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18 pages, 1448 KiB  
Article
Capturing Community Living Experiences and Health of Korean Community Spinal Cord Injury Population: A Cross-Sectional Survey
by Boram Lee and Hyeong Jun Kim
Int. J. Environ. Res. Public Health 2025, 22(8), 1222; https://doi.org/10.3390/ijerph22081222 - 5 Aug 2025
Abstract
(1) Background: People living with spinal cord injury (SCI) face numerous challenges in their lives in terms of health conditions, everyday activity, and participation in society, which are not fully recognized. To address such issues, a community survey with 125 questions for people [...] Read more.
(1) Background: People living with spinal cord injury (SCI) face numerous challenges in their lives in terms of health conditions, everyday activity, and participation in society, which are not fully recognized. To address such issues, a community survey with 125 questions for people living with SCI was conducted and the response rates, population characteristics, health and functioning problems are reported. (2) Methods: The survey questionnaire comprised 125 questions on SCI characteristics, health conditions, activities, participation, and environmental and personal factors. The survey response rates were calculated, and demographics and health and functioning characteristics were analyzed. (3) Results: A total of 890 individuals responded to the survey. The median age of the participants was 48 years (interquartile range (IQR), 39–56), and 76% of the population were males. Paraplegia (60%) and complete injury (58%) were the most common injury type, and the cause was mostly traumatic (92%). More health problems and lower quality of life were more frequent with older age and in patients without paid work. (4) Conclusions: The Ko-InSCI study provides valuable information in terms of health needs and service gaps for people with SCI in the community. Full article
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22 pages, 985 KiB  
Article
Understanding the Implementation of CareCoach—A Blended eHealth Intervention for Carers of People Living with Dementia: A Qualitative Process Evaluation Using Normalisation Process Theory
by Thando Katangwe-Chigamba, Margaret Guy, Jan R. Oyebode, Fiona M. Poland, Carl May, Chris Fox, Helen Morse and Jane L. Cross
Behav. Sci. 2025, 15(8), 1058; https://doi.org/10.3390/bs15081058 - 5 Aug 2025
Abstract
CareCoach seeks to enhance self-efficacy in family caregivers of people living with dementia and has been feasibility tested in a multicentre randomised controlled trial. The intervention offers two face-to-face sessions with a trained coach and access to an online platform with nine modules. [...] Read more.
CareCoach seeks to enhance self-efficacy in family caregivers of people living with dementia and has been feasibility tested in a multicentre randomised controlled trial. The intervention offers two face-to-face sessions with a trained coach and access to an online platform with nine modules. This paper reports findings from an embedded qualitative process evaluation assessing implementation from the implementer’s (‘coach’s’) (n = 8) perspective using individual interviews and implementer group discussions. Qualitative data were transcribed verbatim, inductively coded and analysed using Normalisation Process Theory. Implementers demonstrated (1) ‘Coherence’ by seeking to understand how CareCoach compared to current practice, highlighting the importance of supporting coaches to differentiate and identify boundaries between their new ‘coach role’ and usual practice; (2) ‘Cognitive Participation’ by reviewing training and resources to understand their role own responsibilities and facilitate delivery of coaching sessions; group supervision and peer support were also emphasised; (3) ‘Collective Action’ through interactions with carers to deliver key behavioural aspects such as goal setting, problem solving, and providing feedback; and (4) ‘Reflexive Monitoring’ by appraising the intervention to gain useful insights that could facilitate refinement of CareCoach training and delivery. This study provides a theoretically informed understanding of the implementation of CareCoach for caregivers of people living with dementia and provides recommendations to enhance training for coaches, intervention delivery and carer engagement. Full article
(This article belongs to the Special Issue Psychosocial Care and Support in Dementia)
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11 pages, 379 KiB  
Article
Preoperative Suffering of Patients with Central Neuropathic Pain and Their Expectations Prior to Motor Cortex Stimulation: A Qualitative Study
by Erkan Kurt, Richard Witkam, Robert van Dongen, Kris Vissers, Yvonne Engels and Dylan Henssen
Healthcare 2025, 13(15), 1900; https://doi.org/10.3390/healthcare13151900 - 4 Aug 2025
Abstract
Objective: This study aimed to improve the understanding of the lives of patients with chronic neuropathic pain planned for invasive motor cortex stimulation (iMCS) and assess their expectations towards this intervention and its impact. Methods: Semi-structured face-to-face interviews were conducted until [...] Read more.
