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208 Results Found

  • Article
  • Open Access
21 Citations
6,010 Views
12 Pages

14 December 2021

Adverse childhood experiences (ACEs) are associated with poor mental health. Emerging research demonstrates the protective role of positive childhood experiences, including a positive sense of self and relationships with both humans and animals, in m...

  • Article
  • Open Access
17 Citations
5,011 Views
19 Pages

The Long-Term Health and Human Capital Consequences of Adverse Childhood Experiences in the Birth to Thirty Cohort: Single, Cumulative, and Clustered Adversity

  • Sara N. Naicker,
  • Marilyn N. Ahun,
  • Sahba Besharati,
  • Shane A. Norris,
  • Massimiliano Orri and
  • Linda M. Richter

Human capital—that is the cumulative abilities, education, social skills, and mental and physical health one possesses—is increasingly recognized as key to the reduction of inequality in societies. Adverse childhood experiences have been...

  • Article
  • Open Access
14 Citations
11,395 Views
15 Pages

16 February 2023

Early childhood is a time of rapid physiological, cognitive, and social development, affected by various environmental factors. The physical environment, including the environmental microbiome (the entire consortium of microorganisms and their theatr...

  • Article
  • Open Access
8 Citations
3,318 Views
12 Pages

Bisphenol A and S in the Urine of Newborns: Plastic for Non-Food Use Still without Rules

  • Valeria Bellisario,
  • Enrico Cocchi,
  • Roberta Tassinari,
  • Giulia Squillacioti,
  • Tiziana Musso,
  • Stefano Sottemano,
  • Michael Zorzi,
  • Paola Dalmasso,
  • Alessandra Coscia and
  • Roberto Bono
  • + 1 author

3 March 2021

The aim of the present study was to assess the effects of bisphenol (BP) exposure on pregnancy and neonatal life. We have (a) determined BP (BPA and BPS) concentration levels in a group of newborns and their mothers; (b) identified factors, habits, a...

  • Article
  • Open Access
20 Citations
9,914 Views
15 Pages

Uncovering the Drivers of Childhood Immunization Inequality with Caregivers, Community Members and Health System Stakeholders: Results from a Human-Centered Design Study in DRC, Mozambique and Nigeria

  • Jessica C. Shearer,
  • Olivia Nava,
  • Wendy Prosser,
  • Saira Nawaz,
  • Salva Mulongo,
  • Thérèse Mambu,
  • Eric Mafuta,
  • Khatia Munguambe,
  • Betuel Sigauque and
  • Grace Chee
  • + 10 authors

17 March 2023

Background: The importance of immunization for child survival underscores the need to eliminate immunization inequalities. Few existing studies of inequalities use approaches that view the challenges and potential solutions from the perspective of ca...

  • Article
  • Open Access
6 Citations
3,560 Views
26 Pages

Spatiotemporal Analysis of PM2.5 Concentrations on the Incidence of Childhood Asthma in Developing Countries: Case Study of Cartagena de Indias, Colombia

  • José Antonio Álvarez Aldegunde,
  • Adrián Fernández Sánchez,
  • Manuel Saba,
  • Edgar Quiñones Bolaños and
  • Luis R. Caraballo

29 August 2022

The increase in airborne pollution in large cities since the mid-20th century has had a physiologically proven impact on respiratory health, resulting in the irritation and corrosion of the alveolar wall. One of the demographics of the population mos...

  • Review
  • Open Access
17 Citations
8,298 Views
24 Pages

Beneficial Effects of Plant Extracts and Bioactive Food Components in Childhood Supplementation

  • Hammad Ullah,
  • Anna De Filippis,
  • Alessandra Baldi,
  • Marco Dacrema,
  • Cristina Esposito,
  • Emanuele Ugo Garzarella,
  • Cristina Santarcangelo,
  • Ariyawan Tantipongpiradet and
  • Maria Daglia

10 September 2021

The pivotal role of childhood nutrition has always roused a growing interest from the scientific community. Plant extracts and bioactive dietary components play a significant role in the maintenance of human health and wellness, with the potential to...

