Search Results (37)

Recent advances in microbiome studies have deepened our understanding of endosymbionts and gut-associated microbiota in host biology. Of those, lepidopteran systems in particular harbor a complex and diverse microbiome with various microbial taxa that are stable and transmitted between larval and adult stages, and others that are transient and context-dependent. We highlight key microorganisms—including Bacillus, Lactobacillus, Escherichia coli, Pseudomonas, Rhizobium, Fusarium, Aspergillus, Saccharomyces, Bifidobacterium, and Wolbachia—that play critical roles in microbial ecology, biotechnology, and microbiome studies. The fitness implications of these microbial communities can be variable; some microbes improve host performance, while others neither positively nor negatively impact host fitness, or their impact is undetectable. This review examines the central position played by the gut microbiota in interactions of insects with plants, highlighting the functions of the microbiota in the manipulation of the behavior of herbivorous pests, modulating plant physiology, and regulating higher trophic levels in natural food webs. It also bridges microbiome ecology and applied pest management, emphasizing S. frugiperda as a model for symbiont-based intervention. As gut microbiota are central to the life history of herbivorous pests, we consider how these interactions can be exploited to drive the development of new, environmentally sound biocontrol strategies. Novel biotechnological strategies, including symbiont-based RNA interference (RNAi) and paratransgenesis, represent promising but still immature technologies with major obstacles to overcome in their practical application. However, microbiota-mediated pest control is an attractive strategy to move towards sustainable agriculture. Significantly, the gut microbiota of S. frugiperda is essential for S. frugiperda to adapt to a wide spectrum of host plants and different ecological niches. Studies have revealed that the microbiome of S. frugiperda has a close positive relationship with the fitness and susceptibility to entomopathogenic fungi; therefore, targeting the S. frugiperda microbiome may have good potential for innovative biocontrol strategies in the future. Full article

Antimicrobial resistance represents one of the most critical public health challenges of the 21st century. The emergence of multidrug resistance (MDR) in bacterial and fungal pathogens to diverse chemical agents severely impedes the effective treatment of diseases such as cancer and systemic infections. The rapid escalation of microbial resistance underscores the urgent need for the discovery of novel antimicrobial agents and innovative approaches to drug development. In both clinical and industrial contexts, the identification of new antibiotics and antifungals remains pivotal for pathogen control. Current research efforts focus on the development of alternative formulations that offer high efficacy, reduced resistance potential, minimal side effects, and synergistic interactions, particularly those derived from natural sources. Filamentous fungi originating from extreme environments have evolved to thrive under harsh conditions, making them promising reservoirs of bioactive metabolites with unique structural and functional properties. These fungi exhibit potent antimicrobial activity through diverse mechanisms that disrupt essential cellular processes in pathogens. Despite their remarkable potential, the bioprospecting of extremophilic filamentous fungi for drug development remains underexplored. This highlights the necessity for expanded research into the efficacy and safety of their derived compounds. This review aims to emphasize the capacity of extremophilic fungi to produce antimicrobial agents, elucidate resistance mechanisms, characterize fungal bioactive extracts, and analyze their molecular actions in the context of their extreme ecological niches. Full article

The study of bacteriocins has significantly enhanced our understanding of microbial interactions, notably within the genus Streptococcus. Among the most functionally diverse and clinically relevant bacteriocins are those belonging to the lantibiotic class, which exhibit potent antimicrobial properties and are central to the competitive dynamics of streptococcal species. This review focuses on the discovery and characterization of bacteriocins produced by Streptococcus pyogenes and Streptococcus salivarius, emphasizing their biological significance within their exclusive human host. A cornerstone of these studies has been the development and application of the pioneer agar culture-based bacteriocin detection methodology, known as streptococcal bacteriocin fingerprinting. This approach has proven invaluable for the initial detection and differentiation of a wide array of bacteriocin-like inhibitory substances (BLIS) in streptococcal populations. A central theme of this review is the diverse biological roles of lantibiotics in S. pyogenes and S. salivarius, particularly in relation to microbial competition, colonization dynamics, and host interactions. The expression of lantibiotic determinants provides distinct advantages to the producing strain, including enhanced niche establishment and the ability to suppress competing microbes. Furthermore, the presence of specific lantibiotic immunity mechanisms safeguards the producer from self-inhibition and potential antagonism from closely related competitors. In S. pyogenes, lantibiotic production has been implicated in virulence modulation, raising important questions about its role in pathogenicity and host immune evasion. Conversely, S. salivarius, a prominent commensal and probiotic candidate species, utilizes its lantibiotic arsenal to confer colonization benefits and mediate beneficial interactions, especially within the oral and upper respiratory tract microbiomes. The implications of in situ lantibiotic expression extend beyond microbial ecology, presenting opportunities for innovative probiotic and therapeutic applications. The potential for harnessing bacteriocin-producing streptococci in antimicrobial interventions, particularly in combating antibiotic-resistant pathogens, underscores the translational relevance of these findings. This review integrates historical and contemporary perspectives on streptococcal bacteriocin research, providing insights into future avenues for leveraging these bioactive peptides in clinical and biotechnological contexts. Full article

