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50 pages, 1936 KiB  
Review
Triathlon: Ergo Nutrition for Training, Competing, and Recovering
by Álvaro Miguel-Ortega, María-Azucena Rodríguez-Rodrigo, Juan Mielgo-Ayuso and Julio Calleja-González
Nutrients 2025, 17(11), 1846; https://doi.org/10.3390/nu17111846 - 28 May 2025
Viewed by 2316
Abstract
Triathlon is a multi-sport event that combines swimming, cycling and running. The distances vary and the physiological demands are high. Objectives: This review compiles information on nutritional strategies and ergogenic supplements for triathlon training, competition and recovery. It aims to provide an [...] Read more.
Triathlon is a multi-sport event that combines swimming, cycling and running. The distances vary and the physiological demands are high. Objectives: This review compiles information on nutritional strategies and ergogenic supplements for triathlon training, competition and recovery. It aims to provide an understanding of the specific challenges and needs of the sport to help triathletes and coaches optimise performance through effective training and nutrition plans. Methods: English-language publications were searched using the keywords triathlon, nutrition, recovery and ergogenic aids, alone or in combination, in databases. Results: Maintaining good glycogen levels, consuming enough carbohydrates and staying properly hydrated are key to athletic performance, especially for triathletes. Education regarding nutrition, the role of probiotics and supplements, and diet modification for the enhancement of performance and recovery are pivotal considerations. Conclusions: Triathletes are at risk of RED-S due to negative energy balance and high fibre/plant protein diets, especially women. Optimising muscle glycogen through tailored diet and training, especially pre- and in-race nutrition, including carbohydrate loading and hydration strategies, is critical. Education is needed to improve post-exercise nutrition, while probiotics and certain supplements may aid performance and recovery. Dietary support is important for resistance training to optimise performance and recovery. Full article
(This article belongs to the Special Issue New Strategies in Sport Nutrition: Enhancing Exercise Performance)
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22 pages, 19413 KiB  
Article
From Density to Efficiency: Exploring Urban Building Use Efficiency in 35 Large Chinese Cities
by Tingting He, Shanshan Cao, Youpeng Lu, Maoxin Zhang, Andong Guo and Boyu Liu
Buildings 2025, 15(11), 1803; https://doi.org/10.3390/buildings15111803 - 24 May 2025
Viewed by 437
Abstract
Efficient urban land use is essential for sustainable urban growth. However, the efficiency of buildings in carrying urban functions remains poorly understood. A comprehensive approach for measuring urban building use efficiency (UBUE) and marginal effect was developed by quantifying the relationship between building [...] Read more.
Efficient urban land use is essential for sustainable urban growth. However, the efficiency of buildings in carrying urban functions remains poorly understood. A comprehensive approach for measuring urban building use efficiency (UBUE) and marginal effect was developed by quantifying the relationship between building volume and urban function. The intensity of urban function was calculated from nighttime light intensity, population density, and facility density. The UBUE at national and urban scales was assessed for 35 Chinese cities. Three significant findings emerge. First, UBUE shows significant spatial variation at national and urban scales, with a maximum disparity of 4.3 times among the 35 cities and a gradual decline along the urban–rural gradient within urban areas. Second, in cities in the western and northeastern areas, a smaller amount of urban function was generated per unit of newly constructed building volume, indicating that newly increased buildings are less efficient. Third, the scaling exponents of most cities were less than one, suggesting a marginal diminishing effect in the relationship between urban function and building volume. The marginal diminishing effect was more pronounced in economically developed cities. The comprehensive investigation of the relationship between urban function and building volume provides a scientific basis for land development allocation policies and urban growth regulation. Full article
(This article belongs to the Section Building Energy, Physics, Environment, and Systems)
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25 pages, 1609 KiB  
Review
Ergonutrition Supplementation and Recovery in Water Polo: A Systematic Review
by Álvaro Miguel-Ortega, Josu Barrenetxea-Garcia, María-Azucena Rodríguez-Rodrigo, Enrique García-Ordóñez, Juan Mielgo-Ayuso and Julio Calleja-González
Nutrients 2025, 17(8), 1319; https://doi.org/10.3390/nu17081319 - 10 Apr 2025
Viewed by 999
Abstract
Background: Water polo (WP) is a high-intensity team sport that requires a combination of physical endurance, muscular strength, speed, and specific technical skills. Due to the demanding and prolonged nature of this sport, adequate and balanced nutrition plays a fundamental role in athletes’ [...] Read more.