  • Article
  • Open Access
1,760 Views
11 Pages

Primary Healthcare Professionals’ Knowledge and Attitudes Towards Meningococcal, Rotavirus, and HPV Vaccines in Children and Adolescents

  • Eren Yıldız,
  • Rukiye Ünsal Saç,
  • Hilmi Onur Kabukçu,
  • Fethiye Yıldız,
  • Funda Çatan İnan and
  • Medine Ayşin Taşar

Aim: This study aimed to evaluate the knowledge and attitudes of family physicians and family health personnel who are responsible for childhood vaccination services in primary care regarding meningococcal, rotavirus, and human papillomavirus vaccine...

  • Review
  • Open Access
2 Citations
5,629 Views
22 Pages

Terrestrial Animal Source Foods and Health Outcomes for Those with Special Nutrient Needs in the Life Course

  • Lora Iannotti,
  • Ana María Rueda García,
  • Giulia Palma,
  • Fanette Fontaine,
  • Beate Scherf,
  • Lynnette M. Neufeld,
  • Rachel Zimmerman and
  • Patrizia Fracassi

24 September 2024

Background. Animal source foods are under scrutiny for their role in human health, yet some nutritionally vulnerable populations are largely absent from consideration. Methods. Applying a Population Intervention/Exposure Comparator Outcome (PICO/PECO...

  • Systematic Review
  • Open Access
22 Citations
7,063 Views
28 Pages

The Gut Microbiome in Early Life Stress: A Systematic Review

  • Ana Agusti,
  • Femke Lamers,
  • Maria Tamayo,
  • Carlos Benito-Amat,
  • Gara V. Molina-Mendoza,
  • Brenda W. J. H. Penninx and
  • Yolanda Sanz

30 May 2023

Exposure to early life stress (ELS), prenatal or postnatal during childhood and adolescence, can significantly impact mental and physical health. The role of the intestinal microbiome in human health, and particularly mental health, is becoming incre...

  • Article
  • Open Access
12 Citations
4,791 Views
13 Pages

Religiosity and spirituality (R/S) and some of their specific aspects are associated with health. A negatively perceived relationship with God, which has adverse health outcomes, can be formed by human attachment both in childhood and adulthood. The...

  • Commentary
  • Open Access
1 Citations
3,902 Views
3 Pages

31 August 2017

There is a growing threat in the re-emergence of diseases that impact pediatric demographics. While major strides have been made in the field of childhood cancers, there are still more questions than answers. In addition, public resistance to recomme...

  • Review
  • Open Access
2 Citations
3,654 Views
15 Pages

Obesogens in Adolescence: Challenging Aspects and Prevention Strategies

  • Marina Nicolaou,
  • Meropi Toumba,
  • Alexandros Kythreotis,
  • Habib Daher and
  • Nicos Skordis

Childhood obesity has become a global epidemic, with significant increases in prevalence over recent decades. While excessive calorie consumption and physical inactivity are known factors, emerging research highlights the role of endocrine-disrupting...

  • Article
  • Open Access
116 Citations
37,370 Views
15 Pages

Childhood Attachment to Pets: Associations between Pet Attachment, Attitudes to Animals, Compassion, and Humane Behaviour

  • Roxanne D. Hawkins,
  • Joanne M. Williams and
  • Scottish Society for the Prevention of Cruelty to Animals (Scottish SPCA)

Attachment to pets has an important role in children’s social, emotional, and cognitive development, mental health, well-being, and quality of life. This study examined associations between childhood attachment to pets and caring and friendship behav...

  • Article
  • Open Access
32 Citations
8,522 Views
16 Pages

Breastmilk Feeding during the First 4 to 6 Months of Age and Childhood Disease Burden until 10 Years of Age

  • Ju Hee Kim,
  • Seung Won Lee,
  • Jung Eun Lee,
  • Eun Kyo Ha,
  • Man Yong Han and
  • Eun Lee

17 August 2021

Background: Breastfeeding is recommended due to its beneficial effects on human health. However, the effect of breastfeeding on health differs, resulting in various childhood diseases. Objective: Our purpose was to investigate the association between...