Objective: This study aimed to improve the understanding of the lives of patients with chronic neuropathic pain planned for invasive motor cortex stimulation (iMCS) and assess their expectations towards this intervention and its impact. Methods: Semi-structured face-to-face interviews were conducted until saturation of data was reached. Patients were recruited from one university medical center in the Netherlands. All interviews were audio-recorded, transcribed verbatim, and subjected to thematic analysis using iterative and inductive coding by two researchers independently. Results: Fifteen patients were included (11 females; mean age 63 ± 9.4 yrs). Analysis of the coded interviews revealed seven themes: (1) the consequences of living with chronic neuropathic pain; (2) loss of autonomy and performing usual activities; (3) balancing energy and mood; (4) intimacy; (5) feeling understood and accepted; (6) meaning of life; and (7) the expectations of iMCS treatment. Conclusions: This is the first qualitative study that describes the suffering of patients with chronic neuropathic pain, and their expectations prior to invasive brain stimulation. Significant themes in the lives of patients with chronic pain have been brought to light. The findings strengthen communication between physicians, caregivers, and patients. Practice Implications: The insights gathered from the interviews create a structured framework for comprehending the values and expectations of patients living with central pain and reveal the impact of symptoms due to the central pain. This knowledge improves the communication between physicians and caregivers on one side and the patient on the other side. Furthermore, the framework enhances the capacity for shared decision-making, particularly in managing expectations related to iMCS. Full article
(This article belongs to the Special Issue Pain Management Practice and Research)
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18 pages, 797 KiB  
Article
On Becoming a Senior Staff Nurse in Taiwan: A Narrative Study
by Yu-Jen Hsieh and Yu-Tzu Dai
Healthcare 2025, 13(15), 1896; https://doi.org/10.3390/healthcare13151896 - 4 Aug 2025
Viewed by 133
Abstract
Background/Objectives: Senior nurses in Taiwan shoulder layered responsibilities shaped by professional roles, gendered expectations, and family duty. Although Taiwan faces a persistent shortage of experienced clinical nurses, limited research has explored how long-serving nurses sustain identity and commitment across decades of caregiving. [...] Read more.
Background/Objectives: Senior nurses in Taiwan shoulder layered responsibilities shaped by professional roles, gendered expectations, and family duty. Although Taiwan faces a persistent shortage of experienced clinical nurses, limited research has explored how long-serving nurses sustain identity and commitment across decades of caregiving. This study examines how senior staff nurses understand their journeys of becoming—and remaining—nurses within a culturally and emotionally complex landscape. Methods: Interviews were conducted between May 2019 and September 2023 in locations chosen by participants, with most sessions face-to-face and others undertaken via video conferencing during COVID-19. This narrative inquiry involved in-depth, multi-session interviews with five female senior staff nurses born in the 1970s to early 1980s. Each participant reflected on her life and career, supported by co-constructed “nursing life lines.” Thematic narrative analysis was conducted using McCormack’s five-lens framework and Riessman’s model, with ethical rigor ensured through reflexive journaling and participant validation. Results: Three overarching themes emerged: (1) inner strength and endurance, highlighting silent resilience and the ethical weight of caregiving; (2) support and responsibility in relationships, revealing the influence of family, faith, and relational duty; and (3) role navigation and professional identity, showing how nurses revisit meaning, self-understanding, and tensions across time. Participants described emotionally powerful moments, identity re-connection, and cultural values that shaped their paths. Conclusions: These narratives offer a relational and culturally embedded understanding of what it means to sustain a career in nursing. Narrative inquiry created space for reflection, meaning-making, and voice in a system where such voices are often unheard. Identity was not static—it was lived, reshaped, and held in story. Full article
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15 pages, 490 KiB  
Article
The Labour Conditions and Health of Migrant Agricultural Workers in Spain: A Qualitative Study
by Vanesa Villa-Cordero, Amalia Sillero Sillero, María del Mar Pastor-Bravo, Iratxe Pérez-Urdiales, María del Mar Jiménez-Lasserrotte and Erica Briones-Vozmediano
Healthcare 2025, 13(15), 1877; https://doi.org/10.3390/healthcare13151877 - 31 Jul 2025
Viewed by 154
Abstract
Background/Objectives: Agricultural workers in Spain with a migratory background face challenging working and living conditions that significantly affect their health. This study aimed to explore how professionals in healthcare, social services, civil society organisations, and labour institutions perceive that the working conditions [...] Read more.
