Search Results (152)

Dense aggregations of species in the family Pinnidae give soft substrata a specific characterization. They may influence the biological and physical properties of the surrounding sediments. Bottom-trawl samplings performed in the Sea of Marmara revealed populations of a large pinnid species, particularly at depths of 40–45 m in soft substrata. Both morphological and DNA analyses confirmed the species’ taxonomic identity as Atrina fragilis. This species had a population density ranging from 31 to 469 ind.km⁻², and the shell lengths ranged from 21.3 to 31 cm. A total of 47 macrozoobenthic species belonging to eight taxonomic groups were found on the shells of ten live and nine dead A. fragilis individuals. Polychaeta accounted for 53% of the total number of species and 75% of the total number of individuals. Among these species, Protula tubularia and Serpula concharum comprised almost 30% of all epifaunal populations. Community parameters changed according to the shell length and width. Different faunal assemblages were encountered on the shells. Given the ecological significance of A. fragilis as both a habitat-forming and sensitive benthic species, conservation measures should prioritize the protection of known habitats and the regulation of activities that lead to seabed disturbance. Full article

Temperature control in a continuous stirred tank reactor (CSTR) poses significant challenges due to the process’s inherent nonlinearities and uncertain parameters. This study proposes an innovative solution by developing an adaptive nonlinear proportional–integral–derivative (NPID) controller. The nonlinear gain that dynamically scales the error fed to the integrator is enhanced for optimized performance. The network’s ability to approximate nonlinear functions and its online learning capabilities are leveraged by effectively integrating an NPID control scheme with a radial basis function neural network (RBFNN). This synergistic approach provides a more robust and reliable control strategy for CSTRs. To assess the proposed method’s feasibility, a set of simulations was conducted for tracking, disturbance rejection, and parameter variations. These results were compared with those of an adaptive RBFNN-based PID (APID) controller under identical conditions. The simulations indicated that the proposed method achieved reductions in maximum overshoot of 33.7% and settling time of 54.2% for upward and downward setpoint changes and 27.2% and 5.3% for downward and upward setpoint changes compared to the APID controller. For disturbance changes, the proposed method reduced the peak magnitude (M_peak) by 4.9%, recovery time (t_rcy) by 23.6%, and integral absolute error by 16.2%. Similarly, for parameter changes, the reductions were 3.0% (M_peak), 26.4% (t_rcy), and 24.4% (IAE). Full article

Aims. In the present study, we investigated the associations between the three identity dimensions of Kaufman (Consolidated Identity, Disturbed Identity, Lack of Identity) and symptoms of personality disorders (PDs) in 176 female inpatients with an eating disorder (ED). We examined five aspects: the prevalence of categorical PD diagnoses in patients with EDs; the relationship between dimensional PD scores and identity dimensions as well as their relationships with age and ED subtype; and the unique variance in dimensional PD scores explained by identity dimensions, while controlling for age and ED subtype. Methods. To assess identity functioning, we made use of the Self-Concept and Identity Measure, and to assess PDs, we used the categorical and dimensional scores of the Assessment of DSM-IV Personality Disorders. Results. The findings showed that the avoidant, obsessive–compulsive, and borderline categorical PDs were the most frequently reported PDs. Age was negatively related to all Cluster B PDs and Disturbed Identity, and binge-eating/purging ED patients reported significantly more Cluster B PD features compared to restrictive ED patients. ED subtype and identity dimensions were unrelated. Correlational analysis showed that all dimensional PD scores were positively related to Disturbed Identity and Lack of Identity and negatively related to Consolidated Identity. The results of the hierarchical regression analyses showed that Cluster A PDs were significantly predicted by Lack of Identity, controlled for age and ED subtype. Additionally, Cluster B PDs were significantly predicted by Disturbed Identity. Finally, two of the three cluster C PDs were predicted by Lack of Identity (avoidant and obsessive–compulsive PD), whereas the dependent PD was explained by Disturbed Identity. Conclusions. The co-occurrence of identity issues in both PDs and EDs underscores the role of identity as a transdiagnostic feature. Accordingly, using identity-based interventions in treatment may have broad therapeutic benefits across these disorders. Full article

