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35 pages, 1587 KB  
Systematic Review
A Review of Subjective Indoor Air Quality Assessment in Non-Residential Buildings: Current Trends and Recommendations
by Quinten Carton, Douaa Al-Assaad, Jakub Kolarik and Hilde Breesch
Buildings 2026, 16(3), 486; https://doi.org/10.3390/buildings16030486 (registering DOI) - 24 Jan 2026
Abstract
Survey campaigns in non-residential buildings show that occupants are often dissatisfied with the indoor environmental quality (IEQ), including the indoor air quality (IAQ) conditions. Occupant-centric controls (OCCs) have the potential to improve occupants’ satisfaction with IAQ and thermal comfort. Currently, applications of OCC [...] Read more.
Survey campaigns in non-residential buildings show that occupants are often dissatisfied with the indoor environmental quality (IEQ), including the indoor air quality (IAQ) conditions. Occupant-centric controls (OCCs) have the potential to improve occupants’ satisfaction with IAQ and thermal comfort. Currently, applications of OCC systems with IAQ perceptions are limited due to a lack of a suitable modelling approach to predict occupants’ subjective IAQ assessment. In addition, a comprehensive overview of possible confounding variables for subjective IAQ in non-residential buildings is missing. This paper presents a systematic review of 46 papers on subjective IAQ assessments during field investigations in non-residential buildings. The following characteristics of the studies are examined: (1) the study context, (2) study and survey type, (3) dataset and sample size, (4) subjective IAQ assessment scales, (5) analysis and modelling techniques, and (6) associated variables. The review identified 46 different assessment scales and 20 different analysis techniques, respectively, indicating a lack of uniformity across the studies. The vast majority of studies were conducted in classrooms or offices. Other non-residential buildings, such as hospitals and sports halls, were underrepresented. Moreover, most of the studies failed to elaborate on the choice of a statistical technique and to report on the required sample size, compromising the validity of the statistical results. Furthermore, the review highlighted the limited scope of the subjective IAQ assessment analysis, with half of the reviewed studies investigating no more than four different variables. Lastly, only three of the reviewed papers focused on determining an accurate predictive model for subjective IAQ assessment. Full article
(This article belongs to the Topic Indoor Air Quality and Built Environment)
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28 pages, 3422 KB  
Article
Implementation of Integrated Control Systems Projects in Companies Focused on Industry 4.0: Opportunities and Challenges in Brazil
by Auro de Jesus Cardoso Correia, Leandro Simplício Silva, Josiane Lima de Araújo, Jose Celso Contador, José Luiz Contador, Guilherme Henrique de Magalhães, Rogerio Glaser Prado, Walter Cardoso Satyro and Mauro de Mesquita Spinola
Technologies 2026, 14(2), 78; https://doi.org/10.3390/technologies14020078 (registering DOI) - 23 Jan 2026
Abstract
Integrated control systems (Supervisory Control and Data Acquisition–SCADA and Manufacturing Execution Systems—MES) constitute the backbone of Industry 4.0; however, research on their implementation remains scarce. This study analyzes the opportunities and challenges of modernizing these systems within the context of the Brazilian industry. [...] Read more.
Integrated control systems (Supervisory Control and Data Acquisition–SCADA and Manufacturing Execution Systems—MES) constitute the backbone of Industry 4.0; however, research on their implementation remains scarce. This study analyzes the opportunities and challenges of modernizing these systems within the context of the Brazilian industry. A survey of 101 experts was conducted, with results analyzed via Friedman and Holm–Sidak nonparametric tests to establish a clear hierarchy of factors. Findings reveal that while economic efficiency, productivity gains, and real-time remote access represent the most significant opportunities, they are countered by critical structural challenges: obsolete machinery and inadequate infrastructure. These challenges significantly inflate implementation costs and highlight the reality of technological obsolescence that is typical of emerging economies. By applying the Resource-Based View (RBV), this research frames digital integration as a strategic competitive capability rather than a mere technical upgrade. Practically, the study provides a roadmap for industrial leaders to balance digital agility expectations with pragmatic operational constraints. These insights offer a foundation for successful digital transformation, delivering actionable value for academics, industrial managers, and policymakers. Full article
13 pages, 1062 KB  
Article
Identification Pathogenicity Distribution and Chemical Control of Rhizoctonia solani Causing Soybean Root Rot in Northeast China
by Shuni Wang, Jinxin Liu, Chen Wang, Jianzhong Wu, Zhongbao Shen and Yonggang Li
Agronomy 2026, 16(3), 281; https://doi.org/10.3390/agronomy16030281 - 23 Jan 2026
Abstract
Soybean root rot caused by Rhizoctonia solani is a yield-limiting disease in Northeast China, particularly under continuous monoculture and cool climatic conditions. Despite its agronomic impact, the epidemiology and fungicide resistance profile of the pathogen remain inadequately characterized. In this study, a comprehensive [...] Read more.
