Search Results (2,760)

Background: Robot-assisted surgery (RAS) is a major innovation in the treatment of lung cancer, offering advantages in surgical precision and reducing postoperative complications. However, its impact on 90-day mortality remains controversial due to methodological biases in comparative studies. This study uses machine learning methods to improve propensity score estimation and reduce selection bias. Methods: We used the French national hospital database (PMSI) to identify patients who underwent lung resection for cancer between 2019 and 2023. Four models were applied for propensity score estimation: logistic regression, Random Forest, Gradient Boosting Machine (GBM), and XGBoost. Group balancing was achieved through propensity score weighting and matching, followed by logistic regression analysis to estimate the effect of RAS on 90-day mortality. Results: Among the 30,988 patients included, 5717 (18.5%) underwent robot-assisted surgery, while 25,271 (81.5%) underwent thoracotomy. RAS patients had a lower prevalence of comorbidities and earlier-stage tumors. XGBoost was the most effective model for propensity score estimation, with an AUC ROC of 0.9984 and a Brier Score of 0.0119. The adjusted analysis showed a significant reduction in 90-day mortality in the RAS group (OR = 0.39, 95% CI: 0.34–0.45) with weighting and (OR = 0.58, 95% CI: 0.48–0.70) with matching. Conclusions: The application of machine learning to adjust for selection bias allowed for better control of confounding factors in the analysis of the effect of RAS on 90-day mortality. Our results suggest a potential benefit of robotic surgery compared to thoracotomy, although further studies are needed to confirm these findings. Full article

The GFED (Global Fire Emissions Database) series products are widely used in global fire research, yet their applicability in mainland China remains insufficiently evaluated. Additionally, large fires and small fires are rarely studied separately. This study first evaluates GFED4’s applicability for monitoring forest fire burned areas in Chinese mainland (2001–2015) through multi-temporal (annual, seasonal, and monthly) and multi-spatial (national, regional, provincial, and 0.25° grid) analyses, using Pearson correlation (CC), root mean square error (RMSE), and mean error (ME) alongside official statistical data. Then, the forest fire-burned areas of small fires were extracted based on the difference between GFED4 and GFED5. The results show that GFED4 exhibits strong consistency at the national level and in key fire-prone regions such as Northeast, North, and Central South China, especially during high-fire years and in spring. However, systematic overestimation occurs in the Northwest, while underestimation or seasonal bias is observed in parts of East and Southwest China. The results show a clear decline in large-fire burned area, but a significant increase in small fires, particularly in Northeast, Central South, and East China. Spatial analysis indicates small fires exhibit strong clustering (Moran’s I = 0.270, p < 0.01), whereas large fires are spatially dispersed. The study concludes that GFED4 is reliable for monitoring large fires in forested zones but should be applied cautiously in non-forested and small-fire-dominated regions. Full article

The Hurst parameter H plays a critical role in modeling long-memory behavior in financial time series, particularly within the framework of the fractional Black–Scholes model (fBSM). While the Method of Moments (MOM) provides a fast, closed-form estimator for H, it suffers from increasing negative bias, especially as H grows beyond 0.6. This paper proposes a bias-corrected version of the MOM estimator based on a quadratic regression fit derived from simulation data. The corrected estimator substantially reduces estimation error while retaining computational efficiency. Through extensive simulations, we quantify the impact of MOM bias on option pricing and demonstrate how our correction method leads to more accurate pricing under the fBSM. We apply the methodology to real financial assets—including Natural Gas, Apple, Gold, and Crude Oil—and show that the corrected Hurst estimates reduce option pricing error by up to USD 0.47 per contract relative to the uncorrected estimator, depending on the asset’s volatility structure. These results underscore the importance of accurate Hurst parameter estimation for derivative pricing, particularly in volatile markets such as energy and commodities, while also remaining relevant to equities and precious metals. The corrected estimator thus offers practitioners a simple yet effective tool to improve financial decision-making. Full article