Hyperekplexia (OMIM 149400), a sensorimotor syndrome of perinatal clinical relevance, causes newborns to display an energic startle reflex in response to certain trivial stimuli. This condition can be lethal due to apnea episodes. The disease is caused by a blockade of glycinergic neurotransmission. Glycinergic interneurons preserve their identity by the activity of the surface glycine transporter GlyT2, which supplies glycine to presynaptic terminals to maintain glycine content in synaptic vesicles. Loss-of-function mutations in the GlyT2 gene (SLC6A5) cause a presynaptic form of human hyperekplexia. Here, we describe a new GlyT2 variant found in an infantile patient diagnosed with hyperekplexia. A missense mutation in the open reading frame of the GlyT2 gene inherited in homozygosity caused the substitution G449E in a residue highly conserved across the phylogenetic scale. The sequences of the glycine receptor genes GLRA1 and GLRB did not show abnormalities. We expressed the recombinant GlyT2 variant in heterologous cells and analyzed its pathogenic mechanism. The transporter was totally inactive, behaving as a bona fide loss-of-function mutant. Furthermore, the mutation promoted the abnormal insertion of the protein into the membrane, leading to its large incorporation into lipid rafts. However, there was no apparent alteration of wild-type trafficking upon mutant coexpression, as the mutant was prematurely degraded from the endoplasmic reticulum. Rescue with chemical chaperones was not possible for this mutant. Proteomics demonstrated that the expression of the mutant induced the unfolded protein response and interfered with raft-dependent processes. Therefore, the new variant causes a loss of function regarding GlyT2 activity but a gain of function as a cell proteostasis disturber. Full article

This paper presents a novel wireless control framework for electric drive systems by employing a fuzzy brain emotional learning neural network (FBELNN) controller in conjunction with a Disturbance Observer (DO). The communication scheme uses chaotic system dynamics to ensure data confidentiality and robustness against disturbance in wireless environments. To be applied to embedded microprocessors, the continuous-time chaotic system is discretized using the Grunwald–Letnikov approximation. To avoid the loss of generality of chaotic behavior, Lyapunov exponents are computed to validate the preservation of chaos in the discrete-time domain. The FBELNN controller is then developed to synchronize two non-identical chaotic systems under different initial conditions, enabling secure data encryption and decryption. Additionally, the DOB is introduced to estimate and mitigate the effects of bounded uncertainties and external disturbances, enhancing the system’s resilience to stealthy attacks. The proposed control structure is experimentally implemented on a wireless communication system utilizing ESP32 microcontrollers (Espressif Systems, Shanghai, China) based on the ESP-NOW protocol. Both control and feedback signals of the electric drive system are encrypted using chaotic states, and real-time decryption at the receiver confirms system integrity. Experimental results verify the effectiveness of the proposed method in achieving robust synchronization, accurate signal recovery, and a reliable wireless control system. The combination of FBELNN and DOB demonstrates significant potential for real-time, low-cost, and secure applications in smart electric drive systems and industrial automation. Full article

