Search Results (282)

This work presents the first study addressing two-dimensional numerical simulations of acoustic wave scattering involving a simplified human body model placed inside an enclosed cabin. The simulations utilise the µ-diff backscattering algorithm in MATLAB, which is suitable for modeling frequency-domain interactions with multiple scatterers under penetrable boundary conditions. The body is represented as a cluster of penetrable, tangent circular cylinders with acoustic properties mimicking muscle, fat, bone, and clothing layers. Hidden PVC cylinders are embedded to simulate concealed objects. Several configurations were examined, varying the number of PVC inclusions (two to four), the frequency range, and the presence of an absorbing cabin wall. Sound pressure level (SPL) distributions around the body and at a 1 m distance were analysed. Polar plots reveal distinct differences between the baseline body model and those incorporating PVC inclusions. The most pronounced effects occur near 160 Hz, where an absorbing wall is present within the acoustic enclosure. The presence of an absorbing wall modifies wave behaviour, producing enhanced directional attenuation. The results demonstrate how object composition, spatial arrangement, and enclosure geometry influence acoustic backscattered fields. These findings highlight the potential of wave-based numerical modelling for detecting concealed items on the human body in confined acoustic environments, supporting the development of non-invasive security screening technologies. Full article

This study presents a channel-free, micro-well–template-assisted magnetic particle trapping method for efficient single-particle isolation without the need for microfluidic channels. Dual-surface silicon micro-well arrays were fabricated using photolithography, PE-CVD, and DRIE processes, featuring hydrophilic well interiors and hydrophobic outer surfaces to enhance trapping performance. The proposed method combines magnet-assisted sedimentation with rotational sweeping of a glass slide placed above the micro-well array, enabling rapid and uniform particle confinement within a 250 × 250 well array. Experimental results showed that the trapping efficiency increased with the well width and depth, achieving over 93.8% within three trapping cycles for optimized structures. High single-particle occupancy was obtained for wells of comparable size to the particle diameter, while deeper wells enabled stable trapping with minimal loss. The entire trapping process was completed within five minutes per cycle, demonstrating a rapid, simple, and scalable approach applicable to digital immunoassay systems for ultrasensitive biomolecule detection. Full article

Melanoma cells in the brain may use similar mechanisms for adapting to injury and/or disease (that is, through continued reallocation of energy, matter, and information) as other cell types do to create an environment in which cancer cells can grow and sustain themselves within the confines of the brain. These adaptable mechanisms include the ability to reactivate dormant neural crest-derived migration and communication pathways. Unlike some other types of cancers that invade neural tissue as a simple invasion, melanomas are capable of achieving limited molecular, metabolic, and electrical similarity to the neural circuitry of the brain. Melanomas achieve this limited similarity through both vascular co-optation and mimicking synaptic functions, as well as through their engagement of redox-coupled metabolic pathways and feedback-regulated signal transduction pathways. The result is the creation of a metastable tumor–host system, where the relationship between tumor and host is defined by the interaction of stabilizing and destabilizing forces; forces that define the degree of coherence, vulnerability, and persistence of the tumor–host system. In this review, we integrate molecular, electrophysiological, and anatomical data to develop a single unifying hypothesis for the functional integration of melanoma cells into the neural tissue of the brain. Additionally, we describe how neural crest-based regulatory pathways are reactivated in the adult brain and how tumor–host coherence is developed as a function of the shared thermodynamic and informational constraints placed on both tumor and host. We also describe how our proposed conceptual model allows for the understanding of therapeutic interventions as selective disruptions of the neural, metabolic, and immunological couplings that support metastatic adaptation. Full article