  • Article
  • Open Access
29 Citations
8,891 Views
16 Pages

Viral Etiologies of Acute Dehydrating Gastroenteritis in Pakistani Children: Confounding Role of Parechoviruses

  • Muhammad Masroor Alam,
  • Adnan Khurshid,
  • Shahzad Shaukat,
  • Muhammad Suleman Rana,
  • Salmaan Sharif,
  • Mehar Angez,
  • Nadia Nisar,
  • Uzma Bashir Aamir,
  • Muhammad Naeem and
  • Syed Sohail Zahoor Zaidi

20 January 2015

Despite substantial interventions in the understanding and case management of acute gastroenteritis, diarrheal diseases are still responsible for a notable amount of childhood deaths. Although the rotavirus is known to cause a considerable burden of...

  • Feature Paper
  • Review
  • Open Access
43 Citations
9,042 Views
9 Pages

Breastfeeding and Allergic Diseases: What’s New?

  • Giulia Nuzzi,
  • Maria Elisa Di Cicco and
  • Diego Giampietro Peroni

24 April 2021

Asthma and other allergic disorders, such as atopic dermatitis and food allergies, are common chronic health problems in childhood. The rapid rise in the prevalence of these conditions registered over the last few decades has stressed the need to ide...

  • Review
  • Open Access
8 Citations
4,841 Views
17 Pages

Early Life Adversity, Microbiome, and Inflammatory Responses

  • Eléonore Beurel and
  • Charles B. Nemeroff

Early life adversity has a profound impact on physical and mental health. Because the central nervous and immune systems are not fully mature at birth and continue to mature during the postnatal period, a bidirectional interaction between the central...

  • Essay
  • Open Access
5,179 Views
18 Pages

Music and Arts in Early Childhood Education: Paths for Professional Development Towards Social and Human Development

  • Helena Rodrigues,
  • Ana Isabel Pereira,
  • Paulo Maria Rodrigues,
  • Paulo Ferreira Rodrigues and
  • Angelita Broock

4 August 2025

This article examines training itineraries for early childhood education professionals in Portugal, focusing on promoting social and human development through music and the arts for infants. The training models discussed are categorized as short-term...

  • Proceeding Paper
  • Open Access
1,610 Views
12 Pages

“Animals Are My Friends”: Exploring the Relationship Between Animal Companionship in Childhood and Moral Concerns in Adulthood

  • Léa Berger-Meunier,
  • David S. Smith,
  • Nathalie Marec-Breton and
  • Nathalie Bonneton-Botté

Research on human–animal relationships suggests that close bonds with animals can enhance empathy, reduce speciesism, and improve human physical and psychological health. This study investigated whether pet ownership—particularly attachme...

  • Article
  • Open Access
7 Citations
2,727 Views
10 Pages

Early Childhood Stimulating Environment Predicts Later Childhood Resilience in an Indian Longitudinal Birth Cohort Study

  • Beena Koshy,
  • Manikandan Srinivasan,
  • Sowmiya Gopalakrishnan,
  • Venkata Raghava Mohan,
  • Rebecca Scharf,
  • Sushil John,
  • Rachel Beulah,
  • Jayaprakash Muliyil and
  • Gagandeep Kang

9 November 2022

Background: Human resilience is dynamic and generated through myriad interactions starting from early childhood. Resilience can improve quality of life and longevity. Objective: The current analysis evaluates childhood resilience at 9 years of age an...

  • Review
  • Open Access
25 Citations
22,851 Views
19 Pages

Human Papillomavirus Infection during Pregnancy and Childhood: A Comprehensive Review

  • Ali Ardekani,
  • Erfan Taherifard,
  • Abolfazl Mollalo,
  • Emadeddin Hemadi,
  • Amirhossein Roshanshad,
  • Reza Fereidooni,
  • Safoura Rouholamin,
  • Mahroo Rezaeinejad,
  • Maryam Farid-Mojtahedi and
  • Ali Rostami
  • + 1 author

Human papillomavirus (HPV), the most prevalent sexually transmitted disease worldwide, is the causative agent for several genital and oropharyngeal cancers and a suspected agent for many malignancies. HPV is associated with several adverse health out...

