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90 Results Found

  • Article
  • Open Access
2 Citations
1,358 Views
21 Pages

Genome-Wide Identification and Expression Profiling of the SPL Transcription Factor Family in Response to Abiotic Stress in Centipedegrass

  • Dandan Kong,
  • Maotao Xu,
  • Siyu Liu,
  • Tianqi Liu,
  • Boyang Liu,
  • Xiaoyun Wang,
  • Zhixiao Dong,
  • Xiao Ma,
  • Junming Zhao and
  • Xiong Lei

28 December 2024

SQUAMOSA promoter-binding protein-like (SPL) transcription factors play a critical role in the regulation of gene expression and are indispensable in orchestrating plant growth and development while also improving resistance to environmental stressor...

  • Article
  • Open Access
21 Citations
3,787 Views
16 Pages

Genome-Wide Identification of the SQUAMOSA Promoter-Binding Protein-like (SPL) Transcription Factor Family in Sweet Cherry Fruit

  • Yueting Sun,
  • Yanyan Wang,
  • Yuqin Xiao,
  • Xiang Zhang,
  • Bingyang Du,
  • Maihemuti Turupu,
  • Chao Wang,
  • Qisheng Yao,
  • Shilin Gai and
  • Tianhong Li
  • + 2 authors

2 February 2023

Plant-specific SQUAMOSA promoter-binding protein-like (SPL) transcription factors play important regulatory roles during plant growth and development, fruit ripening, inflorescence branching, and biotic and abiotic stresses. However, there have been...

  • Article
  • Open Access
7 Citations
3,710 Views
13 Pages

20 July 2021

Squamosa promoter-binding protein-like (SPL) is a major family of plant-specific transcription factor, which is involved in multiple biological processes, such as plant growth and development, hormone response, light response and stress response. The...

  • Article
  • Open Access
9 Citations
2,557 Views
19 Pages

Genome-Wide Identification and Expression Analysis of the SQUAMOSA Promoter-Binding Protein-like (SPL) Transcription Factor Family in Catalpa bungei

  • Erqin Fan,
  • Caixia Liu,
  • Zhi Wang,
  • Shanshan Wang,
  • Wenjun Ma,
  • Nan Lu,
  • Yuhang Liu,
  • Pengyue Fu,
  • Rui Wang and
  • Junhui Wang
  • + 2 authors

As a plant-specific transcription factor, the SPL gene family plays a critical role in plant growth and development. Although the SPL gene family has been identified in diverse plant species, there have been no genome-wide identification or systemati...

  • Article
  • Open Access
20 Citations
4,274 Views
23 Pages

11 March 2020

SPL (SQUAMOSA promoter binding protein-like) gene family is specific transcription factor in the plant that have an important function for plant growth and development. Although the SPL gene family has been widely studied and reported in many various...

  • Article
  • Open Access
31 Citations
3,339 Views
16 Pages

The Role of EjSPL3, EjSPL4, EjSPL5, and EjSPL9 in Regulating Flowering in Loquat (Eriobotrya japonica Lindl.)

  • Yuanyuan Jiang,
  • Jiangrong Peng,
  • Man Wang,
  • Wenbing Su,
  • Xiaoqing Gan,
  • Yi Jing,
  • Xianghui Yang,
  • Shunquan Lin and
  • Yongshun Gao

30 December 2019

The age pathway is important for regulating flower bud initiation in flowering plants. The major regulators in this pathway are miR156 and SPL transcription factors. To date, SPL genes have been identified in many species of plants. Loquat, as a wood...

  • Article
  • Open Access
3 Citations
2,884 Views
15 Pages

2 September 2022

SQUAMOSA Promoter-Binding Protein-Like (SPL) genes encode plant-specific transcription factors which bind to the SQUAMOSA promoter of the MADS-box genes to regulate its expression. It plays important regulatory roles in floral induction and developme...

  • Article
  • Open Access
1 Citations
1,222 Views
19 Pages

8 February 2025

Plant-specific transcription factors known as SQUAMOSA promoter binding protein-like (SPL) genes are essential for development, growth, and abiotic stress responses. While the SPL gene family has been extensively studied in various plant species, a s...