Background: Borderline personality disorder (BPD) is a severe psychiatric condition characterised by emotional instability, impulsivity, interpersonal dysfunction, and self-injurious behaviours. Despite growing clinical interest, the neuropsychological mechanisms underlying these symptoms are still not fully understood. This review aims to summarise findings from neuroimaging, psychophysiological, and neurodevelopmental studies in order to clarify the neurobiological and physiological basis of BPD, with a particular focus on emotional dysregulation and implications for the treatment of adolescents. Methods: A narrative review was conducted, integrating results from longitudinal neurodevelopmental studies, functional and structural neuroimaging research (e.g. FMRI and PET), and psychophysiological assessments (e.g., heart rate variability and cortisol reactivity). Studies were selected based on their contribution to understanding the neural correlates of BPD symptom dimensions, particularly emotion dysregulation, impulsivity, interpersonal dysfunction, and self-harm. Results: Findings suggest that early reductions in amygdala volume, as early as age 13 predict later BPD symptoms. Hyperactivity of the amygdala, combined with hypoactivity in the prefrontal cortex, underlies deficits in emotion regulation. Orbitofrontal abnormalities correlate with impulsivity, while disruptions in the default mode network and oxytocin signaling are related to interpersonal dysfunction. Self-injurious behaviour appears to serve a neuropsychological function in regulating emotional pain and trauma-related arousal. This is linked to disruption of the hypothalamic-pituitary-adrenal (HPA) axis and structural brain alterations. The Unified Protocol for Adolescents (UP-A) was more effective to Mentalization-Based Therapy for Adolescents (MBT-A) at reducing emotional dysregulation compared, though challenges in treating identity disturbance and relational difficulties remain. Discussion: The reviewed evidence suggests that BPD has its in early neurodevelopmental vulnerability and is sustained by maladaptive neurophysiological processes. Emotional dysregulation emerges as a central transdiagnostic mechanism. Self-harm may serve as a strategy for regulating emotions in response to trauma-related neural dysregulation. These findings advocate for the integration of neuroscience into psychotherapeutic practice, including the application of neuromodulation techniques and psychophysiological monitoring. Conclusions: A comprehensive understanding of BPD requires a neuropsychologically informed framework. Personalised treatment approaches combining pharmacotherapy, brain-based interventions, and developmentally adapted psychotherapies—particularly DBT, psychodynamic therapy, and trauma-informed care—are essential. Future research should prioritise interdisciplinary, longitudinal studies to further bridge the gap between neurobiological findings and clinical innovation. Full article

Silty clay is extensively distributed in northern China. Numerous seismic events have demonstrated that underground structures embedded in silty clay strata are prone to severe damage during earthquakes. This study employs dynamic cyclic triaxial tests on undisturbed and remolded specimens (50–300 kPa confining pressures) to pioneer the quantification of pressure-amplified structural superiority. The experimental results reveal that: (1) Undisturbed soils exhibit 20–30% higher maximum shear stress (τ_dmax) and shear modulus (G_dmax) than remolded counterparts at 300 kPa, far exceeding the <5% deviation at 50 kPa due to enhanced particle-cementation synergy under pressure. (2) The normalized shear modulus ratio (G_d/G_dmax) exhibits low sensitivity to confining pressure, with G_d/G_dmax–γ_d relationship curves predominantly confined within a narrow band range. A triphasic evolutionary characteristic is manifested in the progressive reduction of G_d/G_dmax with increasing shear strain (γ_d), and quasi-linear attenuation is observed within the shear strain range of 1 × 10⁻⁴ ≤ γ_d ≤ 1 × 10⁻². (3) Remolded and undisturbed specimens demonstrate close correspondence in damping ratio (λ_d) across consolidation pressures. Under identical γ_d conditions, undisturbed specimens consistently exhibit lower λ_d values than remolded counterparts, attributable to enhanced energy dissipation resulting from structural homogenization in remolded soils, with λ_dmax magnitudes ranging between 0.2 and 0.3. The research provides mechanistic insights for seismic design of underground structures in silty clay terrains, particularly regarding disturbance sensitivity under deep burial conditions. Full article

