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15 pages, 270 KB  
Article
Trade Openness, Foreign Direct Investment and Industrial Growth: Panel Data Evidence from the ASEAN Region
by Muhammad Tahir, Adam Abdullah, Abdulrahman A. Albahouth and Umar Burki
Economies 2026, 14(2), 48; https://doi.org/10.3390/economies14020048 - 6 Feb 2026
Viewed by 385
Abstract
This paper re-examines the role of trade and FDI inflows in accelerating the process of industrial growth involving countries belonging to the “Association of Southeast Asian Nations (ASEAN)” region. Trade openness and foreign direct investment (FDI) have improved the growth performance of numerous [...] Read more.
This paper re-examines the role of trade and FDI inflows in accelerating the process of industrial growth involving countries belonging to the “Association of Southeast Asian Nations (ASEAN)” region. Trade openness and foreign direct investment (FDI) have improved the growth performance of numerous economies and regions over the years. However, the specific role of both trade openness and FDI inflows in advancing the industrial growth process of economies has yet to be investigated in the case of economies belonging to ASEAN. This study analyzes data from 2000 to 2023 and employs several relevant econometric tools, including the “Pooled Ordinary Least Squares (POLS)”, “Fixed Effects Filter (FEF)”, “Feasible Generalized Least Squares (FGLS)” and “Two Stages Least Squares (TSLS)”, to assess the specific impact of both trade openness and FDI inflows on industrial growth. Our findings show that both trade openness and FDI have advanced the industrial growth of ASEAN member economies. In terms of relative importance, the impact of trade openness is higher as compared to FDI inflows on the industrial sector. Similarly, the results demonstrate that the industrial growth of ASEAN economies could be explained positively by increased domestic investment and government expenditures. Moreover, our results indicate that the inflation rate and the natural resource sector have adversely impacted industrial growth. Finally, the labor force has not had the desirable positive impact on the industrial progress of ASEAN economies. The obtained results are robust across alternative specifications and estimation techniques. Therefore, our results have important policy implications for ASEAN economies. Full article
(This article belongs to the Section International, Regional, and Transportation Economics)
21 pages, 2923 KB  
Article
Enhancing the Signature Rose Aroma of Kluyveromyces marxianus-Fermented Milk Beer via Adaptive Laboratory Evolution
by Chen Xing, Youming Tan, Xinchi Jiang, Wenlu Li, Qihao Wang, Zihao Liu, Hong Zeng and Yanbo Wang
Foods 2026, 15(2), 229; https://doi.org/10.3390/foods15020229 - 8 Jan 2026
Viewed by 422
Abstract
Milk beer, a modern Chinese dairy beverage, is usually fermented by the co-culture of lactic acid bacteria (LAB) and Kluyveromyces marxianus (K. marxianus), with the latter known for its ability to produce aroma compounds. However, the accumulation of lactic acid produced [...] Read more.
