. The height of the alveolar bone was measured on the CBCT images by using software. Most preoperative symptoms, including pain, mobility, probing depth (PD) and bleeding on probing (BOP), significantly decreased after IR (pain: 4.71 to 1.00; mobility: 1.36 to 0.29; PD: 5.60 to 2.85; BOP: 3.50 to 0.79). CBCT analysis indicated an increase in bone height after IR (the amount of change: maxilla, 4.00; mandible, 1.95). Conclusions; A previous study reported that IR for periodontally involved teeth is quite limited. However, in this study, IR of periodontally compromised teeth showed favorable results in clinical and radiographic evaluations, suggesting that IR may be an alternative to extraction of teeth with periodontal disease. Full article
(This article belongs to the Special Issue Recent Advances in Periodontics and Dental Implantology)
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17 pages, 1270 KB  
Systematic Review
Intentional Replantation of Single-Rooted and Multi-Rooted Teeth: A Systematic Review
by Massimo Pisano, Federica Di Spirito, Stefano Martina, Giuseppe Sangiovanni, Francesco D’Ambrosio and Alfredo Iandolo
Healthcare 2023, 11(1), 11; https://doi.org/10.3390/healthcare11010011 - 21 Dec 2022
Cited by 23 | Viewed by 6229
Abstract
The technique of intentional replantation can provide a second chance to save teeth that would be destined for extraction. Therefore, the present systematic review aimed primarily to estimate tooth survival after intentional replantation and secondarily to compare treatment outcomes in single-rooted and multi-rooted [...] Read more.
The technique of intentional replantation can provide a second chance to save teeth that would be destined for extraction. Therefore, the present systematic review aimed primarily to estimate tooth survival after intentional replantation and secondarily to compare treatment outcomes in single-rooted and multi-rooted teeth. The study protocol was developed before the analysis according to the Preferred Reporting Items for Systematic Review and Meta-Analyses guidelines. Articles were electronically searched in PubMed/MEDLINE, the COCHRANE library and Google Scholar by two independent reviewers, and those that met the eligibility criteria were included. A statistical analysis using the chi-square test with a p-value of <0.05 was performed on the reported outcomes of intentional replantation. A total of 44 single-rooted replanted teeth with five failures (11.36%) and 42 multi-rooted replanted teeth with six failures (14.28%) were reported in the literature, corresponding to a survival rate of 88.64% and 85.57%, respectively. The overall survival rate for the replantation procedure was 86.7%, indicating that intentional replantation can be considered a safe therapeutic choice, with no statistically significant difference between the survival rates of single-rooted and multi-rooted replanted teeth. Full article
(This article belongs to the Special Issue Oral Healthcare: Diagnosis, Prevention and Treatment)
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10 pages, 2325 KB  
Case Report
Intentional Replantation as a Starting Approach for a Multidisciplinary Treatment of a Mandibular Second Molar: A Case Report
by João Miguel Santos, Joana A. Marques, Margarida Esteves, Vítor Sousa, Paulo J. Palma and Sérgio Matos
J. Clin. Med. 2022, 11(17), 5111; https://doi.org/10.3390/jcm11175111 - 30 Aug 2022
Cited by 9 | Viewed by 6035
Abstract
Intentional replantation (IR) may offer a solution for persistent periapical lesions associated with endodontically treated teeth. A 35-year-old male patient presented with pain associated with the left mandibular second molar and hypoesthesia. Upon clinical examination, increased probing pocket depth in the mid-buccal surface [...] Read more.
Intentional replantation (IR) may offer a solution for persistent periapical lesions associated with endodontically treated teeth. A 35-year-old male patient presented with pain associated with the left mandibular second molar and hypoesthesia. Upon clinical examination, increased probing pocket depth in the mid-buccal surface was detected. Cone beam computed tomography revealed a previous non-surgical root canal treatment, with root canal filling material extrusion adjacent to the inferior alveolar nerve, a fractured instrument in the mesial root, and a large periapical radiolucency involving both teeth 37 and 36. A diagnosis of symptomatic post-treatment apical periodontitis was established. After discussing treatment options with the patient, an IR of tooth 37 was performed. Extra-oral procedures were completed in 17 min. At 9 months, hypoesthesia resolution was reported, and apical healing was radiographically observed. After 2.5 years, the replanted tooth showed extensive root resorption. An extraction with alveolar ridge preservation, using leukocyte-platelet rich fibrin (L-PRF), was performed. Six months after tooth extraction and regeneration, implant placement surgery was carried out. IR presents a valid treatment modality for the management of post-treatment apical periodontitis. When orthograde retreatment or apical microsurgery prove to be unfeasible, IR is a unique procedure with the potential to promote tooth preservation in properly selected cases. Although unsuccessful after 2.5 years, the IR of tooth 37 allowed for bone regeneration, the maintenance of tooth 36 vitality, and hypoesthesia resolution. Full article
(This article belongs to the Special Issue New Frontiers in Endodontic Dentistry)
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