Background: The relationship between orthodontics and endodontics during the treatment planning phase is scarcely investigated, especially when orthodontic treatment is considered for endodontically treated teeth with apical periodontitis. This systematic review aimed to investigate the effect of orthodontic movement on the periapical healing of teeth that have undergone endodontic root canal treatment/retreatment. Materials and methods: On 15 March 2025, a systematic search was conducted in PubMed, Web of Science Core Collection, EBSCO host and complemented with a manual search of Google Scholar and the gray literature. The quality and the risk of bias of the included studies were assessed using the Joanna Briggs Critical Appraisal tools for human studies and the Systematic Review Centre for Laboratory Animal Experimentation for animal studies. The data about the influence of orthodontic movement on the periapical healing of endodontically treated teeth were extracted and pooled. Results: Out of 4614 identified titles, 6 studies were finally included (two animal and four clinical studies). The risk of bias was high in one study, moderate in three, and low in two. The included animal studies demonstrated a significant delay in the healing process of periapical lesions when orthodontic forces were applied shortly after root canal treatment. However, clinical studies showed no significant impact of orthodontic movement on periapical radiolucency except when the quality of obturation was compromised. Conclusions: Current clinical studies indicate that orthodontic tooth movement does not impair the periapical healing of endodontically treated teeth when the root canal obturation is of adequate quality. Full article

Background/Objective: Dental implant therapy requires clinicians to identify edentulous regions and adjacent teeth accurately to ensure precise and efficient implant placement. However, this process is time-consuming and subject to operator bias. To address this challenge, this study proposes an AI-assisted detection framework that integrates deep learning and image processing techniques to predict implant placement pathways on dental panoramic radiographs, supporting clinical decision-making. Methods: The proposed framework is first applied to YOLO models to detect edentulous regions and employs image enhancement techniques to improve image quality. Subsequently, YOLO-OBB is utilized to extract pixel-level positional information about neighboring healthy teeth. An implant pathway orientation visualization algorithm is applied to derive clinically relevant implant placement recommendations. Results: Experimental evaluation using YOLOv9m and YOLOv8n-OBB demonstrated stable performance in both recognition and accuracy. The models achieved Precision values of 88.86% and 89.82%, respectively, with an average angular error of only 1.537° compared to clinical implant pathways annotated by dentists. Conclusions: This study presents the first AI-assisted diagnostic framework for DPR-based implant pathway prediction. The results indicate strong consistency with clinical planning, confirming its potential to enhance diagnostic accuracy and provide reliable decision support in implant dentistry. Full article

Current InVEST habitat quality assessments rely heavily on subjective expert judgment for parameter specification, introducing substantial uncertainty and limiting their regional applicability. To address this gap, we developed an objective, statistically rigorous framework for parameter derivation by integrating Principal Component Analysis (PCA), Structural Equation Modeling (SEM), and spatial analysis, supported by high-resolution biotope mapping. The methodology was applied to Gochang-gun, South Korea, where nine threat factors were analyzed using empirical data from 6633 sampling points. PCA identified threat groupings, SEM quantified habitat–threat relationships for sensitivity derivation, and variogram analysis determined maximum influence distances, while 1:5000 scale biotope maps incorporating 14 ecological indicators replaced conventional land cover classifications. These empirically derived parameters were directly incorporated into the InVEST Habitat Quality model, replacing default or expert-based values. As a result, the biotope-based InVEST HQ implementation achieved exceptional performance (R² = 0.892) with crops emerging as the dominant threat factor (sensitivity = 1.000, weight = 34.1%). Compared to the land use/land cover (LULC)-based approach using conventional parameterization, the biotope–PCA–SEM model demonstrated higher predictive accuracy (AUC = 0.805 vs. 0.755), stronger correlations with independent conservation indicators (protected area correlation: 0.457 vs. 0.201), and clearer ecological gradients across UNESCO Biosphere Reserve zones. This framework eliminates subjective bias while maintaining regional specificity, establishing a transferable foundation for evidence-based conservation planning. By demonstrating substantial improvements over conventional parameterization, the study highlights the inadequacy of transferred parameters and provides an objective standard for advancing InVEST applications worldwide. Full article