Milk beer, a modern Chinese dairy beverage, is usually fermented by the co-culture of lactic acid bacteria (LAB) and Kluyveromyces marxianus (K. marxianus), with the latter known for its ability to produce aroma compounds. However, the accumulation of lactic acid produced by LAB can inhibit the growth of K. marxianus, which inevitably hinders the diversity and intensity of flavor compounds in milk beer. In this study, adaptive laboratory evolution (ALE) was applied to the parental strain Kluyveromyces marxianus CICC1953 (Km-P) under different concentrations of lactic acid to obtain an evolved strain Km-ALE-X20 with enhanced acid tolerance and increased titer of phenylethyl alcohol, which has a floral, rose-like aroma. Km-ALE-X20 demonstrated a 16-fold increase in OD600 and a 28-fold increase in phenylethyl alcohol production compared with Km-P in chemically defined medium (CDM) containing 20 g/L lactic acid. Comparative genomics analysis suggested that mutated genes CTA1, TSL1, ERG2 were related to enhanced acid tolerance, while ARO8, ARO9, FKS2 were related to increased production of aroma compounds. Furthermore, Km-ALE-X20-fermented milk beer showed 33.87% and 32.43% higher production in alcohol and ester compounds than that of Km-P-fermented milk beer. Interestingly, sensory analysis showed that while Km-ALE-X20-fermented milk beer had higher sensory scores for rose and fruity aroma attributes, Km-P-fermented milk beer possessed a more balanced aroma profile. This paper highlights the first application of ALE to enhance the signature rose aroma of K. marxianus-fermented milk beer and provides an efficient framework for ALE-based breeding of aroma-producing food microorganisms. Full article
(This article belongs to the Section Food Microbiology)
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20 pages, 422 KB  
Article
Institutional Stimulants for Low-Carbon Transport: The Case of the Fleet Electrification in the Polish Logistics Industry
by Anna Wronka, Marta Raźniewska, Agata Rudnicka and Grażyna Kędzia
Energies 2025, 18(23), 6339; https://doi.org/10.3390/en18236339 - 2 Dec 2025
Cited by 1 | Viewed by 384
Abstract
The aim of the paper is to recognize the role of external institutions in supporting the Transport, Shipping, and Logistics (TSL) sector in the transformation towards sustainable and low-emission operations in Poland. In the context of the EU’s decarbonization agenda and accelerating climate [...] Read more.
The aim of the paper is to recognize the role of external institutions in supporting the Transport, Shipping, and Logistics (TSL) sector in the transformation towards sustainable and low-emission operations in Poland. In the context of the EU’s decarbonization agenda and accelerating climate challenges, the study explores how regulatory, financial, and normative mechanisms affect the electrification of transport fleets. A mixed-methods approach was applied, combining qualitative content analysis of European and national policy frameworks with a quantitative CATI survey among logistics enterprises. The results reveal that legal and normative instruments remain the dominant institutional drivers of fleet electrification, while fiscal incentives—subsidies and tax reliefs—play a supportive but still secondary role. Sectoral and financial pressures from banks and market stakeholders are emerging as new, complementary forces of change. Firm size, ownership structure, and market scope significantly moderate these perceptions. The paper contributes to institutional and innovation-diffusion theory and offers policy insights for designing coherent and multi-level frameworks. Full article
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13 pages, 944 KB  
Article
Phytochemical Screening by HRLC–MS/MS (Q-TOF) and Antioxidant and Anti-Inflammatory Properties of Thottea sivarajanii Leaf Extract
by Pooja Mohan Padmalayam, Aswathi Moothakoottil Kuttithodi, Alby Tom, Joice Tom Job, Satheesh George and Arunaksharan Narayanankutty
Pharmaceuticals 2025, 18(12), 1794; https://doi.org/10.3390/ph18121794 - 25 Nov 2025
Viewed by 772
Abstract
Background: Numerous degenerative diseases are brought on by inflammation and oxidative stress. Metabolites from plants contain anti-inflammatory and antioxidant properties. Indigenous and understudied, Thottea sivarajanii is a significant ethnobotanical herb. It is native to the Western Ghats and belongs to the Aristolochiaceae [...] Read more.
