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Keywords = image reconstruction analysis

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26 pages, 12108 KiB  
Article
Image Encryption Algorithm Based on an Improved Tent Map and Dynamic DNA Coding
by Wei Zhou, Xianwei Li and Zhenghua Xin
Entropy 2025, 27(8), 796; https://doi.org/10.3390/e27080796 - 26 Jul 2025
Viewed by 51
Abstract
As multimedia technologies evolve, digital images have become increasingly prevalent across various fields, highlighting an urgent demand for robust image privacy and security mechanisms. However, existing image encryption algorithms (IEAs) still face limitations in balancing strong security, real-time performance, and computational efficiency. Therefore, [...] Read more.
As multimedia technologies evolve, digital images have become increasingly prevalent across various fields, highlighting an urgent demand for robust image privacy and security mechanisms. However, existing image encryption algorithms (IEAs) still face limitations in balancing strong security, real-time performance, and computational efficiency. Therefore, we proposes a new IEA that integrates an improved chaotic map (Tent map), an improved Zigzag transform, and dynamic DNA coding. Firstly, a pseudo-wavelet transform (PWT) is applied to plain images to produce four sub-images I1, I2, I3, and I4. Secondly, the improved Zigzag transform and its three variants are used to rearrange the sub-image I1, and then the scrambled sub-image is diffused using XOR operation. Thirdly, an inverse pseudo-wavelet transform (IPWT) is employed on the four sub-images to reconstruct the image, and then the reconstructed image is encoded into a DNA sequence utilizing dynamic DNA encoding. Finally, the DNA sequence is scrambled and diffused employing DNA-level index scrambling and dynamic DNA operations. The experimental results and performance evaluations, including chaotic performance evaluation and comprehensive security analysis, demonstrate that our IEA achieves high key sensitivity, low correlation, excellent entropy, and strong resistance to common attacks. This highlights its potential for deployment in real-time, high-security image cryptosystems, especially in fields such as medical image security and social media privacy. Full article
(This article belongs to the Section Multidisciplinary Applications)
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24 pages, 10103 KiB  
Article
Design Technique and Efficient Polyphase Implementation for 2D Elliptically Shaped FIR Filters
by Doru Florin Chiper and Radu Matei
Sensors 2025, 25(15), 4644; https://doi.org/10.3390/s25154644 - 26 Jul 2025
Viewed by 54
Abstract
This paper presents a novel analytical approach for the efficient design of a particular class of 2D FIR filters, having a frequency response with an elliptically shaped support in the frequency plane. The filter design is based on a Gaussian shaped prototype filter, [...] Read more.
This paper presents a novel analytical approach for the efficient design of a particular class of 2D FIR filters, having a frequency response with an elliptically shaped support in the frequency plane. The filter design is based on a Gaussian shaped prototype filter, which is frequently used in signal and image processing. In order to express the Gaussian prototype frequency response as a trigonometric polynomial, we developed it into a Fourier series up to a specified order, given by the imposed approximation precision. We determined analytically a 1D to 2D frequency transformation, which was applied to the factored frequency response of the prototype, yielding directly the factored frequency response of a directional, elliptically shaped 2D filter, with specified selectivity and an orientation angle. The designed filters have accurate shapes and negligible distortions. We also designed a 2D uniform filter bank of elliptical filters, which was then applied in decomposing a test image into sub-band images, thus proving its usefulness as an analysis filter bank. Then, the original image was accurately reconstructed from its sub-band images. Very selective directional elliptical filters can be used in efficiently extracting straight lines with specified orientations from images, as shown in simulation examples. A computationally efficient implementation at the system level was also discussed, based on a polyphase and block filtering approach. The proposed implementation is illustrated for a smaller size of the filter kernel and input image and is shown to have reduced computational complexity due to its parallel structure, being much more arithmetically efficient compared not only to the direct filtering approach but also with the most recent similar implementations. Full article
(This article belongs to the Section Sensing and Imaging)
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22 pages, 16961 KiB  
Article
Highly Accelerated Dual-Pose Medical Image Registration via Improved Differential Evolution
by Dibin Zhou, Fengyuan Xing, Wenhao Liu and Fuchang Liu
Sensors 2025, 25(15), 4604; https://doi.org/10.3390/s25154604 - 25 Jul 2025
Viewed by 129
Abstract
Medical image registration is an indispensable preprocessing step to align medical images to a common coordinate system before in-depth analysis. The registration precision is critical to the following analysis. In addition to representative image features, the initial pose settings and multiple poses in [...] Read more.
