Search Results (9)

This paper presents a method to design a suspension controller with a human body model for ride comfort improvement and motion sickness mitigation. Generally, it has been known that the vertical acceleration of a sprung mass should be reduced for ride comfort. On the other hand, recent studies have shown that, combined, the vertical acceleration and pitch rate of a sprung mass are key factors that cause motion sickness. However, those variables have been considered with respect to the center of gravity of a sprung mass. For motion sickness mitigation, the vertical acceleration of a human head should be also considered. In this paper, the vertical accelerations and pitch rates of a sprung mass and a human head are controlled by a suspension controller for ride comfort improvement and motion sickness mitigation. For the controller design, a half-car and human body models are adopted. With those models, several types of static output feedback suspension controller are designed with linear quadratic optimal control methodology. To reduce the pitch rate of the sprung mass and the vertical acceleration of the head, a filtered-X LMS algorithm is adopted as an adaptive feedforward algorithm and combined with the static output feedback controllers. A frequency response analysis and simulation are performed with the designed controllers on vehicle simulation software, CarSim^®. From the simulation results, it is shown that the proposed controllers can effectively reduce the vertical accelerations and the pitch rate of the sprung mass and the human head. Full article

This paper presents a design method of a suspension controller with an adaptive feedforward algorithm for ride comfort enhancement and motion sickness mitigation. Recently, it was shown that motion sickness is caused by combined heave and pitch motions of a sprung mass within the range of 0.8 and 8 Hz. For this reason, it is necessary to design a suspension controller for the purpose of reducing the heave and pitch vibration of a sprung mass within this range. To represent the heave acceleration and the pitch rate of a sprung mass, a 4-DOF half-car model is adopted as a vehicle model. For easy implementation in a real vehicle, a static output feedback control is adopted instead of a full-state one. To reduce the heave acceleration of a sprung mass for ride comfort enhancement, a linear quadratic SOF controller is designed. To reduce the pitch rate of a sprung mass for motion sickness mitigation, a filtered-X LMS algorithm is applied. To validate the method, simulation on vehicle simulation software is conducted. From the simulation results, it is shown that the proposed method is effective for ride comfort enhancement and motion sickness mitigation. Full article

The parasites Trypanosoma brucei (Tb) and Leishmania major (Lm) cause the tropical diseases sleeping sickness, nagana, and cutaneous leishmaniasis. Every year, millions of humans, as well as animals, living in tropical to subtropical climates fall victim to these illnesses’ health threats. The parasites’ frequent drug resistance and widely spread natural reservoirs heavily impede disease prevention and treatment. Due to pteridine auxotrophy, trypanosomatid parasites have developed a peculiar enzyme system consisting of dihydrofolate reductase-thymidylate synthase (DHFR-TS) and pteridine reductase 1 (PTR1) to support cell survival. Extending our previous studies, we conducted a comparative study of the T. brucei (TbDHFR, TbPTR1) and L. major (LmDHFR, LmPTR1) enzymes to identify lead structures with a dual inhibitory effect. A pharmacophore-based in silico screening of three natural product databases (approximately 4880 compounds) was performed to preselect possible inhibitors. Building on the in silico results, the inhibitory potential of promising compounds was verified in vitro against the recombinant DHFR and PTR1 of both parasites using spectrophotometric enzyme assays. Twelve compounds were identified as dual inhibitors against the Tb enzymes (0.2 μM < IC₅₀ < 85.1 μM) and ten against the respective Lm enzymes (0.6 μM < IC₅₀ < 84.5 μM). These highly promising results may represent the starting point for the future development of new leads and drugs utilizing the trypanosomatid pteridine metabolism as a target. Full article

Currently, there are no free databases of 3D point clouds and images for seedling phenotyping. Therefore, this paper describes a platform for seedling scanning using 3D Lidar with which a database was acquired for use in plant phenotyping research. In total, 362 maize seedlings were recorded using an RGB camera and a SICK LMS4121R-13000 laser scanner with angular resolutions of 45° and 0.5° respectively. The scanned plants are diverse, with seedling captures ranging from less than 10 cm to 40 cm, and ranging from 7 to 24 days after planting in different light conditions in an indoor setting. The point clouds were processed to remove noise and imperfections with a mean absolute precision error of 0.03 cm, synchronized with the images, and time-stamped. The database includes the raw and processed data and manually assigned stem and leaf labels. As an example of a database application, a Random Forest classifier was employed to identify seedling parts based on morphological descriptors, with an accuracy of 89.41%. Full article