Background: Numerous degenerative diseases are brought on by inflammation and oxidative stress. Metabolites from plants contain anti-inflammatory and antioxidant properties. Indigenous and understudied, Thottea sivarajanii is a significant ethnobotanical herb. It is native to the Western Ghats and belongs to the Aristolochiaceae family. Objectives: The current study investigated the antioxidant and anti-inflammatory properties of T. sivarajanii leaf methanol extract (TSL) and the insights provided by phytochemical analysis. Methods: The HRLC–MS/MS (Q-TOF) study is used for the phytochemical analysis. The antioxidant efficacy is evaluated in terms of DPPH and ABTS radical scavenging, and reducing power (FRAP assay). In vitro anti-inflammatory efficacy was evaluated on RAW 264.7 cells challenged with lipopolysaccharide (LPS). Result: The HRLC–MS/MS (Q-TOF) study indicated the presence of bioactive molecules such as ursolic acid, Daidzein 4’,7-diglucoside, Calophyllin B, and Berbamine, etc. The results showed in vitro antioxidant capacity in DPPH, and ABTS, radical scavenging, and ferric-reducing activities with respective IC50 and EC50 values of 184.5 ± 2.4, 24.15 ± 0.13, and 4.94 ± 0.32 µg/mL, respectively. LPS significantly stimulated the production of IL-1β, IL-6, and TNF-α in RAW 264.7 cells (p < 0.001). Treatment with TSL reduced levels of IL-1β and IL-6 from 776.1 ± 11.4 and 1678.1 ± 12.4 to 195.4 ± 9.2 and 465.4 ± 11.8 pg/mg protein. It also reduced NO levels from 91.4 ± 1.3 to 30.8 ± 1.7 µM/mg protein while reducing TNF-α levels from 2041.2 ± 15.1 to 1037.5 ± 15.4 pg/mg protein. Conclusions: This work contributes to the growing evidence supporting the pharmacological importance of the underexplored Thottea sivarajanii, highlighting this species as a promising candidate for natural antioxidant and anti-inflammatory agents. Full article
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20 pages, 4835 KB  
Article
An Asymmetric SiC Power Module Directly Integrated with Vapor Chamber for Thermal Balancing in MMC
by Binyu Wang, Xiwei Zhou, Yawen Zhu, Mengfei Qi, Hai Lin, Bobin Yao, Shaohua Huang, Xuetao Wang, Qisheng Wu and Weiyu Liu
Appl. Sci. 2025, 15(20), 10869; https://doi.org/10.3390/app152010869 - 10 Oct 2025
Viewed by 1133
Abstract
Power modules in silicon carbide (SiC)-based modular multilevel converters (MMCs) suffer from notably severe thermal imbalance and localized overheating. This paper puts forward an asymmetric SiC power module with direct integration of a vapor chamber (VC), designed to balance the thermal distribution inside [...] Read more.
Power modules in silicon carbide (SiC)-based modular multilevel converters (MMCs) suffer from notably severe thermal imbalance and localized overheating. This paper puts forward an asymmetric SiC power module with direct integration of a vapor chamber (VC), designed to balance the thermal distribution inside MMC SMs. Specifically, the chips on the lower side of the HBSM are soldered onto a VC, which is additionally mounted on the direct bonding copper (DBC). Endowed with merits such as favorable temperature uniformity, exceptional thermal conductivity, compact size, flexible design, high integration level, and reasonable cost, the VC serves as an outstanding heat diffuser significantly expanding the effective thermal conduction area and reducing thermal resistance. Moreover, in this structure, the VC also functions as a conductor for device current. Finite element method (FEM) simulation results reveal that the proposed structure can notably reduce the hotspot temperature (from 109 °C to 71.8 °C), the maximum temperature difference among chips (from 45 °C to 13.89 °C), and the low-frequency temperature swing (TSL) (from 68 °C to 38 °C). Consequently, the issues of localized overheating and thermal imbalance in SiC-MMC SMs are effectively addressed. Lifetime analysis further indicates that the proposed structure can reduce the annual damage rate of the chip solder layer by 92.6%. Full article
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21 pages, 1771 KB  
Article
Laboratory and Semi-Field Cage Demography Studies of Diachasmimorpha longicaudata Mass-Reared on Two Ceratitis capitata Strains
by Lorena Suárez, Segundo Ricardo Núñez-Campero, Silvia Lorena Carta Gadea, Fernando Murúa, Flávio Roberto Mello Garcia and Sergio Marcelo Ovruski
Insects 2025, 16(10), 1031; https://doi.org/10.3390/insects16101031 - 6 Oct 2025
Viewed by 1042
Abstract
Ceratitis capitata (Wiedemann) or medfly is a polyphagous pest of fruit crops worldwide. The Asian-native larval parasitoid Diachasmimorpha longicaudata (Ashmead) is mass-reared at the San Juan Biofactory and is currently released for medfly control in Argentina. Information on parasitoid survival, reproduction, and population [...] Read more.