Accurate, non-invasive glucose monitoring remains a major challenge in biomedical sensing. We present a high-sensitivity planar microwave biosensor that progresses from a 2-cell hexagonal array to an 8-cell hexagonal array, and finally to a 16-cell double-honeycomb (DHC-CSRR) architecture to enhance field confinement and resonance strength. Full-wave simulations using Debye-modeled glucose phantoms demonstrate that the optimized 16-cell array on a Rogers RO3210 substrate substantially increases the electric field intensity and transmission response |S₂₁| sensitivity compared with FR-4 and previous multi-CSRR designs. In vitro measurements using pharmacy-grade glucose solutions (5–25%) and saline mixtures with added glucose, delivered through an acrylic channel aligned to the sensing region, confirm the simulated trends. In vivo, vector network analyzer (VNA) tests were conducted on four human subjects (60–150 mg/dL), comparing single- and dual-finger placements. The FR-4 substrate (${\mathsf{\epsilon }}_{\mathrm{r}}$ = 4.4) provided higher frequency sensitivity (2.005 MHz/(mg/dL)), whereas the Rogers RO3210 substrate (${\mathsf{\epsilon }}_{\mathrm{r}}$ = 10.2) achieved greater amplitude sensitivity (9.35 × 10⁻² dB/(mg/dL)); dual-finger contact outperformed single-finger placement for both substrates. Repeated intra-day VNA measurements yielded narrow 95% confidence intervals on |S₂₁|, with an overall uncertainty of approximately ±0.5 dB across the tested glucose levels. Motivated by the larger |S₂₁| response on Rogers, we adopted amplitude resolution as the primary metric and built a compact prototype using the AD8302-EVALZ with a custom 3D-printed enclosure to enhance measurement precision. In a cohort of 31 participants, capillary blood glucose was obtained using a commercial glucometer, after which two fingers were placed on the sensing region; quadratic voltage-to-glucose calibration yielded R² = 0.980, root–mean–square error (RMSE) = 2.316 mg/dL, overall accuracy = 97.833%, and local sensitivity = 1.099 mg/dL per mV, with anthropometric variables (weight, height, age) showing no meaningful correlation. Clarke Error Grid Analysis placed 100% of paired measurements in Zone A, indicating clinically acceptable agreement with the reference meter. Benchmarking against commercial continuous glucose monitoring systems highlights substrate selection as a dominant lever for amplitude sensitivity and positions the proposed fully non-invasive, consumable-free architecture as a promising route toward portable RF-based glucose monitors, while underscoring the need for larger cohorts, implementation on flexible biocompatible substrates, and future regulatory pathways. Full article

A computational study is conducted on shock wave propagation and diffraction in an annular duct. The curved geometry and central obstruction of the annular configuration generate complex wave phenomena not typically observed in linear channels. The evolution of incident shock fronts, their interactions with the inner and outer walls, and the resulting diffraction patterns are analysed in detail. Particular focus is placed on the formation of reflected and transmitted waves, as well as the effects of curvature and channel dimensions on shock strength and propagation speed. High-resolution computational fluid dynamics (CFD) simulations are used to capture transient flow features, and results are validated against available experimental data. Simulations are performed across a range of annular geometries with varying radii of curvature and inlet Mach numbers. Simulations across a range of inlet Mach numbers (1.5–3.0) and radii of curvature show that increasing curvature intensifies shock focusing near the inner wall, raising local pressure peaks by up to 20%, while promoting faster attenuation of the transmitted wave downstream. At higher Mach numbers, the reflected shock transitions from regular to Mach reflection, producing triple-point structures. The comparison of shock structures across configurations shows good agreement with experimental observations. The findings enhance understanding of shock dynamics in non-standard geometries and have implications for the design of detonation engines, pulse detonation systems, and safety analyses in confined environments. Full article

