Search Results (9,448)

Hybrid terahertz (THz)/free-space optical (FSO) systems offer a promising paradigm for high-capacity, all-weather wireless communication, yet their deployment is often hindered by the bulky size and high complexity of discrete transceivers. This paper experimentally demonstrates a low-complexity hybrid THz/FSO transmission architecture featuring a unified photonic transmitter. By leveraging a polymethyl methacrylate (PMMA) plate serving as a dichroic beam combiner—which reflects the 1550 nm optical signal while transmitting the 300 GHz THz signal—we realize simultaneous signal propagation over a shared aperture and link. Photonics-aided techniques are employed to generate both carriers, ensuring system integration and coherence. The experimental results verify that both the THz and FSO links independently support 30-GBaud quadrature phase-shift keying (QPSK) transmission over a 10-m wireless distance, achieving a net data rate of 60 Gbps per link while satisfying the 7% hard-decision forward error correction (HD-FEC) threshold of 3.8 × 10⁻³. This work validates the feasibility of shared-transmitter designs and provides a compact, cost-effective solution for future high-speed fronthaul/backhaul networks. Full article

Membrane separation technology is extensively used in water treatment. However, during long-term operation, biofouling caused by bacteria and other microorganisms significantly limits the service life of membranes. Introducing antibacterial nanomaterials onto the membrane surface or into the internal structure is an effective way to combat biofouling. This review systematically summarizes recent progress in antibacterial membranes modified with different nanomaterials. First, we classify antibacterial nanomaterials by dimensionality and highlight their physicochemical properties and effects on overall membrane performance. Furthermore, we summarize the advantages, disadvantages, and applicability of three antibacterial nanomaterial modification strategies for membranes, including surface coating, grafting, and blending. Subsequently, we analyze in depth the main antibacterial mechanisms that enhance membrane performance, including metal ion release, reactive oxygen species oxidation, physical contact disruption, and anti-adhesion, as well as their synergistic effects. Finally, we critically evaluate the remaining challenges, such as interfacial compatibility between nanomaterials and polymers, controlled release of metal ions, and environmental safety. This review provides a reference for the rational design of high-performance antibacterial membranes. Full article

Electric dynamometer test benches generate heterogeneous multi-channel logs whose structural completeness, physical consistency, and operating-condition support vary across files. We propose Coupling-Gated Data Quality Index (CG-DQI) sample weighting, a fold-local preparation protocol for 60 s next-window temperature-change prediction. Deployable weights use training-side structural and physical quality signals, while a target-magnitude coupling gate screens candidate association with the absolute target. The dataset contains 30,093 valid windows from 134 files and 30 date-defined campaigns. File-level leave-one-file-out validation reduced Ridge MAE from 0.7035 to 0.6932 °C and the mean MAE across three fixed Random Forest initializations from 0.4556 to 0.4489 °C per window. Strict nested leave-one-campaign-out analysis retained sparse CG-DQI in all 30 folds and yielded a campaign-level Ridge MAE difference of 0.0152 °C with a 95% bootstrap confidence interval (CI) of 0.0054–0.0309, while the 99th percentile absolute error (P99) increased by 0.0710 °C. Fixed-parameter XGBoost preserved a positive mean MAE direction, although its campaign interval crossed zero. CG-DQI, therefore, provides a traceable MAE-oriented preparation option within the present bench and campaign range; tail-sensitive and cross-device use requires an explicit constraint or recalibration. Full article

Corrosion of steel reinforcement is a major cause of deterioration in reinforced concrete (RC) structures exposed to aggressive environments. Although fiber-reinforced polymer (FRP) reinforcement provides excellent corrosion resistance, its confinement effectiveness in RC columns has not been fully understood. This study experimentally investigated the axial compressive behavior of rectangular RC short columns reinforced with steel, carbon fiber-reinforced polymer (CFRP), and glass fiber-reinforced polymer (GFRP) bars. Ten specimens with different reinforcement types and stirrup configurations were tested under monotonic axial compression to evaluate compressive strength, axial strain response, deformation behavior, failure mechanisms, and confinement performance. The results indicated that the contribution of FRP reinforcement depended on the reinforcement configuration and confinement mechanism. Specimens reinforced with CFRP longitudinal bars exhibited higher axial capacity than the steel-reinforced control specimen within the tested configurations; however, the influence of the longitudinal reinforcement ratio should also be considered. GFRP stirrups exhibited confinement behavior comparable to CFRP stirrups, whereas CFRP stirrups experienced premature fracture at bent corner regions, which reduced their confinement effectiveness and deformation capacity. Reducing stirrup spacing from 150 mm to 75 mm provided limited improvement in compressive strength because of premature stirrup failure and insufficient development of confinement effects. Existing confinement models tended to overestimate the post-peak response of FRP-reinforced columns. These preliminary findings provide experimental insights into the confinement behavior of FRP-reinforced concrete columns and contribute to the development of improved analytical models. Full article