Background/Objectives: Agricultural workers in Spain with a migratory background face challenging working and living conditions that significantly affect their health. This study aimed to explore how professionals in healthcare, social services, civil society organisations, and labour institutions perceive that the working conditions affect the physical health of this population. Methods: A qualitative descriptive study was conducted through 92 semi-structured interviews with professionals from six provinces in Spain. Data were analysed using thematic analysis following Braun and Clarke’s six-phase framework. Rigour was ensured through triangulation, independent coding, and interdisciplinary consensus. Results: Two overarching themes were identified: (1) the health consequences of workplace demands and environmental hazards, and (2) navigating health services such as sick leave and disability permits. These findings highlight how the impact of precarious working conditions and limited access to healthcare affect the physical health of migrant agricultural workers. Conclusions: The professionals interviewed described and relate precarious working conditions with adverse health outcomes among migrant agricultural workers. Their insights reveal the need for systemic reforms to enforce labour rights, ensure access to health services, and address the structural factors that contribute to exclusion and vulnerability. Full article
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18 pages, 255 KiB  
Article
Making the Invisible Visible: Addressing the Sexuality Education Needs of Persons with Disabilities Who Identify as Queer in Kenya
by Amani Karisa, Mchungwani Rashid, Zakayo Wanjihia, Fridah Kiambati, Lydia Namatende-Sakwa, Emmy Kageha Igonya, Anthony Idowu Ajayi, Benta Abuya, Caroline W. Kabiru and Moses Ngware
Disabilities 2025, 5(3), 69; https://doi.org/10.3390/disabilities5030069 - 31 Jul 2025
Viewed by 153
Abstract
Persons with disabilities face barriers to accessing sexuality education. For those who identify as queer, these challenges are compounded by stigma, ableism, and heteronormativity, resulting in distinct and overlooked experiences. This study explored the sexuality education needs of persons with disabilities who identify [...] Read more.