Ceratitis capitata (Wiedemann) or medfly is a polyphagous pest of fruit crops worldwide. The Asian-native larval parasitoid Diachasmimorpha longicaudata (Ashmead) is mass-reared at the San Juan Biofactory and is currently released for medfly control in Argentina. Information on parasitoid survival, reproduction, and population growth parameters is critical for optimizing the mass-rearing process and successfully achieving large-scale release. This study provides a first-time insight into the demography of two population lines of D. longicaudata: one mass-reared on medfly larvae of the Vienna-8 temperature-sensitive lethal genetic sexing strain and the other on larvae of the wild biparental medfly strain. The aim was to compare both parasitoid populations to improve mass-rearing quality and to assess performance on medfly in a semi-arid environment, typical of Argentina’s central-western fruit-growing region. Tests were performed under laboratory and non-controlled environmental conditions in semi-field cages during three seasons. Dl(Cc-bip) females exhibited higher reproductive potential than did Dl(Cc-tsl) females under lab conditions. However, both Dl(Cc-bip) and Dl(Cc-tsl) were found to be similar high-quality females with high population growth rates in warm–temperate seasons, i.e., late spring and summer. Dl(Cc-bip) females were only able to sustain low reproductive rates in early autumn, a colder season. These results are useful for improving the parasitoid mass production at the San Juan Biofactory and redesigning parasitoid release schedules in Argentina’s irrigated, semi-arid, fruit-growing regions. Full article
(This article belongs to the Section Insect Pest and Vector Management)
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13 pages, 4502 KB  
Article
Wavelength Calibration for an External Cavity Diode Laser Using a Polynomial Dual-Cosine Model
by Suman Ai, Ruifeng Kan, Cheng Du, Zhongqiang Yu, Weiqi Xing, Dingfeng Shi, Chuge Chen, Rantong Niu, Zhenyu Xu and An Huang
Photonics 2025, 12(10), 964; https://doi.org/10.3390/photonics12100964 - 29 Sep 2025
Viewed by 501
Abstract
A polynomial dual-cosine model is proposed for the wavelength calibration of an ECDL (Santec-TSL710-O-band). An analysis of the ECDL’s measured spectral data demonstrates that the polynomial dual-cosine model reduces the relative wavenumber fitting residuals by a factor of five within a scanning range [...] Read more.
A polynomial dual-cosine model is proposed for the wavelength calibration of an ECDL (Santec-TSL710-O-band). An analysis of the ECDL’s measured spectral data demonstrates that the polynomial dual-cosine model reduces the relative wavenumber fitting residuals by a factor of five within a scanning range of 30 cm−1. The experimental results of broadband temperature measurement (700~1600 K) in the tube furnace confirm that the proposed model successfully reduces the maximum temperature relative error from 6.7% to 2.3%. The wavelength calibration model effectively promotes further research on the broadband absorption spectroscopy thermometry method and its application in the temperature diagnostics of aeroengine combustors. Full article
(This article belongs to the Special Issue Advancements in Optics and Laser Measurement)
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34 pages, 5186 KB  
Article
Techno-Economic and Life Cycle Assessments of Aqueous Phase Reforming for the Energetic Valorization of Winery Wastewaters
by Giulia Farnocchia, Carlos E. Gómez-Camacho, Giuseppe Pipitone, Roland Hischier, Raffaele Pirone and Samir Bensaid
Sustainability 2025, 17(17), 7856; https://doi.org/10.3390/su17177856 - 31 Aug 2025
Cited by 4 | Viewed by 1836
Abstract
Globally, winery wastewaters (WWWs) are estimated to account for about 62.5 billion L annually (2021), with COD levels up to 300,000 mg O2/L primarily attributed to residual ethanol, posing serious environmental concerns. Conventional treatments are effective in COD removal, but they [...] Read more.
