Search Results (539)

This cross-sectional study aims to identify clusters of internalizing and externalizing traits during adolescence using a bottom-up approach. The second aim is to investigate whether the different clusters differ by environmental risk factors and specific epigenetic profiles. A total of 205 adolescents, who had been referred for psychopathology in childhood, were recruited. Behavioral problems were assessed using the Child Behavior Checklist/6–18 (CBCL). Different clusters of psychopathological profiles were analyzed using a Finite mixture model. Differences in environmental risk factors and epigenetic profiles were tested with χ²-tests and Bonferroni-corrected t-tests. Two clusters were identified: a LOW cluster (51% of the sample), characterized by the presence of subclinical mean scores in both internalizing and externalizing problems, and a HIGH cluster (49% of the sample), characterized by high mean scores in both domains. The HIGH cluster had a significantly greater number of perinatal complications and changes in methylation of specific CpG sites of Brain-derived neurotrophic factor, Insulin-like growth factor-2, and Oxytocin receptor, whereas no difference was found for FK506-binding protein 5. Our results confirm the existence of a strong association between early adverse events, DNA methylation, and the presence of behavioral problems and psychopathological traits in adolescence. Full article

While gestational Bisphenol A (BPA) exposure has been associated with autism, limited work has focused on dietary sources. Here, we sought to develop a summary metric to capture dietary exposure specifically and test its associations with measured levels, as well as child traits related to autism. Participants (n = 116) were from the Early Autism Risk Longitudinal Investigation (EARLI) Study, which recruited pregnant women who previously had a child diagnosed with autism. Maternal concentrations of BPA were quantified in urine, and dietary sources of BPA were ascertained via food frequency questionnaires during gestation. A novel BPA “dietary burden score” was developed based on reported intake of foods known to contribute to BPA exposure (i.e., canned foods) from a Dietary History Questionnaire modified for pregnancy. Child autism-related traits were assessed via the Social Responsiveness Scale (SRS-2). We examined associations between BPA biomarkers, dietary burden scores, and child SRS scores. Dietary burden scores were weakly correlated with urinary BPA concentrations (R = 0.19, p = 0.05) but were not associated with child SRS scores. Our work suggests that more detailed dietary assessments may be needed to fully capture diet-based BPA exposures and address diet as a modifiable source of chemical exposure to reduce associated health impacts of BPA. Full article

Background/Objectives: Childhood stunting remains a critical public health issue in low- and middle-income countries. Despite Malaysia’s economic growth, there is limited large-scale evidence on the determinants of stunting among children from infancy to primary school age. This cross-sectional study, part of South East Asian Nutrition Surveys II (SEANUTS II), aimed to determine sociodemographic and environmental risk factors for stunting among 2989 children aged 0.5–12 years. Methods: Children were recruited from four regions in Peninsular Malaysia (Central, East Coast, 2022–2030Northern, Southern). Standing height or recumbent length was measured, and stunting was classified based on WHO criteria (height-for-age Z-score below −2 standard deviations). Parents reported information on socioeconomic status, sanitation facilities, and hygiene practices. Multivariate binary logistic regression was used to determine the determinants of stunting. Results: Stunting prevalence was 8.9%, with infants (aOR = 2.92, 95%CI:1.14–7.52) and young children (aOR = 2.92, 95%CI:1.80–4.76) having higher odds than school-aged children. Key biological predictors included low birth weight (aOR = 2.41; 95%CI:1.40–4.13) and maternal height <150 cm (aOR = 2.24; 95%CI:1.36–3.70). Chinese (aOR = 0.56; 95%CI:0.35–0.88) and Indian children (aOR = 0.16; 95%CI:0.05–0.52) had a lower risk of stunting compared to Malays. Conclusions: This study highlights the ongoing challenge of childhood stunting in Malaysia, with age, birth weight, ethnicity, and maternal height identified as key determinants. These findings call for early identification of at-risk households and targeted support, especially through education and financial aid to foster healthy child growth. Full article