  • Article
  • Open Access
7 Citations
2,427 Views
15 Pages

Transcription Factor SmSPL2 Inhibits the Accumulation of Salvianolic Acid B and Influences Root Architecture

  • Xiangzeng Wang,
  • Yao Cao,
  • Jiaxin Yang,
  • Tong Zhang,
  • Qianqian Yang,
  • Yanhua Zhang,
  • Donghao Wang and
  • Xiaoyan Cao

4 November 2022

The SQUAMOSA PROMOTER-BINDING PROTEIN-LIKE (SPL) transcription factor play vital roles in plant growth and development. Although 15 SPL family genes have been recognized in the model medical plant Salvia miltiorrhiza Bunge, most of them have not been...

  • Article
  • Open Access
12 Citations
2,913 Views
11 Pages

4 March 2024

MicroRNAs (miRNAs) are a class of endogenous, non-coding small-molecule RNAs that usually regulate the expression of target genes at the post-transcriptional level. miR156 is one of a class of evolutionarily highly conserved miRNA families. SQUAMOSA...

  • Review
  • Open Access
3 Citations
2,050 Views
17 Pages

In plants, SPL is a distinct family of transcription factors. Its protein structure possesses a highly conserved SBP domain comprising two zinc finger structures and nuclear localization regions, and microRNAs (miR156) control the transcriptional exp...

  • Article
  • Open Access
641 Views
21 Pages

20 November 2025

Vegetative to reproductive phase transition is an important developmental process in flowering plants, regulated in part by microRNAs that repress target genes post-transcriptionally. However, the role of miR156 and its target Squamosa Promoter Bindi...

  • Article
  • Open Access
24 Citations
5,087 Views
14 Pages

Time to flower, a process either referring to juvenile–adult phase change or vegetative–reproductive transition, is strictly controlled by an intricate regulatory network involving at least both FT/TFL1 and the micro RNA (miR)156-regulate...

  • Article
  • Open Access
14 Citations
3,349 Views
18 Pages

10 February 2022

Plant leaf patterns and shapes are spectacularly diverse. Changing the complexity of leaflet numbers is a valuable approach to increase its nutrition and photosynthesis. Alfalfa (Medicago sativa) is the most important forage legume species and has di...

  • Article
  • Open Access
29 Citations
3,518 Views
15 Pages

SmSPL6 Induces Phenolic Acid Biosynthesis and Affects Root Development in Salvia miltiorrhiza

  • Yao Cao,
  • Rui Chen,
  • Wen-Tao Wang,
  • Dong-Hao Wang and
  • Xiao-Yan Cao

Salvia miltiorrhiza is a renowned model medicinal plant species for which 15 SQUAMOSA PROMOTER BINDING PROTEIN-LIKE (SPL) family genes have been identified; however, the specific functions of SmSPLs have not been well characterized as of yet. For thi...

  • Article
  • Open Access
20 Citations
4,432 Views
15 Pages

BZR1 Physically Interacts with SPL9 to Regulate the Vegetative Phase Change and Cell Elongation in Arabidopsis

  • Lingyan Wang,
  • Ping Yu,
  • Jinyang Lyu,
  • Yanfei Hu,
  • Chao Han,
  • Ming-Yi Bai and
  • Min Fan

27 September 2021

As sessile organisms, the precise development phase transitions are very important for the success of plant adaptability, survival and reproduction. The transition from juvenile to the adult phase—referred to as the vegetative phase change—is signifi...

  • Article
  • Open Access
12 Citations
4,081 Views
13 Pages

11 September 2019

SQUAMOSA-promoter binding protein-like (SPL) proteins are plant-specific transcript factors that play essential roles in plant growth and development. Although many SPL genes have been well characterized in model plants like Arabidopsis, rice and tom...

  • Article
  • Open Access
10 Citations
2,083 Views
20 Pages

9 April 2024

SPL (SQUAMOSA promoter binding protein-like), as one family of plant transcription factors, plays an important function in plant growth and development and in response to environmental stresses. Despite SPL gene families having been identified in var...