  • Article
  • Open Access
33 Citations
12,084 Views
18 Pages

A body of empirical research has revealed that prenatal exposure to tobacco smoke is related to a host of negative outcomes, including reduced cognitive abilities, later-life health problems, and childhood behavioral problems. While these findings ar...

  • Systematic Review
  • Open Access
17 Citations
12,897 Views
23 Pages

28 December 2022

Early social and emotional development is foundational for children’s health, education, well-being, and later adjustment in society. It is also a cornerstone of positive psychology—the exploration of human flourishing at an individual, c...

  • Review
  • Open Access
154 Citations
49,335 Views
25 Pages

Effects of Dietary Phytoestrogens on Hormones throughout a Human Lifespan: A Review

  • Inés Domínguez-López,
  • Maria Yago-Aragón,
  • Albert Salas-Huetos,
  • Anna Tresserra-Rimbau and
  • Sara Hurtado-Barroso

15 August 2020

Dietary phytoestrogens are bioactive compounds with estrogenic activity. With the growing popularity of plant-based diets, the intake of phytoestrogen-rich legumes (especially soy) and legume-derived foods has increased. Evidence from preclinical stu...

  • Review
  • Open Access
14 Citations
11,776 Views
34 Pages

Enduring Neurobiological Consequences of Early-Life Stress: Insights from Rodent Behavioral Paradigms

  • Luisa Speranza,
  • Kardelen Dalim Filiz,
  • Pellegrino Lippiello,
  • Maria Grazia Ferraro,
  • Silvia Pascarella,
  • Maria Concetta Miniaci and
  • Floriana Volpicelli

Stress profoundly affects physical and mental health, particularly when experienced early in life. Early-life stress (ELS) encompasses adverse childhood experiences such as abuse, neglect, violence, or chronic poverty. These stressors can induce long...

  • Article
  • Open Access
38 Citations
6,886 Views
19 Pages

22 October 2021

Background: Vaccines are among the most effective and cost-efficient public health interventions for promoting child health. However, uptake is considerably affected by vaccine hesitancy. An example is Malawi, with a decline in second vaccine doses a...

  • Commentary
  • Open Access
474 Citations
85,899 Views
16 Pages

Resilience in Children: Developmental Perspectives

  • Ann S. Masten and
  • Andrew J. Barnes

Advances in developmental resilience science are highlighted with commentary on implications for pediatric systems that aspire to promote healthy development over the life course. Resilience science is surging along with growing concerns about the co...

  • Article
  • Open Access
89 Citations
20,628 Views
26 Pages

Family Pet Ownership during Childhood: Findings from a UK Birth Cohort and Implications for Public Health Research

  • Carri Westgarth,
  • Jon Heron,
  • Andy R. Ness,
  • Peter Bundred,
  • Rosalind M. Gaskell,
  • Karen P. Coyne,
  • Alexander J. German,
  • Sandra McCune and
  • Susan Dawson

In developed nations, approximately half of household environments contain pets. Studies of Human-Animal Interaction (HAI) have proposed that there are health benefits and risks associated with pet ownership. However, accurately demonstrating and und...

  • Review
  • Open Access
17 Citations
7,064 Views
18 Pages

Nutritional Programming: History, Hypotheses, and the Role of Prenatal Factors in the Prevention of Metabolic Diseases—A Narrative Review

  • Izabela Michońska,
  • Edyta Łuszczki,
  • Magdalena Zielińska,
  • Łukasz Oleksy,
  • Artur Stolarczyk and
  • Katarzyna Dereń

21 October 2022

Childhood obesity and the numerous lifestyle diseases associated with it are undoubtedly among the key problems in modern medicine and public health. However, this problem concerns not only the present or immediate future, but also the longer term. A...

  • Review
  • Open Access
12 Citations
8,906 Views
41 Pages

Early Roots of Childhood Obesity: Risk Factors, Mechanisms, and Prevention Strategies

  • Giuseppina Rosaria Umano,
  • Simonetta Bellone,
  • Raffaele Buganza,
  • Valeria Calcaterra,
  • Domenico Corica,
  • Luisa De Sanctis,
  • Anna Di Sessa,
  • Maria Felicia Faienza,
  • Nicola Improda and
  • Maria Elisabeth Street
  • + 6 authors

Childhood obesity is a growing global health concern, with established links to physical activity, nutrition, and, increasingly, to prenatal and perinatal factors. Emerging evidence highlights the significant role of maternal conditions such as obesi...