Globally, winery wastewaters (WWWs) are estimated to account for about 62.5 billion L annually (2021), with COD levels up to 300,000 mg O2/L primarily attributed to residual ethanol, posing serious environmental concerns. Conventional treatments are effective in COD removal, but they often miss opportunities for energy recovery and resource valorization. This study investigates the aqueous phase reforming (APR) of ethanol-rich wastewater as an alternative treatment for both COD reduction and energy generation. Two scenarios were assessed: electricity and heat cogeneration (S1) and hydrogen production (S2). Process simulations in Aspen Plus® V14, based on lab-scale APR data, provided upscaled material and energy flows for techno-economic analysis, life cycle assessment, and energy sustainability analysis of a 2.5 m3/h plant. At 75% ethanol conversion, the minimum selling price (MSP) was USD0.80/kWh with a carbon footprint of 0.08 kg CO2-eq/kWh for S1 and USD7.00/kg with 2.57 kg CO2-eq/kg H2 for S2. Interestingly, S1 revealed a non-linear trade-off between APR performance and energy integration, with higher ethanol conversion leading to a higher electricity selling price because of the increased heat reactor duty. In both cases, the main contributors to global warming potential (GWP) were platinum extraction/recovery and residual COD treatment. Both scenarios achieved a positive energy balance, with an energy return on investment (EROI) of 1.57 for S1 and 2.71 for S2. This study demonstrates the potential of APR as a strategy for self-sufficient energy valorization and additional revenue generation in wine-producing regions. Full article
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15 pages, 5325 KB  
Article
Image-Tracking-Driven Symmetrical Steering Control with Long Short-Term Memory for Linear Charge-Coupled-Device-Based Two-Wheeled Self-Balancing Cart
by Yi-Jen Mon
Symmetry 2025, 17(5), 747; https://doi.org/10.3390/sym17050747 - 13 May 2025
Cited by 3 | Viewed by 775
Abstract
This paper presents a control framework for the image tracking of two-wheeled self-balancing carts, with the objective of achieving precise tracking control. Exploiting the remarkable memory capacity of the Long Short-Term Memory (LSTM) neural network for sequence signals, the framework conducts image memory [...] Read more.
This paper presents a control framework for the image tracking of two-wheeled self-balancing carts, with the objective of achieving precise tracking control. Exploiting the remarkable memory capacity of the Long Short-Term Memory (LSTM) neural network for sequence signals, the framework conducts image memory judgment and memorization, aiming to enhance control accuracy. After the training phase, comprehensive simulations and real-world experiments are carried out based on the established model to verify the effectiveness and practicality of the proposed control strategy. The system utilizes the TSL1401 linear array CCD lens to detect black tapes on the ground and identify and memorize surrounding images. Through the establishment of a continuous set of training sample points, the LSTM network is trained using Python and TensorFlow. This training process optimizes the network’s weights and generates weight files, which can be readily converted into machine code for physical implementation. Initially, the effectiveness of the control law is verified through simulating the symmetrical steering control of the two-wheeled cart. The simulation results demonstrate the validity of the proposed design method and its superior performance. Finally, a physical two-wheeled self-balancing cart is developed to further validate the feasibility of the framework. Experimental results confirm that this method is highly effective, demonstrating robust image tracking capabilities and optimal tracking performance. Full article
(This article belongs to the Special Issue Symmetry/Asymmetry in Fuzzy Control)
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13 pages, 10456 KB  
Article
Research on the Mechanical Properties and Modification Mechanisms of Orthogonal Optimization Composite Cement-Based Thin Spray On-Liner
by Diantao Zheng, Xinming Chen, Huazhe Jiao, Liuhua Yang, Xiaohui Liu, Yulong Han and Ziyang Liu
Materials 2025, 18(8), 1837; https://doi.org/10.3390/ma18081837 - 17 Apr 2025
Viewed by 673
Abstract
Thin spray on-liner (TSL) is a new type of rock support technology, but ordinary cement-based TSL has low tensile strength and poor toughness, which makes it difficult to meet the challenges of large deformation of coal mine roadway perimeter rock surface maintenance. A [...] Read more.