Background: Water polo (WP) is a high-intensity team sport that requires a combination of physical endurance, muscular strength, speed, and specific technical skills. Due to the demanding and prolonged nature of this sport, adequate and balanced nutrition plays a fundamental role in athletes’ performance, recovery, and overall health maintenance. Objectives: We aimed to compile all available information on the importance of ergonutrition and supplementation in the recovery of WP players. This will help in understanding this sport’s specific challenges and requirements, enabling players and coaches to design more effective recovery plans to optimize performance, achieve goals, and successfully cope with intense training and competition. Method: English-language publications were searched in databases such as Web of Science, Scopus, SciELO Citation Index, Medline (PubMed), KCI Korean Journal Database, and Current Contents Connect using a series of keywords such as WP, nutrition, recovery, and ergogenic aids individually or in combination. Results: In the field of ergonutritional recovery in WP, certain supplements such as whey protein, beta-alanine, L-arginine, spirulina, and copper can be beneficial for improving performance and recovery. In some cases, WP athletes may consider using ergogenic supplements to further improve their performance and recovery process. However, it is important to bear in mind that any supplement should be carefully evaluated under the supervision of a health professional or a sports nutritionist, as some supplements may present side effects or unwanted interactions. Conclusions: Adequate ergogenic nutrition adapted to the needs of WP players is essential not only to optimize their athletic performance but also to ensure effective recovery and maintain their long-term health and general well-being. The application of these strategies should be evidence-based and tailored to the individual needs of the players and the specific demands of the sport. Future experimental research that can confirm our results is essential. Full article
(This article belongs to the Special Issue New Strategies in Sport Nutrition: Enhancing Exercise Performance)
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18 pages, 1016 KiB  
Article
Can ChatGPT AI Replace or Contribute to Experts’ Diagnosis for Renovation Measures Identification?
by Juan Maria Hidalgo-Betanzos, Irati Prol-Godoy, Jon Terés-Zubiaga, Raúl Briones-Llorente and Alexander Martín-Garín
Buildings 2025, 15(3), 421; https://doi.org/10.3390/buildings15030421 - 28 Jan 2025
Viewed by 1437
Abstract
Building energy renovations demand expertise from professionals to guide processes, including diagnostics, project planning, interventions, and maintenance. The emergence of open-access AI, like ChatGPT in November 2022, offers new possibilities for improving these processes by assisting or potentially replacing human experts. This study [...] Read more.
Building energy renovations demand expertise from professionals to guide processes, including diagnostics, project planning, interventions, and maintenance. The emergence of open-access AI, like ChatGPT in November 2022, offers new possibilities for improving these processes by assisting or potentially replacing human experts. This study explores the effectiveness of ChatGPT in diagnosing energy renovation measures. Initial assessments involve basic queries to the AI, followed by the inclusion of additional data and secondary questions to gauge its full diagnostic potential. An existing building case from the literature is given to the AI to define the best energy renovation measures. Expert evaluations and comparisons with research-backed solutions assess the AI’s performance using different degrees of questioning details over 60 repetitions. The results indicate that ChatGPT can provide valuable insights and generate comprehensive lists of feasible measures and preliminary cost calculations and payback, but, in general, it lacks depth and quality without specialized input and preparation. A significant quality improvement was found between the tests with 2023 and 2024 AI versions. Open-access AI proves capable of enhancing renovation diagnostics but remains a complement rather than a replacement for building renovation expert judgment. This research underscores the potential of mainstream AI to democratize access to knowledge, albeit with limitations tied to its dependence on quality inputs and contextual expertise. Full article
(This article belongs to the Special Issue Selected Papers from the REHABEND 2024 Congress)
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38 pages, 2535 KiB  
Review
Endurance in Long-Distance Swimming and the Use of Nutritional Aids
by Álvaro Miguel-Ortega, Julio Calleja-González and Juan Mielgo-Ayuso
Nutrients 2024, 16(22), 3949; https://doi.org/10.3390/nu16223949 - 19 Nov 2024
Cited by 4 | Viewed by 5787
Abstract
Background: Long-distance swimmers exert energetic, physiological, and neuromuscular demands that must be matched with adequate body composition to improve their performance in long-distance swimming. Objectives: This review aims to compile all available information on energetic and physiological demands, optimal body composition, nutrition, and [...] Read more.
