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23 pages, 2752 KB  
Article
AI-Driven Outage Management with Exploratory Data Analysis, Predictive Modeling, and LLM-Based Interface Integration
by Kian Ansarinejad, Ying Huang and Nita Yodo
Energies 2025, 18(19), 5244; https://doi.org/10.3390/en18195244 (registering DOI) - 2 Oct 2025
Abstract
Power outages pose considerable risks to the reliability of electric grids, affecting both consumers and utilities through service disruptions and potential economic losses. This study analyzes a historical outage dataset from a Regional Transmission Organization (RTO) to reveal key patterns and trends that [...] Read more.
Power outages pose considerable risks to the reliability of electric grids, affecting both consumers and utilities through service disruptions and potential economic losses. This study analyzes a historical outage dataset from a Regional Transmission Organization (RTO) to reveal key patterns and trends that suggest outage management strategies. By integrating exploratory data analysis, predictive modeling, and a Large Language Model (LLM)-based interface integration, as well as data visualization techniques, we identify and present critical drivers of outage duration and frequency. A random forest regressor trained on features including planned duration, facility name, outage owner, priority, season, and equipment type proved highly effective for predicting outage duration with high accuracy. This predictive framework underscores the practical value of incorporating planning information and seasonal context in anticipating outage timelines. The findings of this study not only deepen the understanding of temporal and spatial outage dynamics but also provide valuable insights for utility companies and researchers. Utility companies can use these results to better predict outage durations, allocate resources more effectively, and improve service restoration time. Researchers can leverage this analysis to enhance future models and methodologies for studying outage patterns, ensuring that artificial intelligence (AI)-driven methods can contribute to improving management strategies. The broader impact of this study is to ensure that the insights gained can be applied to strengthen the reliability and resilience of power grids or energy systems in general. Full article
(This article belongs to the Special Issue Artificial Intelligence in Energy Sector)
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18 pages, 4415 KB  
Article
AI-Aided GPR Data Multipath Summation Using x-t Stacking Weights
by Nikos Economou, Sobhi Nasir, Said Al-Abri, Bader Al-Shaqsi and Hamdan Hamdan
NDT 2025, 3(4), 24; https://doi.org/10.3390/ndt3040024 (registering DOI) - 2 Oct 2025
Abstract
The Ground Penetrating Radar (GPR) method can image dielectric discontinuities in subsurface structures, which cause the reflection of electromagnetic (EM) waves. These discontinuities are imaged as reflectors in GPR sections, often distorted by diffracted energy. To focus the diffracted energy within the GPR [...] Read more.
The Ground Penetrating Radar (GPR) method can image dielectric discontinuities in subsurface structures, which cause the reflection of electromagnetic (EM) waves. These discontinuities are imaged as reflectors in GPR sections, often distorted by diffracted energy. To focus the diffracted energy within the GPR sections, migration is commonly used. The migration velocity of GPR data is a low-wavenumber attribute crucial for effective migration. Obtaining a migration velocity model, typically close to a Root Mean Square (RMS) model, from zero-offset (ZO) data requires analysis of the available diffractions, whose density and (x, t) coverage are random. Thus, the accuracy and efficiency of such a velocity model, whether for migration or interval velocity model estimation, are not guaranteed. An alternative is the multipath summation method, which involves the weighted stacking of constant velocity migrated sections. Each stacked section contributes to the final stack, weighted by a scalar value dependent on the constant velocity value used and its relation to its estimated mean velocity of the section. This method effectively focuses the GPR diffractions in the presence of low heterogeneity. However, when the EM velocity varies dramatically, 2D weights are needed. In this study, with the aid of an Artificial Intelligence (AI) algorithm that detects diffractions and uses their kinematic information, we generate a diffraction velocity model. This model is then used to assign 2D weights for the weighted multipath summation, aiming to focus the scattered energy within the GPR section. We describe this methodology and demonstrate its application in enhancing the lateral continuity of reflections. We compare it with the 1D multipath summation using simulated data and present its application on marble assessment GPR data for imaging cracks and discontinuities in the subsurface structure. Full article
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19 pages, 1517 KB  
Article
Decoding Anticancer Drug Response: Comparison of Data-Driven and Pathway-Guided Prediction Models
by Efstathios Pateras, Ioannis S. Vizirianakis, Mingrui Zhang, Georgios Aivaliotis, Georgios Tzimagiorgis and Andigoni Malousi
Future Pharmacol. 2025, 5(4), 58; https://doi.org/10.3390/futurepharmacol5040058 (registering DOI) - 2 Oct 2025
Abstract
Background/Objective: Predicting pharmacological response in cancer remains a key challenge in precision oncology due to intertumoral heterogeneity and the complexity of drug–gene interactions. While machine learning models using multi-omics data have shown promise in predicting pharmacological response, selecting the features with the highest [...] Read more.