Many patients with psychosis have dependent children. Being a parent is an important and valued role for people with psychosis. However, the experience of psychosis can disrupt parent–child interactions, which can negatively affect both parents and children. Despite this understanding, there remains a lack of diagnosis-specific parenting interventions for parents with lived experience of psychosis. An eight-week digital mentalization-based parenting group intervention (Me, My Child, and Us) was piloted to evaluate its acceptability, feasibility, and impact on self-reported parenting satisfaction, parental relationship, and overall wellbeing. The study used a within-participant non-controlled pre–post design using mixed quantitative and qualitative methodology. Thirteen parents with dependent children were recruited and two eight-week groups were run. Eleven parents completed the intervention, the pre- and post-group measures, and provided qualitative feedback on their experience of the intervention. On average, parents attended 75% of sessions. Parents reported high satisfaction with the content and structure of the group. Scores on pre- and post- group measures suggest improvements in self-reported parental wellbeing, parental relationship, parenting stress levels, parenting satisfaction and efficacy, as well as mentalizing capacity. The Me, My Child, and Us parenting group is feasible to deliver and acceptable for parents with lived experience of psychosis. The preliminary self-report data indicate a controlled evaluation of the intervention as the next step. Full article

Background: Childhood obesity disproportionately affects Hispanic families in the U.S. Although parenting practices and interventions appear to be viable approaches to lower the risk of childhood obesity, there is limited information on which parenting practices would be relevant and culturally appropriate for Hispanic families. This study aimed to document the health-related factors that impact Hispanic parenting practices to inform evidence-based parenting interventions to improve child health outcomes and reduce the risk of childhood obesity. Methods: We conducted cross-sectional, formative research guided by the COREQ checklist. Hispanic parents of elementary school-aged children were recruited using purposive and snowball sampling. Eligible parents completed a brief sociodemographic survey, the Comprehensive Feeding Practices Questionnaire (CFPQ), and an individual semi-structured interview. Quantitative data were analyzed using descriptive statistics, and qualitative data were analyzed using a coding-based thematic approach. Results: Seventeen parents (88.2% female) participated in the study, and the majority reported Spanish as their preferred language (70.6%). According to parent-reported data, the children’s (52.9% female) mean age was 8.4 ± 1.5 years, and over half were classified as having overweight or obesity. The CFPQ analysis indicated that parents scored highest on subscales related to encouraging healthy eating and eating variety, a finding that was reinforced by interview data. Qualitative analysis identified four key themes: 1. parenting roles, routines, and strategies for promoting culturally appropriate and healthy meals; 2. beliefs of children’s health and weight; 3. beliefs on physical activity and screen time; and 4. environmental and social factors affecting access to healthy food and physical activity. Conclusions: Both quantitative and qualitative results emphasize that parents engage in healthy eating guidance and eating variety and are aware of the factors that impact parenting practices and their children’s health. To improve child health outcomes and reduce the risk of childhood obesity among Hispanic families, parenting interventions need to be culturally responsive and address the factors that influence parenting practices. The findings from this study highlight four key areas to prioritize when designing or adapting parenting interventions to lower the risk of childhood obesity among Hispanic families. Full article

Background: Vietnam is experiencing a significant “double burden” of malnutrition, characterized by the persistent challenge of undernutrition, particularly stunting in ethnic minority and mountainous regions, alongside a rising prevalence of overweight and obesity. Understanding dual nutritional status and its related factors in adolescents from these vulnerable areas is crucial for effective intervention. Objective: The current study explored the nutritional status of ethnic minority secondary school students in some mountainous provinces in the northwest of Vietnam and identified some related factors. Methods: We conducted a cross-sectional study over six months (June–December 2023), involving 1847 ethnic minority high school students from Son La and Dien Bien provinces, recruited through convenience sampling in primary healthcare settings. Nutritional status was determined using WHO 2006 Child Growth Standards, specifically height-for-age Z-scores (HAZ) and body mass index (BMI)-for-age Z-scores (BAZ). A 4-point scale assessed nutritional practices, including food consumption frequency and eating habits. Results: This study identified a stunting (HAZ < −2 SD) prevalence of 16.7% and wasting (BAZ < −2 SD) of 5.6%; overweight/obesity (BAZ > +1 SD) prevalence was 8.2%. Key factors related to stunting were being male, having more siblings, poor/near-poor household economic status, low maternal education level, and frequent occurrences of gastrointestinal and respiratory diseases. A higher risk of overweight/obesity was associated with consuming more than three meals daily, nocturnal snacking, frequent intake of fried foods, insufficient consumption of vegetables and fruits, and inadequate daily physical activity. Conclusions: Our study shows a comprehensive picture of malnutrition among children in ethnic minority areas. Essential nutritional intervention programs, projects, and models are a top priority to reduce the disease burden for children’s bright future and to enhance socio-economic development in the mountainous regions of Vietnam. Full article