Medical image registration is an indispensable preprocessing step to align medical images to a common coordinate system before in-depth analysis. The registration precision is critical to the following analysis. In addition to representative image features, the initial pose settings and multiple poses in images will significantly affect the registration precision, which is largely neglected in state-of-the-art works. To address this, the paper proposes a dual-pose medical image registration algorithm based on improved differential evolution. More specifically, the proposed algorithm defines a composite similarity measurement based on contour points and utilizes this measurement to calculate the similarity between frontal–lateral positional DRR (Digitally Reconstructed Radiograph) images and X-ray images. In order to ensure the accuracy of the registration algorithm in particular dimensions, the algorithm implements a dual-pose registration strategy. A PDE (Phased Differential Evolution) algorithm is proposed for iterative optimization, enhancing the optimization algorithm’s ability to globally search in low-dimensional space, aiding in the discovery of global optimal solutions. Extensive experimental results demonstrate that the proposed algorithm provides more accurate similarity metrics compared to conventional registration algorithms; the dual-pose registration strategy largely reduces errors in specific dimensions, resulting in reductions of 67.04% and 71.84%, respectively, in rotation and translation errors. Additionally, the algorithm is more suitable for clinical applications due to its lower complexity. Full article
(This article belongs to the Special Issue Recent Advances in X-Ray Sensing and Imaging)
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16 pages, 10372 KiB  
Article
PRONOBIS: A Robotic System for Automated Ultrasound-Based Prostate Reconstruction and Biopsy Planning
by Matija Markulin, Luka Matijević, Janko Jurdana, Luka Šiktar, Branimir Ćaran, Toni Zekulić, Filip Šuligoj, Bojan Šekoranja, Tvrtko Hudolin, Tomislav Kuliš, Bojan Jerbić and Marko Švaco
Robotics 2025, 14(8), 100; https://doi.org/10.3390/robotics14080100 - 22 Jul 2025
Viewed by 173
Abstract
This paper presents the PRONOBIS project, an ultrasound-only, robotically assisted, deep learning-based system for prostate scanning and biopsy treatment planning. The proposed system addresses the challenges of precise prostate segmentation, reconstruction and inter-operator variability by performing fully automated prostate scanning, real-time CNN-transformer-based image [...] Read more.
This paper presents the PRONOBIS project, an ultrasound-only, robotically assisted, deep learning-based system for prostate scanning and biopsy treatment planning. The proposed system addresses the challenges of precise prostate segmentation, reconstruction and inter-operator variability by performing fully automated prostate scanning, real-time CNN-transformer-based image processing, 3D prostate reconstruction, and biopsy needle position planning. Fully automated prostate scanning is achieved by using a robotic arm equipped with an ultrasound system. Real-time ultrasound image processing utilizes state-of-the-art deep learning algorithms with intelligent post-processing techniques for precise prostate segmentation. To create a high-quality prostate segmentation dataset, this paper proposes a deep learning-based medical annotation platform, MedAP. For precise segmentation of the entire prostate sweep, DAF3D and MicroSegNet models are evaluated, and additional image post-processing methods are proposed. Three-dimensional visualization and prostate reconstruction are performed by utilizing the segmentation results and robotic positional data, enabling robust, user-friendly biopsy treatment planning. The real-time sweep scanning and segmentation operate at 30 Hz, which enable complete scan in 15 to 20 s, depending on the size of the prostate. The system is evaluated on prostate phantoms by reconstructing the sweep and by performing dimensional analysis, which indicates 92% and 98% volumetric accuracy on the tested phantoms. Three-dimansional prostate reconstruction takes approximately 3 s and enables fast and detailed insight for precise biopsy needle position planning. Full article
(This article belongs to the Section Sensors and Control in Robotics)
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17 pages, 8708 KiB  
Article
Optimizing Single-Particle Analysis Workflow: Comparative Analysis of the Symmetry Parameter and Particle Quantity upon Reconstruction of the Molecular Complex
by Myeong Seon Jeong, Han-ul Kim, Mi Young An, Yoon Ho Park, Sun Hee Park, Sang J. Chung, Yoon-Sun Yi, Sangmi Jun, Young Kwan Kim and Hyun Suk Jung
Biophysica 2025, 5(3), 30; https://doi.org/10.3390/biophysica5030030 - 22 Jul 2025
Viewed by 110
Abstract
Recent major advancements in cryo-electron microscopy (cryo-EM) have enabled high-resolution structural analysis, accompanied by developments in image processing software packages for single-particle analysis (SPA). SPA facilitates the 3D reconstruction of proteins and macromolecular complexes from numerous individual particles. In this study, we systematically [...] Read more.