This study presents a comprehensive overview of recent advancements in fire protection technologies for reinforced concrete (RC) structures, with a focus on sustainable and high-performance solutions. As climate change and urban densification continue to shape modern construction, the need for fire-resilient and environmentally responsible building systems has never been more urgent. This study examines traditional fire protection practices and contrasts them with emerging innovations. Emphasis is placed on their thermal performance, structural integrity post-exposure, and long-term durability. Case studies and laboratory findings highlight the effectiveness of these systems under standard and severe fire scenarios. This paper will present the results of a research study on the assessment of different fire protection systems for RC columns retrofitted with fiber-reinforced polymer (FRP) jacketing. To quantify how insulation can preserve confinement, three commercial fire protection schemes were tested on small-scale CFRP- and GFRP-confined concrete cylinders: (i) a thin high-temperature cloth + blanket (DYMAT™-RS/Dymatherm), (ii) an intumescent epoxy-based coating (DCF-D + FireFree 88), and (iii) cementitious mortar (Sikacrete™ 213F, 15 mm and 30 mm). Specimens were exposed to either 60 min of soaking at 200 °C and 400 °C or to a 30 min and 240 min ASTM E119 standard fire; thermocouples recorded interface temperatures and post-cooling uniaxial compression quantified residual capacity. All systems reduced FRP–interface temperatures by up to 150 °C and preserved 65–90% of the original confinement capacity under moderate fire conditions ($\le$400 °C and $\le$30 min ASTM E119) compared to 40–55% for unprotected controls under the same conditions. The results provide practical guidance on selecting insulation types and thicknesses for fire-resilient FRP retrofits. Full article

Building on Fox’s Scope Economy, Takahashi proposes an analysis of scope interactions in Japanese null argument constructions. Scope Economy prevents covert scope-shifting operations such as Quantifier Raising (QR) from being semantically vacuous. Equating scrambling of Japanese null arguments with QR, Takahashi argues that null arguments are also subject to Scope Economy and thus exhibit the same scope asymmetries observed in English VP-ellipsis. In this paper, we examine Korean null argument constructions, which exhibit the same patterns as their Japanese counterparts, and argue that Takahashi’s Scope Economy-based account falls short of capturing the full range of scope facts. Specifically, we show that scope asymmetries persist even when Scope Economy-violating scrambling takes place. This problem is not confined to null argument constructions but also arises in fragments. We argue that Schwarzschild’s GIVENness constraint, in conjunction with Parallelism, accounts for scope patterns in Korean null argument constructions, without recourse to Scope Economy. We further suggest that the proposed analysis can extend to English, thereby undermining the necessity of Scope Economy in both languages. Full article

Oropouche virus (OROV), an emerging arbovirus of the Peribunyaviridae family, is responsible for acute febrile illness and, in some cases, neurological or hemorrhagic complications. Although traditionally confined to tropical areas of Central and South America, the 2024–2025 epidemic has signaled a major shift in its geographic and clinical profile, with sustained transmission in the Caribbean, over 15,000 confirmed cases, and the first imported infections reported in Europe and the United States. New clinical observations include fatalities in previously healthy adults, suspected vertical transmission with adverse fetal outcomes, and potential sexual transmission. Despite entomological data indicating low competence of European mosquito species and the absence of the main vector Culicoides paraensis, the increasing frequency of imported cases underscores the need for continued vigilance. Diagnostic limitations and clinical overlap with other arboviruses further complicate early detection. This review summarizes current knowledge on OROV’s epidemiology, transmission dynamics, and clinical features, and highlights the urgent need for integrated surveillance, diagnostic readiness, and coordinated research efforts. Emphasis is placed on Europe’s preparedness strategies, with Italy’s Jubilee 2025 offering a real-world case study for managing arboviral threats during mass gatherings. Full article