The growing diversity of cloud services has made evaluating their relative merits in terms of price, functionality, and availability increasingly complex, particularly given the wide range of deployment alternatives and service capabilities. Cloud manufacturing often requires the integration of multiple services to accomplish user tasks, where the effectiveness of resource utilization and capacity sharing is closely tied to the adopted service composition strategy. This complexity, intensified by competition among providers, renders cloud service selection and composition an NP-hard problem involving multiple challenges, such as identifying suitable services from large pools, handling composition constraints, assessing the importance of quality-of-service (QoS) parameters, adapting to dynamic conditions, and managing abrupt changes in service and network characteristics. To address these issues, this study applies the Technique for Order Preference by Similarity to an Ideal Solution (TOPSIS) in conjunction with Multi-Criteria Decision Making (MCDM) to evaluate and rank cloud services, while the Analytic Hierarchy Process (AHP) combined with the entropy weight method is employed to mitigate subjective bias and improve evaluation accuracy. Building on these techniques, a novel Adaptive Multi-Level Linked-Priority-based Best Method Selection with Multistage User-Feedback-driven Cloud Service Composition (MLLP-BMS-MUFCSC) framework is proposed, demonstrating enhanced service selection efficiency and superior quality of service compared to existing approaches. Full article

In this paper, we demonstrated a high-sensitivity polarization image sensor for millimeter-wave electric field imaging using electro-optic crystals. We developed a three-layer on-pixel polarizer structure fabricated with a 0.35-µm standard CMOS process, achieving an extinction ratio of 5.7, which corresponds to a 73% improvement over previous two-layer structure. Crosstalk reduction was implemented by applying a bias voltage to the n-well pixel separation, and extinction ratio was further improved. By using an improved sensor, it demonstrated a 7.6 dB SNR improvement in 30 GHz electric field imaging compared to previous sensors, despite 30% transmittance reduction. Angular dependence analysis confirmed adequate performance within the optical system’s constraints. These results enable high-speed and high-sensitivity millimeter-wave imaging applications. Full article

In this paper, a reduced-complexity cross-domain iterative detection for orthogonal time frequency space (OTFS) modulation is proposed that exploits channel properties in both time and delay–Doppler domains. Specifically, we first show that in the time-domain effective channel, the path delay only introduces interference among samples in adjacent time slots, while the Doppler becomes a phase term that does not affect the channel sparsity. This investigation indicates that the effects of delay and Doppler can be decoupled and treated separately. This “band-limited” matrix structure further motivates us to apply a reduced-size linear minimum mean square error (LMMSE) filter to eliminate the effect of delay in the time domain, while exploiting the cross-domain iteration for minimizing the effect of Doppler by noticing that the time and Doppler are a Fourier dual pair. Furthermore, we apply eigenvalue decomposition to the reduced-size LMMSE estimator, which makes the computational complexity independent of the number of cross-domain iterations, thus significantly reducing the computational complexity. The bias evolution and variance evolution are derived to evaluate the average MSE performance of the proposed scheme, which shows that the proposed estimators suffer from only negligible estimation bias in both time and DD domains. Particularly, the state (MSE) evolution is compared with bounds to verify the effectiveness of the proposed scheme. Simulation results demonstrate that the proposed scheme achieves almost the same error performance as the optimal detection, but only requires a reduced complexity. Full article

Background: Artificial Intelligence (AI) is increasingly applied in endurance sports to optimize performance, enhance recovery, and personalize nutrition and supplementation. This review synthesizes current knowledge on AI applications in endurance sports, emphasizing implications for metabolic health, nutritional strategies, and recovery optimization, while also addressing ethical considerations and future directions. Methods: A narrative review was conducted using targeted searches of PubMed, Scopus, and Web of Science with cross-referencing. Extracted items included sport/context, data sources, AI methods including machine learning (ML), validation type (internal vs. external/field), performance metrics, comparators, and key limitations to support a structured synthesis; no formal risk-of-bias assessment or meta-analysis was undertaken due to heterogeneity. Results: AI systems effectively integrate multimodal physiological, environmental, and behavioral data to enhance metabolic health monitoring, predict recovery states, and personalize nutrition. Continuous glucose monitoring combined with AI algorithms allows precise carbohydrate management during prolonged events, improving performance outcomes. AI-driven supplementation strategies, informed by genetic polymorphisms and individual metabolic responses, have demonstrated enhanced ergogenic effectiveness. However, significant challenges persist, including measurement validity and reliability of sensor-derived signals and overall dataset quality (e.g., noise, missingness, labeling error), model performance and generalizability, algorithmic transparency, and equitable access. Furthermore, limited generalizability due to homogenous training datasets restricts widespread applicability across diverse athletic populations. Conclusions: The integration of AI in endurance sports offers substantial promise for improving performance, recovery, and nutritional strategies through personalized approaches. Realizing this potential requires addressing existing limitations in model performance and generalizability, ethical transparency, and equitable accessibility. Future research should prioritize diverse, representative, multi-site data collection across sex/gender, age, and race/ethnicity. Coverage should include performance level (elite to recreational), sport discipline, environmental conditions (e.g., heat, altitude), and device platforms (multi-vendor/multi-sensor). Equally important are rigorous external and field validation, transparent and explainable deployment with appropriate governance, and equitable access to ensure scientifically robust, ethically sound, and practically relevant AI solutions. Full article