The study of the fungal communities of the skin constitutes a pivotal component of skin microbiome research. Within these communities, the genus Malassezia stands out as a major constituent, representing 50% to 80% of the total fungal colonization on the skin of healthy individuals. The excessive growth or metabolic irregularities of this genus are intimately connected with the onset of various skin disorders that are intrinsically linked to its lipid-dependent nature. Cutaneous lipid metabolism is indispensable for maintaining the skin barrier function and skin health. Malassezia possesses the ability to encode multiple lipase genes, and the secretion of these lipases plays a pivotal role in the survival strategies of the fungi. This review explores recent advances in the ecological niche of Malassezia in skin microecological homeostasis, its mechanism of disrupting skin lipids through catabolic metabolites, and the relationship between this disruption of the skin lipid barrier and skin diseases. This review offers a reference for future research on the mechanisms by which Malassezia affects lipid metabolism and provides a theoretical foundation for the development of innovative therapeutic approaches for dermatological conditions. Full article

Rural tourism, traditionally a niche sector, has gained significance due to changes in societal conditions, emerging as one of the most resilient forms of tourism. This article uses bibliometric analysis to explore the development and current trends in rural tourism research. Data were sourced from the Web of Science, yielding 1675 articles published between 1967 and 2023. Results reveal an average annual significant growth between 2008 and 2015, when 54.4% of all articles were published. Notable peaks include 142 publications in 2014 and a record 1230 citations in 2023, averaging 20.42 citations per article. Key contributions include identifying highly cited works, prolific authors, and leading institutions. Influential researchers such as Hall C. Michael, with 602 publications and an h-index of 67, and Carvalho Celia, a prominent European author, have shaped the field. The Universidad de Extremadura and the Chinese Academy of Sciences are among the top institutions, while journals like Sustainability and Tourism Management stand out for their influence. Six core research themes emerged: (a) the impact of rural tourism on agriculture and the environment, (b) the role of nature conservation and ecotourism in sustainable development, (c) ecological and sustainable approaches in biodiversity conservation, (d) biotechnological innovations in rural tourism, (e) demographic and social factors shaping outdoor recreation, and (f) the impact of rural tourism on sustainable development and community life. The study highlights the need for ongoing innovation to support sustainability goals and emphasizes the importance of understanding historical development and long-term trends in rural tourism research while offering insights into future research directions and practical applications. Full article

The adoption of innovations in rice cultivation is presumed to operate in a rational manner, wherein new technologies or practices that successfully increase productivity or resource efficiency are adopted by target farmers based on cost-benefit calculations. In contrast, this paper examines a case of a public initiative to promote the system of rice intensification (SRI), wherein farmers widely disadopted the technique despite reporting increasing yields and reduced water consumption. To explain this paradox, we use the concept of the socio-ecological niche to examine a range of social and institutional factors that shape farmers’ decision-making. These included (1) access to land and labour; (2) water management capacity; (3) the quality of networks for knowledge sharing. The research suggests that small variations in these categories among otherwise similar smallholder households can markedly shape farmers’ risk perceptions and tangible outcomes with SRI. The implication is that agricultural innovations should be judged within their wider social context rather than on narrow evaluations of agronomic efficiency. Importantly, this must involve greater feedback mechanisms from smallholders with a variety of socio-economic profiles to help shape the character of agricultural innovations and extension strategies. Full article

The deterioration of natural habitats for oak species has steadily occurred as a consequence of both climate change and human pressure. Therefore, detailed and reliable information about the geographic distribution of oak species under changing climate conditions is needed for diverse ecological and conservation practices. This study examined the habitat suitability of endemic Kasnak oak, Quercus vulcanica Boiss. & Heldr. ex Kotschy, an endemic that ranges across the Central Anatolia Region and surrounding mountains in Türkiye. The occurrence data were gathered through fieldwork, and new records were identified. Next, we applied ecological niche modeling to assess the past, present-day, and future potential geographic range of the species in Anatolia. Projections for the Last Glacial Maximum indicate that most of the suitable areas for Kasnak oak were in southern Anatolia. However, present-day estimates suggest projections estimate suitable habitats in northern Anatolia and around the Anatolian Diagonal. According to future projections, the distribution of the species seems to decrease by 2100, with habitat suitability reduction ranging from 3.27% to 7.88%. Projections suggest a decrease in habitat suitability for the species, particularly in the western and southern Türkiye in the future. Moreover, the projections indicated that suitable habitats for the northern range of the species would likely persist until 2100, although they would diminish towards the northeast. The results can be effectively applied to enhance biodiversity conservation planning and management, leading to the development of innovative strategies. Full article