Soybean root rot caused by Rhizoctonia solani is a yield-limiting disease in Northeast China, particularly under continuous monoculture and cool climatic conditions. Despite its agronomic impact, the epidemiology and fungicide resistance profile of the pathogen remain inadequately characterized. In this study, a comprehensive survey conducted in Heilongjiang Province yielded 990 pathogenic isolates belonging to 11 fungal species. Among them, 55 strains were identified as R. solani based on combined morphological and molecular analyses. These isolates induced typical symptoms of root and stem browning with constriction. Pathogenicity tests on 30 R. solani isolates indicated that 83.3% were highly pathogenic. The pathogen exhibited a distinct geographic distribution, with the highest percentage of pathogen isolation recorded in Jiamusi (26.6%), which accounted for 61.8% of all R. solani isolates. In vitro fungicide sensitivity assays demonstrated that fludioxonil and prochloraz were highly effective (EC50 < 0.0050 µg·mL−1), whereas resistance was observed to tebuconazole, difenoconazole, pyraclostrobin, and carbendazim. Pot experiments confirmed that fludioxonil seed treatment (15 g a.i./100 kg seeds) provided superior control efficacy (63.07%) compared to prochloraz (46.85%). These findings establish R. solani as a dominant causal agent of soybean root rot in the region and support the prioritized use of fludioxonil for sustainable disease management. By elucidating the pathogenicity, distribution, and resistance patterns of R. solani, this study provides critical insights for controlling soybean root rot in cold-climate production systems and facilitates the development of targeted management strategies. Full article
(This article belongs to the Special Issue Recent Advances in Legume Crop Protection—2nd Edition)
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19 pages, 1323 KB  
Article
Modernisation Potential of Civil Defence Shelters: Compliance Assessment and Risk-Based Retrofit Strategy in Poland
by Marlena Anna Jurczak and Maria Tunkiewicz
Appl. Sci. 2026, 16(2), 1144; https://doi.org/10.3390/app16021144 - 22 Jan 2026
Abstract
Civil defence shelters constitute an essential component of safety systems in emergency situations. The aim of this article is to assess the modernization potential of existing civil defence shelters in Poland, using a representative facility located in Olsztyn (Poland) as a case study. [...] Read more.
Civil defence shelters constitute an essential component of safety systems in emergency situations. The aim of this article is to assess the modernization potential of existing civil defence shelters in Poland, using a representative facility located in Olsztyn (Poland) as a case study. The analysis is based on a review of the current legal framework and identification of legislative gaps that affect the implementation of effective protective solutions. Within the case study, a detailed technical assessment of the protective structure was carried out, focusing on construction, protection against radiation and contamination, fire safety, and user ergonomics. Based on this assessment, a comparative analysis was performed between the surveyed facility and current as well as proposed technical requirements. The results revealed partial compliance with regulations while identifying significant deficiencies. To address these issues, measures such as replacing ventilation units with modern systems featuring automatic control, installing EI120-certified doors, improving emergency exit dimensions, and adding emergency lighting were proposed. Subsequently, risks associated with modernization were identified in accordance with ISO 31000. The findings highlight the need for systematic modernization of existing protective structures, clarification of legal regulations, and increased investment, which are key conditions for improving civilian safety. Full article
(This article belongs to the Section Civil Engineering)
45 pages, 15149 KB  
Review
A New Era in Computing: A Review of Neuromorphic Computing Chip Architecture and Applications
by Guang Chen, Meng Xu, Yuying Chen, Fuge Yuan, Lanqi Qin and Jian Ren
Chips 2026, 5(1), 3; https://doi.org/10.3390/chips5010003 - 22 Jan 2026
Abstract
Neuromorphic computing, an interdisciplinary field combining neuroscience and computer science, aims to create efficient, bio-inspired systems. Different from von Neumann architectures, neuromorphic systems integrate memory and processing units to enable parallel, event-driven computation. By simulating the behavior of biological neurons and networks, these [...] Read more.