Background/objectives: This study addresses two questions: what body sizes/shapes do participants believe correspond to the boundaries of the National Child Measurement Programme (NCMP) weight categories for children aged 4–5 and 10–11 years old, and are these judgements altered by using terminology encouraging positive action by parents? Methods: The study used photorealistic computer-generated stimuli based on 388 3D scans of children in a method of adjustment task. We first asked participants to estimate the boundaries between weight status categories as described by the NCMP. To test validity, we asked a second set of participants to estimate the body that represented exemplars of each weight category (the exemplars should fall between the boundary estimates). We then recruited a third set of participants to determine whether substituting positive action terminology for the weight status definitions altered the boundary positions. Results: First, validity was confirmed. Second, we found a compressed response range (lower weights overestimated and higher weights underestimated) for the positioning of both categorical boundaries and exemplars. Finally, the use of alternative weight status terminology resulted in an upward shift in the position of all boundaries in the BMI spectrum but failed to remove the compressive stimulus response effect. Discussion: There is a disconnect between the child size that people perceive to correspond to the different weight categories and the size criteria used by health professionals, and it is likely that this gap can only be bridged by training to recognise the medically based categories. Full article

Background/Objectives: School bullying is a significant issue that negatively impacts children’s well-being, emphasizing the need to identify family-related factors contributing to bullying victimization. This study explored the potential link between parental marital quality and school bullying victimization by employing a moderated mediation model. Methods: Parent–child attachment, measured separately as father–child and mother–child attachment, was tested as a mediator, with child gender included as a moderator. Data were collected from both children and their mothers, comprising 358 mother–child pairs recruited from three primary schools in suburban Beijing, China. Results: Results revealed that greater parental marital quality was associated with a lower risk of bullying victimization, with father–child attachment mediating this relationship. Furthermore, child gender moderated the mediating effect of father–child attachment, such that the indirect pathway from parental marital quality to bullying victimization through father–child attachment was statistically significant for girls but not for boys. Conclusions: These findings highlight the importance of father–child attachment in preventing bullying victimization and suggest that gender-sensitive implications may be necessary. Full article

Objective: To characterize the nutritional status of the child population and to identify the most relevant determinants that could influence the early development of obesity and overweight. Methods: A descriptive cross-sectional study was conducted, recruiting a representative sample (698 schoolchildren, aged between 5 and 14, and obtaining information from a total of 414 households), using of anthropometric methods for nutritional assessment, the FIES scale, the KidMed index, and questions from the COSI survey. Results: Overall, 27% of the sample had healthy weight, 22.6% were overweight, and 18.1% were obese, with a higher prevalence among boys, and 86.7% of the sample did not adhere to dietary habits consistent with the Mediterranean diet. Food insecurity was present in 45.6% of the sample. A mean weight increase of 2.6 kg (95% CI: 1.0–4.3) was observed for each additional kilogram the child weighed at birth, 2.0 kg (95% CI: −0.2–4.3) in children living in households with some difficulty making ends meet, and 4.8 kg (95% CI: 1.3–8.3) in those from households reporting that they do not or barely manage to make ends meet. A statistically significant association was found with gross annual household income, with children from households earning less than EUR 12,000 having a 3.6 times higher risk of overweight/obesity compared to those from households earning more than EUR 36,000. Conclusions: The prevalence of obesity and overweight is considerably higher in low-income families and is significantly associated with family economic capacity. Continued epidemiological surveillance of these conditions and their relationship with social determinants is necessary. Full article