Recent major advancements in cryo-electron microscopy (cryo-EM) have enabled high-resolution structural analysis, accompanied by developments in image processing software packages for single-particle analysis (SPA). SPA facilitates the 3D reconstruction of proteins and macromolecular complexes from numerous individual particles. In this study, we systematically evaluated the impact of symmetry parameters and particle quantity on the 3D reconstruction efficiency using the dihydrolipoyl acetyltransferase (E2) inner core of the pyruvate dehydrogenase complex (PDC). We specifically examined how inappropriate symmetry constraints can introduce structural artifacts and distortions, underscoring the necessity for accurate symmetry determination through rigorous validation methods such as directional Fourier shell correlation (FSC) and local-resolution mapping. Additionally, our analysis demonstrates that efficient reconstructions can be achieved with a moderate particle number, significantly reducing computational costs without compromising structural accuracy. We further contextualize these results by discussing recent developments in SPA workflows and hardware optimization, highlighting their roles in enhancing reconstruction accuracy and computational efficiency. Overall, our comprehensive benchmarking provides strategic insights that will facilitate the optimization of SPA experiments, particularly in resource-limited settings, and offers practical guidelines for accurately determining symmetry and particle quantity during cryo-EM data processing. Full article
(This article belongs to the Special Issue Investigations into Protein Structure)
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13 pages, 2438 KiB  
Article
The Integration of Micro-CT Imaging and Finite Element Simulations for Modelling Tooth-Inlay Systems for Mechanical Stress Analysis: A Preliminary Study
by Nikoleta Nikolova, Miryana Raykovska, Nikolay Petkov, Martin Tsvetkov, Ivan Georgiev, Eugeni Koytchev, Roumen Iankov, Mariana Dimova-Gabrovska and Angela Gusiyska
J. Funct. Biomater. 2025, 16(7), 267; https://doi.org/10.3390/jfb16070267 - 21 Jul 2025
Viewed by 371
Abstract
This study presents a methodology for developing and validating digital models of tooth-inlay systems, aiming to trace the complete workflow from clinical procedures to simulation by involving dental professionals—dentists for manual cavity preparation and dental technicians for restoration modelling—while integrating micro-computed tomography (micro-CT) [...] Read more.
This study presents a methodology for developing and validating digital models of tooth-inlay systems, aiming to trace the complete workflow from clinical procedures to simulation by involving dental professionals—dentists for manual cavity preparation and dental technicians for restoration modelling—while integrating micro-computed tomography (micro-CT) imaging with finite element analysis (FEA). The proposed workflow includes (1) the acquisition of high-resolution 3D micro-CT scans of a non-restored tooth, (2) image segmentation and reconstruction to create anatomically accurate digital twins and mesh generation, (3) the selection of proper resin and the 3D printing of four typodonts, (4) the manual preparation of cavities on the typodonts, (5) the acquisition of high-resolution 3D micro-CT scans of the typodonts, (6) mesh generation, digital inlay and onlay modelling and material property assignment, and (7) nonlinear FEA simulations under representative masticatory loading. The approach enables the visualisation of stress and deformation patterns, with preliminary results indicating stress concentrations at the tooth-restoration interface integrating different cavity alternatives and restorations on the same tooth. Quantitative outputs include von Mises stress, strain energy density, and displacement distribution. This study demonstrates the feasibility of using image-based, tooth-specific digital twins for biomechanical modelling in dentistry. The developed framework lays the groundwork for future investigations into the optimisation of restoration design and material selection in clinical applications. Full article
(This article belongs to the Section Dental Biomaterials)
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21 pages, 2522 KiB  
Article
Using Convolutional Neural Networks and Pattern Matching for Digitization of Printed Circuit Diagrams
by Lukas Fuchs, Marc Diesse, Matthias Weber, Arif Rasim, Julian Feinauer and Volker Schmidt
Electronics 2025, 14(14), 2889; https://doi.org/10.3390/electronics14142889 - 19 Jul 2025
Viewed by 223
Abstract
The efficient and reliable maintenance and repair of industrial machinery depend critically on circuit diagrams, which serve as essential references for troubleshooting and must be updated when machinery is modified. However, many circuit diagrams are not available in structured, machine-readable format; instead, they [...] Read more.