Background: Long-distance swimmers exert energetic, physiological, and neuromuscular demands that must be matched with adequate body composition to improve their performance in long-distance swimming. Objectives: This review aims to compile all available information on energetic and physiological demands, optimal body composition, nutrition, and ergogenic supplements in long-distance swimming. This will provide an understanding of the specific challenges and needs of this sport and will help swimmers and coaches design more effective training and nutrition plans to optimise performance and achieve their goals. Methods: Databases such as Web of Science, SciELO Citation Index, MEDLINE (PubMed), Current Contents Connect, KCI-Korean Journal Database, and Scopus were searched for publications in English using keywords such as swimming, endurance, energy demands, physiological demands, nutrition, body composition, and ergogenic aids, individually or in combination. Results: There is convincing evidence that several physical indicators, such as propulsive surface area, technical, such as stroke rate, and functional, such as hydration strategies, are related to swimming performance and body composition. Each athlete may have a specific optimal body fat level that is associated with improved sporting performance. The nutritional needs of open water swimmers during competition are quite different from those of pool swimmers. Conclusions: Swimmers with an adequate physique have a high body muscle mass and moderately related anaerobic strength both on land and in the water. These general and specific strength capacities, which are given by certain anthropometric and physiological characteristics, are seen throughout the work, as well as ergogenic and nutritional strategies, which have an important impact on long-distance swimming performance. Full article
(This article belongs to the Special Issue Dietary Supplements and Exercise Performance)
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15 pages, 7517 KiB  
Article
Different PSMA Radiopharmaceuticals: A Comparative Study of [18F]F-PSMA-1007, [18F]F-JK-PSMA-7, and [99mTc]Tc-PSMA-I&S in the Skeletal System
by Zsófia Sára Mikó, László Varga, István Farkas, Gyula Tóth, Kristóf Apró, Barnabás Márk Révész, Gábor Sipka, Péter Gergő Tompa, Annamária Bakos, Tamás Czékus, Mátyás Bukva, László Pávics, Linda Varga, Anikó Maráz and Zsuzsanna Besenyi
Pharmaceuticals 2024, 17(11), 1458; https://doi.org/10.3390/ph17111458 - 31 Oct 2024
Viewed by 1974
Abstract
Background: Numerous PSMA-based tracers are used for diagnostic prostate cancer imaging, but comprehensive comparisons between multiple ligands are lacking. This study aimed to compare physiological skeletal uptake and tracer uptake in commonly recommended PSMA reference regions across three different PSMA ligands in prostate [...] Read more.
Background: Numerous PSMA-based tracers are used for diagnostic prostate cancer imaging, but comprehensive comparisons between multiple ligands are lacking. This study aimed to compare physiological skeletal uptake and tracer uptake in commonly recommended PSMA reference regions across three different PSMA ligands in prostate cancer patients. Methods: A total of 281 prostate cancer patients were included. Using PET and SPECT imaging, target volumes of interest were defined via a semiautomatic method, and standardized uptake values (SUV) were calculated for the skeletal system and reference regions (liver, spleen, parotid gland, and blood pool). Results: Significant differences in SUV uptake were observed, with [18F]F-PSMA-1007 showing higher SUV values in the skeletal system. The parotid gland displayed the highest variability in uptake, while the blood pool and liver exhibited more homogeneous uptake across patients. Conclusions: While radioligands behave similarly in bone regions, there are notable differences in SUV patterns, particularly for PSMA-1007, which showed higher bone uptake. Parotid gland uptake variability suggests a reconsideration of its suitability as a reference region, while the liver, spleen, and blood pool showed more consistent uptake. During comparison, the technetium-labeled SPECT ligand proved as similarly effective as the two PET ligands for diagnostic imaging. Full article
(This article belongs to the Section Biopharmaceuticals)
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11 pages, 1898 KiB  
Article
Focal Unspecific Bone Uptake on [18F]PSMA-1007 PET: Evaluation Analog PROMISE Criteria and Validation via PET/CT Follow-Up
by Jonas-Alexander Benecke, Eduardo Calderón, Gerald Reischl, Andreas Brendlin, Igor Tsaur, Christian la Fougère and Jonas Vogel
Diagnostics 2024, 14(20), 2327; https://doi.org/10.3390/diagnostics14202327 - 18 Oct 2024
Cited by 1 | Viewed by 1894
Abstract
Background: Focal unspecific bone uptake (UBU) is common in [18F]PSMA-1007 PET/CT, yet its clinical significance remains unclear, causing uncertainty in treatment decisions. Material and Methods: We retrospectively analyzed 99 prostate cancer patients (age 69 ± 7) who underwent [18F]PSMA-1007 [...] Read more.