  • Article
  • Open Access
60 Citations
16,706 Views
17 Pages

2 January 2009

The SQUAMOSA PROMOTER BINDING PROTEIN–LIKE (SPL) gene family is an SBP-box transcription family in Arabidopsis. While several physiological responses to SPL genes have been reported, their biological role remains elusive. Here, we use a combined anal...

  • Article
  • Open Access
7 Citations
2,247 Views
20 Pages

Genome-Wide Identification of Litchi SPL Gene Family and Expression Analysis in Pericarp Anthocyanin Biosynthesis

  • Ziqiang Xu,
  • Jiayun Wu,
  • Xiangyang Jing,
  • Faiza Shafique Khan,
  • Yanzhao Chen,
  • Zhe Chen,
  • Hongna Zhang and
  • Yongzan Wei

During the ripening of litchi (Litchi chinensis Sonn.) fruit, anthocyanin biosynthesis is crucial in providing vibrant coloring. Previous studies on anthocyanin-related transcription factors have made significant discoveries relating to plants. Howev...

  • Article
  • Open Access
9 Citations
3,010 Views
14 Pages

20 January 2022

SQUAMOSA PROMOTER BINDING PROTEIN-LIKE (SPL) genes, as unique plant transcription factors, play important roles in plant developmental regulation and stress response adaptation. Although mulberry is a commercially valuable tree species, there have be...

  • Article
  • Open Access
9 Citations
4,020 Views
15 Pages

Copper (Cu) is one of the most indispensable micronutrients, and proper Cu homeostasis is required for plants to maintain essential cellular functions. Plants activate the Cu uptake system during Cu limitation. Although SPL7 (SQUAMOSA PROMOTER BINDIN...

  • Article
  • Open Access
2 Citations
1,874 Views
39 Pages

Aluminum Stress Response Is Regulated Through a miR156/SPL13 Module in Medicago sativa

  • Gamalat Allam,
  • Solihu K. Sakariyahu,
  • Binghui Shan,
  • Banyar Aung,
  • Tim McDowell,
  • Yousef Papadopoulos,
  • Mark A. Bernards and
  • Abdelali Hannoufa

27 June 2025

Background: Aluminum (Al) toxicity severely limits Medicago sativa (alfalfa) production on acidic soils, resulting in major yield losses worldwide. The highly conserved miRNA156 (miR156) functions by downregulating at least 11 SQUAMOSA promoter-bindi...

  • Article
  • Open Access
3 Citations
2,009 Views
15 Pages

Comprehensive Analyses of Four PhNF-YC Genes from Petunia hybrida and Impacts on Flowering Time

  • Jing Bin,
  • Qinghua Tan,
  • Shiyun Wen,
  • Licheng Huang,
  • Huimin Wang,
  • Muhammad Imtiaz,
  • Zhisheng Zhang,
  • Herong Guo,
  • Li Xie and
  • Qian Wei
  • + 1 author

6 March 2024

Nuclear Factor Y (NF-Y) is a class of heterotrimeric transcription factors composed of three subunits: NF-A, NF-YB, and NF-YC. NF-YC family members play crucial roles in various developmental processes, particularly in the regulation of flowering tim...

  • Article
  • Open Access
1 Citations
903 Views
18 Pages

Evolutionary Insights and Flowering Regulation of SPLs in Coconut Palm

  • Runan Chen,
  • Yalan Feng,
  • Jin Zhou,
  • Ying Wang,
  • Fengyi Zhang,
  • Shazia Rehman,
  • Zhuang Yang,
  • Zifen Lao,
  • Hang Xu and
  • Wei Xia
  • + 2 authors

14 August 2025

Squamosa Promoter-Binding Protein Like (SPL) is a critical transcription factor that plays a significant role in regulating plant growth and development. Mining the coconut SPL family offers valuable insights into the regulation of important agronomi...

  • Article
  • Open Access
7 Citations
2,617 Views
15 Pages

Early anther morphogenesis is a crucial process for male fertility in plants, governed by the transcription factor SPL. While the involvement of AGAMOUS (AG) in SPL activation and microsporogenesis initiation is well established, our understanding of...