The efficient and reliable maintenance and repair of industrial machinery depend critically on circuit diagrams, which serve as essential references for troubleshooting and must be updated when machinery is modified. However, many circuit diagrams are not available in structured, machine-readable format; instead, they often exist as unstructured PDF files, rendered images, or even photographs. Existing digitization methods often address isolated tasks, such as symbol detection, but fail to provide a comprehensive solution. This paper presents a novel pipeline for extracting the underlying graph structures of circuit diagrams, integrating image preprocessing, pattern matching, and graph extraction. A U-net model is employed for noise removal, followed by gray-box pattern matching for device classification, line detection by morphological operations, and a final graph extraction step to reconstruct circuit connectivity. A detailed error analysis highlights the strengths and limitations of each pipeline component. On a skewed test diagram from a scan with slight rotation, the proposed pipeline achieved a device detection accuracy of 88.46% with no false positives and a line detection accuracy of 94.7%. Full article
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27 pages, 90509 KiB  
Article
A Phishing Software Detection Approach Based on R-Tree and the Analysis of the Edge of Stability Phenomenon
by Licheng Ao, Yifeng Lin and Yuer Yang
Electronics 2025, 14(14), 2862; https://doi.org/10.3390/electronics14142862 - 17 Jul 2025
Viewed by 297
Abstract
With the rapid development of science and technology, attackers have invented more and more ways to hide malicious information. Hidden malicious information often contains a large number of malicious codes and malicious scripts, which can be hidden in legitimate software and reconstructed to [...] Read more.
With the rapid development of science and technology, attackers have invented more and more ways to hide malicious information. Hidden malicious information often contains a large number of malicious codes and malicious scripts, which can be hidden in legitimate software and reconstructed to be executed as the software is executed. In recent years, phishing software has become popular at home and abroad, causing fraud to occur frequently. Among various carriers with high redundancy, images are often used by attackers to hide malicious information because they are often used as information transmission carriers and highly redundant storage. This paper aims to explore how attackers hide malicious information in images and use a convolutional neural network (CNN) framework with acceleration based on the analysis of the Edge of Stability (EOS) phenomenon to detect mobile phishing software. To design a machine learning approach to solve the problem, we summarize the characteristics of nine presented mainstream malicious information hiding methods and present a CNN framework that maintains a high initial learning rate while preventing the gradient from exploding in EOS. R-tree is used to speed up the search for nearby pixels that contain malicious information. The CNN model generated by training under this framework can reach an accuracy of 98.53% and has been well implemented in mobile terminals. Full article
(This article belongs to the Special Issue Machine Learning Approaches for Natural Language Processing)
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19 pages, 3064 KiB  
Article
HR-pQCT and 3D Printing for Forensic and Orthopaedic Analysis of Gunshot-Induced Bone Damage
by Richard Andreas Lindtner, Lukas Kampik, Werner Schmölz, Mateus Enzenberg, David Putzer, Rohit Arora, Bettina Zelger, Claudia Wöss, Gerald Degenhart, Christian Kremser, Michaela Lackner, Anton Kasper Pallua, Michael Schirmer and Johannes Dominikus Pallua
Biomedicines 2025, 13(7), 1742; https://doi.org/10.3390/biomedicines13071742 - 16 Jul 2025
Viewed by 229
Abstract
Background/Objectives: Recent breakthroughs in three-dimensional (3D) printing and high-resolution imaging have opened up new possibilities in personalized medicine, surgical planning, and forensic reconstruction. This study breaks new ground by evaluating the integration of high-resolution peripheral quantitative computed tomography (HR-pQCT) with multimodal imaging and [...] Read more.