Background: Focal unspecific bone uptake (UBU) is common in [18F]PSMA-1007 PET/CT, yet its clinical significance remains unclear, causing uncertainty in treatment decisions. Material and Methods: We retrospectively analyzed 99 prostate cancer patients (age 69 ± 7) who underwent [18F]PSMA-1007 PET/CT scans (3 MBq/kg; uptake time 70 ± 14 min) for staging and follow-up (after 13.0 ± 7.2 months). Semiquantitative assessment using the miPSMA score, analogous to the PROMISE criteria, evaluated the prevalence of UBU and bone metastases. Results: In the initial PET/CT scan, 56 patients had 230 lesions classified as UBU. A total of 19 patients were found to have bone metastases and UBU, while 24 patients had no focal bone uptake. UBU distribution was as follows: ribs (50%), spine (30%), pelvis (15%), and other sites (5%). There were no significant differences in age, Gleason score, injected tracer dose, uptake time, SUVpeak of UBU, or SUVmean in the spleen and parotid gland between patients with and without UBU. Follow-up showed stable miPSMA-score and CT appearance in 44/56 patients with UBU (79%), minor changes in 5/56 patients (8%), and new bone metastases in 7/56 patients (12%). Patient-specific analysis indicated at least one bone metastasis initially classified as UBU in 3/56 patients (5%) and new bone metastases in 4/56 patients (7%). In total, 4 of the 24 patients (17%) without initial focal uptake developed osseous metastases at follow-up. Conclusions: No significant differences were found between patients with or without UBU. Only a small portion of UBU (2%) evolved into metastases, a lower rate than the development of new osseous metastases, which appears to be independent of UBU. Full article
(This article belongs to the Collection Nuclear Medicine and Molecular Imaging Technology)
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16 pages, 801 KiB  
Article
Interactions between Stress Levels and Hormonal Responses Related to Sports Performance in Pro Women’s Basketball Team
by Álvaro Miguel-Ortega, Julio Calleja-González and Juan Mielgo-Ayuso
J. Funct. Morphol. Kinesiol. 2024, 9(3), 133; https://doi.org/10.3390/jfmk9030133 - 31 Jul 2024
Cited by 2 | Viewed by 2292
Abstract
The testosterone to cortisol ratio (T:C ratio) is a measure of whether elite athletes are recovering from their training. This study described this hormone balance stress in elite women’s basketball. (1) Objectives: to analyse the fluctuation of T:C ratio over a 16-week period [...] Read more.