Thin spray on-liner (TSL) is a new type of rock support technology, but ordinary cement-based TSL has low tensile strength and poor toughness, which makes it difficult to meet the challenges of large deformation of coal mine roadway perimeter rock surface maintenance. A high-performance composite cement-based TSL was obtained by adding acrylic emulsion, basalt fiber and rubber powder to modify ordinary Portland cement. The orthogonal test and range analysis method were used to systematically study the change law of the physical and mechanical properties of the composite cement-based TSL, determine its reasonable ratio, and further microscopic analysis to find out the modification mechanism. The results show that the reasonable ratio of composite cement-based TSL is as follows: polymer–cement ratio is 1.75, basalt fiber content is 1%, and rubber powder content is 3%; that is, the viscosity is 20,000 mps, and the elongation, tensile strength and adhesive strength in 28 d are 121%, 2.28 Mpa, and 1.66 Mpa, respectively. When the acrylic emulsion-basalt fiber-rubber powder is compositely modified, the acrylic emulsion cures and the cement hydration product to form a three-dimensional space network structure, which increases the compactness, the basalt fiber reduces the porosity of the matrix, inhibits the development of matrix cracks, and the rubber powder improves the elongation of the matrix and jointly improves the mechanical properties of TSL. This study provides a theoretical basis for the preparation of composite cement-based TSL. Full article
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13 pages, 13487 KB  
Article
Microstructure and Cracking Behavior of a Four-Layer Thermal Barrier Coating After Thermal Cycle Test
by Xuyang Wang, Yanna Cui, Yang Zhou, Yuzhu Zhao and Jun Wang
Coatings 2025, 15(3), 307; https://doi.org/10.3390/coatings15030307 - 6 Mar 2025
Cited by 3 | Viewed by 1485
Abstract
Microstructure evolution and cracking behavior of a four-layer thermal barrier coating (TBC) with double YSZ layers during thermal cycle tests were studied in the current work. The temperature range of the thermal cycle test ranged from room temperature to 1100 °C under atmospheric [...] Read more.
Microstructure evolution and cracking behavior of a four-layer thermal barrier coating (TBC) with double YSZ layers during thermal cycle tests were studied in the current work. The temperature range of the thermal cycle test ranged from room temperature to 1100 °C under atmospheric conditions. The TBC consisted of tetragonal t′ and t phases as well as monoclinic yttrium oxide. After 500 thermal cycles, the m-ZrO2 phase was formed through the phase transformation from t′-ZrO2 to m-ZrO2 and c-ZrO2. A large number of bulk thermally grown oxides (TGO), including chromium, spinel, and yttrium aluminates, were formed around pores in the transition layer (TL). Furthermore, the thickness of the TGO layer increased with a relatively low increase rate during the test (where kp was about 0.17 μm2/h). This may be attributed to the formation of bulk TGO around pores within the TL, which could consume some of the oxygen. The results show that large horizontal cracks are likely to form at the TSL/TIL and TIL/TL interfaces, while vertical cracks tend to occur near the surface of the TSL, and the propagation rate is relatively low. The propagation of horizontal cracks is the primary cause of failure in this four-layer structure. After the thermal cycle test, the porosity of TSL decreased significantly, from 7.17% to 0.76%. The results in this study may help optimize the design and preparation of TBCs with double YSZ layers. Full article
(This article belongs to the Special Issue Advances of Ceramic and Alloy Coatings, 2nd Edition)
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18 pages, 1140 KB  
Article
Effect of Schinus areira L. Essential Oil on Attraction, Reproductive Behavior, and Survival of Ceratitis capitata Wiedemann
by Flavia Jofré Barud, María Pía Gomez, María Josefina Ruiz, Guillermo Bachmann, Diego Fernando Segura, María Teresa Vera and María Liza López
Plants 2025, 14(5), 794; https://doi.org/10.3390/plants14050794 - 4 Mar 2025
Viewed by 1179
Abstract
The essential oil (EO) of Schinus areira exhibits a chemical composition dominated by monoterpene and sesquiterpene hydrocarbons, with α-phellandrene, limonene, α-pinene, and p-cymene as major constituents. This study aimed to evaluate the effects of S. areira EO on the biology and behavior of [...] Read more.
