Search Results (420)

Eutrophication has intensified in lacustrine systems across the American continent, which has been primarily driven by human activities such as intensive agriculture, wastewater discharge, and land-use change. This phenomenon adversely affects water quality, biodiversity, and ecosystem functioning. However, studies addressing the historical evolution of trophic states in lakes and reservoirs remain limited—particularly in tropical and subtropical regions. In this context, sedimentary records serve as invaluable archives for reconstructing the environmental history of water bodies. Paleolimnological approaches enable the development of robust chronologies to further analyze physical, geochemical, and biological proxies to infer long-term changes in primary productivity and trophic status. This review synthesizes the main methodologies used in paleolimnological research focused on trophic state reconstruction with particular attention to the utility of proxies such as fossil pigments, diatoms, chironomids, and elemental geochemistry. It further underscores the need to broaden spatial research coverage, fostering interdisciplinary integration and the use of emerging tools such as sedimentary DNA among others. High-resolution temporal records are critical for disentangling natural variability from anthropogenically induced changes, providing essential evidence to inform science-based lake management and restoration strategies under anthropogenic and climate pressures. Full article

Emerging evidence highlights the role of the tumor microbiome, including Fusobacterium nucleatum (Fn), in a wide range of gastrointestinal cancers. Fn purportedly contributes to tumorigenesis by activating oncogenic pathways and modulating immune responses. Although the prevalence and impact of Fn has been extensively studied in colorectal cancer, no previous systematic or in situ studies have been performed in appendiceal cancer (AC). The aim of this study was to evaluate the prevalence and association of Fn density in AC with clinical factors and oncologic outcomes. Archival tissue from 54 patients with AC was assessed for Fn density using RNA in situ hybridization. Clinicopathological variables were obtained for each case through electronic medical record review, and the immune microenvironment was characterized in each case using immunohistochemistry to quantify CD3+ and CD8+ T lymphocytes and M1-/M2-like tumor-associated macrophages. In AC, Fn density was associated with patient age, tumor grade, and histologic subtype. Fn was negatively associated with CD3+ and CD8+ T lymphocytes and positively associated with M2-like TAMs in low-grade AC. Interestingly, tumor Fn content was associated with better overall and progression-free survival, even when controlling for tumor grade. In this exploratory study, we found that Fn is prevalent in AC. Fn is associated with a number of clinical, pathologic, immunologic, and prognostic variables in AC that are distinct from the corresponding observed associations in colorectal cancer. Further research is warranted to validate these findings and explore the mechanistic contributions of Fn to AC pathogenesis or immune response. Full article

Some of the most intense thunderstorms and extreme weather events on Earth occur in the Hindu Kush Himalaya (HKH) region of Southern Asia. The need to provide end users, stakeholders, and decision makers with accurate forecasts and alerts of extreme weather is critical. To that end, a cutting edge weather modeling framework coined the High Impact Weather Assessment Toolkit (HIWAT) was created through the National Aeronautics and Space Administration (NASA) SERVIR Applied Sciences Team (AST) effort, which consists of a suite of varied numerical weather prediction (NWP) model runs to provide probabilities of straight-line damaging winds, hail, frequent lightning, and intense rainfall as part of a daily 54 h forecast tool. The HIWAT system was first deployed in 2018, and the recently released model archive hosted by the Global Hydrometeorology Resource Center (GHRC) Distributed Active Archive Center (DAAC) provides daily model outputs for the years of 2018–2022. With a nested modeling domain covering Nepal, Bangladesh, Bhutan, and Northeast India, the HIWAT archive spans the critical pre-monsoon and monsoon months of March–October when severe weather and flooding are most frequent. As part of NASA’s Transformation To Open Science (TOPS), this data archive is freely available to practitioners and researchers. Full article