Neuromorphic computing, an interdisciplinary field combining neuroscience and computer science, aims to create efficient, bio-inspired systems. Different from von Neumann architectures, neuromorphic systems integrate memory and processing units to enable parallel, event-driven computation. By simulating the behavior of biological neurons and networks, these systems excel in tasks like pattern recognition, perception, and decision-making. Neuromorphic computing chips, which operate similarly to the human brain, offer significant potential for enhancing the performance and energy efficiency of bio-inspired algorithms. This review introduces a novel five-dimensional comparative framework—process technology, scale, power consumption, neuronal models, and architectural features—that systematically categorizes and contrasts neuromorphic implementations beyond existing surveys. We analyze notable neuromorphic chips, such as BrainScaleS, SpiNNaker, TrueNorth, and Loihi, comparing their scale, power consumption, and computational models. The paper also explores the applications of neuromorphic computing chips in artificial intelligence (AI), robotics, neuroscience, and adaptive control systems, while facing challenges related to hardware limitations, algorithms, and system scalability and integration. Full article
15 pages, 436 KB  
Article
Artificial Intelligence in Sustainable Marketing: How AI Personalization Impacts Consumer Purchase Decisions
by Enas Alsaffarini and Bahaa Subhi Awwad
Sustainability 2026, 18(2), 1123; https://doi.org/10.3390/su18021123 - 22 Jan 2026
Abstract
The study explores how consumer buying behavior is influenced by artificial intelligence (AI) personalization, with a specific focus on responsible and sustainability-aligned digital marketing. Using an explanatory sequential mixed-methods design, the study analyzes a quantitative survey and qualitative interviews. Results show that purchase [...] Read more.
The study explores how consumer buying behavior is influenced by artificial intelligence (AI) personalization, with a specific focus on responsible and sustainability-aligned digital marketing. Using an explanatory sequential mixed-methods design, the study analyzes a quantitative survey and qualitative interviews. Results show that purchase behavior is strongly affected by exposure to AI messages—especially when recommendations are relevant, timely, and emotionally appealing—and by trust in AI, while perceived lack of trust inhibits purchasing. Qualitative findings underscore affective responses alongside ethical concerns, perceived transparency, and perceived control over data. Overall, the study shows that effective personalization depends not only on algorithmic sophistication but also on users’ sense of relevance and autonomy and on ethical data governance. The conclusions highlight sustainability-consistent implications for marketers: increase data transparency, segment customers by privacy sensitivity, and adopt accountable, consent-based personalization to build durable trust and loyalty. Future research should examine longitudinal effects and cultural differences, acknowledging limits of small purposive qualitative samples for generalization and exploring how consumer trust, ethical perceptions, and responses to AI personalization evolve over time. Full article
(This article belongs to the Special Issue Sustainable Digital Marketing Policy and Studies of Consumer Behavior)
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16 pages, 582 KB  
Article
Soft Tissue Stiffness and Functional Knee Outcomes in Female Handball Players Following a Knee Injury: A Cross-Sectional Study
by Joanna Mencel, Alicja Noculak and Tomasz Sipko
J. Clin. Med. 2026, 15(2), 891; https://doi.org/10.3390/jcm15020891 (registering DOI) - 22 Jan 2026
Abstract
Background/Objectives: The aim of our study was to evaluate the transverse stiffness of selected soft tissues in the knee joint region on the previously injured and uninjured sides of female handball players and non-athlete women, in the lying and standing positions, and [...] Read more.