Background: Children, including the estimated 7% with food allergy, spend most of their waking hours in school. Variations in school-based food allergy (FA) practices exist. We aimed to examine differences in FA management practices across schools in Canada and the United States (US). Methods: Parents of children with Immunoglobulin E (IgE)-mediated FA were recruited through social media to complete a survey evaluating the schools’ stock epinephrine, epinephrine storage locations, school type, and location. Data were described, analyzed using logistic and linear regressions, and then reported as odds ratios (ORs) and standardized coefficients (b), respectively, with corresponding 95% confidence intervals (95%CIs) and p < 0.05. This study was approved by the University of Manitoba Health Research Ethics Board. Results: Overall, 177 participants (14% [26/177] Canada, 86% [151/177] US) were included. Children were, on average, 4.92 ± 3.12 years and were commonly but not mutually exclusively allergic to tree nuts (50% Canada; 40% US) and peanuts (33% Canada; 29% US). Compared to US parents, Canadian parents were more likely to report epinephrine self-carriage by their children (OR = 4.58; 95%CI = 1.67–12.59). Parents with children age > 5 years were more likely to report epinephrine self-carriage by their children (OR = 3.70; 95%CI = 1.38–9.93) but less likely to report that their children’s school had an allergen-friendly zone (OR = 0.25; 95%CI = 0.06–0.99). Compared to US parents, Canadian parents were more likely to report their child’s school had anaphylaxis management policies (OR = 8.98; 95%CI = 1.11–72.42). Conclusions: Significant in-school FA management differences exist between countries. These findings stress the need for consistent policies and practices to ensure effective care. Full article

Background/Objectives: Despite the growing recognition of cognitive disengagement syndrome (CDS), previously termed sluggish cognitive tempo, as a distinct dimension of psychopathology, the neural correlates of CDS remain largely unknown. We investigated the neural correlates of CDS in children using whole-head magnetoencephalography (MEG). Methods: A community-based sample of children (N = 43, ages 8–12 years) was recruited and completed self-report ratings of CDS. MEG was recorded while the children completed an adapted version of the attention network test (ANT). Results: The results indicated that higher levels of self-reported CDS symptoms were associated with larger changes in the root-mean square (ΔRMS) (incongruent—congruent trials) in M2 and M3, suggesting children with higher levels of CDS symptoms might require greater mental effort to overcome distractors during incongruent trials. The source localization analysis initially revealed a negative correlation between child self-reported CDS symptoms and ΔM2 power (incongruent—congruent trials) in the medial prefrontal cortex (mPFC), suggesting insufficient power allocation in a region critical for attentional processing. However, this association was no longer significant after controlling for ADHD status. No significant correlation was found between self-reported CDS symptoms and alerting or orienting. Conclusions: These findings provide initial evidence of the disrupted attentional processing associated with CDS in children. Further replication and extension with larger samples are warranted. Full article

Background/Objectives: Findings from the Learning Early About Peanut trial prompted a shift in clinical practice guidelines to support the early and continuous introduction of allergenic foods to reduce the risk of food allergy. Our study aimed to describe the reasoning behind parents’ decisions on the introduction of first foods to their infants and the age at which parents first introduced common allergens. Methods: Parents of a child aged <18 years old with ≥1 food allergy, who lived in either Canada or the United States, were recruited via social media between March 2021 and February 2022 to participate in an online, anonymous survey. Data were analyzed descriptively and using binary logistic regression. Results: A total of 42 parents completed the survey, the majority being mothers (40/42; 95.2%). Children were, on average, 6.9 ± 0.7 years old. In total, 47.6% of parents introduced first foods between ages 4–5 months, whereas 52.4% introduced first foods at 6 months or older. Cereals were the most frequently introduced first food (54.8%; 23/42). Most parents (71.9%) selected first foods to introduce based on guidance from healthcare providers. Conclusions: For many parents, guidance from healthcare providers is the most influential factor in determining when and what to introduce as first foods to their infant. Although the paradigm shift in infant feeding practices has been well accepted by healthcare providers, this information has not been adequately translated to the general population. This emphasizes the need for healthcare providers to educate and reinforce the importance of early introduction to reduce the risk of food allergy. Full article