Background: Primary aldosteronism is characterized by elevated aldosterone levels, leading to adverse effects such as hypertension, hypokalaemia and increased risk for cardiovascular and cerebrovascular events. Aldosterone impacts the central nervous system by promoting vascular remodelling and oxidative stress, potentially impairing cognitive function. The presence of mineralocorticoid receptors in the hippocampus, a key region for cognition, further suggest a link between primary aldosteronism and cognitive dysfunction. This study aims to further explore the association between hyperaldosteronism and cognitive impairment. Methods: In this pilot study we examined 15 individuals with primary aldosteronism and arterial hypertension alongside 15 age- and sex-matched controls with essential hypertension, all free of previous cerebrovascular events. Clinical and archival laboratory data were obtained. Cognitive function was assessed using the Mini-Mental State Examination and Montreal Cognitive Assessment. Results: Participants with primary aldosteronism had higher blood pressure values, longer duration of hypertension, lower serum potassium levels and higher 24 h urine albumin excretion rate compared to controls. Comorbidities, other characteristics and laboratory values were comparable across the two groups. No differences were observed in Mini-Mental State Examination scores, but Montreal Cognitive Assessment scores were significantly lower in the primary aldosteronism group (25.1 ± 2.2 vs. 27.1 ± 2.2, p = 0.021). Trends of poorer performance in language and attention/executive function domains were noted in primary aldosteronism individuals, as well as a higher number of pathological Montreal Cognitive Assessment scores (7 vs. 3). No significant correlations were found between cognitive test results and aldosterone concentrations or blood pressure in primary aldosteronism group. However, importantly, multiple regression analysis showed that aldosterone levels have a significant impact on Montreal Cognitive Assessment test, independent of blood pressure or duration of hypertension. Conclusions: This study supports an association between hyperaldosteronism and cognitive dysfunction, underscoring the need for more active detection and targeted treatment of primary aldosteronism. These findings warrant further research in larger cohorts to better elucidate this relationship. Full article

This article traces the development of video activism in Turkey over the past two decades, focusing on its transformation during and after the 2013 Gezi Park protests. Situating video activism as a form of radical media, it examines how activists have used digital recording technologies to document protests, amplify marginalized voices, and contest dominant narratives. Drawing on interviews with members of eight activist collectives, the article maps the evolving practices, ethics, and internal dynamics of video activism, paying close attention to tensions between visibility and security and between participation and professionalism. The Gezi protests marked a turning point, expanding video activism into a decentralized, diverse, and participatory field. In the aftermath, while collective structures weakened due to increasing repression and shrinking protest spaces, the use of video as a tool for testimony, expression, and archiving has continued to evolve. New actors, forms, and platforms have emerged, transforming video activism from a specialized practice into a broader, more diffuse form of engagement. This article argues that video activism remains a significant mode of mediated resistance, reflecting the challenges and the evolving potential of visual intervention in an ever-changing political landscape. Full article

From an outside perspective, it is not clear whether the Catholic Church is an active digital entity, or at least, it is not perceived as such. This paper analyses this issue. The methodology involved the monitoring of ecclesiastical Internet activity, SWOT analysis and in-depth interviews (seven) with clergy and technological suppliers of the Church in both Spain and Latin America. Results: Catholic Church digitalisation is spontaneous, as a reflection of society at large, and is heterogeneous due to its decentralised management. There is more inner acceptance of digital mediatisation for proclamation or support in faith (i.e., apps for praying) and less acceptance for the digitalised practice of rites (digital mediation in the celebration of sacraments is an open debate); however, the presence of ICTs in sacred places is increasing (i.e., liturgical books on screen). The evangelisation of the digital continent is an objective of the Church, whereby clergy influencers are the most striking but less solid case. There is almost full digital implementation at the functional level (i.e., digitised accounting and archives). Only charitable action with vulnerable groups remains analogue. Polarisation is also present, as ultra-Catholic groups are over-represented on the Internet. Conclusion: The Catholic Church is integrated in the Information and Digital Age but is also concerned with spiritual impoverishment, as online fragmentation does not feed real humanitarian communities. Full article