Street art increasingly reshapes aesthetic hierarchies by introducing previously marginalised media into the public sphere. A compelling example is the artistic practice of the Polish artist NeSpoon (Elżbieta Dymna), whose work merges the visual language of traditional lace with the communicative strategies of contemporary urban art. Active since the late 2000s, NeSpoon combines stencils, ceramic lace imprints, and large-scale murals to translate the intimacy of handcraft into the visibility of public space. Her works function as both aesthetic interventions and acts of civic pedagogy. This study employs a qualitative visual research design combining multi-site digital inquiry, iconological and semiotic analysis, and mini focus group (N = 22). Three purposefully selected cases: Łódź, Belorado, and Fundão, were examined to capture the site-specific and cultural variability of lace murals across Europe. The analysis demonstrates that lace functions as an agent of cultural negotiation and a medium of heritage literacy, understood here as embodied and place-based learning. In Łódź, it monumentalises textile memory and women’s labour embedded in the city’s industrial palimpsest. In Belorado, micro-scale responsiveness operates, strengthening the local semiosphere. In Fundão, lace enters an intermedial dialogue with azulejos, negotiating the boundary between craft and art while expanding local visual grammars. The study introduces the conceptualisation of the monumentalisation of intimacy in public art and frames heritage literacy as an embodied, dialogic, and community-oriented educational practice. Its implications extend to feminist art history, place-based pedagogy, urban cultural policy, and the preventive conservation of murals. The research elucidates how domestic craft once confined to the private interior operates in public space as a medium of memory, care, and inclusive aesthetics. Full article

The present controlled experimental research addresses the effects of exposure to nature on workers’ well-being and job performance in a work-confined setting. Ten individuals working in an open-space office inside a Portuguese military bunker were exposed to simulated nature (audio sounds and/or video images of nature). Quantitative physiological (heart rate) and self-reported measures (perceived positive and negative emotions, environment restorativeness, and work performance) were taken. Results indicate that exposure to nature during working time in confined places, through simulating a window with a view of nature and/or by introducing sounds of nature, promotes physiological and emotional well-being at work (heart rate significantly decreases, positive emotions significantly increase, and negative emotions decrease), and significantly increases employees’ perception of workplace restorative qualities. The results on work performance were non-significant. The present findings contribute to the evidence of the restorative effects of nature exposure during work. The research bridges a gap by considering workplaces where real nature exposure is not feasible and examining the evidence on the beneficial biophilic interventions (the restorative effects of simulated nature) within confined environments. The strategy to use videos and audio of nature may improve the structural conditions of work, benefiting well-being in these types of work settings. Full article

The eco-toxicological impacts caused by organic pollutants in aquatic environments have emerged as a global concern in recent decades, resulting from the potential hazards they present to ecosystem integrity and human health. Decorating active components on mesoporous silica is considered a popular approach by which to obtain synergistic effects in persulfate activation for sustainable water decontamination. However, at present there has been no review focusing solely, specifically and comprehensively on this field. Therefore, this paper places an emphasis on the latest research progress on the synthesis and physicochemical properties of functionalized mesoporous silica materials as well as their catalytic performance. The preparation methods included co-condensation, impregnation, grinding–calcination, hydrothermal synthesis and chemical precipitation, and their synthesis parameters played a major role in the characterization of materials, thereby affecting pollutant elimination. Metal redox cycles, nonmetallic activation and confinement effects contributed to persulfate activation. Targeted pollutants were degraded via radical pathways, non-radical pathways, or a combination of the two. The effects and causes of operational conditions (catalyst and persulfate dosage, initial pollutant concentration, temperature, initial pH, co-existing anions, and natural organic matter) varied across the degradation systems, and they were categorized and summarized in detail. Furthermore, functionalized mesoporous silica presented excellent reusability, stability and applicability in practical application. Finally, current potential directions for further research and sustainable development in this field were also prospected. This critical analysis aims to fuel the evolution of functionalized mesoporous silica catalyst-driven persulfate system application in water treatment and to bridge prevailing knowledge gaps. Full article

Face swapping is commonly assumed to act locally on the face region, which motivates placing watermarks away from the face to preserve the integrity of the face. We demonstrate that this assumption is violated in practice. Using a region-aware protocol with tunable-strength visible and invisible watermarks and six face-swap families, we quantify both identity transfer and watermark retention on the VGGFace2 dataset. First, edits are non-local—generators alter background statistics and degrade watermarks even far from the face, as measured by background-only PSNR and Pearson correlation relative to a locality-preserving baseline. Second, dependencies between watermark strength, identity transfer, and retention are non-monotonic and architecture-dependent. Methods that better confine edits to the face—typically those employing segmentation-weighted objectives—preserve background signal more reliably than globally trained GAN pipelines. At comparable perceptual distortion, invisible marks tuned to the background retain higher correlation with the background than visible overlays. These findings indicate that classical robustness tests are insufficient alone—watermark evaluation should report region-wise metrics and be strength- and architecture-aware. Full article

