Search Results (59)

Community-Engaged Research (CER) arose as a means of increasing the democratic participation of communities that study outcomes directly impact. CER has been identified as a recommended approach for conducting biomedical and behavioral health research with Black communities, a population that has been excluded from and exploited by academic health research for centuries. However, solely increasing community participation without identifying and redressing racialized power imbalances within community–academic partnerships involving Black populations can stall progress towards racial health equity. The purpose of this study was to explore how power can be redistributed equitably in community–academic health research partnerships involving Black populations. Utilizing the qualitative methodological approach of critical narrative inquiry, counter-stories from 12 Black individuals who have served as community partners on U.S.-based academic health research teams were collected via in-depth semi-structured narrative interviews. A reflexive thematic analysis approach was utilized to identify and analyze strategies expressed by study participants for increasing community agency, efficacy, and solidarity in health research. By centering the voices of Black community members who have directly engaged with academic health research institutions, this study sought to amplify the desires and aspirations of Black communities regarding shifting power in health research processes and outcomes. Full article

This study systematically reviews the academic literature on unpaid care work during and after COVID-19, emphasizing gender dimensions. Using Web of Science (WOS) and SCOPUS, it analyzes 75 empirical articles published between 2020 and 2024 in English and Spanish. The selection focused on studies addressing unpaid care from multiple perspectives, particularly family dynamics. Quantitative analysis examined frequencies and percentages, while qualitative analysis explored content depth. Results reveal a dominant biomedical perspective on care, often neglecting emotional well-being and broader socioeconomic impacts. The present study also identifies a lack of critical reflection on care’s gendered nature and unequal caregiving responsibilities. Women, historically burdened with care duties, faced increased domestic demands during the pandemic, due to school closures and limited services, exacerbating gender inequality and reducing workforce participation. A bibliometric analysis of research on COVID-19, gender, and social care highlights limited collaboration, with studies fragmented across research groups and lacking international co-authorship. This study calls for governmental and international initiatives to foster cross-border collaboration, enabling a more comprehensive understanding of care that integrates emotional and socioeconomic aspects alongside health concerns. This would promote a more inclusive and reflective approach to unpaid caregiving research. Full article

With the advantages of simple structure, low power consumption, no electromagnetic interference, and fast response, piezoelectric pumps (PPs) have been widely used in the fields of chip cooling, biomedical applications, chemical applications, and fuel supply applications. In recent decades, scholars have proposed various PPs, and this article reviews the recent research results. In this review, according to the “valve” structure, PPs are divided into valve-less piezoelectric pumps (VLPPs), valve-based piezoelectric pumps (VBPPs), and piezoelectric pumps with valve and valve-less state transitions (PPVVSTs). Firstly, the design methods of typical structures were discussed, and comparisons were made in terms of driving frequency, driving voltage, output pressure, flow rate, structure materials, and pump size. The advantages and disadvantages of VLPPs, VBPPs, and PPVVSTs were analyzed. Then, we compared the driving parameters, output performance, structure materials, and pump size of single-chamber piezoelectric pumps (SCPs) and multi-chamber piezoelectric pumps (MCPs) and analyzed the advantages and disadvantages of SCPs and MCPs. Optimization methods proposed in recent years have been summarized to address the issues of the cavitation phenomenon, the liquid back-flow problem, and low output performance in PPs. Subsequently, the application research of PPs and the distribution of academic achievements were discussed. Finally, this review was summarized, and future research hot spots for PPs were proposed. The main contribution of this review is to provide piezoelectric pump (PP) researchers with a certain understanding of the structural design, optimization methods, practical applications, and research distribution of PPs, which can provide theoretical guidance for future research. Full article

This research aims to investigate the roles of ontology and Semantic Web Technologies (SWT) in modern knowledge representation and data management. By analyzing a dataset of 10,037 academic articles from Web of Science (WoS) published in the last 6 years (2019–2024) across several fields, such as computer science, engineering, and telecommunications, our research identifies important trends in the use of ontologies and semantic frameworks. Through bibliometric and semantic analyses, Natural Language Processing (NLP), and topic modeling using Latent Dirichlet Allocation (LDA) and BERT-clustering approach, we map the evolution of semantic technologies, revealing core research themes such as ontology engineering, knowledge graphs, and linked data. Furthermore, we address existing research gaps, including challenges in the semantic web, dynamic ontology updates, and scalability in Big Data environments. By synthesizing insights from the literature, our research provides an overview of the current state of semantic web research and its prospects. With a 0.75 coherence score and perplexity = 48, the topic modeling analysis identifies three distinct thematic clusters: (1) Ontology-Driven Knowledge Representation and Intelligent Systems, which focuses on the use of ontologies for AI integration, machine interpretability, and structured knowledge representation; (2) Bioinformatics, Gene Expression and Biological Data Analysis, highlighting the role of ontologies and semantic frameworks in biomedical research, particularly in gene expression, protein interactions and biological network modeling; and (3) Advanced Bioinformatics, Systems Biology and Ethical-Legal Implications, addressing the intersection of biological data sciences with ethical, legal and regulatory challenges in emerging technologies. The clusters derived from BERT embeddings and clustering show thematic overlap with the LDA-derived topics but with some notable differences in emphasis and granularity. Our contributions extend beyond theoretical discussions, offering practical implications for enhancing data accessibility, semantic search, and automated knowledge discovery. Full article