Background/Objectives: Recent breakthroughs in three-dimensional (3D) printing and high-resolution imaging have opened up new possibilities in personalized medicine, surgical planning, and forensic reconstruction. This study breaks new ground by evaluating the integration of high-resolution peripheral quantitative computed tomography (HR-pQCT) with multimodal imaging and additive manufacturing to assess a chronic, infected gunshot injury in the knee joint of a red deer. This unique approach serves as a translational model for complex skeletal trauma. Methods: Multimodal imaging—including clinical CT, MRI, and HR-pQCT—was used to characterise the extent of osseous and soft tissue damage. Histopathological and molecular analyses were performed to confirm the infectious agent. HR-pQCT datasets were segmented and processed for 3D printing using PolyJet, stereolithography (SLA), and fused deposition modelling (FDM). Printed models were quantitatively benchmarked through 3D surface deviation analysis. Results: Imaging revealed comminuted fractures, cortical and trabecular degradation, and soft tissue involvement, consistent with chronic osteomyelitis. Sphingomonas sp., a bacterium that forms biofilms, was identified as the pathogen. Among the printing methods, PolyJet and SLA demonstrated the highest anatomical accuracy, whereas FDM exhibited greater geometric deviation. Conclusions: HR-pQCT-guided 3D printing provides a powerful tool for the anatomical visualisation and quantitative assessment of complex bone pathology. This approach not only enhances diagnostic precision but also supports applications in surgical rehearsal and forensic analysis. It illustrates the potential of digital imaging and additive manufacturing to advance orthopaedic and trauma care, inspiring future research and applications in the field. Full article
(This article belongs to the Section Biomedical Engineering and Materials)
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22 pages, 13424 KiB  
Article
Measurement of Fracture Networks in Rock Sample by X-Ray Tomography, Convolutional Filtering and Deep Learning
by Alessia Caputo, Maria Teresa Calcagni, Giovanni Salerno, Elisa Mammoliti and Paolo Castellini
Sensors 2025, 25(14), 4409; https://doi.org/10.3390/s25144409 - 15 Jul 2025
Viewed by 341
Abstract
This study presents a comprehensive methodology for the detection and characterization of fractures in geological samples using X-ray computed tomography (CT). By combining convolution-based image processing techniques with advanced neural network-based segmentation, the proposed approach achieves high precision in identifying complex fracture networks. [...] Read more.
This study presents a comprehensive methodology for the detection and characterization of fractures in geological samples using X-ray computed tomography (CT). By combining convolution-based image processing techniques with advanced neural network-based segmentation, the proposed approach achieves high precision in identifying complex fracture networks. The method was applied to a marly limestone sample from the Maiolica Formation, part of the Umbria–Marche stratigraphic succession (Northern Apennines, Italy), a geological context where fractures often vary in size and contrast and are frequently filled with minerals such as calcite or clays, making their detection challenging. A critical part of the work involved addressing multiple sources of uncertainty that can impact fracture identification and measurement. These included the inherent spatial resolution limit of the CT system (voxel size of 70.69 μm), low contrast between fractures and the surrounding matrix, artifacts introduced by the tomographic reconstruction process (specifically the Radon transform), and noise from both the imaging system and environmental factors. To mitigate these challenges, we employed a series of preprocessing steps such as Gaussian and median filtering to enhance image quality and reduce noise, scanning from multiple angles to improve data redundancy, and intensity normalization to compensate for shading artifacts. The neural network segmentation demonstrated superior capability in distinguishing fractures filled with various materials from the host rock, overcoming the limitations observed in traditional convolution-based methods. Overall, this integrated workflow significantly improves the reliability and accuracy of fracture quantification in CT data, providing a robust and reproducible framework for the analysis of discontinuities in heterogeneous and complex geological materials. Full article
(This article belongs to the Section Sensing and Imaging)
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24 pages, 14668 KiB  
Article
Metric Error Assessment Regarding Geometric 3D Reconstruction of Transparent Surfaces via SfM Enhanced by 2D and 3D Gaussian Splatting
by Dario Billi, Gabriella Caroti and Andrea Piemonte
Sensors 2025, 25(14), 4410; https://doi.org/10.3390/s25144410 - 15 Jul 2025
Viewed by 528
Abstract
This research investigates the metric accuracy of 3D transparent object reconstruction, a task where conventional photogrammetry often fails. The topic is especially relevant in cultural heritage (CH), where accurate digital documentation of glass and transparent artifacts is important. The work proposes a practical [...] Read more.