Sustainable economic development requires transparent and consistent institutional communication from monetary authorities to maintain long-term financial stability and public trust. This study investigates the latent authorial structure and stylistic heterogeneity of central bank communications by applying stylometric analysis and unsupervised machine learning to official announcements of the Central Bank of the Republic of Turkey (CBRT). Using a dataset of 557 press releases from 2006 to 2017, we extract a range of linguistic features at both sentence and document levels—including sentence length, punctuation density, word length, and type–token ratios. These features are reduced using Principal Component Analysis (PCA) and clustered via Hierarchical Clustering on Principal Components (HCPC), revealing three distinct authorial groups within the CBRT’s communications. The robustness of these clusters is validated using multidimensional scaling (MDS) on character-level and word-level n-gram distances. The analysis finds consistent stylistic differences between clusters, with implications for authorship attribution, tone variation, and communication strategy. Notably, sentiment analysis indicates that one authorial cluster tends to exhibit more negative tonal features, suggesting potential bias or divergence in internal communication style. These findings challenge the conventional assumption of institutional homogeneity and highlight the presence of distinct communicative voices within the central bank. Furthermore, the results suggest that stylistic variation—though often subtle—may convey unintended policy signals to markets, especially in contexts where linguistic shifts are closely scrutinized. This research contributes to the emerging intersection of natural language processing, monetary economics, and institutional transparency. It demonstrates the efficacy of stylometric techniques in revealing the hidden structure of policy discourse and suggests that linguistic analytics can offer valuable insights into the internal dynamics, credibility, and effectiveness of monetary authorities. These findings contribute to sustainable financial governance by demonstrating how AI-driven analysis can enhance institutional transparency, promote consistent policy communication, and support long-term economic stability—key pillars of sustainable development. Full article

As universities become increasingly open, campuses are no longer only places for study and daily life for students and faculty, but also essential spaces for public visits and cultural identity. Traditional perception evaluation methods that rely on manual surveys are limited by sample size and subjective bias, making it challenging to reveal differences in experiences between groups (students/visitors) and the complex relationships between spatial elements and perceptions. This study uses a comprehensive open university in China as a case study to address this. It proposes a research framework that combines street-view image semantic segmentation, perception survey scores, and interpretable machine learning with sample augmentation. First, full-sample modeling is used to identify key image semantic features influencing perception indicators (nature, culture, aesthetics), and then to compare how students and visitors differ in their perceptions and preferences across campus spaces. To overcome the imbalance in survey data caused by group–space interactions, the study applies the CTGAN method, which expands minority samples through conditional generation while preserving distribution authenticity, thereby improving the robustness and interpretability of the model. Based on this, attribution analysis with an interpretable decision tree algorithm further quantifies semantic features’ contribution, direction, and thresholds to perceptions, uncovering heterogeneity in perception mechanisms across groups. The results provide methodological support for perception evaluation of campus functional zones and offer data-driven, human-centered references for campus planning and design optimization. Full article