  • Review
  • Open Access
222 Citations
104,737 Views
25 Pages

Companion Animals and Child/Adolescent Development: A Systematic Review of the Evidence

  • Rebecca Purewal,
  • Robert Christley,
  • Katarzyna Kordas,
  • Carol Joinson,
  • Kerstin Meints,
  • Nancy Gee and
  • Carri Westgarth

Childhood and adolescence are important developmental phases which influence health and well-being across the life span. Social relationships are fundamental to child and adolescent development; yet studies have been limited to children’s relationshi...

  • Review
  • Open Access
2 Citations
7,994 Views
25 Pages

This article describes two contesting paradigms of urban planning employed successively in Portland, Oregon; (1) urban planning typical of the US in the first half of the 20th Century that was focused on traffic and infrastructure, and (2) progressiv...

  • Review
  • Open Access
8 Citations
2,996 Views
20 Pages

Influence of Adipose Tissue on Early Metabolic Programming: Conditioning Factors and Early Screening

  • Maria Puche-Juarez,
  • Juan M. Toledano,
  • Julio J. Ochoa,
  • Javier Diaz-Castro and
  • Jorge Moreno-Fernandez

Background: Obesity and being overweight have become one of the world’s most severe health issues, not only because of the pathology but also because of the development of related comorbidities. Even when children reach adulthood, the mother&rs...

  • Systematic Review
  • Open Access
712 Views
15 Pages

18 September 2025

Early childhood care (ECC) represents a vital service for the families two supports; however, research on the experiences of young professionals working in this field is lacking. The nature of the work is inherently difficult due to lengthy bureaucra...

  • Article
  • Open Access
1 Citations
1,934 Views
21 Pages

Exploring Technology Integration in Health and Safety Routines in a Shanghai Kindergarten

  • Wenwei Luo,
  • Xiaoyu Wu,
  • Ilene R. Berson,
  • Michael J. Berson,
  • Huihua He and
  • Minqi Gao

22 January 2025

Background: Digital technology is increasingly being used in early childhood education; however, there is a significant gap in understanding how these technologies are practiced in health and safety routines. Objective: This study aims to understand...

  • Article
  • Open Access
2 Citations
2,626 Views
15 Pages

Transgenerational Cycle of Traumatization and HIV Risk Exposure among Crack Users

  • Joana Corrêa de Magalhães Narvaez,
  • Vinícius Serafini Roglio,
  • Brittany Di Tommaso and
  • Flavio Pechansky

The aim of this manuscript is to understand the impact of childhood sexual abuse on the development of Post-Traumatic Stress Disorder (PTSD), Human Immunodeficiency Virus (HIV) exposure. and parental neglect in crack cocaine users, considering the ro...

  • Editorial
  • Open Access
4 Citations
5,872 Views
3 Pages

Vaccine Hesitancy in Children—A Call for Action

  • Annabelle De St. Maurice and
  • Kathryn M. Edwards

Immunizations have made an enormous impact on the health of children by decreasing childhood morbidity and mortality from a variety of vaccine-preventable diseases worldwide. The eradication of polio from Nigeria and India is one of the most recent v...

  • Article
  • Open Access
4 Citations
2,759 Views
13 Pages

Child marriage, which the UN’s Sustainable Development Goal seeks to eliminate by 2030, represents a violation of the human rights of children. These concerns are driven by the negative impact of child marriage on the health of children married...

  • Review
  • Open Access
4 Citations
2,939 Views
21 Pages

Neonatal Gut Mycobiome: Immunity, Diversity of Fungal Strains, and Individual and Non-Individual Factors

  • Alexandra Mpakosi,
  • Rozeta Sokou,
  • Martha Theodoraki and
  • Christiana Kaliouli-Antonopoulou

19 July 2024

The human gastrointestinal ecosystem, or microbiome (comprising the total bacterial genome in an environment), plays a crucial role in influencing host physiology, immune function, metabolism, and the gut–brain axis. While bacteria, fungi, viru...