Background/Objective: Predicting pharmacological response in cancer remains a key challenge in precision oncology due to intertumoral heterogeneity and the complexity of drug–gene interactions. While machine learning models using multi-omics data have shown promise in predicting pharmacological response, selecting the features with the highest predictive power critically affects model performance and biological interpretability. This study aims to compare computational and biologically informed gene selection strategies for predicting drug response in cancer cell lines and to propose a feature selection strategy that optimizes performance. Methods: Using gene expression and drug response data, we trained models on both data-driven and biologically informed gene sets based on the drug target pathways to predict IC50 values for seven anticancer drugs. Several feature selection methods were tested on gene expression profiles of cancer cell lines, including Recursive Feature Elimination (RFE) with Support Vector Regression (SVR) against gene sets derived from drug-specific pathways in KEGG and CTD databases. The predictability was comparatively analyzed using both AUC and IC50 values and further assessed on proteomics data. Results: RFE with SVR outperformed other computational methods, while pathway-based gene sets showed lower performance compared to data-driven methods. The integration of computational and biologically informed gene sets consistently improved prediction accuracy across several anticancer drugs, while the predictive value of the corresponding proteomic features was significantly lower compared with the mRNA profiles. Conclusions: Integrating biological knowledge into feature selection enhances both the accuracy and interpretability of drug response prediction models. Integrative approaches offer a more robust and generalizable framework with potential applications in biomarker discovery, drug repurposing, and personalized treatment strategies. Full article
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22 pages, 782 KB  
Article
Hybrid CNN-Swin Transformer Model to Advance the Diagnosis of Maxillary Sinus Abnormalities on CT Images Using Explainable AI
by Mohammad Alhumaid and Ayman G. Fayoumi
Computers 2025, 14(10), 419; https://doi.org/10.3390/computers14100419 - 2 Oct 2025
Abstract
Accurate diagnosis of sinusitis is essential due to its widespread prevalence and its considerable impact on patient quality of life. While multiple imaging techniques are available for detecting maxillary sinus, computed tomography (CT) remains the preferred modality because of its high sensitivity and [...] Read more.