Background/Objectives: The aim of our study was to evaluate the transverse stiffness of selected soft tissues in the knee joint region on the previously injured and uninjured sides of female handball players and non-athlete women, in the lying and standing positions, and to investigate the relationship between stiffness, age, sporting practice, and clinical assessments of the knees. Methods: A total of 25 young female handball players (the SPORT group) and 27 healthy non-athletic individuals (the CONTROL group) were examined. The MyotonPRO device was used to measure the stiffness of the patellar tendon (PT), rectus femoris (RF), and biceps femoris (BF) muscles on both sides and in both positions. The function of the knee joints was clinically assessed using the Knee Outcome Survey—Sports Activities Scale and the Lysholm Knee Scoring Scale. Results: ANOVA indicated a significant effect of group (p < 0.003) on the PT’s stiffness, and a significant effect of position (p < 0.0001) on the PT, RF, and BF muscle stiffness. The SPORT group demonstrated significantly higher PT transverse stiffness when lying down (p < 0.01), but not when sitting up (p > 0.05), compared to the CONTROL group. Significant negative correlations were found between PT stiffness and both clinical scales in the SPORT group (rho from −0.39 to −0.71, p < 0.05). Conclusions: In female handball players, only the patellar tendon transverse stiffness was higher than in the control group. While this higher stiffness could indicate an adaptive rebuilding process, it was negatively correlated with the clinical assessment of joint function, meaning poorer knee joint function. Full article
(This article belongs to the Section Sports Medicine)
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12 pages, 1655 KB  
Article
Impact of Integrated Control Interventions on Sandfly Populations in Human and Canine Visceral Leishmaniasis Control in Araçatuba, State of São Paulo, Brazil
by Keuryn Alessandra Mira Luz-Requena, Tania Mara Tomiko Suto, Osias Rangel, Regina Célia Loverdi de Lima Stringheta, Thais Rabelo Santos-Doni, Lilian Aparecida Colebrusco Rodas and Katia Denise Saraiva Bresciani
Insects 2026, 17(1), 125; https://doi.org/10.3390/insects17010125 - 21 Jan 2026
Abstract
Visceral leishmaniasis (VL) is a serious vector-borne disease affecting humans and dogs, posing major public health challenges in endemic regions. Control efforts often target sandfly vectors, whose larvae and pupae develop in soil. Environmental management, such as removing organic matter, reducing moisture, and [...] Read more.
Visceral leishmaniasis (VL) is a serious vector-borne disease affecting humans and dogs, posing major public health challenges in endemic regions. Control efforts often target sandfly vectors, whose larvae and pupae develop in soil. Environmental management, such as removing organic matter, reducing moisture, and pruning vegetation, aims to limit breeding sites and reduce sandfly populations. This study evaluated the impact of integrated interventions on sandfly behavior in priority areas for VL control in Araçatuba, São Paulo, Brazil. The control strategy combined environmental management, canine surveys, and educational actions across seven local work areas (LWAs). Between 2019 and 2021, CDC-type light traps were installed in intra- and peridomiciliary settings at twelve properties in LWA 5. Spatial risk analysis for canine transmission was conducted in LWAs 3 and 5 using a Generalized Additive Model, with results presented as spatial odds ratios. Vector prevalence was analyzed using negative binomial regression compared to historical municipal data. Intervention coverage averaged 52.91% of visited properties (n = 15,905), ranging from 48% to 76.8% across LWAs. Adherence to environmental management exceeded 85%. Of the 150 sandflies collected, 98.67% were Lutzomyia longipalpis and 1.33% Nyssomyia neivai. A 6% reduction in vector density was observed compared with historical data, although this difference was not statistically significant. Spatial risk varied among LWAs, indicating heterogeneous transmission levels. These findings suggest that integrated environmental and educational interventions may contribute to reducing vector density and that identifying priority areas tends to support surveillance and the effectiveness of disease control actions. Full article
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25 pages, 797 KB  
Review
Metabolic Bone Disease in Captive Flying Foxes: A Conceptual Framework and Future Perspectives
by Diana Faim, Isabel Pires and Filipe Silva
Metabolites 2026, 16(1), 87; https://doi.org/10.3390/metabo16010087 - 21 Jan 2026
Abstract
In Pteropus spp., metabolic bone disease has been consistently associated with fruit-based diets that are deficient in calcium, vitamin D precursors, and protein, as well as limited ultraviolet B (UVB) exposure, as reported in zoological surveys and clinical observations. Comparative mammalian physiology suggests [...] Read more.