Ancient paintings are an intangible window to the economy, politics, and customs of the past. Their characteristics have evolved or were made obsolete, with only limited contemporary connections remaining. This research aims to preserve and to interact with characters in 2D paintings to evolve their cultural identity through combining AI and AR. The scope of this research covers traditional Chinese paintings archived by the National Palace Museum in digital collections, mainly “New Year’s Market in a Time of Peace”. About 25 characters were used for training and 3D reconstruction in RODIN^®. The models were converted into Augment^® and Sketchfab^® platforms as reactivated AR characters to interact with new urban fabrics and landscapes. Stable Diffusion^® and RODIN^® were successfully integrated to perform image training and reconstruct 3D AR models of various styles. As a result, interactions were conducted in two ways: in a mixed context with mixed characters in a painting and in a familiar context in the real world with mixed characters. It was found that AR facilitated the interpretation of how the old urban fabric was arranged. Using AI and AR is a current issue. Combining AI and AR can activate ubiquitous preservation to perform recursive processing from diffused images in order to reconstruct 3D models. This activated heritage preservation method is a reasonable alternative to redefining intangible subjects with a new and evolved contemporary cultural identity. Full article

As a mammal with unique ecological habits, the Chinese pangolin, Manis pentadactyla, exhibits nocturnal behavior and has a hidden, cave-dwelling lifestyle. Severe habitat degradation and fragmentation have led to a rapid decline in its wild population. Moreover, the immature state of artificial breeding technology restricts the availability of research samples, particularly with regard to behavioral and ecological data. This makes it extremely difficult to continuously monitor the pangolin’s ecological habits and population dynamics for a long time. The comprehensive research archive is yet to be established, greatly limiting the in-depth understanding of this species’ ecological behavior. To mitigate this data shortage, this study installed GPS positioning and accelerometer technology devices on five Chinese pangolins that were rescued from Zhejiang and released into the wild. Activity rhythms and home ranges were then analyzed based on the collected data. The results showed that all the five released Chinese pangolins were active in the wild and survived throughout the tracking period (21–72 days). The pangolins were mainly active at night, with activity starting after 18:00 and being mainly concentrated between 22:00 and 4:00. The home range of the Chinese pangolins based on MCP was 777.41 ± 426.26 hm², and the core range based on KDE was 596.21 ± 265.58 hm² (50% KDE). This result confirms that high-frequency GPS positioning combined with accelerometer data can effectively determine the home range sizes, habitat utilization, and fine-scale activity rhythms of wild-released pangolins. Full article

Archives have the potential to contribute to national development by preserving historical records and providing access to information. However, their impact is constrained by ineffective outreach strategies, insufficient institutional investment, and low public visibility. Public programming has been used as a strategic approach to bridge the gap between archival institutions and their user communities through engagement initiatives. Therefore, the objective of this study was to systematically review and analyse the diverse public programming activities undertaken by archival institutions globally and to identify the resultant outcomes of these engagements. To achieve this, the study employed a systematic literature review methodology, examining scholarly publications to synthesise existing evidence on public engagement in archives, thereby providing a comprehensive overview of current practices and their demonstrated impacts. The systematic review was conducted in accordance with PRISMA guidelines, utilising a two-stage selection process involving a search of six databases and four specialised journals. This search yielded 39 publications that met the inclusion criteria. Methodological rigour was evaluated using the CASP checklist. The results from the study indicated that exhibitions, educational programmes, community outreach, and digital initiatives were the most common public programming strategies. These activities enhance public awareness, increase accessibility, and foster community engagement. Despite the availability of various public programming activities, challenges such as inadequate funding, lack of digital infrastructure, and bureaucratic constraints hinder their effectiveness. The need for structured outreach strategies, institutional support, and the integration of emerging technologies to optimise public programming in archives is emphasised. The findings contribute to improving archival accessibility and user engagement in a rapidly evolving digital landscape. Full article