Accurate diagnosis of sinusitis is essential due to its widespread prevalence and its considerable impact on patient quality of life. While multiple imaging techniques are available for detecting maxillary sinus, computed tomography (CT) remains the preferred modality because of its high sensitivity and spatial resolution. Although recent advances in deep learning have led to the development of automated methods for sinusitis classification, many existing models perform poorly in the presence of complex pathological features and offer limited interpretability, which hinders their integration into clinical workflows. In this study, we propose a hybrid deep learning framework that combines EfficientNetB0, a convolutional neural network, with the Swin Transformer, a vision transformer, to improve feature representation. An attention-based fusion module is used to integrate both local and global information, thereby enhancing diagnostic accuracy. To improve transparency and support clinical adoption, the model incorporates explainable artificial intelligence (XAI) techniques using Gradient-weighted Class Activation Mapping (Grad-CAM). This allows for visualization of the regions influencing the model’s predictions, helping radiologists assess the clinical relevance of the results. We evaluate the proposed method on a curated maxillary sinus CT dataset covering four diagnostic categories: Normal, Opacified, Polyposis, and Retention Cysts. The model achieves a classification accuracy of 95.83%, with precision, recall, and F1 score all at 95%. Grad-CAM visualizations indicate that the model consistently focuses on clinically significant regions of the sinus anatomy, supporting its potential utility as a reliable diagnostic aid in medical practice. Full article
23 pages, 3987 KB  
Article
From Symmetry to Semantics: Improving Heritage Point Cloud Classification with a Geometry-Aware, Uniclass-Informed Taxonomy for Random Forest Implementation in Automated HBIM Modelling
by Aleksander Gil and Yusuf Arayici
Symmetry 2025, 17(10), 1635; https://doi.org/10.3390/sym17101635 - 2 Oct 2025
Abstract
Heritage Building Information Modelling (HBIM) requires the accurate classification of diverse building elements from 3D point clouds. This study presents a novel classification approach integrating a bespoke Uniclass-derived taxonomy with a hierarchical Random Forest model. It was applied to the 17th-century Queen’s House [...] Read more.
Heritage Building Information Modelling (HBIM) requires the accurate classification of diverse building elements from 3D point clouds. This study presents a novel classification approach integrating a bespoke Uniclass-derived taxonomy with a hierarchical Random Forest model. It was applied to the 17th-century Queen’s House in Greenwich, a building rich in classical architectural elements whose geometric properties are often defined by principles of symmetry. The bespoke classification was implemented across three levels (50 mm, 20 mm, 5 mm point cloud resolutions) and evaluated against the prior experiment that used Uniclass classification. Results showed a substantial improvement in classification precision and overall accuracy at all levels. The Level 1 classifier’s accuracy increased by 15% of points (relative ~50% improvement) with the bespoke classification taxonomy, reducing the misclassifications and error propagation in subsequent levels. This research demonstrates that tailoring the Uniclass building classification for heritage-specific geometry significantly enhances machine learning performance, which, to date, has not been published in the academic domain. The findings underscore the importance of adaptive taxonomies and suggest pathways for integrating multi-scale features and advanced learning methods to support automated HBIM workflows. Full article
(This article belongs to the Section Computer)
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38 pages, 6435 KB  
Article
FedResilience: A Federated Classification System to Ensure Critical LTE Communications During Natural Disasters
by Alvaro Acuña-Avila, Christian Fernández-Campusano, Héctor Kaschel and Raúl Carrasco
Systems 2025, 13(10), 866; https://doi.org/10.3390/systems13100866 - 2 Oct 2025
Abstract
Natural disasters can disrupt communication services, leading to severe consequences in emergencies. Maintaining connectivity and communication quality during crises is crucial for coordinating rescues, providing critical information, and ensuring reliable and secure service. This study proposes FedResilience, a Federated Learning (FL) system for [...] Read more.
Natural disasters can disrupt communication services, leading to severe consequences in emergencies. Maintaining connectivity and communication quality during crises is crucial for coordinating rescues, providing critical information, and ensuring reliable and secure service. This study proposes FedResilience, a Federated Learning (FL) system for classifying Long-Term Evolution (LTE) network coverage in both normal operation and natural disaster scenarios. A three-tier architecture is implemented: (i) edge nodes, (ii) a central aggregation server, and (iii) a batch processing interface. Five FL aggregation methods (FedAvg, FedProx, FedAdam, FedYogi, and FedAdagrad) were evaluated under normal conditions and disaster simulations. The results show that FedAdam outperforms the other methods under normal conditions, achieving an F1 score of 0.7271 and a Global System Adherence (SAglobal) of 91.51%. In disaster scenarios, FedProx was superior, with an F1 score of 0.7946 and SAglobal of 61.73%. The innovation in this study is the introduction of the System Adherence (SA) metric to evaluate the predictive fidelity of the model. The system demonstrated robustness against Non-Independent and Identically Distributed (non-IID) data distributions and the ability to handle significant class imbalances. FedResilience serves as a tool for companies to implement automated corrective actions, contributing to the predictive maintenance of LTE networks through FL while preserving data privacy. Full article
(This article belongs to the Special Issue Data-Driven Decision Making for Complex Systems)
29 pages, 2319 KB  
Article
Research on the Development of a Building Model Management System Integrating MQTT Sensing
by Ziang Wang, Han Xiao, Changsheng Guan, Liming Zhou and Daiguang Fu
Sensors 2025, 25(19), 6069; https://doi.org/10.3390/s25196069 - 2 Oct 2025
Abstract
Existing building management systems face critical limitations in real-time data integration, primarily relying on static models that lack dynamic updates from IoT sensors. To address this gap, this study proposes a novel system integrating MQTT over WebSocket with Three.js visualization, enabling real-time sensor-data [...] Read more.