This research investigates the metric accuracy of 3D transparent object reconstruction, a task where conventional photogrammetry often fails. The topic is especially relevant in cultural heritage (CH), where accurate digital documentation of glass and transparent artifacts is important. The work proposes a practical methodology using existing tools to verify metric accuracy standards. The study compares three methods, conventional photogrammetry, 3D Gaussian splatting (3DGS), and 2D Gaussian splatting (2DGS), to assess their ability to produce complete and metrically reliable 3D models suitable for measurement and geometric analysis. A transparent glass artifact serves as the case study. Results show that 2DGS captures fine surface and internal details with better geometric consistency than 3DGS and photogrammetry. Although 3DGS offers high visual quality, it introduces surface artifacts that affect metric reliability. Photogrammetry fails to reconstruct the object entirely. The study highlights that visual quality does not ensure geometric accuracy, which is critical for measurement applications. In this work, ground truth comparisons confirm that 2DGS offers the best trade-off between accuracy and appearance, despite higher computational demands. These findings suggest extending the experimentation to other sets of images featuring transparent objects, and possibly also reflective ones. Full article
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21 pages, 3456 KiB  
Article
Precision in 3D: A Fast and Accurate Algorithm for Reproducible Motoneuron Structure and Protein Expression Analysis
by Morgan Highlander, Shelby Ward, Bradley LeHoty, Teresa Garrett and Sherif Elbasiouny
Bioengineering 2025, 12(7), 761; https://doi.org/10.3390/bioengineering12070761 - 14 Jul 2025
Viewed by 265
Abstract
Structural analysis of motoneuron somas and their associated proteins via immunohistochemistry (IHC) remains tedious and subjective, requiring costly software or adapted 2D manual methods that lack reproducibility and analytical rigor. Yet, neurodegenerative disease and aging research demands precise structural comparisons to elucidate mechanisms [...] Read more.
Structural analysis of motoneuron somas and their associated proteins via immunohistochemistry (IHC) remains tedious and subjective, requiring costly software or adapted 2D manual methods that lack reproducibility and analytical rigor. Yet, neurodegenerative disease and aging research demands precise structural comparisons to elucidate mechanisms driving neuronal degeneration. To address this need, we developed a novel algorithm that automates repetitive and subjective IHC analysis tasks, enabling thorough, objective, blinded, order-agnostic, and reproducible 3D batch analysis. With no manual tracing, the algorithm produces 3D Cartesian reconstructions of motoneuron somas from 60× IHC images of mouse lumbar spinal tissue. From these reconstructions, it measures 3D soma volume and efficiently quantitates net somatic protein expression and macro-cluster size. In this validation study, we applied the algorithm to assess soma size and C-bouton expression in various healthy control mice, comparing its measurements against manual measurements and across multiple algorithm users to confirm its accuracy and reproducibility. This novel, customizable tool enables efficient and high-fidelity 3D motoneuron analysis, replacing tedious, qualitative, cell-by-cell manual tuning with automatic threshold adaptation and quantified batch settings. For the first time, we attain reproducible results with quantifiable accuracy, exhaustive sampling, and a high degree of objectivity. Full article
(This article belongs to the Special Issue Data Modeling and Algorithms in Biomedical Applications)
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16 pages, 5262 KiB  
Article
A Hybrid Framework for Metal Artifact Suppression in CT Imaging of Metal Lattice Structures via Radon Transform and Attention-Based Super-Resolution Reconstruction
by Bingyang Wang, Zhiwei Zhang, Heng Li and Ronghai Wu
Appl. Sci. 2025, 15(14), 7819; https://doi.org/10.3390/app15147819 - 11 Jul 2025
Viewed by 219
Abstract
High-density component-induced metal artifacts in industrial computed tomography (CT) severely impair image quality and make further analysis more difficult. To suppress artifacts and improve image quality, this research suggests a practical approach that combines lightweight attention-enhanced super-resolution networks with Radon-domain artifact elimination. First, [...] Read more.