The testosterone to cortisol ratio (T:C ratio) is a measure of whether elite athletes are recovering from their training. This study described this hormone balance stress in elite women’s basketball. (1) Objectives: to analyse the fluctuation of T:C ratio over a 16-week period and explore itis relation to their athletic performance. The participants characteristics were: (height: 177.6 ± 6.4 cm; body mass: 77.808 ± 12.396 kg age: 26.0 ± 5.9 years; and a playing experience of 14.7 ± 2.9 years with 5.0 ± 1.2 years at the elite level. The T:C ratio at Time 1 is: 4.0 ± 2.4 (n = 12); and at Time 2 is: 5.1 ± 4.3 (n = 12). (2) Methods: during 16 weeks of competition, participants underwent analysis of blood samples to assess various biochemical parameters including hormone levels. In addition, their athletic performance was assessed with the following tests: jumping (SJ, CMJ, ABK, DJ); throwing test with a medicine ball (3 kg); Illinois COD agility test; sprint repeatability with change of direction; 20-m speed test without change of direction; and Yo-yo intermittent endurance test IET (II). (3) Results: The main alterations observed were an increase in T levels (1.687%) and a decrease in C levels (−7.634%) between moments, with an improvement (26.366%) in the T:C ratio. Improvements were also observed in some of the tests developed, such as jumping (SJ: 11.5%, p = 0.029; CMJ: 10.5%, p = 0.03; DJ: 13.0%, p = 0.01), upper body strength (MBT: 5.4%, p = 0.03), translation ability (20 m: −1.7%), repeated sprint ability (RSA: −2.2%), as well as intermittent endurance test (Yy (IET): 63.5%, p = 0.01), with significant changes in some of the performance tests. (4) Conclusions: T:C ratio may differ in a manner unrelated to training volume, showing some variation. These results may be attributed to the accumulation of psychophysiological stress during the season. Full article
(This article belongs to the Special Issue Health and Performance through Sports at All Ages 3.0)
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13 pages, 480 KiB  
Article
“Empowerment for Us by Us (E4UBU)”: Developing a Model of Empowerment Using Feminist Participatory Methods with LBQT+ Persons Assigned Female at Birth in Western Kenya
by Heather M. Tucker, Rebecca Odhiambo, Laura Jadwin-Cakmak, Anita Mbanda, Ashley Lacombe-Duncan, Caroline Rucah, Ini-Abasi Ubong, Cynthia Akoth Ouko, Wilson Odero and Gary W. Harper
Int. J. Environ. Res. Public Health 2024, 21(7), 948; https://doi.org/10.3390/ijerph21070948 - 19 Jul 2024
Cited by 2 | Viewed by 1945
Abstract
Lesbian, bisexual, queer, trans and other gender diverse persons assigned female at birth (heretofore referred to as “LBQT+ persons”) in Western Kenya experience intersectional oppression and stigma. This stigma can manifest in acts of sexual and gender-based violence (SGBV) and sexual and gender [...] Read more.
Lesbian, bisexual, queer, trans and other gender diverse persons assigned female at birth (heretofore referred to as “LBQT+ persons”) in Western Kenya experience intersectional oppression and stigma. This stigma can manifest in acts of sexual and gender-based violence (SGBV) and sexual and gender minority (SGM)-based violence, as well as various forms of discrimination—all of which have been linked to disproportionately higher levels of negative health outcomes for this group. Despite these challenges, many LBQT+ persons have been able to gain personal and collective power and thrive in this oppressive environment. The Empowerment for Us by Us (E4UBU) project is a mixed methods feminist participatory research study focused on exploring how LBQT+ persons conceptualize and define empowerment for themselves, and to understand their perspectives on how feelings of power and powerlessness influence their physical and mental health. This paper focuses on data from the first phase of the study, in which qualitative in-depth interviews were conducted with 40 LBQT+ persons (ages 19 to 50) from Kisumu and Homa Bay in Western Kenya. A participatory interpretive phenomenological analysis was conducted to understand the lived experiences of LBQT+ persons as they navigate intersectional oppression and its influence on their experiences of empowerment and subsequent health outcomes. Findings from this analysis were presented to two different focus groups composed of participants who had participated in the in-depth interviews to gather their insights on the interpretations of the interviews as a form of member checking. Findings revealed that “empowerment” was not experienced and viewed by LBQT+ persons as a monolithic construct, but rather a process through which LBQT+ persons are able to transform negative forces of intersectional oppression and powerlessness into experiences of power and subsequent individual and collective action and impact—all leading to improved mental health and well-being. This process is facilitated at several junctures by participatory seeking and attainment of community-appropriate resources at multiple socio-ecological levels that, when accessed with sufficient intensity, frequency, and duration, enhance one’s journey through the process of empowerment. These facilitation junctures are viewed as likely points of focus for public health intervention. Analysis also revealed that the process of empowerment is dependent on the context within which the process is occurring, the specific issues being faced, and the population of focus. Recommendations for how this model can be used for future research and practice to improve the lives of LBQT+ persons in Kenya are discussed. Full article
(This article belongs to the Special Issue Advancing Health Equity for Sexual and Gender Minority Populations)
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25 pages, 14797 KiB  
Article
Comparative Analysis of Metaheuristic Optimization Methods for Trajectory Generation of Automated Guided Vehicles
by Eduardo Bayona, Jesús Enrique Sierra-García and Matilde Santos
Electronics 2024, 13(4), 728; https://doi.org/10.3390/electronics13040728 - 11 Feb 2024
Cited by 1 | Viewed by 2236
Abstract
This paper presents a comparative analysis of several metaheuristic optimization methods for generating trajectories of automated guided vehicles, which commonly operate in industrial environments. The goal is to address the challenge of efficient path planning for mobile robots, taking into account the specific [...] Read more.