The body–soul relationship serves as a crucial entry point for exploring the intersection of Plato’s dialogues with ancient Greek religious thought, particular Orphic doctrines. In critically inheriting and reconstructing core elements of Orphism, Plato initiates a paradigm shift from mythos to logos—transitioning from mythic narrative to philosophical reasoning. In the context of Greek religious history, Orphism was the first to articulate a dualism between soul and body, depicting the body as a “prison” that confines the divine soul. While Plato frequently references this framework in his dialogues, he simultaneously exposes its inherent contradictions. By distinguishing between the soul’s pure and embodied states, Plato rejects the Orphic notion of bodily impurity. Instead, he reinterprets the body’s negativity not as religious “original sin,” but as the interference of sensory experience and desire in rational life. He affirms that the soul maintains its rational autonomy even in embodiment, with desire and thymos (spirit) emerging naturally from this process, thereby disclosing the soul’s intrinsic structure. In place of a strict dualism, Plato introduces a tripartite model of the soul, positioning thymos as the mediating force between reason and desire. The ambiguity of thymos functions as a self-regulating mechanism that enables the soul to maintain dynamic balance. In this moral psychology, virtue is no longer defined as the soul’s rejection of the body, but as the soul’s harmonious order and natural growth within it. Plato thus adopts a complex and cautious stance toward Orphism, ultimately transcending its passive ethical outlook and transforming a mythical doctrine into a rational philosophical system. Full article

In many engineering applications, multi-objective optimization problems can be reformulated as single-objective problems with multiple constraints to improve computational efficiency. This paper discusses the characteristics and challenges of RF accelerating structure optimizations and proposes an enhanced single-objective optimization strategy based on progressive exploration method to find the global optimal solution within a large solution space characterized by a continuous and confined distribution of feasible solutions. It begins from an arbitrary feasible solution and progressively slides and expands the solution space fragment along the distribution path of feasible solutions to rapidly explore the entire space. By incorporating a re-initialization mechanism to enhance swarm diversity and introducing penalty factors in place of constraints to increase the number of feasible solutions, the algorithm significantly improves its ability to escape local optima traps. The proposed algorithm is applied to optimize a DAA structure, yielding satisfactory results and convergence speed. These results highlight the method’s effectiveness and its potential applicability to other complex constrained optimization problems. Full article

The welfare of decapod crustaceans held in captivity, whether in aquariums, holding facilities, seafood restaurants, supermarkets, or fishmongers, is attracting growing attention and concern. This review focuses on three species that are commonly found in European commercial environments: the European spiny lobster (Palinurus elephas), the European lobster (Homarus gammarus), and the American lobster (Homarus americanus). We examine the biology and behavioural ecology of these decapods, emphasising their natural habits and environmental requirements. Based on current scientific knowledge, we propose conditions for their confinement that better align with their biological and behavioural needs. These crustaceans are commonly subjected to stressful captive environments characterised by overcrowding, claw immobilisation through banding, an absence of shelter or hiding spaces, and continuous exposure to direct lighting. Such practices contrast starkly with the animals’ innate behaviours and natural habitats, likely compromising their physical health and psychological welfare. It is thereby recommended that spiny lobsters and lobsters be kept separated and stocked at an appropriate density, that each animal should be provided with a shelter and have enough space to turn around, that true lobsters should never have their claws tied, that no direct light should be placed above the aquaria, and that water quality should be routinely monitored. By exploring the welfare challenges associated with confining these species, this review aims to promote a more ethical and humane approach to their care in commercial settings, and to encourage practices that enhance their quality of life in captivity. Full article