  • Essay
  • Open Access
173 Citations
1,433 Views
6 Pages

Vaccination: The Cornerstone of an Efficient Healthcare System

  • Vanessa Rémy,
  • York Zöllner and
  • Ulrike Heckmann

Vaccination has made an important contribution to the decreased incidence of numerous infectious diseases and associated mortality. In 2013, it was estimated that 103 million cases of childhood diseases in the United States had been prevented by the...

  • Article
  • Open Access
18 Citations
4,242 Views
11 Pages

14 April 2021

Intrauterine malnutrition has a long-term effect on human health. This study aimed to evaluate the associations between exposure to famine in early life and obesity in adulthood in Chinese adults. A total of 5033 participants (22,132 observations) of...

  • Article
  • Open Access
4 Citations
5,500 Views
12 Pages

Human Milk: Fast Determination of Docosahexaenoic Acid (DHA)

  • Mahyara Markievicz Mancio Kus-Yamashita,
  • Cristiane Bonaldi Cano,
  • Vânia Claudia Barros Monteiro and
  • Regina Maria Catarino

3 March 2023

Human milk provides all the nutrients required by babies during the first six months of their life. Human milk lipids represent the main source of energy, contributing almost 50% of the total energy content. Additionally, fatty acids ensure the corre...

  • Review
  • Open Access
19 Citations
10,476 Views
15 Pages

Cryptosporidium: Still Open Scenarios

  • Stefania Pane and
  • Lorenza Putignani

Cryptosporidiosis is increasingly identified as a leading cause of childhood diarrhea and malnutrition in both low-income and high-income countries. The strong impact on public health in epidemic scenarios makes it increasingly essential to identify...

  • Review
  • Open Access
2 Citations
3,444 Views
14 Pages

De Cero a Siempre: Reflections on the Colombian Early Childhood Policy from a Human Rights Perspective

  • Cristian Jovan Rojas Romero,
  • Marisol Moreno Angarita,
  • Yeison Guerrero and
  • Laura Sofia Prieto Cifuentes

25 February 2025

This article critically examines De Cero a Siempre (DCAS), a cross-sectoral policy established in Colombia in 2016 to provide coordinated and comprehensive early childhood development services. The policy aims to promote optimal conditions for childr...

  • Article
  • Open Access
8 Citations
4,214 Views
12 Pages

Human Milk for Vulnerable Infants: Breastfeeding and Milk Sharing Practice among Ghanaian Women

  • Cecilia Obeng,
  • Frederica Jackson,
  • Christiana Nsiah-Asamoah,
  • Salome Amissah-Essel,
  • Barnabas Obeng-Gyasi,
  • Cydne A. Perry and
  • Ines Gonzalez Casanova

Human milk has the best impact on childhood survival. In Ghana, it is estimated that 43% of women exclusively breastfeed for 0–5 months and only 42% of breastfeeding mothers continue through 20–23 months. Although the Ghanaian government...

  • Article
  • Open Access
2 Citations
3,655 Views
30 Pages

Investing in early childhood development is an effective way to enhance human capital accumulation. Caregivers’ mental health is one of the most important factors influencing children’s development. Previous studies have found that mental...

  • Conference Report
  • Open Access
3 Citations
6,855 Views
8 Pages

23 February 2017

To understand suffering is to understand what it means to be human. Suffering focuses our attention on our vulnerability, which we would rather ignore or deny. As health care professionals (HCP) we need to be able to listen, to attune and be empathic...

  • Review
  • Open Access
173 Citations
14,237 Views
27 Pages

Iron Metabolism in Obesity and Metabolic Syndrome

  • Álvaro González-Domínguez,
  • Francisco M. Visiedo-García,
  • Jesús Domínguez-Riscart,
  • Raúl González-Domínguez,
  • Rosa M. Mateos and
  • Alfonso María Lechuga-Sancho

Obesity is an excessive adipose tissue accumulation that may have detrimental effects on health. Particularly, childhood obesity has become one of the main public health problems in the 21st century, since its prevalence has widely increased in recen...

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