The essential oil (EO) of Schinus areira exhibits a chemical composition dominated by monoterpene and sesquiterpene hydrocarbons, with α-phellandrene, limonene, α-pinene, and p-cymene as major constituents. This study aimed to evaluate the effects of S. areira EO on the biology and behavior of the Mediterranean fruit fly, Ceratitis capitata, particularly its attraction to the EO and the impact on its reproductive behavior and survival. Females were attracted at the initial choice and the time spent in the arm of the Y-tube olfactometer with the EO was longer, while males were attracted at the final choice, indicating the attractive potential of S. areira EO for both sexes of C. capitata. Within the context of the sterile insect technique (SIT), the better performance of released sterile males allows more copulations with wild females in competition with wild males, increasing the efficacy of the SIT. Exposure of tsl sterile males to the EO did not enhance their sexual competitiveness and increased latency to initiate copulation, indicating potential adverse effects. In addition, in oviposition assays, only a low concentration of the EO stimulated egg-laying on treated substrates, possibly due to the absence of deterrent compounds such as linalool. Finally, the LD50 of the EO was <25 µg/fly for both females and males, at 72 h post-treatment. These findings highlight the potential of EOs as biopesticides that influence the behaviors of C. capitata and emphasize the need for further studies to optimize their application in integrated pest management strategies, including the SIT. Full article
(This article belongs to the Special Issue Emerging Topics in Botanical Biopesticides—2nd Edition)
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11 pages, 816 KB  
Article
The Role of Interdisciplinary Convergence for Mental Health Among Korean Military Servicemen: Focusing on Depression and Salivary Dehydroepiandrosterone-Sulfate
by Daeyeon Jang and Wonjung Ryu
Healthcare 2025, 13(4), 424; https://doi.org/10.3390/healthcare13040424 - 15 Feb 2025
Cited by 1 | Viewed by 1480
Abstract
(1) Background/Objectives: The purpose of this study was to examine the effectiveness of the “Thank You, Sorry, Love” (TSL) program for improving relationships on mental health and hormones of military soldiers in Korea. (2) Methods: We focused on soldiers’ levels of depression and [...] Read more.
(1) Background/Objectives: The purpose of this study was to examine the effectiveness of the “Thank You, Sorry, Love” (TSL) program for improving relationships on mental health and hormones of military soldiers in Korea. (2) Methods: We focused on soldiers’ levels of depression and salivary DHEA-S. The effectiveness evaluation of the program used the pretest–posttest control group design, one of the Quasi-experimental design models. The program evaluation used a quasi-experimental design with a pre-test, post-test, and a follow-up for a treatment group and a control group. The sample comprised 40 military soldiers, who were divided into an experimental group (n = 20) receiving the TSL intervention and a control group (n = 20) without intervention. The study was conducted from June to September 2016, and the effectiveness of the intervention was evaluated through pre-test, post-test, and four-week follow-up tests. (3) Results: Our results revealed that soldiers’ depression and DHEA-S levels significantly differed between the two groups. During the analysis of the program’s effectiveness in which the pre-test was controlled, a statistically significant difference was found between the groups in the post-test (F = 12.666, p < 0.01, ES = 0.255) and the follow-up test (F (1, 39) = 13.319, p < 0.01, ES = 0.265) in DHEA-S. (4) Conclusions: These findings imply that the TSL program can be an effective intervention for soldiers suffering from depression while helping to produce clinical guidelines that could be made available in the field of military social work in Korea, which are still in their beginning stages. Full article
(This article belongs to the Topic Migration, Health and Equity)
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15 pages, 4867 KB  
Article
The Nature of High-Temperature Peaks of Thermally Stimulated Luminescence in NaCl:Li and KCl:Na Crystals
by Kuanyshbek Shunkeyev, Shynar Sagimbayeva, Adelya Kenzhebayeva and Zarina Serikkaliyeva
Crystals 2025, 15(1), 67; https://doi.org/10.3390/cryst15010067 - 12 Jan 2025
Cited by 3 | Viewed by 1657
Abstract
For the first time, thermally stimulated luminescence spectra in the region of high-temperature peaks (up to 770 K) have been measured in NaCl:Li and KCl:Na single crystals (with impurity cations of small ionic radii) exposed to isodose irradiation by X-rays irradiated uniformly. Comparative [...] Read more.