Background/Objective: In nursing practice, differences have been noted between the shared habitus acquired during academic training and professional practices within healthcare systems. In this context, nurses tend to experience an impact on their autonomy due to the ways in which their professional habitus has been established, which, in some way, alters the cultural capital acquired during their academic training. The objective of this study was to identify factors that facilitate and/or limit autonomy in nursing practice based on professional habitus. Method: This research was conducted using a hermeneutic qualitative study framed within a critical approach that incorporated Bourdieu’s theory of fields (habitus, field, and capital). This study included 11 registered nurses working in hospital settings, 17 nursing students, and six university professors. Data collection included 34 sociodemographic forms, 34 individual semi-structured interviews, and five focus group discussions conducted with an interview guide. The collected data were analyzed using an interpretative hermeneutic approach, integrating grounded theory and Bourdieu’s theory of fields, focusing on the concepts of habitus, field, and capital. Results: This study identified a central theme—clarification of the nurse’s role (professional habitus)—alongside three subthemes: (1) strengthening the nursing identity (identity habitus), (2) optimizing nursing education (optimization habitus), and (3) reinforcing professional credibility (validation habitus). Autonomy was found to be influenced by hierarchical structures, power relations, and institutional constraints within the healthcare social field, which led to limitations in the accumulation of nurses’ symbolic capital. Conclusions: The professional habitus of nurses is shaped by various elements within the healthcare social field. This field is constrained by hierarchical structures and factors such as subordination to the hegemonic biomedical discourse and the medical profession, limited recognition of humanized care, institutional restrictions on acknowledging the nursing process, and a lack of solidarity and leadership. These constraints ultimately hinder the accumulation of symbolic and social capital in nursing, leading to a loss of autonomy and hindering professional development. Full article

Mitochondria, as vital organelles, play a central role in subcellular research and biomedical innovation. Although functional nucleic acid (FNA) nanostructures have witnessed remarkable progress across numerous biological applications, strategies specifically tailored to target mitochondria for molecular imaging and therapeutic interventions remain scarce. This review delves into the latest advancements in leveraging FNA nanostructures for mitochondria-specific imaging and cancer therapy. Initially, we explore the creation of FNA-based biosensors localized to mitochondria, enabling the real-time detection and visualization of critical molecules essential for mitochondrial function. Subsequently, we examine developments in FNA nanostructures aimed at mitochondrial-targeted cancer treatments, including modular FNA nanodevices for the precise delivery of therapeutic agents and programmable FNA nanostructures for disrupting mitochondrial processes. Emphasis is placed on elucidating the chemical principles underlying the design of mitochondrial-specific FNA nanotechnology for diverse biomedical uses. Lastly, we address the unresolved challenges and outline prospective directions, with the goal of advancing the field and encouraging the creation of sophisticated FNA tools for both academic inquiry and clinical applications centered on mitochondria. Full article

The advancement of 3D printing technology has changed material design and fabrication across various industries. Among its many applications, the development of high-wear-resistance polymer composites, particularly using Fused Deposition Modelling (FDM), has received increasing interest from both academic and industrial sectors. This paper provides an overview of recent advances in this field, focusing on the selection of key printing parameters (such as layer thickness, print speed, infill density, and printing temperature) and material compatibility optimisation to enhance print quality and tribological performance. The effects of various tribo-fillers, such as fibres and nanoparticles, on the tribological properties of the printed polymer composites were studied. Generally, in the case of nano-sized particles, the wear rate can be reduced by approximately 3 to 5 times when the nanoparticle content is below 5 vol.%. However, when the nanoparticle concentration exceeds 10 vol.%, wear resistance may deteriorate due to the formation of agglomerates, which disrupts the uniform dispersion of reinforcements and weakens the composite structure. Similarly, in short fibre-reinforced polymer composites, a fibre content of 10–30 vol.% has been observed to result in a 3 to 10 times reduction in wear rate. Special attention is given to the synergistic effects of combining micro- and nano-sized fillers. These advancements introduce novel strategies for designing wear-resistant polymer composites without requiring filament fabrication, making 3D printing more accessible for tribological applications. In the last part of the review, the impact of emerging AI technologies on the field is also reviewed and discussed. By identifying key research gaps and future directions, this review aims to drive further innovation in the development of durable, high-performance materials for wide industry applications in aerospace, biomedical, and industrial engineering. Full article