Accurate remaining useful life (RUL) prediction of lithium-ion batteries is critical for reliable operation of the system. The performance evolution of lithium-ion batteries shows long-range dependence and capacity regeneration. However, existing performance evolution models fail to properly consider the joint effect of long-range dependence and capacity regeneration, and consequently have a deficiency in mechanism interpretability, which may limit the prediction accuracy of RUL. To address this gap, this paper separately characterizes the degradation and regeneration processes of the discharge capacity, and proposes a novel discharge capacity evolution model incorporating fractional Brownian motion and the Poisson capacity regeneration process. For the estimation problem of the model parameters caused by the Poisson regeneration, we approximately transform the proposed model to one with independent increments according to the weak convergence theorem, and then develop a maximum likelihood estimation method. From a limit perspective and using the theory of total probability, we derive the distribution of RUL, and provide the point estimation of RUL. Finally, we utilize the data set of lithium-ion batteries produced by NASA to verify the effectiveness of the proposed method, and the mean absolute errors of the proposed method are declined by at least 24% compared to the existing methods. Full article

Recent advances in robotics have highlighted the importance of multimodal perception for dexterous manipulation in contact-rich environments. Here we present BiTAT, a bimanual tactile-augmented teleoperation system for collecting multimodal human demonstrations and learning manipulation policies. The system integrates custom capacitive tactile sensors into parallel grippers and displays the resulting contact-deformation images to the operator. We evaluated the system in four controlled laboratory tasks: USB removal/insertion, bottle cap unscrewing, cucumber peeling, and toothpaste squeezing. In a pilot repeated-measures study with eight laboratory participants, visual tactile feedback was associated with success-rate increases of 12.5–32.5 percentage points and shorter completion times among successful trials. We further propose a multimodal Diffusion Policy that fuses visual, tactile, and proprioceptive features through a Transformer encoder. In two fixed-layout autonomous tasks, the complete model achieved higher observed success rates than the vision-only baseline, including a 45-percentage-point difference in the 50-demonstration toothpaste-squeezing setting. Together, these results demonstrate the feasibility of the proposed hardware–policy pipeline and suggest that tactile augmentation benefits both human teleoperation and learned manipulation policies in contact-rich tasks. Full article

Traditional villages in ecologically sensitive areas face structural dilemmas between preservation-induced stagnation and excessive commercialization under the combined pressures of rural revitalization and ecological protection. This study investigates the spatial differentiation and revitalization strategies of 250 nationally recognized traditional villages in the Xin’an River Basin from a resilience-inspired spatial planning perspective. GIS-based kernel density estimation and the Nearest Neighbor Index were applied to characterize spatial distribution patterns, while GeoDetector was used to evaluate the explanatory power of key natural and anthropogenic factors. The Minimum Cumulative Resistance (MCR) model was used to construct revitalization-suitability zones; resilience capacities were not directly measured; instead, they were used as heuristic planning concepts for interpreting the three consolidated priority regions: Core Conservation (absorptive), Moderate Revitalization (adaptive), and Ecological Conservation (transformative/reserve). The results reveal a pattern of small-scale clustering and large-scale dispersion. A total of 69.2% of the villages were located within 1.5 km of rivers, and 95.2% were situated below 500 m in elevation. Distance to rivers (q = 0.2345) and distance to roads (q = 0.1441) showed the highest explanatory power among the eight candidate factors. The framework provides resilience-inspired spatial guidance for balancing heritage conservation, ecological protection, and rural revitalization. Full article

Benefiting from excellent high-frequency characteristics and superior radiation tolerance, InP is an indispensable material for next-generation high-speed communications, widely applied in optical communication, 6G radio frequency chips, AI optical interconnection, and aerospace radiation-hardened electronics. Although ion implantation greatly promotes the performance optimization of InP-based devices, it inevitably induces lattice displacement defects that degrade device reliability. Hence, quantitative evaluation of the threshold displacement energy (TDE) and dominant defect configurations in InP is essential. Our calculations reveal that the average threshold displacement energy is 18.20 eV for In atoms and 18.94 eV for P atoms. The E_d distributions for both In and P atoms predominantly lie below 30 eV and rarely exceed 40 eV. From 150 K to 900 K, In and P have a large mass difference and exhibit distinct temperature-dependent trends. The threshold displacement energy of In decreases with increasing temperature, whereas that of P rises as temperature increases. Based on the structural analysis of Frenkel pairs formed by displaced atoms, the dominant interstitial configurations are identified. These results provide detailed insights for damage evaluation and defect structure characterization in InP, benefiting ion implantation process optimization and radiation-hardening design of InP electronic devices. Full article