In Pteropus spp., metabolic bone disease has been consistently associated with fruit-based diets that are deficient in calcium, vitamin D precursors, and protein, as well as limited ultraviolet B (UVB) exposure, as reported in zoological surveys and clinical observations. Comparative mammalian physiology suggests that dysregulation of the endocrine axis involving parathyroid hormone (PTH), fibroblast growth factor 23 (FGF23), calcitonin, and calcitriol may contribute to disease development, although direct species-specific endocrine data in flying foxes remain scarce. This narrative review synthesizes current knowledge from published zoological reports, clinical observations, and comparative mammalian physiology regarding the etiology, pathophysiology, and clinical expression of metabolic bone disease in captive flying foxes. Much of the available evidence is derived from juvenile Pteropus vampyrus, and its applicability to other Pteropus species remains to be fully established. The limited availability and consistency of existing data, together with the scarcity of controlled experimental and longitudinal studies, necessarily constrain the conclusions that can be drawn. Nevertheless, this review highlights key nutritional and environmental risk factors and summarizes evidence-informed preventive management strategies to improve skeletal health and welfare in managed Pteropus populations. Full article
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20 pages, 1684 KB  
Article
Why Our Youth Vape?—A Trend Analysis Based on Cross-Sectional Annual Surveys of Middle and High School Students in the U.S.
by Tianyuan Guan, Zhaochong Yu, Preethi Bhosle, Chen Li, Kai Sun and Marepalli B. Rao
Medicina 2026, 62(1), 223; https://doi.org/10.3390/medicina62010223 - 21 Jan 2026
Abstract
Background and Objectives: E-cigarette use among middle and high school students steadily increased in the last decade, raising significant public health concerns. It is argued that e-cigarettes contain a lower level of toxicants than combustible tobacco cigarettes. This perception has contributed to [...] Read more.
Background and Objectives: E-cigarette use among middle and high school students steadily increased in the last decade, raising significant public health concerns. It is argued that e-cigarettes contain a lower level of toxicants than combustible tobacco cigarettes. This perception has contributed to the growing popularity of e-cigarettes among youth. However, lower level of toxicants does not mean addiction is less likely. In this study, we examine trends in the usage of electronic cigarettes among middle and high school students in the U.S. from 2018 to 2023, compare these patterns with traditional cigarette use over the same period and population, and explore the underlying reasons driving e-cigarette use within this demographic. Understanding patterns and motivations are essential for developing effective prevention and intervention strategies. Materials and Methods: Data were derived from the National Youth Tobacco Survey (NYTS), administered by the Centers for Disease Control and Prevention (CDC). Population-level estimates and standard errors were calculated to facilitate comparisons across subgroups and time points. Results: A declining trend in e-cigarette use was observed over the study period. The proportion of students who reported exclusive e-cigarette use was significantly higher than that of those who used combustible cigarettes exclusively. Among reported motivations, anxiety consistently ranked among the top three reasons for vaping for current users. Conclusions: The downward trend in youth e-cigarette experimentation is encouraging. However, the period from 2020 to 2023, which includes the COVID-19 pandemic (2020 and 2021) era, may have impacted usage patterns. Alarmingly, the number of students who vape exclusively is approximately five times greater than that of those who smoke only cigarettes. This finding contradicts claims by e-cigarette manufacturers that their products facilitate smoking cessation. Further rising e-cigarette smoking exclusively is of public health concern, which warrants targeted intervention. Full article
(This article belongs to the Section Epidemiology & Public Health)
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12 pages, 1300 KB  
Article
Safety, Feasibility, and User Experience of Automated Insulin Delivery Systems During Hajj (Muslim Pilgrimage)
by Mohammed E. Al-Sofiani
J. Clin. Med. 2026, 15(2), 860; https://doi.org/10.3390/jcm15020860 - 21 Jan 2026
Abstract
Background/Objectives: Performing Hajj, the annual Islamic pilgrimage to Mecca and one of the world’s largest mass gatherings, involves considerable physical exertion in high temperatures and presents unique challenges for people with type 1 diabetes (PWT1D). We examined the feasibility, safety, and user experience [...] Read more.