This paper presents a comparative analysis of several metaheuristic optimization methods for generating trajectories of automated guided vehicles, which commonly operate in industrial environments. The goal is to address the challenge of efficient path planning for mobile robots, taking into account the specific capabilities and mobility limitations inherent to automated guided vehicles. To do this, three optimization techniques are compared: genetic algorithms, particle swarm optimization and pattern search. The findings of this study reveal the different efficiency of these trajectory optimization approaches. This comprehensive research shows the strengths and weaknesses of various optimization methods and offers valuable information for optimizing the trajectories of industrial vehicles using geometric occupancy maps. Full article
(This article belongs to the Special Issue Intelligent Control of Unmanned Vehicles)
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19 pages, 9826 KiB  
Article
Evaluation of Prebiotic Potential of Crude Polysaccharides Extracted from Wild Lentinus polychrous and Lentinus squarrosulus and Their Application for a Formulation of a Novel Lyophilized Synbiotic
by Marutpong Panya, Chamraj Kaewraemruaen, Phairo Saenwang and Patcharin Pimboon
Foods 2024, 13(2), 287; https://doi.org/10.3390/foods13020287 - 16 Jan 2024
Cited by 4 | Viewed by 3315
Abstract
Edible mushrooms, including wild mushrooms, are currently being investigated as natural sources to evaluate their prebiotic potential. This study aimed to evaluate the prebiotic potential of crude polysaccharides (CPSs) extracted from wild Lentinus squarrosulus UBU_LS1 and Lentinus polychrous UBU_LP2 and their application as [...] Read more.
Edible mushrooms, including wild mushrooms, are currently being investigated as natural sources to evaluate their prebiotic potential. This study aimed to evaluate the prebiotic potential of crude polysaccharides (CPSs) extracted from wild Lentinus squarrosulus UBU_LS1 and Lentinus polychrous UBU_LP2 and their application as cryoprotectants in the freeze-drying process to formulate a novel synbiotic product. Based on fruiting body morphology and molecular identification, two wild edible mushrooms named UBU_LS1 and UBU_LP2 were identified as Lentinus squarrosulus and Lentinus polychrous, respectively. L. squarrosulus UBU_LS1 and L. polychrous UBU_LP2 contained high amounts of CPS after hot water extraction. Monosaccharide component analysis showed that CPS_UBU_LS1 and CPS_UBU_LP2 were typical heteropolysaccharides. CPS_UBU_LS1 and CPS_UBU_LP2 showed hydrolysis tolerance to the simulated human gastric acidic pH solution, indicating that these CPSs are capable of reaching the lower gastrointestinal tract. Antioxidant activity determined using the 1,1-diphenyl-2-picrylhydrazyl assay revealed that the CPS_UBU_LS1 and CPS_UBU_LP2 displayed greater antioxidant activity comparable with that of ascorbic acid. It was found that CPS_UBU_LS1 and CPS_UBU_LP2 have a high potential for stimulating growth in all probiotic strains. Moreover, both CPS compounds could possibly be used as cryoprotectants in freeze drying, since the viability of the selected probiotic L. fermentum 47-7 exhibited cell survival of greater than 70% after 90 days of storage at 4 °C. These results highlight that wild edible mushrooms L. squarrosulus UBU_LS1 and L. polychrous UBU_LP2 are potential natural sources of prebiotics and can be applied as cryoprotectants in the freeze-drying process. The crude polysaccharide derived from this study could also be considered as a potent antioxidative compound. Therefore, our study provides evidence to support the application of CPSs from wild edible mushrooms in synbiotic product development and in various functional foods. Finally, further evaluation of these prebiotics, including the determination of the potential rehabilitation of beneficial gut microbes in diseased individuals, is currently being conducted by our research group. Full article
(This article belongs to the Section Nutraceuticals, Functional Foods, and Novel Foods)
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14 pages, 1431 KiB  
Review
PSMA PET/CT in Castration-Resistant Prostate Cancer: Myth or Reality?