Striking belief distortions may accompany various disorders of awareness that are predominantly associated with right hemispheric cerebral dysfunction. Distortions may range on a continuum of pathological severity, from the unawareness of paralysis in anosognosia for hemiplegia, to a more startling disturbance in denial of paralysis where belief may starkly conflict with reality. The patients’ beliefs about their limitations typically represent attempts to make sense of limitations or to impart meaning to incongruous facts. These beliefs are often couched in recollections from past memories or previous experience, and are hard to modify even given new information. Various explanations of unawareness have been suggested, including sensory, cognitive, monitoring and feedback operations, feedforward mechanisms, disconnection theories, and hemispheric asymmetry hypotheses, along with psychological denial, to account for the curious lack of awareness in anosognosia and other awareness disorders. This paper addresses these varying explanations of the puzzling beliefs regarding hemiparesis in anosognosia. Furthermore, using the multi-dimensional nature of unawareness in anosognosia as a model, some startling belief distortions in other right-hemisphere associated clinical syndromes are also explored. Other neurobehavioral disturbances, though perhaps less common, reflect marked psychopathological distortions. Startling disorders of belief are notable in somatic illusions, non-recognition or delusional misattribution of limb ownership (asomatognosia, somatoparaphrenia), or delusional identity (Capgras syndrome) and misidentification phenomena. Difficulty in updating beliefs as a source of unawareness in anosognosia and other awareness disorders has been proposed. Processes of belief development are considered to be patterns of thought, memories, and experience, which coalesce in a sense of the bodily and personal self. A common consequence of such disorders seems to be an altered representation of the self, self-parts, or the external world. Astonishing nonveridical beliefs about the body, about space, or about the self, continue to invite exploration and to stimulate fascination. Full article

Ethnobotanical knowledge and biodiversity are critical components of sustainable natural resource management, especially in regions undergoing rapid environmental and socio-economic change. In Northeast Thailand, traditional plant knowledge is deeply intertwined with local cultural identity but faces increasing threats from urbanization, agricultural expansion, and generational shifts. This study presents a floristic and ethnobotanical survey of the Khanthararat Public Benefit Forest, a community-managed remnant forest in Maha Sarakham Province, documenting 110 plant species from 42 families. The Fabaceae family was the most diverse, consistent with other tropical ecosystems. Predominantly native species (85.45%) indicate minimal disturbance, while introduced (11.82%) and endemic species (2.73%) reflect ecological complexity. Ethnobotanical data revealed 34 wild edible species, 33 medicinal plants, and 19 ornamental species used by the local community, highlighting the forest’s vital role in supporting livelihoods and cultural practices. High Use Values (UVs) for species such as Spondias pinnata and Coccinia grandis underline their dual importance in food and medicine. Informant Consensus Factor (Fic) values demonstrate strong agreement on plant use for reproductive and musculoskeletal health, reflecting well-established traditional knowledge. The findings underscore the forest’s dual significance as an ecological hotspot and a repository of cultural heritage, providing essential ecosystem services including biodiversity conservation, climate regulation, and cultural provisioning. By integrating traditional knowledge with biodiversity assessment, this study offers valuable insights for community-based conservation strategies that sustain both ecological integrity and cultural resilience in Northeast Thailand. Full article

This paper presents a three-degrees-of-freedom origami parallel robot that is free from parasitic motion. This robot is designed to achieve one translational and two rotational motions within its workspace, enabling precise orientation about a fixed point—a capability unattainable for parallel robots with parasitic motion. The elimination of parasitic motion is critical, allowing the use of this device in applications requiring high precision. The robot’s key kinematic features include a parasitic motion-free workspace, large orientational capability, compactness, decoupled motion, simplicity in manufacturing and control, mechanically pivoted rotation of the moving platform, and scalability. These characteristics make the robot particularly well-suited for micromanipulation tasks in both manufacturing and medical applications. In manufacturing, it can enable high-precision operations such as micro-assembly, optical fiber alignment, and semiconductor packaging. In medicine, it can support delicate procedures such as microsurgery and cell injection, where sub-micron accuracy, high stability, and precise motion decoupling are critical requirements. The use of nearly identical limbs simplifies the architecture, facilitating easier design, manufacture, and control. The kinematics of the robot is analyzed using reciprocal screw theory for an analytic constraint-embedded Jacobian. To further enhance operational accuracy and robustness, particularly in the presence of uncertainties or disturbances, a deep neural network (DNN)-based state estimation method is integrated, providing accurate forward kinematic predictions. The construction of the robot utilizes origami-inspired limbs and joints, enhancing miniaturization, manufacturing simplicity, and foldability. Although capable of being scaled up or further miniaturized, its current size is 66 mm × 68 mm × 100 mm. The robot’s moving platform is theoretically and experimentally proven to be free of parasitic motion and possesses a large orientation capability. Its unique features are demonstrated, and its potential for high-precision applications is thoroughly discussed. Full article