Physics-informed neural networks (PINNs) approximate partial differential equations (PDEs) by enforcing governing equations and boundary conditions during training, but their accuracy depends on how collocation points are distributed and updated. We propose spatiotemporal compositional active sampling (STCAS), a reference-assisted offline configuration procedure that uses an analytic or high-accuracy numerical solution to rank complete three-stage sampling plans. It screens eight fixed rules, forms a task-specific shortlist, and evaluates bounded fixed, switched, and locally blended plans with independent selection sets and a composition guard. A safety-anchor decision retains the standard PINN unless the selected candidate is at least 5% better. Across five evaluations on 18 analytically specified two-dimensional Poisson tasks, this protocol improves 16 task means and ties two, reducing aggregate relative-$L_2$ error by 12.8% (hierarchical-bootstrap 95% interval $[6.78\%,19.32\%]$; one-sided paired Wilcoxon $p=2.19\times {10}^{-4}$). Against the confirmed fixed plan, aggregate error decreases by 8.2%. In comparison experiments designed for two transfer tasks and matched for main PINN training budgets, STCAS achieves the lowest aggregate mean reported error among the compared methods for both a steady convection–diffusion equation and a nonlinear time-dependent Burgers equation; its offline search cost is additional. Full article

High-port-count fiber pump combiners are important passive components for scalable laser diode (LD) power combining in high-power fiber-laser systems. However, increasing the number of input ports from 19 to 37 narrows the fabrication window because fiber bundle packing, taper uniformity, splice matching, thermal management, and backward-light tolerance must be controlled simultaneously. In this work, a 37 × 1 tapered fiber bundle pump combiner was fabricated by a tubing-based method using thirty-seven 135/155 µm multimode input fibers and an 800/880 µm output fiber. The input fibers were weakly etched to improve bundle compactness, and the glass-tube-assisted fiber bundle was tapered, cleaved, and fusion-spliced with a tapered output fiber. The fabricated combiner was characterized using thirty-seven 915 nm fiber-coupled LDs. At a total injected power of 4.89 kW, the combiner delivered 4.80 kW output power, corresponding to an overall transmission efficiency of 98.16%. The single-port transmission efficiencies were approximately in the range of 97.3–98.1%, indicating good port-to-port uniformity for the dense 37-fiber bundle. During full-power operation, the highest temperature appeared in the tapered fiber bundle region and reached 103.8 °C, while the fusion-splice region reached 76.2 °C. In addition, the device withstood 500 W backward-propagating light without observable damage, indicating its practical tolerance to reverse-power loading. These results show that the proposed 37 × 1 fiber pump combiner provides an effective all-fiber solution for multi-kilowatt LD power combining. Full article

Candidatus Hepatincolaceae is a poorly characterized family of obligate Alphaproteobacterial symbionts that are widely detected in ecdysozoans. They were previously assumed to play a nutrient-scavenging role in the gut lumen. In this study, two high-quality metagenome-assembled genomes (MAGs, 1.39 Mb and 1.48 Mb in size) were recovered from the gut of the snapping shrimp Alpheus brevicristatus via metagenomic sequencing. Phylogenetic and whole-genome similarity analyses confirm that these two MAGs represent two novel, undescribed genera within the family Ca. Hepatincolaceae. Metabolic reconstruction reveals that they not only retain the canonical nutrient-scavenging pathways conserved across all Hepatincolaceae members, but also encode previously undocumented functional modules for antioxidant defense, vitamin B₁ and B₂ biosynthesis, and short-chain fatty acid production. They maintain a high oxygen-affinity cytochrome bd terminal oxidase to thrive in the anoxic gut microenvironment. Consistent with their symbiotic lifestyle, their genomes exhibit typical signatures of reductive evolution, such as reduced genome size, low GC content, and gene loss in amino acid and nucleotide de novo biosynthesis pathways. This study presents the first reported high-quality genomes of marine Ca. Hepatincolaceae symbionts, which are predicted to possess multiple metabolic functions extending beyond nutritional mutualism. Full article