Persons with disabilities face barriers to accessing sexuality education. For those who identify as queer, these challenges are compounded by stigma, ableism, and heteronormativity, resulting in distinct and overlooked experiences. This study explored the sexuality education needs of persons with disabilities who identify as queer in Kenya—a neglected demographic—using a phenomenological approach. Data were collected through a focus group discussion with six participants and analyzed thematically. Three themes emerged: invisibility and erasure; unprepared institutions and constrained support networks; and agency and everyday resistance. Educational institutions often overlook the intersectional needs of persons with disabilities who identify as queer, leaving them without adequate tools to navigate relationships, sexuality, and rights. Support systems are often unprepared or unwilling to address these needs. Societal attitudes that desexualize disability and marginalize queerness intersect to produce compounded exclusion. Despite these challenges, participants demonstrated agency by using digital spaces and informal networks to resist exclusion. This calls for policy reforms that move beyond tokenism to address the lived realities of multiply marginalized groups. Policy reform means not only a legal or governmental shift but also a broader cultural and institutional process that creates space for recognition, protection, and participation. Full article
15 pages, 606 KiB  
Article
Assessment of the Physical and Emotional Health-Related Quality of Life Among Congestive Heart Failure Patients with Preserved and Reduced Ejection Fraction at a Quaternary Care Teaching Hospital in Coastal Karnataka in India
by Rajesh Kamath, Vineetha Poojary, Nishanth Shekar, Kanhai Lalani, Tarushree Bari, Prajwal Salins, Gwendolen Rodrigues, Devesh Teotia and Sanjay Kini
Healthcare 2025, 13(15), 1874; https://doi.org/10.3390/healthcare13151874 - 31 Jul 2025
Viewed by 194
Abstract
Introduction: Congestive heart failure (CHF), a complex clinical syndrome characterized by the heart’s inability to pump blood effectively due to structural or functional impairments, is a growing public health concern, with profound implications for patients’ physical and emotional well-being. In India, the burden [...] Read more.
Introduction: Congestive heart failure (CHF), a complex clinical syndrome characterized by the heart’s inability to pump blood effectively due to structural or functional impairments, is a growing public health concern, with profound implications for patients’ physical and emotional well-being. In India, the burden of CHF is rising due to aging demographics and increasing prevalence of lifestyle-related risk factors. Among the subtypes of CHF, heart failure with preserved ejection fraction (HFpEF), i.e., heart failure with left ventricular ejection fraction of ≥50% with evidence of spontaneous or provokable increased left ventricular filling pressure, and heart failure with reduced ejection fraction (HFrEF), i.e., heart failure with left ventricular ejection fraction of 40% or less and is accompanied by progressive left ventricular dilatation and adverse cardiac remodeling, may present differing impacts on health-related quality of life (HRQoL), i.e., an individual’s or a group’s perceived physical and mental health over time, yet comparative data remains limited. This study assesses HRQoL among CHF patients using the Minnesota Living with Heart Failure Questionnaire (MLHFQ), one of the most widely used health-related quality of life questionnaires for patients with heart failure based on physical and emotional dimensions and identifies sociodemographic and clinical variables influencing these outcomes. Methods: A cross-sectional analytical study was conducted among 233 CHF patients receiving inpatient and outpatient care at the Department of Cardiology at a quaternary care teaching hospital in coastal Karnataka in India. Participants were enrolled using convenience sampling. HRQoL was evaluated through the MLHFQ, while sociodemographic and clinical characteristics were recorded via a structured proforma. Statistical analyses included descriptive measures, independent t-test, Spearman’s correlation and stepwise multivariable linear regression to identify associations and predictors. Results: The mean HRQoL score was 56.5 ± 6.05, reflecting a moderate to high symptom burden. Patients with HFpEF reported significantly worse HRQoL (mean score: 61.4 ± 3.94) than those with HFrEF (52.9 ± 4.64; p < 0.001, Cohen’s d = 1.95). A significant positive correlation was observed between HRQoL scores and age (r = 0.428; p < 0.001), indicating that older individuals experienced a higher burden of symptoms. HRQoL also varied significantly across NYHA functional classes (χ2 = 69.9, p < 0.001, ε2 = 0.301) and employment groups (χ2 = 17.0, p < 0.001), with further differences noted by education level, gender and marital status (p < 0.05). Multivariable linear regression identified age (B = 0.311, p < 0.001) and gender (B = –4.591, p < 0.001) as significant predictors of poorer HRQoL. Discussion: The findings indicate that patients with HFpEF experience significantly poorer HRQoL than those with HFrEF. Older adults and female patients reported greater symptom burden, underscoring the importance of demographic-sensitive care approaches. These results highlight the need for routine integration of HRQoL assessment into clinical practice and the development of comprehensive, personalized interventions addressing both physical and emotional health dimensions, especially for vulnerable subgroups. Conclusions: CHF patients, especially those with HFpEF, face reduced HRQoL. Key factors include age, gender, education, employment, marital status, and NYHA class, underscoring the need for patient-centered care. Full article
(This article belongs to the Special Issue Patient Experience and the Quality of Health Care)
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17 pages, 266 KiB  
Article
“More than Hunger”: Experiences of Food Insecurity Among South Asian International Graduate Students at a U.S. University
by Lisa Henry, Doug Henry and Eva Perez Zepeda
Nutrients 2025, 17(15), 2508; https://doi.org/10.3390/nu17152508 - 30 Jul 2025
Viewed by 264
Abstract
Background/Objectives: International students pursuing higher education in the United States face unique challenges that increase their risk of food insecurity, including limited financial resources, employment restrictions, and cultural barriers. While food insecurity among domestic students has been widely studied, limited research focuses on [...] Read more.