The aim of this study was to test the flow from long working hours to sickness presenteeism behavior and its outcomes for employees, while integrating intrinsic and extrinsic work value orientations as moderators in the process. We employed a two-wave design with a five-month interval. Data were obtained from 275 employees in Taiwan. The results of latent moderated structural equations (LMS) revealed that long working hours were positively associated with presenteeism, which in turn was negatively related to employees’ well-being and job performance. Furthermore, the negative indirect effect of working long hours on job performance via presenteeism was weaker for those with a higher intrinsic work value orientation. The negative indirect effect of working long hours on well-being via presenteeism was weaker for those with a higher extrinsic work value orientation. We demonstrated that the long-term impact of presenteeism behavior could be understood by viewing work value orientations as resource gains to compensate resource depletion in a demanding work context. This resource dynamism is pivotal to realizing the functional or dysfunctional outcomes of presenteeism behavior. Theoretical and managerial implications of the findings for employees’ well-being and organizational effectiveness are discussed. Full article

The COVID-19 pandemic led to the closure of universities and colleges throughout the world, with the hope that public health officials’ suggestion of social distancing would help flatten the sickness curve and reduce overall mortality from the outbreak. However, the Learning Management System (LMS) is the perfect approach for fostering the dedication of students to content in education like sustainability. Previous studies have seldom investigated an integrated approach in the context of LMS in industrialized nations. In addition, this paper aims to include a literature analysis of recent research conducted during the COVID-19 pandemic in the area of LMS usage, as well as to investigate variables predicting the usage of LMS by higher education students during the COVID-19 pandemic for students’ engagement. On the basis of LMS usage data obtained from an online survey, structural equation modeling (SEM) and route analysis were utilized to verify the research model, a survey consisting of student LMS users King Saud University. The findings showed that the desire of students to use LMS had beneficial effects during the COVID-19 pandemic on learning as sustainability engagement. Also, student-perceived closeness, peer references and subjective well-being are favorably associated with the perceived ease of use and perceived usefulness, this, in turn, influences students’ intentions to utilize, which, in turn, effects the usage of LMS for student engagement during COVID-19. Full article

This paper introduces GRover (the grapevine rover), an adaptable mobile platform for the deployment and testing of proximal imaging sensors in vineyards for the non-destructive assessment of trunk and cordon volume and pruning weight. A SICK LMS-400 light detection and ranging (LiDAR) radar mounted on GRover was capable of producing precise (±3 mm) 3D point clouds of vine rows. Vineyard scans of the grapevine variety Shiraz grown under different management systems at two separate locations have demonstrated that GRover is able to successfully reproduce a variety of vine structures. Correlations of pruning weight and vine wood (trunk and cordon) volume with LiDAR scans have resulted in high coefficients of determination (R² = 0.91 for pruning weight; 0.76 for wood volume). This is the first time that a LiDAR of this type has been extensively tested in vineyards. Its high scanning rate, eye safe laser and ability to distinguish tissue types make it an appealing option for further development to offer breeders, and potentially growers, quantified measurements of traits that otherwise would be difficult to determine. Full article

We propose an expectation maximization (EM) strategy for improving the precision of time of flight (ToF) light detection and ranging (LiDAR) scanners. The novel algorithm statistically accounts not only for the bias induced by temperature changes in the laser diode, but also for the multi-modality of the measurement noises that is induced by mode-hopping effects. Instrumental to the proposed EM algorithm, we also describe a general thermal dynamics model that can be learned either from just input-output data or from a combination of simple temperature experiments and information from the laser’s datasheet. We test the strategy on a SICK LMS 200 device and improve its average absolute error by a factor of three. Full article

The geometric characterisation of tree orchards is a high-precision activity comprising the accurate measurement and knowledge of the geometry and structure of the trees. Different types of sensors can be used to perform this characterisation. In this work a terrestrial LIDAR sensor (SICK LMS200) whose emission source was a 905-nm pulsed laser diode was used. Given the known dimensions of the laser beam cross-section (with diameters ranging from 12 mm at the point of emission to 47.2 mm at a distance of 8 m), and the known dimensions of the elements that make up the crops under study (flowers, leaves, fruits, branches, trunks), it was anticipated that, for much of the time, the laser beam would only partially hit a foreground target/object, with the consequent problem of mixed pixels or edge effects. Understanding what happens in such situations was the principal objective of this work. With this in mind, a series of tests were set up to determine the geometry of the emitted beam and to determine the response of the sensor to different beam blockage scenarios. The main conclusions that were drawn from the results obtained were: (i) in a partial beam blockage scenario, the distance value given by the sensor depends more on the blocked radiant power than on the blocked surface area; (ii) there is an area that influences the measurements obtained that is dependent on the percentage of blockage and which ranges from 1.5 to 2.5 m with respect to the foreground target/object. If the laser beam impacts on a second target/object located within this range, this will affect the measurement given by the sensor. To interpret the information obtained from the point clouds provided by the LIDAR sensors, such as the volume occupied and the enclosing area, it is necessary to know the resolution and the process for obtaining this mesh of points and also to be aware of the problem associated with mixed pixels. Full article