Search Results (29)

Background: Acute kidney injury (AKI) in critically ill patients is often complicated by arrhythmias, potentially affecting outcomes. This study aimed to develop predictive models for arrhythmias in AKI patients and assess the impact of antiarrhythmic drugs on in-hospital mortality. Methods: We conducted a multi-database retrospective cohort study using MIMIC-IV and eICU databases. XGBoost and Bayesian Information Criterion (BIC) models were employed to identify key predictors of arrhythmias. Weighted log-rank and Cox analysis evaluated the effect of amiodarone and metoprolol on in-hospital mortality. Results: Among 14,035 critically ill AKI patients, 5614 individuals (40%) developed arrhythmias. Both XGBoost and BIC showed predictive power for arrhythmias. The XGBoost model identified HR_max, HR_min, and heart failure as the most important features, while the BIC model highlighted heart failure had the highest odds ratio (OR 1.18, 95% CI 1.16–1.20) as a significant predictor. Patients experiencing arrhythmia is associated with in-hospital mortality (arrhythmia group: 636 (11.3%) vs. non-arrhythmia group: 587 (7.0%), p < 0.01). Antiarrhythmic medications showed a statistically significant effect on in-hospital mortality (amiodarone: HR 0.28, 95% CI 0.19–0.41, p < 0.01). Conclusions: Our predictive models demonstrated a robust discriminatory ability for identifying arrhythmia occurrence in critically ill AKI patients, with identified risk factors showing strong clinical relevance. The significant association between arrhythmia occurrence and increased in-hospital mortality underscores the clinical importance of early identification and management. Furthermore, amiodarone therapy effectively reduced the risk of in-hospital mortality in these patients, even after accounting for time-dependent biases. The findings highlight the necessity of precise arrhythmia definition, careful consideration of time-dependent covariates, and comprehensive model validation for clinically actionable insights. Full article

This paper provides guidance for organizations and individuals to combat the subtle yet impactful discrimination of microaggressions. Drawing from interdisciplinary sources, it integrates insights from organizational science and health psychology, with a focus on diversity, equity, and inclusion (DEI). Through a review of 69 sources, including empirical studies, government reports, and policy analyses, the paper identifies where microaggressions are likely to occur, why they matter to managers, and how they can be addressed in the workplace. Practical, evidence-based strategies are offered to help reshape perceptions, reduce discriminatory behaviors, and create more equitable opportunities, ultimately fostering greater satisfaction and enabling diverse workplaces to reach their full potential. The findings emphasize the importance of mindful management and actionable DEI practices that drive meaningful change in workplace culture. By providing tools to recognize and respond to microaggressions, this paper contributes to broader efforts to reduce inequities and enhance the work environment, ensuring employees can thrive, regardless of their subgroup identities. Full article

Introduction: Cytokine release syndrome (CRS) and immune cell-associated neurotoxicity syndrome (ICANS) are both serious complications of CAR-T therapy associated with endothelial dysfunction, prompting prior use of a modified version of the endothelial activation and stress index (m-EASIX) to predict the occurrence of severe ICANS and CRS. Previous studies have linked both hypophosphatemia and elevated IL6 levels to CRS and ICANS. Our study aimed to enhance the early prediction of both syndromes by integrating phosphorous and IL-6 both together and separately into the m-EASIX score. Methods: Forty-two patients with non-Hodgkin’s lymphoma presenting for CAR-T treatment were used to generate three variations in the m-EASIX score, assessing performance for the clinically actionable time points of day +0 through day +3. Results: The addition of phosphorous through the P-m-EASIX improved the predictive capabilities for the occurrence of ICANS, most notably on day +1 (AUC 89.6%; p = 0.0090, OR of 2.23; p = 0.0096) compared to the m-EASIX (AUC 80.8%; p = 0.0047, OR 1.72; p = 0.0046). The P-m-EASIX also showed enhanced predictive capabilities for the occurrence of CRS, with peak discriminatory function on day +3 (AUC 92.0%; p = <0.0001, OR 2.21; p = 0.0014). The addition of IL6 in the IL6-m-EASIX showed the highest discriminatory capacity for the prediction of CRS progression to grade ≥ 2 with peak function on day +3 (AUC 89.7%; p = 0.0040, OR 1.57; p = 0.031). Conclusions: Incorporating phosphorus levels into the m-EASIX score offered a cost-effective and straightforward method to improve the prediction of CAR-T toxicities. Larger-scale studies assessing the effectiveness of including phosphorus and IL-6 in the m-EASIX score to mitigate complications associated with CAR-T therapy are warranted. Full article