Background/Objectives: International students pursuing higher education in the United States face unique challenges that increase their risk of food insecurity, including limited financial resources, employment restrictions, and cultural barriers. While food insecurity among domestic students has been widely studied, limited research focuses on the lived experiences of international graduate students. This study explores the challenges, perceptions, and coping strategies related to food insecurity among international graduate students at a large public university in North Texas. Methods: This qualitative, ethnographic study involved 20 semi-structured interviews with international graduate students who were clients of the university’s food pantry. Participants were recruited using purposive convenience sampling. Interviews focused on students’ experiences with food access, financial constraints, campus resources, and cultural food preferences. Data were analyzed using thematic coding in MAXQDA. Two standardized food insecurity measures—the USDA and FAO scales—were also administered and analyzed using SPSS. Results: Findings revealed that 85% of participants experienced limited access to nutritious and culturally appropriate foods, with 70% reporting hunger due to financial constraints. Themes included lack of cooking skills, limited campus food options, difficulty accessing familiar groceries, and limited job opportunities. Students expressed that food insecurity significantly impacted their physical health, mental well-being, and social lives, though many continued to prioritize academics over personal nourishment. Conclusions: Food insecurity among international graduate students is multifaceted, shaped by financial, cultural, and institutional barriers. Addressing this issue requires culturally sensitive interventions, improved access to diverse food options, tailored student support services, and institutional efforts to better understand and meet the needs of international students. Full article
34 pages, 725 KiB  
Article
A Qualitative Exploration of the Lived Experiences and Perspectives of Equine-Assisted Services Practitioners in the UK and Ireland
by Rita Seery, Lisa Graham-Wisener and Deborah L. Wells
Animals 2025, 15(15), 2240; https://doi.org/10.3390/ani15152240 - 30 Jul 2025
Viewed by 873
Abstract
Equine-Assisted Services (EAS), which incorporate horses in a variety of ways in an effort to improve human wellbeing, have grown in popularity in recent years. Although much research has been conducted regarding the benefits that horses may provide for human health and wellbeing, [...] Read more.
Equine-Assisted Services (EAS), which incorporate horses in a variety of ways in an effort to improve human wellbeing, have grown in popularity in recent years. Although much research has been conducted regarding the benefits that horses may provide for human health and wellbeing, little attention has been paid to practitioners’ experiences and perspectives of the field, despite the fact they are uniquely positioned to advance our understanding of this area. This study aimed to explore practitioners’ lived experiences of EAS, focusing on the benefits they observed, possible underlying mechanisms for any health benefits witnessed, and challenges faced in the area. Fifteen EAS practitioners from the UK/Ireland took part in qualitative semi-structured interviews, analysed using reflexive thematic analysis. Five themes were identified, three of which related to the horse’s influence on building connections, relationships, and enriching the process, whilst the remainder explored challenges within the field of EAS. These themes were explored through the practitioners’ lens, where possible linking them to our current understanding of human–animal interactions and related fields in the literature. Findings showed that horses, through EAS, were considered invaluable for building relationships, relational skills, and motivation to engage in whichever service was being provided. However, EAS was also viewed as complex. Concerns regarding competencies to practice, training, and lack of governance were expressed. These areas need further exploration and progress if EAS is to grow in efficacy and attain professional status. Full article
(This article belongs to the Special Issue Animal-Assisted Interventions: Effects and Mechanisms of Action)
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39 pages, 14288 KiB  
Article
Design and Performance Study of a Magnetic Flux Leakage Pig for Subsea Pipeline Defect Detection
by Fei Qu, Shengtao Chen, Meiyu Zhang, Kang Zhang and Yongjun Gong
J. Mar. Sci. Eng. 2025, 13(8), 1462; https://doi.org/10.3390/jmse13081462 - 30 Jul 2025
Viewed by 282
Abstract
Subsea pipelines, operating in high-pressure and high-salinity conditions, face ongoing risks of leakage. Pipeline leaks can pollute the marine environment and, in severe cases, cause safety incidents, endangering human lives and property. Regular integrity inspections of subsea pipelines are critical to prevent corrosion-related [...] Read more.