Industrial dispensing systems consist of many components, and the temperature characteristics of these components vary significantly. To address this, a segmented adaptive PID temperature control method is proposed in this paper. This method integrates a segmented temperature control algorithm with a variable control coefficient algorithm based on output power, which not only ensures minimal overshoot in the system but also enhances its disturbance rejection capability. Experimental results demonstrate that, under identical conditions, compared with the traditional PID method, the proposed method reduces overshoot by 2–4 °C and decreases the amplitude of temperature fluctuations after disturbance by approximately 0.2 °C. Full article

Background: Beach volleyball (BVb) is a highly demanding Olympic sport characterized by intense physical activity and unique environmental challenges, including varying weather conditions and sandy, unstable court surfaces. Despite its popularity, there is a notable lack of scientific research addressing the metabolic and immune responses of elite female athletes in this sport. This study aims to address this gap by investigating two world-class Olympic medalists, female BVb players, who represent a country with a rich history in the sport. Methods: Two athletes underwent a simulated competition day consisting of two matches. A standardized protocol was utilized to collect blood and urine samples at seven time points, allowing for analysis throughout the competition and recovery phases. The analysis included various electrolytes, as well as hematological, metabolic, and inflammatory markers. Additionally, we assessed selected hormones, such as insulin, serotonin, ACTH, and cortisol, along with amino acids related to energy metabolism and neurotransmitter synthesis. Results: Both athletes presented a trend toward electrolyte disturbances, especially hypokalemia, with a mean decrease of 15% and individual values reaching as low as 3.3 mmol/L post-match. This indicates that BVb may pose a risk for such disturbances. Additionally, the matches led to 20% to 60% increases in muscle injury markers, with incomplete recovery even after a day of rest, signaling persistent physiological stress post-competition. This increase was matched by stimulating stress hormones (ACTH and cortisol rose up to 4-fold and 3-fold, respectively), and markers of exercise intensity, such as lactate and ammonium. Moreover, the simulated BVb competition day impacted the amino acid response, with the Fischer ratio (BCAA/AAA) and blood tryptophan decreasing to a minimum of 60% of the initial levels and blood serotonin increasing by up to 180%, which are signs of an increased risk of central fatigue onset, according to the Fischer and Newsholme theory. Conclusions: The responses examined in this exploratory study contribute to a deeper understanding of the metabolic and immune demands placed on elite female BVb players, suggesting practical applications. By addressing the similar physiological responses observed among the athletes and emphasizing their unique individual responses—despite following the same protocol under identical conditions and sharing similar life habits for an extended period—this study highlights the critical necessity for the n-of-1 monitoring of athletes. Full article

The feminist perspective is relevant to the understanding, prevention, and treatment of disturbances in eating and body image. However, limited empirical research has explored the relationship between feminist identity and weight stigma. The present study examined the associations between feminist beliefs, externalized weight bias, internalized weight bias, body image, and eating disturbances. Two hundred sixty-five racially and ethnically diverse young women were recruited from a university in the Pacific Rim. Participants completed questionnaires online and interrelationships were examined using a series of regressions. Externalized weight bias was significantly negatively associated with both feminist beliefs and identification as a feminist. However, stronger feminist beliefs and identity were significantly associated with higher internalized weight bias, worse body dissatisfaction, and greater incidence of eating disturbances. The results of the present study suggest that structural change driven by feminist values and principles may be effective for reducing weight bias and possibly other risk factors present in broader society but potentially less effective on an individual level. Longitudinal research is needed to confirm the direction of these relationships and to understand which components of feminist theory and feminist values can be most helpful in reducing weight bias on an individual level, while still addressing structural change. Full article