  • Article
  • Open Access
7 Citations
2,736 Views
15 Pages

4 September 2023

The SPL (SQUAMOSA-promoter binding protein-like) gene family is one of the largest plant transcription factors and is known to be involved in the regulation of plant growth, development, and stress responses. The genome-wide analysis of SPL gene memb...

  • Article
  • Open Access
12 Citations
3,276 Views
22 Pages

Genome-Wide Identification and Characterization of SPL Family Genes in Chenopodium quinoa

  • Hongmei Zhao,
  • Huaqi Cao,
  • Mian Zhang,
  • Sufang Deng,
  • Tingting Li and
  • Shuping Xing

16 August 2022

SQUAMOSA PROMOTER BINDING PROTEIN-LIKE (SPL) genes encode a large family of plant-specific transcription factors that play important roles in plant growth, development, and stress responses. However, there is little information available on SPL genes...

  • Article
  • Open Access
4 Citations
2,349 Views
16 Pages

31 August 2023

Transcription factors SQUAMOSA Promoter-binding Protein-like (SPL) play a crucial role in regulating plant response to stress, root development, and flower production. However, analysis of SPL gene families in the three rubber-producing plants Taraxa...

  • Article
  • Open Access
3 Citations
2,392 Views
16 Pages

SPL transcription factors affect plant growth and development, including blooming and photoperiod control. The investigation began with transcriptome data screening of 28 JrSPL genes in walnut (Junglans regia L.) ‘Wen185’. These genes wer...

  • Article
  • Open Access
3 Citations
1,320 Views
24 Pages

PavSPL Expression Dynamics in Fruits and Seeds and in Relation to Endocarp Lignification Status During the Transition from Development to Ripening in Sweet Cherry

  • Matías Zavala,
  • Marcela Menares,
  • Orlando Acevedo,
  • Mirna Melo,
  • Carlos Nuñez,
  • Camila Arancibia,
  • Romina Pedreschi,
  • José Manuel Donoso,
  • Lee A. Meisel and
  • Nathalie Kuhn
  • + 1 author

The transition to ripening in non-climacteric species is governed by several signals, including hormones that enhance or counteract the abscisic acid (ABA)-promoting effect. The SQUAMOSA Promoter-binding protein-Like (SPL) transcription factors are i...

  • Article
  • Open Access
2 Citations
3,083 Views
15 Pages

5 December 2022

Phytochrome-interacting factors (PIFs) are transcription factors with the basic helix–loop–helix (bHLH) domain. As integration factors between different signal pathways, members of the PIF protein family regulate many aspects of plant gro...

  • Article
  • Open Access
3 Citations
1,810 Views
11 Pages

Natural Variation in the Promoter of GmSPL9d Affects Branch Number in Soybean

  • Duo Zhao,
  • Haowei Zheng,
  • Jiajia Li,
  • Mingyue Wan,
  • Kuo Shu,
  • Wenhui Wang,
  • Xiaoyu Hu,
  • Yu Hu,
  • Lijuan Qiu and
  • Xiaobo Wang

The branch number is a crucial factor that influences density tolerance and is closely associated with the yield of soybean. However, its molecular regulation mechanisms remain poorly understood. This study cloned a candidate gene GmSPL9d for regulat...

  • Article
  • Open Access
22 Citations
4,089 Views
25 Pages

OsSPLs Regulate Male Fertility in Response to Different Temperatures by Flavonoid Biosynthesis and Tapetum PCD in PTGMS Rice

  • Yujun Sun,
  • Ming Fu,
  • Lei Wang,
  • Yunxiu Bai,
  • Xueliang Fang,
  • Qian Wang,
  • Ying He and
  • Hanlai Zeng

Photoperiod and thermo-sensitive genic male sterile (PTGMS) rice is an important resource for two line hybrid rice production. The SQUAMOSA–promoter binding, such as the (SPL) gene family, encode the plant specific transcription factors that re...