Existing building management systems face critical limitations in real-time data integration, primarily relying on static models that lack dynamic updates from IoT sensors. To address this gap, this study proposes a novel system integrating MQTT over WebSocket with Three.js visualization, enabling real-time sensor-data binding to Building Information Models (BIM). The architecture leverages MQTT’s lightweight publish-subscribe protocol for efficient communication and employs a TCP-based retransmission mechanism to ensure 99.5% data reliability in unstable networks. A dynamic topic-matching algorithm is introduced to automate sensor-BIM associations, reducing manual configuration time by 60%. The system’s frontend, powered by Three.js, achieves browser-based 3D visualization with sub-second updates (280–550 ms latency), while the backend utilizes SpringBoot for scalable service orchestration. Experimental evaluations across diverse environments—including high-rise offices, industrial plants, and residential complexes—demonstrate the system’s robustness: Real-time monitoring: Fire alarms triggered within 2.1 s (22% faster than legacy systems). Network resilience: 98.2% availability under 30% packet loss. User efficiency: 4.6/5 satisfaction score from facility managers. This work advances intelligent building management by bridging IoT data with interactive 3D models, offering a scalable solution for emergency response, energy optimization, and predictive maintenance in smart cities. Full article
(This article belongs to the Section Intelligent Sensors)
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45 pages, 2430 KB  
Article
Adolescent Smartphone Overdependence in South Korea: A Place-Stratified Evaluation of Conceptually Informed AI/ML Modeling
by Andrew H. Kim, Uibin Lee, Yohan Cho, Sangmi Kim and Vatsal Shah
Int. J. Environ. Res. Public Health 2025, 22(10), 1515; https://doi.org/10.3390/ijerph22101515 - 2 Oct 2025
Abstract
Smartphone overdependence among South Korean adolescents, affecting nearly 40%, poses a growing public health concern, with usage patterns varying by regional context. Leveraging conceptually informed AI/ML models, this study (1) develops a high-performing low-risk screening tool to monitor disease burden, (2) leverages AI/ML [...] Read more.