Scarab beetles depend on gut microbes for digestive enzymes. Some species’ microbiomes show taxonomic conservation regardless of diet, while others have conserved functional profiles. We compared the hindgut microbiomes of two Cetoniinae beetle larvae: the obligately saproxylophagous Mecynorrhinella poggei and the omnivorous/predatory Goliathus goliatus, which requires protein supplementation when reared artificially. Two diets with and without supplementation were used. If diet drives the microbiome, then gut microbes in protein-supplemented hosts should produce fewer lignocellulolytic enzymes and more proteinases regardless of species. If microbiome composition is conserved within a species, then Mecynorrhinella is expected to have more lignocellulolytic microbes while Goliathus should have more proteinolytic microbes regardless of diet. In this study, low-protein diets reduced G. goliatus growth, but gut microbiome composition and predicted function remained largely stable, dominated by Bacteroidales including Dysgonomonas, Proteiniphilum, and Alistipes. Mecynorrhinella’s gut microbiome showed some reduced Proteiniphilum and increased Dysgonomonas relative abundance, but otherwise the microbiome composition was statistically stable with no effect of diet on growth or predicted microbiome function. These results highlight that microbiomes of closely related insects can markedly differ even if diet does not and that microbiome functional conservation tied to host physiology may occur even if greater plasticity could theoretically reduce malnutrition. Full article

A non-dairy whipping cream was developed by partially replacing cocoa butter substitute with pea protein–high-methoxyl pectin (PP–HMP) emulsion gel containing soybean oil. The effects of substitution levels (10%, 20%, 30%, 40%, and 50%) on the properties of the pre-whipping cream emulsion and the resulting whipped cream were systematically investigated and compared with those of commercial whipped creams. The properties of the pre-whipping emulsion (apparent viscosity and particle size) and whipped cream (hardness, adhesiveness, elastic modulus, and thixotropic loop area) degraded with increasing PP–HMP emulsion gel substitution levels. Overrun and partial coalescence of fat reached their highest values at the 20% substitution level, at which point the whipped cream also exhibited a uniform microstructure and excellent shape retention. The overrun, hardness, and foam stability of non-dairy whipping cream containing 20% PP–HMP emulsion gel were comparable to those of the commercial whipped cream. These findings demonstrate the potential of PP–HMP emulsion gel as a fat substitute for developing non-dairy whipping cream with reduced hydrogenated fat content. Full article

A high manufacturing cost of goods (CoG) remains a critical barrier to the broad clinical adoption of gene therapies and is driven in part by limited productivity in adeno-associated virus (AAV) manufacturing. Here, we report an optimized AAV production process developed to markedly increase upstream titers while preserving vector quality and potency. The process combines a redesigned plasmid system, an optimized plasmid ratio, and a novel synthetic transfection reagent and was benchmarked against a conventional triple-plasmid/PEI MAX workflow. Across multiple AAV capsids and independent production runs, the optimized process reproducibly increased crude harvest titers by approximately 10- to 33-fold relative to the standard process, while maintaining key vector quality attributes. Notably, within the detection limits of the assay, rcAAV was undetectable at 1 × 10¹⁰ vg input with the optimized process, whereas the conventional triple-plasmid (with native Rep-Cap sequence)/PEI MAX workflow remained rcAAV-positive under identical conditions. Importantly, the in vivo potency was comparable to that of vectors produced by the conventional process. These results position our optimized AAV production process as a promising strategy to materially reduce AAV manufacturing CoG per patient. Full article

Background/Objectives: Malignant hyperthermia (MH) is a life-threatening pharmacogenetic disorder of skeletal muscle primarily associated with pathogenic variants in RYR1; however, a substantial proportion of MH-susceptible individuals lack identifiable variants in known genes. This study aimed to identify novel genetic contributors in Ca²⁺-induced Ca²⁺ release (CICR)-positive patients without RYR1 variants and to evaluate their functional relevance. Methods: Among 29 CICR-positive individuals without pathogenic variants identified by gene panel testing, five patients underwent whole-exome sequencing (WES). In one family, heterozygous variants in ANO5 (p.Arg547Gln) and ORAI3 (p.Arg287Cys) were identified. To evaluate their functional significance, intracellular Ca²⁺ dynamics were analyzed in primary myotubes derived from Case 165, an affected individual carrying both variants, and compared with those from CICR-negative controls and CICR-positive patients harboring RYR1 variants. Results: Myotubes derived from Case 165 demonstrated enhanced sensitivity to caffeine and 4-chloro-m-cresol, elevated resting intracellular Ca²⁺ levels, and greater Ca²⁺ reduction under Ca²⁺-free conditions compared with CICR-negative controls, resembling the phenotype observed in the RYR1 variant group. In contrast, dantrolene-induced Ca²⁺ reduction was significantly greater only in the RYR1 variant group. Conclusions: These findings suggest that ANO5 and ORAI3 variants may contribute to abnormal Ca²⁺ regulation in MH-susceptible individuals without RYR1 mutations and highlight the importance of combining genomic analysis with functional validation to identify novel genetic contributors to MH susceptibility. Full article