The increasing volume of personal motorized vehicles (PMVs) in cities has become a serious issue leading to congestion, noise, air pollution and high land consumption. To ensure the sustainability of urban transportation, it is imperative to transition the current transportation paradigm toward a more sustainable state. Transitions within socio-technical systems often arise from niche innovation. Therefore, this paper pursues the technical optimization of such a niche innovation by applying a technical sustainability perspective on an innovative mobility and logistics concept within a case study. This case study is based on a centrally managed connected, automated, shared and electric (CASE) vehicle fleet which might replace PMV use in urban city centers of the future. The key technical system components of the envisioned mobility and logistics concept are analyzed and optimized with regard to economic, ecological and social sustainability dimensions to maximize the overall sustainability of the ecosystem. Specifically, this paper identifies key challenges and proposes possible solutions across the vehicle components as well as the orchestration of the vehicles’ operations within the envisioned mobility and logistics concept. Thereby, the case study gives an example of how different engineering disciplines can contribute to different sustainability dimensions, highlighting the interdependences. Finally, the discussion concludes that the early integration of sustainability considerations in the technical optimization efforts of innovative transportation systems can provide an important building block for the transition of the current transportation paradigm to a more sustainable state. Full article

Against the backdrop of an ongoing energy revolution, this study measured the regional green energy efficiency and ecological niche suitability of high-tech industry innovation ecosystems using the Super-SBM and entropy methods. We employed panel data from 30 mainland provinces (excluding Tibet) from 2009 to 2021 to conduct a quasi-natural experiment using spatial difference-in-differences models and double machine learning models. This was performed in order to investigate the impact mechanisms of the transformation of ecological niche suitability within the innovation ecosystems of high-tech industries driven by regional breakthrough innovation change strategies on green energy efficiency. The findings of this study revealed the following: (1) Driven by regional breakthrough innovation strategies, the transformation of the ecological niche suitability of high-tech industry innovation ecosystems has significant and positive local effects and spillover effects on green energy efficiency. (2) Regional breakthrough innovation strategies have a significant and positive mediating transmission effect on green energy efficiency through the development and optimization of internal factors within the ecological niche suitability of high-tech industry innovation ecosystems, including innovation entities, support, vitality, resources, and environment. (3) The transformation of the ecological niche suitability of high-tech industry innovation ecosystems driven by regional breakthrough innovation strategies promotes the advancement and rationalization of the industrial structure, thus indirectly enhancing regional green energy efficiency. These findings are of paramount importance for propelling the next wave of regional disruptive innovation reform strategies, ensuring that the outcomes of these reforms drive the ecological niche suitability of high-tech industry innovation ecosystems toward the advancement and realization of clean and efficient energy utilization. Full article

Based on niche theory, this paper constructs an evaluation index system for regional innovation ecosystem suitability from four aspects: innovation benefits, innovation technology, innovation culture, and innovation policy. The niche evaluation model is used to calculate and compare the suitability and evolutionary momentum of the innovation ecosystems in nine prefecture-level cities in Hubei Province from 2017 to 2022. Using the grey prediction model GM (1,1), the development of niche suitability for the nine prefecture-level cities in Hubei Province over the next five years is predicted. The results showed that, from the perspective of the niche, the overall suitability of the innovation niches in the nine prefecture-level cities of Hubei Province is relatively low, with higher evolutionary momentum, and the two exhibited a reverse development trend. The forecast results indicated that the suitability of the innovation niches in the nine prefecture-level cities of Hubei Province will follow different development trends in the next five years, with central cities showing higher development than non-central cities. Accordingly, this study provides a more scientific method for the evaluation, monitoring, forecasting, and improvement of regional innovation ecosystems at the city level. It supports policy formulation and strategic planning for the nine prefecture-level cities in Hubei Province and other regions from the aspects of innovation benefits, innovation technology, innovation culture, and innovation policy. At the same time, this study also provides new research pathways for the academic community, encouraging scholars to adopt multidisciplinary and multi-faceted approaches to explore the complexity and dynamics of regional innovation ecosystems in depth. It utilizes this information to optimize and adjust regional innovation policies to better adapt to the needs of global innovation competition. Full article