Smartphone overdependence among South Korean adolescents, affecting nearly 40%, poses a growing public health concern, with usage patterns varying by regional context. Leveraging conceptually informed AI/ML models, this study (1) develops a high-performing low-risk screening tool to monitor disease burden, (2) leverages AI/ML to explore psychologically meaningful constructs, and (3) provides place-based policy implication profiles to inform public health policy. This study uses data from 1873 adolescents in the 2023 Smartphone Overdependence Survey by the National Information Society Agency (NISA) in South Korea. Across the sample, the adolescents were about 14 years old (SD = 2.4) and equally distributed by sex (48.1% male). We then conceptually selected 131 features across two domains and 10 identified constructs. A nested modeling approach identified a low-risk screening tool using 59 features that achieved strong predictive accuracy (AUC = 81.5%), with Smartphone Use Case features contributing approximately 20% to performance. Construct-specific models confirmed the importance of Smartphone Use Cases, Perceived Digital Competence and Risk, and Consequences and Dependence (AUC range: 80.6–89.1%) and uncovered cognitive patterns warranting further study. Place-stratified analysis revealed substantial regional variation in model performance (AUC range: 71.4–91.1%) and distinct local feature importance. Overall, this study demonstrated the value of integrating conceptual frameworks with AI/ML to detect adolescent smartphone overdependence, offering novel approaches to monitoring disease burden, advancing construct-level insights, and providing targeted place-based public health policy recommendations within the South Korean context. Full article
(This article belongs to the Special Issue Problematic Internet and Smartphone Use as a Public Health Concern)
15 pages, 2373 KB  
Article
LLM-Empowered Kolmogorov-Arnold Frequency Learning for Time Series Forecasting in Power Systems
by Zheng Yang, Yang Yu, Shanshan Lin and Yue Zhang
Mathematics 2025, 13(19), 3149; https://doi.org/10.3390/math13193149 - 2 Oct 2025
Abstract
With the rapid evolution of artificial intelligence technologies in power systems, data-driven time-series forecasting has become instrumental in enhancing the stability and reliability of power systems, allowing operators to anticipate demand fluctuations and optimize energy distribution. Despite the notable progress made by current [...] Read more.
With the rapid evolution of artificial intelligence technologies in power systems, data-driven time-series forecasting has become instrumental in enhancing the stability and reliability of power systems, allowing operators to anticipate demand fluctuations and optimize energy distribution. Despite the notable progress made by current methods, they are still hindered by two major limitations: most existing models are relatively small in architecture, failing to fully leverage the potential of large-scale models, and they are based on fixed nonlinear mapping functions that cannot adequately capture complex patterns, leading to information loss. To this end, an LLM-Empowered Kolmogorov–Arnold frequency learning (LKFL) is proposed for time series forecasting in power systems, which consists of LLM-based prompt representation learning, KAN-based frequency representation learning, and entropy-oriented cross-modal fusion. Specifically, LKFL first transforms multivariable time-series data into text prompts and leverages a pre-trained LLM to extract semantic-rich prompt representations. It then applies Fast Fourier Transform to convert the time-series data into the frequency domain and employs Kolmogorov–Arnold networks (KAN) to capture multi-scale periodic structures and complex frequency characteristics. Finally, LKFL integrates the prompt and frequency representations through an entropy-oriented cross-modal fusion strategy, which minimizes the semantic gap between different modalities and ensures full integration of complementary information. This comprehensive approach enables LKFL to achieve superior forecasting performance in power systems. Extensive evaluations on five benchmarks verify that LKFL sets a new standard for time-series forecasting in power systems compared with baseline methods. Full article
(This article belongs to the Special Issue Artificial Intelligence and Data Science, 2nd Edition)
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13 pages, 1111 KB  
Article
Enhancing Pediatric Asthma Homecare Management: The Potential of Deep Learning Associated with Spirometry-Labelled Data
by Heidi Cleverley-Leblanc, Johan N. Siebert, Jonathan Doenz, Mary-Anne Hartley, Alain Gervaix, Constance Barazzone-Argiroffo, Laurence Lacroix and Isabelle Ruchonnet-Metrailler
Appl. Sci. 2025, 15(19), 10662; https://doi.org/10.3390/app151910662 - 2 Oct 2025
Abstract
A critical factor contributing to the burden of childhood asthma is the lack of effective self-management in homecare settings. Artificial intelligence (AI) and lung sound monitoring could help address this gap. Yet, existing AI-driven auscultation tools focus on wheeze detection and often rely [...] Read more.