  • Article
  • Open Access
12 Citations
3,160 Views
24 Pages

14 November 2022

The transition from vegetative to reproductive growth is important for controlling the flowering of Lycoris radiata. However, the genetic control of this complex developmental process remains unclear. In this study, 18 shoot apical meristem (SAM) sam...

  • Article
  • Open Access
14 Citations
3,321 Views
16 Pages

9 October 2021

SQUAMOSA PROMOTER BINDING PROTEIN-LIKE (SPL) transcription factors play critical roles in regulating diverse aspects of plant growth and development, including vegetative phase change, plant architecture, anthocyanin accumulation, lateral root growth...

  • Article
  • Open Access
2 Citations
1,248 Views
18 Pages

Genome-Wide Identification of Ginkgo biloba SPL Gene Family and Expression Analysis in Flavonoid Biosynthesis and Water Stress

  • Meiling Ming,
  • Mulin Yi,
  • Chunyue Qin,
  • Luyao Yan,
  • Yuhan Sun,
  • Juan Zhang,
  • Fuliang Cao and
  • Fangfang Fu

SQUAMOSA promoter-binding protein-like (SPL) transcription factors specific to plants are vital for regulating growth, development, secondary metabolite biosynthesis, and responses to both biotic and abiotic stresses. Despite their importance, no sys...

  • Article
  • Open Access
11 Citations
3,356 Views
18 Pages

Genome-Wide Identification and Expression Analysis of the SPL Gene Family in Three Orchids

  • Xuewei Zhao,
  • Mengmeng Zhang,
  • Xin He,
  • Qinyao Zheng,
  • Ye Huang,
  • Yuanyuan Li,
  • Sagheer Ahmad,
  • Dingkun Liu,
  • Siren Lan and
  • Zhongjian Liu

SPL transcription factors regulate important processes such as plant growth and development, metabolic regulation, and abiotic stress. They play crucial roles in the development of flower organs. However, little is known about the characteristics and...

  • Article
  • Open Access
1,242 Views
15 Pages

Genome-Wide Identification and Expression Analysis of the SPL Gene Family in Solanum melongena (Eggplant)

  • Hefen Cheng,
  • Zhiliang Li,
  • Baojuan Sun,
  • Wei Zhao,
  • Songyuan Zhang,
  • Tao Li,
  • Qian You and
  • Dinggang Zhou

14 February 2025

The SPL (SQUAMOSA promoter-binding protein-like) transcription factor gene family plays a crucial role in the growth of plants, including fruit development. Although the SPL gene family has been widely studied in many plants, it remains unexplored in...

  • Article
  • Open Access
1 Citations
1,413 Views
15 Pages

ZmSPL12 Enhances Root Penetration and Elongation in Maize Under Compacted Soil Conditions by Responding to Ethylene Signaling

  • Hua Xu,
  • Zhigang Zheng,
  • Lei Ma,
  • Qingyun Zhang,
  • Lian Jin,
  • Ke Zhang,
  • Junjie Zou,
  • Hada Wuriyanghan and
  • Miaoyun Xu

17 December 2024

Soil compaction poses a significant challenge in modern agriculture, as it constrains root development and hinders crop growth. The increasing evidence indicated that various phytohormones collaborate in distinct root zones to regulate root growth in...

  • Article
  • Open Access
3 Citations
1,459 Views
14 Pages

20 November 2024

Garden dahlias (Dahlia pinnata) are popular for their wide range of color variations, with polychromatic cultivars enhancing their ornamental value. Previous studies on the anthocyanin biosynthetic pathway (ABP) have indicated that the post-transcrip...

  • Article
  • Open Access
90 Citations
7,776 Views
14 Pages

9 October 2018

Ultra-high performance liquid chromatography coupled with photo-diode array detector and electrospray ionization-mass spectrometry was employed to analyze the major fatty acids in Spirulina platensis 95% ethanol extract (SPL95). The effects of SPL95...

  • Article
  • Open Access
27 Citations
3,634 Views
20 Pages

2 September 2021

As an essential nutrient, copper (Cu) scarcity causes a decrease in agricultural production. Cu deficiency responses include the induction of several microRNAs, known as Cu-miRNAs, which are responsible for degrading mRNAs from abundant and dispensab...