For the first time, thermally stimulated luminescence spectra in the region of high-temperature peaks (up to 770 K) have been measured in NaCl:Li and KCl:Na single crystals (with impurity cations of small ionic radii) exposed to isodose irradiation by X-rays irradiated uniformly. Comparative analysis of these spectra with the spectra of X-ray and tunnel luminescence of the same crystals showed that the luminescence associated with exciton-like formations near impurity cations dominates in all three cases. The formation mechanisms of such bound excitons during a thermal dissociation of complex radiation defects are considered. Integral light sums of high-temperature TSL in NaCl:Li and KCl:Na crystals are significantly higher than that of a standard LiF:Mg, Ti dosimetric crystal (a TLD-100 luminescent dosimeter). Full article
(This article belongs to the Section Inorganic Crystalline Materials)
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16 pages, 4190 KB  
Article
Oligo(ethylene glycol) Methacrylate Copolymer-Modified Liposomes for Temperature-Responsive Drug Delivery System
by Maria Isabel Martinez Espinoza, Sezen Gül, Luisa Mugnaini and Francesco Cellesi
Molecules 2024, 29(23), 5511; https://doi.org/10.3390/molecules29235511 - 21 Nov 2024
Cited by 1 | Viewed by 1550
Abstract
A thermoresponsive copolymer based on oligo(ethylene glycol) methacrylate, Chol-P(MEO2MA-co-OEGMA), was synthesized using Atom Transfer Radical Polymerization (ATRP) and incorporated into thermosensitive liposomes (TSLs) for controlled drug release. The copolymer exhibited a lower critical solution temperature (LCST) of 37 °C, making it [...] Read more.
A thermoresponsive copolymer based on oligo(ethylene glycol) methacrylate, Chol-P(MEO2MA-co-OEGMA), was synthesized using Atom Transfer Radical Polymerization (ATRP) and incorporated into thermosensitive liposomes (TSLs) for controlled drug release. The copolymer exhibited a lower critical solution temperature (LCST) of 37 °C, making it suitable for biomedical applications requiring precise thermal triggers. The copolymer was incorporated into various TSL formulations alongside phospholipids such as DPPC, Lyso-PC, HSPC, and DSPC. Physicochemical characterization of the liposomes, including average size, polydispersity index, loading efficiency (LE), and encapsulation efficiency (EE), was performed using dynamic light scattering and fluorescence spectroscopy. The results showed that the incorporation of the copolymer slightly affected particle size and decreased LE and EE in most formulations. Lyso-PC-containing formulations exhibited lower LE and EE, likely due to instability during purification. Albumin encapsulation demonstrated lower LE compared to the smaller carboxyfluorescein drug model, highlighting the influence of molecular weight on loading. Although copolymer-modified liposomes showed reduced loading capacity, they enhanced thermoresponsiveness in HSPC-based formulations. These findings suggest that incorporating thermoresponsive polymers into TSLs can optimize drug delivery systems for targeted, thermally triggered release. Full article
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