A critical factor contributing to the burden of childhood asthma is the lack of effective self-management in homecare settings. Artificial intelligence (AI) and lung sound monitoring could help address this gap. Yet, existing AI-driven auscultation tools focus on wheeze detection and often rely on subjective human labels. To improve the early detection of asthma worsening in children in homecare setting, we trained and evaluated a Deep Learning model based on spirometry-labelled lung sounds recordings to detect asthma exacerbation. A single-center prospective observational study was conducted between November 2020 and September 2022 at a tertiary pediatric pulmonology department. Electronic stethoscopes were used to record lung sounds before and after bronchodilator administration in outpatients. In the same session, children also underwent spirometry, which served as the reference standard for labelling the lung sound data. Model performance was assessed on an internal validation set using receiver operating characteristic (ROC) curves. A total of 16.8 h of lung sound recordings from 151 asthmatic pediatric outpatients were collected. The model showed promising discrimination performance, achieving an AUROC of 0.763 in the training set, but performance in the validation set was limited (AUROC = 0.398). This negative result demonstrates that acoustic features alone may not provide sufficient diagnostic information for the early detection of asthma attacks, especially in mostly asymptomatic outpatients typical of homecare settings. It also underlines the challenges introduced by differences in how digital stethoscopes process sounds and highlights the need to define the severity threshold at which acoustic monitoring becomes informative, and clinically relevant for home management. Full article
(This article belongs to the Special Issue Deep Learning and Data Mining: Latest Advances and Applications)
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16 pages, 237 KB  
Review
Norms of Masculinities and Gender Socialization Among Young Boys in South Africa: Implications for Gender-Based Violence, Policies, and Interventions
by Judith I. Ani and Lucky Norah Katende-Kyenda
Sexes 2025, 6(4), 54; https://doi.org/10.3390/sexes6040054 - 2 Oct 2025
Abstract
Masculinity norms and gender socialization play a critical role in shaping boys’ attitudes, behaviours, and interactions within society. In South Africa, historical legacies of colonialism and apartheid, coupled with deeply ingrained cultural and societal expectations, have contributed to rigid masculinity norms that emphasize [...] Read more.
Masculinity norms and gender socialization play a critical role in shaping boys’ attitudes, behaviours, and interactions within society. In South Africa, historical legacies of colonialism and apartheid, coupled with deeply ingrained cultural and societal expectations, have contributed to rigid masculinity norms that emphasize dominance, emotional restraint, and aggression. These constructs not only influence boys’ development but also have significant implications for gender-based violence (GBV). This paper explores how norms of masculinity and processes of gender socialization among boys in South Africa shape attitudes and behaviours that contribute to gender-based violence (GBV). The central aim is to offer a critical theoretical synthesis and contextual analysis that informs the development of gender-equitable policies and interventions. Drawing on theoretical frameworks such as hegemonic masculinities, intersectionality, and social learning theory, this study examines how historical, cultural, and socio-economic factors shape gender socialization and influence boys’ developmental trajectories. Through an intersectional lens, this paper underscores the urgent need to challenge harmful masculinity norms and promote alternative models that encourage emotional expression, empathy, and equitable gender relations. Finally, it provides recommendations on how these harmful norms can be disrupted through educational, community, media, and policy-level reforms to foster healthier masculinity norms and reduce GBV in South Africa. Full article
27 pages, 8112 KB  
Article
Detection of Abiotic Stress in Potato and Sweet Potato Plants Using Hyperspectral Imaging and Machine Learning
by Min-Seok Park, Mohammad Akbar Faqeerzada, Sung Hyuk Jang, Hangi Kim, Hoonsoo Lee, Geonwoo Kim, Young-Son Cho, Woon-Ha Hwang, Moon S. Kim, Insuck Baek and Byoung-Kwan Cho
Plants 2025, 14(19), 3049; https://doi.org/10.3390/plants14193049 - 2 Oct 2025
Abstract
As climate extremes increasingly threaten global food security, precision tools for early detection of crop stress have become vital, particularly for root crops such as potato (Solanum tuberosum L.) and sweet potato (Ipomoea batatas L. Lam.), which are especially susceptible to [...] Read more.