A form of discrimination associated with international migration is workplace discrimination. This study focused on identifying discriminatory actions in working conditions, as perceived by Venezuelan immigrants residing in Cúcuta, La Parada and Los Patios (Colombia). The goal was to determine the measures employers could implement to reduce such discriminatory actions. A quantitative, non-probabilistic snowball sampling method was adopted, followed by a survey of 177 immigrants. An exploratory and descriptive analysis of the variables under study was conducted using multivariate analysis techniques of multiple correspondences with optimal scaling. The study also explored discrimination perceived by employed and unemployed immigrants, as well as by those who had been denied work during their job search. The study concluded that to address discrimination by employers, culture should be linked to ethics and corporate social responsibility, enabling organisations to successfully raise awareness among their staff, managers and those in charge of human resource management about non-discrimination policies, equal treatment and opportunities, from design to implementation, along with necessary monitoring by Labour Inspecting Offices. Full article

Crop damage attributed to pest birds is an important problem, particularly in low-income countries. This paper describes a prototype system for pest bird detection using a Conv1D neural network model followed by scaring actions to reduce the presence of pest birds on farms. Acoustic recorders were deployed on farms for data collection, supplemented by acoustic libraries. The sounds of pest bird species were identified and labeled. The labeled data were used in Edge Impulse to train a tinyML Conv1D model to detect birds of interest. The model was deployed on Arduino Nano 33 BLE Sense (nodes) and XIAO (Base station) microcontrollers to detect the pest birds, and based on the detection, scaring sounds were played to deter the birds. The model achieved an accuracy of 96.1% during training and 92.99% during testing. The testing F1 score was 0.94, and the ROC score was 0.99, signifying a good discriminatory ability of the model. The prototype was able to make inferences in 53 ms using only 14.8 k of peak RAM and only 43.8 K of flash memory to store the model. Results from the prototype deployment in the field demonstrated successful detection and triggering actions and SMS messaging notifications. Further development of this novel integrated and sustainable solution will add another tool for dealing with pest birds. Full article

Objectives: to examine the nature and context of discriminatory experiences among adolescents in Spain. Methods: A mixed study of discourse content analysis in 1000 randomly selected Spanish adolescents aged 12 to 16 years stratified by age, gender and territorial distribution. Data were analyzed to identify perpetrators, actions, and locations of discrimination. Results: Overall, 66% of adolescents reported witnessing or experiencing discrimination, primarily manifested through teasing, insults, and harassment. Peers were identified as the main perpetrators (73.9%), with schools being the primary context (69.4%) where discrimination occurs. Discrimination often lacked clear reasons (27.78%), but ethnicity (23.83%) and physical appearance (22.51%) were the most common factors, followed by gender (5.99%) or academic/ability issues (5.99%) or having an illness or developmental disorder (5.41%). Conclusions: Discrimination among adolescents is frequent, with racism and rejection of minority groups as the main causes. The findings underscore the need for interventions to address discriminatory behaviors in schools and broader society, with implications for adolescent well-being and mental health. Full article

As in many other countries, baseline data concerning the linguistic development of bilingual children in Sweden are lacking, and suitable methods for identifying developmental language disorder (DLD) in bilinguals are lacking as well. This study presents reference data from 108 typically developing (TD) Turkish/Swedish-speaking children aged 4;0–8;1, for a range of language tasks developed specifically for the assessment of bilinguals (LITMUS test battery, COST Action IS0804). We report on different types of nonword repetition (NWR) tasks (language-specific and language-independent), receptive and expressive vocabulary (Cross-Linguistic Lexical Tasks, CLTs), and narrative macrostructure comprehension and production (Multilingual Assessment Instrument for Narratives, MAIN) in Turkish, the children’s home language, and in Swedish, the language of schooling and society. Performance was investigated in relation to age, language exposure, type of task, and (for NWR and narratives) vocabulary size. There was a positive development with age for all tasks, but effects of language exposure and vocabulary size differed between tasks. Six bilingual Turkish/Swedish children with DLD were individually compared to the TD children. TD/DLD performance overlapped substantially, particularly for NWR, and more so for the production than the comprehension tasks. Surprisingly, the discriminatory potential was poor for both language-specific and language-independent NWR. DLD case studies underscored the importance of interpreting language scores in relation to exposure history, and the need for an increased emphasis on functional language skills as reported by parents and teachers when assessing and diagnosing DLD in bilinguals. Full article