The northern region of Chile boasts unique geographical features that support the emergence of geothermal effluents, salt lagoons, and coastal creeks. These extreme climate conditions create polyextreme habitats for microorganisms, particularly adapted to survive these harsh environments. These extremophilic microorganisms hold immense potential as a source of hydrolytic enzymes, among other biotechnological applications. In this study, we isolated 15 strains of aerobic thermophilic bacteria (45–70 °C) from sediment samples collected at five different ecological sites, including hot springs, geothermal fields, and lagoons in the Atacama Desert and Andes high planes. Analyses of the 16S rRNA gene sequences of the isolates showed a close genetic similarity (98–100%) with microorganisms of the genera Parageobacillus, Geobacillus, Anoxybacillus, and Aeribacillus. Notably, these thermophiles exhibited significant hydrolytic enzyme activity, particularly amylases, lipases, and proteases. These findings underscore the potential of using these thermophilic bacterial strains as an invaluable source of thermozymes with wide-ranging applications in diverse industries, such as detergent formulations, pharmaceutical processing, and food technology. This research highlights the ecological significance of these extreme environments in the Atacama Desert and Andes high plains, which serve as vital ecological niches housing extremophilic bacteria as a genetic source of relevant thermozymes, promising great potential for innovation in the biotechnology industry. Full article

This study explores the dynamics of emerging technology innovation ecosystems, viewing them as complex systems comprising social actors and knowledge artifacts engaged in innovation interactions. Employing a multilayer network perspective, we present a Social-Knowledge-Science-Technology (A-K-S-T) framework, examining both homogeneous and heterogeneous interactions among innovators and knowledge elements. Within this framework, we map out the technological landscape, identify ecological niches for specific actors and knowledge elements, and gauge knowledge proximity among innovators, revealing opportunities for collaboration and knowledge innovation. Using 5G technology as an illustrative example, key findings include the potential for innovation development in 5G, the need for enhanced collaboration among organizations in related technological fields, and the complementary nature of scientific and technological knowledge. This research contributes to innovation ecosystem literature, offering insights for management, governance, efficiency, and shared prosperity; meanwhile, it is a valuable reference for decision-makers to shape effective strategies. Full article

In the Mediterranean basin, agriculture and other forms of human land use have shaped the environment since ancient times. Intensive and extensive agricultural systems managed with a few cultured plant populations of improved varieties are a widespread reality in many Mediterranean countries. Despite this, historical cultural landscapes still exist in interior and less intensively managed rural areas. There, ancient fruit tree varieties have survived modern cultivation systems, preserving a unique genetic heritage. In this study, we mapped and characterized 106 living fruit trees of ancient varieties in the Basilicata region of southern Italy. Tree ages were determined through tree ring measurements and radiocarbon analyses. We uncovered some of the oldest scientifically dated fruit trees in the world. The oldest fruit species were olive (max age 680 ± 57 years), mulberry (647 ± 66 years), chestnut (636 ± 66 years), and pear (467 ± 89 years). These patriarchs hold a unique genetic resource; their preservation and genetic maintenance through agamic propagation are now promoted by the Lucan Agency for the Development and Innovation in Agriculture (ALSIA). Each tree also represents a hub for biodiversity conservation in agrarian ecosystems: their large architecture and time persistence guarantee ecological niches and micro-habitats suitable for flora and fauna species of conservation significance. Full article

Antimicrobial resistance (AMR) is a major global public health concern mainly affecting low- and middle-income countries (LMICs) due to lack of awareness, inadequate healthcare and sanitation infrastructure, and other environmental factors. In this study, we aimed to link microbial assembly and covariates (body mass index, smoking, and use of antibiotics) to gut microbiome structure and correlate the predictive antimicrobial gene prevalence (piARG) using PICRUSt2. We examined the gastrointestinal and oral microbial profiles of healthy adults in Pakistan through 16S rRNA gene sequencing with a focus on different ethnicities, antibiotic usage, drinking water type, smoking, and other demographic measures. We then utilised a suite of innovative statistical tools, driven by numerical ecology and machine learning, to address the above aims. We observed that drinking tap water was the main contributor to increased potential AMR signatures in the Pakistani cohort compared to other factors considered. Microbial niche breadth analysis highlighted an aberrant gut microbial signature of smokers with increased age. Moreover, covariates such as smoking and age impact the human microbial community structure in this Pakistani cohort. Full article

The global carbon neutrality target and policy context of China’s high-quality development cause pressure to and are the driving forces of the transformation and development of resource-based cities. The current paper constructs an indicator system based on the ecological niche theory to measure and spatiotemporally analyze the ecological niche for the high-quality development in 115 resource-based cities in China. The results show that, firstly, the high-quality-development niches in resource-based cities are clustered on a medium level. Secondly, the differences in the sub-dimensional niche breadths are greater overall, with minor differences in the niche of resource and energy and considerable differences in the niche of innovation potential. Thirdly, we characterize the overall development imbalance following a more pronounced temporal evolution from the low to high niche over the decade. Based on the results, recommendations are made for resource-based cities to pinpoint and classify their strategies. The exploration of the comparative status, evolutionary dynamics and development paths for high-quality development in Chinese resource-based cities in this paper provides a systematic reference for building a new pattern of synergistic and sustainable development under the new normal of China’s economy. Full article