Background/Objectives: Performing Hajj, the annual Islamic pilgrimage to Mecca and one of the world’s largest mass gatherings, involves considerable physical exertion in high temperatures and presents unique challenges for people with type 1 diabetes (PWT1D). We examined the feasibility, safety, and user experience of automated insulin delivery (AID) systems during Hajj. Methods: This mixed-methods study evaluated six PWT1D who used an AID pump (2 MiniMed 780G, 2 Medtrum, 1 OmniPod 5, and 1 Open-source AID) while performing Hajj in 2024–2025. Pump and CGM-derived metrics were compared across pre-Hajj, during Hajj, and post-Hajj periods. A structured survey captured participants’ experiences, challenges, and recommendations for AID use during Hajj. Results: The average percent time in range (TIR) remained stable from pre- to during Hajj (54.98 to 54.18, p > 0.05) and significantly increased post-Hajj (62.62, p < 0.05). The percent time above range (TAR > 180) and Glycemia Risk Index significantly decreased from pre- to post-Hajj (28.34 to 26.28 and 50.3 to 19.3, respectively, both p < 0.05). The percent time below range (TBR) remained low (<1%) across the three periods with no incidence of acute diabetes-related complications. Participants emphasized increased confidence and peace of mind with AID use and reported challenges related to heat exposure, prolonged walking, and lack of awareness regarding diabetes technology among HCPs. Conclusions: The use of AID during Hajj appeared to be safe and effective for PWT1D in our study, maintaining stable glycemic control under physically demanding conditions. As the first study to evaluate AID use during Hajj, our findings call for larger studies to explore the integration of diabetes technology into Hajj care protocols and highlight the need for structured pre-Hajj education for PWT1D and HCPs. Full article
(This article belongs to the Section Endocrinology & Metabolism)
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18 pages, 760 KB  
Article
It’s Not Just About Price: What Drives Gen Z to Choose Sustainable Stays?
by Neringa Vilkaite-Vaitone
Sustainability 2026, 18(2), 1075; https://doi.org/10.3390/su18021075 - 21 Jan 2026
Abstract
This study explores the factors that influence Gen Z consumers’ green purchasing behavior, addressing a gap in current research by combining the Theory of Planned Behavior, the Theory of Consumption Values, and Generational Theory, and applying them to the touristic accommodation context. Based [...] Read more.