The Myanmar government aims to eliminate malaria by 2030, but comprehensive summaries of its malaria control efforts are scarce. To support this goal, a literature review and long-term document preservation are essential. This study collected academic papers, master’s and doctoral theses, and policy documents on malaria control in Myanmar and its surrounding regions, published between 1950 and 2016 through Official Development Assistance. The documents were sourced from online databases, medical universities, and research institutions in Yangon. They were categorized by region and WHO-defined malaria control activity areas and archived digitally at the Ministry of Health. A total of 1107 relevant papers were identified, with 818 collected. Epidemiology-related studies accounted for 40%, followed by drug resistance, surveillance, and treatment. Recent years have seen a rise in genetic and molecular epidemiology research. Full-text analysis revealed significant malaria research in border regions, particularly near the borders of Thailand and China. This study highlights the progress and historical trends in Myanmar’s efforts to control malaria. The archive created will be a valuable resource for future policy planning and implementation efforts aimed at achieving malaria elimination. Full article

The forest ecosystems of large Mediterranean islands are critical hubs of evolutionary diversity with unique floristic composition and distinctive vegetation patterns reflecting long-term population dynamics and ecological legacies. Mediterranean islands provide invaluable natural archives, preserving crucial insights into the resilience of past forest ecosystems and their responses to climate variability. In this paper, we provide a comprehensive overview of the Holocene vegetation history of major western Mediterranean islands, with the twofold aim of examining the timing, extent, and rates of vegetation changes over the last few thousand years, and evaluating the influence of Rapid Climate Changes (RCCs) on forest ecosystems. The rate of change analysis allowed the identification of a distinct pattern of rapid shifts in forest composition, corresponding to periods of climate instability. These shifts align with the periodicity of Bond events, suggesting synchronicity between changes in forest ecosystems and centennial-scale climatic oscillations at a supra-regional scale. A REDFIT spectral analysis applied to palynological proxies of forest cover changes identified prominent periodicities suggesting a direct influence of solar activity and/or a relation with complex ocean–atmosphere circulation mechanisms triggered by global climate forcings. Full article

We present the first fully curated, publicly accessible archive of infrasonic records from ten large bolide events documented by the U.S. Air Force Technical Applications Center’s global microbarometer network between 1960 and 1972. Captured on analog strip-chart paper, these waveforms predate modern digital arrays and space-based sensors, making them a unique window on meteoroid activity in the mid-twentieth century. Prior studies drew important scientific conclusions from the records but released only limited artifacts, chiefly period–amplitude tables and unprocessed scans, leaving the underlying data inaccessible for independent study. The present release transforms those limited excerpts into a research-ready resource. By capturing ten large events in the mid-20th century, the dataset constitutes a critical reference point for assessing bolide activity before the advent of modern space-based and digital ground-based monitoring. The multi-year coverage and worldwide distribution of events provide a valuable reference for comparing past and more recent detections, facilitating assessments of long-term flux and the dynamics of acoustic wave propagation in Earth’s atmosphere. The dataset’s availability in a consolidated format ensures straightforward access to waveforms and derived measurements, supporting a wide range of scientific inquiries into bolide physics and infrasound monitoring. By preserving these historical acoustic observations, the collection maintains a significant record of mid-20th-century meteoroid entries. It thereby establishes a basis for further refinement of impact hazard evaluations, contributes to historical continuity in atmospheric observation, and enriches the study of meteoroid-generated infrasound signals on a global scale. Full article