As climate extremes increasingly threaten global food security, precision tools for early detection of crop stress have become vital, particularly for root crops such as potato (Solanum tuberosum L.) and sweet potato (Ipomoea batatas L. Lam.), which are especially susceptible to environmental stressors throughout their life cycles. In this study, plants were monitored from the initial onset of seasonal stressors, including spring drought, heat, and episodes of excessive rainfall, through to harvest, capturing the full range of physiological and biochemical responses under seasonal, simulated conditions in greenhouses. The spectral data were obtained from regions of interest (ROIs) of each cultivar’s leaves, with over 3000 data points extracted per cultivar; these data were subsequently used for model development. A comprehensive classification framework was established by employing machine learning models, Support Vector Machine (SVM), Linear Discriminant Analysis (LDA), and Partial Least Squares-Discriminant Analysis (PLS-DA), to detect stress across various growth stages. Furthermore, severity levels were objectively defined using photoreflectance indices and principal component analysis (PCA) data visualizations, which enabled consistent and reliable classification of stress responses in both individual cultivars and combined datasets. All models achieved high classification accuracy (90–98%) on independent test sets. The application of the Successive Projections Algorithm (SPA) for variable selection significantly reduced the number of wavelengths required for robust stress classification, with SPA-PLS-DA models maintaining high accuracy (90–96%) using only a subset of informative bands. Furthermore, SPA-PLS-DA-based chemical imaging enabled spatial mapping of stress severity within plant tissues, providing early, non-invasive insights into physiological and biochemical status. These findings highlight the potential of integrating hyperspectral imaging and machine learning for precise, real-time crop monitoring, thereby contributing to sustainable agricultural management and reduced yield losses. Full article
(This article belongs to the Section Plant Modeling)
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25 pages, 3499 KB  
Article
Dual Machine Learning Framework for Predicting Long-Term Glycemic Change and Prediabetes Risk in Young Taiwanese Men
by Chung-Chi Yang, Sheng-Tang Wu, Ta-Wei Chu, Chi-Hao Liu and Yung-Jen Chuang
Diagnostics 2025, 15(19), 2507; https://doi.org/10.3390/diagnostics15192507 - 2 Oct 2025
Abstract
Background: Early detection of dysglycemia in young adults is important but underexplored. This study aimed to (1) predict long-term changes in fasting plasma glucose (δ-FPG) and (2) classify future prediabetes using complementary machine learning (ML) approaches. Methods: We analyzed 6247 Taiwanese men aged [...] Read more.
Background: Early detection of dysglycemia in young adults is important but underexplored. This study aimed to (1) predict long-term changes in fasting plasma glucose (δ-FPG) and (2) classify future prediabetes using complementary machine learning (ML) approaches. Methods: We analyzed 6247 Taiwanese men aged 18–35 years (mean follow-up 5.9 years). For δ-FPG (continuous outcome), random forest, stochastic gradient boosting (SGB), eXtreme gradient boosting (XGBoost), and elastic net were compared with multiple linear regression using Symmetric mean absolute percentage error (SMAPE), Root mean squared error (RMSE), Relative absolute error(RAE), and Root relative squared error (RRSE) Sensitivity analyses excluded baseline FPG (FPGbase). Shapley additive explanations(SHAP) values provided interpretability, and stability was assessed across 10 repeated train–test cycles with confidence intervals. For prediabetes (binary outcome), an XGBoost classifier was trained on top predictors, with class imbalance corrected by SMOTE-Tomek. Calibration and decision-curve analysis (DCA) were also performed. Results: ML models consistently outperformed regression on all error metrics. FPGbase was the dominant predictor in full models (100% importance). Without FPGbase, key predictors included body fat, white blood cell count, age, thyroid-stimulating hormone, triglycerides, and low-density lipoprotein cholesterol. The prediabetes classifier achieved accuracy 0.788, precision 0.791, sensitivity 0.995, ROC-AUC 0.667, and PR-AUC 0.873. At a high-sensitivity threshold (0.2892), sensitivity reached 99.53% (specificity 47.46%); at a balanced threshold (0.5683), sensitivity was 88.69% and specificity was 90.61%. Calibration was acceptable (Brier 0.1754), and DCA indicated clinical utility. Conclusions: FPGbase is the strongest predictor of glycemic change, but adiposity, inflammation, thyroid status, and lipids remain informative. A dual interpretable ML framework offers clinically actionable tools for screening and risk stratification in young men. Full article
(This article belongs to the Special Issue Metabolic Diseases: Diagnosis, Management, and Pathogenesis)
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18 pages, 1257 KB  
Article
Forecasting the Housing Market Sales in Italy: An MLP Neural Network Model
by Paolo Rosato and Matteo Galante
Real Estate 2025, 2(4), 16; https://doi.org/10.3390/realestate2040016 - 2 Oct 2025
Abstract
Using panel data on 99 Italian provinces in the period between 2005 and 2020, the research investigates the effects of fundamental economic factors on the home sales at the provincial level, in order to build a forecasting model using a non-linear artificial intelligence [...] Read more.