Organizations play an essential role in fostering a diverse and inclusive work environment. Despite attempts to encourage gender diversity in the workplace, the construction industry in Australia remains one of the most male-dominated industries. Existing research tends to focus on identifying barriers to gender equality and women’s career development, with limited exploration of organizations’ current initiative implementation. To fill this research gap, this study aims to examine how organizations implement initiatives affecting gender equality and women’s career development in the Australian construction industry. This study applied the women’s empowerment framework and conducted a thematic analysis of diversity, inclusion, and equality policies, strategies, action plans, corporate reports, annual reports, and websites within the context of gender equality and women’s career development in construction companies. Through a comprehensive analysis, the study identifies prevalent practices and initiatives related to gender equality initiatives in the construction industry, synthesizing them into six themes: flexible working arrangements, inclusive and anti-discriminatory culture, promoting career development, recruitment, and promotion, shared caring responsibility, and strategic commitments. The findings also revealed areas for improvement, giving recommendations on how to further empower women in the construction industry through enhanced gender diversity initiatives. This study sheds light on the current state of gender diversity and inclusion efforts within construction companies and provides practical recommendations for policymakers, industry stakeholders, and organizational leaders who seek to foster more inclusive and equitable work environments. Full article

Trans people face substantial barriers to care worldwide. In Greece, limited evidence regarding trans health and actions to improve accessibility in healthcare services is available. This study aims to identify barriers to care for transgender populations in order to discuss the potential gaps in healthcare providers’ training in this direction. A scoping review was conducted in PubMed. Study eligibility criteria included: (a) reporting on at least one barrier to care for trans individuals or at least one educational need for healthcare providers; (b) free full text availability; and (c) publishing from 2015 and afterwards. Discrepancies in study inclusion were discussed between the research team until consensus was reached. Out of 560 identified references, 69 were included in this study, with only three reporting empirical research from Greece. Several individual-, interpersonal-, and institutional-level barriers to healthcare for trans individuals were identified. These included discriminatory treatment by healthcare providers, a lack of knowledgeable providers trained on trans-specific healthcare issues, lack of trusted and safe healthcare environments, health coverage-related issues, and healthcare systems that do not take into account particular transgender health issues during care provision. Improving access to care for transgender people is a multidimensional issue that should be addressed at the societal, healthcare, and research levels. Actions for future professional education initiatives should focus on respecting transgender identity, protecting confidentiality, creating trusted provider–patient relationships, and providing sufficient competency on trans-specific healthcare issues. Full article

In literature relevant to this topic, attention is mainly paid to the qualitative and quantitative identification of defects in housing construction, and the factors that cause these defects. There is a research gap regarding the quantitative relationships between factors and defects, and the identification of factors that have a decisive impact on the occurrence of defects. The authors’ contribution to research regarding quality management in construction investments involves the identification of defects in residential buildings, identification of factors that generate construction defects occurring at various stages of the investment process, and also the assessment of their discriminatory power. This analysis used the results of technical inspections of buildings carried out in Poland in 2017–2020 in the Lower Silesia region. The study of the factors that influence quality in housing construction was carried out using the diagnostic survey method and the survey technique. Discriminant analysis was used for the calculations, with a number of influence factors being found. The following factors have the greatest discriminatory power: C1—a lack of internal control of design documentation before the start of the construction of the facility; C15—a lack of stability of the team (high staff turnover) that conducts contract tenders; C30—a lack of executive potential for preparing the facility for technical acceptance. Identifying the relationships between factors and quality, measured by the number and type of defects, will constitute the basis for developing procedures for conducting and controlling construction works and taking appropriate preventive actions in the form of employee training. Full article

In this article, we outline a transnational project shaped by Sustainable Development Goal (SDG) 10: “Reduce inequality within and among countries”. SDG 10 provides a cross-cutting approach insofar as the targets refer to income inequality, discriminatory practices and policies, migration policies, and development aid and assist researchers as well as policymakers and community leaders with implementation. The project builds on two online courses for researchers early in their careers: one that covers the research context and one that covers preparing a research question and approach. Community-based participatory research (CBPR) is an impactful method of exploring social inequalities and applying research to solve practical problems. For students to learn the basic steps of CBPR, a workshop was conducted with a rural NGO in India that included researchers from three countries, staff members, and community members. The topic, “waste management”, was chosen by the local NGO and integrated with the university program through a CBPR methodology workshop. This article describes the background, learning process, and results of the participatory research workshop and focuses on the collaboration of students, staff, and community members as well as the application of research for action. Full article