The issue of suicide has garnered considerable attention in refugee scholarship, where research examines how unique forced migration and resettlement challenges exacerbate risks and vulnerabilities to suicide. However, there are gaps in understanding the social and cultural factors shaping the lived experience of suicide in refugee communities. Using the example of young people of African backgrounds in Australia, this paper presents a collaboration among two academics and two South Sudanese youth advocates to explore the sociocultural factors impacting suicidality through reflexive discussions and collaborative poetry. This combined approach offered a unique and nuanced conceptual and methodological framework to contribute culturally specific narratives to critical suicide studies and challenge western-centric and biomedical perspectives on suicide. The process highlighted (i) the lack of dialogue about suicide in the South Sudanese community and (ii) the absence of community-based support structures to address suicide. This paper provides useful insights into the culturally specific context of suicide, adding refugee perspectives to the discipline of critical suicide studies. Full article

Cell culture banks play a crucial role in advancing biomedical research by providing standardized, reproducible biological materials essential for various applications, from drug development to regenerative medicine. This opinion article presents a comprehensive overview of cell culture banks, exploring their establishment, maintenance, and characterization processes. The significance of ethical considerations and regulatory frameworks governing the use of cell lines is discussed, emphasizing the importance of quality control and validation in ensuring the integrity of research outcomes. Additionally, the diverse types of cell culture banks—primary cells, immortalized cell lines, and stem cells—and their specific contributions to different fields such as cancer research, virology, and tissue engineering are examined. The impact of technological advancements on cell banking practices is also highlighted, including automation and biobanking software that enhance efficiency and data management. Furthermore, challenges faced by researchers in accessing high-quality cell lines are addressed, along with proposed strategies for improving collaboration between academic institutions and commercial entities. By unlocking the potential of cell culture banks through these discussions, this article aims to underline their indispensable role in driving innovation within biomedical research and fostering future discoveries that could lead to significant therapeutic breakthroughs. Full article

For decades, the discoverability and visibility of a paper relied on the readership of the academic journal where the publication was issued. As public interest in biomedicine has grown, the news media have taken on an important role in spreading scientific findings. This investigation explores the potential impact of news media stories on the citations and altmetrics of a paper. A total of 2020 open-access biomedical research papers, all published in the same year, 2015, and in journals with an impact factor between 10 and 14, were investigated. The papers were split into two groups based on the sole criterion of receiving or not receiving news media coverage. Papers with news media coverage accounted for 44% of the total. They received, on average, 60% more citations, 104% more blogs, 150% more X posts, 106% more Facebook reports, 40% more Wikipedia references, 85% more videos, and 51% more Mendeley readers than papers without news media coverage. The correlation between news media outlets and increased citations and altmetrics is evident. However, the broader societal impact of news media coverage, in terms of bringing scientific matters or discoveries to the public eye, appears to be more robust when compared to the reactions of the scientific community. Full article

This article will use syndemic theory to identify and analyze overlapping health and social conditions, focusing specifically on how gender-based violence is systemically interconnected with contemporary public health issues. The overdose death crisis that continues to afflict Canadian populations is not an isolated health issue. Across Canada, it is intertwined with mental health, HIV/AIDS, COVID-19 and structural violence—the chronic and systemic disadvantages affecting those living in poverty and oppressive circumstances. Opioid use is an often-avoidant coping strategy for many experiencing the effects of trauma, relentless fear, pain, ill health and social exclusion. In particular, Indigenous and non-Indigenous women’s experiences with opioid addiction are entangled with encounters with gender based-violence, poverty and chronic ailments within structurally imposed processes and stressors shaped by a history of colonialism, ruptured lifeways and Western ways of knowing and doing, leading to disproportionate harms and occurrences of illness. While biomedical models of comorbidity and mortality approach substance misuse, gender-based violence and major infectious diseases such as HIV/AIDS and COVID-19 as distinct yet compounding realities, this article argues that these conditions are synergistically interrelated via the critical/reflexive lens of syndemic frameworks. Through secondary research using academic, media and policy sources from the past decade in Canada, complemented by prior ethnographic research, the synergistic connections among opioid addiction, gender-based violence and the effects of the COVID pandemic on diverse women will be shown to be driven by socio-structural determinants of health including poverty, intergenerational trauma, the legacy of colonialism and Western optics. Together, they embody a contemporary Canadian syndemic necessitating coordinated responses. Full article