Using panel data on 99 Italian provinces in the period between 2005 and 2020, the research investigates the effects of fundamental economic factors on the home sales at the provincial level, in order to build a forecasting model using a non-linear artificial intelligence approach (MLP-Multiple Linear Perceptron neural network). There are multiple objectives to this: (a) to test the hypothesis that national, regional and local fundamentals such as interest rates, income, inflation rate, unemployment and demography affect the activity’s degree of the housing market; (b) to verify the effectiveness of a neural network in describing the dynamics of the real estate market; (c) to build a simulation model capable of predicting the effect of changes in fundamentals, also due to economic policy measures, on the market. Empirical results show that neural networks offer better capabilities than linear models in representing the complex relationships between the economic situation and the real estate market. The study provides useful information for regulators to improve the effectiveness of monetary policy to stabilize real estate markets as well as for stakeholders to draw up scenarios of market development. Full article
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24 pages, 9336 KB  
Article
Temporal-Aware and Intent Contrastive Learning for Sequential Recommendation
by Yuan Zhang, Yaqin Fan, Tiantian Sheng and Aoshuang Wang
Symmetry 2025, 17(10), 1634; https://doi.org/10.3390/sym17101634 - 2 Oct 2025
Abstract
In recent years, research in sequential recommendation has primarily refined user intent by constructing sequence-level contrastive learning tasks through data augmentation or by extracting preference information from the latent space of user behavior sequences. However, existing methods suffer from two critical limitations. Firstly, [...] Read more.
In recent years, research in sequential recommendation has primarily refined user intent by constructing sequence-level contrastive learning tasks through data augmentation or by extracting preference information from the latent space of user behavior sequences. However, existing methods suffer from two critical limitations. Firstly, they fail to account for how random data augmentation may introduce unreasonable item associations in contrastive learning samples, thereby perturbing sequential semantic relationships. Secondly, the neglect of temporal dependencies may prevent models from effectively distinguishing between incidental behaviors and stable intentions, ultimately impairing the learning of user intent representations. To address these limitations, we propose TCLRec, a novel temporal-aware and intent contrastive learning framework for sequential recommendation, incorporating symmetry into its architecture. During the data augmentation phase, the model employs a symmetrical contrastive learning architecture and incorporates semantic enhancement operators to integrate user preferences. By introducing user rating information into both branches of the contrastive learning framework, this approach effectively enhances the semantic relevance between positive sample pairs. Furthermore, in the intent contrastive learning phase, TCLRec adaptively attenuates noise information in the frequency domain through learnable filters, while in the pre-training phase of sequence-level contrastive learning, it introduces a temporal-aware network that utilizes additional self-supervised signals to assist the model in capturing both long-term dependencies and short-term interests from user behavior sequences. The model employs a multi-task training strategy that alternately performs intent contrastive learning and sequential recommendation tasks to jointly optimize user intent representations. Comprehensive experiments conducted on the Beauty, Sports, and LastFM datasets demonstrate the soundness and effectiveness of TCLRec, where the incorporation of symmetry enhances the model’s capability to represent user intentions. Full article
(This article belongs to the Section Computer)
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