by Luca Urso, Luca Filippi, Angelo Castello, Maria Cristina Marzola, Mirco Bartolomei, Corrado Cittanti, Luigia Florimonte, Massimo Castellani, Paolo Zucali, Alessio Bruni, Roberto Sabbatini, Massimo Dominici, Stefano Panareo and Laura Evangelista
J. Clin. Med. 2023, 12(22), 7130; https://doi.org/10.3390/jcm12227130 - 16 Nov 2023
Cited by 12 | Viewed by 2821
Abstract
Background: prostate-specific membrane antigen (PSMA) ligand PET has been recently incorporated into international guidelines for several different indications in prostate cancer (PCa) patients. However, there are still some open questions regarding the role of PSMA ligand PET in castration-resistant prostate cancer (CRPC). The [...] Read more.
Background: prostate-specific membrane antigen (PSMA) ligand PET has been recently incorporated into international guidelines for several different indications in prostate cancer (PCa) patients. However, there are still some open questions regarding the role of PSMA ligand PET in castration-resistant prostate cancer (CRPC). The aim of this work is to assess the clinical value of PSMA ligand PET/CT in patients with CRPC. Results: PSMA ligand PET has demonstrated higher detection rates in comparison to conventional imaging and allows for a significant reduction in the number of M0 CRPC patients. However, its real impact on patients’ prognosis is still an open question. Moreover, in CRPC patients, PSMA ligand PET presents some sensitivity and specificity limitations. Due to its heterogeneity, CRPC may present a mosaic of neoplastic clones, some of which could be PSMA−/FDG+, or vice versa. Likewise, unspecific bone uptake (UBU) and second primary neoplasms (SNPs) overexpressing PSMA in the neoangiogenic vessels represent potential specificity issues. Integrated multi-tracer imaging (PSMA ligand and [18F]FDG PET) together with a multidisciplinary discussion could allow for reaching the most accurate evaluation of each patient from a precision medicine point of view. Full article
(This article belongs to the Special Issue PET Imaging in the Evaluation of Cancer Treatment)
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17 pages, 2316 KiB  
Article
Stress Levels and Hormonal Coupling and Their Relationship with Sports Performance in an Elite Women’s Volleyball Team
by Álvaro Miguel-Ortega, Julen Fernández-Landa, Julio Calleja-González and Juan Mielgo-Ayuso
Appl. Sci. 2023, 13(20), 11126; https://doi.org/10.3390/app132011126 - 10 Oct 2023
Cited by 5 | Viewed by 2340
Abstract
The testosterone–cortisol ratio is a concept in human biology that refers to the balance between testosterone, the main anabolic steroid, and cortisol, another steroid hormone. The two hormones are said to be habitually positively “coupled”. Increases or decreases in testosterone tend to be [...] Read more.
The testosterone–cortisol ratio is a concept in human biology that refers to the balance between testosterone, the main anabolic steroid, and cortisol, another steroid hormone. The two hormones are said to be habitually positively “coupled”. Increases or decreases in testosterone tend to be associated with corresponding increases or decreases in cortisol, and vice versa. The present study explored hormone coupling and its relationship to stress levels in the sport performances of an elite women’s volleyball team. (1) Aim: to assess the testosterone–cortisol concentration dynamic over 16 weeks and its link to sport performance in elite female volleyball players (height: 1.8 ± 0.1 m; 24.2 ± 2.7 years; playing experience 15 ± 2.8 years; years played at elite level 4.2 ± 2.2; testosterone–cortisol index time 1: 3.9 vs. time 2: 4.3) (n = 11). (2) Methods: blood samples (hormones among other biochemical parameters) and sports performance measurements (aerobic and anaerobic power among other tests) were taken from members of an elite women’s volleyball team over 16 weeks of competition. (3) Results: female volleyball players showed patterns of hormonal change and adaptation to stress. (4) Conclusions: the current investigation demonstrated that elite female volleyball players have higher basal levels of testosterone and cortisol than normal healthy women. The impact of training and competition is clearly reflected in the levels of T. Cortisol levels increase at the beginning of training and remain elevated throughout the season, but without significant changes. Full article
(This article belongs to the Special Issue Advances in Sport Injury Prevention)
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19 pages, 1865 KiB  
Article
Comparison of Sports Performance and Kinanthropometric Profiles of Elite Female Basketball and Volleyball Players over the Course of a Competitive Season
by Álvaro Miguel-Ortega, Julio Calleja-González and Juan Mielgo-Ayuso
Appl. Sci. 2023, 13(14), 8267; https://doi.org/10.3390/app13148267 - 17 Jul 2023
Cited by 11 | Viewed by 2902
Abstract
In order to maximize sports performance of team sportswomen, knowledge of the player’s characteristics in terms of different aspects and at different times of the season is needed. While the anthropometric and physical characteristics of men’s sports teams have been extensively studied, research [...] Read more.