Subsea pipelines, operating in high-pressure and high-salinity conditions, face ongoing risks of leakage. Pipeline leaks can pollute the marine environment and, in severe cases, cause safety incidents, endangering human lives and property. Regular integrity inspections of subsea pipelines are critical to prevent corrosion-related leaks. This study develops a magnetic flux leakage (MFL)-based pig for detecting corrosion in subsea pipelines. Using a three-dimensional finite element model, this study analyzes the effects of defect geometry, lift-off distance, and operating speed on MFL signals. It proposes a defect estimation method based on axial peak-to-valley values and radial peak spacing, with inversion accuracy validated against simulation results. This study establishes a theoretical and practical framework for subsea pipeline integrity management, providing an effective solution for corrosion monitoring. Full article
(This article belongs to the Special Issue Theoretical Research and Design of Subsea Pipelines)
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27 pages, 1055 KiB  
Article
Effects of COVID-19 on Catastrophic Health Expenditures and Inequality in Benin: A Microsimulation Approach
by Albert N. Honlonkou, Nassibou Bassongui and Corinne B. Daraté
Economies 2025, 13(8), 222; https://doi.org/10.3390/economies13080222 - 29 Jul 2025
Viewed by 247
Abstract
This study assesses the effects of the COVID-19 pandemic on catastrophic health expenditures and income inequality in Benin. A microsimulation was calibrated to estimate the impact of the pandemic under three different shock scenarios: low, moderate, and severe. The analysis relies on secondary [...] Read more.
This study assesses the effects of the COVID-19 pandemic on catastrophic health expenditures and income inequality in Benin. A microsimulation was calibrated to estimate the impact of the pandemic under three different shock scenarios: low, moderate, and severe. The analysis relies on secondary data from household living condition surveys. The results indicate that the COVID-19 crisis would lead to a significant average income loss of up to 20% and income inequality, while the number of households with catastrophic health expenditures would increase by 4%. More importantly, the findings reveal heterogeneous impacts across households, with urban residents, younger individuals, more educated households, and male-headed households experiencing the greatest income decline. These findings underscore the need for targeted health coverage and employment policies to better protect vulnerable populations in Benin in the face of future shocks. Full article
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50 pages, 8673 KiB  
Article
Challenges of Integrating Assistive Technologies and Robots with Embodied Intelligence in the Homes of Older People Living with Frailty
by Abdel-Karim Al-Tamimi, Lantana Hewitt, David Cameron, Maher Salem and Armaghan Moemeni
Appl. Sci. 2025, 15(15), 8415; https://doi.org/10.3390/app15158415 - 29 Jul 2025
Viewed by 235
Abstract
The rapid increase in the global population of older adults presents a significant challenge, but also a unique opportunity to leverage technological advancements for promoting independent living and well-being. This study introduces the CIREI framework, which is a comprehensive model designed to enhance [...] Read more.