  • Article
  • Open Access
19 Citations
5,849 Views
19 Pages

Downregulation of S1P Lyase Improves Barrier Function in Human Cerebral Microvascular Endothelial Cells Following an Inflammatory Challenge

  • Bisera Stepanovska,
  • Antonia I. Lange,
  • Stephanie Schwalm,
  • Josef Pfeilschifter,
  • Sina M. Coldewey and
  • Andrea Huwiler

13 February 2020

Sphingosine 1-phosphate (S1P) is a key bioactive lipid that regulates a myriad of physiological and pathophysiological processes, including endothelial barrier function, vascular tone, vascular inflammation, and angiogenesis. Various S1P receptor sub...

  • Feature Paper
  • Article
  • Open Access
8 Citations
3,265 Views
17 Pages

18 May 2022

Trifolium repens is the most widely cultivated perennial legume forage in temperate region around the world. It has rich nutritional value and good palatability, seasonal complementarity with grasses, and can improve the feed intake and digestibility...

  • Article
  • Open Access
7 Citations
2,845 Views
15 Pages

Loss of S1P Lyase Expression in Human Podocytes Causes a Reduction in Nephrin Expression That Involves PKCδ Activation

  • Faik Imeri,
  • Bisera Stepanovska Tanturovska,
  • Roxana Manaila,
  • Hermann Pavenstädt,
  • Josef Pfeilschifter and
  • Andrea Huwiler

7 February 2023

Sphingosine 1-phosphate (S1P) lyase (SPL, Sgpl1) is an ER-associated enzyme that irreversibly degrades the bioactive lipid, S1P, and thereby regulates multiple cellular functions attributed to S1P. Biallelic mutations in the human Sglp1 gene lead to...

  • Article
  • Open Access
51 Citations
5,093 Views
17 Pages

Roles of the GA-mediated SPL Gene Family and miR156 in the Floral Development of Chinese Chestnut (Castanea mollissima)

  • Guosong Chen,
  • Jingtong Li,
  • Yang Liu,
  • Qing Zhang,
  • Yuerong Gao,
  • Kefeng Fang,
  • Qingqin Cao,
  • Ling Qin and
  • Yu Xing

Chestnut (Castanea mollissima) is a deciduous tree species with major economic and ecological value that is widely used in the study of floral development in woody plants due its monoecious and out-of-proportion characteristics. Squamosa promoter-bin...

  • Article
  • Open Access
3 Citations
2,079 Views
18 Pages

Expression and Functional Identification of SPL6/7/9 Genes under Drought Stress in Sugarbeet Seedlings

  • Hui Wang,
  • Shengyi Zhu,
  • Chao Yang,
  • Deyong Zeng,
  • Chengfei Luo,
  • Cuihong Dai,
  • Dayou Cheng and
  • Xiaohong Lv

18 August 2024

Sugar beet is a significant sugar crop in China, primarily cultivated in arid regions of the north. However, drought often affects sugar beet cultivation, leading to reduced yield and quality. Therefore, understanding the impact of drought on sugar b...

  • Article
  • Open Access
368 Views
15 Pages

GhmiR156-GhSPL2 Module Regulates Anthocyanin Biosynthesis of Ray Florets in Gerbera hybrida

  • Mengdi Li,
  • Bingbing Liao,
  • Shuyuan Shi,
  • Qishan Luo,
  • Yanbo Chen,
  • Xiaojing Wang and
  • Yaqin Wang

27 December 2025

Anthocyanins, biosynthesized through the flavonoid pathway, critically determine floral coloration and ornamental value in plants. While floral development has been extensively studied in Gerbera hybrida, the microRNA-mediated regulation of anthocyan...

  • Article
  • Open Access
5 Citations
1,497 Views
16 Pages

Stem strength plays a crucial role in the growth and development of plants, as well as in their flowering and fruiting. It not only impacts the lodging resistance of crops, but also influences the ornamental value of ornamental plants. Stem developme...

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