As per the World Health Organization (WHO), antimicrobial resistance (AMR) is a natural phenomenon whereby microbes develop or acquire genes that render them resistant. The rapid emergence and spread of this phenomenon can be attributed to human activity specifically, the improper and excessive use of antimicrobials for the treatment, prevention, or control of infections in humans, animals, and plants. As a result of this factor, many antibiotics have reduced effectiveness against microbes or may not work fully. Thus, there is a pressing need for the development of new antimicrobial agents in order to counteract antimicrobial resistance. Metallic nanoparticles (MNPs) are well known for their broad antimicrobial properties. Consequently, the use of MNPs with current antibiotics holds significant implications. MNPs, including silver nanoparticles (AgNPS), zinc oxide nanoparticles (ZnONPs), copper nanoparticles (CuNPs), and gold nanoparticles (AuNPs), have been extensively studied in conjunction with antibiotics. However, their mechanism of action is still not completely understood. The interaction between these MNPs and antibiotics can be either synergistic, additive, or antagonistic. The synergistic effect is crucial as it represents the desired outcome that researchers aim for and can be advantageous for the advancement of new antimicrobial agents. This article provides a concise and academic description of the recent advancements in MNP and antibiotic conjugates, including their mechanism of action. It also highlights their possible use in the biomedical field and major challenges associated with the use of MNP–antibiotic conjugates in clinical practice. Full article

Gallium (Ga)-based liquid metals (LMs), as an emerging functional material, stand out among many candidates due to their combination of fluidic and metallic attributes, and they have extensively attracted the attention of academic researchers. When fabricated into droplet form, these metals are imbued with many fantastic characteristics, such as a high specific surface area and self-healing properties. Additionally, Ga-based liquid metal droplets (LMDs) achieve higher response accuracy to external stimuli, satisfying the demands of many applications requiring micro-size and precise stimulus-responsivity. Herein, we focus on reviewing the properties of Ga-based LMs and their droplets, the fabrication strategies of metal droplets, their stimulus-response motion under different external fields, and their applications in microfluidic systems, biomedical applications, and micromachines. To further advance the development of responsive Ga-based LMDs, the future outlooks with key challenges related to their further applications are also presented here. Full article

Recently proposed legal frameworks for Artificial Intelligence (AI) depart from some frameworks of concepts regarding ethical and trustworthy AI that provide the technical grounding for safety and risk. This is especially important in high-risk applications, such as those involved in decision-making support systems in the biomedical domain. Frameworks for trustworthy AI span diverse requirements, including human agency and oversight, technical robustness and safety, privacy and data governance, transparency, fairness, and societal and environmental impact. Researchers and practitioners who aim to transition experimental AI models and software to the market as medical devices or to use them in actual medical practice face the challenge of deploying processes, best practices, and controls that are conducive to complying with trustworthy AI requirements. While checklists and general guidelines have been proposed for that aim, a gap exists between the frameworks and the actual practices. This paper reports the first scoping review on the topic that is specific to decision-making systems in the biomedical domain and attempts to consolidate existing practices as they appear in the academic literature on the subject. Full article

Although American Indian and Alaska Native (AIAN) students are the most underrepresented group in the U.S. in biomedical and health sciences relative to population size, little is known about long-term research education programs and outcome tracking. For over 20 years, the Partnership for Native American Cancer Prevention (NACP) has been supported under the National Cancer Institute’s (NCI)-funded Comprehensive Partnerships to Advance Cancer Health Equity (CPACHE) program. Programming included hands-on mentored research and an array of development opportunities. A validated tracking system combining participation records, institutional records, and enrollment/degree attainment from the National Student Clearinghouse documents outcomes. Collectively (2002–2022) NACP engaged 367 AIAN trainees, of whom 237 individuals earned 220 bachelors, 87 masters, and 34 doctoral/professional degrees. Approximately 45% of AIAN doctoral recipients are currently engaged in academic or clinical work, and 10% in industry or tribal leadership. A total of 238 AIAN students participated in mentored research, with 85% demonstrating strong outcomes; 51% attained a degree, and 34% are currently enrolled. Implementation of a robust tracking system documented acceleration in degree attainment over time. Next steps will evaluate the most impactful training activities on student outcomes. Full article