The article explores the concept of family language policy in relation to heritage languages and child agency in the context of Latvian as a heritage language. Its aim is to find out what role Latvian may have in relation to other languages within the core families in the diaspora, as well as in communication with their extended families in Latvia. For this, we investigate which language beliefs and attitudes underlie those language practices and examine children’s engagement in family language management. Our research is based on 20 in-depth interviews collected in 2023. Respondents were recruited through the distance online learning program “Latvian as a foreign language teacher” created for the Latvian diaspora and through Saturday (community) schools. The main research questions are as follows: What role does Latvian have in relation to other languages in Latvian diasporic families, and how do language practices reflect beliefs and attitudes of the parents? Which languages and which communication channels are used by diasporic families in communication with their (extended) families in Latvia? What impact do children have on family language policies? Our data show a huge diversity in family language practices, switching between two and more languages depending on communicative situations, the age of children, their language proficiency, and the communication channels. Family members flexibly use their languages to participate in family life and to achieve interactional goals, not always focusing just on particular language use. Heritage language transmission correlates with family language planning and consequent language use. On the other hand, language is tightly tied to the relationships and emotions of family members. Full article

Background/Objectives: The number of children with overweight and obesity is gradually increasing worldwide. This is an emergent public health problem as overweight and obesity persist through the next stages of human life, being associated with high risk of morbidity and mortality. In this respect, the purpose of the current cross-sectional survey is to explore whether the overweight/obesity of children aged 6–9 years may be related to the risk of developing perceived stress and poor sleep quality symptoms. Methods: This study recruited 4350 primary school children from diverse Greek rural and urban regions. The mothers of the enrolled children completed relevant questionnaires on children and maternal sociodemographics, anthropometric parameters, perinatal outcomes, breastfeeding practices, and lifestyle factors. The enrolled mothers also completed the Perceived Stress Scale (PSS) and the Pittsburgh Sleep Quality Index (PSQI) to evaluate the perceived stress and sleep quality of their matched children, respectively. Results: Our analysis reveals independently significant associations between diverse factors and children’s overweight/obesity such as child’s gender, family economic status, maternal gestational weight gain, childbirth weight, kind of delivery, exclusive breastfeeding, and children physical activity. Childhood overweight and obesity were independently associated with a more than three-fold higher risk of perceived stress and a more than two-fold higher likelihood of poor sleep quality after adjustment for multiple confounding factors. Conclusions: Obesity and overweight are related to enhanced risk of perceived stress and poor sleep quality in children aged 6–9 years. Public policies and dietary counseling interventions should be applied to inform new mothers about the harmful effects of childhood overweight/obesity and to direct them to adopt healthy dietary practices for their children. Full article

Background/objectives: Influenza vaccines are recommended and free in Australia for children aged <5 years, but uptake remains low at 25.8% compared to the targets of 40% and 50%. National data on barriers hindering paediatric influenza vaccination can inform strategies to improve uptake. The aim of this study was to measure barriers to influenza vaccination in Australian children aged <5 years. Methods: A national, cross-sectional survey of parents of children aged <5 years was conducted in March/April 2024. Parents were recruited using an online panel and asked about their intention to get an influenza vaccine for their youngest child in the upcoming influenza season. An adapted version of the validated Vaccine Barriers Assessment Tool measured 14 influenza vaccination barriers. Analysis assessed the prevalence of barriers and differences between parents intending to and those unsure or not intending to vaccinate by calculating the prevalence difference and 95% confidence interval. Results: A total of 2000 parents were recruited nationally. The most common barrier was parents feeling distressed when thinking about vaccinating their child against influenza (66.1% of intending parents, 65.6% of unsure/not intending parents). The barrier with the largest difference between intending and not intending/unsure parents was not prioritising their child’s influenza vaccination (47.2% vs. 6.1%, PD = 41.1 ppts, 95% CI: 35.9%, 46.3%). Other barriers with large differences were parents not feeling guilty if their unvaccinated child got influenza (41.5% vs. 7.5%, PD = 34.0 ppts, 95% CI: 28.8%, 39.1%) and parents not believing that influenza vaccines are effective (31.3% vs. 3.0%, PD = 28.2 ppts, 95% CI: 23.6%, 32.9%). Conclusions: Parents should be encouraged and supported to prioritise influenza vaccination alongside routine childhood vaccines in campaigns that emphasise disease risk and the importance, safety and effectiveness of influenza vaccination, and by optimising access to influenza vaccination. We recommend conducting similar surveys regularly to monitor trends in parental barriers to childhood influenza vaccination. Full article