Biosphere Reserves (BRs) represent dynamic spaces where the interdependence between nature and people is actively shaped and preserved. These territories serve as living laboratories for sustainable development, blending conservation efforts with local knowledge and cultural traditions. This paper explores how BRs exemplify the interconnection between ecological resilience and biocultural heritage, demonstrating the value of integrating traditional practices into contemporary sustainability frameworks. Using insights from the Memories of Biosphere Reserves project, which has collected over 370 testimonies from Portugal, Brazil, and São Tomé e Príncipe, this study highlights the role of memory and storytelling in reinforcing socio-ecological resilience and informing participatory conservation governance. By documenting personal experiences, traditional land-use practices, and community perceptions, these testimonies foster empathy, intergenerational learning, and ethical engagement with the environment. They also provide crucial knowledge for environmental stewardship and community-driven sustainability strategies. The article further examines the transformative role of digital technologies, open science, and artificial intelligence in preserving and disseminating biocultural heritage. Through georeferenced digital archives and participatory research, communities safeguard their cultural and ecological heritage, ensuring knowledge transmission across generations. By positioning BRs as models for integrated conservation and development, this paper underscores the importance of interconnected socio-ecological systems in achieving sustainability goals. The findings suggest that valuing and preserving biocultural heritage within BRs not only strengthens community identity and resilience, but also provides actionable pathways for addressing contemporary environmental challenges. Full article

Post-industrial and post-mining areas are an important element of cities historically associated with industrial activity. The transformation of degraded areas is a challenge for spatial policy, which is characterized by a substantial impact on the cultural heritage of mining and industry. The case of Piekary Śląskie shows the consequences of deindustrialization, which leads to the degradation of urban space and requires innovative revitalization strategies considering the principles of sustainable development and the concept of blue–green infrastructure. Archived topographic maps and current interactive maps of the study city were used in a spatial data analysis. The aim was to determine the directions of the spatial development of post-industrial and post-mining areas using the example of a medium-sized city located in the core of the Katowice conurbation, while considering the role of blue–green infrastructure in the revitalization process. Integrating blue–green infrastructure into the city’s planning documents may serve as a model for other urban areas, highlighting the synergy benefits between urban development and environmental protection. Such solutions support the development of a green economy to improve residents’ living conditions and increase the city’s competitiveness in the region. The specific examples of the revitalization of the areas in the Andaluzja and Julian mines and the reclamation of the brickyard in the area of Kozłowa Góra in Piekary Śląskie show that a multifunctional approach to revitalization contributes to the harmonious development of urban spaces. Full article

Trees mediate critical biogeochemical cycles involving nutrients, pollutants, water, and energy at the interface between terrestrial biosphere and atmosphere. Forest ecosystems significantly influence the global cycling of mercury (Hg), serving as important sinks and potential sources of re-emission through various biotic and abiotic processes. Anthropogenic Hg emissions, predominantly from industrial activities, mining, and fossil fuel combustion, have substantially altered the natural Hg cycle, intensifying ecotoxicological concerns and establishing forests as primary routes for atmospheric Hg deposition into terrestrial reservoirs. This perturbation profoundly affects global atmospheric Hg concentrations, residence times, and spatial distribution patterns. While early investigations focused on forest stands near heavily polluted areas, contemporary research has expanded to diverse ecosystems, revealing that trees provide tissues that function as temporal archives for atmospheric-terrestrial Hg exchange. Leaves capture high-resolution records of contemporary Hg dynamics at sub-annual timescales, whereas annual growth rings preserve multi-decadal chronologies of historical atmospheric exposure. Incorporating this dual temporal perspective is crucial for analysing Hg deposition trends and assessing the efficacy of environmental policies designed to control and mitigate Hg pollution. This review critically evaluates recent developments concerning the ecophysiological determinants of Hg accumulation in trees, highlighting how combined foliar and dendrochemical analytical methods strengthen our mechanistic understanding of vegetation-atmosphere Hg exchange. To enhance biomonitoring approaches, we emphasised the need for methodological standardisation, deeper integration of ecophysiological variables, and consideration of climate change implications as priority research areas. Furthermore, integrating Hg measurements with functional markers (δ¹³C and δ¹⁸O) and Hg isotope analyses strengthens the capacity to differentiate between physiological and environmental influences on Hg accumulation, thereby refining the mechanistic framework underlying effective tree-based Hg biomonitoring. Full article