The rapid increase in the global population of older adults presents a significant challenge, but also a unique opportunity to leverage technological advancements for promoting independent living and well-being. This study introduces the CIREI framework, which is a comprehensive model designed to enhance the integration of smart home and assistive technologies specifically for pre-frail older adults. Developed through a systematic literature review and innovative and comprehensive co-design activities, the CIREI framework captures the nuanced needs, preferences, and challenges faced by older adults, caregivers, and experts. Key findings from the co-design workshop highlight critical factors such as usability, privacy, and personalised learning preferences, which directly influence technology adoption. These insights informed the creation of an intelligent middleware prototype named WISE-WARE, which seamlessly integrates commercial off-the-shelf (COTS) devices to support health management and improve the quality of life for older adults. The CIREI framework’s adaptability ensures it can be extended and refined to meet the ever-changing needs of the ageing population, providing a robust foundation for future research and development in user-centred technology design. All workshop materials, including tools and methodologies, are made available to encourage the further exploration and adaptation of the CIREI framework, ensuring its relevance and effectiveness in the dynamic landscape of ageing and technology. This research contributes significantly to the discourse on ageing in place, digital inclusion, and the role of technology in empowering older adults to maintain independence. Full article
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14 pages, 866 KiB  
Article
Switching to Long-Acting Cabotegravir and Rilpivirine in Turkey: Perspectives from People Living with HIV in a Setting of Increasing HIV Incidence
by Rıdvan Dumlu, Yeliz Çiçek, Mahir Kapmaz, Okan Derin, Halis Akalın, Uğur Önal, Egemen Özdemir, Çiğdem Ataman Hatipoğlu, Günay Tuncer Ertem, Alper Şener, Leyla Akgül, Yeşim Çağlar, Derya Tuna Ecer, Mustafa Kemal Çelen, Nur Bahar Oğuz, Figen Yıldırım, Deniz Borcak, Sevtap Şenoğlu, Eyüp Arslan, Sinan Çetin, Meryem Balcı and Ali Mertadd Show full author list remove Hide full author list
Medicina 2025, 61(8), 1373; https://doi.org/10.3390/medicina61081373 - 29 Jul 2025
Viewed by 480
Abstract
Background and Objectives: Long-acting cabotegravir and rilpivirine (LA-CAB/RPV) offers an alternative to daily oral antiretroviral therapy (ART) for people living with HIV (PLWH). Although LA-CAB/RPV has been approved in Turkey, the country remains in the pre-rollout period, and national data on patient [...] Read more.
Background and Objectives: Long-acting cabotegravir and rilpivirine (LA-CAB/RPV) offers an alternative to daily oral antiretroviral therapy (ART) for people living with HIV (PLWH). Although LA-CAB/RPV has been approved in Turkey, the country remains in the pre-rollout period, and national data on patient perspectives are lacking. This is the first nationwide study from Turkey, a setting of increasing HIV incidence, assessing PLWH perspectives on switching to LA-CAB/RPV and the influence of motivational factors on treatment preferences. Materials and Methods: A prospective, multicenter, cross-sectional study was conducted across 11 HIV treatment centers representing all regions of Turkey. Virologically suppressed PLWH meeting current eligibility criteria for LA-CAB/RPV were included. Treatment preferences (switch to LA-CAB/RPV or remain on oral ART) and five anticipated motivational domains, namely perceived efficacy, safety, convenience, privacy, and cost, were systematically assessed through structured, face-to-face interviews. Results: Among 200 eligible participants, 86% (n = 172) preferred switching to LA-CAB/RPV. In all subgroups, LA-CAB/RPV was preferred over oral ART, except for those with no formal literacy. Prior awareness of LA-CAB/RPV was significantly associated with the switching preference (p < 0.001), with healthcare providers being the most common source of information, at 45.5% (n = 172) (p < 0.001). Residential proximity to the healthcare center (p = 0.018) and all motivational factors significantly influenced the preference (p < 0.05). Notably, when participants who initially chose to remain on oral ART were asked whether they would reconsider switching if injections were administered every six months, overall preference for long-acting therapy increased from 86% to 98%. Conclusions: High clinical eligibility and strong acceptability for LA-CAB/RPV were observed among Turkish PLWH. Our findings demonstrate that structured motivational factors significantly influence the treatment preference. Addressing these patient-centered factors and logistical barriers may support the successful integration of long-acting therapies into routine HIV care. Future longer-interval agents may improve patient-centered acceptability. Full article
(This article belongs to the Section Infectious Disease)
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33 pages, 11684 KiB  
Article
Face Spoofing Detection with Stacking Ensembles in Work Time Registration System
by Rafał Klinowski and Mirosław Kordos
Appl. Sci. 2025, 15(15), 8402; https://doi.org/10.3390/app15158402 - 29 Jul 2025
Viewed by 125
Abstract
This paper introduces a passive face-authenticity detection system, designed for integration into an employee work time registration platform. The system is implemented as a stacking ensemble of multiple models. Each model independently assesses whether a camera is capturing a live human face or [...] Read more.