High-density component-induced metal artifacts in industrial computed tomography (CT) severely impair image quality and make further analysis more difficult. To suppress artifacts and improve image quality, this research suggests a practical approach that combines lightweight attention-enhanced super-resolution networks with Radon-domain artifact elimination. First, the original CT slices are subjected to bicubic interpolation, which enhances resolution and reduces sampling errors during transformation. The Radon transform, which detects and suppresses metal artifacts in the Radon domain, is then used to convert the interpolated pictures into sinograms. The artifact-suppressed sinograms are then reconstructed at better resolution using a lightweight Enhanced Deep Super-Resolution (EDSR) network with a channel attention mechanism, which consists of only one residual block. The inverse Radon transform is used to recreate the final CT images. An average peak signal-to-noise ratio (PSNR) of 40.39 dB and an average signal-to-noise ratio (SNR) of 29.75 dB, with an SNR improvement of 15.48 dB over the original artifact-laden images, show the success of the suggested strategy in experiments. This method offers a workable and effective way to improve image quality in industrial CT applications that involve intricate structures that incorporate metal. Full article
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14 pages, 2707 KiB  
Article
Implantation of an Artificial Intelligence Denoising Algorithm Using SubtlePET™ with Various Radiotracers: 18F-FDG, 68Ga PSMA-11 and 18F-FDOPA, Impact on the Technologist Radiation Doses
by Jules Zhang-Yin, Octavian Dragusin, Paul Jonard, Christian Picard, Justine Grangeret, Christopher Bonnier, Philippe P. Leveque, Joel Aerts and Olivier Schaeffer
J. Imaging 2025, 11(7), 234; https://doi.org/10.3390/jimaging11070234 - 11 Jul 2025
Viewed by 225
Abstract
This study assesses the clinical deployment of SubtlePET™, a commercial AI-based denoising algorithm, across three radiotracers—18F-FDG, 68Ga-PSMA-11, and 18F-FDOPA—with the goal of improving image quality while reducing injected activity, technologist radiation exposure, and scan time. A retrospective analysis on [...] Read more.
This study assesses the clinical deployment of SubtlePET™, a commercial AI-based denoising algorithm, across three radiotracers—18F-FDG, 68Ga-PSMA-11, and 18F-FDOPA—with the goal of improving image quality while reducing injected activity, technologist radiation exposure, and scan time. A retrospective analysis on a digital PET/CT system showed that SubtlePET™ enabled dose reductions exceeding 33% and time savings of over 25%. AI-enhanced images were rated interpretable in 100% of cases versus 65% for standard low-dose reconstructions. Notably, 85% of AI-enhanced scans received the maximum Likert quality score (5/5), indicating excellent diagnostic confidence and noise suppression, compared to only 50% with conventional reconstruction. The quantitative image quality improved significantly across all tracers, with SNR and CNR gains of 50–70%. Radiotracer dose reductions were particularly substantial in low-BMI patients (up to 41% for FDG), and the technologist exposure decreased for high-exposure roles. The daily patient throughput increased by an average of 4.84 cases. These findings support the robust integration of SubtlePET™ into routine clinical PET practice, offering improved efficiency, safety, and image quality without compromising lesion detectability. Full article
(This article belongs to the Section Medical Imaging)
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17 pages, 8301 KiB  
Article
Composites of Pea Protein Nanofibril and Epigallocatechin Gallate: Formation Mechanism, Structural Characterization, and Antioxidant Activity
by Hailing Zhang, Yangxuan Yang, Yuting Fan and Jiang Yi
Foods 2025, 14(14), 2418; https://doi.org/10.3390/foods14142418 - 9 Jul 2025
Viewed by 262
Abstract
The EGCG/PPN composite, prepared by combining pea protein nanofibrils (PPNs) with epigallocatechin gallate (EGCG), could be used as a multifunctional nanocarrier. Compared to pea protein isolate (PPI), EGCG/PPN composites exhibited remarkably higher turbidity and zeta potential, along with similar UV spectra. Intrinsic fluorescence [...] Read more.
The EGCG/PPN composite, prepared by combining pea protein nanofibrils (PPNs) with epigallocatechin gallate (EGCG), could be used as a multifunctional nanocarrier. Compared to pea protein isolate (PPI), EGCG/PPN composites exhibited remarkably higher turbidity and zeta potential, along with similar UV spectra. Intrinsic fluorescence spectroscopy, ThT fluorescence spectroscopy, and surface hydrophobicity analysis suggested that the interactions between EGCG and PPN were primarily driven by hydrophobic forces. UV spectra indicated that the microenvironment of amino acid residues in the tertiary structure of the protein changes upon complexation, and circular dichroism (CD) revealed that the incorporation of EGCG increases the β-sheet content in the protein’s secondary structure. Analyses of DPPH and ABTS radical scavenging activity, as well as reducing power, demonstrated that the synergistic effect between EGCG and PPN did not hinder the inherent antioxidant properties of EGCG but rather enhanced them significantly. Transmission electron microscopy (TEM) images showed that the addition of EGCG reconstructed the fibril morphology, thereby affecting the properties of PPNs. Overall, the composite fabricated through the interaction between PPN and EGCG shows great potential as a nanocarrier in the processing of functional foods. Full article
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