This study explores the factors that influence Gen Z consumers’ green purchasing behavior, addressing a gap in current research by combining the Theory of Planned Behavior, the Theory of Consumption Values, and Generational Theory, and applying them to the touristic accommodation context. Based on a quantitative survey of Gen Z tourists from Spain, Norway, and Lithuania, the study examined traditional constructs of the Theory of Planned Behavior alongside subjective knowledge, environmental consciousness, perceived value, and green trust. Using Partial Least Squares Structural Equation Modeling (PLS-SEM), the results indicate a significant role for price-based functional value and emotional value in shaping Gen Z’s attitudes toward sustainable accommodation. Furthermore, subjective knowledge and environmental consciousness strengthen green trust, which in turn contributes to a more positive attitude toward sustainable touristic options. Attitude, subjective norms, and perceived behavioral control significantly predict behavioral intention, while both perceived behavioral control and behavioral intention directly influence actual purchasing behavior. The findings suggest that tourism marketers should focus on enhancing price-related and emotionally meaningful value propositions, while also fostering trust through clear communication of environmental performance. Overall, the study offers a comprehensive understanding of the drivers behind Gen Z’s sustainable accommodation choices and provides practical implications for promoting environmentally responsible tourism. Full article
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12 pages, 651 KB  
Article
Real-World Effectiveness of Seasonal Influenza Vaccines During the 2024–2025 Season: Subgroup Analyses by Virus Subtype, Time Since Vaccination, and Diagnostic Method
by Yu Jung Choi, Jungmin Lee, Joon Young Song, Seong-Heon Wie, Jacob Lee, Jin-Soo Lee, Hye Won Jeong, Joong Sik Eom, Jang Wook Sohn, Young Kyung Yoon, Won Suk Choi, Eliel Nham, Jin Gu Yoon, Ji Yun Noh, Man-Seong Park and Hee Jin Cheong
Vaccines 2026, 14(1), 102; https://doi.org/10.3390/vaccines14010102 - 21 Jan 2026
Abstract
Background/Objectives: Despite high vaccination coverage, influenza remains a public health concern in South Korea, particularly in older adults. Continuous evaluation of vaccine effectiveness (VE) is essential to optimize immunization strategies. Methods: This study evaluated seasonal influenza VE for preventing laboratory-confirmed influenza [...] Read more.
Background/Objectives: Despite high vaccination coverage, influenza remains a public health concern in South Korea, particularly in older adults. Continuous evaluation of vaccine effectiveness (VE) is essential to optimize immunization strategies. Methods: This study evaluated seasonal influenza VE for preventing laboratory-confirmed influenza using a test-negative design through a hospital-based influenza surveillance system in South Korea from 1 November 2024, to 30 April 2025. Demographic and clinical information was collected through questionnaire surveys and electronic medical records. Influenza was diagnosed using rapid antigen tests (RATs) and reverse transcription polymerase chain reaction (RT-qPCR), and vaccine effectiveness was analyzed using multivariable logistic regression. Results: In total, 3954 participants were included, with 1977 influenza-positive cases and 1977 test-negative controls. Influenza A and B accounted for 93.1% and 7.0% of cases, respectively. The adjusted overall VE was 20.4% (95% confidence interval [CI], 8.2–30.9; p = 0.002). VE was higher in adults aged 50–64 years (46.8%) than in those aged ≥65 years (18.8%). VE was 19.9% against influenza A and 45.7% against A/H3N2. VE was higher among individuals tested using RT-qPCR than among those tested using RATs (21.5% vs. 15.7%), and was also greater during the early period than during the late period (20.5% vs. 11.4%). Vaccination did not reduce influenza-associated hospitalization risk (VE, 17.3%; 95% CI, −9.3 to 37.4). A significant reduction in hospitalization risk was observed in adults aged 50–64 years (VE, 46.8%), with no significant benefit in those aged ≥65 years. Conclusions: The 2024–2025 seasonal influenza vaccine provided moderate protection against laboratory-confirmed influenza in adults, with higher effectiveness in those aged 50–64 years. Full article
(This article belongs to the Section Influenza Virus Vaccines)
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12 pages, 915 KB  
Article
Locus of Control and Its Association with Depression, Anxiety, and Stress Among Mexican University Students: A Cross-Sectional Study
by Magnolia Guerrero Castillo, Maria Fernanda Martinez Gonzalez, Andrea Alejandra Escalera Jasso, Luis Adrian Alvarez Lozada, Arcelia Lizbeth Torres Pérez, Alejandro Quiroga Garza, Rosa Ivett Guzman Avilan, Diego Escamilla Magaña, Rodrigo Bravo Garcia, Martha Lilia Pérez Sosa, Yelyann Magory Márquez González, Rodrigo Enrique Elizondo Omaña and Guillermo Jacobo Baca
Int. J. Environ. Res. Public Health 2026, 23(1), 130; https://doi.org/10.3390/ijerph23010130 - 21 Jan 2026
Abstract
Locus of control is a psychological construct that influences how individuals perceive their ability to manage life events. Although its relationship with mental health has been widely studied, limited evidence exists among Latin-American university student populations. To assess the association between locus of [...] Read more.