In this study, we analysed remote sensing data collected during the Beirut port explosion on 4 August 2020 at 15.08 UT. For this purpose, we selected three Low-Earth-Orbit (LEO) satellite missions that passed near the Beirut port explosion site immediately after the event. The satellites involved were Swarm-B, the Defence Meteorological Satellite Program (DMSP-F17), and the Constellation Observing System for Meteorology, Ionosphere, and Climate (COSMIC-2). This study focused on identifying the possible ionospheric signatures of explosion in both hemispheres. The conjugate hemispheric points were traced using the International Geomagnetic Reference Field (IGRF) model. We found that the satellite data revealed disturbances not only over the explosion site in the Northern Hemisphere, but also in its corresponding conjugate region in the Southern Hemisphere. Ionospheric electron density disturbances were observed poleward in the conjugate hemispheres along the paths of the Swarm and DMSP satellites, whereas the magnetic field data from Swarm-B showed both equatorward and poleward disturbances. Additionally, the ionospheric disturbances detected by Swarm-B (18:52 UT) and DMSP-F17 (16:30 UT) at the same location suggested travelling ionospheric disturbance (TID) oscillations with identical spatial patterns for both satellites, whereas the disturbances observed by COSMIC-2 south of the explosion site (10°N) indicated the radial propagation of TIDs. COSMIC-2 not only recorded equatorward topside (>550 km) ionospheric electron density disturbances, but also in the conjugate hemispheres, which aligns with the time frame reported in previous studies. These ionospheric features observed by multiple LEO satellites indicate that the detected signatures originated from the event, highlighting the importance of integrating space missions for monitoring and gaining deeper insight into space hazards. The absence of equatorward ionospheric disturbances at the altitudes of DMSP-F17 and Swarm-B warrant further investigation. Full article

Background: Excessive daytime sleepiness (EDS) and fatigue are two impactful symptoms, frequently associated with sleep disorders, which can worsen the quality of life. Due to overlapping features and patient-report ambiguity a clear-cut distinction between EDS and fatigue can become a challenging issue. We aimed to investigate the prevalence and consequences of these two conditions in several sleep pathologies, examining their social, psychological, and dietary impact, with a focus on gender-related differences and occupational status. Methods: We prospectively recruited for an online survey 136 adult outpatients (60 females) affected by various sleep disorders and admitted to our Sleep Disorders Center in Parma, Italy. Patients were asked to complete the following tests: Epworth Sleepiness Scale, Fatigue Severity Scale, Pittsburgh Sleep Quality Index, Difficulties in Emotion Regulation Scale, Depression Anxiety Stress Scale-21, Hyperarousal Scale, the Addiction-like Eating Behaviors Scale, Work Productivity and Activity Impairment Questionnaire, MEDI-Lite, and EQ-5D Health Questionnaire. Results:Fatigue was the primary daily symptom leading to serious repercussions on social/emotional and psychological well-being, while daytime sleepiness showed a less relevant role. Women reported higher levels of fatigue, sleep disturbances, emotional dysregulation, hyperarousal, and work productivity impairments. Unemployed people experienced a higher degree of fatigue, with multi-level negative consequences. Conclusions: We suggest sleep clinicians place a greater emphasis on the assessment of fatigue during clinical interviews, keeping in mind the greater vulnerability of females, experiencing disproportionate consequences. Further studies should expand our findings, exploring a wider range of gender identities and recruiting larger samples of patients. Full article