The intrinsic noise of giant magnetoresistive (GMR) sensors is large at low frequencies, and their resolution is inevitably significantly limited. Investigation of GMR noise requires the use of measurement systems that have lower noise than the sample. In this context, the main purpose of this study is to evaluate the effectiveness of two electronic noise measurement configurations of a single GMR sensing element. The first method connects the sample in a voltage divider configuration and the second method connects in a Wheatstone bridge configuration. Three amplification set-ups were investigated: a low-noise amplifier, an ultra-low-noise amplifier and an instrumentation amplifier. Using cross-correlation, the noise of the measurement system introduced by the amplifiers was reduced. Noise spectra were recorded at room temperature in the frequency range of 0.5 Hz to 10 kHz, under different sample bias voltages. The measurements were performed in zero applied magnetic field and in a field corresponding to the maximum sensitivity of the sensor. From the noise spectra, the detectivity of the sensor was determined to be in the 200–300 nT/√Hz range. Good agreement was observed between the results obtained using all three set-ups, suggesting the effectiveness of the noise measurement systems applied to the magnetoresistive sensor. Full article

Background: Parkinson’s disease (PD) is a neurodegenerative disorder for which no curative therapies currently exist. Experimental models employing 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) reproduce PD features such as striatal dopaminergic dysfunction and motor deficits. Various MPTP dosing regimens are used to screen drug candidates for PD, but their validity is limited because of the predominant use of young male animals. Sex bias is another issue that is underrepresented in PD research, since females are more susceptible to this pathology. Here, we studied the model of bolus administration of MPTP (30 mg/kg) in aged female mice and assessed its sensitivity to the antioxidants fullerene C₆₀ and fullerenol C₆₀(OH)₂₄, given that oxidative stress is a key contributor to PD. Methods: 12-month-old female C57BL/6 mice received fullerene (0.1 mg/kg/day, via diet) or fullerenol (0.15 mg/kg/day, via drinking water). On day 10, mice were injected with MPTP. We studied tremor, piloerection, and behavior in the pole test, rotarod, pole test, and open field. High-performance liquid chromatography (HPLC) was employed to study dopaminergic neurotransmission, and the expression levels of its molecular regulators and nitric oxide synthase (NOS)-related targets were investigated using RT-PCR in the striatum and cortex. Results: MPTP-challenged mice displayed profound impairment in markers of dopaminergic neurotransmission and cellular distress, and showed disrupted motor behavior and vegetative functions. Antioxidant-treated animals that received a bolus injection of MPTP demonstrated partial preservation of tremor response, dopaminergic parameters, and iNOS and nNOS gene expression, although motor performance in the pole test was only modestly improved. Fullerenol appeared more effective in decreasing MPTP-induced neurochemical changes. Conclusions: The applied MPTP model showed its validity in mimicking PD features and was sensitive to low doses of antioxidants, suggesting its usefulness for screening drugs that target oxidative and nitrosative stress. The neuroprotective effects of fullerene-based compounds suggest their potential utility in the treatment of PD. Full article

Artificial intelligence tools are quickly being applied in many areas of science, including learning sciences. Learning requires various types of thinking, sustained by distinct sets of neural networks in the brain. Labelling these systems gives us tools to manage them. This paper presents a pilot application of Large Language Models (LLMs) to physics textbook analysis, grounded in a well-developed neural network theory known as the Five Pillars of the Mind. The domain-specific networks, innate sense, and the five pillars provide a framework with which to examine how physics is learnt. For example, one can identify which pillars are active when discussing a physics concept. Identifying which pillars belong to which physics concept may be significantly influenced by the bias of the author and could be too time-consuming for longer, more complex texts involving physics concepts. Therefore, using LLMs to identify pillars could enhance the application of this framework to physics education. This article presents a case study in which we used selected Large Language Models to identify pillars within eight pages of learning material concerning forces aimed at 12- to 14-year-old pupils. We used GPT-4o and o4-mini, as well as MAXQDA AI Assist. Results from these models were compared with the authors’ manual analysis. Precision, recall, and F1-Score were used to evaluate the results quantitatively. MAXQDA AI Assist obtained the best results with 1.00 precision, 0.67 recall, and an F1-Score of 0.80. Both products by OpenAI hallucinated and falsely identified several concepts, resulting in low precision and, consequently, low F1-Score. As predicted, ChatGPT o4-mini scored twice as high as ChatGPT 4o. The method proved to be promising, and its future development has the potential to provide research teams with analysis not only of written learning material, but also of pupils’ written work and their video-recorded activities. Full article