Locus of control is a psychological construct that influences how individuals perceive their ability to manage life events. Although its relationship with mental health has been widely studied, limited evidence exists among Latin-American university student populations. To assess the association between locus of control and symptoms of depression, anxiety, and stress among university students in Nuevo León, Mexico. A cross-sectional, analytical study was conducted using data from the Healthy Lifestyle Promotion Program at the Universidad Autónoma de Nuevo León. A total of 815 students completed a digital survey assessing sociodemographic variables, DASS-21, and Burger’s Locus of Control Scale. Participants had a mean age of 19.8 ± 3.4, 57.1% were women. The prevalence of symptoms was 64.4% for depression, 55.8% for stress, and 74.1% for anxiety. Women exhibited higher severity across all dimensions (p < 0.001). Locus of control scores decreased significantly as the severity of depression, stress, and anxiety increased, particularly in moderate to extremely severe categories. An external locus of control was consistently associated with higher frequency of severe psychological symptoms. An external locus of control was strongly associated with poorer mental health outcomes. Strengthening internal locus of control may enhance resilience, reduce psychological distress, and improve academic performance. Full article
(This article belongs to the Special Issue Health Behaviors and Mental Health Among College Students)
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27 pages, 1017 KB  
Article
Use and Perceived Helpfulness of Different Intervention Strategies in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Depression
by Marie Celine Dorczok, Nilufar Mossaheb, Gloria Mittmann, Marina F. Thomas, Lucie Bartova, Beate Schrank and Verena Steiner-Hofbauer
J. Clin. Med. 2026, 15(2), 849; https://doi.org/10.3390/jcm15020849 (registering DOI) - 20 Jan 2026
Abstract
Background: Patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) or depression both frequently report debilitating exhaustion, yet the two conditions differ in their etiological and diagnostic clarity, and clinical management. This study aimed to examine differences in the use and perceived helpfulness of a [...] Read more.
Background: Patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) or depression both frequently report debilitating exhaustion, yet the two conditions differ in their etiological and diagnostic clarity, and clinical management. This study aimed to examine differences in the use and perceived helpfulness of a broad range of conventional treatments and complementary interventions, including nutritional approaches, between patients with ME/CFS and depression. Methods: A cross-sectional online survey was conducted in 2024. A total of 819 participants self-identified as having either ME/CFS (n = 576) or depression (n = 243). Participants (80% female) reported their use and perceived helpfulness of 52 treatments and interventions, encompassing behavioral therapies, medications, and dietary supplements. Group differences were examined using multivariate analyses of variance and covariance (MANOVA/MANCOVA). Open-ended responses were analyzed descriptively using thematic grouping and frequency counts. Results: Participants with depression most commonly reported the use of psychotherapy (M = 2.49, SD = 1.00) and antidepressant medication (M = 2.44, SD = 2.30), and they rated fewer interventions as helpful compared to participants with ME/CFS. In contrast, participants with ME/CFS reported a significantly broader engagement with diverse intervention modalities, particularly pacing (M = 2.73, SD = 0.80) and dietary supplements (M = 2.43, SD = 1.09), and perceived many of them as helpful. Group differences remained significant after controlling for age, gender, and whether treatment was medically recommended. Supplements targeting energy metabolism (e.g., CoQ10, NADH) were especially favored among ME/CFS participants. Conclusions: Findings suggest that participants with ME/CFS tend to adopt an exploratory and expansive intervention approach, potentially reflecting the lack of standardized guidelines and limited effectiveness of available treatment options. Participants with depression, in contrast, appeared to follow more guideline-concordant, evidence-based treatment pathways. Taken together, the findings point to a need for further development and evaluation of empirically supported, patient-centered treatment and intervention strategies for ME/CFS and suggest differences in clinical care structures between ME/CFS and depression. Full article
(This article belongs to the Special Issue Innovations in the Treatment for Depression and Anxiety)
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