In order to maximize sports performance of team sportswomen, knowledge of the player’s characteristics in terms of different aspects and at different times of the season is needed. While the anthropometric and physical characteristics of men’s sports teams have been extensively studied, research on women’s basketball and volleyball is scarce. (1) Purpose: This study aims to contribute data about the anthropometric and physical characteristics of female basketball and volleyball players from elite women’s teams (age: 24.3 ± 2.7 years; playing experience: 14.825 ± 2.8 years) (n = 23) with a two-fold objective: (1) to describe and compare the anthropometric characteristics of these two disciplines; and (2) to identify possible differences in various parameters of sports performance depending on the discipline. (2) Methods: The anthropometric profile includes the measurements recommended by the International Society for the Advancement of Kinanthropometry; the performance tests described aerobic and anaerobic power exercises. (3) Results: The overall somatotype of the players was moderate mesomorphic and low endomorphic (5.107–3.046–1.883). Statistical differences were found between the improvement of the physical performance level of female basketball players (77%) and female volleyball players (10%) from the first to the last measurement, with better results in most of the performance tests (p < 0.05). The sum of skinfolds was higher in female basketball players (p > 0.05). The percentage of fat-free mass correlated with improvements in lower body strength. (4) Conclusion: Lean body mass is an important predictor of exercise performance intensity. Excess fat mass is detrimental to the development of strength and endurance. Full article
(This article belongs to the Special Issue Advances in Physical Exercise and Wellbeing)
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19 pages, 618 KiB  
Article
Unintended Pedagogical Consequences of Emergency Remote Teaching at a Rural-Based University in South Africa
by Siyabonga Theophillus Pika and Sarasvathie Reddy
Educ. Sci. 2022, 12(11), 830; https://doi.org/10.3390/educsci12110830 - 17 Nov 2022
Cited by 2 | Viewed by 3003
Abstract
In this empirical article, we argue that while emergency remote teaching (ERT) may have achieved its goal of saving the academic years during the COVID-19 pandemic, it also constructed unintended pedagogical consequences that were possibly overlooked at the time of advocating for it. [...] Read more.
In this empirical article, we argue that while emergency remote teaching (ERT) may have achieved its goal of saving the academic years during the COVID-19 pandemic, it also constructed unintended pedagogical consequences that were possibly overlooked at the time of advocating for it. We also contend that students and lecturers from rural-based universities (RBUs) in South Africa experienced different unintended pedagogical consequences compared to their counterparts who belong to urban-based universities (UBUs). Thus, the research question that the article raises is as follows: What were the unintended pedagogical consequences that students and lecturers based at RBUs experienced during the transition to ERT? Drawing on students’ and lecturers’ lived experiences of ERT, this article foregrounds unintended pedagogical consequences that arose at one RBU in South Africa during the transition from face-to-face teaching to ERT. Underpinned by the tenets of critical realism philosophy, as well as student integration theory, in-depth interviews with three lecturers and six students were conducted. The findings of the study indicate that home conditions, individual characteristics, pre-COVID-19 blended learning experiences, university training and support, teaching, learning, assessment practices, and policies altogether contributed to the construction of unintended pedagogical consequences of ERT presented in this article. These consequences include (1) the exclusion of low-income students from active teaching and learning, (2) equipping middle-class students with better chances of success than working-class students, (3) distressing female students and lecturers more than their male counterparts, and (4) unproductive assessment practices. This study may be beneficial to academics and policymakers from similar contexts in their plight to continue with remote teaching and assessment (RTA) after the pandemic. Full article
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