This paper introduces a passive face-authenticity detection system, designed for integration into an employee work time registration platform. The system is implemented as a stacking ensemble of multiple models. Each model independently assesses whether a camera is capturing a live human face or a spoofed representation, such as a photo or video. The ensemble comprises a convolutional neural network (CNN), a smartphone bezel-detection algorithm to identify faces displayed on electronic devices, a face context analysis module, and additional CNNs for image processing. The outputs of these models are aggregated by a neural network that delivers the final classification decision. We examined various combinations of models within the ensemble and compared the performance of our approach against existing methods through experimental evaluation. Full article
(This article belongs to the Special Issue Application of Artificial Intelligence in Image Processing)
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12 pages, 1307 KiB  
Article
Protection Against Transplacental Transmission of a Highly Virulent Classical Swine Fever Virus Two Weeks After Single-Dose FlagT4G Vaccination in Pregnant Sows
by Liani Coronado, Àlex Cobos, Adriana Muñoz-Aguilera, Sara Puente-Marin, Gemma Guevara, Cristina Riquelme, Saray Heredia, Manuel V. Borca and Llilianne Ganges
Vaccines 2025, 13(8), 803; https://doi.org/10.3390/vaccines13080803 - 28 Jul 2025
Viewed by 380
Abstract
Background/Objectives: Classical swine fever (CSF) continues to challenge global eradication efforts, particularly in endemic regions, where pregnant sows face heightened risks of vertical transmission following exposure to CSFV. Methods: This study evaluates the early protective efficacy of FlagT4G, a novel live attenuated DIVA-compatible [...] Read more.
Background/Objectives: Classical swine fever (CSF) continues to challenge global eradication efforts, particularly in endemic regions, where pregnant sows face heightened risks of vertical transmission following exposure to CSFV. Methods: This study evaluates the early protective efficacy of FlagT4G, a novel live attenuated DIVA-compatible vaccine. Pregnant sows were vaccinated at mid-gestation and challenged 14 days later with a highly virulent CSFV strain. Results: FlagT4G conferred complete clinical protection, preventing both maternal viremia and transplacental transmission. No CSFV RNA, specific antibodies, or IFN-α were detected in fetal samples from vaccinated animals. In contrast, unvaccinated sows exhibited clinical signs, high viral loads, and widespread fetal infection. Interestingly, early protection was observed even in the absence of strong humoral responses in some vaccinated sows, suggesting a potential role for innate or T-cell-mediated immunity in conferring rapid protection. Conclusions: The demonstrated efficacy of FlagT4G within two weeks of vaccination underscores its feasibility for integration into emergency vaccination programs. Its DIVA compatibility and ability to induce early fetal protection against highly virulent CSFV strains position it as a promising tool for CSF control and eradication strategies. Full article
(This article belongs to the Special Issue Vaccines for Porcine Viruses)
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