Family caregivers and care providers are increasingly becoming more distressed and reaching a breaking point within current systems of care. First Nations family caregivers and the health and community providers employed in First Nations communities have to cope with colonial, discriminatory practices that have caused intergenerational trauma and a myriad of siloed, disconnected, and difficult-to-navigate federal-, provincial/territorial-, and community-level policies and programs. Indigenous participants in Alberta’s Health Advisory Councils described Indigenous family caregivers as having more difficulty accessing support than other Alberta caregivers. In this article, we report on family caregivers’, providers’, and leaders’ recommendations to support First Nations family caregivers and the health and community providers employed in First Nations. We used participatory action research methods in which we drew on Etuaptmumk (the understanding that being in the world is the gift of multiple perspectives) and that Indigenous and non-Indigenous views are complementary. Participants were from two First Nation communities in Alberta and included family caregivers (n = 6), health and community providers (n = 14), and healthcare and community leaders (n = 6). Participants advised that family caregivers needed four types of support: (1) recognize the family caregivers’ role and work; (2) enhance navigation and timely access to services, (3) improve home care support and respite, and (4) provide culturally safe care. Participants had four recommendations to support providers: (1) support community providers’ health and wellbeing; (2) recruit and retain health and community providers; (3) improve orientation for new providers; and (4) offer providers a comprehensive grounding in cultural awareness. While creating a program or department for family caregivers may be tempting to address caregivers’ immediate needs, improving the health of First Nations family caregivers requires a population-based public health approach that focuses on meaningful holistic system change to support family caregivers. Full article

In this paper we hypothesize that the practices that prevailed during the pandemic period in relation to the right to parks were related to traditional urban discriminatory policies that need to be changed. We also argue that, in some cases, the residents themselves treated the parks as common living spaces by protecting them from neoliberal grabbing policies that deprive residents of greenery and infringe on the right to the city and to nature. With this in mind, we proceeded with research on the city of Athens. We investigated two urban green parks, the first was “Lofos Philopappou”, which is one of the most important parks in the city, as it is one of the largest green spaces in the city center and includes some of the most important ancient monuments. The second park was “Antonis Tritsis”, which is the largest park in Athens Metropolitan Area and one of the few high green spaces in the western suburbs. In the framework of this study, we investigated the attitudes and the actions of visitors and groups regarding these parks, the urban social movements, and local struggles and initiatives that are active in the public green parks, together with participation through the commons. We also investigated management policies and attempts to privatize them. The research methods that were used were participant observation in the studied parks, semi-structured interviews with people or groups that used the public urban green parks on a regular basis, noting the narratives they produced, and questionnaires given to visitors who actively used the urban parks. In conclusion, policies implemented within public parks were found to prevent the integration of public green spaces in the daily lives of residents and the active participation of residents in decisions concerning the green extensions of their neighborhoods. In this way, a part of society is deprived of the ability to maintain continuous contact with nature and green parks. Full article

We perceive contestations between science, education and women’s engagement and have raised disruptions in their act of knowing and mobility in science education. This study explored science educators’ views, beliefs and actions of reproduction and subversion of gender stereotyping at a teacher education college in Nigeria. Six science educators were selected based on comprehensive gender information that facilitated conduction of the study. The six educators were purposively selected out of 11 educators who completed and returned the questionnaire. A qualitative approach and case study framed the research using instruments such as questionnaires, interviews, and classroom observation schedules. Thematic analysis and coding were done. Educators consciously and unconsciously reproduced gender stereotypes beliefs and practices. Educators explicitly and implicitly engaged in unequal distribution of cognitive activities amongst pre-service teachers influenced by their practice of cultural norms and patriarchal ideology. The findings revealed multiple oppressions females faced, contradictory science classrooms, and political and democratic classroom space for negotiating and renegotiating discriminatory classroom beliefs, perception and views of educators during science engagements. However, several possibilities such as political advocacy, productive activism and transformative resistance for educators to re-negotiate discriminatory gendered space through constructive gender equality awareness for freedom and intellectual growth in science education could be emancipatory possibilities. Full article

During the last two years, the pandemic has dominated the public attention and debate around the world, centering on socio-economic aspects and having camouflaged other social, cultural and even environmental issues. This study sought to analyze ethno-racial discrimination processes, identifying significant events in Portugal during the period of the current global crisis. We utilized document analysis of national and international reports produced in the last five years, complementing with secondary statistical data and the analysis of online news and users’ comments published in national media during the last two years. The results show that, although there has been a development in Portuguese legislation and in anti-discrimination measures, there has been an increase in racist and xenophobic phenomena in Portugal. Citizens’ perceptions, indicators and reports from official bodies show evidence of discriminatory behavior. Additionally, within this framework, we see a greater political presence of extreme right-wing movements, as well as an increase in hate speech in online news comments. Thus, although there is an awareness of the seriousness of these phenomena, there is an urgent need for actions against racial and ethnic intolerance and greater effective measures for ideological crimes. Full article